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Results for "

alkaline

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Androgen Receptor (1) Antibiotic (2) Apoptosis (1) Autophagy (4) Bacterial (2) Biochemical Assay Reagents (14) Carbonic Anhydrase (1) Cholinesterase (ChE) (3) COX (1) Cytochrome P450 (1) DNA/RNA Synthesis (1) EBV (1) Endogenous Metabolite (10) Fluorescent Dye (16) HSP (2) IAP (1) Influenza Virus (2) Isotope-Labeled Compounds (4) Leukotriene Receptor (1) MAPKAPK2 (MK2) (2) Mitochondrial Metabolism (1) Parasite (2) Phosphatase (31) Progesterone Receptor (1) Pyk2 (1) Reactive Oxygen Species (4) Thyroid Hormone Receptor (1)
By Research Areas:	Cancer (18) Cardiovascular Disease (1) Endocrinology (4) Infection (5) Inflammation/Immunology (6) Metabolic Disease (18) Neurological Disease (1)
Click Chemistry:	Alkynes (1)

Inhibitors & Agonists

Fluorescent Dye

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Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P2818

Alkaline phosphatase, Bovine intestine 1 Publications Verification Apase	Endogenous Metabolite	Metabolic Disease Cancer
Alkaline phosphatase, Bovine intestine (Apase) is a membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase can be used in molecular biology and enzyme-free analysis. Inhibition of tissue nonspecific alkaline phosphatase can block intracellular lipid accumulation .

HY-78144

4-Methylsalicylic acid	IAP	Inflammation/Immunology
4-Methylsalicylic acid is a salicylic acid. 4-Methylsalicylic acid derivative is a selective *tissue-nonspecific alkaline* phosphatase (TNAP) and intestinal alkaline phosphatase (IAP**) inhibitor .

HY-126606

Isochlortetracycline

Others Infection

Isochlortetracycline is an inactive alkaline degradation product of the Chlortetracycline (HY-B1327A) (broad-spectrum antibiotic) .

Isochlortetracycline	Others	Infection
Isochlortetracycline is an inactive alkaline degradation product of the Chlortetracycline (HY-B1327A) (broad-spectrum antibiotic) .

HY-D0994

4-Methylumbelliferyl phosphate 4-MUP; MUP	Phosphatase	Others
4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant .

HY-D1208

CDP-Star

Biochemical Assay Reagents Phosphatase Others

CDP-Star is a chemiluminescent substrate for alkaline phosphatase. CDP-Star can be used for enzyme-linked immunoassays .

CDP-Star	Biochemical Assay Reagents Phosphatase	Others
CDP-Star is a chemiluminescent substrate for alkaline phosphatase. CDP-Star can be used for enzyme-linked immunoassays .

HY-B2203

Calcium glycerophosphate	Phosphatase	Metabolic Disease
Calcium glycerophosphate is an inhibitor of *intestinal alkaline* phosphatase F3**. Calcium glycerophosphate is a source of calcium and phosphorus in total parenteral nutrition solutions .

HY-D1491

Fast Red Violet LB	Fluorescent Dye	Others
Fast Red Violet LB is a dye for staining tartrate resistant acid phosphatase (TRAP). Fast Red Violet LB can be used for alkaline phosphatase (ALP) activity staining .

HY-D1491A

Fast Red Violet LB Zinc chloride	Fluorescent Dye	Others
Fast Red Violet LB Zinc chloride is a stain that stains tartrate-resistant acid phosphatase (TRAP) and Fast Red Violet LB Zinc chloride can be used to stain alkaline phosphatase (ALP) activity .

HY-W127630

AMPSO	Biochemical Assay Reagents	Others
AMPSO is an alkaline transfer buffer that can be used to transfer strongly basic proteins from gels into nitrocellulose without reducing the transfer efficiency of other proteins. AMPSO can be used for Western Blot analysis, PCR amplification and many other applications .

HY-N2511

Trimyristin	Cholinesterase (ChE) Phosphatase Endogenous Metabolite	Metabolic Disease
Trimyristin, an active molluscicidal component of Myristica fragrans Houtt, significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. IC₅₀s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively .

HY-D1676

Thymolphthalein monophosphate disodium hydrate	Phosphatase	Others
Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum .

HY-W151206

Hydroxy naphthol blue disodium	Fluorescent Dye	Others
Hydroxy naphthol blue disodium, an azo dye, is a metal indicator for calcium and a colorimetric reagent for alkaline earth metal ions ( λmax = 650 nm). In the pH range between 12 and 13, the solution of the indicator is reddish pink in the presence of calcium ion and to deep blue in the presence of disodium EDTA .

HY-157139

ALP/Carbonic anhydrase-IN-1	Carbonic Anhydrase Phosphatase	Inflammation/Immunology
ALP/Carbonic anhydrase-IN-1 (Compound 1e) is a dual carbonic anhydrase (CA) and alkaline phosphatase (ALP) inhibitor. ALP/Carbonic anhydrase-IN-1 shows IC₅₀ values of 0.44 µM, 1.61 µM, 0.51 µM, and 0.107 µM for CA-II, CA-IX, CA-XII, and ALP, respectively .

HY-D0220A

Toluidine Blue (purity 36%) Toluidine Blue O (purity 36%)	Fluorescent Dye	Others
Toluidine Blue (Toluidine Blue O) purity 36% is an alkaline quinonimine dye (vivo dye) with high affinity for acidic tissue components, staining nuclei blue and polysaccharides purple. Toluidine Blue purity 36% shows heterostaining properties for mast cells, mucins and chondrocytes. Toluidine Blue purity 36% can stain different components of plant tissues and cells in different colours. Toluidine Blue purity 36% is also used as a diagnostic aid to identify malignant lesions, such as cancer .

HY-112832

Lumigen APS-5

Phosphatase Infection

Lumigen APS-5 is a substrate of alkaline phosphatase (ALP). Lumigen APS-5 can be used to assess the activity of alkaline phosphatase (ALP) .

Lumigen APS-5	Phosphatase	Infection
Lumigen APS-5 is a substrate of alkaline phosphatase (ALP). Lumigen APS-5 can be used to assess the activity of alkaline phosphatase (ALP) .

HY-N8917

(3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane	Phosphatase	Metabolic Disease
(3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane is a homoisoflavonoid. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane increases the level of alkaline phosphatase (ALP) activity. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane promotes mesenchymal stem cells (MSCs) osteogenesis, but cannot enhance MSCs proliferation. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane can be used for osteoporosis research .

HY-B1194

Tetramisole hydrochloride (±)-Tetramisole hydrochloride; DL-Tetramisole hydrochloride; R-829	Parasite Phosphatase Antibiotic	Infection
Tetramisole hydrochloride inhibits alkaline phosphatase and is a highly pure antiparasitic agent.

HY-19695

(-)-p-Bromotetramisole oxalate 1 Publications Verification L-p-Bromotetramisole oxalate; 6-Bromolevamisole oxalate	Phosphatase	Cancer
(-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor.

HY-121932

Naphthol AS-BR

Phosphatase Others

Naphthol AS-BR is a substrate for the histochemical demonstration of acid and alkaline phosphatase .

Naphthol AS-BR	Phosphatase	Others
Naphthol AS-BR is a substrate for the histochemical demonstration of acid and alkaline phosphatase .

HY-W250315

Polypectate sodium pectate sodium	Others	Others
Polypectate sodium is a major component of cell wall polysaccharides (pectins) and is used as a carbon source and inducer of polygalacturonase. Polypectate sodium can also be used to evaluate alkaline active and alkaline stable pectate lyases from Streptomyces spp. and to study the optimization of polygalacturonase production from Xanthophyllum spp. and reaction conditions .

HY-15906

AMPPD

Lumi-Phos Plus; Lumigen PPD; PPD
Phosphatase Others

AMPPD, a 1,2-dioxo-cyclohexane derivative, is a biochemistry ultrasensitive alkaline phosphatase substrate.
HY-W008385

H-HoArg-OH

Endogenous Metabolite Metabolic Disease

H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.

AMPPD Lumi-Phos Plus; Lumigen PPD; PPD	Phosphatase	Others
AMPPD, a 1,2-dioxo-cyclohexane derivative, is a biochemistry ultrasensitive alkaline phosphatase substrate.

H-HoArg-OH	Endogenous Metabolite	Metabolic Disease
H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.

HY-D0852

Sodium orthovanadate 5 Publications Verification	Phosphatase	Cancer
Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue.

HY-15928

PNPP disodium 1 Publications Verification Para-nitrophenyl phosphate disodium	Fluorescent Dye	Others
PNPP (Para-nitrophenyl phosphate) disodium is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays.

HY-163408

ALP-IN-1

Phosphatase Others

ALP-IN-1 (Compound 7e) is an alkaline phosphatase (ALP) inhibitor (IC₅₀ = 0.308 µM) .

ALP-IN-1	Phosphatase	Others
ALP-IN-1 (Compound 7e) is an alkaline phosphatase (ALP) inhibitor (IC₅₀ = 0.308 µM) .

HY-130767

Naphthol AS-TR phosphate	Biochemical Assay Reagents	Others
Naphthol AS-TR Phosphate is a water-soluble dye commonly used as an enzyme substrate in various biochemical assays to detect alkaline phosphatase activity. Naphthol AS-TR Phosphate has unique chemical properties that allow it to be hydrolyzed by alkaline phosphatase to form a colored product that can be detected spectrophotometrically. This makes it a useful tool for monitoring enzyme activity in biological samples such as serum or urine.

HY-W002339

3-Hydroxy-2-methylpyridine

DNA/RNA Synthesis Others

3-Hydroxy-2-methylpyridine, isolated from alkaline extracts of cocoa, is used in the synthesis of pyrimidine .

3-Hydroxy-2-methylpyridine	DNA/RNA Synthesis	Others
3-Hydroxy-2-methylpyridine, isolated from alkaline extracts of cocoa, is used in the synthesis of pyrimidine .

HY-156752

Cyclosiversioside F 16,25-diacetate	Others	Others
Cyclosiversioside F 16,25-diacetate (Compound 6), a glycoside, is an alkaline hydrolysis product of Acetyl Derivative (Compound 2) .

HY-130767A

Naphthol AS-TR phosphate disodium	Biochemical Assay Reagents	Cancer
Naphthol AS-TR Phosphate disodium is a water-soluble dye commonly used as an enzymatic substrate in various biochemical assays to detect alkaline phosphatase activity. Naphthol AS-TR Phosphate disodium has unique chemical properties that allow it to be hydrolyzed by alkaline phosphatase, forming a colored product that can be detected spectrophotometrically. This makes it a useful tool for monitoring enzyme activity in biological samples such as serum or urine.

HY-15909

BCIP BCIP p-toluidine salt; X-phosphate p-toluidine salt	Fluorescent Dye	Others
BCIP(BCIP p-toluidine salt; X-phosphate p-toluidine salt) is an artificial chromogenic substrate used for the sensitive colorimetric detection of alkaline phosphatase activity.

HY-W040295

Fast Red ITR

Others Others

Fast Red ITR is a nonlinear optical material . Fast Red ITR can be used in alkaline phosphatase histochemistry .

Fast Red ITR	Others	Others
Fast Red ITR is a nonlinear optical material . Fast Red ITR can be used in alkaline phosphatase histochemistry .

HY-139852

PLAP-IN-1	Phosphatase	Cancer
PLAP-IN-1 is a potent (IC₅₀ = 32 nM) and selective PLAP inhibitor, with no detectable inhibition of tissue non-specific alkaline phosphatase (TNAP) activity.

HY-D1520

Naphthol AS-GR phosphate disodium	Phosphatase	Others
Naphthol AS-GR phosphate disodium is substrates for acid and alkaline phosphatases. Naphthol AS-GR phosphate disodium has an intense green fluorescence used in histochemical studies .

HY-W008378

5-Methoxy-2-benzimidazolethiol	Biochemical Assay Reagents	Others
5-Methoxy-2-benzimidazolethiol is a benzimidazole. The iodimetric determination of 5-Methoxy-2-benzimidazolethiol in alkaline media is studied .

HY-N2247

Guaiacin
Guaiacin is a arylnaphthalene type lignin isolated from the barks of Machilus thunbergii SIEB. et ZUCC (Lauraceae). Guaiacin significantly increases alkaline phosphatase activity and osteoblast differentiation .

HY-D0994A

4-Methylumbelliferyl phosphate disodium 4-MUP disodium; MUP disodium	Phosphatase	Others
4-Methylumbelliferyl phosphate (4-MUP) disodium, an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate disodium is also a nerve agent simulant .

HY-117095

4-Methylumbelliferyl oleate	Fluorescent Dye	Metabolic Disease
4-Methylumbelliferyl oleate is a fluorogenic substrate for acid and alkaline lipases. 4-Methylumbelliferyl oleate is cleaved by lipases, liberating 4-Methylumbelliferyl (Ex/Em=320/450 nm) .

HY-131420

12-Methyltridecanoic acid Aseanostatin P1; Isotetradecanoic acid	Biochemical Assay Reagents	Others
12-Methyltridecanoic acid is a methylated fatty acid that has been found in milk. 12-Methyltridecanoic acid (200 μM) reduces angiogenesis and corneal opacity in alkaline or Pseudomonas aeruginosa-induced ocular mouse models.

HY-W008385S

H-HoArg-OH-d4	Isotope-Labeled Compounds	Metabolic Disease
H-HoArg-OH-d₄ is a deuterium labeled H-HoArg-OH (HY-W008385). H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.

HY-P3205

Lysyl endopeptidase, Achromobacter sp Lys-C	Others	Others
Lysyl endopeptidase, Achromobacter sp (Lys-C) catalyzes carboxyl oxygen exchange reaction. Lysyl endopeptidase has higher substrate binding affinities and higher catalytic rates at the acidic pHs than at the alkaline pHs .

HY-15925

Nitro blue tetrazolium chloride 4 Publications Verification NBT	Fluorescent Dye	Others
Nitro blue tetrazolium chloride (NBT) is a substrate for dehydrogenases; is used with the alkaline phosphatase substrate 5-Bromo-4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures .

HY-124756

SBI-425 1 Publications Verification	Phosphatase	Cardiovascular Disease
SBI-425 is an orally active and potent TNAP (*tissue-nonspecific alkaline* phosphatase) inhibitor (IC₅₀**=16 nM). SBI-425 inhibits TNAP in the vasculature, improving cardiovascular parameters and survival .

HY-141577

C12-NBD Sphinganine	Biochemical Assay Reagents	Others
C12-NBD Sphinganine is a fluorescent ceramidase substrate. C12-NBD Sphinganine can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources .

HY-128591

DIPQUO 1 Publications Verification	Phosphatase	Metabolic Disease
DIPQUO is an activator of the bone marker alkaline phosphatase (ALP), with an EC₅₀ of 6.27 μM in C2C12 cells. DIPQUO promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β .

HY-119539

Limocitrin	Phosphatase	Endocrinology Cancer
Limocitrin is a natural product that can be isolated from the buds of P. acerifolia and P. orientalis. Limocitrin suppresses estradiol-dependent proliferation of MCF7 cells weakly but estradiol-induced *AlkP (alkaline* phosphatase)** expression only marginally .

HY-Y0319B

Acetic acid potassium 99%
Acetic acid potassium 99% is a potassium salt employed to replenish electrolytes, for restoration of water-electrolyte balance. Acetic acid potassium 99% can employ in DNA and protein purification. Acetic acid potassium 99% has been used to prepare neutralizing solution for alkaline lysis of bacteria .

HY-W661499

Orellanine	Phosphatase	Cancer
Orellanine is a fungal nephrotoxin. Orellanine is also a competitive inhibitor of alkaline phosphatase. Orellanine induces cell death in proximal tubular cells and in ccRCC cells. Orellanine can be used for research of clear cell renal cell carcinoma (ccRCC) .

HY-Y1242

Choline hydroxide, 44 wt.% in water
Choline hydroxide is a Choline hydrogen oxidized derivative and a strong organic base, can be used as the standard alkaline to adjust the pH of the medium. Choline is an orally active nutrient, serves as an important component of lecithin and sphingomyelin, promotes fat metabolism .

HY-N8366

Alloisoimperatorin	Phosphatase	Endocrinology Cancer
Alloisoimperatorin (Compound 5) is a phytoestrogen that can be isolated from Angelica dahurica. Alloisoimperatorin can induce alkaline phosphatase (AP) activity with an EC₅₀ of 0.8 μg/mL. Alloisoimperatorin can be used in the study of hormone-dependent cancers and the alleviation of menopausal symptoms .

HY-B0324A

Crystal Violet Maximum Cited Publications 32 Publications Verification Basic Violet 3; Gentian Violet; Methyl Violet 10B	Fluorescent Dye Influenza Virus Bacterial	Infection
Crystal Violet, also known as Gentian violet, methyl violet 10B, is a triphenyl-methane, an alkaline dye that binds to DNA in the nucleus of a cell, staining it a deep purple. It is often used for Gram staining to classify bacteria, or for cell or histological staining[1].

Cat. No.	Product Name	Type

HY-D0994

4-Methylumbelliferyl phosphate 4-MUP; MUP	Chromogenic Substrates
4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant .

HY-D1208

CDP-Star

Chromogenic Substrates

CDP-Star is a chemiluminescent substrate for alkaline phosphatase. CDP-Star can be used for enzyme-linked immunoassays .

HY-D1491

Fast Red Violet LB	Dyes
Fast Red Violet LB is a dye for staining tartrate resistant acid phosphatase (TRAP). Fast Red Violet LB can be used for alkaline phosphatase (ALP) activity staining .

HY-149835

TTX-P	Fluorescent Dyes/Probes
TTX-P is a fluorescent probe. TTX-P responds in situ to the overexpressed alkaline phosphatase (ALP) in liver, imaging of diabetic liver injury in the near-infrared second-window (NIR-II) region .

HY-D1676

Thymolphthalein monophosphate disodium hydrate

Fluorescent Dyes/Probes

Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum .

HY-D0220A

Toluidine Blue (purity 36%)

Toluidine Blue O (purity 36%)

Dyes

Toluidine Blue (Toluidine Blue O) purity 36% is an alkaline quinonimine dye (vivo dye) with high affinity for acidic tissue components, staining nuclei blue and polysaccharides purple. Toluidine Blue purity 36% shows heterostaining properties for mast cells, mucins and chondrocytes. Toluidine Blue purity 36% can stain different components of plant tissues and cells in different colours. Toluidine Blue purity 36% is also used as a diagnostic aid to identify malignant lesions, such as cancer .

HY-15928

PNPP disodium 1 Publications Verification Para-nitrophenyl phosphate disodium	Chromogenic Substrates
PNPP (Para-nitrophenyl phosphate) disodium is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays.

HY-15909

BCIP BCIP p-toluidine salt; X-phosphate p-toluidine salt	Chromogenic Substrates
BCIP(BCIP p-toluidine salt; X-phosphate p-toluidine salt) is an artificial chromogenic substrate used for the sensitive colorimetric detection of alkaline phosphatase activity.

HY-D1520

Naphthol AS-GR phosphate disodium	Fluorescent Dyes/Probes
Naphthol AS-GR phosphate disodium is substrates for acid and alkaline phosphatases. Naphthol AS-GR phosphate disodium has an intense green fluorescence used in histochemical studies .

HY-D0994A

4-Methylumbelliferyl phosphate disodium 4-MUP disodium; MUP disodium	Chromogenic Substrates
4-Methylumbelliferyl phosphate (4-MUP) disodium, an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate disodium is also a nerve agent simulant .

HY-15925

Nitro blue tetrazolium chloride 4 Publications Verification NBT	Chromogenic Substrates
Nitro blue tetrazolium chloride (NBT) is a substrate for dehydrogenases; is used with the alkaline phosphatase substrate 5-Bromo-4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures .

HY-141577

C12-NBD Sphinganine	Dyes
C12-NBD Sphinganine is a fluorescent ceramidase substrate. C12-NBD Sphinganine can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources .

HY-B0324A

Crystal Violet Maximum Cited Publications 32 Publications Verification Basic Violet 3; Gentian Violet; Methyl Violet 10B	Dyes
Crystal Violet, also known as Gentian violet, methyl violet 10B, is a triphenyl-methane, an alkaline dye that binds to DNA in the nucleus of a cell, staining it a deep purple. It is often used for Gram staining to classify bacteria, or for cell or histological staining[1].

HY-15931

TMB-PS TMBZ-PS	Chromogenic Substrates
TMB-PS(102062-36-2) is N-(3-sulfopropyl)-3,3',5,5'-tetramenthylbenzidine sodium salt; White - pale yellow crystalline powder, soluble in water, can be used under neutral, acidic and alkaline conditions.

HY-D0914

Fast Green FCF

FD&C Green No. 3; Food green 3; C.I. 42053

Dyes

Fast Green FCF is a sea green triarylmethane food dye, with absorption maximum ranging from 622 to 626 nm. Fast Green FCF is widely used as a staining agent like quantitative stain for histones at alkaline pH after acid extraction of DNA, and as a protein stain in electrophoresis. Fast Green FCF is carcinogenic and acts as a presynaptic locus by inhibiting the release of neurotransmitters in the nervous system .

HY-150086

Copper Fluor-4 CF4	Dyes
Copper Fluor-4 (CF4) is a Cu ⁺-specific fluorescent probe based on a rhodol dye scaffold. Copper Fluor-4 has high copper selectivity, particularly over zinc and iron, as well as abundant cellular alkali and alkaline earth metals. Copper Fluor-4 is stable in a physiologically relevant pH regime between 6 and 8 (Ex: 488 nm) .

HY-W010947

4-Methylumbelliferyl palmitate

Fluorescent Dyes/Probes

4-Methylumbelliferyl palmitate is an excellent fluorophore for measuring acid lipase in human leukocytes. Acidity and solvent have important influence on its fluorescence. 4-Methylumbelliferyl palmitate exists mainly as neutral molecular form which can be produced strong fluorescence at 445 nm in near neutral aqueous solutions, and exist mainly as anion form which can be produced stronger fluorescence at 445 nm in weak alkaline solutions .

Cat. No.	Product Name	Type

HY-19695

(-)-p-Bromotetramisole oxalate 1 Publications Verification L-p-Bromotetramisole oxalate; 6-Bromolevamisole oxalate	Biochemical Assay Reagents
(-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor.

HY-15906

AMPPD

Lumi-Phos Plus; Lumigen PPD; PPD
Enzyme Substrates

AMPPD, a 1,2-dioxo-cyclohexane derivative, is a biochemistry ultrasensitive alkaline phosphatase substrate.
HY-D1208

CDP-Star

Chromogenic Substrates

CDP-Star is a chemiluminescent substrate for alkaline phosphatase. CDP-Star can be used for enzyme-linked immunoassays .

HY-W127630

AMPSO	Biochemical Assay Reagents
AMPSO is an alkaline transfer buffer that can be used to transfer strongly basic proteins from gels into nitrocellulose without reducing the transfer efficiency of other proteins. AMPSO can be used for Western Blot analysis, PCR amplification and many other applications .

HY-112832

Lumigen APS-5

Enzyme Substrates

Lumigen APS-5 is a substrate of alkaline phosphatase (ALP). Lumigen APS-5 can be used to assess the activity of alkaline phosphatase (ALP) .

HY-D0852

Sodium orthovanadate 5 Publications Verification	Biochemical Assay Reagents
Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue.

HY-W342700

PIPPS

Buffer Reagents

PIPPS is a kind of buffer commonly used in biological and biochemical research to maintain the acidity and alkalinity (pH value) of solutions .

HY-130767

Naphthol AS-TR phosphate

Biochemical Assay Reagents

Naphthol AS-TR Phosphate is a water-soluble dye commonly used as an enzyme substrate in various biochemical assays to detect alkaline phosphatase activity. Naphthol AS-TR Phosphate has unique chemical properties that allow it to be hydrolyzed by alkaline phosphatase to form a colored product that can be detected spectrophotometrically. This makes it a useful tool for monitoring enzyme activity in biological samples such as serum or urine.

HY-131420

12-Methyltridecanoic acid Aseanostatin P1; Isotetradecanoic acid	Biochemical Assay Reagents
12-Methyltridecanoic acid is a methylated fatty acid that has been found in milk. 12-Methyltridecanoic acid (200 μM) reduces angiogenesis and corneal opacity in alkaline or Pseudomonas aeruginosa-induced ocular mouse models.

HY-W579346

POPSO sesquisodium	Buffer Reagents
POPSO sesquisodium is a water-soluble zwitterionic buffer. POPSO sesquisodium is commonly used in biological and biochemical studies to maintain the acidity or alkalinity (pH value) of solutions, especially within the physiological pH range of 7.0 to 8.5 .

HY-Y1269D

Ammonium chloride, for molecular biology

Salmiac, for molecular biology

Buffer Reagents

Ammonium chloride, for molecular biology (Salmiac, for molecular biology) is ammonium chloride that can be used for molecular biology research. Ammonium chloride can be used as a heteropolar compound to regulate pH value, which can cause intracellular alkalination and metabolic acidosis, thus affecting the activity of enzymes and affecting the process of biological systems. Ammonium chloride acts as an autophagy inhibitor.

HY-Y1269C

Ammonium chloride, for cell culture

5 Publications Verification

Salmiac, for cell culture

Biochemical Assay Reagents

Ammonium chloride, for cell culture (Salmiac, for cell culture) is a reagent that can be used in cell culture to provide a source of nitrogen. Ammonium chloride can be used as a heteropolar compound to regulate pH value, which can cause intracellular alkalination and metabolic acidosis, thus affecting the activity of enzymes and affecting the process of biological systems. Ammonium chloride acts as an autophagy inhibitor.

HY-W251598C

Sodium bicarbonate, for cell culture

Sodium hydrogen carbonate for cell culture; Soda bicarbonate for cell culture

Buffer Reagents

Sodium bicarbonate, for cell culture, an inorganic salt, is neutral to slightly alkaline. And it is susceptible to moisture and decomposition in the air. Sodium bicarbonate is widely used in food, pharmaceutical, cosmetics and other fields, the main uses include buffer, seasoning, disinfectant, pharmaceutical and proton gradient regulator. Sodium bicarbonate is also commonly used as an antacid to suppress gastrointestinal disorders, neutralize stomach acid and reduce stomach discomfort.

HY-Y1269H

Ammonium chloride, meets analytical specification of Ph. Eur. BP USP FCC

Salmiac, meets analytical specification of Ph. Eur. BP USP FCC

Buffer Reagents

Ammonium chloride, meets analytical specification of Ph. Eur. BP USP FCC (Salmiac, meets analytical specification of Ph. Eur. BP USP FCC) can be used as a heteropolar compound to regulate pH value, which can cause intracellular alkalination and metabolic acidosis, thus affecting the activity of enzymes and affecting the process of biological systems. Ammonium chloride acts as an autophagy inhibitor.

HY-Y1269I

Ammonium chloride, United States Pharmacopeia (USP) Reference Standard

Salmiac (Pharmaceutical primary standard, USP)

Biochemical Assay Reagents

Ammonium chloride United States Pharmacopeia (USP) Reference Standard (Salmiac, Pharmaceutical primary standard, USP) is a reagent that can be used in cell culture to provide a source of nitrogen. Ammonium chloride can be used as a heteropolar compound to regulate pH value, which can cause intracellular alkalination and metabolic acidosis, thus affecting the activity of enzymes and affecting the process of biological systems. Ammonium chloride acts as an autophagy inhibitor.

HY-116022A

4-Nitrophenyl phosphate disodium hexahydrate 2 Publications Verification p-Nitrophenyl phosphate disodium hexahydrate	Biochemical Assay Reagents
4-Nitrophenyl phosphate (p-nitrophenyl phosphate) disodium hexahydrate is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. 4-Nitrophenyl phosphate disodium hexahydrate is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm .

HY-103701B

L-Ascorbic acid 2-phosphate magnesium hydrate

2-Phospho-L-ascorbic acid magnesium hydrate

Biochemical Assay Reagents

L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) magnesium hydrate is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-ascorbic acid 2-phosphate magnesium hydrate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate magnesium hydrate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation .

HY-Y0756

Sodium bicarbonate

Sodium hydrogen carbonate

Biochemical Assay Reagents

Sodium bicarbonate, also known as baking soda, sodium bicarbonate, or sodium bicarbonate, is neutral to slightly alkaline. And it is susceptible to moisture and decomposition in the air. Sodium bicarbonate is widely used in food, pharmaceutical, cosmetics and other fields, the main uses include buffer, seasoning, disinfectant, pharmaceutical and proton gradient regulator. In the food industry, it is often used as a flour starter or leavening agent to make food swell up and become softer. Sodium bicarbonate is also commonly used as an antacid to suppress gastrointestinal disorders, neutralize stomach acid and reduce stomach discomfort.

Cat. No.	Product Name	Target	Research Area

HY-W007599

(S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid	Peptides	Cancer
(S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid is a polypeptide derivative, can be used to synthesis multifunctional amphiphilic peptide dendrimer, as a nonviral gene vectors, realizes the method in cancer research. (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid also involves in the synthesis of an organic substance that increases the luminescence intensity of alkaline phosphatase substrates .

HY-W141781

Cysteamine S-phosphate sodium Cystaphos sodium	Peptides	Metabolic Disease
Cysteamine S-phosphate (Cystaphos) sodium can be hydroIyzed to Cysteamine by human alkaline phosphatases. Cysteamine is an orally active agent for the research of nephropathic cystinosis and an antioxidant .

HY-P4835

pTH (2-34) (human)	Peptides	Others
pTH (2-34) (human) (80 μg/kg) slightly increases serum osteocalcin levels and alkaline phosphatase activity of bone extract (markers of bone formation) in mice. pTH (2-34) is not as effective as pTH (1-34) .

HY-P5457

BMP-2 Epitope (73-92)	Peptides	Others
BMP-2 Epitope (73-92) is a biological active peptide. (This is amino acids 73 to 92 fragment of bone morphogenetic protein (BMP) knuckle epitope. It is a member of transforming growth factor beta (TGF-b). This peptide fragment is able to raise alkaline phosphate activity in murine multipotent mesenchymal cells.)

HY-P4582

Suc-Phe-Ala-Ala-Phe-pNA Suc-FAAF-pNA	Peptides	Others
Suc-Phe-Ala-Ala-Phe-pNA (Suc-FAAF-pNA) is a synthetic polypeptide that can serve as a substrate for the protease from Aeribacillus pallidus VP3 (SPVP), the serine alkaline protease from Caldicoprobacter guelmensis (SAPCG) strain D2C22 ^T, the alcalase ultra 2.5 L and the thermolsyin type X .

HY-P4823

pTH (1-37) (human)	Thyroid Hormone Receptor	Metabolic Disease
pTH (1-37) (human) is a fragment of parathyroid hormone (PTH). pTH (1-37) (human) induces the cAMP formation and increases alkaline phosphatase activity. pTH (1-37) (human) increases growth, bone calcium content, and bone mineral density (BMD) in uremic animals. pTH (1-37) (human) has the potential for the research of osteoporosis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-P2818

Alkaline phosphatase, Bovine intestine 1 Publications Verification Apase	Structural Classification Natural Products Animals Classification of Application Fields Source classification Metabolic Disease Disease Research Fields	Endogenous Metabolite
Alkaline phosphatase, Bovine intestine (Apase) is a membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase can be used in molecular biology and enzyme-free analysis. Inhibition of tissue nonspecific alkaline phosphatase can block intracellular lipid accumulation .

HY-N2511

Trimyristin	Natural Products Microorganisms Classification of Application Fields Source classification Metabolic Disease Myristicaceae Plants Myristica fragrans Houtt. Endogenous metabolite Disease Research Fields	Cholinesterase (ChE) Phosphatase Endogenous Metabolite
Trimyristin, an active molluscicidal component of Myristica fragrans Houtt, significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. IC₅₀s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively .

HY-W008385

H-HoArg-OH	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Metabolic Disease Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields	Endogenous Metabolite
H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.

HY-N8917

(3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane	Dracaena cochinchinensis (Lour.) S. C. Chen Structural Classification Source classification Phenols Polyphenols Agavaceae Plants	Phosphatase
(3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane is a homoisoflavonoid. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane increases the level of alkaline phosphatase (ALP) activity. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane promotes mesenchymal stem cells (MSCs) osteogenesis, but cannot enhance MSCs proliferation. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane can be used for osteoporosis research .

HY-W250315

Polypectate sodium pectate sodium	Structural Classification Natural Products Polysaccharides Microorganisms Classification of Application Fields Other Diseases Disease Research Fields Saccharides	Others
Polypectate sodium is a major component of cell wall polysaccharides (pectins) and is used as a carbon source and inducer of polygalacturonase. Polypectate sodium can also be used to evaluate alkaline active and alkaline stable pectate lyases from Streptomyces spp. and to study the optimization of polygalacturonase production from Xanthophyllum spp. and reaction conditions .

HY-W002339

3-Hydroxy-2-methylpyridine	Alkaloids other families Classification of Application Fields Leguminosae Source classification Other Diseases Pyridine Alkaloids Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Plants Disease Research Fields	DNA/RNA Synthesis
3-Hydroxy-2-methylpyridine, isolated from alkaline extracts of cocoa, is used in the synthesis of pyrimidine .

HY-119539

Limocitrin	Structural Classification Flavonols Flavonoids Source classification Plants Platanaceae Platanus orientalis L.	Phosphatase
Limocitrin is a natural product that can be isolated from the buds of P. acerifolia and P. orientalis. Limocitrin suppresses estradiol-dependent proliferation of MCF7 cells weakly but estradiol-induced *AlkP (alkaline* phosphatase)** expression only marginally .

HY-W661499

Orellanine	Structural Classification Natural Products Microorganisms Source classification	Phosphatase
Orellanine is a fungal nephrotoxin. Orellanine is also a competitive inhibitor of alkaline phosphatase. Orellanine induces cell death in proximal tubular cells and in ccRCC cells. Orellanine can be used for research of clear cell renal cell carcinoma (ccRCC) .

HY-N8366

Alloisoimperatorin	Structural Classification Source classification Coumarins Phenylpropanoids Plants Umbelliferae Helogyne apaloidea Nutt.	Phosphatase
Alloisoimperatorin (Compound 5) is a phytoestrogen that can be isolated from Angelica dahurica. Alloisoimperatorin can induce alkaline phosphatase (AP) activity with an EC₅₀ of 0.8 μg/mL. Alloisoimperatorin can be used in the study of hormone-dependent cancers and the alleviation of menopausal symptoms .

HY-N6663

3-Carene	Other Monoterpenes other families Classification of Application Fields Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields	COX
3-Carene is a bicyclic monoterpene in essential oils extracted from pine trees. 3-Carene inhibits nociceptive stimulus-induced inflammatory infiltrates and COX-2 overexpression, and with antinociceptive effect. 3-Carene stimulates the activity and expression of alkaline phosphatase that is an early phase marker of osteoblastic differentiation .

HY-N7427

2-(2',3',4'-Trihydroxybutyl)quinoxaline	Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-(2',3',4'-Trihydroxybutyl)quinoxaline is a food metabolite. 2-(2',3',4'-Trihydroxybutyl)quinoxaline can be formed from homoglucans .

HY-133108

Azadirachtin B	Infection Structural Classification Natural Products other families Classification of Application Fields Source classification Metabolic Disease Plants Inflammation/Immunology Disease Research Fields Biological Pesticide Research Agricultural Research	EBV Parasite Phosphatase Influenza Virus
Azadirachtin B is an limonoid isolated from seed kernels of Azadirachta indica. Azadirachtin B increases alkaline phosphatase (ALP) activity and stimulates osteoblast differentiation. Azadirachtin B is active against the Epstein-Barr virus early antigen (EBV-EA). Azadirachtin B has insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral and osteogenic properties .

HY-N4119

Neoeriocitrin	Flavonoids other families Flavonones Source classification Phenols Polyphenols Plants	Cholinesterase (ChE)
Neoeriocitrin, isolated from Drynaria Rhizome, shows activity on proliferation and osteogenic differentiation in MC3T3-E1. Neoeriocitrin is a potent acetylcholinesterase (AChE) inhibitor .

HY-103701

L-Ascorbic acid 2-phosphate 2-Phospho-L-ascorbic acid	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Phosphatase Reactive Oxygen Species Endogenous Metabolite
L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) is a long-acting vitamin C derivative that can stimulate collagen formation and expression . L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation .

HY-103701B

L-Ascorbic acid 2-phosphate magnesium hydrate 2-Phospho-L-ascorbic acid magnesium hydrate	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Phosphatase Reactive Oxygen Species Endogenous Metabolite
L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) magnesium hydrate is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-ascorbic acid 2-phosphate magnesium hydrate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate magnesium hydrate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation .

HY-107837

L-Ascorbic acid 2-phosphate trisodium 1 Publications Verification 2-Phospho-L-ascorbic acid trisodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Phosphatase Reactive Oxygen Species Endogenous Metabolite
L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression . L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation .

HY-103701A

L-Ascorbic acid 2-phosphate magnesium 1 Publications Verification 2-Phospho-L-ascorbic acid magnesium	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Phosphatase Reactive Oxygen Species Endogenous Metabolite
L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression . L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation .

HY-N0123

Aloin Maximum Cited Publications 7 Publications Verification Aloin-A; Barbaloin-A	Quinones Structural Classification Liliaceae Classification of Application Fields Anthraquinones Source classification Phenols Polyphenols Aloe vera (L.) Burm. f. Plants Disease Research Fields Cancer	Others
Aloin (Aloin-A; Barbaloin-A) is a natural anti-tumor anthraquinone glycoside with iron chelating activity. Aloin induces the differentiation of MC3T3-E1 cells into osteoblasts through MAPK-mediated Wnt and Bmp signaling pathways. Alkaline phosphatase (ALP) is an early marker of osteoblast differentiation, and the activity of ALP is also enhanced by Aloin. Aloin also reduces brain edema, reduces blood-brain barrier disruption and improves cortical impact injuries. Aloin is used in research into osteoporosis and traumatic brain injury (TBI) .

Species:	Human (9) Mouse (4) Rat (2) Cynomolgus (1)
Tag:	His (14) Avi (1) Fc (2)
Source:	HEK293 (15) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P700950

	Alkaline Phosphatase/ALPG Protein, Mouse (HEK293, His) alkaline Phosphatase; alkaline phosphatase, placental-like; EAP; Alpg; Akp5; Alppl2	Mouse	HEK293
	Alkaline Phosphatase/ALPG Proteinas, an enzyme, effectively hydrolyzes various phosphate compounds. Alkaline Phosphatase/ALPG Protein, Mouse (HEK293, His) is the recombinant mouse-derived Alkaline Phosphatase/ALPG protein, expressed by HEK293, with C-His labeled tag. The total length of Alkaline Phosphatase/ALPG Protein, Mouse (HEK293, His) is 484 a.a., with molecular weight of 55-70 kDa.

HY-P700952

	Alkaline Phosphatase/ALPG Protein, Human (HEK293, His) alkaline Phosphatase; ALP-1; alkaline phosphatase, placental-like; GCAP; PLAP-like; ALPG; ALPPL; ALPPL2	Human	HEK293
	The Alkaline Phosphatase/ALPG protein, an enzyme, hydrolyzes phosphate compounds, breaking down various molecules. It acts as an alkaline phosphatase, cleaving phosphate esters and rendering molecules inactive. This versatile enzyme is vital in processes like bone mineralization, cellular signaling, and metabolism. Alkaline Phosphatase/ALPG Protein, Human (HEK293, His) is the recombinant human-derived Alkaline Phosphatase/ALPG protein, expressed by HEK293, with C-His labeled tag. The total length of Alkaline Phosphatase/ALPG Protein, Human (HEK293, His) is 484 a.a., with molecular weight of 58-68 kDa.

HY-P702581

Alkaline Phosphatase/ALPG Protein, Rat (HEK293, His)

alkaline Phosphatase; ALP-1; alkaline phosphatase, placental-like; GCAP; PLAP-like; ALPG; ALPPL; ALPPL2
Rat HEK293

HY-P72822

	ALPI Protein, Human (HEK293, His) Intestinal-type alkaline phosphatase; IAP; ALPI; alkaline Phosphatase	Human	HEK293
	ALPI Proteinas, an alkaline phosphatase, effectively hydrolyzes diverse phosphate compounds. ALPI Protein, Human (HEK293, His) is the recombinant human-derived ALPI protein, expressed by HEK293 , with C-His labeled tag. The total length of ALPI Protein, Human (HEK293, His) is 484 a.a., with molecular weight of ~70-80 kDa.

HY-P72821

	ALPI Protein, Human (HEK293, Fc) Intestinal-type alkaline phosphatase; IAP; ALPI; alkaline Phosphatase	Human	HEK293
	ALPI Proteinas, an alkaline phosphatase, effectively hydrolyzes diverse phosphate compounds. ALPI Protein, Human (HEK293, Fc) is the recombinant human-derived ALPI protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ALPI Protein, Human (HEK293, Fc) is 503 a.a., with molecular weight of 90-95 kDa.

HY-P74415

	Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, His) alkaline phosphatase; AP-TNAP; TNSALP; ALPL	Mouse	HEK293
	Alkaline Phosphatase/ALPL Protein is a preproprotein that is proteolytically cleaved to yield a signal peptide and a proproptein that is subsequently processed to generate the active mature peptide. ALPL is also a membrane-bound glycosylated enzyme that catalyzes the hydrolysis of phosphate esters at alkaline pH. Mice that lack ALPL show symptoms of osteomalacia, softening of the bones. Moreover, ALPL stimulates mineralization mainly through modulation of the balance between inorganic phosphate (Pi) and inorganic pyrophosphate (PPi) and also has a role in cardiovascular remodelling. Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, His) is the recombinant mouse-derived Alkaline Phosphatase/ALPL protein, expressed by HEK293 , with C-His, C-8*His labeled tag. The total length of Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, His) is 502 a.a., with molecular weight of ~55 kDa.

HY-P74416

	Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, Fc) alkaline phosphatase; AP-TNAP; TNSALP; ALPL	Mouse	HEK293
	Alkaline Phosphatase/ALPL Protein is a preproprotein that is proteolytically cleaved to yield a signal peptide and a proproptein that is subsequently processed to generate the active mature peptide. ALPL is also a membrane-bound glycosylated enzyme that catalyzes the hydrolysis of phosphate esters at alkaline pH. Mice that lack ALPL show symptoms of osteomalacia, softening of the bones. Moreover, ALPL stimulates mineralization mainly through modulation of the balance between inorganic phosphate (Pi) and inorganic pyrophosphate (PPi) and also has a role in cardiovascular remodelling. Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Alkaline Phosphatase/ALPL protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, Fc) is 502 a.a., with molecular weight of ~80.3 kDa.

HY-P700395

	ALPI Protein, Rat (HEK293, His) Intestinal-type alkaline phosphatase; IAP; ALPI; alkaline Phosphatase	Rat	HEK293
	The ALPI protein, an alkaline phosphatase enzyme, hydrolyzes phosphate compounds, demonstrating enzymatic activity in breaking down different phosphate molecules. ALPI Protein, Rat (HEK293, His) is the recombinant rat-derived ALPI protein, expressed by HEK293, with N-10*His labeled tag. The total length of ALPI Protein, Rat (HEK293, His) is 491 a.a., with molecular weight of 55.9 kDa.

HY-P700949

	Alkaline Phosphatase/ALPP Protein, Cynomolgus (HEK293, His) alkaline phosphatase; PLAP-1; ALPP; PLAP	Cynomolgus	HEK293
	Alkaline Phosphatase (ALPP) is an ubiquitous membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at basic pH values. Zinc and magnesium are essential cofactors of ALPP. ALPP down-regulates the secretory activities of the intrahepatic biliary epithelium. Alkaline Phosphatase/ALPP Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Alkaline Phosphatase/ALPP protein, expressed by HEK293 , with C-His labeled tag. The total length of Alkaline Phosphatase/ALPP Protein, Cynomolgus (HEK293, His) is 483 a.a., with molecular weight of 57-67 kDa.

HY-P700394

	ALPI Protein, Human (HEK293, N-His) Intestinal-type alkaline phosphatase; IAP; ALPI; alkaline Phosphatase	Human	HEK293
	ALPI Proteinas, an alkaline phosphatase, effectively hydrolyzes diverse phosphate compounds. ALPI Protein, Human (HEK293, N-His) is the recombinant human-derived ALPI protein, expressed by HEK293, with N-10*His labeled tag. The total length of ALPI Protein, Human (HEK293, N-His) is 484 a.a., with molecular weight of 55.2 kDa.

HY-P700951

	Alkaline Phosphatase/ALPG Protein, Human (Biotinylated, HEK293, His-Avi) alkaline Phosphatase; ALP-1; alkaline phosphatase, placental-like; GCAP; PLAP-like; ALPG; ALPPL; ALPPL2	Human	HEK293
	The Alkaline Phosphatase/ALPG protein, an enzyme, hydrolyzes phosphate compounds, breaking down various molecules. It acts as an alkaline phosphatase, cleaving phosphate esters and rendering molecules inactive. This versatile enzyme is vital in processes like bone mineralization, cellular signaling, and metabolism. Alkaline Phosphatase/ALPG Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived Alkaline Phosphatase/ALPG protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of Alkaline Phosphatase/ALPG Protein, Human (Biotinylated, HEK293, His-Avi) is 484 a.a., with molecular weight of 56-70 kDa.

HY-P7487

	Alkaline Phosphatase/ALPP Protein, Human (HEK293, His) rHualkaline Phosphatase, His; ALPP; PLAP; ALP; AKP2; alkaline Phosphatase	Human	HEK293
	ALPP Protein, Human (HEK293, His) is a ubiquitous membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at basic pH values.

HY-P7880

	Alkaline Phosphatase/ALPL Protein, Human (HEK293, His) rHualkaline phosphatase, tissue-nonspecific isozyme/ALPL, His; alkaline Phosphatase; Tissue-Nonspecific Isozyme; AP-TNAP; TNSALP; alkaline Phosphatase Liver/Bone/Kidney Isozyme; ALPL	Human	HEK293
	Alkaline Phosphatase/ALPL Protein, Human (HEK 293, His) is a cell-surface homodimeric phosphohydrolase that is richly expressed in the skeleton, liver, kidney and developing teeth.

HY-P7487A

	Alkaline Phosphatase/ALPP Protein, Human (HEK293, C-His) rHualkaline Phosphatase, His; ALPP; PLAP; ALP; AKP2; alkaline Phosphatase	Human	HEK293
	Alkaline Phosphatase/ALPP Proteinas, an enzyme, effectively hydrolyzes various phosphate compounds. Alkaline Phosphatase/ALPP Protein, Human (HEK293, C-His) is the recombinant human-derived Alkaline Phosphatase/ALPP protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Alkaline Phosphatase/ALPP Protein, Human (HEK293, C-His) is 484 a.a., with molecular weight of approximately 62.5 kDa.

HY-P71692

	ALPI Protein, Human (His) alkaline phosphatase intestinal; Glycerophosphatase; IAP	Human	E. coli
	ALPI Proteinas, an alkaline phosphatase, effectively hydrolyzes diverse phosphate compounds. ALPI Protein, Human (His) is the recombinant human-derived ALPI protein, expressed by E. coli , with N-His labeled tag. The total length of ALPI Protein, Human (His) is 475 a.a., with molecular weight of ~55.5 kDa.

HY-P700653

	Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, C-His) IAP; Akp2; ALPL; APTNAP; AP-TNAP; FLJ40094; FLJ93059; HOPS; MGC161443; TNAP; TNSALP	Mouse	HEK293
	Alkaline Phosphatase/ALPL Protein, vital with phosphatase, metal ion binding, and homodimerization activities, influences BMP stimulus response. Strategically located externally on the plasma membrane, its predicted activity emphasizes cellular functions. Prominent expression in the intestine and testis, especially in duodenum adult (RPKM 2234.3) and small intestine adult (RPKM 1574.5), underscores specific roles in these contexts. Its human orthologs, implicated in inflammatory bowel disease, highlight clinical relevance. Evolutionarily conserved, Alkaline Phosphatase/ALPL shares orthologous counterparts like ALPI in several human genes. Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived Alkaline Phosphatase/ALPL protein, expressed by HEK293 , with C-His labeled tag. The total length of Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, C-His) is 481 a.a., with molecular weight of 60-70 kDa.

Cat. No.	Product Name	Chemical Structure

HY-18569S

3-Indoleacetic acid-d5 1 Publications Verification
3-Indoleacetic acid-d₅ is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-d₅ can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates[1].

HY-W008385S

H-HoArg-OH-d4

H-HoArg-OH-d₄ is a deuterium labeled H-HoArg-OH (HY-W008385). H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.

HY-W008378S

5-Methoxy-2-benzimidazolethiol-d3
5-Methoxy-2-benzimidazolethiol-d₃ is the deuterium labeled 5-Methoxy-2-benzimidazolethiol[1]. 5-Methoxy-2-benzimidazolethiol is a benzimidazole. The iodimetric determination of 5-Methoxy-2-benzimidazolethiol in alkaline media is studied[2].

HY-N2511S

Trimyristin--d15
Trimyristin--d₁₅ is the deuterium labeled Trimyristin. Trimyristin, an active molluscicidal component of Myristica fragrans Houtt, significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. IC50s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively[1].

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