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Results for "

TNIK-IN-4

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-111754
    DMX-5804
    1 Publications Verification

    		 MAP4K Cardiovascular Disease
    DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor, with an IC50 of 3 nM, a pIC50 of 8.55 for human MAP4K4, less potent on MINK1/MAP4K6 (pIC50, 8.18), and TNIK/MAP4K7 (pIC50, 7.96). DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice .
    DMX-5804
  • HY-143436
    TNIK-IN-4

    		Others Cancer
    TNIK-IN-4 is a potent TNIK inhibitor with IC50 of 0.61 μM. TNIK-IN-4 has inhibitory activity against typical colorectal cancer cell line HCT116 .
    <em>TNIK-IN-4</em>
  • HY-156523
    TNIK&MAP4K4-IN-1

    		MAP4K Cancer
    TNIK&MAP4K4-IN-1 (compound A-39) is a dual inhibitor of TNIK and MAP4K4/HGK with IC50s of 1.29 nM and <10 nM，respectively，in human hepaticstellate cell LX-2. TNIK&MAP4K4-IN-1 can be used for cancer and fibrosis inhibition .
    <em>TNIK&MAP4</em>K<em>4</em>-IN-1
  • HY-160623
    TNIK&MAP4K4-IN-2

    		MAP4K Cancer
    TNIK&MAP4K4-IN-2 (compound 112) is a TNIK and MAP4K4 inhibitor with IC50 values of 12-120, 12-120 nM, respectively .
    <em>TNIK&MAP4</em>K<em>4</em>-IN-2

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