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Peroxidase

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-125859
    Peroxidase, Horseradish
    1 Publications Verification

    Reactive Oxygen Species Inflammation/Immunology Endocrinology
    Peroxidase, Horseradish actively involves in oxidizing reactive oxygen species, innate immunity, hormone biosynthesis and pathogenesis of several diseases .
    <em>Peroxidase</em>, Horseradish
  • HY-132183

    Endogenous Metabolite Metabolic Disease
    Chloride peroxidase is a monomeric, heme-containing enzyme. Chloride peroxidase is capable of electrophilic chlorinations through the umpolung of chloride by oxidation with hydrogen peroxide .
    Chloride <em>peroxidase</em>
  • HY-132188

    Endogenous Metabolite Others
    Manganese peroxidase is a heme protein that oxidizes Mn2+ to Mn3+. Manganese peroxidase catalyzes plant lignin de-polymerization. Manganese peroxidase can be used for the biodegradation of hazardous environmental contaminants, and especially for dye wastewater decolorization .
    Manganese <em>peroxidase</em>
  • HY-P2833

    GSH-Px; EC 1.11.1.9

    Glutathione Peroxidase Others
    Glutathione Peroxidase (GSH-Px; EC 1.11.1.9) belongs to the peroxidase family and is commonly used in biochemical research. Glutathione Peroxidase can catalyze reduced glutathione (GSH) to form a disulfide bridge with another glutathione molecule, convert it into oxidized glutathione (GSSG), and react with hydrogen peroxide or lipid peroxide reaction, reducing it to H2O. Glutathione Peroxidase is an effective antioxidant against oxidative stress .
    Glutathione <em>Peroxidase</em>
  • HY-W105101

    Others Others
    3,5-Dibromotyrosine is a product of protein oxidation by eosinophil peroxidase .
    3,5-Dibromotyrosine
  • HY-145197

    Glutathione Peroxidase Cardiovascular Disease
    MPO-IN-3 is a potent myeloperoxidase (MPO) inhibitor (WO2013068875A1, example 191). Myeloperoxidase (MPO) is a heme-containing enzyme belonging to the peroxidase superfamily .
    MPO-IN-3
  • HY-W411361

    PCNPH

    Fluorescent Dye Cancer
    Pyridine-2-carboxaldehyde 4-nitrophenylhydrazone (PCNPH) is a chromogenic substrate to peroxidase enzymes. Pyridine-2-carboxaldehyde 4-nitrophenylhydrazone can form a purple indamine dye with peroxidase enzymes and peroxides .
    Pyridine-2-carboxaldehyde 4-nitrophenylhydrazone
  • HY-W455884

    Others Others
    3,5-Dichloro-2-hydroxybenzenesulfonic acid is used in conjunction with Ampyrone (HY-B1398) (4-AAP) and hydrogen peroxide (H2O2) for chromogenic quantification of peroxidase in coupled enzymatic reactions. 3,5-Dichloro-2-hydroxybenzenesulfonic acid is used to measure hydrogen peroxide production in conjunction with peroxidase .
    3,5-Dichloro-2-hydroxybenzenesulfonic acid
  • HY-W007967

    Others Others
    4-Chloronaphthalen-1-ol is a substrate of horseradish peroxidase. 4-Chloronaphthalen-1-ol can be used to visualize protein bands in western blotting .
    4-Chloro-1-naphthol
  • HY-107858

    3,4-Dimethoxybenzyl alcohol

    Endogenous Metabolite Others
    Veratryl alcohol (3,4-Dimethoxybenzenemethanol), a secondary metabolite of some lignin degrading fungi, is commonly used nonphenolic substrate for assaying ligninolytic activity .Veratryl alcohol protects lignin peroxidase (LiP) from H2O2-dependent inactivation and prevents LiP compound III accumulation
    Veratryl alcohol
  • HY-139381

    MitoPeroxidase 2

    Apoptosis Metabolic Disease
    MitoEbselen-2 chloride (MitoPeroxidase 2), a mitochondria-targeted mimic of glutathione peroxidase, is a radiation mitigator. MitoEbselen-2 chloride is effective in reducing lipid hydroperoxides, preventing apoptotic cell death .
    MitoEbselen-2 chloride
  • HY-125859B

    Bacterial Infection
    Lactoperoxidase, bovine milk is an antimicrobial protein that belongs to the mammalian heme peroxidase family. Lactoperoxidase, bovine milk uses H2O2 to catalyze the oxidation of its preferred halide substrates including I , Br , F , or the pseudohalide SCN .
    Lactoperoxidase, bovine milk
  • HY-W012568

    Others Others
    1-Methoxynaphthalene is used as the substrate to investigate the activity of cytochrome c peroxidase (CcP). 1-Methoxynaphthalene also can be used to synthesize prenyl naphthalen-ols .
    1-Methoxynaphthalene
  • HY-N0224A

    (S)-Goitrin; L-5-Vinyl-2-thiooxazolidone

    Influenza Virus Metabolic Disease
    Goitrin ((S)-Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity .
    Goitrin
  • HY-141809
    GPX4-IN-3
    1 Publications Verification

    Glutathione Peroxidase Ferroptosis Cancer
    GPX4-IN-3 (26a) is a potent glutathione peroxidase 4 (GPX4) inhibitor as a selective ferroptosis inducer. GPX4-IN-3 (26a) exhibits 71.7% inhibition for GPX4 with 1 μM .
    GPX4-IN-3
  • HY-152259

    TMV Infection
    TMV-IN-4 (compound 3) is a tobacco mosaic virus (TMV) inhibitor that effectively induces resistance and enhances plant tolerance to TMV infection by interacting with TMV helicase. TMV-IN-4 enhances peroxidase and superoxide dismutase activity, thereby increasing resistance to TMV in tobacco .
    TMV-IN-4
  • HY-B1000A
    L-SelenoMethionine
    1 Publications Verification

    Endogenous Metabolite Apoptosis Cancer
    L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase .
    L-SelenoMethionine
  • HY-D1840

    Biochemical Assay Reagents Others
    Tyramide Amplification Buffer is a ready-to-use buffer primarily intended for immunostaining of cells and tissues by the technique of tyramide signal amplification (TSA). TSA Technology is based on a tyrosinase labeling system that reacts a tyrosine-labeled antibody with a fluorescently labeled tyramide using peroxidase to form a highly amplified fluorescent signal. For example, horseradish peroxidase (HRP) can catalyze the reaction of tyrosine and hydrogen peroxide under milder conditions to generate epoxy groups. Epoxy groups promote the binding of tyramide to adjacent amino acids to form fluorescently labeled products .
    Tyramide Amplification Buffer
  • HY-D1839

    Biotin Tyramide

    Fluorescent Dye Others
    Biotin TSA(200×) (Biotin Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
    Biotin TSA(200×)
  • HY-138153

    Glutathione Peroxidase Ferroptosis Cancer
    JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and an active metabolite of GPX4 inhibitor ML-210. JKE-1674, an analog of ML-210 in which the nitroisoxazole ring is replaced with an α-nitroketoxime. JKE-1674 can convert into a nitrile oxide JKE-1777. JKE-1674 kills LOX-IMVI cells in a manner that is equipotent to ML-210 and is completely rescued by ferroptosis inhibitors .
    JKE-1674
  • HY-D1832

    VF 532 Tyramide

    Fluorescent Dye Others
    Vari Fluor 532 TSA (200×) (VF 532 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
    Vari Fluor 532 TSA (200×)
  • HY-D1833

    VF 680 Tyramide

    Fluorescent Dye Others
    Vari Fluor 680 TSA (200×) (VF 680 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
    Vari Fluor 680 TSA (200×)
  • HY-139915

    Glutathione Peroxidase Inflammation/Immunology
    MPO-IN-1 is a potent, orally active, and irreversible indole-containing inhibitor of myeloperoxidase (MPO). MPO-IN-1 has IC50s of 2.6 μM and 5.3 μM for MPO and thyroid peroxidase (TPO), respectively. MPO-IN-1 inhibits MPO activity in an acute mouse model of inflammation .
    MPO-IN-1
  • HY-D1834

    VF 640 Tyramide

    Fluorescent Dye Others
    Vari Fluor 640 TSA(200×) (VF 640 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
    Vari Fluor 640 TSA(200×)
  • HY-D1835

    VF 594 Tyramide

    Fluorescent Dye Others
    Vari Fluor 594 TSA(200×) (VF 594 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
    Vari Fluor 594 TSA(200×)
  • HY-D1831

    VF 620 Tyramide

    Fluorescent Dye Others
    Vari Fluor 620 TSA(200×) (VF 620 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
    Vari Fluor 620 TSA(200×)
  • HY-D1837

    VF 488 Tyramide

    Fluorescent Dye Others
    Vari Fluor 488 TSA(200×) (VF 488 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
    Vari Fluor 488 TSA(200×)
  • HY-D1838

    VF 350 Tyramide

    Fluorescent Dye Others
    Vari Fluor 350 TSA(200×) (VF 350 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
    Vari Fluor 350 TSA(200×)
  • HY-15902
    ABTS diammonium salt
    2 Publications Verification

    AzBTS-(NH4)2

    Fluorescent Dye Others
    ABTS diammonium salt is a substrate for horseradish peroxidase (HRP) conjugate.
    ABTS diammonium salt
  • HY-B1398
    Ampyrone
    1 Publications Verification

    4-Aminophenazone

    COX Drug Metabolite Others
    Ampyrone is a reagent for glucose determination in the presence of peroxidase and phenol.
    Ampyrone
  • HY-13750
    Ebselen
    10+ Cited Publications

    SPI-1005; PZ-51; CCG-39161

    Calcium Channel Virus Protease HIV Phosphatase Infection Neurological Disease Inflammation/Immunology Cancer
    Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker . Ebselen potently inhibits M pro (IC50=0.67 μM) and COVID-19 virus (EC50=4.67 μM) .Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen, an organoselenium compound, can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity .
    Ebselen
  • HY-D1740

    DHTM Ros

    Fluorescent Dye Others
    Dihydrotetramethylrosamine (DHTM Ros) is a fluorogenic substrate for peroxidase that oxidizes to fluorescent tetramethylrosamine chloride.
    Dihydrotetramethylrosamine
  • HY-101880

    10-Acetyl-3,7-dihydroxyphenoxazine

    Fluorescent Dye Others
    ADHP is a fluorogenic peroxidase substrate (λex=530 nm, λem=590 nm).
    ADHP
  • HY-B1398S

    4-Aminoantipyrine-d3

    COX Drug Metabolite Others
    Ampyrone-d3 is the deuterium labeled Ampyrone. Ampyrone is a reagent for glucose determination in the presence of peroxidase and phenol.
    Ampyrone-d3
  • HY-W000357

    Biochemical Assay Reagents Others
    4-(Imidazol-1-yl)phenol is a highly potent signal enhancer in a horseradish peroxidase (HRP)-luminol chemiluminescence (CL) immunoassay .
    4-(Imidazol-1-yl)phenol
  • HY-15914

    DCHBS

    Fluorescent Dye Others
    DHBS is Used in conjunction with 4-aminoantipyrine (4-AAP) and hydrogen peroxide (H2O2) for chromogenic quantitation of peroxidase in coupled enzymatic reactions.
    DHBS
  • HY-139199

    Drug Metabolite Others
    4-Hydroxyphenylbutazone is a metabolite of Phenylbutazone. Phenylbutazone, a nonsteroidal anti-inflammatory agent (NSAID), is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS) .
    4-Hydroxyphenylbutazone
  • HY-W143216

    Monomethylthionine

    Others Others
    Azure C is the product of sequential enzymatic oxidation of Methylene blue (MB) or Azure B (AB). Azure C serves as the substrate of horseradish peroxidase (HRP) .
    Azure C
  • HY-B0329
    Isoniazid
    3 Publications Verification

    INH; Isonicotinic acid hydrazide; Isonicotinic hydrazide

    Bacterial Autophagy Mitophagy Antibiotic Infection
    Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity .
    Isoniazid
  • HY-100002
    ML162
    3 Publications Verification

    Glutathione Peroxidase Ferroptosis Cancer
    ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor. ML162 has a selective lethal effect on mutant RAS oncogene-expressing cell lines
    ML162
  • HY-D2205

    Cy7 TSA

    Fluorescent Dye Others
    Cy7 tyramide, a red fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids.
    Cy7 tyramide
  • HY-113402

    γ-Glu-Cys

    Endogenous Metabolite Inflammation/Immunology
    Gamma-glutamylcysteine (γ-Glutamylcysteine), a dipeptide containing cysteine and glutamic acid, is a precursor to glutathione (GSH). Gamma-glutamylcysteine is a cofactor for glutathione peroxidase (GPx) to increase GSH levels .
    Gamma-glutamylcysteine
  • HY-112841

    3-(10′-Phenothiazinyl)propane-1-sulfonate sodium; SPTZ sodium

    Others Cancer
    PTZ-343 is a potent enhancer of Luminol (HY-15922). PTZ-343 greatly increases the light output of the peroxidase-catalyzed luminol chemiluminescent oxidation reaction (>80%) .
    PTZ-343
  • HY-162065

    Ferroptosis Cancer
    N6F11 is a ferroptosis inducer, and can trigger the degradation of glutathione peroxidase 4 (GPX4) specifically in cancer cells. N6F11 can be used for ferroptosis study .
    N6F11
  • HY-W012145

    Others Metabolic Disease
    TMPD dihydrochloride, a readily oxidizable compound, is an enzymatically convert redox active substrate molecule. TMPD dihydrochloride is also an electron donor and serves as a reducing cosubstrate for heme peroxidases . TMPD dihydrochloride is also a complex IV substrate .
    TMPD dihydrochloride
  • HY-136247

    Tyramide-Cy5

    DNA Stain Others
    Cyanine 5 Tyramide (Tyramide-Cy5), a red fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids .
    Cyanine 5 Tyramide
  • HY-136248

    Tyramide-Cy3

    DNA Stain Fluorescent Dye Others
    Cyanine 3 Tyramide (Tyramide-Cy3), an orange fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids .
    Cyanine 3 Tyramide
  • HY-100003
    ML-210
    5+ Cited Publications

    ML-210 is a selective and covalent glutathione peroxidase 4 (GPX4) inhibitor with an EC50 of 30 nM. ML-210 binds the GPX4 selenocysteine residue. ML-210 has anti-cancer activity .
    ML-210
  • HY-155639

    Others Others
    Tyramide alkyne is an alternative labeling substrate that can be coupled to detection or enrichment moieties via a Copper-catalyzed Azide/Alkyne Cycloaddition (CuAAC) “click” reaction. Tyramide alkyne can be used for ascorbate peroxidase 2 (APEX2) labeling .
    Tyramide alkyne
  • HY-B0329S

    INH-d4; Isonicotinic acid hydrazide-d4; Isonicotinic hydrazide-d4

    Bacterial Autophagy Mitophagy Antibiotic Infection
    Isoniazid-d4 is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity[1][2][3][4].
    Isoniazid-d4

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