PSC

By Targets:	AMPK (1) Autophagy (2) Biochemical Assay Reagents (2) Cytochrome P450 (1) Endogenous Metabolite (2) FXR (2) GSK-3 (1) Isotope-Labeled Compounds (1) Monoamine Oxidase (1) P-glycoprotein (1) TGF-β Receptor (1) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (3) Inflammation/Immunology (4) Metabolic Disease (5) Neurological Disease (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17384

Valspodar 10+ Cited Publications PSC 833	P-glycoprotein	Cancer
Valspodar (PSC 833) is a selective P-glycoprotein inhibitor that has been used as an experimental cancer treatment and chemosensitizer.

HY-P99047

Simtuzumab AB 0024; GS 6624	Monoamine Oxidase	Inflammation/Immunology
Simtuzumab (AB 0024; GS 6624) is a monoclonal antibody directed against Lysyl oxidase like-2 (LOXL2). Simtuzumab can be used for the research of primary sclerosing cholangitis (PSC) .

HY-109083

Cilofexor 5+ Cited Publications GS-9674	FXR Autophagy	Inflammation/Immunology
Cilofexor (GS-9674) is a potent, selective and orally active nonsteroidal FXR agonist with an EC₅₀ of 43 nM. Cilofexor has anti-inflammatory and antifibrotic effects. Cilofexor has the potential for primary sclerosing cholangitis (PSC) and nonalcoholic steatohepatitis (NASH) research .

HY-116374A

Glycolithocholic acid sodium Lithocholylglycine sodium	Others	Metabolic Disease
Glycolithocholic acid (Lithocholylglycine) sodium is the sodium salt of Glycolithocholic acid. Glycolithocholic acid is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) .

HY-116374

Glycolithocholic acid Lithocholylglycine	Endogenous Metabolite	Inflammation/Immunology
Glycolithocholic acid (Lithocholylglycine), an endogenous metabolite, is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) .

HY-150787

BMS-986339	FXR Cytochrome P450	Metabolic Disease
BMS-986339 is an orally active, potent FXR agonist. BMS-986339 forms H-bond with His298 and ASN287 residues. BMS-986339 can be used in the research of primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and nonalcoholic steatohepatitis (NASH), anti-fibrosis .

HY-139886

gTPA2-OMe

Others Others

gTPA2-OMe is a potential hole transport layer candidate for perovskite solar cells (PSCs).
HY-125832

PBDB-T

Biochemical Assay Reagents Others

PBDB-T is a wide bandgap polymer donor in Perylene diimide (PDI)-based polymer solar cells (PSCs) .

gTPA2-OMe	Others	Others
gTPA2-OMe is a potential hole transport layer candidate for perovskite solar cells (PSCs).

PBDB-T	Biochemical Assay Reagents	Others
PBDB-T is a wide bandgap polymer donor in Perylene diimide (PDI)-based polymer solar cells (PSCs) .

HY-125831

ITIC-4F	Biochemical Assay Reagents	Others
ITIC-4F is an indacenodithienothiophene (IDTT)-based postfullerene electron acceptor. ITIC-4F has broad applicability in high-efficiency binary and ternary single-junction as well as tandem polymer solar cells (PSCs) .

HY-116374S

Glycolithocholic acid-d4 Lithocholylglycine-d4	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
Glycolithocholic acid-d₄ is the deuterium labeled Glycolithocholic acid. Glycolithocholic acid, an endogenous metabolite, is a glycine-conjugated secondary bile acid and can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) [1][2][3][4].

HY-13418G

Dorsomorphin dihydrochloride Compound C dihydrochloride; BML-275 dihydrochloride	AMPK	Neurological Disease Cancer
Dorsomorphin dihydrochloride (GMP) is the GMP level of Dorsomorphin dihydrochloride (HY-13418). GMP guidelines are used to produce Dorsomorphin dihydrochloride (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. Dorsomorphin dihydrochloride (GMP) is a potent, selective and ATP-competitive AMPK inhibitor. Dorsomorphin dihydrochloride (GMP) can be used for the research of induced differentiation of pluripotent stem cells (PSCs) .

HY-10182G

Laduviglusib CHIR-99021; CT99021	GSK-3 Wnt β-catenin Autophagy	Metabolic Disease Cancer
Laduviglusib (CHIR-99021) (GMP) is Laduviglusib (HY-10182) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Laduviglusib is a potent, orally active and selective GSK-3α/β inhibitor.

HY-13012G

RepSox E-616452; SJN 2511	TGF-β Receptor	Metabolic Disease
RepSox (E-616452) (GMP) is a RepSox (HY-13012) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. RepSox is a potent and selective TGF-β-RI/ALK5 inhibitor .

Cat. No.	Product Name	Type

HY-10182G

Laduviglusib (GMP) CHIR-99021 (GMP); CT99021 (GMP)	Fluorescent Dye
Laduviglusib (CHIR-99021) (GMP) is Laduviglusib (HY-10182) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Laduviglusib is a potent, orally active and selective GSK-3α/β inhibitor.

HY-13012G

RepSox (GMP) E-616452 (GMP); SJN 2511 (GMP)	Fluorescent Dye
RepSox (E-616452) (GMP) is a RepSox (HY-13012) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. RepSox is a potent and selective TGF-β-RI/ALK5 inhibitor .

HY-13418G

Dorsomorphin dihydrochloride (GMP) Compound C dihydrochloride (GMP); BML-275 dihydrochloride (GMP)	Fluorescent Dye
Dorsomorphin dihydrochloride (GMP) is the GMP level of Dorsomorphin dihydrochloride (HY-13418). GMP guidelines are used to produce Dorsomorphin dihydrochloride (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. Dorsomorphin dihydrochloride (GMP) is a potent, selective and ATP-competitive AMPK inhibitor. Dorsomorphin dihydrochloride (GMP) can be used for the research of induced differentiation of pluripotent stem cells (PSCs) .

Dorsomorphin dihydrochloride (GMP)

Compound C dihydrochloride (GMP); BML-275 dihydrochloride (GMP)

Fluorescent Dye

Dorsomorphin dihydrochloride (GMP) is the GMP level of Dorsomorphin dihydrochloride (HY-13418). GMP guidelines are used to produce Dorsomorphin dihydrochloride (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. Dorsomorphin dihydrochloride (GMP) is a potent, selective and ATP-competitive AMPK inhibitor. Dorsomorphin dihydrochloride (GMP) can be used for the research of induced differentiation of pluripotent stem cells (PSCs) .

Cat. No.	Product Name	Type

HY-10182G

Laduviglusib (GMP) CHIR-99021 (GMP); CT99021 (GMP)	Biochemical Assay Reagents
Laduviglusib (CHIR-99021) (GMP) is Laduviglusib (HY-10182) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Laduviglusib is a potent, orally active and selective GSK-3α/β inhibitor.

HY-13012G

RepSox (GMP) E-616452 (GMP); SJN 2511 (GMP)	Biochemical Assay Reagents
RepSox (E-616452) (GMP) is a RepSox (HY-13012) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. RepSox is a potent and selective TGF-β-RI/ALK5 inhibitor .

HY-13418G

Dorsomorphin dihydrochloride (GMP) Compound C dihydrochloride (GMP); BML-275 dihydrochloride (GMP)	Biochemical Assay Reagents
Dorsomorphin dihydrochloride (GMP) is the GMP level of Dorsomorphin dihydrochloride (HY-13418). GMP guidelines are used to produce Dorsomorphin dihydrochloride (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. Dorsomorphin dihydrochloride (GMP) is a potent, selective and ATP-competitive AMPK inhibitor. Dorsomorphin dihydrochloride (GMP) can be used for the research of induced differentiation of pluripotent stem cells (PSCs) .

Dorsomorphin dihydrochloride (GMP)

Compound C dihydrochloride (GMP); BML-275 dihydrochloride (GMP)

Biochemical Assay Reagents

Dorsomorphin dihydrochloride (GMP) is the GMP level of Dorsomorphin dihydrochloride (HY-13418). GMP guidelines are used to produce Dorsomorphin dihydrochloride (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. Dorsomorphin dihydrochloride (GMP) is a potent, selective and ATP-competitive AMPK inhibitor. Dorsomorphin dihydrochloride (GMP) can be used for the research of induced differentiation of pluripotent stem cells (PSCs) .

Cat. No.	Product Name	Target	Research Area

HY-P99047

Simtuzumab AB 0024; GS 6624	Monoamine Oxidase	Inflammation/Immunology
Simtuzumab (AB 0024; GS 6624) is a monoclonal antibody directed against Lysyl oxidase like-2 (LOXL2). Simtuzumab can be used for the research of primary sclerosing cholangitis (PSC) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-116374

Glycolithocholic acid Lithocholylglycine	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Endogenous Metabolite
Glycolithocholic acid (Lithocholylglycine), an endogenous metabolite, is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) .

Cat. No.	Compare	Product Name	Species	Source

HY-P75988

	PSMA3 Protein, Human (His) Proteasome subunit alpha type-3; Macropain subunit C8; PSMA3; HC8; PSC8	Human	E. coli
	PSMA3 is a protein involved in protein degradation. PSMA3 Protein, Human (His) is the recombinant human-derived PSMA3 protein, expressed by E. coli , with N-His labeled tag. The total length of PSMA3 Protein, Human (His) is 255 a.a., with molecular weight of ~30 kDa.


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Cat. No.	Product Name	Chemical Structure

HY-116374S

Glycolithocholic acid-d4
Glycolithocholic acid-d₄ is the deuterium labeled Glycolithocholic acid. Glycolithocholic acid, an endogenous metabolite, is a glycine-conjugated secondary bile acid and can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) [1][2][3][4].

Cat. No.	Product Name	Application	Reactivity

HY-P82639

PSMA2 Antibody (YA2384)

HC3; PMSA2; Proteasome component C3; PSC2; PSC3; psmA2
WB, IHC-P, ICC/IF, FC Human, Mouse, Rat
HY-P81999

Proteasome alpha 2 Antibody (YA1744)

HC3; PMSA2; Proteasome component C3; PSC2; PSC3; psmA2
WB, IHC-F, IHC-P, ICC/IF Human, Mouse, Rat
HY-P82020

PSMA4 Antibody (YA1765)

proteasome subunit alpha 4; HC9; PSC9; HsT17706
WB, IHC-F, IHC-P, ICC/IF, IP Human, Mouse, Rat
HY-P82556

PSMA1 Antibody (YA2301)

NU; HC2; PROS30; psmA1; PSC2; Proteasome 20S C2
WB, IHC-P, ICC/IF, IP, FC Human, Mouse, Rat

HY-P82641

PSMA3 Antibody (YA2386) PSMA3; HC8; PSC8; Proteasome subunit alpha type-3; Macropain subunit C8; Multicatalytic endopeptidase complex subunit C8; Proteasome component C8	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat

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Biochemical Assay Reagents

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