Search Result

Results for "

Sigma

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Sigma Receptor (77) 5-HT Receptor (8) Adrenergic Receptor (2) Akt (2) Apoptosis (4) Bacterial (1) Casein Kinase (1) Cholinesterase (ChE) (1) Cytochrome P450 (1) DNA/RNA Synthesis (2) Dopamine Receptor (6) Estrogen Receptor/ERR (1) Ferroptosis (1) Fluorescent Dye (1) Histamine Receptor (6) iGluR (1) mAChR (4) Monoamine Oxidase (1) NO Synthase (2) Opioid Receptor (6) Phosphatase (3) PI3K (1) Potassium Channel (2) PPAR (1) SARS-CoV (3) SHP2 (1)
By Research Areas:	Cancer (16) Cardiovascular Disease (3) Endocrinology (1) Infection (4) Inflammation/Immunology (13) Metabolic Disease (2) Neurological Disease (71)

By Targets:

Sigma Receptor (77)

5-HT Receptor (8)

Adrenergic Receptor (2)

Akt (2)

Apoptosis (4)

Bacterial (1)

Casein Kinase (1)

Cholinesterase (ChE) (1)

Cytochrome P450 (1)

DNA/RNA Synthesis (2)

Dopamine Receptor (6)

Estrogen Receptor/ERR (1)

Ferroptosis (1)

Fluorescent Dye (1)

Histamine Receptor (6)

iGluR (1)

mAChR (4)

Monoamine Oxidase (1)

NO Synthase (2)

Opioid Receptor (6)

Phosphatase (3)

PI3K (1)

Potassium Channel (2)

PPAR (1)

SARS-CoV (3)

SHP2 (1)

By Research Areas:

Cancer (16)

Cardiovascular Disease (3)

Endocrinology (1)

Infection (4)

Inflammation/Immunology (13)

Metabolic Disease (2)

Neurological Disease (71)

104

Inhibitors & Agonists

Fluorescent Dye

Peptides

Natural
Products

Recombinant Proteins

Antibodies

Targets Recommended: Sigma Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101626

Sigma-LIGAND-1	Sigma Receptor	Neurological Disease
Sigma-LIGAND-1 is a selective sigma receptor ligand with an IC₅₀s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 has a K_i of 4000 nM at the dopamine D₂ receptor .

HY-101626A

Sigma-LIGAND-1 hydrochloride	Sigma Receptor	Neurological Disease
Sigma-LIGAND-1 hydrochloride is a selective sigma receptor ligand with an IC₅₀s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 hydrochloride has a K_i of 4000 nM at the dopamine D₂ receptor .

HY-125819

Sigma-1 receptor antagonist 2	Sigma Receptor	Neurological Disease
Sigma-1 receptor antagonist 2 is a potent and selective sigma 1 receptor (σ1 R) antagonist with K_is of 3.88 and 1288 nM for σ1 and σ2 receptor, respectively .

HY-125820

Sigma-1 receptor antagonist 3	Sigma Receptor Potassium Channel	Neurological Disease
Sigma-1 receptor antagonist 3 (compound135) is a potent and selective Sigma-1 (σ1) receptor antagonist with a K_i of 1.14 nM. Sigma-1 receptor antagonist 3 inhibits Human Ether-a-go-go-Related Gene (hERG) with an IC₅₀ of 1.54 μM. Sigma-1 receptor antagonist 3 has the potential for the neuropathic pain .

HY-156124

Sigma-2 Radioligand 1	Sigma Receptor	Cancer
Sigma-2 Radioligand 1 (compound 1) is a Sigma-2 selective ligand. Sigma-2 Radioligand 1 has good biodistribution in mice and good in vivo activity in rats. [18F] Modified Sigma-2 Radioligand 1 for visualization of tumors in micro-PET/CT imaging, exhibiting high tumor uptake and tumor-to-background ratio. Experiments show that Sigma-2 Radioligand 1 binds highly specifically in U87MG glioma xenografts .

HY-125821

Sigma-1 receptor antagonist 1	Sigma Receptor	Neurological Disease
Sigma‑1 receptor antagonist 1 (compound 137) is a potent and selective **sigma-1 receptor (σ1R) antagonist, with a high binding affinity to σ1R receptor (K_i** = 1.06 nM). Sigma‑1 receptor antagonist 1 exhibits antineuropathic pain activity and acts as a promising agent for the treatment of neuropathic pain .

HY-149335

Sigma-1 receptor antagonist 5	Sigma Receptor Histamine Receptor	Neurological Disease
Sigma-1 receptor antagonist 5 (compound 12)，a 4-pyridylpiperidine derivative with analgesic activity，is an antagonist of sigma receptor (Ki=4.5 nM (σ1R)，10 nM (σ2R)) and histamine H3 (hH₃R，Ki=7.7 nM，IC₅₀=215 nM). Sigma-1 receptor antagonist 5 suppresses Capsaicin-induced nociception with antinociceptive activity and shows potent efficacy in nociceptive and neuropathic pain models .

HY-149274

Sigma-1 receptor antagonist 4	Sigma Receptor	Neurological Disease
Sigma-1 receptor antagonist 4 (Compound 32) is a potent *σ1R* antagonist that significantly enhances the analgesic effect of morphine and rescues morphine-induced analgesic tolerance, with potential to prevent morphine tolerance .

HY-111669

CT1812 1 Publications Verification Sigma-2 receptor antagonist 1	Sigma Receptor	Neurological Disease
CT1812 (Sigma-2 receptor antagonist 1) is an orally active and brain penetrant *sigma-2* receptor antagonist with a K_i of 8.5 nM. CT1812 can be used for the research of Alzheimer’s disease .

HY-156125

14-3-3σ/ERα stabilizer-1	Estrogen Receptor/ERR	Others
14-3-3σ/ERα stabilizer-1 (Compound 181) is a covalent *14-3-3σ*/ERα stabilizer. 14-3-3σ/ERα stabilizer-1 can be used for research of molecular glues .

HY-10815

σ1 Receptor antagonist-1 1 Publications Verification	Sigma Receptor Apoptosis	Neurological Disease Cancer
σ1 Receptor antagonist-1 is a highly potent and selective sigma 1 receptor antagonist (pK_i=10.28). σ1 Receptor antagonist-1 inhibits cell growth, arrests cell cycle at G0/G1 phase and induces apoptosis of MCF-7/ADR cells .

HY-147560

σ1 Receptor/μ Opioid receptor modulator 1	Sigma Receptor Opioid Receptor	Neurological Disease
σ1 Receptor/μ Opioid receptor modulator 1 (Compound 44) is a potent σ1 receptor antagonist and μ opioid receptor agonist with K_is of 1.86 nM and 2.1 nM, respectively.σ1 Receptor/μ Opioid receptor modulator 1 exhibits potent analgesic activity. σ1 Receptor/μ Opioid receptor modulator 1 can be used for the research of neuropathic pain .

HY-163065

σ1 Receptor/μ Opioid receptor modulator 2	Opioid Receptor Sigma Receptor	Neurological Disease
σ1 Receptor/μ Opioid receptor modulator 2 (compound 4x) is a dual μOR agonist/σ1R antagonist, and displays picomolar μOR agonism activity (EC₅₀: 0.6 ± 0.2 nM) and good *σ1R* inhibitory activity (K_i: 363.7 ± 5.6 nM). σ1 Receptor/μ Opioid receptor modulator 2 exhibits robust analgesic effects in various pain models .

HY-136281

DuP 734	Sigma Receptor	Neurological Disease
DuP 734 is a sigma receptor antagonist. DuP 734 is a selective and potent sigma and 5-HT2 receptor ligand with weak affinity for D2 receptors. DuP 734 may have antipsychotic activity without the liability of motor side effects typical of neuroleptics .

HY-19120

KB-5492 anhydrous	Sigma Receptor	Inflammation/Immunology
KB-5492 anhydrous is a potent and selective inhibitor of sigma receptor, inhibits specific [ ³H]1,3-di(2-tolyl)guanidine (DTG) binding to the sigma receptor with an IC₅₀ of 3.15 μM. KB-5492 anhydrous is an anti-ulcer agent .

HY-47228

KB-5492 free base	Sigma Receptor	Inflammation/Immunology
KB-5492 free base is a potent and selective inhibitor of sigma receptor, inhibits specific [ ³H]1,3-di(2-tolyl)guanidine (DTG) binding to the sigma receptor with an IC₅₀ of 3.15 μM. KB-5492 free base is an anti-ulcer agent .

HY-120842

RLH-033	mAChR	Neurological Disease
RLH-033 is a potent and selective ligand for the sigma 1 recognition site. RLH-033 has high affinity for sigma 1 sites labeled by [ ³H](+)-pentazocine with a K_i of 50 pM .

HY-118901

Opipramol Ensidon; G-33040	Sigma Receptor	Neurological Disease
Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA). Opipramol acts primarily as a sigma (σ) receptor agonist and can potently interact with sigma recognition sites with a K_i value of 50 nM. Opipramol can be used for the research of generalized anxiety disorder (GAD) .

HY-121813

Rimcazole BW 234U	Others	Neurological Disease
Rimcazole (BW 234U) is a potent antipsychotic agent. Rimcazole also is a competitive antagonist of sigma sites. Rimcazole can be used for the research of acute schizophrenic diseases .

HY-B1216

Oxeladin citrate	Sigma Receptor	Cardiovascular Disease Others Neurological Disease
Oxeladin citrate is an orally active and brain-penetrant cough suppressant as well as a selective sigma 1 receptor agonist (K_i = 25 nM). Oxeladin can be used for pulmonary diseases and stroke research .

HY-108509

BMY-14802 hydrochloride BMY-14802-1; BMS 181100 hydrochloride	Sigma Receptor 5-HT Receptor Adrenergic Receptor	Neurological Disease
BMY-14802 hydrochloride (BMY-14802-1) is a selective and orally active sigma receptor antagonist with an IC₅₀ of 112 nM. BMY-14802 hydrochloride is also a 5-HT1A and adrenergic α1 receptors agonist. BMY-14802 hydrochloride has antipsychotic effects .

HY-14218

Ditolylguanidine 2 Publications Verification 1,3-Di-o-tolylguanidine; DTG	Sigma Receptor	Neurological Disease
Ditolylguanidine (1,3-Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor) with K_i values of 69 and 21 nM for σ1 and σ2 receptors, respectively. Ditolylguanidine effectively inhibits the growth of small cell lung cancer cells. Ditolylguanidine can be used for the research of lung cancer .

HY-14221

Siramesine Lu 28-179	Sigma Receptor	Cancer
Siramesine (Lu 28-179) is a potent sigma-2 receptor agonist. Siramesine has a subnanomolar affinity for sigma-2 receptors (IC₅₀=0.12 nM) and exhibits a 140-fold selectivity for sigma-2 receptors over sigma-1 receptors (IC₅₀=17 nM). Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes. Anti-cancer activity .

HY-14221A

Siramesine hydrochloride 4 Publications Verification Lu 28-179 hydrochloride	Sigma Receptor Ferroptosis	Cancer
Siramesine (Lu 28-179) hydrochloride is a potent sigma-2 receptor agonist. Siramesine hydrochloride has a subnanomolar affinity for sigma-2 receptors (IC₅₀=0.12 nM) and exhibits a 140-fold selectivity for sigma-2 receptors over sigma-1 receptors (IC₅₀=17 nM). Siramesine hydrochloride triggers cell death through destabilisation of mitochondria, but not lysosomes. Anti-cancer activity .

HY-14221B

Siramesine fumarate LU-28-179 fumarate	Sigma Receptor	Cancer
Siramesine (Lu 28-179) fumarate is a potent sigma-2 receptor agonist. Siramesine fumarate has a subnanomolar affinity for sigma-2 receptors (IC₅₀=0.12?nM) and exhibits a 140-fold selectivity for sigma-2 receptors over sigma-1 receptors (IC₅₀=17?nM). Siramesine fumarate triggers cell death through destabilisation of mitochondria, but not lysosomes. Anti-cancer activity .

HY-155615

KSK67	Sigma Receptor Histamine Receptor	Neurological Disease
KSK67 is a high-affinity dual *sigma-2* and histamine H3 receptor antagonist, with K_is of 3.2, 1531, 101 nM for H3 receptor, sigma-1, sigma-2 receptor respectively. KSK67 can be used for research of nociceptive and neuropathic pain .

HY-155614

KSK68	Sigma Receptor Histamine Receptor	Neurological Disease
KSK68 is a high-affinity dual *sigma-1* and histamine H3 receptor antagonist, with K_is of 7.7, 3.6, 22.4 nM for H3 receptor, sigma-1, sigma-2 receptor respectively. KSK68 has negligible affinity at the other histamine receptor subtypes. KSK68 can be used for research of nociceptive and neuropathic pain .

HY-14813

Cutamesine SA4503; AGY 94806	Sigma Receptor	Neurological Disease
Cutamesine (SA4503; AGY-94806) is a selective sigma 1 receptor(σ1R) agonist; high affinity for the sigma 1 receptor (IC50= 17.4±1.9 nM); 100-fold less affinity for the sigma 2 receptor.

HY-145628

CM398	Sigma Receptor	Neurological Disease Inflammation/Immunology
CM398 is a highly selective, orally active sigma-2 receptor ligand (K_i=0.43 nM), with high sigma-1/sigma-2 selectivity rato (1000-fold). CM398 shows notable affinity for dopamine (K_i=32.90 nM) and serotonin transporters (K_i=244.2 nM). CM398 shows promising anti-inflammatory analgesic effects in the formalin model of inflammatory pain in mice .

HY-111081C

(±)-PPCC oxalate	Sigma Receptor	Neurological Disease
(±)-PPCC oxalate is a *sigma-1* agonist that mainly interacts with *sigma-1* receptors with K_i of 1.5 nM. (±)-PPCC oxalate has effective anti-amnesia effects in rats with mild or severe cognitive impairment, and can improve the cognitive abilities of rats .

HY-B2087

Glycerol phenylbutyrate HPN-100
Glycerol phenylbutyrate is a **sigma-2 (σ2) receptor ligand, with a pK_i** of 8.02. Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger agent .

HY-155616

KSK94	Sigma Receptor Histamine Receptor	Neurological Disease
KSK94 is a high-affinity histamine H3 receptor antagonist, with K_is of 7.9, 2958, 75.2 nM for H3 receptor, sigma-1, sigma-2 receptor respectively. KSK94 can be used for research of nociceptive and neuropathic pain .

HY-100155

4-IBP	Sigma Receptor	Cancer
4-IBP is a selective σ1 agonist, binding to σ1 receptors with high affinity (Ki = 1.7 nM) and with slightly weaker affinity to σ2 receptors (Ki = 25.2 nM).

HY-101864

Blarcamesine hydrochloride 2 Publications Verification Anavex 2-73	Sigma Receptor	Neurological Disease Cancer
Blarcamesine hydrochloride (Anavex 2-73) is a Sigma-1 Receptor agonist with an IC₅₀ of 860 nM.

HY-19469

Roluperidone 1 Publications Verification CYR-101; MIN-101; MT-210	5-HT Receptor Sigma Receptor	Neurological Disease
Roluperidone (CYR-101) is a novel cyclic amide derivative that has high equipotent affinities for 5-HT_2A and *sigma-2* receptors (K_i of 7.53 nM and 8.19 nM for 5-HT_2A and sigma-2, respectively).

HY-108512

PD 144418	Sigma Receptor	Neurological Disease
PD 144418 is a highly affinity, potent and selective sigma 1 (σ1) receptor ligand (K_i values of 0.08 nM and 1377 nM for σ1 and σ2 respectively). PD 144418 devoids of any significant affinity for other receptors, ion channels and enzymes. PD 144418 shows potential antipsychotic activity .

HY-134004

Pentoxyverine Carbetapentane	Sigma Receptor mAChR	Neurological Disease Inflammation/Immunology
Pentoxyverine (Carbetapentane) is an orally active sigma-1 receptor agonist, with K_is of 41 nM, 894 nM and 75 nM for σ1, σ2 and guinea-pig brain membran σ1, respectively. Pentoxyverine is a muscarinic antagonist. Pentoxyverine is a potent antitussive, anticonvulsant, and spasmolytic agent. Pentoxyverine can be used for inhibiting bronchial interceptor, weakening of cough reflex, bronchial smooth muscle relaxation and reduction of airway resistance .

HY-100985

IPAG

IPAG is a potent sigma-1 receptor antagonist with a pK_i of 4.3 . IPAG induces apoptosis .

IPAG
IPAG is a potent sigma-1 receptor antagonist with a pK_i of 4.3 . IPAG induces apoptosis .

HY-B1055

Pentoxyverine citrate Carbetapentane citrate	Sigma Receptor mAChR	Neurological Disease Inflammation/Immunology
Pentoxyverine (Carbetapentane) citrate is an orally active sigma-1 receptor agonist, with K_is of 41 nM, 894 nM and 75 nM for σ1, σ2 and guinea-pig brain membrane σ1, respectively. Pentoxyverine citrate is a muscarinic antagonist. Pentoxyverine citrate is a potent antitussive, anticonvulsant, and spasmolytic agent. Pentoxyverine citrate can be used for inhibiting bronchial interceptor, weakening of cough reflex, bronchial smooth muscle relaxation and reduction of airway resistance .

HY-108512A

PD 144418 oxalate	Sigma Receptor	Neurological Disease
PD 144418 oxalate is a highly affinity, potent and selective sigma 1 (σ1) receptor ligand (K_i values of 0.08 nM and 1377 nM for σ1 and σ2 respectively). PD 144418 oxalate devoids of any significant affinity for other receptors, ion channels and enzymes. PD 144418 oxalate shows potential antipsychotic activity .

HY-155484

SOMCL-668	Sigma Receptor	Neurological Disease
SOMCL-668 is a selective and potent sigma-1 receptor allosteric modulator. ?SOMCL-668 shows positive modulation of improvement in social deficits and cognitive impairment induced by the selective sigma-1 agonist PRE084.?SOMCL-668 displays anti-seizure activities and can be used for psychotic illness research .

HY-P5982

PTPσ Inhibitor, ISP	Phosphatase	Neurological Disease
PTPσ Inhibitor, ISP can bind to recombinant human PTPs and inhibits PTPσ signaling. PTPσ Inhibitor, ISP can penetrate the membrane and relieves the chondroitin sulfate proteoglycan (CSPG)-mediated axonal sprouting inhibition in spinal cord injury model. PTPσ Inhibitor, ISP enhances remyelination in LPC-induced demyelinated spinal cord. PTPσ Inhibitor, ISP also promotes oligodendrocyte progenitor cells (OPCs) migration, maturation, remyelination, and functional recovery in animal models of Multiple Sclerosis (MS) .

HY-163075

SYB4

Others Others

SYB4 (compound 5) is a PET tracer which suitable for imaging the Sigma-2 Receptor in the brain of nonhuman primates .
HY-116463

E1R

Sigma Receptor Neurological Disease

E1R is a positive allosteric modulator of sigma-1 receptors (Sig1R PAM) with cognition-enhancing activity .

SYB4	Others	Others
SYB4 (compound 5) is a PET tracer which suitable for imaging the Sigma-2 Receptor in the brain of nonhuman primates .

E1R	Sigma Receptor	Neurological Disease
E1R is a positive allosteric modulator of sigma-1 receptors (Sig1R PAM) with cognition-enhancing activity .

HY-131914A

EST64454 hydrochloride	Sigma Receptor	Neurological Disease
EST64454 hydrochloride is a selective and orally active sigma-1 receptor antagonist with a K_i of 22 nM. EST64454 hydrochloride has the potential for the research of the pain .

HY-116594A

OPC-14523 hydrochloride	Sigma Receptor 5-HT Receptor	Neurological Disease
OPC-14523 hydrochloride is an orally active *sigma* and 5-HT1A receptor agonist, with high affinity for sigma receptors (σ1/2 IC₅₀=47/56 nM), the 5-HT1A receptor (IC₅₀=2.3 nM), and the 5-HT transporter (IC₅₀=80 nM). OPC-14523 hydrochloride shows antidepressant-like activity .

HY-16996A

BD-1047 dihydrobromide 5 Publications Verification	Sigma Receptor	Neurological Disease
BD-1047 (dihydrobromide) is a selective functional antagonist of sigma-1 receptor, shows antipsychotic activity in animal models predictive of efficacy in schizophrenia .

HY-136280

Panamesine EMD 57445	Sigma Receptor	Neurological Disease
Panamesine (EMD 57445) is a sigma receptor ligand, which has a high affinity (IC₅₀ 6 nM) and selectivity for sigma binding sites. Panamesine is a potential atypical neuroleptic agent .

HY-134189

EST73502	Opioid Receptor Sigma Receptor	Neurological Disease
EST73502 is a selective, orally active and blood-brain barrier (BBB) penetrant dual μ-opioid receptor (MOR) agonist and σ1 receptor (σ1R) antagonist, with K_is of 64 nM and 118 nM for MOR and σ1R, respectively. EST73502 has antinociceptive activity .

HY-B1733

Phenyltoloxamine Bistrimin; Histionex	Histamine Receptor Sigma Receptor Cytochrome P450	Neurological Disease Inflammation/Immunology
Phenyltoloxamine (Bistrimin) is an antihistamine agent with sedative and analgesic effects. Phenyltoloxamine also has potent Sigma-1 receptor binding affinity (K_i: 160 nM) .

Species:	Human (2) Mouse (2)
Tag:	His (2) Tag Free (2) Myc (1)
Source:	HEK293 (1) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P74438

	*14-3-3 sigma* Protein, Mouse** 14-3-3 protein Sigma; HME1; SFN; Stratifin; Mkrn3	Mouse	E. coli
	14-3-3 sigma protein, an adapter in diverse signaling pathways, binds phosphoserine or phosphothreonine motifs, modulating partner activity. It regulates protein synthesis and cell growth via Akt/mTOR pathway stimulation when bound to KRT17. It may also regulate MDM2 autoubiquitination, activating p53/TP53. Existing as a homodimer, it interacts with GAB2, KRT17, SAMSN1, SRPK2, COPS6, COP1 (for degradation), phosphorylated DAPK2, PI4KB, SLITRK1, and LRRK2 (phosphorylation-dependent). Complexes include XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, and VPS35. 14-3-3 sigma Protein, Mouse is the recombinant mouse-derived 14-3-3 sigma protein, expressed by E. coli, with tag free. The total length of 14-3-3 sigma Protein, Mouse is 248 a.a., with molecular weight of ~32 kDa.

HY-P71339

	Stratifin Protein, Human 1 Publications Verification 14-3-3 Protein Sigma; Epithelial Cell Marker Protein 1; Stratifin; SFN; HME1	Mouse	E. coli
	Stratifin (14-3-3 sigma), encoded by SFN, functions as a multifaceted adapter protein, engaging in diverse cellular processes by binding to partners via phosphoserine or phosphothreonine motifs. It regulates epithelial cell growth and protein synthesis with keratin 17 (KRT17) and potentially influences MDM2 autoubiquitination, activating p53. As a homodimer, it interacts in various complexes with proteins like GAB2, SAMSN1, SRPK2, COPS6, COP1, DAPK2, PI4KB, SLITRK1, and LRRK2, highlighting its versatile role in cellular processes and signaling pathways. Stratifin Protein, Human is the recombinant mouse-derived Stratifin protein, expressed by E. coli, with tag free. The total length of Stratifin Protein, Human is 248 a.a., with molecular weight of ~30.0 kDa.

HY-P7473

	ADH7 Protein, Human (HEK293, His) rHuADH7, His; Alcohol dehydrogenase class 4 mu, Sigma chain; ADH-7	Human	HEK293
	ADH7 Protein, Human (HEK293, His) is human recombinant ADH7 with His tag at the C-terminus. ADH7 Protein, Human (HEK293, His) is expressed by Mammalian expression system and the target gene encoding Met1-Phe386 is expressed.

HY-P700308

	Stratifin Protein, Human (N-His, C-Myc) 14-3-3 Protein Sigma; Epithelial Cell Marker Protein 1; Stratifin; SFN; HME1	Human	E. coli
	Stratifin (14-3-3 sigma), encoded by SFN, functions as a multifaceted adapter protein, engaging in diverse cellular processes by binding to partners via phosphoserine or phosphothreonine motifs. It regulates epithelial cell growth and protein synthesis with keratin 17 (KRT17) and potentially influences MDM2 autoubiquitination, activating p53. As a homodimer, it interacts in various complexes with proteins like GAB2, SAMSN1, SRPK2, COPS6, COP1, DAPK2, PI4KB, SLITRK1, and LRRK2, highlighting its versatile role in cellular processes and signaling pathways. Stratifin Protein, Human (N-His, C-Myc) is the recombinant human-derived Stratifin protein, expressed by E. coli, with N-10*His, C-Myc labeled tag. The total length of Stratifin Protein, Human (N-His, C-Myc) is 248 a.a., with molecular weight of ~34 kDa.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks