1. Search Result
Search Result
Results for "

a1at

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Recombinant Proteins

5

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-134858

    a1at modulator 1

    Serpin Ser/Thr Protease Metabolic Disease
    GSK716 (A1AT modulator 1) is an orally active Z α1-antitrypsin (Z-A1AT) inhibitor with a pIC50 of 8.3. GSK716 binds a cryptic Z α1-antitrypsin pocket, stabilizes monomeric folding intermediates, blocks polymerization, and increases monomer secretion. GSK716 acts on select sensitive α1-antitrypsin variants but fails to affect resistant variants. GSK716 can be used for the research of α1-antitrypsin deficiency and α1-antitrypsin deficiency-associated liver disease [1] .
    GSK716
  • HY-134863

    Serpin Infection Inflammation/Immunology
    A1AT modulator 2 (compound 33) is a modulator of A1AT (α-1 antitrypsin) with an IC50 value of >1.0 μM and an EC50 value of <0.4 μM. A1AT modulator 2 can be used for the research of infection and inflammation [1].
    A1AT modulator 2
  • HY-177619A

    DCR-S1459 sodium

    Serpin Others
    Belcesiran is an alpha 1 antitrypsin (A1AT) inhibitor that acts by allowing the liver to synthesise the A1AT protein and pass it into the bloodstream.
    Belcesiran sodium
  • HY-177619

    DCR-S1459

    Serpin Others
    Belcesiran, a siRNA, is an alpha 1 antitrypsin (A1AT) inhibitor that acts by allowing the liver to synthesise the A1AT protein and pass it into the bloodstream.
    Belcesiran
  • HY-RS12696

    Small Interfering RNA (siRNA) Others

    SERPINA1 Human Pre-designed siRNA Set A contains three designed siRNAs for SERPINA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SERPINA1 Human Pre-designed siRNA Set A
    SERPINA1 Human Pre-designed siRNA Set A

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: