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Scavenger

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85

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14

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Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W011370

    Reactive Oxygen Species Others
    Pelargonidin chloride is a scavenger of nitric oxide radical and has antioxidant activities .
    Pelargonidin chloride
  • HY-131898

    Others Others
    PTIO is a specific scavenger of NO. PTIO reacts with •NO to form the corresponding imino nitroxides and NO2 .
    PTIO
  • HY-W016286

    2,6-Dimercaptopurine

    Others Cancer
    2,6-Dithiopurine (2,6-Dimercaptopurine) is a nucleophilic scavenger for electrophilic carcinogens. 2,6-Dithiopurine abolishes both DNA adduct formation and the initiation of carcinogenesis .
    2,6-Dithiopurine
  • HY-155346

    Others Others
    Free radical scavenger 1 (compound 8) shows scavenging activity against the DPPH radical, with the IC50 of 43.39 μg/ml .
    Free radical <em>scavenger</em> 1
  • HY-122921

    Reactive Oxygen Species Cancer
    5-Galloylquinic acid, an main scavenger of the reactive oxygen species (ROS) in green tea .
    5-Galloylquinic acid
  • HY-N8042

    Others Others
    Erigeside I is a free radical scavenger isolated from Erigeron breviscapus .
    Erigeside I
  • HY-W015913
    Sodium 2-oxopropanoate
    5 Publications Verification

    Sodium pyruvate

    Reactive Oxygen Species Endogenous Metabolite Metabolic Disease
    Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .
    Sodium 2-oxopropanoate
  • HY-N8844

    Others Others
    2"-O-Galloylquercitrin (Compound 6) is isolated from the natural Acer ginnala. 2"-O-Galloylquercitrin has health benefits. 2"-O-Galloylquercitrin has the activity of free radical scavenger .
    2''-O-Galloylquercitrin
  • HY-N3847

    Eriodictyol 7-O-β-D-glucoside

    Keap1-Nrf2 Metabolic Disease
    Eriodictyol-7-O-glucoside (Eriodictyol 7-O-β-D-glucoside), a flavonoid, is a potent free radical scavenger. Eriodictyol-7-O-glucoside is also an Nrf2 activator, confers protection against Cisplatin-induced toxicity .
    Eriodictyol-7-O-glucoside
  • HY-106408A

    Salfaprodil; Neu2000 potassium

    iGluR Neurological Disease
    Nelonemdaz (Salfaprodil) potassium is an NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). Nelonemdaz potassium is also a free radical scavenger. Nelonemdaz potassium has excellent neuroprotection against NMDA- and free radical-induced cell death .
    Nelonemdaz potassium
  • HY-106408

    Salfaprodil free base; Neu2000

    iGluR Neurological Disease
    Nelonemdaz (Salfaprodil free base) is an NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). Nelonemdaz is also a free radical scavenger. Nelonemdaz has excellent neuroprotection against NMDA- and free radical-induced cell death .
    Nelonemdaz
  • HY-129460
    XJB-5-131
    2 Publications Verification

    Reactive Oxygen Species Neurological Disease
    XJB-5-131 is a mitochondria-targeted ROS and electron scavenger . XJB-5-131 is a bi-functional antioxidant that comprises a radical scavenger. XJB-5-131 is a synthetic antioxidant that targets mitochondria . XJB-5-131 is an effective ionizing irradiation protector and mitigator of cord blood mononuclear cells (CB MNCs) .
    XJB-5-131
  • HY-147240

    ADX-629

    Others Infection Cardiovascular Disease Inflammation/Immunology
    Acloproxalap is a quinoline-based aldehyde scavenger that can be used in studies of diseases with toxic aldehyde accumulation, such as inflammatory diseases of the eye and skin, respiratory diseases such as pneumonia, organ diseases, and viral infection-related syndromes .
    Acloproxalap
  • HY-125568

    Others Others
    Pyridoxatin is a free radical scavenger of microbial origin. Pyridoxatin is isolated from a fungus culture identified as Acremonium sp. BX86. Pyridoxatin inhibits lipid peroxidation induced by free radicals in rat liver microsomes free from vitamin E .
    Pyridoxatin
  • HY-101499
    GKT136901
    1 Publications Verification

    NADPH Oxidase Neurological Disease Metabolic Disease Inflammation/Immunology
    GKT136901 is a potent, selective and orally active inhibitor of NADPH oxidase (NOX1/4), with Kis of 160 and 165 nM, respectively. GKT136901 is also a selective and direct scavenger of peroxynitrite. GKT136901 can be used for the research of diabetic nephropathy, stroke, and neurodegeneration. GKT136901 also has anti-inflammatory activity .
    GKT136901
  • HY-101499A
    GKT136901 hydrochloride
    1 Publications Verification

    NADPH Oxidase Neurological Disease Metabolic Disease
    GKT136901 hydrochloride is a potent, selective and orally active inhibitor of NADPH oxidase (NOX1/4), with Kis of 160 and 165 nM, respectively. GKT136901 hydrochloride is also a selective and direct scavenger of peroxynitrite. GKT136901 hydrochloride can be used for the research of diabetic nephropathy, stroke, and neurodegeneration. GKT136901 hydrochloride also has anti-inflammatory activity .
    GKT136901 hydrochloride
  • HY-W032848

    Y-3642

    COX Inflammation/Immunology
    Tinoridine (Y-3642) is an orally active non-steroidal anti-inflammatory agent with potent antiperoxidative ability and radical scavenger activity. Tinoridine acts function by inhibiting COX enzyme, involves in hepatotoxicity inhibition. .
    Tinoridine
  • HY-N1430

    trans-Oxyresveratrol

    Tyrosinase HSV Autophagy Others
    Oxyresveratrol (trans-Oxyresveratrol) is a potent naturally occurring antioxidant and free radical scavenger (IC50 of 28.9 µM against DPPH free radicals). Oxyresveratrol is potent and noncompetitive tyrosinase inhibitor with an IC50 value of 1.2 µM for mushroom tyrosinase. Oxyresveratrol is effective against HSV-1, HSV-2 and varicella-zoster virus, and has neuroprotective effects .
    Oxyresveratrol
  • HY-126397
    MnTBAP chloride
    1 Publications Verification

    NF-κB Inflammation/Immunology
    MnTBAP chloride is a superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. MnTBAP chloride is a manganic porphyrin complex and has anti-oxidative property. MnTBAP chloride mediates anti-inflammatory effects through upregulation of BMPR-II and inhibition of the NFκB signaling. MnTBAP chloride has the potential for the fibrotic response in chronic kidney diseases (CKDs) research .
    MnTBAP chloride
  • HY-154857

    Others Cancer
    1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine is a glycerophosphorylcholine, consisting of glycerol phosphate, choline and palmitic acid. It accumulates in vivo at sites of oxidative stress. 1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine may be a ligand of scavenger receptors class B, while oxidized phospholipids oxPC(CD36) are potent ligands of scavenger receptors class B (CD36 and SR-BI). Oxidized phospholipids (oxPLs) also play an important role in tumor apoptosis, may be elevated in malignant biliary strictures .
    1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine
  • HY-116767
    BLT-1
    3 Publications Verification

    Block lipid transport-1

    HCV Metabolic Disease Inflammation/Immunology
    BLT-1, a thiosemicarbazone copper chelator, is a selective scavenger receptor B, type 1 (SR-BI) inhibitor. BLT-1 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. BLT-1 is a potent HCV entry inhibitor .
    BLT-1
  • HY-128463

    COX Reactive Oxygen Species Neurological Disease Metabolic Disease Inflammation/Immunology
    N-tert-Butyl-α-phenylnitrone is a nitrone-based free radical scavenger that forms nitroxide spin adducts. N-tert-Butyl-α-phenylnitrone inhibits COX2 catalytic activity. N-tert-Butyl-α-phenylnitrone has potent ROS scavenging, anti-inflammatory, neuroprotective, anti-aging and anti-diabetic activities, and can penetrate the blood-brain barrier .
    N-tert-Butyl-α-phenylnitrone
  • HY-100592
    Nicaraven
    1 Publications Verification

    Others Cancer
    Nicaraven is a novel chemically synthesized hydroxyl radical-specific scavenger.
    Nicaraven
  • HY-N10065

    Others Others
    Samwirin A is a promising radical scavenger in aqueous media at physiological pH.
    Samwirin A
  • HY-N0525
    Ethyl gallate
    1 Publications Verification

    Bacterial Metabolic Disease Cancer
    Ethyl gallate is a nonflavonoid phenolic compound and also a scavenger of hydrogen peroxide.
    Ethyl gallate
  • HY-111354

    Y-3642 hydrochloride

    Glutathione Peroxidase Inflammation/Immunology
    Tinoridine hydrochloride is a nonsteroidal anti-inflammatory agent and also has potent radical scavenger and antiperoxidative activity.
    Tinoridine hydrochloride
  • HY-138454

    Mercaptoethylguanidine hemisulfate

    NO Synthase Inflammation/Immunology
    MEG (Mercaptoethylguanidine) hemisulfate is a potent and selective inhibitor of the inducible NO synthase (iNOS), with EC50s of 11.5, 110, and 60 μM for iNOS, ecNOS, and bNOS respectively in tissue homogenates. MEG hemisulfate is also a potent scavenger of peroxynitrite and inhibits peroxynitrite-induced oxidative processes. MEG hemisulfate has a protective effect in many experimental models of inflammation, including ischemia/reperfusion injury, periodontitis, hemorrhagic shock, inflammatory bowel disease, and endotoxic and septic shock .
    MEG hemisulfate
  • HY-131036

    Monoamine Oxidase Neurological Disease
    MAO-IN-M30 dihydrochloride is an orally active, brain-permeable, and brain selective irreversible MAO-A (IC50=37 nM) and MAO-B (IC50=57 nM) inhibitor. MAO-IN-M30 dihydrochloride is a potent iron chelator and radical scavenger. MAO-IN-M30 dihydrochloride has a neuroprotective effect against Dexamethasone-induced brain cell apoptosis. MAO-IN-M30 dihydrochloride also exhibits neurorestorative activity in post MPTP and lactacystin models of Parkinson's disease . MAO-IN-M30 (dihydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    MAO-IN-M30 dihydrochloride
  • HY-N9370

    Fungal Infection
    Isobellidifolin, a xanthone, is a free radical scavenger and antioxidant compound. Isobellidifolin has potent antifungal effect .
    Isobellidifolin
  • HY-U00005

    Reactive Oxygen Species Inflammation/Immunology
    AD 0261 is a radical scavenger which displays strong inhibitory action on the generation of lipid peroxides and superoxide anions.
    AD 0261
  • HY-N2183

    Quercetin 3-O-sophoroside

    Baimaside (Quercetin 3-O-sophoroside) is isolated from the flowers of A. venetum, is a scavenger of superoxide anions .
    Baimaside
  • HY-100297

    Prostaglandin Receptor Inflammation/Immunology Endocrinology
    MK-447 is a free radical scavenger, also a nonsteroidal antiinflammatory agent, and enhances the formation of the endoperoxide, PGH2, and other prostaglandins.
    MK-447
  • HY-19900
    ITX5061
    2 Publications Verification

    p38 MAPK Autophagy HCV Infection
    ITX5061 is a type II inhibitor of p38 MAPK and also an antagonist of scavenger receptor B1 (SR-B1).
    ITX5061
  • HY-B0099
    Edaravone
    Maximum Cited Publications
    16 Publications Verification

    MCI-186

    MMP Apoptosis Neurological Disease
    Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator.
    Edaravone
  • HY-115744

    NO Synthase Inflammation/Immunology
    Mercaptoethylguanidine (MEG) dihydrobromide is selective inhibitor of the inducible nitric oxide synthase and peroxynitrite scavenger. Mercaptoethylguanidine (MEG) dihydrobromide has the potential for inflammatory bowel diseases research.
    Mercaptoethylguanidine (MEG) (dihydrobromide)
  • HY-114651

    Others Cancer
    Phenazoviridin is a free radical scavenger. Phenazoviridin shows strong inhibitory activity against lipid peroxidation in rat brain homogenate and exhibits antihypoxic activity in mice .
    Phenazoviridin
  • HY-N10594

    Drug Metabolite Metabolic Disease
    Cirsiliol 4′-glucoside is a free radical scavenger, found from Ruellia tuberosa L. Cirsiliol 4′-glucoside shows potential anti-diabetic activity .
    Cirsiliol 4′-glucoside
  • HY-130750

    Reactive Oxygen Species Neurological Disease
    Phycocyanobilin, an orally active antioxidative agent, is an effective scavenger for various reactive oxygen species. Phycocyanobilin can be used for the research of Alzheimer’s disease .
    Phycocyanobilin
  • HY-B2087

    HPN-100

    Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand, with a pKi of 8.02. Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger agent .
    Glycerol phenylbutyrate
  • HY-135849
    Catalase, Aspergillus niger
    1 Publications Verification

    Reactive Oxygen Species Cancer
    Catalase, Aspergillus niger is a key enzyme in the metabolism of H2O2 and reactive oxygen species (ROS), and its expression and localization is markedly altered in tumors . Free oxygen radical scavenger.
    Catalase, Aspergillus niger
  • HY-N0683
    α-Vitamin E
    10+ Cited Publications

    (+)-α-Tocopherol; D-α-Tocopherol

    Bacterial Influenza Virus Reactive Oxygen Species Ferroptosis Endogenous Metabolite Infection Cancer
    α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant .
    α-Vitamin E
  • HY-13244

    NXY-059

    Reactive Oxygen Species Neurological Disease
    Disufenton sodium (NXY-059) is the disulfonyl derivative of the neuroprotective spin trap phenylbutynitrone(PBN), both NXY-059, its parent PBN and their hydrolysis/oxidation product MNT are very powerful scavengers of free radicals.
    Disufenton sodium
  • HY-N1353

    Rhamnocitrin is a flavonoid isolated from astragalus complanatus R. Br. (Sha-yuan-zi) . Rhamnocitrin is a scavenger of DPPH with an IC50 of 28.38 mM. Rhamnocitrin has anti-oxidant, anti-inflammatory and an-tiatherosclerosis activity .
    Rhamnocitrin
  • HY-B2130
    Uric acid
    5+ Cited Publications

    Reactive Oxygen Species Endogenous Metabolite Inflammation/Immunology
    Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation .
    Uric acid
  • HY-N12267

    Melanocortin Receptor Metabolic Disease
    N,N′-Diferuloylputrescine is a inhibitor of pigmentation with 57% reduction. N,N′-Diferuloylputrescine significantly reduces the protein level of MITF. N,N′-Diferuloylputrescine has strong antioxidant activities as radical scavengers against reactive oxygen species .
    N,N′-Diferuloylputrescine
  • HY-B0099S

    MCI-186-d5

    MMP Apoptosis Neurological Disease
    Edaravone-d5 is a deuterium labeled Edaravone. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator[1][2][3][4].
    Edaravone-d5
  • HY-B2130A
    Uric acid sodium
    5+ Cited Publications

    Monosodium urate

    Reactive Oxygen Species Endogenous Metabolite Metabolic Disease
    Uric acid sodium (Monosodium urate), scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid sodium can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation .
    Uric acid sodium
  • HY-120380

    Autophagy Inflammation/Immunology
    FeTMPyP is an orally active peroxynitrite (ONOO ?) scavenger. FeTMPyP reduces nitrative stress and increases autophagy. FeTMPyP reduces PARP over-activation and neuroinflammation in chronic constriction injury (CCI)-induced rats, and ameliorates functional, behavioral and biochemical deficits .
    FeTMPyP
  • HY-N0523
    Gallic acid
    5+ Cited Publications

    3,4,5-Trihydroxybenzoic acid

    COX Reactive Oxygen Species Apoptosis Ferroptosis Endogenous Metabolite Metabolic Disease Cancer
    Gallic acid (3,4,5-Trihydroxybenzoic acid) is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2) . Gallic acid has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities .
    Gallic acid
  • HY-18734A
    Carboxy-PTIO potassium
    3 Publications Verification

    NO Synthase Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    Carboxy-PTIO potassium is a potent nitric oxide (NO) scavenger that can make a quick reaction with NO to produce NO2. Carboxy-PTIO potassium can prevent hypotension and endotoxic shock through the direct scavenging action against NO in lipopolysaccharide-stimulated rat model .
    Carboxy-PTIO potassium

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