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TNFRSF11A

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P72483
    RANK/TNFRSF11A Protein, Mouse (HEK293, His)

    Tumor necrosis factor receptor superfamily member 11A; ODFR; CD265; TNFRSF11A; Rank

    		 Mouse HEK293
    RANK (TNFRSF11A) is a receptor activator of nuclear factor κB (NF-κB), which is involved in bone metabolism and immune system function. RANK is mainly expressed by osteoblasts/stromal cells, and is associated with the formation of giant cell tumor of bone (GCTBs) . RANK combined with RANKL ligand activated the RANKL/RANK/ OPG system to regulate bone resorption . RANKL/RANK is also a regulator of dendritic cell (DC)-T cell interaction, which is associated with mammary epithelial formation and central nervous system thermoregulation in lactating female . RANK/TNFRSF11A Protein, Mouse (HEK293, His) has 184 amino acids (V31-S214), produced by HEK293 cells with C-terminal 6*His-tag.

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