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Results for "

Sulfide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (1) Antibiotic (1) Apoptosis (2) Arp2/3 Complex (1) Bacterial (6) Biochemical Assay Reagents (2) Cuproptosis (1) Drug Metabolite (2) Endogenous Metabolite (1) Fluorescent Dye (3) Melanocortin Receptor (2) NF-κB (1) PD-1/PD-L1 (2) Phosphodiesterase (PDE) (1) Phospholipase (1) Prostaglandin Receptor (1) Proton Pump (3) Reactive Oxygen Species (1) Vasopressin Receptor (1) γ-secretase (2)
By Research Areas:	Cancer (5) Cardiovascular Disease (5) Endocrinology (1) Infection (6) Inflammation/Immunology (4) Metabolic Disease (2) Neurological Disease (9)
Click Chemistry:	Azide (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W013186S

*Lansoprazole sulfide-d4*	Proton Pump Bacterial	Inflammation/Immunology
Lansoprazole sulfide-d₄ is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 µM intracellularly and 0.46 µM in broth[1].

HY-128447

Allyl methyl sulfide	Bacterial Endogenous Metabolite	Infection Cancer
Allyl methyl sulfide is a bioactive organosulfur compound found in garlic. Allyl methyl sulfide exhibits antibacterial, antioxidant and anticancer properties .

HY-B1786A

(E/Z)-Sulindac sulfide	γ-secretase Amyloid-β	Neurological Disease
(E/Z)-Sulindac sulfide is a potent γ-secretase modulator (GSM). (E/Z)-Sulindac sulfide selectively reduces Aβ42 production in favor of shorter Aβ species. (E/Z)-Sulindac sulfide can be used for researching Alzheimer’s disease .

HY-B1786S

*Sulindac sulfide-d3* cis-Sulindac Sulfide-d₃	γ-secretase	Neurological Disease
Sulindac sulfide-d₃ is deuterium labeled Sulindac sulfide. Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.

HY-W003467R

*Rabeprazole Sulfide* (Standard)**	Proton Pump Bacterial	Infection Inflammation/Immunology
Rabeprazole Sulfide (Standard) is the analytical standard of Rabeprazole Sulfide. This product is intended for research and analytical applications. Rabeprazole Sulfide is an active metabolite of Rabeprazole. Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion through an interaction with (H ⁺/K ⁺)-ATPase in gastric parietal cells. Rabeprazole markedly inhibits the motility of *H. pylori*. Rabeprazole has the potential for various peptic diseases treatment .

HY-B1786

Sulindac sulfide

cis-Sulindac Sulfide

Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC₅₀ of 20.2 μM for γ₄₂-secretase activity.

Sulindac sulfide cis-Sulindac Sulfide
Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC₅₀ of 20.2 μM for γ₄₂-secretase activity.

HY-141776S

*Omeprazole sulfide-d3* Ufiprazole-d₃	Drug Metabolite	Others
Omeprazole sulfide-d₃ is the deuterium labeled Omeprazole sulfide. Omeprazole metabolite Omeprazole sulfide (Ufiprazole) is a metabolite of Omeprazole, which is a proton pump inhibitor.

HY-W250123

Dibutyl sulfide	Biochemical Assay Reagents	Others
Dibutyl sulfide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-G0006

Omeprazole sulfide

Ufiprazole
Drug Metabolite Others

Omeprazole metabolite Omeprazole sulfide (Ufiprazole) is a metabolite of Omeprazole, which is a proton pump inhibitor.

Omeprazole sulfide Ufiprazole	Drug Metabolite	Others
Omeprazole metabolite Omeprazole sulfide (Ufiprazole) is a metabolite of Omeprazole, which is a proton pump inhibitor.

HY-W003467

Rabeprazole Sulfide	Proton Pump Bacterial	Infection Inflammation/Immunology
Rabeprazole Sulfide is an active metabolite of Rabeprazole. Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion through an interaction with (H ⁺/K ⁺)-ATPase in gastric parietal cells. Rabeprazole markedly inhibits the motility of *H. pylori*. Rabeprazole has the potential for various peptic diseases treatment .

HY-W103170

1,8-Dichloroanthraquinone

Bacterial Others

1,8-Dichloroanthraquinone, an anthraquinone, is an inhibitor of sulfide production by sulfate-reducing bacteria .

1,8-Dichloroanthraquinone	Bacterial	Others
1,8-Dichloroanthraquinone, an anthraquinone, is an inhibitor of sulfide production by sulfate-reducing bacteria .

HY-100287

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide	Prostaglandin Receptor Phospholipase	Endocrinology
2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress.

HY-W076067

Ammonium tetrathiomolybdate(VI) 2 Publications Verification	Cuproptosis Others	Neurological Disease
Ammonium tetrathiomolybdate(VI) is a copper chelator and also is a class of sulfide donor. Ammonium tetrathiomolybdate(VI) has neuroprotection effects. Ammonium tetrathiomolybdate(VI) can be used for the research of brain ischemia .

HY-P2031

Phallacidin

Arp2/3 Complex Others

Phallacidin is a member of the phallotoxin family of mushroom toxins. Phallacidin binds F-actin .

Phallacidin	Arp2/3 Complex	Others
Phallacidin is a member of the phallotoxin family of mushroom toxins. Phallacidin binds F-actin .

HY-P0028

Phalloidin Maximum Cited Publications 9 Publications Verification	Fluorescent Dye	Others
Phalloidin is a mushroom-derived toxin which can be used to label F-actin of the cytoskeleton with fluorochrome .

HY-P3143

BMSpep-57	PD-1/PD-L1	Cancer
BMSpep-57 is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC₅₀ of 7.68 nM. BMSpep-57 binds to PD-L1 with K_ds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 facilitates T cell function by in creasing IL-2 production in PBMCs .

HY-P3143A

BMSpep-57 hydrochloride	PD-1/PD-L1	Cancer
BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC₅₀ of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with K_ds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs .

HY-D1275

CAY10731	Fluorescent Dye	Others
CAY10731 (compound 3) is a highly selective fluorescent probe for detection of hydrogen sulfide (H₂S). CAY10731 is used to monitor exo- and endogenous H₂S in both cancer and normal cells. CAY10731 is applied for imaging of H₂S in living tissues at variable depths and in nematodes .

HY-P0041A

F992 TFA

Vasopressin Receptor Neurological Disease

F992 TFA is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .

F992 TFA	Vasopressin Receptor	Neurological Disease
F992 TFA is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .

HY-126124

AP39 2 Publications Verification	Others	Cardiovascular Disease Neurological Disease
AP39 is a triphenylphosphonium derivatised anethole dithiolethione and mitochondria-targeting hydrogen sulfide (H₂S) donor. AP39 increases intracellular H₂S levels. AP39 exerts cytoprotective effects and maintains mitochondrial DNA integrity under oxidative stress conditions. AP39 protects against myocardial reperfusion injury in mice model and has the potential for Alzheimer's disease research .

HY-B0973

Dibenzothiophene

DBT; Diphenylene Sulfide
Others Others

Dibenzothiophene is an organic synthesis intermediate consisting of two benzene rings fused to a central thiophene ring.

Dibenzothiophene DBT; Diphenylene Sulfide	Others	Others
Dibenzothiophene is an organic synthesis intermediate consisting of two benzene rings fused to a central thiophene ring.

HY-144439

HTS07545	Others	Cardiovascular Disease
HTS07545 is a potent sulfide:quinone oxidoreductase (SQOR) inhibitor with an IC₅₀ of 30 nM. HTS07545 decrease the rate of breakdown of hydrogen sulfide (H2S). HTS07545 can be used for heart failure research .

HY-109582

ADT-OH 1 Publications Verification 5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione; ACS 1	Apoptosis	Cancer
ADT-OH is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD. ADT-OH has the potential for the research of cancer diseases .

HY-E70078

Cystathionine β-synthase	Biochemical Assay Reagents	Others
Cystathionine β-synthase is an enzyme that catalyzes the condensation of serine and homocysteine to water and cystathionine. Cystathionine β-synthase is a prominent enzyme for the production of hydrogen sulfide (H₂S) .

HY-160240

HPI

Others Others

HPI is a HS ^- fluorescent probe (Ex/Em=280/410 nm). HPI can be used to detect the HS ^- form of hydrogen sulfide (H₂S) gas in environmental water samples .

HPI	Others	Others
HPI is a HS ^- fluorescent probe (Ex/Em=280/410 nm). HPI can be used to detect the HS ^- form of hydrogen sulfide (H₂S) gas in environmental water samples .

HY-141552

FC9402	Others	Cardiovascular Disease
FC9402 is a potent and selective sulfide quinone oxidoreductase (SQOR) inhibitor extracted from patent WO 2020/146636 A1. FC9402 attenuates TAC-induced cardiomyocyte hypertrophy and left ventricle (LV) fibrosis. FC9402 can be used for cardiovascular regulation .

HY-120425

Ethiprole	Others	Infection
Ethiprole is an insecticide.Metabolic sulfones are produced faster than Fipronil (HY-B0822) in CYP3A4-expressing cells and in vivo in mouse brain and liver.Ethiprole's sulfide, sulfoxide, sulfone and desulfinyl derivatives have better biological activity .

HY-121955

FW1256 1 Publications Verification	NF-κB Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
FW1256 is a phenyl analogue and a slow-releasing hydrogen sulfide (H₂S) donor. FW1256 inhibits NF-κB activity and induces cell apoptosis. FW1256 exerts potent anti-inflammatory effects and has the potential for cancer and cardiovascular disease treatment .

HY-D1256

Msr-blue	Fluorescent Dye	Neurological Disease Metabolic Disease
Msr-blue is a first turn-on fluorescent probe for methionine sulfoxide reductase with a more than 100-fold fluorescence increment. Msr-blue is used for monitoring the enzyme activity in live cells (λex=340 nm, λem=440 nm) .

HY-134495

N-Acetyl-L-cysteine ethyl ester 3 Publications Verification N-Acetylcysteine ethyl ester; NACET	Reactive Oxygen Species	Metabolic Disease
N-Acetyl-L-cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC). N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H₂S) and can be used as an H₂S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant .

HY-106784A

(E)-Ajoene	Others	Neurological Disease
(E)-Ajoene is a oxygenated ajoene and organosulfur compound, which can be acquired via allicin decomposing. The polysulfides from garlic can be converted by human red blood cells into hydrogen sulfide (H2S) and allyl glutathione. (E)-Ajoene has been proved to show neuroprotective effects against ischemic damage. (E)-Ajoene is orally active to inhibit lipid peroxidation. (E)-Ajoene increases the number of cresyl violet-positive neurons and decreases the number of reactive gliosis in the CA1 region .

HY-112555

PDE7-IN-2	Phosphodiesterase (PDE)	Neurological Disease
PDE7-IN-2 (compound 2) is a potent PDE7 (phosphodiesterase 7) inhibitor with IC₅₀ value of 2.1 µM. PDE7-IN-2 has the potential for the research of parkinson’s disease .

HY-P1695

Cinnamycin

Ro 09-0198
Antibiotic Bacterial Infection

Cinnamycin (Ro 09-0198) is a tetracyclic peptide antibiotic that binds specifically to phosphatidylethanolamine (PE) .

Cinnamycin Ro 09-0198	Antibiotic Bacterial	Infection
Cinnamycin (Ro 09-0198) is a tetracyclic peptide antibiotic that binds specifically to phosphatidylethanolamine (PE) .

HY-P1726A

MSG606 TFA	Melanocortin Receptor
MSG606 TFA is a potent human MC1 receptor antagonist (IC₅₀=17 nM). MSG606 TFA also partial agonist at human MC3 and MC5 receptors (EC₅₀ values are 59 and 1300 nM, respectively). MSG606 TFA exhibits binding affinity for A375 melanoma cells in vitro. MSG606 TFA reverses the induced hyperalgesia in female mice, with no effect in male mice.

HY-P1726

MSG606

Melanocortin Receptor Neurological Disease

MSG606 is a selective MC1R (melanocortin 1 receptor) antagonist and can be used for the research of neuroprotective effects .

MSG606	Melanocortin Receptor	Neurological Disease
MSG606 is a selective MC1R (melanocortin 1 receptor) antagonist and can be used for the research of neuroprotective effects .

CAY10731	Fluorescent Dyes/Probes
CAY10731 (compound 3) is a highly selective fluorescent probe for detection of hydrogen sulfide (H₂S). CAY10731 is used to monitor exo- and endogenous H₂S in both cancer and normal cells. CAY10731 is applied for imaging of H₂S in living tissues at variable depths and in nematodes .

Msr-blue	Fluorescent Dyes/Probes
Msr-blue is a first turn-on fluorescent probe for methionine sulfoxide reductase with a more than 100-fold fluorescence increment. Msr-blue is used for monitoring the enzyme activity in live cells (λex=340 nm, λem=440 nm) .

Dibutyl sulfide	Biochemical Assay Reagents
Dibutyl sulfide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Hemoglobin	Native Proteins
Hemoglobin is a iron-containing protein in red blood cells with oxygen binding properties. Hemoglobin consits of heme, which binds to oxygen. Hemoglobin also transports other gases, such as carbon dioxide, nitric oxide, hydrogen sulfide and sulfide. Hemoglobin absorbs unneeded oxygen in tissues, as an antioxidant .

Cystathionine β-synthase	Biochemical Assay Reagents
Cystathionine β-synthase is an enzyme that catalyzes the condensation of serine and homocysteine to water and cystathionine. Cystathionine β-synthase is a prominent enzyme for the production of hydrogen sulfide (H₂S) .

Cat. No.	Product Name	Target	Research Area

HY-P4909

Autoinducing Peptide I

Peptides Infection

Autoinducing Peptide I is a cyclic octapeptide secreted by Staphylococcus aureus and can be used in vaccine research .
HY-P2031

Phallacidin

Arp2/3 Complex Others

Phallacidin is a member of the phallotoxin family of mushroom toxins. Phallacidin binds F-actin .
HY-P0028

Phalloidin

5+ Cited Publications

Fluorescent Dye Others

Phalloidin is a mushroom-derived toxin which can be used to label F-actin of the cytoskeleton with fluorochrome .
HY-P10014

Bibapcitide

Peptides Cardiovascular Disease

Bibapcitide, a 26 amino acid, inhibits thrombosis .

Autoinducing Peptide I	Peptides	Infection
Autoinducing Peptide I is a cyclic octapeptide secreted by Staphylococcus aureus and can be used in vaccine research .

Phallacidin	Arp2/3 Complex	Others
Phallacidin is a member of the phallotoxin family of mushroom toxins. Phallacidin binds F-actin .

Phalloidin 5+ Cited Publications	Fluorescent Dye	Others
Phalloidin is a mushroom-derived toxin which can be used to label F-actin of the cytoskeleton with fluorochrome .

HY-P3143

BMSpep-57	PD-1/PD-L1	Cancer
BMSpep-57 is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC₅₀ of 7.68 nM. BMSpep-57 binds to PD-L1 with K_ds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 facilitates T cell function by in creasing IL-2 production in PBMCs .

HY-P3143A

BMSpep-57 hydrochloride	PD-1/PD-L1	Cancer
BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC₅₀ of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with K_ds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs .

HY-P0041A

F992 TFA

Vasopressin Receptor Neurological Disease

F992 TFA is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .

HY-P1726A

MSG606 TFA	Melanocortin Receptor
MSG606 TFA is a potent human MC1 receptor antagonist (IC₅₀=17 nM). MSG606 TFA also partial agonist at human MC3 and MC5 receptors (EC₅₀ values are 59 and 1300 nM, respectively). MSG606 TFA exhibits binding affinity for A375 melanoma cells in vitro. MSG606 TFA reverses the induced hyperalgesia in female mice, with no effect in male mice.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-128447

Allyl methyl sulfide	Infection Structural Classification Natural Products Liliaceae Classification of Application Fields Source classification Plants Endogenous metabolite Disease Research Fields A．Sativam L. var．Viviparum Regel	Bacterial Endogenous Metabolite
Allyl methyl sulfide is a bioactive organosulfur compound found in garlic. Allyl methyl sulfide exhibits antibacterial, antioxidant and anticancer properties .

HY-P2031

Phallacidin	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Arp2/3 Complex
Phallacidin is a member of the phallotoxin family of mushroom toxins. Phallacidin binds F-actin .

HY-106784A

(E)-Ajoene	Structural Classification Natural Products Source classification Allium sativum L. Plants Amaryllidaceae	Others
(E)-Ajoene is a oxygenated ajoene and organosulfur compound, which can be acquired via allicin decomposing. The polysulfides from garlic can be converted by human red blood cells into hydrogen sulfide (H2S) and allyl glutathione. (E)-Ajoene has been proved to show neuroprotective effects against ischemic damage. (E)-Ajoene is orally active to inhibit lipid peroxidation. (E)-Ajoene increases the number of cresyl violet-positive neurons and decreases the number of reactive gliosis in the CA1 region .

Cat. No.	Product Name	Chemical Structure

HY-W013186S

*Lansoprazole sulfide-d4*
Lansoprazole sulfide-d₄ is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 µM intracellularly and 0.46 µM in broth[1].

HY-141776S

*Omeprazole sulfide-d3*
Omeprazole sulfide-d₃ is the deuterium labeled Omeprazole sulfide. Omeprazole metabolite Omeprazole sulfide (Ufiprazole) is a metabolite of Omeprazole, which is a proton pump inhibitor.

HY-B1786S

*Sulindac sulfide-d3*
Sulindac sulfide-d₃ is deuterium labeled Sulindac sulfide. Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.

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Sulfide

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Click Chemistry

Natural
Products