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Results for "

Pioglitazone

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

5

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13956
    Pioglitazone
    Maximum Cited Publications
    25 Publications Verification

    U 72107

    		 PPAR Ferroptosis Metabolic Disease Cancer
    Pioglitazone (U 72107) is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively. Pioglitazone can be used in diabetes research .
    <em>Pioglitazone</em>
  • HY-13956S
    Pioglitazone-d4

    U 72107-d4

    		 PPAR Ferroptosis Metabolic Disease Cancer
    Pioglitazone-d4 is a deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively[1].
    <em>Pioglitazone</em>-d4
  • HY-13956S1
    Pioglitazone-d4 (alkyl)

    		Isotope-Labeled Compounds PPAR Ferroptosis Metabolic Disease Cancer
    Pioglitazone-d4 (alkyl) (U 72107-d4 (alkyl)) is the deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively[1][2].
    <em>Pioglitazone</em>-d4 (alkyl)
  • HY-14601R
    Pioglitazone hydrochloride (Standard)

    U 72107A (Standard); AD 4833 (Standard)

    		 PPAR Ferroptosis Metabolic Disease Cancer
    Pioglitazone (hydrochloride) (Standard) is the analytical standard of Pioglitazone (hydrochloride). This product is intended for research and analytical applications. Pioglitazone hydrochloride is a potent and selective PPARγ agonist with EC50s of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.
    <em>Pioglitazone</em> hydrochloride (Standard)
  • HY-13956B
    Pioglitazone potassium

    U 72107 potassium

    		 PPAR Ferroptosis Metabolic Disease Cancer
    Pioglitazone (U 72107) potassium is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 μM and 0.99 μM for human and mouse PPARγ, respectively. Pioglitazone potassium can be used in diabetes research .
    <em>Pioglitazone</em> potassium
  • HY-14601
    Pioglitazone hydrochloride
    Maximum Cited Publications
    25 Publications Verification

    U 72107A; AD 4833

    		 PPAR Ferroptosis Metabolic Disease Cancer
    Pioglitazone hydrochloride is a potent and selective PPARγ agonist with EC50s of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.
    <em>Pioglitazone</em> hydrochloride
  • HY-144145S
    Hydroxy Pioglitazone (M-II)-d4

    		Isotope-Labeled Compounds Others
    Hydroxy Pioglitazone (M-II)-d4 is the deuterium labeled Hydroxy Pioglitazone (M-II)[1].
    Hydroxy <em>Pioglitazone</em> (M-II)-d4
  • HY-132379S
    Hydroxy Pioglitazone-d5 (M-IV) (Mixture of-diastereomers)

    		Isotope-Labeled Compounds Others
    Hydroxy Pioglitazone-d5 (M-IV) (Mixture of-diastereomers) is the deuterium labeled Hydroxy Pioglitazone (M-IV) (Mixture of-diastereomers)[1].
    Hydroxy <em>Pioglitazone</em>-d5 (M-IV) (Mixture of-diastereomers)
  • HY-117727
    Leriglitazone

    MIN-102; HydroxyPioglitazone

    		 PPAR Metabolic Disease
    Leriglitazone (MIN-102; Hydroxypioglitazone), a metabolite of pioglitazone. Leriglitazone PioOH is a PPARγ agonist, stabilizes the PPARγ activation function-2 (AF-2) co-activator binding surface and enhances co-activator binding, affording slightly better transcriptional efficacy. Leriglitazone binds to the PPARγ C-terminal ligand-binding domain (LBD) with a Ki of 1.2 μM，Leriglitazone induces transcriptional efficacy of the PPARγ (LBD) with an EC50 of 680 nM .
    Leriglitazone
  • HY-117727A
    Leriglitazone hydrochloride

    MIN-102 hydrochloride; HydroxyPioglitazone hydrochloride

    		 PPAR Metabolic Disease
    Leriglitazone (MIN-102; Hydroxypioglitazone) hydrochloride, a metabolite of pioglitazone. Leriglitazone hydrochloride PioOH is a PPARγ agonist, stabilizes the PPARγ activation function-2 (AF-2) co-activator binding surface and enhances co-activator binding, affording slightly better transcriptional efficacy. Leriglitazone hydrochloride binds to the PPARγ C-terminal ligand-binding domain (LBD) with a Ki of 1.2 μM，Leriglitazone induces transcriptional efficacy of the PPARγ (LBD) with an EC50 of 680 nM .
    Leriglitazone hydrochloride
  • HY-117727S
    Leriglitazone-d4

    MIN-102-d4; HydroxyPioglitazone-d4

    		 Isotope-Labeled Compounds PPAR Metabolic Disease
    Leriglitazone-d4 (MIN-102-d4; Hydroxypioglitazone-d4) is deuterium labeled Leriglitazone. Leriglitazone (Hydroxypioglitazone), a metabolite of pioglitazone.Leriglitazone (Hydroxypioglitazone) PioOH is a PPARγ agonist, stabilizes the PPARγ activation function-2 (AF-2) co-activator binding surface and enhances co-activator binding, affording slightly better transcriptional efficacy.Leriglitazone (Hydroxypioglitazone) binds to the PPARγ C-terminal ligand-binding domain (LBD) with Ki of 1.2 μM，induces transcriptional efficacy of the PPARγ (LBD) with EC50 of 680 nM .
    Leriglitazone-d4

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