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Ras-related

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Ras (3) Aminoacyl-tRNA Synthetase (1)
By Research Areas:	Cancer (3) Inflammation/Immunology (1)

4

Inhibitors & Agonists

14

Recombinant Proteins

10

Antibodies

Targets Recommended: Ras Interleukin Related Mas-related G-protein-coupled Receptor (MRGPR) Trk Receptor ROR NEKs Kallikrein Atg4 CGRP Receptor Atg8/LC3 Arp2/3 Complex ATM/ATR sFRP-1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

CID-1067700 Maximum Cited Publications 6 Publications Verification ML282	Ras	Inflammation/Immunology
CID-1067700 (ML282) is a pan GTPase inhibitor, and competitively inhibits Ras-related in brain 7 (Rab7) with a K_i of 13 nM.

ML-097 1 Publications Verification CID-2160985	Ras	Cancer
ML-097 (CID-2160985) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, and Rab7 .

ML-099 2 Publications Verification CID-888706	Ras	Cancer
ML-099 (CID-888706) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, Rab7, and Rab-2A .

BC-LI-0186	Aminoacyl-tRNA Synthetase	Cancer
BC-LI-0186 is a potent and selective inhibitor of Leucyl-tRNA synthetase (LRS; LeuRS) and Ras-related GTP-binding protein D (RagD) interaction (IC₅₀=46.11 nM). BC-LI-0186 competitively binds to the RagD interacting site of LRS (K_d=42.1 nM) and has on effects on LRS-Vps34, LRS-EPRS, RagB-RagD association, mTORC1 complex formation or the activities of 12 kinases. BC-LI-0186 can effectively suppress the activity of cancer-associated MTOR mutants and the growth of rapamycin-resistant cancer cells. BC-LI-0186 is a promising agent for lung cancer research .

Species:	Human (11) Rat (2) Mouse (1)
Tag:	His (9) Tag Free (2) Strep (1) GST (1) Fc (2)
Source:	HEK293 (5) Sf9 insect cells (1) E. coli (8)

Cat. No.	Compare	Product Name	Species	Source

	RAB7A Protein, Rat (His) Ras-related protein Rab-7a; Ras-related protein BRL-Ras; RAB7A; RAB7	Rat	E. coli
	RAB7A is a dynamic small GTPase that coordinates endolysosomal trafficking by cycling between a GTP-bound state and a GDP-bound state. In its active state, RAB7A interacts with various effectors, affecting endosomal maturation, microtubule directed migration, and endosome-lysosomal trafficking. RAB7A Protein, Rat (His) is the recombinant rat-derived RAB7A protein, expressed by E. coli , with N-His labeled tag. The total length of RAB7A Protein, Rat (His) is 207 a.a., with molecular weight of ~25.7 kDa.

HY-P75998A

RAB7A Protein, Rat (N-His)

Ras-related protein Rab-7a; Ras-related protein BRL-Ras; RAB7A; RAB7
Rat E. coli

	RAB31 Protein, Human (His) Ras-related protein Rab-31; Ras-related protein Rab-22B; RAB31; RAB22B	Human	E. coli
	RAB31 protein binds GDP and GTP and participates in processes like protein transport, insulin response, and receptor internalization. It is mainly located in the early endosome, phagocytic vesicle, and trans-Golgi network membrane. RAB31 is also a biomarker for severe acute respiratory syndrome and is broadly expressed in tissues such as the brain, adrenal glands, and 22 others. RAB31 Protein, Human (His) is the recombinant human-derived RAB31 protein, expressed by E. coli , with N-His labeled tag. The total length of RAB31 Protein, Human (His) is 195 a.a., with molecular weight of ~26 kDa.

HY-P74609

RAB2 Protein, Mouse (His)

Ras-related protein Rab-2A; Rab2A; Rab2
Mouse E. coli

	RAB1B Protein, Human (HEK293, Fc) Ras-related protein Rab-1B; RAB1B	Human	HEK293
	The RAB1B protein is an important small GTPase that regulates intracellular membrane trafficking by coordinating vesicular processes through cycling between GDP and GTP forms. It recruits downstream effectors to achieve vesicle functions, including formation, movement, and fusion. RAB1B Protein, Human (HEK293, Fc) is the recombinant human-derived RAB1B protein, expressed by HEK293 , with N-hFc labeled tag. The total length of RAB1B Protein, Human (HEK293, Fc) is 199 a.a., with molecular weight of ~58 kDa.

	RAB27B Protein, Human (HEK293) Ras-related protein Rab-27B; C25KG; RAB27B	Human	HEK293
	RAB27B is a dynamic small GTPase that regulates the late endocytic pathway by cycling between its active GTP-bound and inactive GDP-bound states. In the active state, RAB27B interacts with multiple effectors to coordinate endosomal localization, maturation, and secretion. RAB27B Protein, Human (HEK293) is the recombinant human-derived RAB27B protein, expressed by HEK293 , with tag free. The total length of RAB27B Protein, Human (HEK293) is 214 a.a., with molecular weight of ~27 kDa.

	RAB6A Protein, Human (His) Ras-related protein Rab-6A; Rab-6; RAB6A; RAB6	Human	E. coli
	RAB6A protein forms a complex with BICD1 and directly interacts with DYNLRB1 in the GDP-bound state, suggesting a regulatory role in coordinating cellular functions. In the GTP-bound state, RAB6A interacts with VPS13B, suggesting involvement in VPS13B-related pathways. RAB6A Protein, Human (His) is the recombinant human-derived RAB6A protein, expressed by E. coli , with N-His labeled tag. The total length of RAB6A Protein, Human (His) is 208 a.a., with molecular weight of ~26 kDa.

	RRAS2 Protein, Human RRas2; Ras-related protein R-Ras2; Ras-like protein TC21; Teratocarcinoma oncogene	Human	E. coli
	RRAS2 protein, a GTP-binding with GTPase activity, crucially regulates the MAPK signaling pathway, impacting diverse cellular processes and playing a pivotal role in orchestrating cellular responses. Its influence extends to regulating craniofacial development, emphasizing its multifaceted role in biological pathways essential for proper cellular and developmental outcomes. RRAS2 Protein, Human is the recombinant human-derived RRAS2 protein, expressed by E. coli , with tag free. The total length of RRAS2 Protein, Human is 204 a.a., .

	RAB27B Protein, Human (HEK293, His) Ras-related protein Rab-27B; C25KG; RAB27B	Human	HEK293
	RAB27B is a dynamic small GTPase that regulates the late endocytic pathway by cycling between its active GTP-bound and inactive GDP-bound states. In the active state, RAB27B interacts with multiple effectors to coordinate endosomal localization, maturation, and secretion. RAB27B Protein, Human (HEK293, His) is the recombinant human-derived RAB27B protein, expressed by HEK293 , with N-His labeled tag. The total length of RAB27B Protein, Human (HEK293, His) is 214 a.a., with molecular weight of ~29 kDa.

	RAB27B Protein, Human (HEK293, Fc) Ras-related protein Rab-27B; C25KG; RAB27B	Human	HEK293
	RAB27B is a dynamic small GTPase that regulates the late endocytic pathway by cycling between its active GTP-bound and inactive GDP-bound states. In the active state, RAB27B interacts with multiple effectors to coordinate endosomal localization, maturation, and secretion. RAB27B Protein, Human (HEK293, Fc) is the recombinant human-derived RAB27B protein, expressed by HEK293 , with N-mFc labeled tag. The total length of RAB27B Protein, Human (HEK293, Fc) is 214 a.a., with molecular weight of ~51 kDa.

	RRAS2 Protein, Human (His, Strep) RRas2; Ras-related protein R-Ras2; Ras-like protein TC21; Teratocarcinoma oncogene	Human	E. coli
	RRAS2 protein, a GTP-binding with GTPase activity, crucially regulates the MAPK signaling pathway, impacting diverse cellular processes and playing a pivotal role in orchestrating cellular responses. Its influence extends to regulating craniofacial development, emphasizing its multifaceted role in biological pathways essential for proper cellular and developmental outcomes. RRAS2 Protein, Human (His, Strep) is the recombinant human-derived RRAS2 protein, expressed by E. coli , with N-Strep, N-6*His labeled tag. The total length of RRAS2 Protein, Human (His, Strep) is 204 a.a., .

	RAC2 Protein, Human (His) Ras-related C3 botulinum toxin substrate 2; GX; Small G protein; p21-Rac2	Human	E. coli
	The RAC2 protein is a plasma membrane-associated small GTPase that dynamically regulates cellular responses by cycling between an active GTP-bound state and an inactive GDP-bound state. In its active state, RAC2 regulates secretory function, phagocytosis, and epithelial cell polarization. RAC2 Protein, Human (His) is the recombinant human-derived RAC2 protein, expressed by E. coli , with N-His labeled tag. The total length of RAC2 Protein, Human (His) is 189 a.a., with molecular weight of ~25 kDa.

	RAB11B Protein, Human (HEK293, His) Ras-related protein Rab-11B; GTP-binding protein YPT3; RAB11B; YPT3	Human	HEK293
	RAB11B protein is an important small GTPase in the Rab family, coordinating intracellular membrane transport by regulating vesicle processes. It cycles between GDP and GTP forms, recruiting effectors to control activities such as vesicle formation and movement. RAB11B Protein, Human (HEK293, His) is the recombinant human-derived RAB11B protein, expressed by HEK293 , with N-His labeled tag. The total length of RAB11B Protein, Human (HEK293, His) is 214 a.a., with molecular weight of ~25-30 kDa.

	RAC1 Protein, Human (sf9, GST) Ras-related C3 botulinum toxin substrate 1; p21-Rac1; RAC1; TC25; MIG5	Human	Sf9 insect cells
	The RAC1 protein is a plasma membrane-associated small GTPase that dynamically regulates multiple cellular responses by cycling between an active GTP-bound state and an inactive GDP-bound state. In its active form, RAC1 regulates processes such as secretory function, phagocytosis, cell polarization, neuronal activity, and growth factor-induced membrane ruffle formation. RAC1 Protein, Human (sf9, GST) is the recombinant human-derived RAC1 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of RAC1 Protein, Human (sf9, GST) is 189 a.a., with molecular weight of ~44 kDa.

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