RNS

By Targets:	Apoptosis (1) Bacterial (2) Endogenous Metabolite (1) Fluorescent Dye (2) MDM-2/p53 (1) Mitochondrial Metabolism (1) Nucleoside Antimetabolite/Analog (1) Reactive Oxygen Species (8)
By Research Areas:	Cancer (3) Infection (1) Inflammation/Immunology (4)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-123533

Resorufin

NSC 12097
Reactive Oxygen Species Others

Resorufin (NSC 12097) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte .

Resorufin NSC 12097	Reactive Oxygen Species	Others
Resorufin (NSC 12097) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte .

HY-123533A

Resorufin sodium salt NSC 12097 sodium salt	Reactive Oxygen Species	Others
Resorufin sodium salt (NSC 12097 sodium salt) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte .

HY-123533S

Resorufin-d6 NSC 12097-d₆	Reactive Oxygen Species	Others
Resorufin-d₆ is the deuterium labeled Resorufin. Resorufin (NSC 12097) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte[1].

HY-111646

N6-Etheno 2'-deoxyadenosine	Nucleoside Antimetabolite/Analog Endogenous Metabolite	Inflammation/Immunology
N6-Etheno 2'-deoxyadenosine is a reactive oxygen species (ROS)/reactive nitrogen species (RNS)-induced DNA oxidation product, used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues .

HY-123894

Pelargonidin 3,5-diglucoside chloride	Reactive Oxygen Species	Inflammation/Immunology
Pelargonidin 3,5-diglucoside (chloride) is a natural pigment abundantly present in red fruits and vegetables. Pelargonidin 3,5-diglucoside (chloride) acts as a scavenger for reactive oxygen species and reactive nitrogen species . Pelargonidin 3,5-diglucoside (chloride) demonstrates inhibitory effects on enzymes involved in the production of ROS, *RNS*, and pro-inflammatory cytokines .

HY-151925

Antibacterial agent 126	Bacterial	Infection
Antibacterial agent 126 is a potent antibacterial agent. Antibacterial agent 126 reduces the burden of biofilm to avoid developing agent resistance. Antibacterial agent 126 disturbs the membrane integrity and leads to the leakage of intracellular materials. Antibacterial agent 126 increase in ROS and reactive nitrogen species (RNS) production .

HY-126849

3-Morpholinosydnonimine SIN-1; Linsidomine	MDM-2/p53	Cancer
3-Morpholinosydnonimine (SIN-1; Linsidomine) is a spontaneous *ROS/RNS* generator and a peroxynitrite donor. 3-Morpholinosydnonimine inhibits hypertrophic chondrocytes activity and induces necrosis. 3-Morpholinosydnonimine induces p53-dependent apoptosis, induces p53 accumulation and activates MAPK phosphorylation .

HY-125859A

Myeloperoxidase, human white blood cells MPO	Bacterial	Inflammation/Immunology
Myeloperoxidase, human white blood cells (MPO) is a peroxidase. In Myeloperoxidase, human white blood cells mediate oxidative stress by promoting the production of reactive oxygen species (ROS) and active nitrogen (RNS), regulating the polarization and inflammation-related signaling pathways of microglia and neutrophils. Myeloperoxidase, human white blood cells has antibacterial activity .

HY-N9534

Xylopine	Reactive Oxygen Species Apoptosis	Cancer
Xylopine is an aporphine alkaloid with cytotoxic activity on cancer cells. Xylopine induces oxidative stress, causes G2/M cell cycle arrest and apoptosis in cancer cells .

HY-D1055

MitoSOX Red 20+ Cited Publications	Fluorescent Dye Reactive Oxygen Species Mitochondrial Metabolism	Cancer
MitoSOX Red is a live cell fluorescent probe that specifically targets mitochondria and is cell membrane permeable. MitoSOX Red enters mitochondria and is oxidized by superoxide but not by other ROS or RNS generating systems. The oxidized MitoSOX Red then binds to nucleic acids in mitochondria/nucleus, producing strong red fluorescence. MitoSOX Red can be used as a fluorescent indicator to specifically detect superoxide. In addition, superoxide dismutase (SOD) can prevent the oxidation of MitoSOX Red. Excitation/emission wavelength: 510/580 nm.

HY-108537

L 012 sodium salt	Reactive Oxygen Species	Inflammation/Immunology
L 012 sodium salt a luminol-based chemiluminescent (CL) probe, is widely used in vitro and in vivo to detect NADPH oxidase (Nox)-derived superoxide (O2 ^•−) and identify Nox inhibitors .

HY-D1157

HKPerox-2 1 Publications Verification	Fluorescent Dye Reactive Oxygen Species	Others
HKPerox-2 is a highly sensitive green fluorescent probe for the specific detection of H₂O₂ in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .

Cat. No.	Product Name	Type

HY-123533

Resorufin

NSC 12097
Fluorescent Dyes/Probes

Resorufin (NSC 12097) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte .

Resorufin NSC 12097	Fluorescent Dyes/Probes
Resorufin (NSC 12097) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte .

HY-123533A

Resorufin sodium salt NSC 12097 sodium salt	Fluorescent Dyes/Probes
Resorufin sodium salt (NSC 12097 sodium salt) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte .

HY-D1055

MitoSOX Red 20+ Cited Publications	Fluorescent Dyes/Probes
MitoSOX Red is a live cell fluorescent probe that specifically targets mitochondria and is cell membrane permeable. MitoSOX Red enters mitochondria and is oxidized by superoxide but not by other ROS or RNS generating systems. The oxidized MitoSOX Red then binds to nucleic acids in mitochondria/nucleus, producing strong red fluorescence. MitoSOX Red can be used as a fluorescent indicator to specifically detect superoxide. In addition, superoxide dismutase (SOD) can prevent the oxidation of MitoSOX Red. Excitation/emission wavelength: 510/580 nm.

MitoSOX Red

20+ Cited Publications

Fluorescent Dyes/Probes

MitoSOX Red is a live cell fluorescent probe that specifically targets mitochondria and is cell membrane permeable. MitoSOX Red enters mitochondria and is oxidized by superoxide but not by other ROS or RNS generating systems. The oxidized MitoSOX Red then binds to nucleic acids in mitochondria/nucleus, producing strong red fluorescence. MitoSOX Red can be used as a fluorescent indicator to specifically detect superoxide. In addition, superoxide dismutase (SOD) can prevent the oxidation of MitoSOX Red.
Excitation/emission wavelength: 510/580 nm.

HY-108537

L 012 sodium salt	Dyes
L 012 sodium salt a luminol-based chemiluminescent (CL) probe, is widely used in vitro and in vivo to detect NADPH oxidase (Nox)-derived superoxide (O2 ^•−) and identify Nox inhibitors .

HY-D1157

HKPerox-2 1 Publications Verification	Fluorescent Dyes/Probes
HKPerox-2 is a highly sensitive green fluorescent probe for the specific detection of H₂O₂ in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-111646

N6-Etheno 2'-deoxyadenosine	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Nucleoside Antimetabolite/Analog Endogenous Metabolite
N6-Etheno 2'-deoxyadenosine is a reactive oxygen species (ROS)/reactive nitrogen species (RNS)-induced DNA oxidation product, used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues .

HY-N9534

Xylopine	Alkaloids other families Classification of Application Fields Source classification Plants Isoquinoline Alkaloids Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis
Xylopine is an aporphine alkaloid with cytotoxic activity on cancer cells. Xylopine induces oxidative stress, causes G2/M cell cycle arrest and apoptosis in cancer cells .

HY-123894

Pelargonidin 3,5-diglucoside chloride	Structural Classification Anthocyans Flavonoids Source classification Hyacinthus orientalis L. Sp. Pl. Plants Asparagaceae Juss.	Reactive Oxygen Species
Pelargonidin 3,5-diglucoside (chloride) is a natural pigment abundantly present in red fruits and vegetables. Pelargonidin 3,5-diglucoside (chloride) acts as a scavenger for reactive oxygen species and reactive nitrogen species . Pelargonidin 3,5-diglucoside (chloride) demonstrates inhibitory effects on enzymes involved in the production of ROS, *RNS*, and pro-inflammatory cytokines .

Species:	Human (5)
Tag:	His (5) Myc (1)
Source:	HEK293 (5)

Cat. No.	Compare	Product Name	Species	Source

HY-P70538

Rnase 3 Protein, Human (HEK293, His)

Eosinophil Cationic Protein; ECP; Ribonuclease 3; RNase 3; RNASE3; ECP; RNS3
Human HEK293

HY-P71677

	FAM20C Protein, Human (HEK293, Myc, His) C76981; Dentin matrix protein 4; Family with sequence similarity 20 member C; GEF CK; Golgi enriched fraction casein kinase; Protein FAM20C; RNS	Human	HEK293
	The FAM20C protein is a Golgi kinase that phosphorylates secretory pathway proteins and contributes to the biomineralization of bones and teeth. FAM20C phosphorylates caseins and proteins involved in biomineralization and also affects lipid homeostasis, wound healing, and cell migration and adhesion. FAM20C Protein, Human (HEK293, Myc, His) is the recombinant human-derived FAM20C protein, expressed by HEK293 , with N-His, C-Myc labeled tag. The total length of FAM20C Protein, Human (HEK293, Myc, His) is 492 a.a., with molecular weight of ~61.4 kDa.

HY-P71261

	RNASE6 Protein, Human (HEK293, His) Ribonuclease K6; RNase K6; RNASE6; RNS6	Human	HEK293
	RNASE6 Protein, a pyrimidine-preferring ribonuclease, exhibits potent antibacterial activity against diverse bacteria, including P. aeruginosa, A. baumanii, and E. coli. Its effect is independent of ribonuclease activity, inducing bacterial membrane disruption and Gram-negative bacteria agglutination, emphasizing its bactericidal properties. RNASE6's robust antibacterial activity suggests a potential role in preserving urinary tract sterility. RNASE6 Protein, Human (HEK293, His) is the recombinant human-derived RNASE6 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of RNASE6 Protein, Human (HEK293, His) is 127 a.a., with molecular weight of ~22.0 kDa.

HY-P71089

	Rnase 1 Protein, Human (HEK293, His) Ribonuclease Pancreatic; HP-Rnase; RIB-1; RNase UpI-1; Ribonuclease 1; RNase 1; Ribonuclease A; RNase A; RNASE1; RIB1; RNS1	Human	HEK293
	The RNase 1 protein functions as an endonuclease capable of catalyzing RNA cleavage specific to the 3' side of pyrimidine nucleotides. This enzymatic activity extends to single- and double-stranded RNA, demonstrating its versatility in RNA substrate recognition and processing. Rnase 1 Protein, Human (HEK293, His) is the recombinant human-derived Rnase 1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Rnase 1 Protein, Human (HEK293, His) is 128 a.a., with molecular weight of 21-28 kDa.

HY-P71089Y

	Rnase 1 Protein, Human (HEK293, His, solution) Ribonuclease Pancreatic; HP-Rnase; RIB-1; RNase UpI-1; Ribonuclease 1; RNase 1; Ribonuclease A; RNase A; RNASE1; RIB1; RNS1	Human	HEK293
	The RNase 1 protein functions as an endonuclease capable of catalyzing RNA cleavage specific to the 3' side of pyrimidine nucleotides. This enzymatic activity extends to single- and double-stranded RNA, demonstrating its versatility in RNA substrate recognition and processing. Rnase 1 Protein, Human (HEK293, His, solution) is the recombinant human-derived Rnase 1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Rnase 1 Protein, Human (HEK293, His, solution) is 128 a.a., with molecular weight of 18-28 kDa.


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Cat. No.	Product Name	Chemical Structure

HY-123533S

Resorufin-d6

Resorufin-d₆ is the deuterium labeled Resorufin. Resorufin (NSC 12097) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte[1].

Resorufin-d6
Resorufin-d₆ is the deuterium labeled Resorufin. Resorufin (NSC 12097) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte[1].

Cat. No.	Product Name	Application	Reactivity

HY-P82569

RNase L Antibody (YA2314)

PRCA1; Ribonuclease4; RibonucleaseL; RNase L; Rnasel; RNS4
WB Human
HY-P81954

ABCE1 Antibody (YA1699)

ABC38; ABCE1; HuHP68; OABP; RLI; RNASEL1; RNASELI; RNS4I
WB, IP Human, Mouse, Rat

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Fluorescent Dye

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Recombinant Proteins

Isotope-Labeled Compounds

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