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Results for "

Tachykinin receptor

" in MCE Product Catalog:

By Targets:	Neurokinin Receptor (36)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Endocrinology (20) Infection (1) Inflammation/Immunology (1) Neurological Disease (34)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Natural
Products

Targets Recommended: Neurokinin Receptor

Cat. No.	Product Name	Target	Research Areas

HY-151413

MEN 10207	Neurokinin Receptor	Neurological Disease
MEN 10207 is a selective NK-2 tachykinin receptor (Neurokinin Receptor)?antagonist. MEN 10207 has pA₂ values of 5.2, 7.9 and 4.9 in three monoreceptor in vitro assays for NK-1, NK-2 and NK-3 tachykinin receptors, respectively.

HY-P3851

(β-Ala8)-Neurokinin A (4-10)	Neurokinin Receptor	Neurological Disease
(β-Ala8)-Neurokinin A (4-10), a neuropeptide, is a potent and selective NK-2 tachykinin receptor (Neurokinin Receptor) agonist.

HY-P3802

[D-Trp2,7,9] Substance P	Neurokinin Receptor	Neurological Disease
[D-Trp2,7,9] Substance P is a *tachykinin* (Neurokinin Receptor) antagonist with K_i values of 1 μM, 1.3 μM, and ~9 μM for NK-1, NK-2,and NK-3 receptor, respectively.

HY-108482

CP-96,345	Neurokinin Receptor	Inflammation/Immunology Neurological Disease
CP-96,345 is a specific, highly potent, and orally active *tachykinin* and substance P receptor non-peptide inhibitor. CP-96,345 prevents the drop in blood pressure evoked by substance P and neurokinin A. CP-96,345 can be used for researching neurogenic inflammation.

HY-P0187

Senktide
Neurokinin Receptor Neurological Disease Endocrinology

Senktide is a tachykinin NK₃ receptor agonist.
HY-P0236

Neurokinin A(4-10)
Neurokinin Receptor Neurological Disease Endocrinology

Neurokinin A (4-10) is a tachykinin NK₂ receptor agonist.
HY-P0236A

Neurokinin A(4-10) TFA
Neurokinin Receptor Neurological Disease Endocrinology

Neurokinin A (4-10) TFA is a tachykinin NK₂ receptor agonist.
HY-U00207

MEN11467
Neurokinin Receptor Neurological Disease Endocrinology

MEN11467 is a selective and orally- effective peptidomimetic tachykinin NK₁ receptor antagonist.
HY-14770

Ibodutant
MEN 15596
Neurokinin Receptor Neurological Disease Endocrinology

Ibodutant (MEN 15596) is a potent and selective tachykinin NK2 receptor antagonist with a pK_i of 10.1.
HY-19670

Befetupitant
Ro67-5930
Neurokinin Receptor Neurological Disease Endocrinology

Befetupitant is a high-affinity, nonpeptide, competitive tachykinin 1 receptor (NK1R) antagonist.

Senktide	Neurokinin Receptor	Neurological Disease Endocrinology
Senktide is a tachykinin NK₃ receptor agonist.

Neurokinin A(4-10)	Neurokinin Receptor	Neurological Disease Endocrinology
Neurokinin A (4-10) is a **tachykinin NK₂ receptor** agonist.

Neurokinin A(4-10) TFA	Neurokinin Receptor	Neurological Disease Endocrinology
Neurokinin A (4-10) TFA is a **tachykinin NK₂ receptor** agonist.

MEN11467	Neurokinin Receptor	Neurological Disease Endocrinology
MEN11467 is a selective and orally- effective peptidomimetic **tachykinin NK₁ receptor** antagonist.

Ibodutant MEN 15596	Neurokinin Receptor	Neurological Disease Endocrinology
Ibodutant (MEN 15596) is a potent and selective **tachykinin NK2 receptor antagonist with a pK_i** of 10.1.

Befetupitant Ro67-5930	Neurokinin Receptor	Neurological Disease Endocrinology
Befetupitant is a high-affinity, nonpeptide, competitive tachykinin 1 receptor (NK1R) antagonist.

HY-U00392

Tachykinin angatonist 1	Neurokinin Receptor	Neurological Disease Endocrinology
Tachykinin angatonist 1 is a neurokinin receptor antagonist extracted from patent US5968923, compound example 32.

HY-P0255

Physalaemin
Neurokinin Receptor Neurological Disease Endocrinology

Physalaemin, a non-mammalian tachykinin, binds selectively to neurokinin-1 (NK1) receptor with high affinity.

Physalaemin	Neurokinin Receptor	Neurological Disease Endocrinology
Physalaemin, a non-mammalian tachykinin, binds selectively to neurokinin-1 (NK1) *receptor* with high affinity.

HY-P1276

Men 10376 Neurokinin-2 receptor antagonist	Neurokinin Receptor	Endocrinology
Men 10376 is a selective **tachykinin NK-2 receptor antagonist, with a K_i** of 4.4 μM for rat small intestine NK-2 receptor.

HY-P1276A

Men 10376 TFA Neurokinin-2 receptor antagonist TFA	Neurokinin Receptor	Endocrinology
Men 10376 TFA is a selective **tachykinin NK-2 receptor antagonist, with a K_i** of 4.4 μM for rat small intestine NK-2 receptor.

HY-P1017

MDL 29913	Neurokinin Receptor	Neurological Disease Cardiovascular Disease
MDL 29913, a cyclic pseudopeptide, is a competitive NK₂ tachykinin receptor selective antagonist, with a pA₂ of 8.66.

HY-12142

Vofopitant GR 205171	Neurokinin Receptor	Neurological Disease Endocrinology
Vofopitant is potent **tachykinin NK₁ receptor antagonist, with pK_i*s of 10.6, 9.5, and 9.8 for human, rat and ferret NK₁ receptor*, respectively.

HY-P1186

Eledoisin Related Peptide Eledoisin-Related Peptide; Eledoisin RP	Neurokinin Receptor	Neurological Disease
Eledoisin Related Peptide is a Substance P analog that excites neurons and triggers behavioral responses. Eledoisin Related Peptide is also a **tachykinin receptor** ligand.

HY-P3092

Phyllomedusin	Neurokinin Receptor	Neurological Disease
Phyllomedusin, an tachykinin decapeptide, is a NK1 receptor agonist. Phyllomedusin has vasodilating activity and provokes the contraction of the pylorus.

HY-P1012

[Sar9,Met(O2)11]-Substance P
Neurokinin Receptor Neurological Disease Endocrinology

[Sar9,Met(O2)11]-Substance P is a tachykinin NK₁ receptor selective agonist.
HY-P1012A

[Sar9,Met(O2)11]-Substance P TFA
Neurokinin Receptor Neurological Disease Endocrinology

[Sar9,Met(O2)11]-Substance P TFA is a tachykinin NK₁ receptor selective agonist.
HY-P2475

[Pro9]-Substance P
Neurokinin Receptor Neurological Disease

[Pro9]-Substance P is a potent, reversible and selective agonist of NK-1 tachykinin receptors with an EC₅₀ of 0.93 nM.

[Sar9,Met(O2)11]-Substance P	Neurokinin Receptor	Neurological Disease Endocrinology
[Sar9,Met(O2)11]-Substance P is a **tachykinin NK₁ receptor** selective agonist.

[Sar9,Met(O2)11]-Substance P TFA	Neurokinin Receptor	Neurological Disease Endocrinology
[Sar9,Met(O2)11]-Substance P TFA is a **tachykinin NK₁ receptor** selective agonist.

[Pro9]-Substance P	Neurokinin Receptor	Neurological Disease
[Pro9]-Substance P is a potent, reversible and selective agonist of NK-1 tachykinin receptors with an EC₅₀ of 0.93 nM.

HY-P3890

Substance P (5-11)	Neurokinin Receptor	Neurological Disease
Substance P (5-11), the C-terminal heptapeptide of Substance P (Substance P (HY-P0201)), is a neuropeptide. Substance P (5-11) binds to NK-1 tachykinin receptor.

HY-P0197

Neurokinin A Substance K; Neurokinin α; Neuromedin L	Neurokinin Receptor	Neurological Disease Endocrinology
Neurokinin A (Substance K), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues.

HY-108479

Nolpitantium SR140333	Neurokinin Receptor	Neurological Disease
Nolpitantium (SR140333) is a potent, selective, competitive, non-peptide tachykinin NK₁ receptor antagonist. Nolpitantium blocks the activation of rat thalamic neurons after nociceptive stimulation.

HY-P0197A

Neurokinin A TFA Substance K TFA; Neurokinin α TFA; Neuromedin L TFA	Neurokinin Receptor	Endocrinology Neurological Disease
Neurokinin A TFA (Substance K TFA), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues.

HY-P1198

Hemokinin 1, human	Neurokinin Receptor	Neurological Disease
Hemokinin 1, human is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. Hemokinin 1, human is a full agonist at NK2 and NK3 receptor. Hemokinin 1, human can produces an opioid-independent analgesia.

HY-P1192

GR-73632	Neurokinin Receptor	Neurological Disease Endocrinology
GR-73632 is a novel tachykinin neurokinin 1 (NK-1) receptor agonist. GR-73632 acts directly on the peripheral terminals of primary sensory neurons through NK1 receptor which convey itch signals.

HY-P1198A

Hemokinin 1, human TFA	Neurokinin Receptor	Neurological Disease
Hemokinin 1, human TFA is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. Hemokinin 1, human TFA is a full agonist at NK2 and NK3 receptor. Hemokinin 1, human TFA can produces an opioid-independent analgesia.

HY-14406A

L-733060 hydrochloride	Neurokinin Receptor	Cancer Neurological Disease
L-733060 hydrochloride is a potent tachykinin NK₁ receptor antagonist. L-733060 hydrochloride inhibits neurogenic plasma extravasation at doses that do not cause adverse cardiovascular effects in rodents and also acts as an antitumoral agent.

HY-P3861

Biotin-NeurokininA	Neurokinin Receptor	Neurological Disease
Biotin-NeurokininA is a biotinylated NeurokininA (HY-P0197). Neurokinin A (Substance K), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues.

HY-P0242

Neurokinin B	Neurokinin Receptor	Neurological Disease Endocrinology
Neurokinin B belongs to the tachykinin family of peptides. Neurokinin B binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R-to mediate their biological effect.

HY-P3799

[Glp6] Substance P (6-11)	Neurokinin Receptor	Neurological Disease
[Glp6] Substance P (6-11) is an analogue of substance P (6-11). Substance P (6-11) stimulates [3H]-inositol monophosphate ([3H]-IP1) formation in rat urinary bladder by acting on the 'septide-sensitive' tachykinin receptors.

HY-P0242A

Neurokinin B TFA	Neurokinin Receptor	Neurological Disease Endocrinology
Neurokinin B TFA belongs to the tachykinin family of peptides. Neurokinin B binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R-to mediate their biological effect.

HY-12143

Vofopitant dihydrochloride GR 205171A	Neurokinin Receptor	Cancer Neurological Disease Endocrinology
Vofopitant dihydrochloride (GR 205171A) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist, inhibits [³H]SP binding to the NK1 receptor with pK_i values of 9.5 and 10.6 in rat and human membranes respectively, acts as a potential broad-spectrum anti-emetic agent.

HY-19633

CS-003 Free base	Neurokinin Receptor	Infection Endocrinology
CS-003 Free base (CS-003), a triple tachykinin receptor antagonist, shows high affinities for human (Neurokinin) NK1, NK2 and NK3 receptors with K_i values of 2.3 nM, 0.54 nM and 0.74 nM, respectively. CS-003 Free base (CS-003) has therapeutic efficacy on respiratory diseases associated with neurokinins.

HY-P3889

Substance P (6-11)	Neurokinin Receptor	Neurological Disease
Substance P (6-11) is the C-terminal hexapeptideamide of Substance P (Substance P (HY-P0201)). Substance P (6-11) binds to NK-1 tachykinin receptor. Substance P (6-11) shows depolarization of motoneurons and a hypotensive effect.

Cat. No.	Product Name	Target	Research Area

HY-151413

MEN 10207	Neurokinin Receptor	Neurological Disease
MEN 10207 is a selective NK-2 tachykinin receptor (Neurokinin Receptor)?antagonist. MEN 10207 has pA₂ values of 5.2, 7.9 and 4.9 in three monoreceptor in vitro assays for NK-1, NK-2 and NK-3 tachykinin receptors, respectively.

HY-P3851

(β-Ala8)-Neurokinin A (4-10)	Neurokinin Receptor	Neurological Disease
(β-Ala8)-Neurokinin A (4-10), a neuropeptide, is a potent and selective NK-2 tachykinin receptor (Neurokinin Receptor) agonist.

HY-P3802

[D-Trp2,7,9] Substance P	Neurokinin Receptor	Neurological Disease
[D-Trp2,7,9] Substance P is a *tachykinin* (Neurokinin Receptor) antagonist with K_i values of 1 μM, 1.3 μM, and ~9 μM for NK-1, NK-2,and NK-3 receptor, respectively.

HY-P0187

Senktide
Neurokinin Receptor Neurological Disease Endocrinology

Senktide is a tachykinin NK₃ receptor agonist.
HY-P0236

Neurokinin A(4-10)
Neurokinin Receptor Neurological Disease Endocrinology

Neurokinin A (4-10) is a tachykinin NK₂ receptor agonist.
HY-P0236A

Neurokinin A(4-10) TFA
Neurokinin Receptor Neurological Disease Endocrinology

Neurokinin A (4-10) TFA is a tachykinin NK₂ receptor agonist.

Senktide	Neurokinin Receptor	Neurological Disease Endocrinology
Senktide is a tachykinin NK₃ receptor agonist.

Neurokinin A(4-10)	Neurokinin Receptor	Neurological Disease Endocrinology
Neurokinin A (4-10) is a **tachykinin NK₂ receptor** agonist.

Neurokinin A(4-10) TFA	Neurokinin Receptor	Neurological Disease Endocrinology
Neurokinin A (4-10) TFA is a **tachykinin NK₂ receptor** agonist.

HY-P1276

Men 10376 Neurokinin-2 receptor antagonist	Neurokinin Receptor	Endocrinology
Men 10376 is a selective **tachykinin NK-2 receptor antagonist, with a K_i** of 4.4 μM for rat small intestine NK-2 receptor.

HY-P1276A

Men 10376 TFA Neurokinin-2 receptor antagonist TFA	Neurokinin Receptor	Endocrinology
Men 10376 TFA is a selective **tachykinin NK-2 receptor antagonist, with a K_i** of 4.4 μM for rat small intestine NK-2 receptor.

HY-P1017

MDL 29913	Neurokinin Receptor	Neurological Disease Cardiovascular Disease
MDL 29913, a cyclic pseudopeptide, is a competitive NK₂ tachykinin receptor selective antagonist, with a pA₂ of 8.66.

HY-P1186

Eledoisin Related Peptide Eledoisin-Related Peptide; Eledoisin RP	Neurokinin Receptor	Neurological Disease
Eledoisin Related Peptide is a Substance P analog that excites neurons and triggers behavioral responses. Eledoisin Related Peptide is also a **tachykinin receptor** ligand.

HY-P3092

Phyllomedusin	Neurokinin Receptor	Neurological Disease
Phyllomedusin, an tachykinin decapeptide, is a NK1 receptor agonist. Phyllomedusin has vasodilating activity and provokes the contraction of the pylorus.

HY-P1012

[Sar9,Met(O2)11]-Substance P
Neurokinin Receptor Neurological Disease Endocrinology

[Sar9,Met(O2)11]-Substance P is a tachykinin NK₁ receptor selective agonist.
HY-P1012A

[Sar9,Met(O2)11]-Substance P TFA
Neurokinin Receptor Neurological Disease Endocrinology

[Sar9,Met(O2)11]-Substance P TFA is a tachykinin NK₁ receptor selective agonist.
HY-P2475

[Pro9]-Substance P
Neurokinin Receptor Neurological Disease

[Pro9]-Substance P is a potent, reversible and selective agonist of NK-1 tachykinin receptors with an EC₅₀ of 0.93 nM.

HY-P3890

Substance P (5-11)	Neurokinin Receptor	Neurological Disease
Substance P (5-11), the C-terminal heptapeptide of Substance P (Substance P (HY-P0201)), is a neuropeptide. Substance P (5-11) binds to NK-1 tachykinin receptor.

HY-P1193

GR 82334	Peptides	Neurological Disease
GR 82334 is a potent and specific reversible **tachykinin NK1 receptor** antagonist. GR 82334 inhibits substance P-induced sensitization by blocking SP NK1 receptors in naked mole-rats.

HY-P0197

Neurokinin A Substance K; Neurokinin α; Neuromedin L	Neurokinin Receptor	Neurological Disease Endocrinology
Neurokinin A (Substance K), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues.

HY-P0197A

Neurokinin A TFA Substance K TFA; Neurokinin α TFA; Neuromedin L TFA	Neurokinin Receptor	Endocrinology Neurological Disease
Neurokinin A TFA (Substance K TFA), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues.

HY-P1198

Hemokinin 1, human	Neurokinin Receptor	Neurological Disease
Hemokinin 1, human is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. Hemokinin 1, human is a full agonist at NK2 and NK3 receptor. Hemokinin 1, human can produces an opioid-independent analgesia.

HY-P1192

GR-73632	Neurokinin Receptor	Neurological Disease Endocrinology
GR-73632 is a novel tachykinin neurokinin 1 (NK-1) receptor agonist. GR-73632 acts directly on the peripheral terminals of primary sensory neurons through NK1 receptor which convey itch signals.

HY-P1198A

Hemokinin 1, human TFA	Neurokinin Receptor	Neurological Disease
Hemokinin 1, human TFA is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. Hemokinin 1, human TFA is a full agonist at NK2 and NK3 receptor. Hemokinin 1, human TFA can produces an opioid-independent analgesia.

HY-P3861

Biotin-NeurokininA	Neurokinin Receptor	Neurological Disease
Biotin-NeurokininA is a biotinylated NeurokininA (HY-P0197). Neurokinin A (Substance K), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues.

HY-P0242

Neurokinin B	Neurokinin Receptor	Neurological Disease Endocrinology
Neurokinin B belongs to the tachykinin family of peptides. Neurokinin B binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R-to mediate their biological effect.

HY-P3799

[Glp6] Substance P (6-11)	Neurokinin Receptor	Neurological Disease
[Glp6] Substance P (6-11) is an analogue of substance P (6-11). Substance P (6-11) stimulates [3H]-inositol monophosphate ([3H]-IP1) formation in rat urinary bladder by acting on the 'septide-sensitive' tachykinin receptors.

HY-P0242A

Neurokinin B TFA	Neurokinin Receptor	Neurological Disease Endocrinology
Neurokinin B TFA belongs to the tachykinin family of peptides. Neurokinin B binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R-to mediate their biological effect.

HY-P3889

Substance P (6-11)	Neurokinin Receptor	Neurological Disease
Substance P (6-11) is the C-terminal hexapeptideamide of Substance P (Substance P (HY-P0201)). Substance P (6-11) binds to NK-1 tachykinin receptor. Substance P (6-11) shows depolarization of motoneurons and a hypotensive effect.

Cat. No.	Product Name	Target	Research Area

HY-108482

CP-96,345	Neurokinin Receptor	Inflammation/Immunology Neurological Disease
CP-96,345 is a specific, highly potent, and orally active *tachykinin* and substance P receptor non-peptide inhibitor. CP-96,345 prevents the drop in blood pressure evoked by substance P and neurokinin A. CP-96,345 can be used for researching neurogenic inflammation.

Cat. No.	Product Name	Target	Category

HY-P0255

Physalaemin	Neurokinin Receptor	Phenols Ketones, Aldehydes, Acids Classification of Application Fields Disease Research Fields Endocrinology Neurological Disease Source classification Animals
Physalaemin, a non-mammalian tachykinin, binds selectively to neurokinin-1 (NK1) *receptor* with high affinity.

Tachykinin receptor

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

NaturalProducts

Natural
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