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Results for "

Phosphatase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Phosphatase (192) PTEN (4) SHP2 (18) 5-HT Receptor (2) Akt (4) Aldose Reductase (1) Amyloid-β (1) Androgen Receptor (1) Antibiotic (20) Apoptosis (29) ATM/ATR (1) Autophagy (7) Bacterial (14) Beta-secretase (1) Biochemical Assay Reagents (9) Calcineurin (3) CaMK (1) Carbonic Anhydrase (1) CDK (1) Cholinesterase (ChE) (3) Complement System (2) COX (1) Cytochrome P450 (2) DNA/RNA Synthesis (2) Dopamine β-hydroxylase (1) EBV (1) EGFR (1) Endogenous Metabolite (15) Epoxide Hydrolase (1) ERK (2) FKBP (3) Fluorescent Dye (9) Fungal (7) Glucosidase (2) Histone Methyltransferase (2) HIV (1) HSP (2) HSV (1) IAP (1) iGluR (2) Influenza Virus (1) Isotope-Labeled Compounds (5) Leukotriene Receptor (1) MAP3K (1) MAPKAPK2 (MK2) (2) MEK (1) Molecular Glues (1) Monoamine Oxidase (2) Notch (1) Nuclear Factor of activated T Cells (NFAT) (1) Parasite (15) PERK (1) Phosphodiesterase (PDE) (1) Phospholipase (1) PI3K (1) PKC (2) Progesterone Receptor (1) PROTACs (1) Protease Activated Receptor (PAR) (1) Pyk2 (1) Raf (2) Ras (1) Reactive Oxygen Species (4) Reverse Transcriptase (2) SARS-CoV (2) Ser/Thr Protease (2) Sirtuin (2) Thyroid Hormone Receptor (1) Tie (1) Topoisomerase (2)
By Research Areas:	Cancer (116) Cardiovascular Disease (8) Endocrinology (8) Infection (30) Inflammation/Immunology (35) Metabolic Disease (63) Neurological Disease (26)
Click Chemistry:	Alkynes (3)

288

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

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Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

*Alkaline phosphatase, Bovine intestine* 1 Publications Verification Apase	Endogenous Metabolite	Metabolic Disease Cancer
Alkaline phosphatase, Bovine intestine (Apase) is a membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase can be used in molecular biology and enzyme-free analysis. Inhibition of tissue nonspecific alkaline phosphatase can block intracellular lipid accumulation .

*Acid phosphatase, wheat* ACP	Endogenous Metabolite	Metabolic Disease
Acid phosphatase, wheat (ACP) is an enzyme that removes phosphate from other molecules during digestion. Acid phosphatase catalyzes the conversion of orthophosphoric monoester and H2O to alcohol and phosphoric acid .

Phosphatase Binder-1	Others	Cancer
Phosphatase Binder-1 (comppund i-196) provides bifunctional compounds that efficiently dephosphorylate certain phospho-activated target proteins. Phosphatase Binder-1 plays an important role in cancer .

Phosphatase-IN-1	Phosphatase Fungal	Infection
Phosphatase-IN-1 (compound II-8), a propranolol (HY-B0573B) derivative, is a *phosphatidate phosphatase* (Pah)** inhibitor. Phosphatase-IN-1 can binds to MoPah1, with an affinity constant of 19.8 μM. Phosphatase-IN-1 inhibits growth of plant pathogens and shows anti-fungal ability. Phosphatase-IN-1 is not toxic to rice seedlings and wheat heads .

Thymolphthalein monophosphate disodium hydrate	Phosphatase	Others
Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum .

4-Methylsalicylic acid	IAP	Inflammation/Immunology
4-Methylsalicylic acid is a salicylic acid. 4-Methylsalicylic acid derivative is a selective tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP) inhibitor .

Fast Red Violet LB	Fluorescent Dye	Others
Fast Red Violet LB is a dye for staining tartrate resistant acid phosphatase (TRAP). Fast Red Violet LB can be used for alkaline phosphatase (ALP) activity staining .

Fast Red Violet LB Zinc chloride	Fluorescent Dye	Others
Fast Red Violet LB Zinc chloride is a stain that stains tartrate-resistant acid phosphatase (TRAP) and Fast Red Violet LB Zinc chloride can be used to stain alkaline phosphatase (ALP) activity .

Dibefurin	Phosphatase Endogenous Metabolite	Others
Dibefurin is a fungal metabolite that acts as an inhibitor of calcineurin phosphatase .

DiFMUP 6,8-Difluoro-4-methylumbelliferyl phosphate	Phosphatase	Others
DiFMUP is a fluorogenic substrate, and has been widely used for the continuous detection of phosphatase activities. DiFMUP is hydrolysis by a phosphatase results in the release of Xuorescent DIFMU, which can be easily followed in continuous mode by a Xuorescence reader .

Sydowimide A	Phosphatase	Inflammation/Immunology
Sydowimide A is a potent inhibitor of Src homology region 2 domain-containing phosphatase-1 (SHP1), T-cell protein tyrosine phosphatase (TCPTP) and leukocyte common antigen (CD45), with IC₅₀ values of 1.5, 2.4 and 18.83 μM, respectively .

MLS000544460	Phosphatase	Cancer
MLS000544460 is a highly selective and reversible Eya2 phosphatase inhibitor with a K_d of 2.0 μM and an IC₅₀ of 4 μM. MLS000544460 inhibit Eya2 phosphatase mediated cell migration and has anti-cancer activity .

PTP inhibitor 1	Phosphatase	Cancer
PTP inhibitor 1 is a *protein tyrosine phosphatase* (PTP)** inhibitor, with anti-angiogenic effect .

PP5-IN-1	Phosphatase Apoptosis	Cancer
PP5-IN-1 (Compound P053) is a competitive inhibitor of *Serine/threonine protein phosphatase-5 (PP5)* that binds to its catalytic domain and causes apoptosis in renal cancer .

CDP-Star	Biochemical Assay Reagents Phosphatase	Others
CDP-Star is a chemiluminescent substrate for alkaline phosphatase. CDP-Star can be used for enzyme-linked immunoassays .

PAP 248–286 Prostatic Acid Phosphatase(248-286)	HIV	Others
PAP 248–286 is a biological active peptide. (Prostatic Acid Phosphatase (248-286), PAP (248-286) peptide is a semen-derived enhancer of viral infection (SEVI) factor found in semen. This peptide greatly increases HIV infection through enhanced virion attachment to target cells.)

NSC 295642	PERK Phosphatase	Cancer
NSC 295642 is a *phosphatase* inhibitor. NSC 295642 can significantly increase phospho-Erk cytonuclear differences in intact cells. NSC 295642 can be used for the research of cancer .

Cefsulodin sodium SCE-129 sodium	Bacterial Antibiotic	Infection
Cefsulodin (SCE-129) sodium is a third generation β lactam antibiotic and member of the cephems subgroup of antibiotics. Cefsulodin sodium inhibits cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) cross-linking and transpeptidation of peptidogly. Cefsulodin sodium is a potent tyrosine phosphatase inhibitor against mPTPB, a virulent phosphatase from Mycobacterium tuberculosis, with an IC₅₀ value of 16 μM .

Thienopyridone	Phosphatase Apoptosis	Cancer
Thienopyridone is a potent and selective **phosphatase of regenerating liver (PRL) phosphatase inhibitor with IC₅₀s of 173 nM, 277 nM and 128 nM for PRL-1, PRL-2, and PRL-3*, respectively. Thienopyridone shows minimal effects on other phosphatases. Thienopyridone induces p130Cas cleavage and apoptosis* and has anticancer effects .

LTV-1	Phosphatase	Inflammation/Immunology
LTV-1 is a potent lymphoid tyrosine phosphatase (LYP) inhibitor in T cells with an IC₅₀ of 508 nM. LTV-1 has the potential for autoimmunity treatment .

ML120 analog 1	Phosphatase	Cancer
ML120 analog 1 (compound 1) is a competitive inhibitor with a K_i of 0.69 μM for *Hematopoietic protein tyrosine phosphatase* (HePTP)** .

4-Methylumbelliferyl phosphate 4-MUP; MUP	Phosphatase	Others
4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline *phosphatase* fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant .

Calcium glycerophosphate	Phosphatase	Metabolic Disease
Calcium glycerophosphate is an inhibitor of *intestinal alkaline phosphatase* F3**. Calcium glycerophosphate is a source of calcium and phosphorus in total parenteral nutrition solutions .

BCI-215 2 Publications Verification	Phosphatase	Cancer
BCI-215 is a potent and tumor cell-selective *dual specificity MAPK phosphatase* (DUSP-MKP)** inhibitor. BCI-215 has cytotoxicity for tumor cells but not normal cells .

LMPTP inhibitor 1	Phosphatase	Metabolic Disease
LMPTP inhibitor 1 is a selective inhibitor of low molecular weight protein tyrosine phosphatase (LMPTP), with an IC₅₀ of 0.8 μM LMPTP-A.

4-Nitrophenyl phosphate disodium hexahydrate 2 Publications Verification p-Nitrophenyl phosphate disodium hexahydrate	Biochemical Assay Reagents	Others
4-Nitrophenyl phosphate (p-nitrophenyl phosphate) disodium hexahydrate is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. 4-Nitrophenyl phosphate disodium hexahydrate is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm .

EGF Receptor Substrate 2 (Phospho-Tyr5) (TFA)	Phosphatase Biochemical Assay Reagents	Others
EGF Receptor Substrate 2 (Phospho-Tyr5) acetate, a biologically active peptide, is a tyrosine phosphate substrate. EGF Receptor Substrate 2 (Phospho-Tyr5) acetate can be used to detect protein tyrosine phosphatases activity .

EGF Receptor Substrate 2 (Phospho-Tyr5) (acetate)	Phosphatase Biochemical Assay Reagents	Others
EGF Receptor Substrate 2 (Phospho-Tyr5) acetate, a biologically active peptide, is a tyrosine phosphate substrate. EGF Receptor Substrate 2 (Phospho-Tyr5) acetate can be used to detect protein tyrosine phosphatases activity .

MY10	Phosphatase	Neurological Disease
MY10 is a potent and orally active *receptor protein tyrosine phosphatase* (RPTPβ/ζ)** inhibitor. MY10 attenuates binge-like ethanol consumption and ethanol reward .

PAP-IN-1	Others	Others
PAP-IN-1 (compound 28) is an inhibitor of purple acid phosphatases (PAPs), a ubiquitous binuclear metallohydrolase. PAP-IN-1 inhibits mammalian PAP with K_i value of 168 nM. PAP-IN-1 targets to pig PAP with K_ic value of 0.17 μM. PAP inhibitors can be used for research of anti-osteoporotic drugs .

NSC45586 sodium	Akt Ser/Thr Protease	Neurological Disease Cancer
NSC45586 sodium is an inhibitor of *pleckstrin homology domain and leucine-rich repeat protein phosphatase* (PHLPP)*. NSC45586 sodium targets the PP2C phosphatase* domain in PHLPP1 and PHLPP2. NSC45586 sodium can activate AKT in neurons .

NSC45586	Akt Ser/Thr Protease	Neurological Disease Cancer
NSC45586 is an inhibitor of *pleckstrin homology domain and leucine-rich repeat protein phosphatase* (PHLPP)*. NSC45586 targets the PP2C phosphatase* domain in PHLPP1 and PHLPP2. NSC45586 can activate AKT in neurons .

Ethoxysanguinarine 1 Publications Verification	Apoptosis	Cancer
Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine is an inhibitor of *protein phosphatase* 2A (CIP2A). Ethoxysanguinarine induces cell apoptosis** and inhibits colorectal cancer cells growth .

PTP1B-IN-4	Phosphatase	Metabolic Disease
PTP1B-IN-4 is a non-competitive allosteric inhibitor of the protein tyrosine phosphatase PTP1B, with an IC₅₀ of 8 μM. PTP1B-IN-4 is potentail for the research of obesity and diabetes .

Calcineurin autoinhibitory peptide	Phosphatase	Neurological Disease
Calcineurin autoinhibitory peptide is a selective inhibitor of *Ca ²⁺/calmodulin-dependent protein phosphatase* (calcineurin), with an IC₅₀** of ~10 μM. Calcineurin autoinhibitory peptide could protect neurons from excitatory neuronal death .

Cyanidin 3-arabinoside	Phosphatase	Metabolic Disease
Cyanidin 3-arabinoside is a selective and reversible *protein tyrosine phosphatase* 1B (PTP1B) inhibitor, with an IC₅₀** of 8.91 μM. Cyanidin 3-arabinoside is potential for the research of type 2 diabetes .

SMAP-2 DT-1154	Phosphatase	Cancer
SMAP-2 (DT-1154) is an orally active *protein phosphatase* 2A (PP2A)** activator, with anti-cancer activity .

Calcineurin autoinhibitory peptide TFA	Phosphatase	Neurological Disease
Calcineurin autoinhibitory peptide TFA is a selective inhibitor of *Ca ²⁺/calmodulin-dependent protein phosphatase* (calcineurin), with an IC₅₀** of ~10 μM. Calcineurin autoinhibitory peptide TFA could protect neurons from excitatory neuronal death .

SWE101	Epoxide Hydrolase	Metabolic Disease
SWE101 (compound 22 b) is a potent soluble epoxide hydrolase (sEH)-P inhibitor with IC₅₀s of 4 μM and 2.8 μM for human and rat sEH-P, respectively. SWE101 does not inhibit neither hydrolase nor phosphatase activity of the mouse sEH .

Alexidine dihydrochloride	Fungal Apoptosis	Infection
Alexidine dihydrochloride is an anticancer agent that targets a mitochondrial tyrosine phosphatase, PTPMT1, in mammalian cells and causes mitochondrial apoptosis. Alexidine dihydrochloride has antifungal and antibiofilm activity against a diverse range of fungal pathogens .

Chrysophanol triglucoside	Phosphatase Glucosidase	Metabolic Disease
Chrysophanol triglucoside is an anthraquinone isolated from Cassia obtusifolia, inhibits *protein tyrosine phosphatases* 1B (PTP1B) and α-glucosidase with IC₅₀**s of 80.17 and 197.06 µM, respectively. Chrysophanol triglucoside has the potential for diabetes research .

Cryptosporioptide A	Phosphatase	Metabolic Disease
Cryptosporioptide A (Compound 3) is a pigment protein tyrosine phosphatase inhibitor derived from the insect-parasitic fungus Cordyceps gracilioides. Cryptosporioptide A inhibits PTP1B, SHP2, CDC25B, LAR and SHP1 enzymes with IC₅₀ of 7.3, 5.7, 7.6, >50, 4.9 μg/mL, respectively .

Phostriecin	Antibiotic Phosphatase	Infection Inflammation/Immunology Cancer
Phostriecin is an antitumor antibiotic produced by Streptomyces pulveraceus. Phostriecin is a strong inhibitor of type 2A (PP2A) and a weak inhibitor of type 1 (PP1) serine/threonine protein phosphatases with IC₅₀s of 3.2 nM and 131 μM, respectively. Phostriecin has the potential for the research of cancer .

Trimyristin	Cholinesterase (ChE) Phosphatase Endogenous Metabolite	Metabolic Disease
Trimyristin, an active molluscicidal component of Myristica fragrans Houtt, significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. IC₅₀s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively .

Icerguastat Sephin1; IFB-088	Phosphatase	Infection Inflammation/Immunology
Icerguastat (Sephin1), a derivative of Guanabenz lacking the α2-adrenergic activity, is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). Icerguastat inhibits eIF2α dephosphorylation, thereby prolonging the protective response. Anti-prion effect .

Piriprost potassium U 60257B	Leukotriene Receptor	Inflammation/Immunology
Piriprost (U-60,257B) potassium is an inhibitor of leukotriene synthesis. Piriprost potassium inhibits the release of both leukotriene and histamine with an IC₅₀ of 0.11 μM from isolated porcine lung cells. Piriprost potassium increases alkaline phosphatase (ALP) activity in cultured endometrial stromal cells .

Cat. No.	Product Name

HY-L081

Phosphatase Inhibitor Library

132 compounds

Protein phosphorylation is a key post-translational modification underlying the regulation of many cellular processes. Phosphatases and kinases contribute to the regulation of protein phosphorylation homeostasis in the cell. This reversible regulation of protein phosphorylation is critical for the proper control of a wide range of cellular activities, including cell cycle, proliferation and differentiation, metabolism, cell-cell interactions, etc.

Protein phosphatases have evolved in separate families that are structurally and mechanistically distinct. Based on substrate specificity and functional diversity, protein phosphatases are classified into two superfamilies: Protein serine/threonine phosphatases and Protein tyrosine phosphatases. Ser/Thr phosphatases are metalloenzymes belonging to two major gene families termed PPP (phosphoprotein phosphatase) and PPM (metal-dependent protein phosphatases), whereas protein tyrosine phosphatases (PTPs) belong to distinct classes of enzymes that utilize a phospho-cysteine enzyme intermediate as a part of their catalytic action.

MCE supplies a unique collection of 132 phosphatase inhibitors that mainly targeting protein tyrosine phosphatases (PTPs) and serine/threonine-specific protein phosphatases. MCE Phosphatase Inhibitor Library is a useful tool for phosphatase drug discovery and related research.

Cat. No.	Product Name	Type

HY-D0994

4-Methylumbelliferyl phosphate 4-MUP; MUP	Chromogenic Substrates
4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline *phosphatase* fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant .

HY-D1676

Thymolphthalein monophosphate disodium hydrate

Fluorescent Dyes/Probes

Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum .

HY-D1491

Fast Red Violet LB	Dyes
Fast Red Violet LB is a dye for staining tartrate resistant acid phosphatase (TRAP). Fast Red Violet LB can be used for alkaline phosphatase (ALP) activity staining .

HY-D1208

CDP-Star

Chromogenic Substrates

CDP-Star is a chemiluminescent substrate for alkaline phosphatase. CDP-Star can be used for enzyme-linked immunoassays .

HY-149835

TTX-P	Fluorescent Dyes/Probes
TTX-P is a fluorescent probe. TTX-P responds in situ to the overexpressed alkaline phosphatase (ALP) in liver, imaging of diabetic liver injury in the near-infrared second-window (NIR-II) region .

HY-D1739

DDAO phosphate diammonium	Fluorescent Dyes/Probes
DDAO phosphate diammonium is a fluorescent phosphatase substrate. DDAO phosphate diammonium has tunable excitation wavelength (600-650nm) and long emission wavelength (λem=656nm). DDAO phosphate diammonium can be used to detect the activity of different enzymes such as β-galactosidase, sulfatase, protein phosphatase 2A, carboxylesterase 2, human albumin and esterase.

HY-15928

PNPP disodium 1 Publications Verification Para-nitrophenyl phosphate disodium	Chromogenic Substrates
PNPP (Para-nitrophenyl phosphate) disodium is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays.

HY-15909

BCIP BCIP p-toluidine salt; X-phosphate p-toluidine salt	Chromogenic Substrates
BCIP(BCIP p-toluidine salt; X-phosphate p-toluidine salt) is an artificial chromogenic substrate used for the sensitive colorimetric detection of alkaline phosphatase activity.

HY-D1520

Naphthol AS-GR phosphate disodium	Fluorescent Dyes/Probes
Naphthol AS-GR phosphate disodium is substrates for acid and alkaline phosphatases. Naphthol AS-GR phosphate disodium has an intense green fluorescence used in histochemical studies .

HY-D0994A

4-Methylumbelliferyl phosphate disodium 4-MUP disodium; MUP disodium	Chromogenic Substrates
4-Methylumbelliferyl phosphate (4-MUP) disodium, an anionic organophosphate, is a acid and alkaline *phosphatase* fluorogenic substrate. 4-Methylumbelliferyl phosphate disodium is also a nerve agent simulant .

HY-15925

Nitro blue tetrazolium chloride 4 Publications Verification NBT	Chromogenic Substrates
Nitro blue tetrazolium chloride (NBT) is a substrate for dehydrogenases; is used with the alkaline phosphatase substrate 5-Bromo-4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures .

HY-D2204

SHP1-IN-1	Fluorescent Dyes/Probes
SHP1-IN-1 (compound 5p) is a fluorescent probe for the protein tyrosine phosphatase SHP1 containing the Src homology 2 domain. SHP1-IN-1 has SHP1 inhibitory activity, selectivity for Fe ³⁺ ions and good fluorescence properties. SHP1-IN-1 exhibits aggregation post-quenching (ACQ) effect, good interference immunity and low detection limit (5.55 μM) .

Cat. No.	Product Name	Type

HY-116022A

4-Nitrophenyl phosphate disodium hexahydrate 2 Publications Verification p-Nitrophenyl phosphate disodium hexahydrate	Biochemical Assay Reagents
4-Nitrophenyl phosphate (p-nitrophenyl phosphate) disodium hexahydrate is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. 4-Nitrophenyl phosphate disodium hexahydrate is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm .

HY-D0852

Sodium orthovanadate 5 Publications Verification	Biochemical Assay Reagents
Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue.

HY-19695

(-)-p-Bromotetramisole oxalate 1 Publications Verification L-p-Bromotetramisole oxalate; 6-Bromolevamisole oxalate	Biochemical Assay Reagents
(-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor.

HY-D1208

CDP-Star

Chromogenic Substrates

CDP-Star is a chemiluminescent substrate for alkaline phosphatase. CDP-Star can be used for enzyme-linked immunoassays .
HY-112832

Lumigen APS-5

Enzyme Substrates

Lumigen APS-5 is a substrate of alkaline phosphatase (ALP). Lumigen APS-5 can be used to assess the activity of alkaline phosphatase (ALP) .

HY-P2844

Polynucleotide kinase	Biochemical Assay Reagents
Polynucleotide Kinase is a DNA repair enzyme. Polynucleotide Kinase possesses both a 5’-kinase activity that catalyzes the transfer of phosphate from ATP to a 5’-hydroxyl (OH) terminus and also a 3’-phosphatase activity that converts 3’-phosphate termini to 3’-OH termini .

HY-15906

AMPPD

Lumi-Phos Plus; Lumigen PPD; PPD
Enzyme Substrates

AMPPD, a 1,2-dioxo-cyclohexane derivative, is a biochemistry ultrasensitive alkaline phosphatase substrate.

HY-130767

Naphthol AS-TR phosphate

Biochemical Assay Reagents

Naphthol AS-TR Phosphate is a water-soluble dye commonly used as an enzyme substrate in various biochemical assays to detect alkaline phosphatase activity. Naphthol AS-TR Phosphate has unique chemical properties that allow it to be hydrolyzed by alkaline phosphatase to form a colored product that can be detected spectrophotometrically. This makes it a useful tool for monitoring enzyme activity in biological samples such as serum or urine.

HY-W045537

5-Bromo-4-chloro-1H-indol-3-yl phosphate sodium

Biochemical Assay Reagents

Sodium 5-bromo-4-chloro-1H-indol-3-yl phosphate is commonly used as a substrate for phosphatase assays in biochemistry and molecular biology. This compound is converted by phosphatases to a yellow compound that can be easily measured spectrophotometrically or fluorometrically. Furthermore, it has been used as a useful reagent in enzyme-catalyzed reactions and a tool for studying signal transduction pathways.

HY-W250153

Adenosine 3'-phosphate 5'-phosphosulfate lithium	Biochemical Assay Reagents
Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .

HY-W250153A

Adenosine 3'-phosphate 5'-phosphosulfate lithium, hydrate	Biochemical Assay Reagents
Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .

HY-103701B

L-Ascorbic acid 2-phosphate magnesium hydrate

2-Phospho-L-ascorbic acid magnesium hydrate

Biochemical Assay Reagents

L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) magnesium hydrate is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-ascorbic acid 2-phosphate magnesium hydrate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate magnesium hydrate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation .

Cat. No.	Product Name	Target	Research Area

HY-P2040

Nodularin

Peptides Cancer

Nodularin is a potent hepatotoxin, tumor promoter, and protein phosphatase inhibitor .

HY-P5363

PAP 248–286 Prostatic Acid Phosphatase(248-286)	HIV	Others
PAP 248–286 is a biological active peptide. (Prostatic Acid Phosphatase (248-286), PAP (248-286) peptide is a semen-derived enhancer of viral infection (SEVI) factor found in semen. This peptide greatly increases HIV infection through enhanced virion attachment to target cells.)

HY-P5996

MCA-Gly-Asp-Ala-Glu-pTyr-Ala-Ala-Lys(DNP)-Arg-NH2	Peptides	Others
MCA-Gly-Asp-Ala-Glu-pTyr-Ala-Ala-Lys(DNP)-Arg-NH2 is a protein tyrosine phosphatase fluorogenic substrate that can be detected at 393 nm (with excitation at 325 nm) .

HY-W141781

Cysteamine S-phosphate sodium Cystaphos sodium	Peptides	Metabolic Disease
Cysteamine S-phosphate (Cystaphos) sodium can be hydroIyzed to Cysteamine by human alkaline phosphatases. Cysteamine is an orally active agent for the research of nephropathic cystinosis and an antioxidant .

HY-P0320A

EGF Receptor Substrate 2 (Phospho-Tyr5) (TFA)	Phosphatase Biochemical Assay Reagents	Others
EGF Receptor Substrate 2 (Phospho-Tyr5) acetate, a biologically active peptide, is a tyrosine phosphate substrate. EGF Receptor Substrate 2 (Phospho-Tyr5) acetate can be used to detect protein tyrosine phosphatases activity .

HY-P0320B

EGF Receptor Substrate 2 (Phospho-Tyr5) (acetate)	Phosphatase Biochemical Assay Reagents	Others
EGF Receptor Substrate 2 (Phospho-Tyr5) acetate, a biologically active peptide, is a tyrosine phosphate substrate. EGF Receptor Substrate 2 (Phospho-Tyr5) acetate can be used to detect protein tyrosine phosphatases activity .

HY-P1247

Calcineurin autoinhibitory peptide	Phosphatase	Neurological Disease
Calcineurin autoinhibitory peptide is a selective inhibitor of *Ca ²⁺/calmodulin-dependent protein phosphatase* (calcineurin), with an IC₅₀** of ~10 μM. Calcineurin autoinhibitory peptide could protect neurons from excitatory neuronal death .

HY-P1247A

Calcineurin autoinhibitory peptide TFA	Phosphatase	Neurological Disease
Calcineurin autoinhibitory peptide TFA is a selective inhibitor of *Ca ²⁺/calmodulin-dependent protein phosphatase* (calcineurin), with an IC₅₀** of ~10 μM. Calcineurin autoinhibitory peptide TFA could protect neurons from excitatory neuronal death .

HY-W007599

(S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid	Peptides	Cancer
(S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid is a polypeptide derivative, can be used to synthesis multifunctional amphiphilic peptide dendrimer, as a nonviral gene vectors, realizes the method in cancer research. (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid also involves in the synthesis of an organic substance that increases the luminescence intensity of alkaline phosphatase substrates .

HY-P5441

KRpTIRR

Peptides Others

KRpTIRR is a biological active peptide. (Phosphatase substrate.)
HY-P5447

RRLIEDAEpYAARG

Peptides Others

RRLIEDAEpYAARG is a biological active peptide. (Phosphatase substrate.)

HY-P2844

Polynucleotide kinase	DNA/RNA Synthesis	Metabolic Disease
Polynucleotide Kinase is a DNA repair enzyme. Polynucleotide Kinase possesses both a 5’-kinase activity that catalyzes the transfer of phosphate from ATP to a 5’-hydroxyl (OH) terminus and also a 3’-phosphatase activity that converts 3’-phosphate termini to 3’-OH termini .

HY-P5489

IGRP(206-214)	Peptides	Others
IGRP(206-214) is a biological active peptide. (This peptide corresponds to residues 206–214 of murine islet-specific glucose-6-phosphatase catalytic subunit–related protein (IGRP). This peptide is T cells specific for proinsulin and IGRP induces diabetes in non-obese diabetic (NOD) mice.)

HY-P0217

Microcystin-RR Cyanoviridin RR	Phosphatase Apoptosis	Metabolic Disease
Microcystin-RR (Cyanoviridin RR) is a potent and orally active protein phosphatase inhibitor. Microcystin-RR induces Apoptosis and ER stress in mice liver .

HY-P0219

Microcystin-LA	Phosphatase	Cancer
Microcystin LA, a natural toxin, exerts its cytotoxic exects by inhibiting the serine-threonine protein phosphatases PP1 and PP2A with IC₅₀s of 0.3 and 0.3 nM, respectively .

HY-P4835

pTH (2-34) (human)	Peptides	Others
pTH (2-34) (human) (80 μg/kg) slightly increases serum osteocalcin levels and alkaline phosphatase activity of bone extract (markers of bone formation) in mice. pTH (2-34) is not as effective as pTH (1-34) .

HY-P0320

EGF Receptor Substrate 2 (Phospho-Tyr5)	Phosphatase	Others
EGF Receptor Substrate 2 (Phospho-Tyr5) acetate, a biologically active peptide, is a tyrosine phosphate substrate. EGF Receptor Substrate 2 (Phospho-Tyr5) acetate can be used to detect protein tyrosine phosphatases activity .

HY-P1039

R18 PHCVPRDLSWLDLEANMCLP	Raf	Cancer
R18 is a peptide antagonists of 14-3-3, with a K_D of 70-90 nM. R18 efficiently blocks the binding of 14-3-3 to the kinase Raf-1, a physiological ligand of 14-3-3, and effectively abolished the protective role of 14-3-3 against phosphatase-induced inactivation of Raf-1 .

HY-P3940

Ac-MBP (4-14) Peptide	PKC	Others
Ac-MBP (4-14) Peptide is an acetylated MBP (4-14) peptide. MBP (4-14) Peptide is a very selective (protein kinase C) PKC substrate. Ac-MBP (4-14) Peptide can be used for PKC assay in extracts without prior purification to eliminate interfering protein kinases or phosphatases .

HY-P1039A

R18 TFA PHCVPRDLSWLDLEANMCLP TFA	Raf	Cancer
R18 TFA is a peptide antagonists of 14-3-3, with a K_D of 70-90 nM. R18 efficiently blocks the binding of 14-3-3 to the kinase Raf-1, a physiological ligand of 14-3-3, and effectively abolished the protective role of 14-3-3 against phosphatase-induced inactivation of Raf-1 .

HY-P4823

pTH (1-37) (human)	Thyroid Hormone Receptor	Metabolic Disease
pTH (1-37) (human) is a fragment of parathyroid hormone (PTH). pTH (1-37) (human) induces the cAMP formation and increases alkaline phosphatase activity. pTH (1-37) (human) increases growth, bone calcium content, and bone mineral density (BMD) in uremic animals. pTH (1-37) (human) has the potential for the research of osteoporosis .

HY-P3355

p-fin4	iGluR	Neurological Disease
p-fin4 is a peptide inhibitor of STEP Phosphatase-GluA2 AMPA receptor interaction with a Ki of 0.4 μM. p-fin4 restores the memory deficits and displays anxiolytic and antidepressant effects in a scopolamine-treated rat model. p-fin4 is a promising lead compound for novel cognitive enhancers and/or behavioral modulators .

HY-P3354

p3Ysh-3	iGluR	Neurological Disease
p3Ysh-3 is a peptide inhibitor of STEP Phosphatase-GluA2 AMPA receptor interaction with a Ki of 1.09 μM. p3Ysh-3 restores the memory deficits and displays anxiolytic and antidepressant effects in a scopolamine-treated rat model. p3Ysh-3 is a promising lead compound for novel cognitive enhancers and/or behavioral modulators .

Cat. No.	Product Name

HY-K0022

Phosphatase Inhibitor Cocktail II 315+ Cited Publications
Phosphatase Inhibitor Cocktail II effectively inhibits acid and alkaline phosphatases as well as protein tyrosine phosphatases(PTPs).

HY-K0021

Phosphatase Inhibitor Cocktail I Maximum Cited Publications 351 Publications Verification
Phosphatase Inhibitor Cocktail I effectively inhibits alkaline phosphatases and serine/threonine protein phosphatases such as PP1 and PP2A.

HY-K0023

Phosphatase Inhibitor Cocktail III

205+ Cited Publications

Phosphatase Inhibitor Cocktail III effectively inhibits serine/threonine and alkaline phosphatases.

HY-K0013

*Protease and Phosphatase* Inhibitor Cocktail (EDTA-Free, 10× in ddH2O)** 40+ Cited Publications
MCE Protease and Phosphatase Inhibitor Cocktail (EDTA-Free, 10× in ddH2O) protects protein from degradation by endogenous proteases released during protein extraction and purification.

Recombinant Proteins Recommended:

Phosphatase

Species:	Human (72) Mouse (17) Rat (2) Cynomolgus (1)
Tag:	GFP (1) His (78) SUMO (2) Tag Free (5) Avi (1) Myc (1) GST (10) MBP (1) Fc (5) Flag (1)
Source:	HEK293 (44) P. pastoris (3) Sf9 insect cells (13) E. coli (33)

Cat. No.	Compare	Product Name	Species	Source

HY-P71854

	MINPP1 Protein, Human (P.pastoris, His) MINPP2; MIPP; Multiple inositol polyphosphate histidine Phosphatase, 1; Multiple inositol polyphosphate Phosphatase 1; multiple inositol polyphosphate Phosphatase 2	Human	P. pastoris
	MINPP1 Protein, a dual-function phosphatase, regulates inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6) levels through phosphoinositide 5- and phosphoinositide 6-phosphatase activity. It also acts as a 2,3-bisphosphoglycerate 3-phosphatase, crucial for bone development and chondrocyte transition. By controlling intracellular inositol polyphosphates, MINPP1 potentially influences cation homeostasis, impacting neural cell signaling through free cation availability. MINPP1 Protein, Human (P.pastoris, His) is the recombinant human-derived MINPP1 protein, expressed by P. pastoris, with N-His labeled tag. The total length of MINPP1 Protein, Human (P.pastoris, His) is 457 a.a., with molecular weight of ~55.3 kDa.

HY-P71768

	*PLP phosphatase* Protein, Mouse (P.pastoris, His)** Pdxp; Cin; Plp; Plpp; Pyridoxal phosphate Phosphatase; PLP Phosphatase; Chronophin	Mouse	P. pastoris
	The PLP phosphatase protein plays a dual role as a pyridoxal phosphate (PLP) phosphatase and a protein serine phosphatase. Its enzymatic activity in vitamin B6 metabolism involves the dephosphorylation of PLP, PNP and PMP. PLP phosphatase Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived PLP phosphatase protein, expressed by P. pastoris , with N-His labeled tag. The total length of PLP phosphatase Protein, Mouse (P.pastoris, His) is 292 a.a., with molecular weight of ~33.5 kDa.

HY-P71150

	DUSP3 Protein, Human (His) Dual specificity protein Phosphatase 3; DUSP3; Dual specificity protein Phosphatase VHR; Vaccinia H1-related Phosphatase; VHR	Human	E. coli
	DUSP3, a dual-specificity phosphatase, preferentially dephosphorylates phosphotyrosines. Its main function involves inactivating ERK1 and ERK2, thereby modulating associated cellular signaling pathways. DUSP3 Protein, Human (His) is the recombinant human-derived DUSP3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of DUSP3 Protein, Human (His) is 184 a.a., with molecular weight of 18-22 kDa.

HY-P7487

	*Alkaline Phosphatase/ALPP Protein, Human (HEK293, His)* rHuAlkaline Phosphatase, His; ALPP; PLAP; ALP; AKP2; Alkaline Phosphatase	Human	HEK293
	ALPP Protein, Human (HEK293, His) is a ubiquitous membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at basic pH values.

HY-P70937

	MINPP1 Protein, Human (HEK293, His) Multiple Inositol Polyphosphate Phosphatase 1; 2,3-Bisphosphoglycerate 3-Phosphatase; 2,3-BPG Phosphatase; Inositol (1,3,4,5)-Tetrakisphosphate 3-Phosphatase; Ins(1,3,4,5)P(4) 3-Phosphatase; MINPP1; MIPP	Human	HEK293
	MINPP1 Protein, a dual-function phosphatase, regulates inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6) levels through phosphoinositide 5- and phosphoinositide 6-phosphatase activity. It also acts as a 2,3-bisphosphoglycerate 3-phosphatase, crucial for bone development and chondrocyte transition. By controlling intracellular inositol polyphosphates, MINPP1 potentially influences cation homeostasis, impacting neural cell signaling through free cation availability. MINPP1 Protein, Human (HEK293, His) is the recombinant human-derived MINPP1 protein, expressed by HEK293, with C-6*His labeled tag. The total length of MINPP1 Protein, Human (HEK293, His) is 457 a.a., with molecular weight of ~56.0 kDa.

HY-P70327A

	LMW-PTP/ACP1 Protein, Human (C-His) rHuLow molecular weight phosphotyrosine protein Phosphatase/LMW-PTP, His; Low Molecular Weight Phosphotyrosine Protein Phosphatase; LMW-PTP; LMW-PTPase; Adipocyte Acid Phosphatase; Low Molecular Weight Cytosolic Acid Phosphatase; Red Cell Acid Phosphatase 1; ACP1	Human	E. coli
	LMW-PTP/ACP1, a phosphatase, acts on tyrosine phosphorylated proteins, low-molecular-weight aryl phosphates, and natural and synthetic acyl phosphates. Notably, there are substrate specificity differences between isoform 1 and isoform 2, with isoform 2 lacking phosphatase activity. LMW-PTP/ACP1 Protein, Human (C-His) is the recombinant human-derived LMW-PTP/ACP1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of LMW-PTP/ACP1 Protein, Human (C-His) is 157 a.a., with molecular weight of ~18.0 kDa.

HY-P7487A

	*Alkaline Phosphatase/ALPP Protein, Human (HEK293, C-His)* rHuAlkaline Phosphatase, His; ALPP; PLAP; ALP; AKP2; Alkaline Phosphatase	Human	HEK293
	Alkaline Phosphatase/ALPP Proteinas, an enzyme, effectively hydrolyzes various phosphate compounds. Alkaline Phosphatase/ALPP Protein, Human (HEK293, C-His) is the recombinant human-derived Alkaline Phosphatase/ALPP protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Alkaline Phosphatase/ALPP Protein, Human (HEK293, C-His) is 484 a.a., with molecular weight of approximately 62.5 kDa.

HY-P700950

	*Alkaline Phosphatase/ALPG Protein, Mouse (HEK293, His)* Alkaline Phosphatase; Alkaline Phosphatase, placental-like; EAP; Alpg; Akp5; Alppl2	Mouse	HEK293
	Alkaline Phosphatase/ALPG Proteinas, an enzyme, effectively hydrolyzes various phosphate compounds. Alkaline Phosphatase/ALPG Protein, Mouse (HEK293, His) is the recombinant mouse-derived Alkaline Phosphatase/ALPG protein, expressed by HEK293, with C-His labeled tag. The total length of Alkaline Phosphatase/ALPG Protein, Mouse (HEK293, His) is 484 a.a., with molecular weight of 55-70 kDa.

HY-P7880

	*Alkaline Phosphatase/ALPL Protein, Human (HEK293, His)* rHuAlkaline Phosphatase, tissue-nonspecific isozyme/ALPL, His; Alkaline Phosphatase; Tissue-Nonspecific Isozyme; AP-TNAP; TNSALP; Alkaline Phosphatase Liver/Bone/Kidney Isozyme; ALPL	Human	HEK293
	Alkaline Phosphatase/ALPL Protein, Human (HEK 293, His) is a cell-surface homodimeric phosphohydrolase that is richly expressed in the skeleton, liver, kidney and developing teeth.

HY-P76713

	ACPL2 Protein, Human (HEK293, His) 2-phosphoxylose Phosphatase 1; Acid Phosphatase-like protein 2; PXYLP1; HEL124	Human	HEK293
	The ACPL2 protein plays a critical role in the regulation of glycosaminoglycan (GAG) chains by catalyzing the 2-O-dephosphorylation of xylose in proteoglycans. This step is critical for the synthesis of sulfated GAGs, including heparan sulfate and chondroitin sulfate. ACPL2 Protein, Human (HEK293, His) is the recombinant human-derived ACPL2 protein, expressed by HEK293 , with C-His labeled tag. The total length of ACPL2 Protein, Human (HEK293, His) is 480 a.a., with molecular weight of ~50 kDa.

HY-P700952

	*Alkaline Phosphatase/ALPG Protein, Human (HEK293, His)* Alkaline Phosphatase; ALP-1; Alkaline Phosphatase, placental-like; GCAP; PLAP-like; ALPG; ALPPL; ALPPL2	Human	HEK293
	The Alkaline Phosphatase/ALPG protein, an enzyme, hydrolyzes phosphate compounds, breaking down various molecules. It acts as an alkaline phosphatase, cleaving phosphate esters and rendering molecules inactive. This versatile enzyme is vital in processes like bone mineralization, cellular signaling, and metabolism. Alkaline Phosphatase/ALPG Protein, Human (HEK293, His) is the recombinant human-derived Alkaline Phosphatase/ALPG protein, expressed by HEK293, with C-His labeled tag. The total length of Alkaline Phosphatase/ALPG Protein, Human (HEK293, His) is 484 a.a., with molecular weight of 58-68 kDa.

HY-P702581

Alkaline Phosphatase/ALPG Protein, Rat (HEK293, His)

Alkaline Phosphatase; ALP-1; Alkaline Phosphatase, placental-like; GCAP; PLAP-like; ALPG; ALPPL; ALPPL2
Rat HEK293

HY-P72822

	ALPI Protein, Human (HEK293, His) Intestinal-type alkaline Phosphatase; IAP; ALPI; Alkaline Phosphatase	Human	HEK293
	ALPI Proteinas, an alkaline phosphatase, effectively hydrolyzes diverse phosphate compounds. ALPI Protein, Human (HEK293, His) is the recombinant human-derived ALPI protein, expressed by HEK293 , with C-His labeled tag. The total length of ALPI Protein, Human (HEK293, His) is 484 a.a., with molecular weight of ~70-80 kDa.

HY-P72821

	ALPI Protein, Human (HEK293, Fc) Intestinal-type alkaline Phosphatase; IAP; ALPI; Alkaline Phosphatase	Human	HEK293
	ALPI Proteinas, an alkaline phosphatase, effectively hydrolyzes diverse phosphate compounds. ALPI Protein, Human (HEK293, Fc) is the recombinant human-derived ALPI protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ALPI Protein, Human (HEK293, Fc) is 503 a.a., with molecular weight of 90-95 kDa.

HY-P74415

	*Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, His)* Alkaline Phosphatase; AP-TNAP; TNSALP; ALPL	Mouse	HEK293
	Alkaline Phosphatase/ALPL Protein is a preproprotein that is proteolytically cleaved to yield a signal peptide and a proproptein that is subsequently processed to generate the active mature peptide. ALPL is also a membrane-bound glycosylated enzyme that catalyzes the hydrolysis of phosphate esters at alkaline pH. Mice that lack ALPL show symptoms of osteomalacia, softening of the bones. Moreover, ALPL stimulates mineralization mainly through modulation of the balance between inorganic phosphate (Pi) and inorganic pyrophosphate (PPi) and also has a role in cardiovascular remodelling. Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, His) is the recombinant mouse-derived Alkaline Phosphatase/ALPL protein, expressed by HEK293 , with C-His, C-8*His labeled tag. The total length of Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, His) is 502 a.a., with molecular weight of ~55 kDa.

HY-P74416

	*Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, Fc)* Alkaline Phosphatase; AP-TNAP; TNSALP; ALPL	Mouse	HEK293
	Alkaline Phosphatase/ALPL Protein is a preproprotein that is proteolytically cleaved to yield a signal peptide and a proproptein that is subsequently processed to generate the active mature peptide. ALPL is also a membrane-bound glycosylated enzyme that catalyzes the hydrolysis of phosphate esters at alkaline pH. Mice that lack ALPL show symptoms of osteomalacia, softening of the bones. Moreover, ALPL stimulates mineralization mainly through modulation of the balance between inorganic phosphate (Pi) and inorganic pyrophosphate (PPi) and also has a role in cardiovascular remodelling. Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Alkaline Phosphatase/ALPL protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, Fc) is 502 a.a., with molecular weight of ~80.3 kDa.

HY-P700395

	ALPI Protein, Rat (HEK293, His) Intestinal-type alkaline Phosphatase; IAP; ALPI; Alkaline Phosphatase	Rat	HEK293
	The ALPI protein, an alkaline phosphatase enzyme, hydrolyzes phosphate compounds, demonstrating enzymatic activity in breaking down different phosphate molecules. ALPI Protein, Rat (HEK293, His) is the recombinant rat-derived ALPI protein, expressed by HEK293, with N-10*His labeled tag. The total length of ALPI Protein, Rat (HEK293, His) is 491 a.a., with molecular weight of 55.9 kDa.

HY-P700949

	*Alkaline Phosphatase/ALPP Protein, Cynomolgus (HEK293, His)* Alkaline Phosphatase; PLAP-1; ALPP; PLAP	Cynomolgus	HEK293
	Alkaline Phosphatase (ALPP) is an ubiquitous membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at basic pH values. Zinc and magnesium are essential cofactors of ALPP. ALPP down-regulates the secretory activities of the intrahepatic biliary epithelium. Alkaline Phosphatase/ALPP Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Alkaline Phosphatase/ALPP protein, expressed by HEK293 , with C-His labeled tag. The total length of Alkaline Phosphatase/ALPP Protein, Cynomolgus (HEK293, His) is 483 a.a., with molecular weight of 57-67 kDa.

HY-P71769

	PHPT1 Protein, Human (P.pastoris, His) 14kDa phosphohistidine Phosphatase; CGI 202; HSPC141; Phosphohistidine Phosphatase 1; PHP14	Human	P. pastoris
	The PHPT1 protein acts as a phosphohistidine phosphatase, catalyzing the dephosphorylation of phosphohistidine residues. This unique enzymatic activity makes PHPT1 a regulator of histidine phosphorylation events, suggesting that it is involved in signaling pathways or cellular processes that are critical for phosphohistidine modification. PHPT1 Protein, Human (P.pastoris, His) is the recombinant human-derived PHPT1 protein, expressed by P. pastoris , with N-His labeled tag. The total length of PHPT1 Protein, Human (P.pastoris, His) is 125 a.a., with molecular weight of ~15.8 kDa.

HY-P700394

	ALPI Protein, Human (HEK293, N-His) Intestinal-type alkaline Phosphatase; IAP; ALPI; Alkaline Phosphatase	Human	HEK293
	ALPI Proteinas, an alkaline phosphatase, effectively hydrolyzes diverse phosphate compounds. ALPI Protein, Human (HEK293, N-His) is the recombinant human-derived ALPI protein, expressed by HEK293, with N-10*His labeled tag. The total length of ALPI Protein, Human (HEK293, N-His) is 484 a.a., with molecular weight of 55.2 kDa.

HY-P700951

	*Alkaline Phosphatase/ALPG Protein, Human (Biotinylated, HEK293, His-Avi)* Alkaline Phosphatase; ALP-1; Alkaline Phosphatase, placental-like; GCAP; PLAP-like; ALPG; ALPPL; ALPPL2	Human	HEK293
	The Alkaline Phosphatase/ALPG protein, an enzyme, hydrolyzes phosphate compounds, breaking down various molecules. It acts as an alkaline phosphatase, cleaving phosphate esters and rendering molecules inactive. This versatile enzyme is vital in processes like bone mineralization, cellular signaling, and metabolism. Alkaline Phosphatase/ALPG Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived Alkaline Phosphatase/ALPG protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of Alkaline Phosphatase/ALPG Protein, Human (Biotinylated, HEK293, His-Avi) is 484 a.a., with molecular weight of 56-70 kDa.

HY-P71241

	PSP Protein, Human (His) Phosphoserine Phosphatase; PSP; PSPase; L-3-Phosphoserine Phosphatase; O-Phosphoserine Phosphohydrolase; PSPH	Human	E. coli
	PSP protein catalyzes the final irreversible step in carbohydrate biosynthesis of L-serine through dephosphorylation of O-phospho-L-serine. PSP Protein, Human (His) is the recombinant human-derived PSP protein, expressed by E. coli , with C-6*His labeled tag. The total length of PSP Protein, Human (His) is 225 a.a., with molecular weight of 25-30 kDa.

HY-P74430

	*ACPP/Prostatic Acid Phosphatase* Protein, Mouse (HEK293, His)** ACP-3; ACPP; Prostatic Acid Phosphatase; PAPf39; PAP	Mouse	HEK293
	The acid prostatic phosphatase (ACPP) protein, encapsulated in virus-like particles (VLPs), is an acid tyrosine phosphatase that skillfully dephosphorylates a variety of substrates. ACPP-VLP possesses lipid phosphatase activity and inactivates lysophosphatidic acid. ACPP/Prostatic Acid Phosphatase Protein, Mouse (HEK293, His) is the recombinant mouse-derived ACPP/Prostatic Acid Phosphatase protein, expressed by HEK293 , with C-His labeled tag. The total length of ACPP/Prostatic Acid Phosphatase Protein, Mouse (HEK293, His) is 350 a.a., with molecular weight of 44-55 kDa.

HY-P76556

	PTPMT1 Protein, Human (His) PhosphatidylglyceroPhosphatase and protein-tyrosine Phosphatase 1; PTPMT1; MOSP; PLIP	Human	E. coli
	The PTPMT1 protein is a lipid phosphatase that critically regulates cellular lipid metabolism by dephosphorylating phosphatidylglycerolphosphate (PGP) to form phosphatidylglycerol (PG). This step is critical for the biosynthesis of cardiolipin, a key mitochondrial phospholipid that regulates membrane integrity and mitochondrial activity. PTPMT1 Protein, Human (His) is the recombinant human-derived PTPMT1 protein, expressed by E. coli , with N-His labeled tag. The total length of PTPMT1 Protein, Human (His) is 174 a.a., with molecular weight of ~22 kDa.

HY-P700619

	*Prostatic acid Phosphatase/ACPP Protein, Human (HEK293, GFP-His)* ACP-3; ACPP; Prostatic Acid Phosphatase; PAPf39; PAP	Human	HEK293
	Prostatic acid phosphatase (ACPP) operates as a versatile tyrosine phosphatase under acidic conditions (pH 4-6), dephosphorylating various substrates, including orthophosphate monoesters. With lipid phosphatase activity, ACPP inactivates lysophosphatidic acid in seminal plasma. In prostate cancer, it acts as a tumor suppressor by dephosphorylating ERBB2, deactivating MAPK signaling, and controlling cancer-related processes. ACPP also exhibits ecto-5'-nucleotidase activity in dorsal root ganglion neurons, suggesting a role in pain modulation by generating adenosine from AMP. Prostatic acid Phosphatase/ACPP Protein, Human (HEK293, GFP-His) is the recombinant human-derived Prostatic acid Phosphatase/ACPP protein, expressed by HEK293, with C-His, GFP labeled tag. The total length of Prostatic acid Phosphatase/ACPP Protein, Human (HEK293, GFP-His) is 350 a.a., with molecular weight of 70.6 kDa.

HY-P701970

	PTPRG Protein, Human PTPRG; Receptor-type tyrosine-protein Phosphatase gamma; Protein-tyrosine Phosphatase gamma; R-PTP-gamma	Human	E. coli
	PTPRG protein, also known as G-type protein tyrosine phosphatase receptor, is characterized by its tyrosine phosphatase activity. As a member of the protein tyrosine phosphatase (PTP) family, PTPRG is involved in the dephosphorylation of tyrosine residues in target proteins. PTPRG Protein, Human is the recombinant human-derived PTPRG protein, expressed by E. coli , with tag free. The total length of PTPRG Protein, Human is 311 a.a., .

HY-P71022

	PP1MG Protein, Human (His) Protein Phosphatase 1G; Protein Phosphatase 1C; Protein Phosphatase 2C Isoform Gamma; PP2C-Gamma; Protein Phosphatase Magnesium-Dependent 1 Gamma; PPM1G; PPM1C	Human	E. coli
	PP1MG Protein, a member of PPM family of serine/threonine phosphatases, has an important role in controlling cell cycle progression. PP1MG Proteinregulates the phosphorylation of SRSF3 in hepatocellular carcinoma (HCC) and contributes to the proliferation, invasion, and metastasis of HCC. PP1MG Protein forms a distinct holoenzyme complex with the PP2A regulatory subunit B56δ. B56δ‐PPM1G dephosphorylates α‐catenin at serine 641, which is necessary for the appropriate assembly of adherens junctions and the prevention of aberrant cell migration. PP1MG Protein, Human (His) is the recombinant human-derived PP1MG protein, expressed by E. coli , with C-6*His labeled tag. The total length of PP1MG Protein, Human (His) is 230 a.a., with molecular weight of ~30.0 kDa.

HY-P71141

	SHP-1 Protein, Human (His) Tyrosine-Protein Phosphatase Non-Receptor Type 6; Hematopoietic Cell Protein-Tyrosine Phosphatase; Protein-Tyrosine Phosphatase 1C; PTP-1C; Protein-Tyrosine Phosphatase SHP-1; SH-PTP1; PTPN6; HCP; PTP1C	Human	E. coli
	SHP-1 Protein modulates signaling from tyrosine-phosphorylated cell surface receptors, including KIT and EGFR. It enhances the inhibition of mast cell activation via the Lilrb4a receptor. The SH2 regions interact with cellular components to regulate its phosphatase activity. In collaboration with MTUS1, it induces UBE2V2 expression upon angiotensin II stimulation. SHP-1 plays a crucial role in hematopoiesis. SHP-1 Protein, Human (His) is the recombinant human-derived SHP-1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of SHP-1 Protein, Human (His) is 299 a.a., with molecular weight of ~33.0 kDa.

HY-P71227

	PPM1A Protein, Human (His) Protein Phosphatase 1A; Protein Phosphatase 2C Isoform Alpha; PP2C-Alpha; Protein Phosphatase IA; PPM1A; PPPM1A	Human	E. coli
	PPM1A is a multifunctional enzyme that negatively regulates multiple signaling pathways. It significantly attenuates TGF-β signaling by dephosphorylating SMAD2 and SMAD3, leading to their dissociation from SMAD4, nuclear export, and signal termination. PPM1A Protein, Human (His) is the recombinant human-derived PPM1A protein, expressed by E. coli , with C-6*His labeled tag. The total length of PPM1A Protein, Human (His) is 381 a.a., with molecular weight of ~45.0 kDa.

HY-P701971

	PTPRG Protein, Human (His) PTPRG; Receptor-type tyrosine-protein Phosphatase gamma; Protein-tyrosine Phosphatase gamma; R-PTP-gamma	Human	E. coli
	PTPRG protein, also known as G-type protein tyrosine phosphatase receptor, is characterized by its tyrosine phosphatase activity. As a member of the protein tyrosine phosphatase (PTP) family, PTPRG is involved in the dephosphorylation of tyrosine residues in target proteins. PTPRG Protein, Human (His) is the recombinant human-derived PTPRG protein, expressed by E. coli , with N-6*His labeled tag. The total length of PTPRG Protein, Human (His) is 311 a.a., .

HY-P7817

	*Prostatic acid phosphatase/ACPP Protein, Human (354a.a, HEK293, His, solution)* rHuProstatic acid Phosphatase/ACPP, His; Prostatic Acid Phosphatase; PAP; 5'-Nucleotidase; 5'-NT, Ecto-5'-Nucleotidase; Thiamine MonoPhosphatase; TMPase; ACPP	Human	HEK293
	PPAP protein, a nonspecific tyrosine phosphatase, has anticancer and antiproliferative activities. The PPAP protein dephosphorylates a variety of substrates under acidic conditions (pH 4-6), resulting in the inactivation of lysophosphatidic acid in seminal plasma. The PPAP protein is also a common biomarker for prostate cancer and can inhibit tumor development. Prostatic acid phosphatase/ACPP Protein, Human (354a.a, HEK293, His, solution) is the recombinant human-derived Prostatic acid phosphatase/ACPP protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Prostatic acid phosphatase/ACPP Protein, Human (354a.a, HEK293, His, solution) is 354 a.a., with molecular weight of ~50.0 kDa.

HY-P71579

	*TFIIF-associating CTD phosphatase* Protein, Mouse (Myc, His)** Ctdp1; Fcp1; RNA polymerase II subunit A C-terminal domain Phosphatase; EC 3.1.3.16; TFIIF-associating CTD Phosphatase	Mouse	E. coli
	The TFIIF-related CTD phosphatase protein plays a key role in promoting RNA polymerase II activity by dephosphorylating "Ser-2" and "Ser-5" residues. This enhances the function of RNA polymerase II, allowing the protein to participate in the transcription process. TFIIF-associating CTD phosphatase Protein, Mouse (Myc, His) is the recombinant mouse-derived TFIIF-associating CTD phosphatase protein, expressed by E. coli , with N-His, C-Myc labeled tag. The total length of TFIIF-associating CTD phosphatase Protein, Mouse (Myc, His) is 164 a.a., with molecular weight of ~24.0 kDa.

HY-P76307

	DUSP14 Protein, Human (His-MBP) Dual specificity protein Phosphatase 14; MKP-L; MKP-6; DUSP14	Human	E. coli
	DUSP14 protein can inactivate MAP kinase and dephosphorylate ERK, JNK and p38 MAP kinase. Its negative regulation extends to TCR signaling, where DUSP14 dephosphorylates the MAP3K7 adapter TAB1, resulting in inactivation. DUSP14 Protein, Human (His-MBP) is the recombinant human-derived DUSP14 protein, expressed by E. coli , with N-His, N-MBP labeled tag. The total length of DUSP14 Protein, Human (His-MBP) is 191 a.a., with molecular weight of ~60 KDa.

HY-P70870

	MDP1 Protein, Human (HEK293, His) Magnesium-dependent Phosphatase 1; MDP-1; EC=3.1.3.48;	Human	HEK293
	MDP1 Protein, a magnesium-dependent phosphatase, potentially functions as a tyrosine phosphatase. MDP1 Protein, Human (HEK293, His) is the recombinant human-derived MDP1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of MDP1 Protein, Human (HEK293, His) is 176 a.a., with molecular weight of ~18.0 kDa.

HY-P700620

	*Prostatic acid Phosphatase/ACPP Protein-VLP, Human (386a.a, HEK293, His)* ACP-3; ACPP; Prostatic Acid Phosphatase; PAPf39; PAP	Human	HEK293
	Prostatic acid phosphatase (ACPP) operates as a versatile tyrosine phosphatase under acidic conditions (pH 4-6), dephosphorylating various substrates, including orthophosphate monoesters. With lipid phosphatase activity, ACPP inactivates lysophosphatidic acid in seminal plasma. In prostate cancer, it acts as a tumor suppressor by dephosphorylating ERBB2, deactivating MAPK signaling, and controlling cancer-related processes. ACPP also exhibits ecto-5'-nucleotidase activity in dorsal root ganglion neurons, suggesting a role in pain modulation by generating adenosine from AMP. Prostatic acid Phosphatase/ACPP Protein-VLP, Human (386a.a, HEK293, His) is the recombinant human-derived Prostatic acid Phosphatase/ACPP protein-VLP, expressed by HEK293, with N-10*His labeled tag. The total length of Prostatic acid Phosphatase/ACPP Protein-VLP, Human (386a.a, HEK293, His) is 386 a.a., with molecular weight of 47.5 kDa.

HY-P70987

PPP1R1A Protein, Human (His)

Protein Phosphatase 1 Regulatory Subunit 1A; Protein Phosphatase Inhibitor 1; I-1; IPP-1; PPP1R1A; IPP1
Human E. coli

HY-P70361

	INPP1 Protein, Human (HEK293, His) rHuInositol polyphosphate 1-Phosphatase/INPP1, His; Inositol Polyphosphate 1-Phosphatase; IPP; IPPase; INPP1	Human	HEK293
	INPP1 protein, also known as inositol polyphosphate-1-phosphatase, is a phosphatase that plays a crucial role in inositol phosphate metabolism. The activity of this protein depends on magnesium ions and is responsible for catalyzing the hydrolysis of the phosphate group at position 1 of inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate. INPP1 Protein, Human (HEK293, His) is the recombinant human-derived INPP1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of INPP1 Protein, Human (HEK293, His) is 399 a.a., with molecular weight of 40-50 kDa.

HY-P7817A

	*Prostatic acid phosphatase/ACPP Protein, Human (HEK293, His)* Prostatic Acid Phosphatase; PAP; 5'-Nucleotidase; 5'-NT, Ecto-5'-Nucleotidase; Thiamine MonoPhosphatase; TMPase; ACPP	Human	HEK293
	Acid prostatic phosphatase (ACPP) is an enzyme that catalyzes the conversion of orthophosphate monoesters into alcohol and orthophosphate. ACPP is regulated by androgens and secreted by prostate epithelial cells. Prostatic acid phosphatase/ACPP Protein, Human (HEK293, His) is the recombinant human-derived Prostatic acid phosphatase/ACPP protein, expressed by HEK293 , with C-His labeled tag. The total length of Prostatic acid phosphatase/ACPP Protein, Human (HEK293, His) is 350 a.a., with molecular weight of 43-55 kDa.

HY-P71692

	ALPI Protein, Human (His) Alkaline Phosphatase intestinal; GlyceroPhosphatase; IAP	Human	E. coli
	ALPI Proteinas, an alkaline phosphatase, effectively hydrolyzes diverse phosphate compounds. ALPI Protein, Human (His) is the recombinant human-derived ALPI protein, expressed by E. coli , with N-His labeled tag. The total length of ALPI Protein, Human (His) is 475 a.a., with molecular weight of ~55.5 kDa.

HY-P75979

	PPM1A Protein, Mouse (His) Protein Phosphatase 1A; Protein Phosphatase 2C Isoform Alpha; PP2C-Alpha; PPPM1A	Mouse	E. coli
	PPM1A is a multifunctional enzyme whose enzymatic activity exhibits broad specificity. It acts as a negative regulator of TGF-β signaling by dephosphorylating SMAD2 and SMAD3, leading to their dissociation from SMAD4, nuclear export of SMAD, and termination of TGF-β-mediated signaling. PPM1A Protein, Mouse (His) is the recombinant mouse-derived PPM1A protein, expressed by E. coli , with C-His labeled tag. The total length of PPM1A Protein, Mouse (His) is 382 a.a., with molecular weight of ~44 kDa.

HY-P77821

	PLD4 Protein, Mouse (HEK293, His) 5'-3' exonuclease PLD4; Choline Phosphatase 4; Phospholipase D4; PLD 4	Mouse	HEK293
	PLD4 Protein, with 5'->3' DNA exonuclease activity, efficiently digests single-stranded DNA (ssDNA). It crucially regulates inflammatory cytokine responses by degrading nucleic acids, reducing ssDNA concentrations activating TLR9. Additionally, PLD4 actively participates in the phagocytosis process of activated microglia, emphasizing its role in immune responses. PLD4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PLD4 protein, expressed by HEK293, with C-His labeled tag. The total length of PLD4 Protein, Mouse (HEK293, His) is 446 a.a., with molecular weight of 60-80 kDa.

HY-P78019

	PLD4 Protein, Human (HEK293, His) 5'-3' exonuclease PLD4; Choline Phosphatase 4; Phospholipase D4; PLD 4	Human	HEK293
	PLD4 Protein, a phospholipase, plays a crucial role in immune responses and inflammation. Dysregulation of PLD4 Protein has been associated with autoimmune disorders and inflammatory diseases. Targeting PLD4 Protein may provide potential therapeutic interventions in these conditions by modulating immune responses, suppressing inflammation, and managing related disorders. PLD4 Protein, Human (HEK293, His) is the recombinant human-derived PLD4 protein, expressed by HEK293, with C-His labeled tag. The total length of PLD4 Protein, Human (HEK293, His) is 455 a.a., with molecular weight of 68-75 kDa.

HY-P75974

	PHOSPHO1 Protein, Human (His) Phosphoethanolamine/phosphocholine Phosphatase; PHOSPHO1	Human	E. coli
	PHOSPHO1 Protein, a phosphatase, is crucial in generating inorganic phosphate for bone mineralization, displaying high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho). It collaborates with PHOSPHO1 in skeletal mineralization, initiating hydroxyapatite crystallization in matrix vesicles (MVs), while ALPL/TNAP catalyzes hydroxyapatite crystallization in the extracellular matrix. PHOSPHO1 Protein, Human (His) is the recombinant human-derived PHOSPHO1 protein, expressed by E. coli , with N-His labeled tag. The total length of PHOSPHO1 Protein, Human (His) is 267 a.a., with molecular weight of ~32 kDa.

HY-P71620

	PNKP Protein, Human (His-SUMO) 2''(3'')-polynucleotidase; 2'(3')-polynucleotidase; Bifunctional polynucleotide Phosphatase/kinase; DEM 1; DEM1; Polynucleotide kinase-3''-Phosphatase	Human	E. coli
	PNKP protein plays a key role in DNA damage repair through NHEJ and BER pathways. Its dual catalytic activity includes removal of the 3'-phosphate group from the DNA backbone and phosphorylation of the 5'-hydroxyl group, ensuring compatibility of DNA ends during extension and ligation. PNKP Protein, Human (His-SUMO) is the recombinant human-derived PNKP protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of PNKP Protein, Human (His-SUMO) is 521 a.a., with molecular weight of ~70 kDa.

HY-P78019A

	PLD4 Protein, Human (HEK293, C-His) 5'-3' exonuclease PLD4; Choline Phosphatase 4; Phospholipase D4; PLD 4	Human	HEK293
	PLD4 Protein, a phospholipase, plays a crucial role in immune responses and inflammation. Dysregulation of PLD4 Protein has been associated with autoimmune disorders and inflammatory diseases. Targeting PLD4 Protein may provide potential therapeutic interventions in these conditions by modulating immune responses, suppressing inflammation, and managing related disorders. PLD4 Protein, Human (HEK293, C-His) is the recombinant human-derived PLD4 protein, expressed by HEK293, with C-10*His labeled tag. The total length of PLD4 Protein, Human (HEK293, C-His) is 455 a.a., with molecular weight (glycosylation form) of 75-85 kDa.

HY-P701992

λPP Protein, Escherichia phage lambda (His, FLAG)

Serine/threonine-protein Phosphatase
Others E. coli

HY-P71245

	PTP4A2 Protein, Human (His) Protein tyrosine Phosphatase type IVA 2; PTP4A2; HU-PP-1; OV-1; PTP(CAAXII); Protein-tyrosine Phosphatase 4a2; Protein-tyrosine Phosphatase of regenerating liver 2; PRL-2	Human	E. coli
	The PTP4A2 protein is an influential tyrosine phosphatase that stimulates G1 to S phase progression and contributes to cell cycle regulation. Notably, it promotes tumorigenesis, revealing its involvement in cancer development. PTP4A2 Protein, Human (His) is the recombinant human-derived PTP4A2 protein, expressed by E. coli , with C-6*His labeled tag. The total length of PTP4A2 Protein, Human (His) is 167 a.a., with molecular weight of ~20 kDa.

HY-P71228

	PPP1CC Protein, Human (His) Serine/Threonine-Protein Phosphatase PP1-Gamma Catalytic Subunit; PP-1G; Protein Phosphatase 1C Catalytic Subunit; PPP1CC	Human	E. coli
	PPP1CC protein is a multifunctional phosphatase that forms a specific holoenzyme with more than 200 regulatory proteins to dephosphorylate various biological targets. PPP1CC is critical for cell division and regulates glycogen metabolism, muscle contractility, and protein synthesis. PPP1CC Protein, Human (His) is the recombinant human-derived PPP1CC protein, expressed by E. coli , with N-6His, C-6His labeled tag. The total length of PPP1CC Protein, Human (His) is 323 a.a., with molecular weight of 30-40 kDa.

HY-P7884

	CD45 Protein, Mouse (HEK293, His) rMuReceptor-type tyrosine-protein Phosphatase C/CD45, His; B220; CD45 antigen; CD45; CD45R; LCA; L-CA; LY5; protein tyrosine Phosphatase, receptor type, C; PTPRC; receptor-type tyrosine-protein Phosphatase C	Mouse	HEK293
	CD45/PTPRC Protein, Mouse (HEK 293, His) expresses in HEK293 with a His tag at the N-terminus. CD45 is a transmembrane glycoprotein, expressed on almost all haematopoietic cells except for mature erythrocytes. PTPRC is an essential regulator of T and B cell antigen receptor-mediated activation.

HY-P7887

	CD45 Protein, Human (552a.a, HEK293, His) rHuReceptor-type tyrosine-protein Phosphatase C/CD45, His; B220; CD45 antigen; CD45; CD45R; LCA; L-CA; LY5; protein tyrosine Phosphatase, receptor type, C; PTPRC; receptor-type tyrosine-protein Phosphatase C	Human	HEK293
	CD45 Protein, Human (HEK 293, His) is a type 1 transmembrane protein tyrosine phosphatase (PTPase) expressed by all the haematopoietic stem cells (HSCs) except that of erythrocytes and platelets.

Cat. No.	Product Name	Application	Reactivity

HY-P80645

DUSP1 Antibody DUSP1; CL100; MKP1; PTPN10; VH1; Dual specificity protein Phosphatase 1; Dual specificity protein Phosphatase hVH1; Mitogen-activated protein kinase Phosphatase 1; MAP kinase Phosphatase 1; MKP-1; Protein-tyrosine Phosphatase CL100	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
DUSP1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 39 kDa, targeting to DUSP1. It can be used for WB,IHC-P,ICC/IF,IP,FC assays with tag free, in the background of Human, Mouse, Rat.

HY-P81304

Placental Alkaline Phosphatase Antibody (YA1038)

ALPP; PLAP; Alkaline Phosphatase; placental type; Alkaline Phosphatase Regan isozyme; Placental alkaline Phosphatase 1; PLAP-1
WB Human
HY-P81304A

Placental Alkaline Phosphatase Antibody (YA1039)

ALPP; PLAP; Alkaline Phosphatase; placental type; Alkaline Phosphatase Regan isozyme; Placental alkaline Phosphatase 1; PLAP-1
WB Human

HY-P80012

*Alkaline Phosphatase* Antibody**	WB, ICC, IHC-P, IP, FC	Human, Mouse
Alkaline Phosphatase Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 57 kDa, targeting to Alkaline Phosphatase. It can be used for WB,ICC,IHC-P,IP,FC assays with tag free, in the background of Human, Mouse.

HY-P81324

PPP5C Antibody (YA1069) FLJ36922; FLJ55954; OTTHUMP00000165834; PP-T; PP5; PPP5; PPP5_HUMAN; PPP5C; PPT; Protein Phosphatase 5; catalytic subunit; Protein Phosphatase T; Serine/threonine protein Phosphatase 5; Serine/threonine-protein Phosphatase 5.	WB	Human

HY-P83087

SHIP1 Antibody (YA2832) INPP5D; SHIP; SHIP1; Phosphatidylinositol 3; 4; 5-trisphosphate 5-Phosphatase 1; Inositol polyphosphate-5-Phosphatase of 145 kDa; SIP-145; SH2 domain-containing inositol 5'-Phosphatase 1; SH2 domain-containing inositol Phosphatase 1; SHIP-1	WB, IHC-P, IP, FC	Human

HY-P82879

CDC25C Antibody (YA2624)

CDC25C; M-phase inducer Phosphatase 3; Dual specificity Phosphatase Cdc25C
WB, IHC-P, ICC/IF, IP, FC Human

HY-P80646

DUSP3 Antibody Dual specificity protein Phosphatase VHR; VHR; Vaccinia H1-related Phosphatase	WB, IHC-F, IHC-P, ICC/IF, FC, IP	Human, Mouse, Rat
DUSP3 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 20 kDa, targeting to DUSP3. It can be used for WB,IHC-F,IHC-P,ICC/IF,FC,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P83344

Phospho-SHIP1 (Tyr1020) Antibody (YA3089) INPP5D; SHIP; SHIP1; Phosphatidylinositol 3; 4; 5-trisphosphate 5-Phosphatase 1; Inositol polyphosphate-5-Phosphatase of 145 kDa; SIP-145; SH2 domain-containing inositol 5'-Phosphatase 1; SH2 domain-containing inositol Phosphatase 1; SHIP-1	WB, ICC/IF, IP	Human

HY-P81961

Prostatic Acid Phosphatase Antibody (YA1706)

5' -NT; 5' -nucleotidase; ACP3; PAP; Prostatic acid Phosphatase; TMPase
WB, IHC-P, ICC/IF, IP Human

HY-P81323

PP1C gamma Antibody (YA1068) PP 1G; PP-1G; PP1G; PP1G_HUMAN; PP1gamma; PPP 1G; PPP1CC; PPP1CC protein; PPP1G; Protein Phosphatase 1 catalytic subunit gamma isoform; Protein Phosphatase 1C catalytic subunit; Protein Phosphatase 1C subunit; Protein Phosphatase 2C gamma isoform; Serine/threonine Phosphatase 1 gamma; Serine/threonine protein Phosphatase PP1 gamma catalytic subunit; Serine/threonine-protein Phosphatase PP1-gamma catalytic subunit.	WB	Human

HY-P81307

SHP1 Antibody (YA1044) PTPN6; HCP; PTP1C; Tyrosine-protein Phosphatase non-receptor type 6; Hematopoietic cell protein-tyrosine Phosphatase; Protein-tyrosine Phosphatase 1C; PTP-1C; Protein-tyrosine Phosphatase SHP-1; SH-PTP1	WB, IP	Human

HY-P81307A

SHP1 Antibody (YA1045) PTPN6; HCP; PTP1C; Tyrosine-protein Phosphatase non-receptor type 6; Hematopoietic cell protein-tyrosine Phosphatase; Protein-tyrosine Phosphatase 1C; PTP-1C; Protein-tyrosine Phosphatase SHP-1; SH-PTP1	WB, IHC-P	Human

HY-P81305

PP1C alpha Antibody (YA1040) Alpha isoform serine threonine protein Phosphatase PP1alpha 1 catalytic subunit; Catalytic subunit; PP1A; PP1A_HUMAN; PP1alpha; PP2C ALPHA; PP2CA; Ppp1ca; Protein Phosphatase 2C Alpha Isoform; Serine threonine protein Phosphatase PP1 alpha catalytic subunit; Serine threonine protein Phosphatase PP1 alpha catalytic subunit protein Phosphatase 1; Serine/threonine-protein Phosphatase PP1-alpha catalytic subunit.	WB, IHC-F, IHC-P, ICC/IF	Human

HY-P81305A

PP1C alpha Antibody (YA1041) Alpha isoform serine threonine protein Phosphatase PP1alpha 1 catalytic subunit; Catalytic subunit; PP1A; PP1A_HUMAN; PP1alpha; PP2C ALPHA; PP2CA; Ppp1ca; Protein Phosphatase 2C Alpha Isoform; Serine threonine protein Phosphatase PP1 alpha catalytic subunit; Serine threonine protein Phosphatase PP1 alpha catalytic subunit protein Phosphatase 1; Serine/threonine-protein Phosphatase PP1-alpha catalytic subunit.	WB, ICC/IF	Human

HY-P81348

PHLPP2 Antibody (YA1093) PHLPP2; KIAA0931, PHLPPL; PH domain leucine-rich repeat-containing protein Phosphatase 2; PH domain leucine-rich repeat-containing protein Phosphatase-like (PHLPP-like)	IHC-P	Human

HY-P81491

INPP4B Antibody (YA1236) 4-bisphosphate 4-Phosphatase; Inositol polyphosphate 4 Phosphatase type II 105kDa; Inositol polyphosphate 4-Phosphatase type II; Inpp4b; MGC132014; Type II inositol 3; 4 bisphosphate 4 Phosphatase; Type II inositol-3	IHC-P	Human

HY-P81955

PP1C alpha/beta Antibody (YA1700) Alpha isoform serine threonine protein Phosphatase PP1alpha 1 catalytic subunit; Catalytic subunit; PP1A; PP1A_HUMAN; PP1alpha; PP2C ALPHA; PP2CA; Ppp1ca; Protein Phosphatase 2C Alpha Isoform; Serine threonine protein Phosphatase PP1 alpha catalytic subunit; Serine threonine protein Phosphatase PP1 alpha catalytic subunit protein Phosphatase 1; Serine/threonine-protein Phosphatase PP1-alpha catalytic subunit.	WB, IHC-P, IP	Human, Mouse, Rat

HY-P82535

DUSP6 Antibody (YA2280)

HH19; MKP3; PYST1; DUSP6; DUSP6a; Dual specificity Phosphatase 6
WB, IHC-P, ICC/IF, IP, FC Human, Mouse, Rat
HY-P81814

Intestinal Alkaline Phosphatase Antibody (YA1559)

Alpi; GlyceroPhosphatase; IAP
WB, IHC-P Human
HY-P81953

PPM1G Antibody (YA1698)

Protein Phosphatase 1G; PP2C-gamma; Protein Phosphatase magnesium-dependent 1 gamma
WB Human, Mouse, Rat
HY-P82031

PTP1B Antibody (YA1776)

PTPN1; PTP1B; Tyrosine-protein Phosphatase non-receptor type 1; Protein-tyrosine Phosphatase 1B; PTP-1B
WB, IHC-F, IHC-P, ICC/IF Human
HY-P82899

DARPP32 Antibody (YA2644)

PPP1R1B; DARPP32; Protein Phosphatase 1 regulatory subunit 1B; DARPP-32; Dopamine- and cAMP-regulated neuronal phosphoprotein
WB, IHC-P, IP Human, Mouse, Rat

HY-P81898

SHP2 Antibody (YA1643) PTPN11; PTP2C; SHPTP2; Tyrosine-protein Phosphatase non-receptor type 11; Protein-tyrosine Phosphatase 1D; PTP-1D; Protein-tyrosine Phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3	WB, IHC-P, IP	Human

HY-P81300

Phospho-PTP1B (Ser352) Antibody (YA1027)

PTPN1; PTP1B; Tyrosine-protein Phosphatase non-receptor type 1; Protein-tyrosine Phosphatase 1B; PTP-1B
WB, ICC/IF, IP Human
HY-P81300A

Phospho-PTP1B (Ser378) Antibody (YA1028)

PTPN1; PTP1B; Tyrosine-protein Phosphatase non-receptor type 1; Protein-tyrosine Phosphatase 1B; PTP-1B
WB, IHC-P Human
HY-P83364

PPP1R1A Antibody (YA3109)

I 1; I1; Inhibitor 1; IPP1; Ppp1r1a; Protein Phosphatase 1 regulatory (inhibitor) subunit 1A
WB, IHC-P, ICC/IF, IP, FC Human, Mouse, Rat

HY-P80816

Phospho-FAK (Tyr576) Antibody PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein Phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK	WB	Human, Mouse
Phospho-FAK (Tyr576) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 119 kDa, targeting to Phospho-FAK (Tyr576). It can be used for WB assays with tag free, in the background of Human, Mouse.

HY-P80603

CD45 Antibody (YA800) PTPRC; CD45; Receptor-type tyrosine-protein Phosphatase C; Leukocyte common antigen; L-CA; T200; CD antigen CD45	WB, IHC-P	Human, Mouse
CD45 Antibody (YA800) is a non-conjugated and Mouse origined monoclonal antibody about 147 kDa, targeting to CD45. It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse.

HY-P81958

PP1C beta Antibody (YA1703)

PPP1CB; Serine/threonine-protein Phosphatase PP1-beta catalytic subunit; PP-1B; PPP1CD
WB, IHC-F, IHC-P, ICC/IF, IP Human, Mouse, Rat

HY-P81948

PP2A alpha/beta Antibody (YA1693) PPP2CA; Serine/threonine-protein Phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; Replication protein C; RP-C	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat, Hamster

HY-P82763

Calcineurin A Antibody (YA2508) PPP3CA; CALNA; CNA; Serine/threonine-protein Phosphatase 2B catalytic subunit alpha isoform; CAM-PRP catalytic subunit; Calmodulin-dependent calcineurin A subunit alpha isoform	WB, ICC/IF, FC	Human, Mouse, Rat

HY-P83111

Phospho-PP2A alpha (Tyr307) Antibody (YA2856) PPP2CA; Serine/threonine-protein Phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; Replication protein C; RP-C	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat

HY-P83448

PTP4A2 Antibody (YA3193)

protein tyrosine Phosphatase type IVA; member 2; HH13; OV-1; PRL2; HH7-2; PRL-2; PTP4A; HU-PP-1; PTPCAAX2; ptp-IV1a; ptp-IV1b
WB, IP Human

HY-P81616

SIRP alpha Antibody (YA1361) SIRPA; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP; Tyrosine-protein Phosphatase non-receptor type substrate 1; SHP substrate 1; SHPS-1; Brain Ig-like molecule with tyrosine-based activation motifs; Bit; CD172 antigen-like family member A; Inhibito	FC, ELISA	Human

HY-P80785

PGP9.5 Antibody UCHL1 / PGP9.5; UCHL1; B220; CD 45; CD45; cd45 antigen; ec3.1.3.48; GP 180; GP180; Human homolog of severe combined immunodeficiency due to PTPRC deficiency; L CA; L-CA; lca; Leukocyte common antigen; LY 5; LY5; Protein tyrosine Phosphatase receptor type	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
PGP9.5 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 25 kDa, targeting to PGP9.5. It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.

Cat. No.	Product Name		Classification

HY-130913

5-FAM-Alkyne		Alkynes
5-FAM-Alkyne is a high selective and sensitive fluorescent biosensor for alkaline phosphatase (ALP) . 5-FAM-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-135699

TD52 1 Publications Verification		Alkynes
TD52, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of *protein phosphatase* 2A (CIP2A) inhibitor. TD52 mediates the apoptotic** effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 has less p-EGFR inhibition and has potent anti-cancer activity . TD52 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-135699A

TD52 dihydrochloride 1 Publications Verification		Alkynes
TD52 dihydrochloride, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of *protein phosphatase* 2A (CIP2A) inhibitor. TD52 dihydrochloride mediates the apoptotic** effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 dihydrochloride indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 dihydrochloride has less p-EGFR inhibition and has potent anti-cancer activity . TD52 (dihydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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