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Pomalidomide-PEG1-azide

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-133138
    Pomalidomide-PEG1-azide

    		E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Pomalidomide-PEG1-azide incorporates the Pomalidomide based cereblon ligand and a linker.?Pomalidomide-PEG1-azide?can be used to design a?PROTAC BRD4 Degrader-1 (HY-133131) [1]. Pomalidomide-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    <em>Pomalidomide-PEG1</em>-<em>azide</em>

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