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Results for "

Spermine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (2) Amyloid-β (1) Caspase (1) Endogenous Metabolite (3) Histone Demethylase (1) ICMT (1) iGluR (2) Isotope-Labeled Compounds (1) Liposome (2) Parasite (2)
By Research Areas:	Cancer (7) Cardiovascular Disease (2) Infection (2) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (4)
Click Chemistry:	Azide (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1777

*Spermine* 3 Publications Verification NSC 268508; Neuridine
Spermine (NSC 268508) functions directly as a free radical scabenger to protect DNA from free radical attack. Spermine has antiviral effects.

HY-101394

Spermine NONOate

Spermine NONOate is a complex of nitric oxide (NO) with spermine and acts as a NO donor. Spermine NONOate can be used for NO aqueous solutions preparing .

Spermine NONOate
Spermine NONOate is a complex of nitric oxide (NO) with spermine and acts as a NO donor. Spermine NONOate can be used for NO aqueous solutions preparing .

HY-151717

*N1-Azido-spermine* trihydrochloride** Spermine(HHHN3) trihydrochloride	ADC Linker	Others
N1-Azido-spermine [Spermine(HHHN3)] trihydrochloride is a click chemistry agent containing azide.

HY-139995

Spermine Prodrug-1	Others	Others
Spermine precursor-1 (Compound 1) is a redox-sensitive spermine precursor for the potential research of snyder robinson syndrome. Spermine precursor-1 inhibits wild-type (CMS-24949) and spermine synthase gene (SMS) mutant (CMS-26559, and CMS-6233) fibroblast cells with IC₅₀s of 326.7, 198.5, and 244.1 μM, respectively .

HY-B1777AS

Spermine-d8 tetrahydrochloride	Endogenous Metabolite	Metabolic Disease
Spermine-d₈ (tetrahydrochloride) is the deuterium labeled Spermine tetrahydrochloride. Spermine tetrahydrochloride is an endogenous metabolite.

HY-B1777A

Spermine tetrahydrochloride

3 Publications Verification

Spermine tetrahydrochloride is an endogenous metabolite.
HY-151657

Spermine(N3BBB)

ADC Linker Others

Spermine(N3BBB) is a click chemistry reagent containing an azide group and can be used for various biochemical studies .

Spermine tetrahydrochloride 3 Publications Verification
Spermine tetrahydrochloride is an endogenous metabolite.

Spermine(N3BBB)	ADC Linker	Others
Spermine(N3BBB) is a click chemistry reagent containing an azide group and can be used for various biochemical studies .

HY-149037

GL67 N4-Spermine cholesteryl carbamate	Liposome	Others
GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .

HY-12506A

Naspm trihydrochloride Maximum Cited Publications 7 Publications Verification 1-Naphthylacetyl Spermine trihydrochloride	iGluR	Neurological Disease
Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.

HY-144752

cSPM Cyclic Spermine	Amyloid-β	Neurological Disease
cSPM (Cyclic spermine) is a Aβ42 inhibitor. cSPM could suppress the aggregation of three different peptides, Aβ42, amylin and insulin, and decreases cytotoxicity .

HY-12506

Naspm Maximum Cited Publications 7 Publications Verification 1-Naphthylacetyl Spermine	iGluR	Neurological Disease
Naspm (1-Naphthyl acetyl spermine), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.

HY-149037A

GL67 pentahydrochloride N4-Spermine cholesteryl carbamate pentahydrochloride	Liposome	Others
GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .

HY-151115

JNJ-1289	Others	Inflammation/Immunology Cancer
JNJ-1289 is a potent, selective, competitive and allosteric *human spermine* oxidase (hSMOX) inhibitor (IC₅₀**: 50 nM). JNJ-1289 can be used in the research of polyamine catabolism, inflammation and cancers .

HY-13610

N1,N11-Diethylnorspermine	Caspase	Cancer
N1,N11-Diethylnorspermine (DENSPM) is a potent anticancer agent. N1,N11-Diethylnorspermine is a spermine analog that activates polyamine catabolism. N1,N11-Diethylnorspermine induces the release of cytochrome c from mitochondria, resulting in activation of caspase 3. N1,N11-Diethylnorspermine kills glioblastoma multiforme (GBM) cells through induction of SSAT (spermidine/spermine N1-acetyltransferase) coupled with H2O2 production .

HY-132822

Ivospemin

SBP-101
Others Cancer

Ivospemin is an antineoplastic spermine analog .

Ivospemin SBP-101	Others	Cancer
Ivospemin is an antineoplastic spermine analog .

HY-N2392

Kukoamine A 1 Publications Verification	Parasite	Infection Cardiovascular Disease
Kukoamine A is a natural occurring spermine derivative, acts as a potent inhibitor of trypanothione reductase (K_i, 1.8 μM), with antihypertensive activity .

HY-149712

Spermatinamine	ICMT	Cancer
Spermatinamine is a novel alkaloid with a bromotyrosyl-spermine-bromotyrosyl sequence, and a natural ICMT inhibitor. Spermatinamine can be isolated from the Australian sponge Pseudoceratina .

HY-W007856

5-Methoxysalicylic acid 5-MeOSA	Endogenous Metabolite	Others
5-Methoxysalicylic acid (5-MeOSA) is a natural compound, used as a useful matrix in the MALDI MS analysis of oligonucleotides when combined with spermine .

HY-151224

Thermospermine	Others	Others
Thermospermine, a structural isomer of Spermine, is synthesized by a thermospermine synthase designated ACAULIS5 (ACL5). Thermospermine suppresses auxin-inducible xylem differentiation in Arabidopsis thaliana .

HY-16394

PG-11047 tetrahydrochloride CGC-11047 tetrahydrochloride	Others	Cancer
PG-11047 (CGC-11047), a polyamine analogue, is a nonfunctional competitor of the natural polyamine spermine. PG-11047 has broad spectrum anticancer activities .

HY-N2392S

Kukoamine A-d8 dihydrochloride	Isotope-Labeled Compounds Parasite	Infection Cardiovascular Disease
Kukoamine A-d₈ (dihydrochloride) is deuterium labeled Kukoamine A. Kukoamine A is a natural occurring spermine derivative, acts as a potent inhibitor of trypanothione reductase (Ki, 1.8 μM), with antihypertensive activity[1].

HY-W015514

N-(3-Aminopropyl)cyclohexylamine	Others	Neurological Disease
N-(3-Aminopropyl)cyclohexylamine, a cyclohexylamine derivative, acts as a selective and competitive inhibitor of spermine synthase. N-(3-Aminopropyl)cyclohexylamine can be used for the research of neurological diseases .

HY-13610A

N1,N11-Diethylnorspermine tetrahydrochloride 2 Publications Verification DENSPM tetrahydrochloride; BENSPM tetrahydrochloride
N1,N11-Diethylnorspermine tetrahydrochloride (DENSPM tetrahydrochloride) potently induces *SSAT (spermidine/spermine* N ¹-acetyltransferase)** mRNA and effectively stabilizes SSAT enzyme activity .

HY-113374A

N1,N12-Diacetylspermine dihydrochloride	Endogenous Metabolite	Cancer
N1,N12-Diacetylspermine dihydrochloride is a diacetylated derivative of Spermine. Upregulation of N1,N12-Diacetylspermine dihydrochloride has been linked to the incidence of cancer, making it to be a potential biomarker for cancer detection.

HY-Q36392

JNJ-9350 1 Publications Verification	Histone Demethylase	Cancer
JNJ-9350 is an inhibitor of spermine oxidase (SMOX) with an IC₅₀ value of 0.01 μM. JNJ-9350 also inhibits polyamine oxidase (PAO) with an IC₅₀ value of 0.79 μM. JNJ-9350 can be used for the research of cancer .

GL67 pentahydrochloride N4-Spermine cholesteryl carbamate pentahydrochloride	Drug Delivery
GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .

GL67 N4-Spermine cholesteryl carbamate	Drug Delivery
GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2392

Kukoamine A 1 Publications Verification	Cardiovascular Disease Alkaloids other families Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields	Parasite
Kukoamine A is a natural occurring spermine derivative, acts as a potent inhibitor of trypanothione reductase (K_i, 1.8 μM), with antihypertensive activity .

HY-W007856

5-Methoxysalicylic acid 5-MeOSA	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Flacourtiaceae Plants Disease Research Fields Xylosma racemosum (Sieb. et Zucc.) Miq.	Endogenous Metabolite
5-Methoxysalicylic acid (5-MeOSA) is a natural compound, used as a useful matrix in the MALDI MS analysis of oligonucleotides when combined with spermine .

HY-113374A

N1,N12-Diacetylspermine dihydrochloride	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
N1,N12-Diacetylspermine dihydrochloride is a diacetylated derivative of Spermine. Upregulation of N1,N12-Diacetylspermine dihydrochloride has been linked to the incidence of cancer, making it to be a potential biomarker for cancer detection.

Cat. No.	Product Name	Chemical Structure

HY-B1777AS

Spermine-d8 tetrahydrochloride

Spermine-d₈ (tetrahydrochloride) is the deuterium labeled Spermine tetrahydrochloride. Spermine tetrahydrochloride is an endogenous metabolite.

Spermine-d8 tetrahydrochloride
Spermine-d₈ (tetrahydrochloride) is the deuterium labeled Spermine tetrahydrochloride. Spermine tetrahydrochloride is an endogenous metabolite.

HY-N2392S

Kukoamine A-d8 dihydrochloride
Kukoamine A-d₈ (dihydrochloride) is deuterium labeled Kukoamine A. Kukoamine A is a natural occurring spermine derivative, acts as a potent inhibitor of trypanothione reductase (Ki, 1.8 μM), with antihypertensive activity[1].

*N1-Azido-spermine* trihydrochloride** Spermine(HHHN3) trihydrochloride		Azide
N1-Azido-spermine [Spermine(HHHN3)] trihydrochloride is a click chemistry agent containing azide.

Spermine(N3BBB)		Azide
Spermine(N3BBB) is a click chemistry reagent containing an azide group and can be used for various biochemical studies .

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Spermine

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Natural
Products