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Results for "

RCC

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (2) Apoptosis (2) Autophagy (2) Bacterial (2) GLUT (1) HIF/HIF Prolyl-Hydroxylase (1) Histone Demethylase (1) Isotope-Labeled Compounds (1) MDM-2/p53 (1) Phosphodiesterase (PDE) (1) Small Interfering RNA (siRNA) (2) TAM Receptor (1) TNF Receptor (1) Topoisomerase (1) VEGFR (2)
By Research Areas:	Cancer (10) Infection (2) Inflammation/Immunology (2)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-I0636

(R)-Apremilast

(R)-CC-10004
Others Inflammation/Immunology

(R)-Apremilast ((R)-CC-10004) is a enantiomer of Apremilast .

(R)-Apremilast (R)-CC-10004	Others	Inflammation/Immunology
(R)-Apremilast ((R)-CC-10004) is a enantiomer of Apremilast .

HY-100746

STF-62247 1 Publications Verification	Autophagy	Cancer
STF-62247 is an autophagy inducer that selectively cytotoxic to VHL-deficient renal cell carcinoma (IC₅₀ of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively) .

HY-119425

Razoxane

ICRF 159
Topoisomerase Cancer

Razoxane (ICRF 159) is an antiangiogenic topoisomerase II inhibitor, can be used for the research of renal cell carcinoma (RCC) .

Razoxane ICRF 159	Topoisomerase	Cancer
Razoxane (ICRF 159) is an antiangiogenic topoisomerase II inhibitor, can be used for the research of renal cell carcinoma (RCC) .

HY-RS11783

RCC1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
RCC1 Human Pre-designed siRNA Set A contains three designed siRNAs for RCC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

RCC1 Human Pre-designed siRNA Set A RCC1 Human Pre-designed siRNA Set A

HY-RS11784

RCC2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
RCC2 Human Pre-designed siRNA Set A contains three designed siRNAs for RCC2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

RCC2 Human Pre-designed siRNA Set A RCC2 Human Pre-designed siRNA Set A

HY-139782

SKLB325	Histone Demethylase Apoptosis	Cancer
SKLB325 is a Jumonji domain-containing 6 (JMJD6) inhibitor with a binding affinity (K_D) value of 0.755 μM, and the IC₅₀ value of 0.7797 μM. SKLB325 exhibits antitumor effects on ovarian cancer in vivo and in vitro. SKLB325 induces apoptosis . SKLB325 exhibits remarkable antitumor efficacy in renal cell carcinoma (RCC) .

HY-P99161

Tilvestamab BGB149	TAM Receptor	Cancer
Tilvestamab (BGB149) is a humanized anti-AXL antibody that blocks AXL-mediated cell signaling. Tilvestamab significantly inhibits Gas6-induced AXL activation in 786-0-Luc RCC cells and inhibits downstream AKT phosphorylation. Tilvestamab can be used in cancer research, particularly in AXL overexpressing renal cell carcinomas .

HY-12085S2

(Rac)-Apremilast-d5 (Rac)-CC-10004 d₅	Apoptosis Phosphodiesterase (PDE) TNF Receptor Isotope-Labeled Compounds	Inflammation/Immunology
(Rac)-Apremilast-d₅ is a deuterium labeled (R)-Apremilast. (R)-Apremilast ((R)-CC-10004) is a enantiomer of Apremilast[1].

HY-18728

STF-31 Maximum Cited Publications 9 Publications Verification	GLUT Autophagy	Cancer
STF-31 is a selective inhibitor of glucose transporter 1 (GLUT1), with an IC₅₀ of 1 μM. STF-31 is also a NAMPT inhibitor. STF-31 inhibits glucose uptake in renal cell carcinoma (RCC) 4 cells .

HY-122615

SPOP-IN-6b

1 Publications Verification

Others Cancer

SPOP-IN-6b is a speckle-type POZ protein (SPOP) inhibitor with an IC₅₀ of 3.58 μM (patent CN 107141287, SPOP-B-88) .

SPOP-IN-6b 1 Publications Verification	Others	Cancer
SPOP-IN-6b is a speckle-type POZ protein (SPOP) inhibitor with an IC₅₀ of 3.58 μM (patent CN 107141287, SPOP-B-88) .

HY-10977A

Tivozanib hydrochloride hydrate 5+ Cited Publications AV-951 hydrochloride hydrate; KRN951 hydrochloride hydrate	VEGFR	Cancer
Tivozanib hydrochloride hydrate is a selective and orally active VEGFR tyrosine kinase inhibitor with IC₅₀ of 0.21, 0.16, 0.24 nM for VEGFR-1, VEGFR-2, VEGFR-3, respectively. Tivozanib hydrochloride hydrate inhibits angiogenesis and vascular permeability in tumor tissues and shows antitumor activity. Tivozanib hydrochloride hydrate has the potential for the research of metastatic renal cell carcinoma (RCC) .

HY-10977

Tivozanib 5+ Cited Publications AV-951; KRN951	VEGFR	Cancer
Tivozanib (AV-951; KRN951) is a selective and orally active VEGFR tyrosine kinase inhibitor with IC₅₀ of 0.21, 0.16, 0.24 nM for VEGFR-1, VEGFR-2, VEGFR-3, respectively. Tivozanib inhibits angiogenesis and vascular permeability in tumor tissues and shows antitumor activity. Tivozanib has the potential for the research of metastatic renal cell carcinoma (RCC) .

HY-P2324

Gramicidin A 1 Publications Verification	Bacterial HIF/HIF Prolyl-Hydroxylase Antibiotic	Infection Cancer
Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A induces degradation of hypoxia inducible factor 1 α (HIF-1α) .

HY-P2324A

Gramicidin A TFA	Antibiotic Bacterial	Infection
Gramicidin A (TFA) is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A (TFA) is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A (TFA) induces degradation of hypoxia inducible factor 1 α (HIF-1α) .

HY-112780

UC2288 2 Publications Verification	MDM-2/p53	Cancer
UC2288 is a novel, cell-permeable, and orally active p21 attenuator (relatively selective activity for p21), which is synthesized based Sorafenib (HY-10201). UC2288 decreases p21 mRNA expression independently of p53, and attenuates p21 protein levels with minimal effect on p21 protein stability. UC2288 has no inhibition of VEGFR2 and Raf kinases even at 10 μM .

Cat. No.	Product Name	Target	Research Area

HY-P2324

Gramicidin A 1 Publications Verification	Bacterial HIF/HIF Prolyl-Hydroxylase Antibiotic	Infection Cancer
Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A induces degradation of hypoxia inducible factor 1 α (HIF-1α) .

HY-P2324A

Gramicidin A TFA	Antibiotic Bacterial	Infection
Gramicidin A (TFA) is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A (TFA) is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A (TFA) induces degradation of hypoxia inducible factor 1 α (HIF-1α) .

Cat. No.	Product Name	Target	Research Area

HY-P99161

Tilvestamab BGB149	TAM Receptor	Cancer
Tilvestamab (BGB149) is a humanized anti-AXL antibody that blocks AXL-mediated cell signaling. Tilvestamab significantly inhibits Gas6-induced AXL activation in 786-0-Luc RCC cells and inhibits downstream AKT phosphorylation. Tilvestamab can be used in cancer research, particularly in AXL overexpressing renal cell carcinomas .

Species:	Human (6) Mouse (1) Cynomolgus (1) Canine (2)
Tag:	His (8) Avi (2) Fc (2)
Source:	HEK293 (8) P. pastoris (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P700882

	Carbonic Anhydrase 9 Protein, Cynomolgus (HEK293, His) CA9; CAIX; CA-IX; EC 4.2.1.1; G250; MN; P54/58N; PMW1; RCC	Cynomolgus	HEK293
	Carbonic Anhydrase 9 Protein catalyzes the reversible hydration of carbon dioxide, essential for converting it to bicarbonate ions and protons, and vice versa. This enzymatic activity is crucial in physiological processes like acid-base balance regulation, respiration, and cellular pH homeostasis. Carbonic Anhydrase 9 Protein is vital for carbon dioxide transport and metabolism, contributing to overall regulation of its levels in the body. Carbonic Anhydrase 9 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-His labeled tag. The total length of Carbonic Anhydrase 9 Protein, Cynomolgus (HEK293, His) is 365 a.a., with molecular weight of 50-60 kDa.

HY-P70064

	Carbonic Anhydrase 9 Protein, Human (HEK293, His) rHuCarbonic Anhydrase 9/CA9, His; CA9; CA-IX; Carbonic Anhydrase IX; Carbonate dehydratase IX; G250; MN; P54/58N; RCC; RCC-associated protein G250	Human	HEK293
	The carbonic anhydrase 9 (CA9) protein plays a crucial role as a catalyst in the conversion of carbon dioxide and water. It promotes the formation of bicarbonate and hydrogen ions (dissociated ions of carbonic acid). Carbonic Anhydrase 9 Protein, Human (HEK293, His) is the recombinant human-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Carbonic Anhydrase 9 Protein, Human (HEK293, His) is 377 a.a., with molecular weight of 45-60 kDa.

HY-P72348

	Carbonic Anhydrase 9 Protein, Human (Biotinylated, HEK293, Avi-His) CA9; CA-IX; Carbonic Anhydrase IX; Carbonate dehydratase IX; G250; MN; P54/58N; RCC; RCC-associated protein G250	Human	HEK293
	The carbonic anhydrase 9 (CA9) protein plays a crucial role as a catalyst in the conversion of carbon dioxide and water. It promotes the formation of bicarbonate and hydrogen ions (dissociated ions of carbonic acid). Carbonic Anhydrase 9 Protein, Human (Biotinylated, HEK293, Avi-His) is the recombinant human-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of Carbonic Anhydrase 9 Protein, Human (Biotinylated, HEK293, Avi-His) is 377 a.a., with molecular weight of ~60 kDa.

HY-P78396

	Carbonic Anhydrase 9 Protein, Human (HEK293, His-Avi) CA9; CAIX; CA-IX; EC 4.2.1.1; G250; MN; P54/58N; PMW1; RCC	Human	HEK293
	The carbonic anhydrase 9 (CA9) protein plays a crucial role as a catalyst in the conversion of carbon dioxide and water. It promotes the formation of bicarbonate and hydrogen ions (dissociated ions of carbonic acid). Carbonic Anhydrase 9 Protein, Human (HEK293, His-Avi) is the recombinant human-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Carbonic Anhydrase 9 Protein, Human (HEK293, His-Avi) is 377 a.a., with molecular weight of 50-60 kDa.

HY-P77585

	Carbonic Anhydrase 9 Protein, Mouse (HEK293, His) CA9; CAIX; CA-IX; EC 4.2.1.1; G250; MN; P54/58N; PMW1; RCC	Mouse	HEK293
	The Carbonic Anhydrase 9 protein is responsible for catalyzing the interconversion between carbon dioxide and water, as well as facilitating the conversion of carbonic acid into its dissociated ions, namely bicarbonate and hydrogen ions. Carbonic Anhydrase 9 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-His labeled tag. The total length of Carbonic Anhydrase 9 Protein, Mouse (HEK293, His) is 359 a.a., with molecular weight of 50-53 kDa.

HY-P71720

	CA12/Carbonic Anhydrase 12 Protein, Human (P.pastoris, His) CA 12; CA XII; CA12; Carbonic anhydrase XII; Carbonic dehydratase; CAXII; FLJ20151; HsT18816; T18816; Tumor antigen HOM RCC 3.1.3; Tumor antigen HOM-RCC-3.1.3	Human	P. pastoris
	CA12 (or carbonic anhydrase 12) plays a crucial role in the reversible hydration of carbon dioxide, catalyzing its conversion into bicarbonate ions and protons. This enzymatic activity is essential for key physiological processes, including regulating pH and maintaining acid-base balance. CA12/Carbonic Anhydrase 12 Protein, Human (P.pastoris, His) is the recombinant human-derived CA12/Carbonic Anhydrase 12 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of CA12/Carbonic Anhydrase 12 Protein, Human (P.pastoris, His) is 277 a.a., with molecular weight of ~33.1 kDa.

HY-P701527

	HERC2 Protein, Human (His) HERC2; E3 ubiquitin-protein ligase HERC2; HECT domain and RCC1-like domain-containing protein 2; HECT-type E3 ubiquitin transferase HERC2	Human	E. coli
	The HERC2 protein is an E3 ubiquitin protein ligase that tightly regulates ubiquitin-dependent retention of repair proteins on damaged chromosomes, especially in response to ionizing radiation (IR). HERC2 is recruited to DNA damage sites and promotes the assembly of UBE2N and RNF8, promoting "Lys-63" linked ubiquitin chains to produce DNA damage-induced responses. HERC2 Protein, Human (His) is the recombinant human-derived HERC2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of HERC2 Protein, Human (His) is 371 a.a., .

HY-P75454

	Carbonic Anhydrase 9 Protein, Canine (HEK293, His) Carbonic anhydrase 9; CA-IX; P54/58N; pMW1; CA9; G250; MN	Canine	HEK293
	The carbonic anhydrase 9 (CA9) protein plays a crucial role as a catalyst in the conversion of carbon dioxide and water. It promotes the formation of bicarbonate and hydrogen ions (dissociated ions of carbonic acid). Carbonic Anhydrase 9 Protein, Canine (HEK293, His) is the recombinant canine-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-His labeled tag. The total length of Carbonic Anhydrase 9 Protein, Canine (HEK293, His) is 373 a.a., with molecular weight of ~50 kDa.

HY-P75455

	Carbonic Anhydrase 9 Protein, Canine (HEK293, hFc) Carbonic anhydrase 9; CA-IX; P54/58N; pMW1; CA9; G250; MN	Canine	HEK293
	The carbonic anhydrase 9 (CA9) protein plays a crucial role as a catalyst in the conversion of carbon dioxide and water. It promotes the formation of bicarbonate and hydrogen ions (dissociated ions of carbonic acid). Carbonic Anhydrase 9 Protein, Canine (HEK293, hFc) is the recombinant canine-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Carbonic Anhydrase 9 Protein, Canine (HEK293, hFc) is 373 a.a., with molecular weight of ~79 kDa.

HY-P72863

	Carbonic Anhydrase 9 Protein, Human (HEK293, Fc) Carbonic anhydrase 9; CA-IX; P54/58N; pMW1; CA9; G250; MN	Human	HEK293
	The carbonic anhydrase 9 (CA9) protein plays a crucial role as a catalyst in the conversion of carbon dioxide and water. It promotes the formation of bicarbonate and hydrogen ions (dissociated ions of carbonic acid). Carbonic Anhydrase 9 Protein, Human (HEK293, Fc) is the recombinant human-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Carbonic Anhydrase 9 Protein, Human (HEK293, Fc) is 377 a.a., with molecular weight of ~67.4 kDa.


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(Rac)-Apremilast-d5
(Rac)-Apremilast-d₅ is a deuterium labeled (R)-Apremilast. (R)-Apremilast ((R)-CC-10004) is a enantiomer of Apremilast[1].

Cat. No.	Product Name	Application	Reactivity

HY-P82897

RCC1 Antibody (YA2642)

RCC1; RCC1-I; SNHG3-RCC1; CHC1
WB, IHC-P, ICC/IF, IP, FC Human, Mouse, Rat

HY-P81623

CA9 Antibody (YA1368) CA9; G250; MN; Carbonic anhydrase 9; Carbonate dehydratase IX; Carbonic anhydrase IX; CA-IX; CAIX; Membrane antigen MN; P54/58N; Renal cell carcinoma-associated antigen G250; RCC-associated antigen G250; pMW1	FC, ELISA	Human

HY-P82698

Carbonic Anhydrase 9Rabbit mAb Antibody (YA2443) CA9; G250; MN; Carbonic anhydrase 9; Carbonate dehydratase IX; Carbonic anhydrase IX; CA-IX; CAIX; Membrane antigen MN; P54/58N; Renal cell carcinoma-associated antigen G250; RCC-associated antigen G250; pMW1	IHC-P	Human

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