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Results for "

VD/VDR

" in MCE Product Catalog:

By Targets:	VD/VDR (44) Antibiotic (1) Apoptosis (3) Bacterial (1) Caspase (2) Drug Metabolite (1) Endogenous Metabolite (8) HDAC (1) HIV (1) Isotope-Labeled Compounds (1) RAR/RXR (1) Ser/Thr Protease (1) Sodium Channel (1)
By Research Areas:	Cancer (18) Endocrinology (1) Infection (3) Inflammation/Immunology (4) Metabolic Disease (26) Neurological Disease (1)

Inhibitors & Agonists

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Targets Recommended: VD/VDR

Cat. No.	Product Name	Target	Research Areas

HY-145263

VD2173	Ser/Thr Protease	Cancer
VD2173 is a side chain cyclized macrocyclic peptide inhibitor of HGF-activating serine proteases. VD2173 potently inhibits matriptase and hepsin. VD2173 can be used for the research of lung cancer.

HY-15330

VD2-d3
VD/VDR Metabolic Disease

VD2-d₃ is the deuterium labeled vitamin D2.
HY-15328

25-Hydroxy VD2-d6
VD/VDR Metabolic Disease

25-Hydroxy VD2-d₆ is the deuterium labeled 25-Hydroxy VD2.

VD2-d3	VD/VDR	Metabolic Disease
VD2-d₃ is the deuterium labeled vitamin D2.

25-Hydroxy VD2-d6	VD/VDR	Metabolic Disease
25-Hydroxy VD2-d₆ is the deuterium labeled 25-Hydroxy VD2.

HY-114310

VDR agonist 1	VD/VDR Apoptosis	Cancer
VDR agonist 1 (compound 28) is a nonsteroidal Vitamin D receptor (VDR) agonist, with an IC₅₀ of 690 nM in MCF-7 cells. VDR agonist 1 arrests the cell cycle through the up-regulation of p21 and p27, promotes apoptosis by increasing the expression of BAX and decrease the expression of Bcl-2.

HY-15327

1alpha, 25-Dihydroxy VD2-d6
Isotope-Labeled Compounds VD/VDR Metabolic Disease

1alpha, 25-Dihydroxy VD2-d₆6 is a deuterated form of vitamin D.

1alpha, 25-Dihydroxy VD2-d6	Isotope-Labeled Compounds VD/VDR	Metabolic Disease
1alpha, 25-Dihydroxy VD2-d₆6 is a deuterated form of vitamin D.

HY-12305A

(R)-Q-VD-OPh (R)-QVD-OPH; (R)-Quinoline-Val-Asp-Difluorophenoxymethylketone	Apoptosis	Cancer
(R)-Q-VD-OPh ((R)-QVD-OPH) is the less active enantiomer of Q-VD-OPha. Q-VD-OPha is an irreversible pan-caspase inhibitor with potent antiapoptotic properties.

HY-12305

Q-VD-OPh QVD-OPH; Quinoline-Val-Asp-Difluorophenoxymethylketone	Caspase HIV	Cancer Infection
Q-VD-OPh is an irreversible pan-caspase inhibitor with potent antiapoptotic properties; inhibits caspase 7 with an IC₅₀ of 48 nM and 25-400 nM for other caspases including caspase 1, 3, 8, 9, 10, and 12. Q-VD-OPh can inhibits HIV infection. Q-VD-OPh is able to cross the blood-brain barrier.

HY-15156

1alpha, 24, 25-Trihydroxy VD2
VD/VDR Metabolic Disease

1alpha, 24, 25-Trihydroxy VD2 is a vitamin D analog.

1alpha, 24, 25-Trihydroxy VD2	VD/VDR	Metabolic Disease
1alpha, 24, 25-Trihydroxy VD2 is a vitamin D analog.

HY-76915

24, 25-Dihydroxy VD3	VD/VDR Endogenous Metabolite	Metabolic Disease
24, 25-Dihydroxy VD3 is a compound closely related to 1,25-dihydroxyvitamin D3 and is the active form of vitamin D3.

HY-107218

11-Hydroxysugiol
RAR/RXR VD/VDR Infection

11-Hydroxysugiol regulates the SUMOylation of intracellular receptors by modulating RARα and vitamin D₃ receptor (VDR).
HY-15331

VD3-d6
Vitamin D3-26,26,26,27,27,27-d₆
VD/VDR Metabolic Disease

VD3-d₆ is the deuterium labeled Vitamin D3; tools for determination of Vitamin D3 metabolites in human serum.
HY-15157

Calcitetrol
1α, 24, 25-Trihydroxy VD3
VD/VDR Metabolic Disease

Calcitetrol(1α, 24, 25-Trihydroxy VD3) is the hormonally active form of vitamin D with three hydroxyl groups.

11-Hydroxysugiol	RAR/RXR VD/VDR	Infection
11-Hydroxysugiol regulates the SUMOylation of intracellular receptors by modulating RARα and vitamin D₃ receptor (VDR).

VD3-d6 Vitamin D3-26,26,26,27,27,27-d₆	VD/VDR	Metabolic Disease
VD3-d₆ is the deuterium labeled Vitamin D3; tools for determination of Vitamin D3 metabolites in human serum.

Calcitetrol 1α, 24, 25-Trihydroxy VD3	VD/VDR	Metabolic Disease
Calcitetrol(1α, 24, 25-Trihydroxy VD3) is the hormonally active form of vitamin D with three hydroxyl groups.

HY-76801

24, 25-Dihydroxy VD2 24,25-Dihydroxy vitamin D2	VD/VDR Drug Metabolite	Metabolic Disease
24, 25-Dihydroxy VD2 is a hydroxylated metabolite of Vitamin D2; a synthetic analog of Vitamin D.

HY-32351S

Calcifediol-d3 25-hydroxy Vitamin D3-d₃	VD/VDR Endogenous Metabolite	Metabolic Disease
Calcifediol-d₃ is a deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR inhibitor[1][2].

HY-100219

CB1151
VD/VDR Cancer

CB1151 is a 20-epi analogue of 1,25 dihydroxyvitamin D3 (VD) with potent anti-tumor effects. CB1151 inhibits MCF-7 cell growth with an IC₅₀ value of 0.82 nM.

CB1151	VD/VDR	Cancer
CB1151 is a 20-epi analogue of 1,25 dihydroxyvitamin D3 (VD) with potent anti-tumor effects. CB1151 inhibits MCF-7 cell growth with an IC₅₀ value of 0.82 nM.

HY-13249

1alpha-Hydroxy VD4 1α-Hydroxy vitamin D4	VD/VDR	Cancer
1alpha-Hydroxy VD4 , a 1alpha(OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells.

HY-32344

Inecalcitol TX 522	VD/VDR Apoptosis	Cancer
Inecalcitol (TX 522), a unique vitamin D3 analog, is an orally active vitamin D receptor (VDR) agonist with a K_d of 0.53 nM. Inecalcitol can induce cell apoptosis and has potent anticancer activities.

HY-12407

ZK168281	VD/VDR	Metabolic Disease
ZK168281 is a 25-carboxylic ester 1α,25(OH)₂D₃ analog and a pure *VDR* antagonist with a K_d value of 0.1 nM. ZK168281 is an effective inhibitor of the coactivator (CoA) interaction of its receptor.

HY-76814

Calcitriol-d6	VD/VDR	Metabolic Disease
Calcitriol-d₆ is the deuterium labeled Calcitriol. Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR)[1].

HY-15329

Maxacalcitol-d6	VD/VDR	Metabolic Disease
Maxacalcitol-d₆6 is the deuterated form of Maxacalcitol (22-Oxacalcitriol), which is a non-calcemic vitamin D3 analog and VDR ligand of VDR-like receptors.

HY-147337

MeTC7
VD/VDR Cancer

MeTC7 is a Vitamin-D receptor (VDR) antagonist. MeTC7 has potent VDR inhibition activity with an IC₅₀ value of 2.9 μM. MeTC7 shows good antitumor effects.
HY-75035

Calcipotriol Impurity C
VD/VDR Inflammation/Immunology

Calcipotriol Impurity C is the impurity of Calcipotriol, Calcipotriol is a ligand of VDR-like receptors.
HY-15265

Impurity F of Calcipotriol
VD/VDR Cancer

Impurity F of Calcipotriol; Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors.

MeTC7	VD/VDR	Cancer
MeTC7 is a Vitamin-D receptor (VDR) antagonist. MeTC7 has potent VDR inhibition activity with an IC₅₀ value of 2.9 μM. MeTC7 shows good antitumor effects.

Calcipotriol Impurity C	VD/VDR	Inflammation/Immunology
Calcipotriol Impurity C is the impurity of Calcipotriol, Calcipotriol is a ligand of VDR-like receptors.

Impurity F of Calcipotriol	VD/VDR	Cancer
Impurity F of Calcipotriol; Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors.

HY-10397A

MX1013 CV1013; Z-VD-FMK	Caspase	Cancer
MX1013 is a potent, irreversible dipeptide caspase inhibitor vith antiapoptotic activity. MX1013 inhibits recombinant human caspase 3 with an IC₅₀ of 30 nM.

HY-15332

Alfacalcidol-d6
VD/VDR Metabolic Disease

Alfacalcidol-d₆ is the deuterium labeled Alfacalcidol. Alfacalcidol is a non-selective VDR activator.
HY-10002

Calcitriol
1,25-Dihydroxyvitamin D3
VD/VDR Endogenous Metabolite Cancer

Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.
HY-32339

Maxacalcitol
22-Oxacalcitriol
VD/VDR Metabolic Disease

Maxacalcitol (22-Oxacalcitriol) is non-calcemic vitamin D3 analog and ligand of VDR-like receptors.

Alfacalcidol-d6	VD/VDR	Metabolic Disease
Alfacalcidol-d₆ is the deuterium labeled Alfacalcidol. Alfacalcidol is a non-selective VDR activator.

Calcitriol 1,25-Dihydroxyvitamin D3	VD/VDR Endogenous Metabolite	Cancer
Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.

Maxacalcitol 22-Oxacalcitriol	VD/VDR	Metabolic Disease
Maxacalcitol (22-Oxacalcitriol) is non-calcemic vitamin D3 analog and ligand of VDR-like receptors.

HY-15264

MC 1046 Impurity A of Calcipotriol	VD/VDR	Cancer
MC 1046(Impurity A of Calcipotriol) is an impurity of Calcipotriol; Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors.

HY-15266

24R-Calcipotriol PRI 2202; Impurity D of Calcipotriol	VD/VDR	Cancer
24R-Calcipotriol(PRI 2202) is an impurity of Calcipotriol; Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors.

HY-131961

Triciferol	VD/VDR HDAC	Cancer
Triciferol functions as a multiple ligand with combined *VDR* agonist and HDAC antagonist activities. Triciferol binds directly to the VDR (IC₅₀=87 nM), and functions as an agonist with 1,25D-like potency on several 1,25D target genes. Triciferol induces marked tubulin hyperacetylation, and augments histone acetylation. Antiproliferative and cytotoxic activities.

HY-32351

Calcifediol 25-hydroxy Vitamin D3	VD/VDR Endogenous Metabolite	Metabolic Disease
Calcifediol (25-hydroxy Vitamin D3), a major circulating metabolite of vitamin D3, is a potent *VDR* inhibitor.

HY-32351A

Calcifediol monohydrate 25-hydroxy Vitamin D3 monohydrate	VD/VDR Endogenous Metabolite	Metabolic Disease
Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), a major circulating metabolite of vitamin D3, is a potent *VDR* inhibitor.

HY-13332

Calcifediol-d6	VD/VDR	Metabolic Disease
Calcifediol-d₆ is the deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR inhibitor[1][2].

HY-13294

Impurity C of Alfacalcidol	VD/VDR	Metabolic Disease
Impurity of Alfacalcidol. Alfacalcidol (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) is a non-selective VDR activator medication.

HY-75041

Calcitriol Impurities A	VD/VDR	Metabolic Disease
Calcitriol Impurities A is the impurity of Calcitriol, Calcitriol is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).

HY-10002S

Calcitriol-13C3 1,25-Dihydroxyvitamin D3-¹³C₃	Sodium Channel	Neurological Disease
Calcitriol-¹³C₃ is the ¹³C-labeled Calcitriol. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.

HY-77274

Calcitriol Impurities D	VD/VDR	Metabolic Disease
Calcitriol Impurities D is the impurity of Calcitriol, Calcitriol is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).

HY-10003

Alfacalcidol 1-hydroxycholecalciferol; 1.alpha.-Hydroxyvitamin D3	VD/VDR	Metabolic Disease
Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective *VDR* activator medication, and widely be used in the management of osteoporosis.

HY-32345

Elocalcitol BXL-628; Ro-26-9228	VD/VDR	Cancer Inflammation/Immunology
Elocalcitol (BXL-628) is a selective, orally active vitamin D receptor (VDR) agonist. Elocalcitol shows anti-inflammatory activity. Elocalcitol inhibits growth of prostate cancer cells.

HY-32351AS

Calcifediol-d6 monohydrate 25-hydroxy Vitamin D3-d₆ (monohydrate)	VD/VDR Endogenous Metabolite	Metabolic Disease
Calcifediol-d₆ (monohydrate) is the deuterium labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), a major circulating metabolite of vitamin D3, is a potent VDR inhibitor[1][2].

HY-10002S1

Calcitriol-d3 1,25-Dihydroxyvitamin D3-d₃	VD/VDR Endogenous Metabolite	Cancer
Calcitriol-d₃ is the deuterium labeled Calcitriol[1]. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist[2][3][4][5].

HY-32351AS1

Calcifediol-13C5 monohydrate 25-hydroxy Vitamin D3-¹³C₅ (monohydrate)	VD/VDR Endogenous Metabolite	Metabolic Disease
Calcifediol-¹³C₅ (monohydrate) is the ¹³C-labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), a major circulating metabolite of vitamin D3, is a potent VDR inhibitor[1][2].

HY-13293

Impurity C of Calcitriol	VD/VDR	Cancer
Impurity C of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).

HY-13292

Impurity B of Calcitriol 1β,25-Dihydroxyvitamin-D3; 1-Epicalcitriol	VD/VDR	Cancer
Impurity B of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).

HY-12398A

TEI-9648	VD/VDR	Metabolic Disease Inflammation/Immunology
TEI-9648, a Vitamin D₃ Lactone analogue, is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9648 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH)₂D₃. TEI-9648 also inhibits HL-60 cell differentiation induced by of 1α,25(OH)₂D₃. TEI-9648 has the potential for bone metabolism research.

HY-10003S

Alfacalcidol-d7 1-hydroxycholecalciferol-d₇; 1.alpha.-Hydroxyvitamin D3-d₇	VD/VDR	Metabolic Disease
Alfacalcidol-d₇ is the deuterium labeled Alfacalcidol. Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective VDR activator medication, and widely be used in the management of osteoporosis[1][2][3][4].

HY-B0975AS

Penicillin V-d5	Bacterial Antibiotic	Infection
Penicillin V-d₅ (Phenoxymethylpenicillin-d5) is the deuterium labeled Penicillin V. Penicillin V (Phenoxymethylpenicillin) is an orally active antibiotic. Penicillin V inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis[1][2][3][4].

HY-12398

TEI-9647	VD/VDR	Metabolic Disease Inflammation/Immunology
TEI-9647, a Vitamin D₃ Lactone analogue, is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9647 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH)₂D₃. TEI-9647 inhibits bone resorption and HL-60 cell differentiation induced by of 1α,25(OH)₂D₃. TEI-9647 has the potential for suppressing the excessive bone resorption and osteoclast formation in Paget's disease.

HY-12397

ZK159222	VD/VDR	Endocrinology
ZK159222, a 25-carboxylic ester analogue of 1α,25-(OH)2D3, is a potent 1α,25-(OH)2D3 receptor (VDR) antagonist. The mechanism of ZK159222 antagonistic action is mediated by a lack of ligand-induced vitamin D receptor interaction with coactivators. ZK159222 has a partial agonistic character.

HY-10002A

(1S)-Calcitriol 1α,25-Dihydroxy-3-epi-vitamin-D3	VD/VDR	Others
(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D₃ (1α,25(OH)₂D₃). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion.

Cat. No.	Product Name	Target	Category

HY-76915

24, 25-Dihydroxy VD3	VD/VDR Endogenous Metabolite	Natural Products Classification of Application Fields Disease Research Fields Metabolic Disease Source classification Endogenous metabolite
24, 25-Dihydroxy VD3 is a compound closely related to 1,25-dihydroxyvitamin D3 and is the active form of vitamin D3.

HY-10002

Calcitriol 1,25-Dihydroxyvitamin D3	VD/VDR Endogenous Metabolite	Natural Products Classification of Application Fields Disease Research Fields Cancer Source classification Endogenous metabolite
Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.

HY-32351

Calcifediol 25-hydroxy Vitamin D3	VD/VDR Endogenous Metabolite	Natural Products Metabolic Disease Disease Research Fields Classification of Application Fields Source classification Endogenous metabolite Disease markers Other disease
Calcifediol (25-hydroxy Vitamin D3), a major circulating metabolite of vitamin D3, is a potent *VDR* inhibitor.

Species:	Human (1) Mouse (1)
Tag:	His (2)
Source:	Sf9 insect cells (2)

Cat. No.	Product Name	Species	Source

HY-P73542

Vitamin D Receptor/VDR Protein, Mouse (sf9, His)
Vitamin D3 receptor; VDR; NR1I1
Mouse Sf9 insect cells
HY-P73543

Vitamin D Receptor/VDR Protein, Human (sf9, His)
Vitamin D3 receptor; VDR; NR1I1
Human Sf9 insect cells

Cat. No.	Product Name

HY-15330

VD2-d3

VD2-d₃ is the deuterium labeled vitamin D2.
HY-15328

25-Hydroxy VD2-d6

25-Hydroxy VD2-d₆ is the deuterium labeled 25-Hydroxy VD2.
HY-15327

1alpha, 25-Dihydroxy VD2-d6

1alpha, 25-Dihydroxy VD2-d₆6 is a deuterated form of vitamin D.
HY-15331

VD3-d6

VD3-d₆ is the deuterium labeled Vitamin D3; tools for determination of Vitamin D3 metabolites in human serum.
HY-32351S

Calcifediol-d3

Calcifediol-d₃ is a deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR inhibitor[1][2].
HY-76814

Calcitriol-d6

Calcitriol-d₆ is the deuterium labeled Calcitriol. Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR)[1].
HY-15329

Maxacalcitol-d6

Maxacalcitol-d₆6 is the deuterated form of Maxacalcitol (22-Oxacalcitriol), which is a non-calcemic vitamin D3 analog and VDR ligand of VDR-like receptors.
HY-15332

Alfacalcidol-d6

Alfacalcidol-d₆ is the deuterium labeled Alfacalcidol. Alfacalcidol is a non-selective VDR activator.
HY-13332

Calcifediol-d6

Calcifediol-d₆ is the deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR inhibitor[1][2].
HY-10002S

Calcitriol-13C3

Calcitriol-¹³C₃ is the ¹³C-labeled Calcitriol. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.

HY-32351AS

Calcifediol-d6 monohydrate
Calcifediol-d₆ (monohydrate) is the deuterium labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), a major circulating metabolite of vitamin D3, is a potent VDR inhibitor[1][2].

HY-10002S1

Calcitriol-d3

Calcitriol-d₃ is the deuterium labeled Calcitriol[1]. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist[2][3][4][5].

HY-32351AS1

Calcifediol-13C5 monohydrate
Calcifediol-¹³C₅ (monohydrate) is the ¹³C-labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), a major circulating metabolite of vitamin D3, is a potent VDR inhibitor[1][2].

HY-10003S

Alfacalcidol-d7
Alfacalcidol-d₇ is the deuterium labeled Alfacalcidol. Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective VDR activator medication, and widely be used in the management of osteoporosis[1][2][3][4].

HY-B0975AS

Penicillin V-d5
Penicillin V-d₅ (Phenoxymethylpenicillin-d5) is the deuterium labeled Penicillin V. Penicillin V (Phenoxymethylpenicillin) is an orally active antibiotic. Penicillin V inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis[1][2][3][4].

VD/VDR

Inhibitors & Agonists

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Natural
Products