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Peptide YY

" in MCE Product Catalog:

By Targets:	Neuropeptide Y Receptor (8)
By Research Areas:	Endocrinology (2) Metabolic Disease (5) Neurological Disease (4)

8

Inhibitors & Agonists

7

Peptides

Targets Recommended: Formyl Peptide Receptor (FPR) CGRP Receptor Amyloid-β

Cat. No.	Product Name	Target	Research Areas

Peptide YY (pig)	Neuropeptide Y Receptor	Endocrinology Metabolic Disease
Peptide YY (pig) is a 36 amino acid gastrointestinal peptide, can be isolated from porcine duodenum. Peptide YY (pig) decreases appetite and food-intake by activation of the Y2 receptor. Peptide YY (pig) is present mainly in pancreatic endocrine cells with effect on both intestinal motility and the cardiovascular system.

Peptide YY (PYY), human	Neuropeptide Y Receptor	Metabolic Disease Neurological Disease Endocrinology
Peptide YY (PYY) is a gut hormone that regulates appetite and inhibits pancreatic secretion. Peptide YY (PYY) can mediate its effects through the Neuropeptide Y receptors.

Peptide YY (PYY) (3-36), Human	Neuropeptide Y Receptor	Metabolic Disease
Peptide YY (PYY) (3-36), Human is an endogenous appetite suppressing peptide. Peptide YY (PYY) (3-36), Human, a neuropeptide Y (NPY) Y2 receptor agonist, is a powerful inhibitor of intestinal secretion.

Peptide YY (PYY) (3-36), porcine	Neuropeptide Y Receptor	Metabolic Disease
Peptide YY (PYY) (3-36), porcine is a gut hormone peptide that acts as a Y2 receptor agonist to reduce appetite.

Peptide YY (PYY) (3-36), porcine TFA	Neuropeptide Y Receptor	Metabolic Disease
Peptide YY (PYY) (3-36), porcine TFA is a gut hormone peptide that acts as a Y2 receptor agonist to reduce appetite.

*(Pro34)-Peptide* YY (human)**	Neuropeptide Y Receptor	Neurological Disease
(Pro34)-Peptide YY (human) is a highly Y₁-selective full agonist of Peptide YY (HY-P1514)/neuropeptide Y receptors.

*(Leu31,Pro34)-Peptide* YY (human)**	Neuropeptide Y Receptor	Neurological Disease
(Leu31,Pro34)-Peptide YY (human) is a Peptide YY (HY-P1514) derivative and is a potent and selective Y₁ agonist with a K_D of 1.0 nM.

JNJ-5207787	Neuropeptide Y Receptor	Neurological Disease
JNJ-5207787 is a nonpeptidic, selective and penetrate the blood-brain barrier neuropeptide Y Y₂ receptor (Y₂) antagonist. JNJ-5207787 inhibits the binding of peptide YY (PYY) with pIC₅₀s of 7.0 and 7.1 for human Y₂ receptor and rat Y₂ receptor, respectively. JNJ-5207787 is >100-fold selective versus human Y₁, Y₄, and Y₅ receptors.

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