Rhinovirus

By Targets:	Enterovirus (6) Acyltransferase (1) Adrenergic Receptor (1) Antibiotic (1) Apoptosis (1) Bacterial (1) CMV (1) COX (1) DNA/RNA Synthesis (1) Glucocorticoid Receptor (1) HSV (1) Influenza Virus (2) Interleukin Related (2) Smo (1) Virus Protease (1)
By Research Areas:	Cancer (1) Endocrinology (2) Infection (8) Inflammation/Immunology (6)

Targets Recommended: Enterovirus

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-106296

WIN 54954	Enterovirus	Infection
WIN 54954 is an orally active and broad-spectrum antipicornavirus agent. WIN 54954 is effectiveness against human rhinovirus, echovirus 9 and enterovirus infections .

HY-112258

IMP-1088 3 Publications Verification	DNA/RNA Synthesis	Infection
IMP-1088 is a potent human N-myristoyltransferases NMT1 and NMT2 dual inhibitor with IC₅₀s of <1 nM for HsNMT1 and HsNMT2. IMP-1088 has a K_d of <210 pM for HsNMT1. IMP-1088 efficiently blocks rhinovirus replication by blocking rhinovirus virus-encoded protein (VP0) N-myristoylation. IMP-1088 protects host cells from the cytotoxic effects of viral infection .

HY-13784

Pirodavir 3 Publications Verification R77975	Enterovirus	Infection
Pirodavir is a potent, broad-spectrum picornavirus inhibitor, and is highly active against both group A and group B *rhinovirus* serotypes. Pirodavir is very potent in a virus yield reduction assay (IC₉₀=2.3 nM).

HY-N1067

Xanthohumol Maximum Cited Publications 8 Publications Verification	COX Acyltransferase Apoptosis HSV CMV Influenza Virus	Infection Cancer
Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against *bovine viral diarrhea virus* (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV)**.

HY-P5836

Citrullinated LL-37 1cit	Interleukin Related Bacterial Enterovirus	Inflammation/Immunology
Citrullinated LL-37 1cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 1cit does not alter the antiviral effect of LL-37 toward human rhinovirus. Citrullinated LL-37 1cit shows antibacterial activity toward S. aureus. Citrullinated LL-37 1cit causes a reduction in the levels of IL-8, CCL5, and IL-6 mRNA induced by RV1B .

HY-W011733

Tulobuterol hydrochloride 1 Publications Verification C-78	Adrenergic Receptor Influenza Virus Antibiotic	Infection Inflammation/Immunology Endocrinology
Tulobuterol hydrochloride (C-78) is a long-acting β₂-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol hydrochloride is also a sympathomimetic agent used as a transdermal patch, increases normal diaphragm muscle strength . Tulobuterol hydrochloride inhibit *rhinovirus* replication and modulate airway inflammation .

HY-106161

Rupintrivir 5 Publications Verification AG7088	Virus Protease Enterovirus	Infection Inflammation/Immunology
Rupintrivirvr (AG7088), an antiviral agent, is a potent, selective and irreversible inhibitor of *human rhinovirus* (HRV) 3C protease. Rupintrivirvr inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and MRC-5 cell protection assays, with a mean EC₅₀** of 0.023 μM. Rupintrivirvr shows immune-modulatory effect .

HY-P5837

Citrullinated LL-37 2cit	Interleukin Related Enterovirus	Inflammation/Immunology
Citrullinated LL-37 2cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 2cit reduces LL-37 activity against HRV at 10 μg/mL and reduces the antibacterial effect of LL-37. Citrullinated LL-37 2cit causes a reduction in the levels of IL-8, CCL5, and IL-6 mRNA induced by RV1B. Citrullinated LL-37 2cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion .

HY-P5843

Citrullinated LL-37 4cit	Enterovirus	Infection
Citrullinated LL-37 3cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 3cit lacks all antiviral activity at 10 μg/mL and retains some activity against HRV at 30 μg/mL. Citrullinated LL-37 3cit reduces the immunomodulatory activity of LL-37. Citrullinated LL-37 3cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion .

HY-B0603

Fluticasone	Smo Glucocorticoid Receptor	Infection Inflammation/Immunology Endocrinology
Fluticasone is an inhaled corticosteroid used for respiratory research. Fluticasone is a Smo agonist with an IC₅₀ value of 99 nM. Fluticasone activates Hedgehog signaling and promotes the proliferation of primary neuronal stem or precursor cells .

Cat. No.	Product Name	Target	Research Area

HY-P5836

Citrullinated LL-37 1cit	Interleukin Related Bacterial Enterovirus	Inflammation/Immunology
Citrullinated LL-37 1cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 1cit does not alter the antiviral effect of LL-37 toward human rhinovirus. Citrullinated LL-37 1cit shows antibacterial activity toward S. aureus. Citrullinated LL-37 1cit causes a reduction in the levels of IL-8, CCL5, and IL-6 mRNA induced by RV1B .

HY-P5837

Citrullinated LL-37 2cit	Interleukin Related Enterovirus	Inflammation/Immunology
Citrullinated LL-37 2cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 2cit reduces LL-37 activity against HRV at 10 μg/mL and reduces the antibacterial effect of LL-37. Citrullinated LL-37 2cit causes a reduction in the levels of IL-8, CCL5, and IL-6 mRNA induced by RV1B. Citrullinated LL-37 2cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion .

HY-P5838

Citrullinated LL-37 5cit	Peptides	Inflammation/Immunology
Citrullinated LL-37 5cit is a citrullinated LL-37 (HY-P1222) peptide. The antiviral and antibacterial effects of Citrullinated LL-37 5cit are significantly reduced compared to native LL-37. Citrullinated LL-37 5cit is unable to reduce LPS-mediated release of TNF-α due to a lack of LPS-binding capacity .

HY-P5843

Citrullinated LL-37 4cit	Enterovirus	Infection
Citrullinated LL-37 3cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 3cit lacks all antiviral activity at 10 μg/mL and retains some activity against HRV at 30 μg/mL. Citrullinated LL-37 3cit reduces the immunomodulatory activity of LL-37. Citrullinated LL-37 3cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1067

Xanthohumol 5+ Cited Publications	Infection Structural Classification Chalcones Flavonoids Classification of Application Fields Humulus lupulus L. Source classification Phenols Polyphenols Plants Moraceae Disease Research Fields	COX Acyltransferase Apoptosis HSV CMV Influenza Virus
Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against *bovine viral diarrhea virus* (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV)**.

Species:	Virus (2) Human (1) Rhesus Macaque (1)
Tag:	His (1) Tag Free (1) GST (1) Fc (1)
Source:	HEK293 (2) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P72622

	ICAM-1/CD54 Protein, Rhesus Macaque (HEK293, Fc) Intercellular Adhesion Molecule 1; ICAM-1; Major Group Rhinovirus Receptor; CD54; ICAM1	Rhesus Macaque	HEK293
	The ICAM-1/CD54 protein is a ligand of the leukocyte adhesion protein LFA-1 and is critical for leukocyte transendothelial migration. Its involvement activates ARHGEF26/SGEF and RHOG, coordinating endothelial apical cup assembly. ICAM-1/CD54 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived ICAM-1/CD54 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ICAM-1/CD54 Protein, Rhesus Macaque (HEK293, Fc) is 453 a.a., with molecular weight of 100-130 kDa.

HY-P72621

	ICAM-1/CD54 Protein, Human (453a.a, HEK293, His) Intercellular Adhesion Molecule 1; ICAM-1; Major Group Rhinovirus Receptor; CD54; ICAM1	Human	HEK293
	The ICAM-1/CD54 protein plays a crucial role in cell interactions, acting as a ligand for the leukocyte adhesion protein LFA-1. It promotes leukocyte transendothelial migration by promoting the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. ICAM-1/CD54 Protein, Human (453a.a, HEK293, His) is the recombinant human-derived ICAM-1/CD54 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of ICAM-1/CD54 Protein, Human (453a.a, HEK293, His) is 453 a.a., with molecular weight of ~88 kDa.

HY-P701920

	*3C protease Protein, Human rhinovirus* 14** Genome polyprotein	Virus	E. coli
	The 3C protease protein forms an icosahedral capsid with the VP2 and VP3 proteins, with a diameter of 300 angstroms. 3C protease Protein, Human rhinovirus 14 is the recombinant Virus-derived 3C protease protein, expressed by E. coli , with tag free. The total length of 3C protease Protein, Human rhinovirus 14 is 182 a.a., .

HY-P701921

	*3C protease Protein, Human rhinovirus* 14 (GST)** Genome polyprotein	Virus	E. coli
	The 3C protease protein forms an icosahedral capsid with the VP2 and VP3 proteins, with a diameter of 300 angstroms. 3C protease Protein, Human rhinovirus 14 (GST) is the recombinant Virus-derived 3C protease protein, expressed by E. coli , with N-GST labeled tag. The total length of 3C protease Protein, Human rhinovirus 14 (GST) is 182 a.a., .


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Cat. No.	Product Name	Application	Reactivity

HY-P80716

ICAM1 Antibody (YA352) ICAM1; Intercellular adhesion molecule 1; ICAM-1; Major group Rhinovirus receptor; CD antigen CD54	WB, IHC-P, IP	Human
ICAM1 Antibody (YA352) is a non-conjugated and Rabbit origined monoclonal antibody about 58 kDa, targeting to ICAM1. It can be used for WB,IHC-P,IP assays with tag free, in the background of Human.

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Rhinovirus

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