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Rab7

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Autophagy (1) Endogenous Metabolite (1) Integrin (1) Ras (6) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (5) Infection (1) Inflammation/Immunology (2)

10

Inhibitors & Agonists

1

Peptides

1

Natural
Products

2

Recombinant Proteins

2

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

CID-1067700 5+ Cited Publications ML282	Ras	Inflammation/Immunology
CID-1067700 (ML282) is a pan GTPase inhibitor, and competitively inhibits Ras-related in brain 7 (Rab7) with a K_i of 13 nM.

ML-097 1 Publications Verification CID-2160985	Ras	Cancer
ML-097 (CID-2160985) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, and *Rab7* .

ML-099 2 Publications Verification CID-888706	Ras	Cancer
ML-099 (CID-888706) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, *Rab7, and Rab-2A* .

RAB7A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)
RAB7A Human Pre-designed siRNA Set A contains three designed siRNAs for RAB7A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

RAB7A Human Pre-designed siRNA Set A RAB7A Human Pre-designed siRNA Set A

RAB7B Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)
RAB7B Human Pre-designed siRNA Set A contains three designed siRNAs for RAB7B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

RAB7B Human Pre-designed siRNA Set A RAB7B Human Pre-designed siRNA Set A

HY-19800

ML-098

5+ Cited Publications

CID-7345532
Ras Cancer

ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 with an EC₅₀ of 77.6 nM.

MLS-573151 1 Publications Verification MLS000573151	Ras	Inflammation/Immunology
MLS-573151 (MLS000573151) is a selective GTPase Cdc42 inhibitor with an EC₅₀ of 2 μM. MLS-573151 is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42 .

mP6 Myr-FEEERA-OH	Integrin	Infection
mP6 (Myr-FEEERA-OH) is a myristoylated peptide. mP6 inhibits the interaction of Gα₁₃ with integrin β₃ without disrupting talin-dependent integrin function. mP6 can block the GTP usage of Rac1, Rap1, and Rab7, effectively inhibiting the infection of CHO-A24 cells .

ML141 Maximum Cited Publications 18 Publications Verification CID-2950007	Ras Apoptosis	Cancer
ML141 (CID-2950007) is a potent, allosteric, selective and reversible non-competitive inhibitor of Cdc42 GTPase. ML141 inhibits Cdc42 wild type and Cdc42 Q61L mutant with EC₅₀s of 2.1 and 2.6 μM, respectively. ML141 shows low micromolar potency and selectivity against other members of the Rho family of GTPases (Rac1, Rab2, Rab7). ML141 do not show cytotoxicity in multiple cell lines .

N6-Isopentenyladenosine 1 Publications Verification Riboprine	Autophagy Endogenous Metabolite	Cancer
N6-Isopentenyladenosine (Riboprine), an RNA modification found in cytokinins, which regulate plant growth/differentiation, and a subset of tRNAs, where it improves the efficiency and accuracy of translation. N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with an interesting anti-melanoma activity .

Cat. No.	Product Name	Target	Research Area

mP6 Myr-FEEERA-OH	Integrin	Infection
mP6 (Myr-FEEERA-OH) is a myristoylated peptide. mP6 inhibits the interaction of Gα₁₃ with integrin β₃ without disrupting talin-dependent integrin function. mP6 can block the GTP usage of Rac1, Rap1, and Rab7, effectively inhibiting the infection of CHO-A24 cells .

Species:	Rat (2)
Tag:	His (2)
Source:	E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

	RAB7A Protein, Rat (His) Ras-related protein Rab-7a; Ras-related protein BRL-RAS; Rab7A; Rab7	Rat	E. coli
	RAB7A is a dynamic small GTPase that coordinates endolysosomal trafficking by cycling between a GTP-bound state and a GDP-bound state. In its active state, RAB7A interacts with various effectors, affecting endosomal maturation, microtubule directed migration, and endosome-lysosomal trafficking. RAB7A Protein, Rat (His) is the recombinant rat-derived RAB7A protein, expressed by E. coli , with N-His labeled tag. The total length of RAB7A Protein, Rat (His) is 207 a.a., with molecular weight of ~25.7 kDa.

HY-P75998A

RAB7A Protein, Rat (N-His)

Ras-related protein Rab-7a; Ras-related protein BRL-RAS; Rab7A; Rab7
Rat E. coli

Cat. No.	Product Name	Application	Reactivity

RAB7 Antibody	WB, ICC/IF, IHC-P, FC	Human, Mouse
RAB7 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 23 kDa, targeting to RAB7. It can be used for WB,ICC/IF,IHC-P,FC assays with tag free, in the background of Human, Mouse.

HY-P82053

Rab7B Antibody (YA1798)

Rab7
WB Human

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