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Results for "

TR��

" in MCE Product Catalog:

By Targets:	ADC Linker (5) Antibiotic (4) Bacterial (4) Drug Metabolite (1) Endogenous Metabolite (4) Epigenetic Reader Domain (4) Fluorescent Dye (9) FXR (1) Glucocorticoid Receptor (1) Histone Acetyltransferase (4) Histone Demethylase (1) Influenza Virus (2) Integrin (1) Keap1-Nrf2 (1) NF-κB (2) Parasite (1) PPAR (1) PROTAC Linkers (5) Thyroid Hormone Receptor (15)
By Research Areas:	Cancer (20) Cardiovascular Disease (3) Endocrinology (11) Infection (8) Inflammation/Immunology (14) Metabolic Disease (7)

Inhibitors & Agonists

Fluorescent Dye

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas

HY-U00274

Ropitoin
TR 2985
Others Cardiovascular Disease

Ropitoin (TR 2985) is a novel antiarrhythmic drug.

Ropitoin TR 2985	Others	Cardiovascular Disease
Ropitoin (TR 2985) is a novel antiarrhythmic drug.

HY-110212

BODIPY TR-X BODIPY TR-X NHS Ester	Fluorescent Dye	Others
BODIPY TR-X (BODIPY TR-X NHS Ester) is a potent fluorescent dye. BODIPY TR-X can be used to label the primary amines (R-NH₂) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. BODIPY TR-X binds to protein or antibody and has bright, red fluorescent light. (λ_ex=545 nm, λ_em=560 nm).

HY-111443

TR antagonist 1	Thyroid Hormone Receptor	Metabolic Disease Endocrinology
TR antagonist 1 is a high-affinity thyroid hormone receptor (TR) antagonist with IC₅₀s of 36 and 22 nM for TRα and TRβ, respectively.

HY-15770

TR-14035	Integrin	Inflammation/Immunology
TR-14035 is a orally active dual α₄β₇/α₄β₁ integrin antagonist, with IC₅₀ s of 7 nM and 87 nM for α₄β₇ and α₄β₁, respectively. TR-14035 can be used for the research of inflammation and autoimmune diseases.

HY-14855B

Tedizolid phosphate
TR-701FA
Bacterial Antibiotic Infection

Tedizolid phosphate (TR-701FA) is a novel oxazolidinone with activity against Gram-positive pathogens.

Tedizolid phosphate TR-701FA	Bacterial Antibiotic	Infection
Tedizolid phosphate (TR-701FA) is a novel oxazolidinone with activity against Gram-positive pathogens.

HY-151775

BDP TR azide	Fluorescent Dye	Others
BDP TR azide is a click chemistry reagent containing an azide group that can react with alkynes, DBCO and BCN. BDP TR azide is also a fluorescent dye that can be used in fluorescence polarization assays and microscopy.

HY-D1646

BDP TR methyltetrazine
Fluorescent Dye Others

BDP TR methyltetrazine is a BDP dye linker containing a methyltetrazine group.

BDP TR methyltetrazine	Fluorescent Dye	Others
BDP TR methyltetrazine is a BDP dye linker containing a methyltetrazine group.

HY-D1585

BODIPY TR methyl ester	Fluorescent Dye	Others
BODIPY TR methyl ester is a lipophilic GFP Counterstain. BODIPY TR methyl ester dye readily permeates cell membranes and localizes in endomembranous organelles but not localize strongly in plasma membranes. BODIPY TR methyl ester is an excellent red fluorescent vital dye (Ex=568 nm, Em=625 nm), can be used to reveal the location and shapes of cell nuclei, the shapes of cells within embryonic tissues, as well as the bound aries of organ-forming tissues within the whole embryo.

HY-D1594

BODIPY TR Cadaverine	Fluorescent Dye	Others
BODIPY TR Cadaverine, a cadaverine derivative, is a red fluorescent dye. BODIPY TR Cadaverine can be used in a a highly sensitive and robust fluorescent displacement assay, which binds to native LPS strongly, specifically recognizing lipid A, and is competitively displaced by compounds displaying an affinity for lipid A.

HY-130165

Tr-PEG8-OH	ADC Linker PROTAC Linkers	Cancer Inflammation/Immunology
Tr-PEG8-OH is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tr-PEG8-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-120845

Tr-PEG5-OH	ADC Linker PROTAC Linkers	Cancer Inflammation/Immunology
Tr-PEG5-OH is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tr-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-114995

Tr-PEG2-OH	PROTAC Linkers ADC Linker	Cancer Inflammation/Immunology
Tr-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Tr-PEG2-OH is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-14855

Tedizolid TR 700; Torezolid; DA-7157	Bacterial Antibiotic	Infection
Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.

HY-D1490

Fast red TR salt hemi(zinc chloride)
Fluorescent Dye Others

Fast red TR salt hemi (zinc chloride) is a diazonium dye with red color.
HY-126883

Tr-PEG4-OH
PROTAC Linkers Cancer Inflammation/Immunology

Tr-PEG4-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129311

Tr-PEG6-OH
ADC Linker Cancer Inflammation/Immunology

Tr-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-120258

Tr-PEG3-OH
ADC Linker Cancer Inflammation/Immunology

Tr-PEG3-OH is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Fast red TR salt hemi(zinc chloride)	Fluorescent Dye	Others
Fast red TR salt hemi (zinc chloride) is a diazonium dye with red color.

Tr-PEG4-OH	PROTAC Linkers	Cancer Inflammation/Immunology
Tr-PEG4-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Tr-PEG6-OH	ADC Linker	Cancer Inflammation/Immunology
Tr-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Tr-PEG3-OH	ADC Linker	Cancer Inflammation/Immunology
Tr-PEG3-OH is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-129150

Ganoderic acid TR	Influenza Virus	Infection
Ganoderic acid TR is a broad-spectrum inhibitor against influenza neuraminidases (NAs), particularly H5N1 and H1N1 neuraminidases. The IC₅₀ values of 10.9 and 4.6 μM, respectively.

HY-141229

Methoxy-Tr-NH-PEG7
PROTAC Linkers Cancer

Methoxy-Tr-NH-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Methoxy-Tr-NH-PEG7	PROTAC Linkers	Cancer
Methoxy-Tr-NH-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-N0510

Aristolochic acid A Aristolochic acid I; TR 1736	NF-κB	Cancer
Aristolochic acid A (Aristolochic acid I; TR 1736) is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines.

HY-D1735

BODIPY TR Ceramide
Golgi-Red Tracke
Fluorescent Dye Others

BODIPY TR Ceramide (Golgi-Red Tracke) is a red-fluorescent probe of the Golgi apparatus in live cells (Ex=589 nm, Em=616 nm).

BODIPY TR Ceramide Golgi-Red Tracke	Fluorescent Dye	Others
BODIPY TR Ceramide (Golgi-Red Tracke) is a red-fluorescent probe of the Golgi apparatus in live cells (Ex=589 nm, Em=616 nm).

HY-W414380

Bdp tr nhs ester	Fluorescent Dye	Others
Bdp tr nhs ester is a chemiluminescent coupling compound with a long excited state lifetime for immunoassays and is suitable for microscopy and fluorescence polarization analysis applications. NHS ester can react specifically and efficiently with the side chains of primary amines such as lysine residues or amino silane coated surfaces under neutral or weakly basic conditions to form covalent bonds.

HY-147501

TRβ agonist 3	Thyroid Hormone Receptor	Metabolic Disease
TRβ agonist 3 (Compound 3) is a potent agonist of TRβ. TRβ agonist 3 reduces lipid accumulation in HepG2 and promote lipolysis with comparable effects. TRβ agonist 3 is a new potential TRβ-selective thyromimetics.

HY-147500

TRβ agonist 2	Thyroid Hormone Receptor	Metabolic Disease
TRβ agonist 2 (Compound 1) is a potent agonist of TRβ. TRβ agonist 2 reduces lipid accumulation in HepG2 and promote lipolysis with comparable effects. TRβ agonist 2 is a new potential TRβ-selective thyromimetics.

HY-14855S

Tedizolid-13C,d3 TR 700-¹³C,d₃; Torezolid-¹³C,d₃; DA-7157-¹³C,d₃	Bacterial Antibiotic	Infection
Tedizolid-¹³C,d₃ is the ¹³C- and deuterium labeled Tedizolid. Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.

HY-146997

TRβ agonist 1	Thyroid Hormone Receptor	Metabolic Disease
TRβ agonist 1 is a selective and mutation-sensitive thyroid hormone receptor β (TRβ) agonist, with an EC₅₀ value of 21 nM. TRβ agonist 1 can be used for researching dyslipidemia, nonalcoholic steatohepatitis (NASH), and resistance to thyroid hormone (RTH).

HY-126236

3,5-Diiodothyropropionic acid	Thyroid Hormone Receptor	Cardiovascular Disease Endocrinology
3,5-Diiodothyropropionic acid is a thyroid hormone analog, induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (TR), with K_a of 2.40 and 4.06 M^-1 for TRα1 and TRβ1, respectively.

HY-12753A

Debutyldronedarone hydrochloride SR35021 hydrochloride	Thyroid Hormone Receptor	Cardiovascular Disease
Debutyldronedarone (SR35021) hydrochloride, the main metabolite of Dronedarone, is a selective thyroid hormone receptor α₁ (TRα₁) inhibitor. Debutyldronedarone hydrochloride inhibits T3 binding to TRα₁ and TRβ₁ by 77% and 25%, respectively. Debutyldronedarone hydrochloride can be used for the research of arrhythmic.

HY-10473

Eprotirome KB2115	Thyroid Hormone Receptor	Endocrinology Metabolic Disease
Eprotirome (KB2115) is a liver-selective thyroid hormone receptor (TR) agonist. KB2115 has modestly higher affinity for TRβ than for TRα. Eprotirome reduces low-density lipoprotein (LDL) cholesterol concentrations. Eprotirome can be used for dyslipidemias and obesity research.

HY-A0070B

Liothyronine sodium hydrate Triiodothyronine sodium hydrate; 3,3',5-Triiodo-L-thyronine sodium hydrate; T3 sodium hydrate	Thyroid Hormone Receptor Endogenous Metabolite	Cancer Endocrinology
Liothyronine sodium hydrate is an active form of thyroid hormone. Liothyronine sodium hydrate is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively.

HY-A0070

Liothyronine sodium Triiodothyronine sodium; 3,3',5-Triiodo-L-thyronine sodium; T3 sodium	Thyroid Hormone Receptor Endogenous Metabolite	Cancer Endocrinology
Liothyronine sodium is an active form of thyroid hormone. Liothyronine sodium is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively.

HY-A0070C

Liothyronine hydrochloride Triiodothyronine hydrochloride; 3,3',5-Triiodo-L-thyronine hydrochloride; T3 hydrochloride	Thyroid Hormone Receptor Endogenous Metabolite	Cancer Endocrinology
Liothyronine hydrochloride is an active form of thyroid hormone. Liothyronine hydrochloride is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively.

HY-A0070A

Liothyronine Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3	Thyroid Hormone Receptor Endogenous Metabolite	Cancer Endocrinology
Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively.

HY-14823

Sobetirome GC-1; QRX-431	Thyroid Hormone Receptor	Metabolic Disease Endocrinology
Sobetirome (GC-1) is a thyroid hormone receptor β (TRβ)-specific agonist which bind selectively to TRβ-1 with an EC₅₀ of 0.16 μM.

HY-A0070AS2

Liothyronine-13C6-1 Triiodothyronine-13C6-1; 3,3',5-Triiodo-L-thyronine-13C6-1; T3-13C6-1	Thyroid Hormone Receptor	Cancer Endocrinology
Liothyronine-13C6-1 is a 13C-labeled Liothyronine. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively.

HY-N2264

Wulignan A1	Influenza Virus	Infection
Wulignan A1 is isolated from the stems of Schisandra henryi. Wulignan A1 exhibits anti-influenza virus H1N1 and *H1N1-TR* (a Tamiflu drug resistant virus strain) activities.

HY-14855A

(S)-Tedizolid (S)-TR 700; (S)-DA 7157	Bacterial Antibiotic	Infection
(S)-Tedizolid is the S-enantiomer of Tedizolid. Tedizolid is a novel oxazolidinone with activity against Gram-positive pathogens. (S)-Tedizolid is the less active isomer.

HY-A0070AG

Liothyronine Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3	Thyroid Hormone Receptor	Cancer Endocrinology
Liothyronine (Triiodothyronine) (GMP) is Liothyronine (HY-A0070A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively.

HY-145991

Ribavirin carboxylic acid
Drug Metabolite Infection

Ribavirin carboxylic acid (TR-COOH) is a metabolite of Ribavirin (HY-B0434), Ribavirin has strong antiviral activity.

Ribavirin carboxylic acid	Drug Metabolite	Infection
Ribavirin carboxylic acid (TR-COOH) is a metabolite of Ribavirin (HY-B0434), Ribavirin has strong antiviral activity.

HY-130012

CO23	Thyroid Hormone Receptor	Metabolic Disease Endocrinology
CO23 is a selective thyroid hormone receptor (TR) α agonist and used for growth and development regulation. CO23 was able to be transported through the blood-brain barrier.

HY-101027

GSK 4027	Epigenetic Reader Domain Histone Acetyltransferase	Cancer Inflammation/Immunology
GSK 4027 is a chemical probe for the PCAF/GCN5 bromodomain with an pIC₅₀ of 7.4±0.11 for PCAF in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay.

HY-101027A

GSK4028	Epigenetic Reader Domain Histone Acetyltransferase	Cancer Inflammation/Immunology
GSK4028 is the enantiomeric negative control of GSK4027, which is a PCAF/GCN5 bromodomain chemical probe, the pIC₅₀ of GSK4028 is 4.9 in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay.

HY-108435

GNE-049	Epigenetic Reader Domain Histone Acetyltransferase	Cancer
GNE-049 is a highly potent and selective CBP inhibitor with an IC₅₀ of 1.1 nM in TR-FRET assay. GNE-049 also inhibits BRET and BRD4(1) with IC₅₀s of 12 nM and 4200 nM, respectively.

HY-113827

THPN	Others	Inflammation/Immunology
THPN is a potent Nur77 agonist. THPN specifically binds the LBD of Nur77 (TR3) but not that of retinoic acid receptor α and PPARγ with a K_d of 270 nM. THPN leads to Nur77 translocation to the mitochondria to induce autophagic cell death in melanoma.

HY-139561

KDM2B-IN-2	Histone Demethylase	Cancer Inflammation/Immunology
KDM2B-IN-2, a potent histone demethylase (kdm2b) inhibitor with an IC₅₀ of 0.021 μM in a KDM2B TR-FRET assay. KDM2B-IN-2 can be used for hyperproliferative diseases research.

HY-W052512

Antitrypanosomal agent 1	Parasite	Infection
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor with an IC₅₀ of 3.3 μM. Antitrypanosomal agent 1 inhibits glutathione reductase (GR) (IC₅₀=64.8 μM) and T. brucei (EC₅₀=1 μM). Antitrypanosomal agent 1 has anti-trypanosomal activity.

HY-108696

GNE-781	Epigenetic Reader Domain Histone Acetyltransferase	Cancer
GNE-781 is an orally active, highly potent and selective CBP inhibitor with an IC₅₀ of 0.94 nM in TR-FRET assay. GNE-781 also inhibits BRET and BRD4(1) with IC₅₀s of 6.2 nM and 5100 nM, respectively. GNE-781 displays antitumor activity in an MOLM-16 AML xenograft model.

HY-110211

BODIPY TMR-X SE	Fluorescent Dye	Others
BODIPY TMR-X SE is a potent fluorescent dye. BODIPY TMR-X SE can be used to label the primary amines (R-NH₂) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. BODIPY TR-X binds to protein or antibody and has bright, orange fluorescent light. (λ_ex=544 nm, λ_em=570 nm).

HY-153114

HEC96719	FXR	Inflammation/Immunology
HEC96719 is a selective and orally active tricyclic farnesoid X receptor (FXR) agonist with EC₅₀ values of 1.37 and 1.55 nM by time-resolved fluorescence energy transfer (TR-FRET) and luciferase reporter assays, respectively. HEC96719 significantly improves non-alcoholic steatohepatitis (NASH) and liver fibrosis with favorable tissue distribution in liver and intestine. HEC96719 can be used for the research of non-alcoholic steatohepatitis.

HY-146561

S-HP210	Glucocorticoid Receptor NF-κB	Inflammation/Immunology
S-HP210 is a potent and selective glucocorticoid receptor (GR) with an IC₅₀ value of 1.92 μM for NF-κB transrepression (TR). S-HP210 represses the LPS-induced transcription of a variety of proinflammatory genes such as IL-1β, IL-6 and COX-2. S-HP210 is nontoxic at effective doses against mouse fibroblasts 3T3 cells.

HY-114263

NXT629	PPAR	Cancer
NXT629 is a potent, selective, and competitive PPAR-α antagonist, with an IC₅₀ of 77 nM for human PPARα, shows high selectivity over other nuclear hormone receptor, such as PPARδ, PPARγ, ERβ, GR and TRβ, IC₅₀s are 6.0, 15, 15.2, 32.5 and >100 μM, respectively. NXT629 has potent anti-tumor activity and inhibits experimental metastasis of cancer cell in animal models.

HY-146578

Keap1-Nrf2-IN-8	Keap1-Nrf2	Inflammation/Immunology
Keap1-Nrf2-IN-8 (compound 12d) is a potent Keap1-Nrf2 PPI (Keap1-Nrf2 protein−protein interaction) inhibitor with IC₅₀s of 64.5 nM and 14.2 nM for FP and TR-FRET assays, respectively. Keap1-Nrf2-IN-8 significantly increases the mRNA levels of Nrf2 downstream genes, GSTM3, HMOX2 and NQO1.

Cat. No.	Product Name	Type

HY-110212

BODIPY TR-X BODIPY TR-X NHS Ester	Protein Labeling
BODIPY TR-X (BODIPY TR-X NHS Ester) is a potent fluorescent dye. BODIPY TR-X can be used to label the primary amines (R-NH₂) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. BODIPY TR-X binds to protein or antibody and has bright, red fluorescent light. (λ_ex=545 nm, λ_em=560 nm).

HY-151775

BDP TR azide	Fluorescent Dyes/Probes
BDP TR azide is a click chemistry reagent containing an azide group that can react with alkynes, DBCO and BCN. BDP TR azide is also a fluorescent dye that can be used in fluorescence polarization assays and microscopy.

HY-D1646

BDP TR methyltetrazine
Fluorescent Dyes/Probes

BDP TR methyltetrazine is a BDP dye linker containing a methyltetrazine group.

HY-D1585

BODIPY TR methyl ester

Fluorescent Dyes/Probes

BODIPY TR methyl ester is a lipophilic GFP Counterstain. BODIPY TR methyl ester dye readily permeates cell membranes and localizes in endomembranous organelles but not localize strongly in plasma membranes. BODIPY TR methyl ester is an excellent red fluorescent vital dye (Ex=568 nm, Em=625 nm), can be used to reveal the location and shapes of cell nuclei, the shapes of cells within embryonic tissues, as well as the bound aries of organ-forming tissues within the whole embryo.

HY-D1594

BODIPY TR Cadaverine	Fluorescent Dyes/Probes
BODIPY TR Cadaverine, a cadaverine derivative, is a red fluorescent dye. BODIPY TR Cadaverine can be used in a a highly sensitive and robust fluorescent displacement assay, which binds to native LPS strongly, specifically recognizing lipid A, and is competitively displaced by compounds displaying an affinity for lipid A.

HY-D1490

Fast red TR salt hemi(zinc chloride)
Dyes

Fast red TR salt hemi (zinc chloride) is a diazonium dye with red color.
HY-D1735

BODIPY TR Ceramide
Golgi-Red Tracke
Fluorescent Dyes/Probes

BODIPY TR Ceramide (Golgi-Red Tracke) is a red-fluorescent probe of the Golgi apparatus in live cells (Ex=589 nm, Em=616 nm).

HY-W414380

Bdp tr nhs ester

Fluorescent Dyes/Probes

Bdp tr nhs ester is a chemiluminescent coupling compound with a long excited state lifetime for immunoassays and is suitable for microscopy and fluorescence polarization analysis applications. NHS ester can react specifically and efficiently with the side chains of primary amines such as lysine residues or amino silane coated surfaces under neutral or weakly basic conditions to form covalent bonds.

HY-110211

BODIPY TMR-X SE	Protein Labeling
BODIPY TMR-X SE is a potent fluorescent dye. BODIPY TMR-X SE can be used to label the primary amines (R-NH₂) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. BODIPY TR-X binds to protein or antibody and has bright, orange fluorescent light. (λ_ex=544 nm, λ_em=570 nm).

Cat. No.	Product Name	Target	Category

HY-129150

Ganoderic acid TR	Influenza Virus	Terpenoids Triterpenes Classification of Application Fields Disease Research Fields Infection Source classification Plants Polyporaceae Ganoderma lucidum (Leyss. Ex Fr.) Karst.
Ganoderic acid TR is a broad-spectrum inhibitor against influenza neuraminidases (NAs), particularly H5N1 and H1N1 neuraminidases. The IC₅₀ values of 10.9 and 4.6 μM, respectively.

HY-N0510

Aristolochic acid A Aristolochic acid I; TR 1736	NF-κB	Alkaloids Other Alkaloids Classification of Application Fields Disease Research Fields Cancer Source classification Plants other families Aristolochiaceae Aristolochia debilis Sieb. et Zucc.
Aristolochic acid A (Aristolochic acid I; TR 1736) is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines.

HY-A0070A

Liothyronine Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3	Thyroid Hormone Receptor Endogenous Metabolite	Ketones, Aldehydes, Acids Monophenols Phenols Disease Research Fields Classification of Application Fields Endocrinology Source classification Endogenous metabolite Disease markers Endocrine diseases
Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively.

HY-N2264

Wulignan A1	Influenza Virus	Phenylpropanoids Lignans Phenols Polyphenols Classification of Application Fields Disease Research Fields Infection Source classification Plants Schisandraceae Schisandra chinensis (Turcz.) Baill.
Wulignan A1 is isolated from the stems of Schisandra henryi. Wulignan A1 exhibits anti-influenza virus H1N1 and *H1N1-TR* (a Tamiflu drug resistant virus strain) activities.

Species:	Human (15) Rhesus Macaque (3) Mouse (8) Rat (1) Cynomolgus (1) Pig (2)
Tag:	His (18) SUMO (1) Myc (1) Fc (12) Flag (1)
Source:	HEK293 (25) CHO (1) Sf9 insect cells (2) E. coli (2)

Cat. No.	Product Name	Species	Source

HY-P77258

TRXR1/TXNRD1 Protein, Human (His)
Thioredoxin reductase 1, cytoplasmic; GRIM-12; Thioredoxin reductase TR1; TR; KDRF
Human E. coli
HY-P71069

TFRC Protein, Human (HEK293, His)
Transferrin receptor protein 1; TR; TfR; Trfr; T9; p90
Human HEK293
HY-P74526

TFRC Protein, Human (HEK293, hFc)
Transferrin receptor protein 1; TR; TfR; Trfr; T9; p90
Human HEK293
HY-P72455

TFRC Protein, Mouse (HEK 293, His)
Transferrin receptor protein 1; TR; TfR; TfR1; Trfr; CD71; Tfrc
Mouse HEK293
HY-P77501

TFRC Protein, Cynomolgus/Rhesus Macaque (HEK293, His)
Transferrin receptor protein 1; TR; TfR; TfR1; Trfr; CD71; Tfrc
Rhesus Macaque HEK293

HY-P7366

HVEM/TNFRSF14 Protein, Human (Sf9, Fc) rHuHVEM, Fc Chimera; TNFRSF14; TR2; CD270; HVEA	Human	Sf9 insect cells
HVEM (herpes virus entry mediator, TNFRSF14, CD270) is a member of the tumor necrosis factor receptor superfamily (TNFRSF). HVEM is a bidirectional molecular switch that transduces positive and negative signals. HVEM can deliver proinflammatory and survival signals when engaged by BTLA or LIGHT, stimulating lymphocyte proliferation, activation, and inducing inflammatory reactions. While, HVEM binds to CD160 and BTLA, inhibiting T- and B-lymphocyte activation and proliferation. HVEM/TNFRSF14 Protein, Human (Sf9, Fc) is a recombinant protein consisting of 146 amino acids (L39-K184) and is produced in Sf9 insect cells.

HY-P77855

TFRC Protein, Cynomolgus (HEK293, His)
TR; TfR1; CD71; sTfR; T9; p90; TFRC; TFR
Cynomolgus HEK293
HY-P78523

TFRC Protein, Human (HEK293, His-Avi)
TR; TfR1; CD71; sTfR; T9; p90; TFRC; TFR
Human HEK293

HY-P78477

LIGHT/TNFSF14 Trimer Protein, Human (HEK293, His-Flag) CD258; TNFSF14; HVEM-L; LIGHT; LTg; TR2	Human	HEK293
LIGHT/TNFSF14 protein (CD258; TNFRSF14) is a type II transmembrane protein produced by activated T cells. It is a TNFRSF14/HVEM ligand and belongs to the tumor necrosis factor (TNF) family. LIGHT/TNFSF14 is mainly expressed in spleen, with two subtypes: membrane-bound type and soluble type . LIGHT/TNFSF14 protein can be used as immune checkpoint molecule of tumor, and stimulate natural killer cells to produce interferon TFNγ, triggering tumor apoptosis signal . LIGHT/TNFSF14 is also involved in the dominant LTβR-NIK-p52 NF-κB pathway promoting the expression of inflammatory gene. In addition, LIGHT/TNFSF14 protein is a co-stimulatory factor that activates lymphoid cells and has an inhibitory effect on herpes virus infection. Human LIGHT/TNFSF14 Protein has 240 amino acids and a transmembrane domain (38-58 a.a.). LIGHT/TNFSF14 Trimer Protein, Human (HEK293, His-Flag) is the extracellular part (S89-V240) of human LIGHT/TNFSF14 Protein, produced by HEK293 cells, with N-terminal His- and Flag-tag.

HY-P75540

ACP5 Protein, Mouse (HEK293, His)
Tartrate-resistant acid phosphatase type 5; TR-AP; TrATPase; T5ap; Trap
Mouse HEK293
HY-P75561

ACP5 Protein, Human (HEK293, His)
Tartrate-resistant acid phosphatase type 5; TR-AP; TrATPase; T5ap; Trap
Human HEK293

HY-P73109

HVEM/TNFRSF14 Protein, Mouse (CHO, His-Fc) Tumor Necrosis Factor Receptor Superfamily Member 14; TR2; CD270; TNFRSF14; HVEA; HVEM	Mouse	CHO
HVEM (herpes virus entry mediator, TNFRSF14, CD270) is a member of the tumor necrosis factor receptor superfamily (TNFRSF). HVEM is a bidirectional molecular switch that transduces positive and negative signals. HVEM can deliver proinflammatory and survival signals when engaged by BTLA or LIGHT, stimulating lymphocyte proliferation, activation, and inducing inflammatory reactions. While, HVEM binds to CD160 and BTLA, inhibiting T- and B-lymphocyte activation and proliferation. HVEM/TNFRSF14 Protein, Mouse (CHO, His-Fc) is a recombinant protein with a C-Terminal Fc label and a C-Terminal His label, It consists of 206 amino acids (M1-Q206) and is produced in CHO cells.

HY-P73107

HVEM/TNFRSF14 Protein, Human (HEK293, His-Fc) Tumor Necrosis Factor Receptor Superfamily Member 14; TR2; CD270; TNFRSF14; HVEA; HVEM	Human	HEK293
HVEM (herpes virus entry mediator, TNFRSF14, CD270) is a member of the tumor necrosis factor receptor superfamily (TNFRSF). HVEM is a bidirectional molecular switch that transduces positive and negative signals. HVEM can deliver proinflammatory and survival signals when engaged by BTLA or LIGHT, stimulating lymphocyte proliferation, activation, and inducing inflammatory reactions. While, HVEM binds to CD160 and BTLA, inhibiting T- and B-lymphocyte activation and proliferation. HVEM/TNFRSF14 Protein, Human (HEK293, His-Fc) is a recombinant protein with a C-Terminal Fc label and a C-Terminal His label, It consists of 202 amino acids (M1-V202) and is produced in HEK293 cells.

HY-P73108

HVEM/TNFRSF14 Protein, Mouse (HEK293, His-Fc) Tumor Necrosis Factor Receptor Superfamily Member 14; TR2; CD270; TNFRSF14; HVEA; HVEM	Mouse	HEK293
HVEM (herpes virus entry mediator, TNFRSF14, CD270) is a member of the tumor necrosis factor receptor superfamily (TNFRSF). HVEM is a bidirectional molecular switch that transduces positive and negative signals. HVEM can deliver proinflammatory and survival signals when engaged by BTLA or LIGHT, stimulating lymphocyte proliferation, activation, and inducing inflammatory reactions. While, HVEM binds to CD160 and BTLA, inhibiting T- and B-lymphocyte activation and proliferation. HVEM/TNFRSF14 Protein, Mouse (HEK293, His-Fc) is a recombinant protein with a C-Terminal Fc label and a C-Terminal His label, It consists of 206 amino acids (M1-Q206) and is produced in HEK293 cells.

HY-P76684

TMEFF1/Tomoregulin-1 Protein, Human (HEK293, Fc)
TR-1; H7365; Transmembrane protein with EGF-like and one follistatin-like domain; C9orf2
Human HEK293
HY-P77252

TMEFF1/Tomoregulin-1 Protein, Mouse (HEK293, Fc)
TR-1; H7365; Transmembrane protein with EGF-like and one follistatin-like domain; C9orf2
Mouse HEK293
HY-P73453

Transferrin Protein, Mouse (HEK293, His)
Serotransferrin; Transferrin; Beta-1 metal-binding globulin; Siderophilin; TF; TRF
Mouse HEK293
HY-P73454

Transferrin Protein, Rat (HEK293, His)
Serotransferrin; Transferrin; Beta-1 metal-binding globulin; Siderophilin; TF; TRF
Rat HEK293
HY-P73581

Transferrin Protein, Mouse (HEK293, Fc)
Serotransferrin; Transferrin; Beta-1 metal-binding globulin; Siderophilin; TF; TRF
Mouse HEK293
HY-P74494

Transferrin Protein, Pig (HEK293, His)
Serotransferrin; Transferrin; Beta-1 metal-binding globulin; Siderophilin; TF; TRF
Pig HEK293
HY-P74495

Transferrin Protein, Pig (HEK293, hFc)
Serotransferrin; Transferrin; Beta-1 metal-binding globulin; Siderophilin; TF; TRF
Pig HEK293

HY-P73106

HVEM/TNFRSF14 Protein, Human (202a.a, HEK293, His) Tumor Necrosis Factor Receptor Superfamily Member 14; TR2; CD270; TNFRSF14; HVEA; HVEM	Human	HEK293
HVEM (herpes virus entry mediator, TNFRSF14, CD270) is a member of the tumor necrosis factor receptor superfamily (TNFRSF). HVEM is a bidirectional molecular switch that transduces positive and negative signals. HVEM can deliver proinflammatory and survival signals when engaged by BTLA or LIGHT, stimulating lymphocyte proliferation, activation, and inducing inflammatory reactions. While, HVEM binds to CD160 and BTLA, inhibiting T- and B-lymphocyte activation and proliferation. HVEM/TNFRSF14 Protein, Human (202a.a, HEK293, His) is a recombinant protein with a C-Terminal His label, It consists of 202 amino acids (M1-V202) and is produced in HEK293 cells.

HY-P700470

TMEFF2/Tomoregulin-2 Protein, Human (HEK293, His) TMEFF2; transmembrane protein with EGF like and two follistatin like domains 2; TR; HPP1; TPEF; TR-2; TENB2; CT120.2; tomoregulin-2; cancer/testis antigen family 120, member 2; hyperplastic polyposis protein 1; transmembrane protein TENB2; transmembrane protein with EGF-like and two follistatin-like domains	Human	HEK293

HY-P75306

DcR3/TNFRSF6B Protein, Human (sf9, hFc) Tumor necrosis factor receptor superfamily member 6B; Decoy receptor 3; TNFRSF6B; DCR3; TR6	Human	Sf9 insect cells
DcR3 is a secreted member of the Tumor Necrosis Factor (TNF) receptor superfamily, recognized as a significant anti-apoptotic factor with prominent involvement in various inflammatory and neoplastic conditions. DcR3 can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL against apoptosis. DcR3 has been associated with tumorigenesis and metastasis, via DcR3/STAT1/IRF1 feedback loop. DcR3/TNFRSF6B Protein, Human (sf9, hFc) has a full length of 300 amino acids (M1-H300), produced in sf9 insect cells with C-terminal hFc-tag.

HY-P70951

HVEM/TNFRSF14 Protein, Rhesus macaque (HEK293, Fc) Tumor Necrosis Factor Receptor Superfamily Member 14; Herpes Virus Entry Mediator A; Herpesvirus Entry Mediator A; HveA; Tumor Necrosis Factor Receptor-Like 2; TR2; CD270; TNFRSF14; HVEA; HVEM	Rhesus Macaque	HEK293
HVEM (herpes virus entry mediator, TNFRSF14, CD270) is a member of the tumor necrosis factor receptor superfamily (TNFRSF). HVEM is a bidirectional molecular switch that transduces positive and negative signals. HVEM can deliver proinflammatory and survival signals when engaged by BTLA or LIGHT, stimulating lymphocyte proliferation, activation, and inducing inflammatory reactions. While, HVEM binds to CD160 and BTLA, inhibiting T- and B-lymphocyte activation and proliferation. HVEM/TNFRSF14 Protein, Rhesus macaque (HEK293, Fc) is a recombinant protein with a C-Terminal Fc label, It consists of 167 amino acids (P37-V203) and is produced in HEK293 cells.

HY-P71992

HVEM/TNFRSF14 Protein, Mouse (HEK293, Fc) Tnfrsf14; hvem; Tumor necrosis factor receptor superfamily member 14; Herpes virus entry mediator A; Herpesvirus entry mediator A; HveA; Tumor necrosis factor receptor-like 2; TR2; CD antigen CD270	Mouse	HEK293
HVEM (herpes virus entry mediator, TNFRSF14, CD270) is a member of the tumor necrosis factor receptor superfamily (TNFRSF). HVEM is a bidirectional molecular switch that transduces positive and negative signals. HVEM can deliver proinflammatory and survival signals when engaged by BTLA or LIGHT, stimulating lymphocyte proliferation, activation, and inducing inflammatory reactions. While, HVEM binds to CD160 and BTLA, inhibiting T- and B-lymphocyte activation and proliferation. HVEM/TNFRSF14 Protein, Mouse (HEK293, Fc) is a recombinant protein with a C-Terminal Fc label, It consists of 169 amino acids (Q39-V207) and is produced in HEK293 cells.

HY-P700452

HVEM/TNFRSF14 Protein, Human (HEK293, hFc) Tumor Necrosis Factor Receptor Superfamily Member 14; Herpes Virus Entry Mediator A; Herpesvirus Entry Mediator A; HveA; Tumor Necrosis Factor Receptor-Like 2; TR2; CD270; TNFRSF14; HVEA; HVEM	Human	HEK293

HY-P70489

HVEM/TNFRSF14 Protein, Human (164a.a, HEK293, His) Tumor Necrosis Factor Receptor Superfamily Member 14; Herpes Virus Entry Mediator A; Herpesvirus Entry Mediator A; HveA; Tumor Necrosis Factor Receptor-Like 2; TR2; CD270; TNFRSF14; HVEA; HVEM	Human	HEK293
HVEM (herpes virus entry mediator, TNFRSF14, CD270) is a member of the tumor necrosis factor receptor superfamily (TNFRSF). HVEM is a bidirectional molecular switch that transduces positive and negative signals. HVEM can deliver proinflammatory and survival signals when engaged by BTLA or LIGHT, stimulating lymphocyte proliferation, activation, and inducing inflammatory reactions. While, HVEM binds to CD160 and BTLA, inhibiting T- and B-lymphocyte activation and proliferation. HVEM/TNFRSF14 Protein, Human (164a.a, HEK293, His) is a recombinant protein with a C-Terminal His label, It consists of 164 amino acids (L39-V202) and is produced in HEK293 cells.

HY-P70184

HVEM/TNFRSF14 Protein, Rhesus macaque (HEK293, His) rRhTNF receptor superfamily member 14/HVEM, His ; Tumor Necrosis Factor Receptor Superfamily Member 14; Herpes Virus Entry Mediator A; Herpesvirus Entry Mediator A; HveA; Tumor Necrosis Factor Receptor-Like 2; TR2; CD270; TNFRSF14; HVEA; HVEM	Rhesus Macaque	HEK293
HVEM (herpes virus entry mediator, TNFRSF14, CD270) is a member of the tumor necrosis factor receptor superfamily (TNFRSF). HVEM is a bidirectional molecular switch that transduces positive and negative signals. HVEM can deliver proinflammatory and survival signals when engaged by BTLA or LIGHT, stimulating lymphocyte proliferation, activation, and inducing inflammatory reactions. While, HVEM binds to CD160 and BTLA, inhibiting T- and B-lymphocyte activation and proliferation. HVEM/TNFRSF14 Protein, Rhesus macaque (HEK293, His) is a recombinant protein with a C-Terminal His label, It consists of 165 amino acids (L39-V203) and is produced in HEK293 cells.

HY-P71548

JMJD1C Protein, Human (His-SUMO-Myc) Jmjd1c; Jumonji domain containing 1C ; Jumonji domain-containing protein 1C; Probable JmjC domain-containing histone demethylation protein 2C; Thryoid receptor interacting protein; Thyroid receptor-interacting protein 8; TR-interacting protein 8; TRIP-8; TRIP8	Human	E. coli

Cat. No.	Product Name