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Results for "

Referance Inhibitors

" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-18744
    FLT3-IN-2

    FLT3 Cancer
    FLT3-IN-2 is a FLT3 inhibitor with IC50 of < 1 μM, detailed information refer to WO 2012158957 A2 and WO 2007013896.
  • HY-W008296
    NH2-C6-NH-Boc

    PROTAC Linker Cancer
    NH2-C6-NH-Boc is a PROTAC linker which refers to the alkyl/ether composition. NH2-C6-NH-Boc can be used in the synthesis the Mcl-1 inhibitor based on PROTAC.
  • HY-130422
    Tos-PEG4-t-butyl ester

    Tos-PEG4-Boc

    PROTAC Linker Cancer
    Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker, which refers to the PEG composition. Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) can be used in the synthesis of a series of PROTACs, such as BI-3663 (HY-111546). BI-3663 is a highly selective PTK2/FAK PROTAC, with cereblon ligands to hijack E3 ligases for PTK2 degradation, and inhibits PTK2 with an IC50 of 18 nM.