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Results for "

Sulfonylurea

" in MedChemExpress (MCE) Product Catalog:

44

Inhibitors & Agonists

2

Peptides

2

Natural
Products

1

Recombinant Proteins

10

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W020020
    Thifensulfuron-methyl

    		Others Others
    Thifensulfuron-methyl is a sulfonylurea herbicide and mainly used for control of broadleaved weeds in wheat, corn, and soybean fields .
    Thifensulfuron-methyl
  • HY-121079
    Azimsulfuron

    DPX-A8947

    		 Others Others
    Azimsulfuron (DPX-A8947) is a sulfonylurea herbicide useful in controlling weeds in paddy fields .
    Azimsulfuron
  • HY-W011651
    Carbutamide

    BZ-55

    		 Others Metabolic Disease
    Carbutamide (BZ-55) is an orally active and first-generation sulfonylurea with hypoglycemic activity .
    Carbutamide
  • HY-115962
    Anticancer agent 37

    		Others Cancer
    Anticancer agent 37 (compound 18), a sulfonylurea derivative, is a potent anticancer agent. Anticancer agent 37 inhibits HePG2 cell growth with an IC50 of 17.2 µg/mL .
    Anticancer agent 37
  • HY-115963
    Anticancer agent 38

    		Others Cancer
    Anticancer agent 38 (compound 19), a sulfonylurea derivative, is a potent anticancer agent. Anticancer agent 38 inhibits A431 cell growth with an IC50 of 5.2 µg/mL .
    Anticancer agent 38
  • HY-137245
    Emlenoflast

    MCC7840

    		 NOD-like Receptor (NLR) Inflammation/Immunology
    Emlenoflast (MCC7840), a sulfonylurea, is a potent and selective inhibitor of NLRP3 inflammasome, with an IC50 of <100 nM. Emlenoflast can be used for the research of inflammatory diseases .
    Emlenoflast
  • HY-137245A
    Emlenoflast sodium

    MCC7840 sodium

    		 NOD-like Receptor (NLR) Inflammation/Immunology
    Emlenoflast (MCC7840) sodium, a sulfonylurea, is a potent and selective inhibitor of NLRP3 inflammasome, with an IC50 of <100 nM. Emlenoflast sodium can be used for the research of inflammatory diseases .
    Emlenoflast sodium
  • HY-B1876
    Nicosulfuron

    		Acetolactate Synthase (ALS) Others
    Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity .
    Nicosulfuron
  • HY-115960
    Anticancer agent 35

    		Others Cancer
    Anticancer agent 35 (compound 10), a sulfonylurea derivative, is a potent anticancer agent. Anticancer agent 35 inhibits A549, A431, PACA2 cell growth with IC50s of 18.1 µg/mL, 4.0 µg/mL, 18.9 µg/mL, respectively .
    Anticancer agent 35
  • HY-B0254
    Glipizide

    CP 28720; K 4024

    		 Potassium Channel Metabolic Disease
    Glipizide (CP 2872; K 4024) a potent, orally active and sulfonylurea class anti-diabetic agent and can be used for type 2 diabetes mellitus research but not type 1. Glipizide acts by partially blocking ATP-sensitive potassium (KATP) channels among β cells of pancreatic islets of Langerhans .
    Glipizide
  • HY-115959
    Anticancer agent 34

    		Bacterial Inflammation/Immunology Cancer
    Anticancer agent 34 (compound 9), a sulfonylurea derivative, is a potent antimicrobial and anticancer agent. Anticancer agent 34 inhibits the microbial growth of B. mycoides, E. coli, and C. albicans with a MIC between 0.156 and 0.039 mg/ml. Anticancer agent 34 inhibits A549, PC3 cell growth with IC50s of 8.4 µg/ml, 7.8 µg/ml, respectively .
    Anticancer agent 34
  • HY-115961
    Anticancer agent 36

    		Bacterial Inflammation/Immunology Cancer
    Anticancer agent 36 (compound 11), a sulfonylurea derivative, is a potent antimicrobial and anticancer agent. Anticancer agent 36 inhibits the microbial growth of B. mycoides, E. coli, and C. albicans with a MIC between 0.156 and 0.039 mg/L. Anticancer agent 36 inhibits A549, PC3 cell growth with IC50s of 19.7 µg/mL, 11.9 µg/mL, respectively .
    Anticancer agent 36
  • HY-136357
    Tribenuron

    		Others Others
    Tribenuron, a slow acting sulfonylurea herbicide, controls broadleaf weed .
    Tribenuron
  • HY-B0104
    Glimepiride
    3 Publications Verification

    Glimperide; HOE-490

    		 Amyloid-β Metabolic Disease
    Glimepiride (Glimperide) is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg.
    Glimepiride
  • HY-B0870
    Bensulfuron-methyl

    Bensulfuron-methyl is a kind of sulfonylurea herbicide widely used to control broad-leaf weeds in rice paddies .
    Bensulfuron-methyl
  • HY-15383
    Glyparamide

    		Others Others
    Glyparamide is an orally active chlorophenyl-containing sulfonylurea. Glyparamide shows hypoglycemic activity and rarely causes hepatic injury .
    Glyparamide
  • HY-B0881
    Acetohexamide

    		Others Metabolic Disease Cancer
    Acetohexamide is a first-generation sulfonylurea medication used to treat diabetes mellitus type 2; stimulate the pancreas to secrete insulin.
    Acetohexamide
  • HY-B1114
    Gliquidone

    AR-DF 26

    		 Others Metabolic Disease
    Gliquidone (AR-DF 26) is an anti-diabetic agent in the sulfonylurea class, used in the treatment of diabetes mellitus type 2.
    Gliquidone
  • HY-B0401S
    Tolbutamide-d9

    		Potassium Channel Autophagy Metabolic Disease Cancer
    Tolbutamide-d9 is the deuterium labeled Tolbutamide. Tolbutamide is a first generation potassium channel blocker, sulfonylurea oral hypoglycemic agent.
    Tolbutamide-d9
  • HY-B0401S1
    Tolbutamide-13C

    		Isotope-Labeled Compounds Potassium Channel Autophagy Metabolic Disease Cancer
    Tolbutamide- 13C is the 13C-labeled Tolbutamide. Tolbutamide is a first generation potassium channel blocker, sulfonylurea oral hypoglycemic agent.
    Tolbutamide-13C
  • HY-133085
    Rimsulfuron

    DPX-E9636

    		 Others Others
    Rimsulfuron (DPX-E9636) is a sulfonylurea herbicide for postemergence use in maize to control grasses and some broadleaf weeds .
    Rimsulfuron
  • HY-B0104S
    Glimepiride-d5

    		Amyloid-β Isotope-Labeled Compounds Metabolic Disease
    Glimepiride-d5 is the deuterium labeled Glimepiride. Glimepiride (Glimperide) is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg.
    Glimepiride-d5
  • HY-P5290
    HYNIC-PSMA

    		PSMA Cancer
    HYNIC-PSMA is a ligand for molecular imaging of tumors. Hynic-psma consists of two components: HYNIC (6-hydrazinonicotinamide) and PSMA (Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules, such as 188Re-HYNIC-PSMA. PSMA is a membrane antigen that is specifically expressed on the surface of prostate cancer cells. HYNIC-PSMA can be used in prostate cancer research .
    HYNIC-PSMA
  • HY-P5292
    HYNIC-iPSMA

    		PSMA Cancer
    HYNIC-iPSMA is a ligand for molecular imaging of tumors. Hynic-ipsma consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules. iPSMA is a specific inhibitor used to inhibit prostate-specific membrane antigen (PSMA). 68GA-labeled iPSMA has been used to detect prostate cancer by PET imaging. The further 99mTc-EDDA/HYNIC-iPSMA has excellent specificity and sensitivity .
    HYNIC-iPSMA
  • HY-B0104S1
    Glimepiride-d4-1

    Glimperide-d4; HOE-490-d4

    		 Amyloid-β Isotope-Labeled Compounds Metabolic Disease
    Glimepiride-d4-1 is deuterium labeled Glimepiride. Glimepiride (Glimperide) is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg.
    Glimepiride-d4-1
  • HY-111912
    Tribenuron-methyl

    		Fungal Infection
    Tribenuron-methyl, a sulfonylurea herbicide agent, can be used as the fungicide agent. Tribenuron-methyl plays an important role in controlling the weeds and diseases in wheat field .
    Tribenuron-methyl
  • HY-B1114S
    Gliquidone-d6

    AR-DF 26-d6

    		 Isotope-Labeled Compounds Metabolic Disease
    Gliquidone-d6 is deuterium labeled Gliquidone. Gliquidone (AR-DF 26) is an anti-diabetic agent in the sulfonylurea class, used in the treatment of diabetes mellitus type 2.
    Gliquidone-d6
  • HY-133085S
    Rimsulfuron-d6

    DPX-E9636-d6

    		 Isotope-Labeled Compounds Others
    Rimsulfuron-d6 is deuterium labeled Rimsulfuron. Rimsulfuron (DPX-E9636) is a sulfonylurea herbicide for postemergence use in maize to control grasses and some broadleaf weeds[1][2].
    Rimsulfuron-d6
  • HY-B0089
    Acarbose
    3 Publications Verification

    BAY g 5421

    		 Glucosidase Metabolic Disease
    Acarbose (BAY g 5421), antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose can potentiate the hypoglycemic effects of sulfonylureas or insulin .
    Acarbose
  • HY-133085R
    Rimsulfuron (Standard)

    DPX-E9636 (Standard)

    		 Others Others
    Rimsulfuron (Standard) is the analytical standard of Rimsulfuron. This product is intended for research and analytical applications. Rimsulfuron (DPX-E9636) is a sulfonylurea herbicide for postemergence use in maize to control grasses and some broadleaf weeds .
    Rimsulfuron (Standard)
  • HY-B0089A
    Acarbose sulfate

    Bay-g 5421 sulfate

    		 Glucosidase Metabolic Disease
    Acarbose (BAY g 5421) sulfate, antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose sulfate can potentiate the hypoglycemic effects of sulfonylureas or insulin .
    Acarbose sulfate
  • HY-100641
    4-Hydroxytolbutamide

    Hydroxytolbutamide
    4-Hydroxytolbutamide (Hydroxytolbutamide) is a metabolite of Tolbutamide. 4-Hydroxytolbutamide is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium channel blocker and a sulfonylurea oral antidiabetic .
    4-Hydroxytolbutamide
  • HY-B1869
    Metsulfuron-methyl

    Metsulfuron-methyl is a systemic sulfonylurea herbicide and has been widely used to control broad-leaved weeds and annual grasses in rice, maize, wheat, and barley. Metsulfuron-methyl has highly efficient herbicidal activity and low mammalian toxicity .
    Metsulfuron-methyl
  • HY-B0870S
    Bensulfuron-methyl-d6

    		Isotope-Labeled Compounds Others
    Bensulfuron-methyl-d6 is a deuterated Bensulfuron-methyl (HY-B0870) (sulfonylurea pesticides). Bensulfuron-methyl-d6 can be used as an internal standard for the determination of pesticide residues by LC-MS[1].
    Bensulfuron-methyl-d6
  • HY-124150
    BM567

    		Prostaglandin Receptor Cardiovascular Disease
    BM567 is a sulfonylurea compound (compound 1), which exhibits antithrombogenic efficacy as thromboxane A2 receptor (TXR) antagonists and thromboxane A2 synthase (TXS) inhibitors, with IC50s of 1.1 and 12 nM, respectively .
    BM567
  • HY-W422402
    Foramsulfuron

    		Acetolactate Synthase (ALS) Others
    Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.). Foramsulfuron is a sulfonylurea herbicide that exerts its herbicidal activity by inhibiting acetolactate synthase (ALS), a key enzyme in the biosynthesis of branched chain amino acids .
    Foramsulfuron
  • HY-B1876S
    Nicosulfuron-d6

    		Acetolactate Synthase (ALS) Others
    Nicosulfuron-d6 is the deuterium labeled Nicosulfuron[1]. Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity[2].
    Nicosulfuron-d6
  • HY-B1876R
    Nicosulfuron (Standard)

    		Acetolactate Synthase (ALS) Others
    Nicosulfuron (Standard) is the analytical standard of Nicosulfuron. This product is intended for research and analytical applications. Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity .
    Nicosulfuron (Standard)
  • HY-118742
    Benzobicyclon

    		HPPD Others
    Benzobicyclon is a 4-HPPD inhibitor and herbicide that reacts with water to form a hydrolysate of the active herbicide benzobicycline, causing bleaching and death of weeds. Benzobicyclon is effective against grass, sedge and broadleaf weeds. Benzobicyclon effectively targets sulfonylurea herbicide-resistant biotypes as well as wild-type weeds .
    Benzobicyclon
  • HY-100641S
    4-Hydroxytolbutamide-d9

    Hydroxytolbutamide-d9

    		 Potassium Channel Autophagy Metabolic Disease Cancer
    4-Hydroxytolbutamide-d9 is the deuterium labeled 4-Hydroxytolbutamide. 4-Hydroxytolbutamide (Hydroxytolbutamide) is a metabolite of Tolbutamide. 4-Hydroxytolbutamide is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium channel blocker and a sulfonylurea oral antidiabetic[1][2].
    4-Hydroxytolbutamide-d9
  • HY-B0254S
    Glipizide-d11

    		Potassium Channel Metabolic Disease
    Glipizide-d11 is the deuterium labeled Glipizide. Glipizide (CP 2872; K 4024) a potent, orally active and sulfonylurea class anti-diabetic agent and can be used for type 2 diabetes mellitus research but not type 1. Glipizide acts by partially blocking ATP-sensitive potassium (KATP) channels among β cells of pancreatic islets of Langerhans[1][2].
    Glipizide-d11
  • HY-108573
    P-1075
    1 Publications Verification

    		 Potassium Channel Cardiovascular Disease
    P-1075 is a potent activator of sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-KIR6), with an EC50 value of 45 nM for SUR2B-KIR6 channel activation . P-1075 also P1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts .
    P-1075
  • HY-153261
    NLRP3-IN-17

    		NOD-like Receptor (NLR) Inflammation/Immunology
    NLRP3-IN-17 is a potent, selective and orally active NLRP3 inflammasome inhibitor with an IC50 value of 7 nM. NLRP3-IN-17 significantly inhibits NLRP3 dependent IL-1β secretion in mice and can be used for chronic inflammatory diseases research .
    NLRP3-IN-17
  • HY-155517
    INF200

    		NOD-like Receptor (NLR) Pyroptosis Inflammation/Immunology
    INF200 (compound 5) is a sulfonylurea-based inhibitor of NLRP3 and NLRP3-mediated pyroptosis. INF200 has beneficial cardiometabolic effects in rat model of high-fat diet (HFD)-induced metaflammation，and shows anti-inflammatory activity to (10 μM) decreases IL-1β release in human macrophages. INF200 improves glucose and lipid profiles，and attenuates systemic inflammation and biomarkers of cardiac dysfunction (particularly BNP). INF200 also improves myocardial damage-dependent ischemia/reperfusion injury (IRI) in hemodynamic evaluation .
    INF200

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