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Results for "

Podophyllotoxin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Autophagy (1) Microtubule/Tubulin (4) Topoisomerase (1)
By Research Areas:	Cancer (6) Cardiovascular Disease (1) Infection (1)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15552

Podofilox

3 Publications Verification

Podophyllotoxin
Microtubule/Tubulin Cancer

Podofilox (Podophyllotoxin) is a potent inhibitor of microtubule assembly and DNA topoisomerase II.
HY-N1977

Podophyllotoxin glucoside

Podophyllotoxin glucoside is a podophyllotoxin derivative, has anti-tumor effects .
HY-13761

Teniposide

5+ Cited Publications

VM26
Topoisomerase Cancer

Teniposide is a podophyllotoxin derivative, acts as a topoisomerase II inhibitor, and used as a chemotherapeutic agent.
HY-N7685

Podophyllol

Others Cancer

Podophyllol, a derivative of podophyllotoxin esters, has antitumor activity .
HY-N12034

Picropodophyllin-β-D-glucoside

Others Others

Picropodophyllin-β-D-glucoside (compound 3) is a podophyllotoxin glucoside isolated from Chinese medicinal plants .

Podofilox 3 Publications Verification Podophyllotoxin	Microtubule/Tubulin	Cancer
Podofilox (Podophyllotoxin) is a potent inhibitor of microtubule assembly and DNA topoisomerase II.

Podophyllotoxin glucoside
Podophyllotoxin glucoside is a podophyllotoxin derivative, has anti-tumor effects .

Teniposide 5+ Cited Publications VM26	Topoisomerase	Cancer
Teniposide is a podophyllotoxin derivative, acts as a topoisomerase II inhibitor, and used as a chemotherapeutic agent.

Podophyllol	Others	Cancer
Podophyllol, a derivative of podophyllotoxin esters, has antitumor activity .

Picropodophyllin-β-D-glucoside	Others	Others
Picropodophyllin-β-D-glucoside (compound 3) is a podophyllotoxin glucoside isolated from Chinese medicinal plants .

HY-N9926

Pluviatolide (-)-Pluviatolide	Others	Others
Pluviatolide ((-)-Pluviatolide) is a lignan that can be found in the bark of Zanthoxylum pluviatile Hartley. Pluviatolide can be used as (-)-Podophyllotoxin precursor .

HY-15552S

Podofilox-d6	Microtubule/Tubulin	Cancer
Podofilox-d₆ is the deuterium labeled Podofilox. Podofilox (Podophyllotoxin) is a potent inhibitor of microtubule assembly and DNA topoisomerase II[1][2].

HY-N8745

α-Peltatin

Others Others

α-Peltatin is an aryl lignan. α-Peltatin has anticancer and antifungal activity. α-Peltatin inhibits DNA topoisomerase and tubulin polymerization .

α-Peltatin	Others	Others
α-Peltatin is an aryl lignan. α-Peltatin has anticancer and antifungal activity. α-Peltatin inhibits DNA topoisomerase and tubulin polymerization .

HY-N2500

Deoxypodophyllotoxin	Microtubule/Tubulin Apoptosis Autophagy	Infection Cardiovascular Disease
Deoxypodophyllotoxin (DPT), a derivative of podophyllotoxin, is a lignan with potent antimitotic, anti-inflammatory and antiviral properties isolated from Anthriscus sylvestris. Deoxypodophyllotoxin, targets the microtubule, has a major impact in oncology not only as anti-mitotics but also as potent inhibitors of angiogenesis . Deoxypodophyllotoxin induces cell autophagy and apoptosis . Deoxypodophyllotoxin evokes increase of intracellular Ca ²⁺ concentrations in DRG neurons .

HY-146114

Antitumor agent-67	Others	Cancer
Antitumor agent-67 (compound 3) is a potent antitumor agent. Antitumor agent-67 has highly selective toxicity to cancer cells and lower damage to normal cells. Antitumor agent-67 can be activated by NQO1 and effectively liberate podophyllotoxin and kill tumor cells. Antitumor agent-67 significantly suppresses cancer growth in HepG2 xenograft models without obvious toxicity .

HY-156088

SSE1806	Microtubule/Tubulin Apoptosis	Cancer
SSE1806 is a derivative of podophyllotoxin (a natural antimitotic agent) and a microtubule/tubulin inhibitor with significant anticancer and antiproliferative activities. The GI50 of SSE1806 on cancer cell growth ranges from 1.29-21.15 μM. SSE1806 causes mitotic abnormalities and G2/M phase arrest, increases p53 expression, and inhibits colon cancer organoid growth. SSE1806 is able to overcome multidrug resistance in cell lines overexpressing MDR-1 .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-15552

Podofilox 3 Publications Verification Podophyllotoxin	Classification of Application Fields Source classification Lignans Dysosma versipellis (Hance) M. Cheng ex Ying Phenylpropanoids Plants Berberidaceae Disease Research Fields Cancer	Microtubule/Tubulin
Podofilox (Podophyllotoxin) is a potent inhibitor of microtubule assembly and DNA topoisomerase II.

HY-N2500

Deoxypodophyllotoxin	Infection Cardiovascular Disease Structural Classification other families Classification of Application Fields Source classification Centaurea ornata Lignans Phenylpropanoids Plants Umbelliferae Disease Research Fields	Microtubule/Tubulin Apoptosis Autophagy
Deoxypodophyllotoxin (DPT), a derivative of podophyllotoxin, is a lignan with potent antimitotic, anti-inflammatory and antiviral properties isolated from Anthriscus sylvestris. Deoxypodophyllotoxin, targets the microtubule, has a major impact in oncology not only as anti-mitotics but also as potent inhibitors of angiogenesis . Deoxypodophyllotoxin induces cell autophagy and apoptosis . Deoxypodophyllotoxin evokes increase of intracellular Ca ²⁺ concentrations in DRG neurons .

HY-N12034

Picropodophyllin-β-D-glucoside	Structural Classification Sinopodophyllum hexandrum (Royle) Ying Source classification Lignans Phenylpropanoids Plants Berberidaceae Saccharides Monosaccharides	Others
Picropodophyllin-β-D-glucoside (compound 3) is a podophyllotoxin glucoside isolated from Chinese medicinal plants .

HY-N9926

Pluviatolide (-)-Pluviatolide	Zanthoxylum bungeanum Maxim. Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Rutaceae Phenols Plants Disease Research Fields	Others
Pluviatolide ((-)-Pluviatolide) is a lignan that can be found in the bark of Zanthoxylum pluviatile Hartley. Pluviatolide can be used as (-)-Podophyllotoxin precursor .

HY-N8745

α-Peltatin	Structural Classification Source classification Podophyllum peltatum L. Lignans Phenylpropanoids Plants Berberidaceae	Others
α-Peltatin is an aryl lignan. α-Peltatin has anticancer and antifungal activity. α-Peltatin inhibits DNA topoisomerase and tubulin polymerization .

Cat. No.	Product Name	Chemical Structure

HY-15552S

Podofilox-d6

Podofilox-d₆ is the deuterium labeled Podofilox. Podofilox (Podophyllotoxin) is a potent inhibitor of microtubule assembly and DNA topoisomerase II[1][2].

Podofilox-d6
Podofilox-d₆ is the deuterium labeled Podofilox. Podofilox (Podophyllotoxin) is a potent inhibitor of microtubule assembly and DNA topoisomerase II[1][2].

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Podophyllotoxin

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
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