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Results for "

ROR

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ROR (72) ADC Antibody (1) Antibody-Drug Conjugates (ADCs) (1) Apoptosis (4) Autophagy (1) Dihydroorotate Dehydrogenase (3) Endogenous Metabolite (1) Fluorescent Dye (2) FXR (1) Interleukin Related (2) LXR (1) Reactive Oxygen Species (1) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (25) Cardiovascular Disease (1) Inflammation/Immunology (51) Metabolic Disease (2) Neurological Disease (6)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Antibodies

Targets Recommended: ROR

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-RS12124

ROR1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ROR1 Human Pre-designed siRNA Set A contains three designed siRNAs for ROR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ROR1 Human Pre-designed siRNA Set A ROR1 Human Pre-designed siRNA Set A

HY-RS12125

ROR2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ROR2 Human Pre-designed siRNA Set A contains three designed siRNAs for ROR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ROR2 Human Pre-designed siRNA Set A ROR2 Human Pre-designed siRNA Set A

HY-128353

ROR agonist-1	ROR	Inflammation/Immunology
ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), inhibition of IL-17A production from human primary T_H 17 cells with a pIC₅₀ of 7.5 .

HY-D2293

RORγ allosteric probe-1	ROR Fluorescent Dye	Others
RORγ allosteric probe-1 (Compound 12h) is a RORγ allosteric fluorescent probe (Ex/Em: 490/524 nm). RORγ allosteric probe-1 can be used for exploration of RORγ allosteric inhibitors and RORγ function .

HY-142934

RORγt inhibitor 2	ROR	Inflammation/Immunology Cancer
RORγt inhibitor 2 (Compound 119) is a potent RORγt inhibitor with an IC₅₀ of 9.2 nM. RORγt inhibitor 2 can be used for the research of cancer, inflammation or autoimmune diseases mediated by RORγt .

HY-126321

RORγt agonist 1	ROR	Cancer
RORγt agonist 1 (compound 14) is a potent, orally bioavailable RORγt agonist with an EC₅₀ of 20.8 nM. RORγt agonist 1 showes high metabolic stability, improved aqueous solubility and excellent mouse PK profile. RORγt agonist 1 is a potential candidate of RORγt agonist for cancer immunotherapy .

HY-122737

RORγt Inverse agonist 8	ROR	Inflammation/Immunology
RORγt Inverse agonist 8 is a potent, selective, orally bioavailable RORγt inverse agonist, with an IC₅₀ of 19 nM for human RORγt-LBD .

HY-49076

RORγ inverse agonist 1

ROR Cancer

RORγ inverse agonist 1 is the inverse agonist of RORγ .

RORγ inverse agonist 1	ROR	Cancer
RORγ inverse agonist 1 is the inverse agonist of RORγ .

HY-147533

RORγt inverse agonist 30	ROR	Inflammation/Immunology
RORγt inverse agonist 30 (Compound 1) is a potent RORγt inverse agonist with the IC₅₀ of 46 nM. Targeting the nuclear receptor RORγt is effective in autoimmune disorders .

HY-142296

RORγt inhibitor 1

ROR Inflammation/Immunology

RORγt inhibitor 1 is a RORγt allosteric inhibitor with an IC₅₀ value of 1 nM.

RORγt inhibitor 1	ROR	Inflammation/Immunology
RORγt inhibitor 1 is a RORγt allosteric inhibitor with an IC₅₀ value of 1 nM.

HY-160021

RORγt agonist 4	ROR	Inflammation/Immunology
RORγt agonist 4 (compound 14) is a potent and selective agonist of RORγt. RORγt agonist 4 significantly enhances metabolic stability. RORγt agonist 4 improves the situation of tumor models of mouse B16F10 melanoma and LLC lung adenocarcinoma .

HY-142834

RORγt/DHODH-IN-2	ROR Dihydroorotate Dehydrogenase	Inflammation/Immunology
RORγt/DHODH-IN-2 (compound 1) is a potent dual RORγt/DHODH inhibitor. RORγt/DHODH-IN-2 can be used for inflammatory bowel disease (IBD) research .

HY-132900

RORγ agonist 1

ROR Cancer

RORγ agonist 1 is a potent and orally bioavailable RORγ agonist (EC₅₀ = 21 nM) with antitumor activity.

RORγ agonist 1	ROR	Cancer
RORγ agonist 1 is a potent and orally bioavailable RORγ agonist (EC₅₀ = 21 nM) with antitumor activity.

HY-142940

RORγt modulator 5	ROR	Inflammation/Immunology
RORγt modulator 5 is a RORγt modulator with a K_i value of <100 nM. RORγt modulator 5 has the potential for inflammatory, metabolic, autoimmune and other diseases mediated by RORy study (WO2017132432A1; compound 2) .

HY-111748

RORγt Inverse agonist 2

ROR Inflammation/Immunology

RORγt Inverse agonist 2 is a selective, orally active RORγt inverse agonist with an EC₅₀ of 119 nM .

RORγt Inverse agonist 2	ROR	Inflammation/Immunology
RORγt Inverse agonist 2 is a selective, orally active RORγt inverse agonist with an EC₅₀ of 119 nM .

HY-142806

RORγt inverse agonist 26	ROR	Inflammation/Immunology
RORγt inverse agonist 26 is a potent reverse agonist of RORγt. RORγt inverse agonist 26 regulates the differentiation of Th17 cells and inhibits the production of IL-17. RORγt inverse agonist 26 has the potential for the research of inflammation and autoimmune diseases (extracted from patent WO2021228215A1, compound 1) .

HY-142703

RORγt inverse agonist 28	ROR	Inflammation/Immunology
RORγt inverse agonist 28 is a potent reverse agonist of RORγt. RORγt inverse agonist 28 regulates the differentiation of Th17 cells and inhibits the production of IL-17. RORγt inverse agonist 28 has the potential for the research of inflammation and autoimmune diseases (extracted from patent WO2021228215A1, compound 6) .

HY-142939

RORγt modulator 4	ROR	Inflammation/Immunology Cancer
RORγt modulator 4 is a RORγt modulator. RORγt modulator 4 has an activity to modulate IL-17A production in cells derived from mouse spleen (WO2018030550A1; compound 146) .

HY-143271

RORγt inverse agonist 29	ROR	Inflammation/Immunology
RORγt inverse agonist 29 is a potent, orally active and selective RORγt inverse agonist (IC₅₀: 21 nM). RORγt inverse agonist 29 can be used in the research of skin inflammation and autoimmune diseases like psoriasis .

HY-132195

RORγt inverse agonist 14	ROR	Inflammation/Immunology
RORγt inverse agonist 14 (8e) is a potent, orally active and selective RORγt inverse agonist (EC₅₀ of 2.5 nM) with anti-inflammatory activity. RORγt inverse agonist 14 is used in the study for rheumatoid arthritis and psoriasis .

HY-142938

RORγt agonist 3	ROR	Inflammation/Immunology
RORγt agonist 3 is a potent agonist of RORγt. RORγt agonist 3 promotes the differentiation of Th17 cells and enhances the levels of pro-inflammatory cytokines, thereby increasing the cytotoxicity of lymphocytes. RORγt agonist 3 inhibits the production of regulatory T cells, which suppresses the immune response (extracted from patent WO2021136326A1, compound 23) .

HY-142937

RORγt agonist 2	ROR	Inflammation/Immunology
RORγt agonist 2 is a potent agonist of RORγt. RORγt agonist 2 promotes the differentiation of Th17 cells and enhances the levels of pro-inflammatory cytokines, thereby increasing the cytotoxicity of lymphocytes. RORγt agonist 2 inhibits the production of regulatory T cells, which suppresses the immune response (extracted from patent WO2021136339A1, compound 17) .

HY-128573

RORγt Inverse agonist 3	ROR	Neurological Disease
RORγt Inverse agonist 3 is a potent, selective and orally active RORγ inverse agonist, with EC₅₀s of 0.22 μM and 0.15 μM for hRORγ and RORγt (human IL-17 cells), respectively .

HY-155542

RORγ antagonist 1	ROR	Cancer
RORγ antagonist 1 (compound 22), a potent betulinic acid derivative, is an antagonist of RORγ (K_D=0.18 μM). RORγ antagonist 1 exhibits anti-proliferative activity in HPAF-II pancreatic cancer xenograft model. RORγ antagonist 1 inhibits RAS/MAPK and AKT/mTORC1 pathway, and induces caspase-dependent apoptosis in pancreatic cancer cells .

HY-142847

RORγt/DHODH-IN-3	ROR Dihydroorotate Dehydrogenase	Inflammation/Immunology
RORγt/DHODH-IN-3 (compound (S)-14d) is a dual RORγt/DHODH inhibitor, with IC₅₀s of 0.098 μM and 0.432 μM, respectively. RORγt/DHODH-IN-3 exhibits remarkable in vivo anti-inflammatory activity .

HY-130243

RORγt Inverse agonist 6	ROR	Inflammation/Immunology
RORγt Inverse agonist 6 (compound 43) is a RORγt inverse agonist for the study of Th17-driven autoimmune diseases. RORγt Inverse agonist 6 (compound 43) suppresses IL-17A gene expression by IL-23 stimulation in vivo .

HY-142843

RORγt/DHODH-IN-1	ROR Dihydroorotate Dehydrogenase	Inflammation/Immunology
RORγt/DHODH-IN-1 (compound (R)-14d) is a potent and orally active dual RORγt/DHODH inhibitor, with IC₅₀s of 0.083 μM and 0.172 μM, respectively. RORγt/DHODH-IN-1 exhibits remarkable in vivo anti-inflammatory activity .

HY-142936

RORγt modulator 3	ROR	Neurological Disease Inflammation/Immunology Cancer
RORγt modulator 3 (Compound 23) is a modulator of retinoid-related orphan receptor γt (RORγt). RORγt modulator 3 can be used for the research of RORyt mediated diseases such as, e.g., pain, inflammation, COPD, asthma, rheumatoid arthritis, colitis, multiple sclerosis, psoriasis, neurodegenerative diseases and cancer .

HY-155548

RORγt inverse agonist 31	ROR	Inflammation/Immunology
RORγt inverse agonist 31 (14g) is a potent *retinoic acid receptor-related orphan receptor γt (RORγt)* inverse agonist, with an IC₅₀ of 0.428 μM. RORγt inverse agonist 31 can alleviate the severity of Imiquimod (HY-B0180)-induced psoriasis in mice .

HY-142935

RORγt modulator 2	ROR	Neurological Disease Inflammation/Immunology Cancer
RORγt modulator 2 (Compound 21) is a modulator of retinoid-related orphan receptor γt (RORγt) with the IC₅₀ of <50 nM. RORγt modulator 2 can be used for the research of RORyt mediated diseases such as, e.g., pain, inflammation, COPD, asthma, rheumatoid arthritis, colitis, multiple sclerosis, psoriasis, neurodegenerative diseases and cancer .

HY-131338

RORγt inverse agonist 13	ROR	Inflammation/Immunology
RORγt inverse agonist 13 (Compound 3i) is a potent, orally active and selective RORγt inverse agonist, with improved agent-like properties, with an IC₅₀ of 63.8 nM .

HY-133552

RORγt Inverse agonist 10	ROR	Inflammation/Immunology
RORγt Inverse agonist 10 is a potent and orally bioavailable RORγt (retinoic acid receptor-related orphan nuclear receptor gamma t) inverse agonist, with an IC₅₀ of 51 nM. RORγt is a major transcription factor of genes related to psoriasis pathogenesis such as IL-17A, IL-22, and IL-23R

HY-139847

RORγt inverse agonist 23	ROR	Inflammation/Immunology
RORγt inverse agonist 23 is a potent, selective, and orally available novel retinoic acid receptor-related orphan receptor γt inverse agonist.

HY-14422

SR1078 10+ Cited Publications	ROR	Cancer
SR1078 is a selective agonist of retinoic acid receptor-related orphan receptor α/γ (*RORα/RORγ). SR1078 directly binds to the ligand binding domain of RORα and RORγ and increases the transcriptional activity of these receptors, leading to stimulation of ROR*α/γ target gene transcription .

HY-13421

SR1001

5 Publications Verification

ROR Inflammation/Immunology

SR1001 is a selective RORα and RORγt inverse agonist with K_is 172 and 111 nM, respectively.
HY-14413

SR3335

5+ Cited Publications

ML 176
ROR Metabolic Disease

SR3335 (ML 176) is a selective RORα inverse agonist that directly binds to RORα with a K_i of 220 nM .

SR1001 5 Publications Verification	ROR	Inflammation/Immunology
SR1001 is a selective RORα and RORγt inverse agonist with K_is 172 and 111 nM, respectively.

SR3335 5+ Cited Publications ML 176	ROR	Metabolic Disease
SR3335 (ML 176) is a selective RORα inverse agonist that directly binds to RORα with a K_i of 220 nM .

HY-120210

XY018	ROR	Inflammation/Immunology Cancer
XY018 is a potent *ROR-γ*-selective antagonist. XY018 inhibits ROR-γ constitutive activity in 293T cells with high potency (EC₅₀, 190 nM). XY018 binds to the ROR-γ hydrophobic ligand binding domain (LBD) .

HY-102075B

TMP780	ROR	Inflammation/Immunology
TMP780 is an inverse agonist of RORγt with an IC₅₀ of 13 nM. RORγt is a tractable agent target for the treatment of cutaneous inflammatory disorders .

HY-P99201

Zilovertamab

UC-961; Cirmtuzumab
ROR Cancer

Zilovertamab (UC-961) is a humanised monoclonal antibody against ROR1 that blocks Wnt5a-induced ROR1 signalling .

Zilovertamab UC-961; Cirmtuzumab	ROR	Cancer
Zilovertamab (UC-961) is a humanised monoclonal antibody against *ROR1* that blocks Wnt5a-induced ROR1 signalling .

HY-111509

TAK-828F	ROR	Inflammation/Immunology
TAK-828F is a potent, selective, and orally available retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonist (binding IC₅₀=1.9 nM, reporter gene IC₅₀=6.1 nM). TAK-828F shows excellent RORγt isoforms selectivity (>5000-fold selectivity against human RORα and RORβ) .

HY-119366

S18-000003	ROR	Inflammation/Immunology
S18-000003 is a potent, selective and orally active inhibitor of *retinoic acid receptor-related orphan receptor-gamma-t (RORγt), with an IC₅₀* of <30 nM towards human RORγt in competitive binding assays. S18-000003 shows selectivity for RORγt over other ROR family members (IC₅₀>10 μM). S18-000003 can be used for the research of psoriasis with low risk of thymic aberrations .

HY-19770

GSK2981278 3 Publications Verification	ROR	Inflammation/Immunology
GSK2981278 is a potent and selective RORγ inverse agonist. GSK2981278 inhibits activation of the il17 promoter and interferes RORγ-DNA binding .

HY-117819

TMP920

ROR Inflammation/Immunology

TMP920 is a highly potent and selective RORγt antagonist. TMP920 inhibits RORγt binding to the SRC1 peptide with an IC₅₀ of 0.03 μM .

TMP920	ROR	Inflammation/Immunology
TMP920 is a highly potent and selective RORγt antagonist. TMP920 inhibits RORγt binding to the SRC1 peptide with an IC₅₀ of 0.03 μM .

HY-139534

ARI-1	ROR Apoptosis	Cancer
ARI-1 is an inhibitor of receptor tyrosine kinase-like orphan receptor 1 (ROR1) inhibitor. ARI-1 effectively inhibits aberrant ROR1 expression, which is associated with the development of non-small cell lung cancer (NSCLC) and EGFR-TKI-induced drug resistance. ARI-1 binds to the extracellular Frizzled domain of ROR1 and regulates PI3K/AKT/mTOR signaling in a ROR1-dependent manner. ARI-1 potently inhibits NSCLC cell proliferation and migration and has antitumor activity in vivo ^{[1] ^.}

HY-126037

(±)-ML 209 1 Publications Verification	ROR	Inflammation/Immunology
(±)-ML 209 (compound 4n), a diphenylpropanamide, is a retinoic acid-related orphan receptor RORγ antagonist with an IC₅₀ of 1.1 μM. (±)-ML 209 inhibits RORγt transcriptional activity with an IC₅₀ of 300 nM in HEK293t cells. (±)-ML 209 inhibits the transcriptional activity of RORγt, but not RORα in cells. (±)-ML 209 selectively inhibits murine Th17 cell differentiation without affecting the differentiation of naïve CD4 ⁺ T cells into other lineages, including Th1 and regulatory T cells .

HY-155487

JTE-151	ROR	Neurological Disease Inflammation/Immunology
JTE-151 is a RORγ inhibitor, which can suppress overactive immune response through inhibition of RORγ related to the activation of Th17 cells, making JTE-151 possible to be used in autoimmune disease research .

HY-102075A

TMP778

ROR Inflammation/Immunology

TMP778 is a potent and selevtive RORγt inverse agonist, with an IC₅₀ of 7 nM in FRET assay.
HY-115777

ARN-6039

ROR Neurological Disease

ARN-6039 is an orally available inverse agonist of RORγ for autoimmune demyelinating disease.

HY-103637

Vimirogant VTP-43742	ROR	Inflammation/Immunology
Vimirogant (VTP-43742) is a potent, selective, and orally active RORγt inhibitor (K_i=3.5 nM; IC₅₀=17 nM). Vimirogant exhibits >1000-fold selectivity versus the RORα and RORβ isotypes. Vimirogant inhibits Th17 differentiation and IL-17A secretion from mouse splenocytes (IC₅₀=57 nM) without affecting Th1, Th2, or Treg cell differentiation. Vimirogant has the potential for autoimmune disorders research .

HY-103637A

Vimirogant hydrochloride VTP-43742 hydrochloride	ROR	Inflammation/Immunology
Vimirogant (VTP-43742) hydrochloride is a potent, selective, and orally active RORγt inhibitor (K_i=3.5 nM; IC₅₀=17 nM). Vimirogant hydrochloride exhibits >1000-fold selectivity versus the RORα and RORβ isotypes. Vimirogant hydrochloride inhibits Th17 differentiation and IL-17A secretion from mouse splenocytes (IC₅₀=57 nM) without affecting Th1, Th2, or Treg cell differentiation. Vimirogant hydrochloride has the potential for autoimmune disorders research .

Species:	Human (11) Rat (1) Mouse (1) Canine (1)
Tag:	His (12) Tag Free (1) Avi (4) Fc (1)
Source:	HEK293 (11) Sf9 insect cells (1) Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P78617

	ROR1 Protein, Rat (HEK293, His) ROR1; NTRKR1	Rat	HEK293
	ROR1 Protein, a crucial member of the Tyr protein kinase family within the protein kinase superfamily, plays a key role in cellular signaling and regulation as a tyrosine kinase. Its classification emphasizes its significance in phosphorylation events, sharing conserved features with related kinases. Studying ROR1 contributes to understanding its unique enzymatic functions and potential therapeutic applications. Further exploration promises insights into its broader impact on cellular signaling pathways and contributions to normal physiology and pathological conditions. ROR1 Protein, Rat (HEK293, His) is the recombinant rat-derived ROR1 protein, expressed by HEK293, with C-10*His labeled tag. The total length of ROR1 Protein, Rat (HEK293, His) is 374 a.a., with molecular weight of 60-75 kDa.

HY-P73390

	ROR1 Protein, Human (sf9, His) Inactive tyrosine-protein kinase transmembrane receptor ROR1; ROR1; NTRKR1	Human	Sf9 insect cells
	ROR1 protein's minimal kinase activity in vitro suggests an improbable role as a tyrosine kinase in vivo. It serves as a receptor for WNT5A, activating NFkB signaling and potentially inhibiting WNT3A signaling. Notably, ROR1 plays a vital role in the inner ear, facilitating innervation of auditory hair cells by spiral ganglion neurons. ROR1 Protein, Human (sf9, His) is the recombinant human-derived ROR1 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of ROR1 Protein, Human (sf9, His) is 331 a.a., with molecular weight of 55-70 kDa.

HY-P77826

	ROR2 Protein, Human (HEK293, Fc) BDB; BDB1; NTRKR2; ROR2	Human	HEK293
	The ROR2 protein is a tyrosine protein kinase receptor that plays a critical role in early chondrocyte formation and is essential for cartilage and growth plate development. Phosphorylated YWHAB induces osteogenesis and bone formation. ROR2 Protein, Human (HEK293, Fc) is the recombinant human-derived ROR2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ROR2 Protein, Human (HEK293, Fc) is 370 a.a., with molecular weight of 80-110 kDa.

HY-P77827

	ROR2 Protein, Human (HEK293, His-Avi) BDB; BDB1; NTRKR2; ROR2	Human	HEK293
	The ROR2 protein is a tyrosine protein kinase receptor that plays a critical role in early chondrocyte formation and is essential for cartilage and growth plate development. Phosphorylated YWHAB induces osteogenesis and bone formation. ROR2 Protein, Human (HEK293, His-Avi) is the recombinant human-derived ROR2 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of ROR2 Protein, Human (HEK293, His-Avi) is 370 a.a., with molecular weight of 54-58 kDa.

HY-P77825

	ROR1 Protein, Canine (HEK293, His) ROR1; NTRKR1; dJ537F10.1	Canine	HEK293
	ROR1 protein is an important member of the Tyr protein kinase family in the protein kinase superfamily and plays a key role as a tyrosine kinase in cell signaling and regulation. Its classification emphasizes its importance in phosphorylation events and shares conserved features with related kinases. ROR1 Protein, Canine (HEK293, His) is the recombinant canine-derived ROR1 protein, expressed by HEK293 , with C-His labeled tag. The total length of ROR1 Protein, Canine (HEK293, His) is 456 a.a., with molecular weight of 65-68 kDa.

HY-P77828

	ROR2 Protein, Human (Biotinylated, HEK293, His-Avi) BDB; BDB1; NTRKR2; ROR2	Human	HEK293
	The ROR2 protein is a tyrosine protein kinase receptor that plays a critical role in early chondrocyte formation and is essential for cartilage and growth plate development. Phosphorylated YWHAB induces osteogenesis and bone formation. ROR2 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived ROR2 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of ROR2 Protein, Human (Biotinylated, HEK293, His-Avi) is 370 a.a., with molecular weight of 54-65 kDa.

HY-P78032

	ROR1 Protein, Mouse (HEK293, His) ROR1; NTRKR1; dJ537F10.1	Mouse	HEK293
	ROR1 protein shows minimal kinase activity in vitro, indicating an improbable role as a tyrosine kinase in vivo. It functions as a receptor for WNT5A, activating NFkB signaling and potentially inhibiting WNT3A signaling. Additionally, ROR1 plays a vital role in the inner ear, aiding the innervation of auditory hair cells by spiral ganglion neurons. ROR1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived ROR1 protein, expressed by HEK293 , with C-His labeled tag. The total length of ROR1 Protein, Mouse (HEK293, His) is 377 a.a., with molecular weight of 58-68 kDa.

HY-P71263

	ROR2 Protein, Human (HEK293, His) Tyrosine-protein kinase transmembrane receptor ROR2; Neurotrophic tyrosine kinase, receptor-related 2; ROR2; NTRKR2	Human	HEK293
	The ROR2 protein is a tyrosine protein kinase receptor that plays a critical role in early chondrocyte formation and is essential for cartilage and growth plate development. Phosphorylated YWHAB induces osteogenesis and bone formation. ROR2 Protein, Human (HEK293, His) is the recombinant human-derived ROR2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of ROR2 Protein, Human (HEK293, His) is 370 a.a., with molecular weight of 50-60 kDa.

HY-P78510

	ROR1 Protein, Human (HEK293, His-Avi) ROR1; NTRKR1; dJ537F10.1	Human	HEK293
	ROR1 protein's minimal kinase activity in vitro suggests an improbable role as a tyrosine kinase in vivo. It serves as a receptor for WNT5A, activating NFkB signaling and potentially inhibiting WNT3A signaling. Notably, ROR1 plays a vital role in the inner ear, facilitating innervation of auditory hair cells by spiral ganglion neurons. ROR1 Protein, Human (HEK293, His-Avi) is the recombinant human-derived ROR1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of ROR1 Protein, Human (HEK293, His-Avi) is 374 a.a., with molecular weight of 55-70 kDa.

HY-P70732

	ROR1 Protein, Human (HEK293, His) Inactive tyrosine-protein kinase transmembrane receptor ROR1; Neurotrophic tyrosine kinase, receptor-related 1; ROR1; NTRKR1	Human	HEK293
	ROR1 protein's minimal kinase activity in vitro suggests an improbable role as a tyrosine kinase in vivo. It serves as a receptor for WNT5A, activating NFkB signaling and potentially inhibiting WNT3A signaling. Notably, ROR1 plays a vital role in the inner ear, facilitating innervation of auditory hair cells by spiral ganglion neurons. ROR1 Protein, Human (HEK293, His) is the recombinant human-derived ROR1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of ROR1 Protein, Human (HEK293, His) is 374 a.a., with molecular weight of 60-80 kDa.

HY-P71263A

	ROR2 Protein, Human (HEK293, C-His) Tyrosine-protein kinase transmembrane receptor ROR2; Neurotrophic tyrosine kinase, receptor-related 2; ROR2; NTRKR2	Human	HEK293
	The ROR2 protein is a tyrosine protein kinase receptor that plays a critical role in early chondrocyte formation and is essential for cartilage and growth plate development. Phosphorylated YWHAB induces osteogenesis and bone formation. ROR2 Protein, Human (HEK293, C-His) is the recombinant human-derived ROR2 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of ROR2 Protein, Human (HEK293, C-His) is 370 a.a., with molecular weight of ~55 kDa.

HY-P72410

	ROR1 Protein, Human (Biotinylated, HEK293, His-Avi) Inactive tyrosine-protein kinase transmembrane receptor ROR1; Neurotrophictyrosine kinase, receptor-related 1; NTRKR1	Human	HEK293
	ROR1 protein's minimal kinase activity in vitro suggests an improbable role as a tyrosine kinase in vivo. It serves as a receptor for WNT5A, activating NFkB signaling and potentially inhibiting WNT3A signaling. Notably, ROR1 plays a vital role in the inner ear, facilitating innervation of auditory hair cells by spiral ganglion neurons. ROR1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived ROR1 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of ROR1 Protein, Human (Biotinylated, HEK293, His-Avi) is 374 a.a., with molecular weight of 55-80 kDa.

HY-P701400

	RORa Protein, Human (Sf9) RORA; Nuclear receptor ROR-alpha; Nuclear receptor RZR-alpha; Nuclear receptor subfamily 1 group F member 1; RAR-related orphan receptor A; Retinoid-related orphan receptor-alpha	Human	Sf9 insect cells
	The RORa protein is a nuclear receptor that is critical for a variety of physiological processes including development, immunity, circadian rhythms, and metabolic pathways. RORa operates as a monomer, binding DNA to RORE and exhibiting intrinsic transcriptional activity. RORa Protein, Human (Sf9) is the recombinant human-derived RORa protein, expressed by Sf9 insect cells , with tag free. The total length of RORa Protein, Human (Sf9) is 253 a.a., .

HY-P701401

	RORa Protein, Human (Sf9, His) RORA; Nuclear receptor ROR-alpha; Nuclear receptor RZR-alpha; Nuclear receptor subfamily 1 group F member 1; RAR-related orphan receptor A; Retinoid-related orphan receptor-alpha	Human	Sf9 insect cells
	The RORa protein is a nuclear receptor that is critical for a variety of physiological processes including development, immunity, circadian rhythms, and metabolic pathways. RORa operates as a monomer, binding DNA to RORE and exhibiting intrinsic transcriptional activity. RORa Protein, Human (Sf9, His) is the recombinant human-derived RORa protein, expressed by Sf9 insect cells , with N-8*His labeled tag. The total length of RORa Protein, Human (Sf9, His) is 253 a.a., .

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