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Source classification

" in MCE Product Catalog:

80

Inhibitors & Agonists

25

Screening Libraries

1

Fluorescent Dye

7

Biochemical Assay Reagents

6

Peptides

31

Natural
Products

20

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas
  • HY-W127808
    Mesobiliverdin (microbial source)

    Mesobiliverdin IX

    Others
    Mesobiliverdin (microbial source) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
  • HY-117293
    Phenyl sulfamate

    Others Others
    Phenyl sulfamate is a nitrogen source that can be used in the amination of intermolecular.
  • HY-130778
    N,N'-Diacetylchitobiose

    Others Endogenous Metabolite Others
    N,N'-Diacetylchitobiose is a dimer of β(1,4) linked N-acetyl-D glucosamine. N,N'-Diacetylchitobiose is the hydrolysate of chitin and can be used as alternative carbon source by E. coli.
  • HY-P1206
    CH 275

    Somatostatin Receptor Neurological Disease
    CH 275 is a peptide analog of somatostatin and binds preferably to somatostatin receptor 1 (sst1) with a Ki of 52 nM. CH 275 acts as a potent and selective sst1 agonist (IC50=30.9 nM) and also displays IC50 values of 345 nM, >1 μM, >10 μM, >10 μM for human sst3, sst4, sst2 and sst5, respectively. CH 275 can be used for the research of alzheimer’s disease.
  • HY-N2024A
    Maltose monohydrate

    Endogenous Metabolite Cancer
    Maltose monohydrate is the energy source for bacteria.
  • HY-D0851
    Sodium molybdate

    Molybdate disodium

    Biochemical Assay Reagents Others
    Sodium molybdate (Molybdate disodium) is a useful source of molybdate.
  • HY-N1413
    Noricaritin

    Others Inflammation/Immunology Cancer
    Noricaritin is a flavonoid sourced from roots of Epimedium brevicornu Maxim.
  • HY-141577
    C12-NBD Sphinganine

    Biochemical Assay Reagents Others
    C12-NBD Sphinganine is a fluorescent ceramidase substrate. C12-NBD Sphinganine can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources.
  • HY-110092
    PSB-1114 tetrasodium

    P2Y Receptor Metabolic Disease
    PSB-1114 tetrasodium is a potent, enzymatically stable, and subtype-selective P2Y2 receptor agonist with an EC50 of 134 nM. PSB-1114 tetrasodium displays >50-fold selectivity versus the P2Y4 (EC50 of 9.3 μM) and P2Y6 (EC50 of 7.0 μM) receptors.
  • HY-B1000
    Selenomethionine

    Seleno-DL-methionine; DL-Selenomethionine

    Autophagy Endogenous Metabolite Cancer
    Selenomethionine is a naturally occurring amino acid containing selenium, is a common natural food source of selenium.
  • HY-N10856
    2H-1-Benzopyran-2-one, 6-[(1R,2S)-2,3-dihydroxy-1-methoxy-3-methylbutyl]-7-methoxy-

    Others Others
    6-[(1R,2S)-2,3-dihydroxy-1-methoxy-3-methylbutyl]-7-methoxy- can be isolated from Angelica dahurica stem, for the first time from a plant source.
  • HY-B2235
    Lecithin

    Endogenous Metabolite Others
    Lecithin is regarded as a safe, conventional phospholipid source. Phospholipids are reported to alter the fatty acid composition and microstructure of the membranes in animal cells.
  • HY-N2024AS
    Maltose monohydrate-d14

    Endogenous Metabolite Cancer
    Maltose monohydrate-d14 is the deuterium labeled Maltose monohydrate. Maltose monohydrate is the energy source for bacte[1][2].
  • HY-D0705
    Acid Yellow 9 monosodium salt

    Hydrogen 4-aminoazobenzene-3,4'-disulphonate sodium salt

    Fluorescent Dye Others
    Acid Yellow 9 monosodium salt is an azo dye, degraded by Pseudomonas fluorescens as sole source of carbon, nitrogen and energy for the bacterium.
  • HY-W000438
    N-Boc-O-tosyl hydroxylamine

    Amino Acid Derivatives Cancer
    N-Boc-O-tosyl hydroxylamine is used as a safe and efficient nitrogen source for the N-amination of aryl and alkyl amines.
  • HY-N2550A
    (+)-Coclaurine hydrochloride

    (+)-(R)-Coclaurine hydrochloride; (R)-Coclaurine hydrochloride; d-Coclaurine hydrochloride

    Others Neurological Disease
    (+)-Coclaurine ((+)-(R)-Coclaurine) hydrochloride, benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+)-Coclaurine hydrochloride has anti-aging activity.
  • HY-76542
    Vitamin D2

    Ergocalciferol; Calciferol; Ercalciol

    VD/VDR Endogenous Metabolite Metabolic Disease
    Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D.
  • HY-N2550
    (+)-Coclaurine

    (+)-(R)-Coclaurine; (R)-Coclaurine; d-Coclaurine

    Others Neurological Disease
    (+)-Coclaurine ((+)-(R)-Coclaurine), benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+)-Coclaurine has anti-aging activity.
  • HY-B2203
    Calcium glycerophosphate

    Phosphatase Metabolic Disease
    Calcium glycerophosphate is an inhibitor of intestinal alkaline phosphatase F3. Calcium glycerophosphate is a source of calcium and phosphorus in total parenteral nutrition solutions.
  • HY-135053
    Autotaxin-IN-3

    Phosphodiesterase (PDE) Inflammation/Immunology
    Autotaxin-IN-3 is a Autotaxin(ATX) inhibitor with an IC50 of 2.4 nM, compound 33, sourced from patent WO2018212534A1.
  • HY-N2487
    5-Hydroxy-7-acetoxyflavone

    Others Cancer
    5-Hydroxy-7-acetoxyflavone, an active natural flavone derivative found in various plant sources, modulates several biological activities.
  • HY-128934
    Antitumor agent-2

    Others Cancer Inflammation/Immunology
    Antitumor agent-2 is sourced from patent CN102250203, compound 6a-r, has antitumor action and anti-inflammatory action.
  • HY-B2227A
    Lactate calcium

    Lactic acid calcium

    Bacterial Cancer
    Lactate (Lactic acid) calcium is used by the beverage industry as a source of calcium to fortify fruit juice. Lactate calcium facilitates the growth and phytic acid degradation of soybean sprouts.
  • HY-N7079A
    Sodium erythorbate

    D-Isoascorbic acid sodium; D-Araboascorbic acid sodium

    Biochemical Assay Reagents Cancer
    Sodium erythorbate (D-Isoascorbic acid sodium), produced from sugars derived from different sources, such as beets, sugar cane, and corn, is a food additive used predominantly in meats, poultry, and soft drinks.
  • HY-N7079
    Erythorbic acid

    D-Isoascorbic acid; D-Araboascorbic acid

    Biochemical Assay Reagents Others
    Erythorbic acid (D-Isoascorbic acid), produced from sugars derived from different sources, such as beets, sugar cane, and corn, is a food additive used predominantly in meats, poultry, and soft drinks.
  • HY-16686
    α-Tocopherol phosphate

    alpha-Tocopherol phosphate; TocP; vitamin E phosphate

    Others Others
    α-Tocopherol phosphate is the compound demonstrating the highest vitamin E activity, which is available both in its natural form as RRR-alpha-tocopherol isolated from plant sources.
  • HY-N2024
    Maltose

    Endogenous Metabolite Metabolic Disease Cancer
    Maltose is a disaccharide formed from two units of glucose joined with an α(1→4) bond, a reducing sugar. Maltose monohydrate can be used as a energy source for bacteria.
  • HY-B0952
    2-Aminoheptane

    1-Methylhexylamine; 2-Heptylamine

    Others Neurological Disease
    2-Aminoheptane (1-Methylhexylamine) is an isomeric heptylamine commonly used as stimulant. 2-Aminoheptane can be used as the nitrogen source in minimal medium.
  • HY-N7124
    Benzyl acetate

    Others Others
    Benzyl acetate is a constituent of jasmin and of the essential oils of ylang-ylang and neroli. Natural sources of Benzyl acetate include varieties of flowers like jasmine (Jasminum), and fruits like pear, apple.
  • HY-128876
    CBP/p300-IN-3

    Histone Acetyltransferase Cancer
    CBP/p300-IN-3, a p300/CBP histone acetyltransferase inhibitor, Compound 6, is sourced from patent WO 2019049061 A1.
  • HY-77490A
    1,3-Butanediol

    Endogenous Metabolite Neurological Disease Cardiovascular Disease
    1,3-Butanediol, an ethanol dimer providing a source of calories for human nutrition. 1,3-Butanediol is converted in the body to β-hydroxybutyrate and has cerebral protective and hypoglycaemic effect.
  • HY-113447
    11-Dehydrocorticosterone

    Endogenous Metabolite Metabolic Disease Cardiovascular Disease
    11-Dehydrocorticosterone is a endogenous corticosteroid. 11-Dehydrocorticosterone can be a source of transcriptionally active glucocorticoid in cardiac myocytes and fibroblasts. 11-Dehydrocorticosterone can increase SGK mRNA expression in cardiac fibroblast.
  • HY-W071746
    Linolelaidic acid

    Linoelaidic acid

    Endogenous Metabolite Cardiovascular Disease
    Linolelaidic acid (Linoelaidic acid), an omega-6 trans fatty acid, acts as a source of energy. Linolelaidic acid is an essential nutrient, adding in enteral, parenteral, and infant formulas. Linolelaidic acid can be used for heart diseases research.
  • HY-N0390
    L-Glutamine

    L-Glutamic acid 5-amide

    mGluR Endogenous Metabolite Ferroptosis Metabolic Disease Cancer
    L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.
  • HY-Y0032
    Thiosemicarbazide

    Orthopoxvirus Infection
    Thiosemicarbazide is well-known source in heterocyclic synthesis. Thiosemicarbazide has also been utilized for spectrophotometric detection of metals, gadget applications with respect to media communications and optical storage. Thiosemicarbazide shows anti-orthopoxvirus activity.
  • HY-W051723
    (R)-3-Hydroxybutanoic acid

    (R)-(-)-3-Hydroxybutanoic acid; (R)-3-Hydroxybutyric acid

    Endogenous Metabolite Others
    (R)-3-Hydroxybutanoic acid is a metabolite, and converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid has applications as a nutrition source and as a precursor for vitamins, antibiotics and pheromones.
  • HY-76542S
    Vitamin D2-d6

    Ergocalciferol-d6; Calciferol-d6; Ercalciol-d6

    VD/VDR Endogenous Metabolite Metabolic Disease
    Vitamin D2-d6 is the deuterium labeled Vitamin D2. Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D[1][2].
  • HY-W010378
    D-Asparagine

    H-D-Asn-OH

    Endogenous Metabolite Metabolic Disease
    D-Asparagine (H-D-Asn-OH) is a competitive inhibitor of L-Asparagine hydrolysis with a Ki value of 0.24 mM. D-Asparagine is a source of nitrogen for yeast strains. D-Asparagine is a good substrate for the external yeast asparaginase but is a poor substrate for the internal enzyme.
  • HY-W050031
    (S)-3-Hydroxybutanoic acid

    (S)-β-Hydroxybutanoic acid; L-(+)-3-Hydroxybutyric acid; L-β-Hydroxybutyric acid

    Endogenous Metabolite Others
    (S)-3-Hydroxybutanoic acid is a normal human metabolite, that has been found elevated in geriatric patients remitting from depression. In humans, 3-Hydroxybutyric acid is synthesized in the liver from acetyl-CoA, and can be used as an energy source by the brain when blood glucose is low.
  • HY-W015851
    (R)-3-Hydroxybutanoic acid sodium

    (R)-(-)-3-Hydroxybutanoic acid sodium; (R)-3-Hydroxybutyric acid sodium

    Endogenous Metabolite Metabolic Disease
    (R)-3-Hydroxybutanoic acid sodium ((R)-3-Hydroxybutyric acid) is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones.
  • HY-135087
    Caprylic/Capric Triglyceride

    Biochemical Assay Reagents Others
    Caprylic/Capric Triglyceride is the triglycerides and esters prepared from fractionated vegetable oil sources and fatty acids from coconuts and palm kernel oils. Caprylic/Capric Triglyceride possesses excellent oxidation stability. Caprylic/Capric Triglyceride is used as a food additive and used in cosmetics.
  • HY-W250315
    Polypectate sodium

    pectate sodium

    Others Others
    Polypectate sodium is a major component of cell wall polysaccharides (pectins) and is used as a carbon source and inducer of polygalacturonase. Polypectate sodium can also be used to evaluate alkaline active and alkaline stable pectate lyases from Streptomyces spp. and to study the optimization of polygalacturonase production from Xanthophyllum spp. and reaction conditions.
  • HY-N0390S2
    L-Glutamine-d5

    L-Glutamic acid 5-amide-d5

    mGluR Endogenous Metabolite Ferroptosis Metabolic Disease
    L-Glutamine-d5 is the deuterium labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
  • HY-N0390S
    L-Glutamine-15N

    L-Glutamic acid 5-amide-15N

    mGluR Endogenous Metabolite Ferroptosis Metabolic Disease
    L-Glutamine- 15N is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
  • HY-N11386
    Harpactira Hamiltoni Venom

    Highveld Baboon Spider Venom

    Others Neurological Disease
    Harpactira Hamiltoni Venom (Highveld Baboon Spider Venom) is a venom that can be obtained from baboon spider. Spider venoms are complex mixtures of neurotoxic peptides, proteins and low molecular mass organic molecules. Spider venoms have proven to be a rich source of highly specific peptide ligands for selected subtypes of potassium, sodium and calcium channels.
  • HY-N0390S1
    L-Glutamine-13C5

    L-Glutamic acid 5-amide-13C5

    mGluR Endogenous Metabolite Ferroptosis Metabolic Disease
    L-Glutamine- 13C5 is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
  • HY-N0390S5
    L-Glutamine-1-13C

    L-Glutamic acid 5-amide-1-13C

    mGluR Endogenous Metabolite Ferroptosis Metabolic Disease
    L-Glutamine-1- 13C is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
  • HY-N0814B
    Phytic acid hexasodium

    Inositol hexaphosphate hexasodium

    Endogenous Metabolite Inflammation/Immunology Neurological Disease
    Phytic acid (Inositol hexaphosphate) hexasodium is a phosphorus storage compound of seeds and cereal grains. Phytic acid hexasodium has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid hexasodium inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.
  • HY-N0390S4
    L-Glutamine-5-13C

    L-Glutamic acid 5-amide-5-13C

    mGluR Endogenous Metabolite Ferroptosis Metabolic Disease
    L-Glutamine-5- 13C is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
  • HY-N0390S11
    L-Glutamine-2-13C

    L-Glutamic acid 5-amide-2-13C

    mGluR Endogenous Metabolite Ferroptosis Metabolic Disease
    L-Glutamine-2- 13C is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
  • HY-N0390S8
    L-Glutamine-15N2

    L-Glutamic acid 5-amide-15N2

    mGluR Endogenous Metabolite Ferroptosis Metabolic Disease
    L-Glutamine- 15N2 is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
  • HY-113629
    2-Keto-D-Glucose

    D-Glucosone; D-Arabino-hexos-2-ulose

    Drug Metabolite Infection
    2-Keto-D-Glucose (D-Glucosone) is a key intermediate in a secondary metabolic pathway leading to the antibiotic Cortalcerone. 2-Keto-D-Glucose is also an intermediate in the conversion of D-glucose into D-fructose. 2-Keto-D-Glucose is found in various natural sources, including fungi, algae, and shellfish.
  • HY-N0390S10
    L-Glutamine-1,2-13C2

    L-Glutamic acid 5-amide-1,2-13C2

    mGluR Endogenous Metabolite Ferroptosis Metabolic Disease
    L-Glutamine-1,2- 13C2 is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
  • HY-N0390S9
    L-Glutamine-15N-1

    L-Glutamic acid 5-amide-15N-1

    mGluR Endogenous Metabolite Ferroptosis Metabolic Disease
    L-Glutamine- 15N-1 is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
  • HY-Y0271
    Urea

    Carbamide; Carbonyldiamide; Carbonyl diamide

    Endogenous Metabolite Cardiovascular Disease Cancer
    Urea is a powerful protein denaturant via both direct and indirect mechanisms. A potent emollient and keratolytic agent. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
  • HY-N0390S6
    L-Glutamine-13C5,15N2

    L-Glutamic acid 5-amide-13C5,15N2

    mGluR Endogenous Metabolite Ferroptosis Metabolic Disease
    L-Glutamine- 13C5, 15N2 is the 13C- and 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
  • HY-N11387
    Harpactira Pulchripes Venom

    Golden Blue-Legged Venom

    Others Neurological Disease
    Harpactira Pulchripes Venom (Golden Blue-Legged Venom) is a venom that can be obtained from golden blue-legged baboon spider. Spider venoms are complex mixtures of neurotoxic peptides, proteins and low molecular mass organic molecules. Spider venoms have proven to be a rich source of highly specific peptide ligands for selected subtypes of potassium, sodium and calcium channels.
  • HY-N0390S7
    L-Glutamine-15N2,d5

    L-Glutamic acid 5-amide-15N2,d5

    mGluR Endogenous Metabolite Ferroptosis Metabolic Disease
    L-Glutamine- 15N2,d5 is the deuterium and 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
  • HY-N0814
    Phytic acid

    Inositol hexaphosphate

    Xanthine Oxidase Endogenous Metabolite Inflammation/Immunology Neurological Disease
    Phytic acid (Inositol hexaphosphate) is a phosphorus storage compound of seeds and cereal grains. Phytic acid is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.
  • HY-123033A
    Nicotinamide riboside chloride

    Sirtuin Endogenous Metabolite Metabolic Disease Neurological Disease Cancer
    Nicotinamide riboside Chloride, an orally active NAD + precursor, increases NAD + levels and activates SIRT1 and SIRT3. Nicotinamide riboside Chloride is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside Chloride reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease.
  • HY-P2902
    Glucose oxidase

    Endogenous Metabolite Cancer
    Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O2) to produce hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation.
  • HY-123033
    Nicotinamide riboside

    Sirtuin Endogenous Metabolite Metabolic Disease Neurological Disease Cancer
    Nicotinamide riboside, an orally active NAD + precursor, increases NAD + levels and activates SIRT1 and SIRT3. Nicotinamide riboside is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease.
  • HY-N0814A
    Phytic acid dodecasodium hydrate

    Inositol hexaphosphate dodecasodium hydrate

    Xanthine Oxidase Endogenous Metabolite Inflammation/Immunology Neurological Disease
    Phytic acid (Inositol hexaphosphate) dodecasodium hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid dodecasodium hydrate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.
  • HY-B1529A
    Citric acid triammonium

    Triammonium citrate

    Endogenous Metabolite Apoptosis Cancer Infection Metabolic Disease Inflammation/Immunology Cardiovascular Disease
    Citric acid triammonium (Triammonium citrate) is formed by Citric acid (HY-N1428) reacting with ammonia in a molar ratio of 1:3. Citric acid triammonium can be used as the carbon source to prepare carbon quantum dots (CDs). Citric acid triammonium with higher nitrogen components might promote the nitrogen-based functional groups in CDs, leading to a more efficient emission-color tunability.
  • HY-B0717
    Tocofersolan

    TPGS; D-α-Tocopherol polyethylene glycol 1000 succinate; Vitamin E-TPGS

    Others Metabolic Disease Neurological Disease
    Tocofersolan is synthetic polyethylene glycol derivative of α-tocopherol. Tocofersolan is an orally active and water-soluble analog of vitamin E. Tocofersolan can reduce neurobehavioral deficits in zebrafish embryos exposed to moderate and high concentrations of BaP during early development. Tocofersolan shows antioxidant activity. Tocofersolan can be used to provide an orally bioavailable source of vitamin E.
  • HY-N0390S3
    L-Glutamine-13C5,15N2,d5

    L-Glutamic acid 5-amide-13C5,15N2,d5

    mGluR Endogenous Metabolite Ferroptosis Metabolic Disease
    L-Glutamine- 13C5, 15N2,d5 is the deuterium, 13C-, and 15-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
  • HY-123033B
    Nicotinamide riboside tartrate

    Sirtuin Endogenous Metabolite Metabolic Disease Neurological Disease Cancer
    Nicotinamide riboside tartrate, an orally active NAD + precursor, increases NAD + levels and activates SIRT1 and SIRT3. Nicotinamide riboside tartrate is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside tartrate reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease.
  • HY-123033C
    Nicotinamide riboside malate

    Sirtuin Endogenous Metabolite Metabolic Disease Neurological Disease Cancer
    Nicotinamide riboside malate, an orally active NAD + precursor, increases NAD + levels and activates SIRT1 and SIRT3. Nicotinamide riboside malate is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside malate reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease.
  • HY-Y0271S
    Urea-15N2

    Carbamide-15N2; Carbonyldiamide-15N2

    Endogenous Metabolite Cardiovascular Disease Cancer
    Urea- 15N2 is the 15N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
  • HY-B0228S10
    (R)-3-Hydroxybutanoic acid-13C2 sodium

    (R)-(-)-3-Hydroxybutanoic acid-13C2 (sodium); (R)-3-Hydroxybutyric acid-13C2 (sodium)

    Endogenous Metabolite Metabolic Disease
    (R)-3-Hydroxybutanoic acid- 13C2 (sodium) is the 13C labeled (R)-3-Hydroxybutanoic acid (sodium) (HY-W015851). (R)-3-Hydroxybutanoic acid (sodium) is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones[1][2][3].
  • HY-Y0271S1
    Urea-d4

    1,1,3,3-Tetradeuteriourea; Urea-d4

    Endogenous Metabolite
    Urea-d4 is the deuterium labeled Urea[1]. Urea is a powerful protein denaturant via both direct and indirect mechanisms[2]. A potent emollient and keratolytic agent[3]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[4]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
  • HY-125863
    Glucose-6-phosphate dehydrogenase

    Endogenous Metabolite Cancer Metabolic Disease
    Glucose-6-phosphate dehydrogenase is the rate-limiting enzyme of the pentose phosphate pathway. Glucose-6-phosphate dehydrogenase is a major source of NADPH that is required by many essential cellular systems including the antioxidant pathways, nitric oxide synthase, NADPH oxidase, cytochrome p450 system, and others. Glucose-6-phosphate dehydrogenase can be used for the research of diabetes, aldosterone-induced endothelial dysfunction, and cancer.
  • HY-W015851S
    (R)-3-Hydroxybutanoic acid-13c sodium

    [2-13C]Sodium acetate; Sodium [2-13C]acetate; Sodium acetate-2-13C

    Endogenous Metabolite Metabolic Disease
    (R)-3-Hydroxybutanoic acid- 13C (sodium) is the 13C labeled (R)-3-Hydroxybutanoic acid sodium[1]. (R)-3-Hydroxybutanoic acid sodium ((R)-3-Hydroxybutyric acid) is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones[2][3].
  • HY-141572
    1,2-Dioleoyl-sn-glycerol

    sn-1,2-dioleoylglycerol

    Others
    ALN29882 is a glycerolipid located on the plasma membrane. It consists of two fatty acid chains covalently linked to a single glycerol molecule by means of an ester bond. 18:1 DG has been used as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay. It is also used as a substrate in the DGAT-1 enzyme assay to evaluate compounds as potential inhibitors of DGAT-1. Suitable for lipoprotein overlay screening assays with the recombinant protein His-AtROP6.
  • HY-Y0271S2
    Urea-13C,15N2

    Endogenous Metabolite
    Urea- 13C, 15N2 is the 13C and 15N labeled Urea[1]. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
  • HY-N0407
    Picroside I

    6'-Cinnamoylcatalpol

    STAT Inflammation/Immunology
    Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II. Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ.
  • HY-125139
    omega-3 Arachidonic Acid ethyl ester

    ethyl (8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoate

    Others
    omega-3 Arachidonic Acid ethyl ester is a rare polyunsaturated fatty acid found in very small amounts in dietary sources. Omega-3 fatty acids are known to be essential for the growth and development of infants, and they protect against heart disease, blood clots, high blood pressure, and inflammatory and autoimmune diseases. In human platelet membranes, omega-3 arachidonic acid inhibits arachidonyl-CoA synthetase with a Ki of 14 μM. It also inhibits arachidonoyl-CoA synthetase in calf brain extract with an IC50 of approximately 5 μM. Omega-3 ethyl arachidonate is the more lipophilic form of the free acid.
  • HY-15344
    (R,R)-BD-AcAc 2

    (R,R)-Ketone Ester

    Others Metabolic Disease Neurological Disease
    (R,R)-BD-AcAc 2 ((R,R)-Ketone Ester), a ketone monoester, can be used as a source of oral nutritional ketones. (R,R)-BD-AcAc 2 can elevate plasma levels of β-hydroxybutyrate and acetoacetate, blood glucose, blood Na + levels and blood creatinine levels after oral administration in mice. (R,R)-BD-AcAc 2 can partly prevent muscle weakness in septic mice. (R,R)-BD-AcAc 2 has potential to improve exercise performance and endurance in animal body. (R,R)-BD-AcAc 2 can also be used to research Parkinson’s disease or diabetes.
  • HY-W127357
    Glyceryl trinonanoate

    Tripelargonin

    Others
    Glyceryl trinonanoate is a triacylglycerol containing nonanoic acid at the sn-1, sn-2 and sn-3 positions. It has been found in Schizochytrium biomass. 1 1,2,3-Trinonanoyl-rac-glycerol increases blood levels of the ketone body D-(-)-3-hydroxybutyrate in neonatal rhesus monkeys. 2|1. Mioso, R., Toledo Marante, FJ, González, JE, et al. Schizochytrium sp. metabolite analysis. Oleaginous microbial sources of biodiesel by GC-MS. braz. J. Microbiology. 45(2), 403-409 (2014).|2. Tetrick, MA, Greer, FR and Benevenga, NJ Blood D- (?)-3-Hydroxybutyric acid concentration. Compare. medicine. 60(6), 486-490 (2010).
  • HY-N5072
    Desmethylglycitein

    4',6,7-Trihydroxyisoflavone

    CDK PI3K PKC Cancer
    Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities. Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity. Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1). Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes.