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Results for "

amino-groups

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (1) ADC Linker (1) Biochemical Assay Reagents (3) DNA Stain (1) Drug-Linker Conjugates for ADC (2) Endogenous Metabolite (1) Endothelin Receptor (1) Fluorescent Dye (25) GCGR (2) GLP Receptor (3) IFNAR (1) Liposome (4) PARP (1) PROTAC Linkers (5) Somatostatin Receptor (3)
By Research Areas:	Cancer (13) Cardiovascular Disease (1) Infection (3) Metabolic Disease (6) Neurological Disease (1)
Click Chemistry:	Azide (1) Alkynes (1)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Click Chemistry

Targets Recommended: Amino Acid Derivatives EAAT

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-135414B

Cyanine5 NHS ester iodide 1 Publications Verification	Fluorescent Dye	Others
Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .

HY-D0819A

CY5-SE triethylamine salt Maximum Cited Publications 9 Publications Verification Cy5 NHS Ester triethylamine salt; Sulfo-Cyanine5 Succinimidyl Ester triethylamine salt	Fluorescent Dye	Others
Cy5-SE (Cy5 NHS Ester) triethylamine salt is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. Cy5-SE triethylamine salt is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides Ex=649 nm; Em=670 nm) .

HY-135414

Cyanine5 NHS ester chloride	Fluorescent Dye	Others
Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .

HY-D1756

ROX NHS ester, 6-isomer	Fluorescent Dye	Others
ROX NHS ester, 6-isomer is a highly fluorescent, and photostable rhodamine dye for various applications. ROX labeled oligonucleotide probes are often used in qPCR, and qPCR instruments have ROX channel. This is reactive dye for the labeling of amino-groups in peptides, proteins, and amino-oligonucleotides. Pure single isomer.

HY-149117

AF430 NHS ester	Fluorescent Dye	Others
AF430 NHS ester is an AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 430 nm and an emission wavelength of 542 nm. AF430 NHS ester can be uesd for the labeling of amino-groups in peptides, proteins, and oligonucleotides. To achieve specific coupling of dye labels and biomolecules.

HY-D1596

Cyanine 3.5 chloride Cy3.5 NHS ester chloride; Cy 3.5 chloride	Fluorescent Dye	Others
Cyanine 3.5 (Cy3.5 NHS ester) chloride is an analog of Cy3.5 fluorophore. Cyanine 3.5 chloride is a reactive, red fluorescent dye. Cyanine 3.5 chloride is used for labeling of amino-groups in peptides, proteins, and oligonucleotides. (λ_ex=591 nm, λ_em=604 nm) .

HY-D0820

CY5-YNE Sulfo-Cyanine5-alkyne	Fluorescent Dye	Others
CY5-YNE (Sulfo-Cyanine5-alkyne) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. CY5-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D0819

CY5-SE Maximum Cited Publications 9 Publications Verification Cy5 NHS Ester; Sulfo-Cyanine5 Succinimidyl Ester
Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm):649, Emission (nm): 670.

HY-D1103

SiR dye 1	Fluorescent Dye	Others
SiR dye 1 is a new silicon rhodamine-like fluorescent probe, and can be conjugated with small molecules, peptides and oligonucleotide aminogroups or proteins with antibodies .

HY-151823

8-Azido-octanoyl-OSu	ADC Linker	Others
8-Azido-octanoyl-OSu is a click chemistry reagent containing an azide group. Used as a building block to introduce 8-azidooctanoic acid (CAS 217180-76-2) fragment. This fragment is used for further modifications using Click-chemistry (CuAAC), as a protected aminogroup or is used in physico-chemical investigations .

HY-W041983

Fmoc-Cpa-OH

Amino Acid Derivatives Others

Fmoc-Cpa-OH is a compound containing both an amino group and a carboxyl group.

Fmoc-Cpa-OH	Amino Acid Derivatives	Others
Fmoc-Cpa-OH is a compound containing both an amino group and a carboxyl group.

HY-D0042

NBD-Cl 1 Publications Verification NBD chloride	Fluorescent Dye	Others
NBD-Cl is a nonfluorescent reagent which becomes highly fluorescent after reaction with thiol or amino groups .

HY-D0923

Cy3.5 NHS ester

Fluorescent Dye Others

Cy3.5 NHS ester is a reactive dye for the labeling of amino groups in peptides, proteins, and oligonucleotides .

Cy3.5 NHS ester	Fluorescent Dye	Others
Cy3.5 NHS ester is a reactive dye for the labeling of amino groups in peptides, proteins, and oligonucleotides .

HY-D0925A

Cy5.5-SE (DIPEA) 1 Publications Verification Cyanine5.5 NHS ester (DIPEA)	DNA Stain Fluorescent Dye	Others
Cy5.5-SE (Cyanine5.5 NHS ester) DIPEA is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance . Storage: protect from light.

HY-D0923A

Cy3.5 NHS ester TEA

Fluorescent Dye Others

Cy3.5 NHS ester TEA is a reactive dye for the labeling of amino groups in peptides, proteins, and oligonucleotides .
HY-148340

24RBPyBC

Others Others

24RBPyBC is a dinucleating macrocyclic ligand, it contains phenolate pyridine, bipyridine, and amino groups form dinuclear Fe(II) and Fe(III) complexes .

Cy3.5 NHS ester TEA	Fluorescent Dye	Others
Cy3.5 NHS ester TEA is a reactive dye for the labeling of amino groups in peptides, proteins, and oligonucleotides .

24RBPyBC	Others	Others
24RBPyBC is a dinucleating macrocyclic ligand, it contains phenolate pyridine, bipyridine, and amino groups form dinuclear Fe(II) and Fe(III) complexes .

HY-W018678

8-Aminooctanoic acid	Others	Metabolic Disease
8-Aminooctanoic acid is an omega-amino fatty acid that is octanoic acid which carries an amino group at position 8. 8-aminooctanoic acid has a role as a human metabolite .

HY-D0112

7-Hydroxycoumarin-4-acetic acid	Fluorescent Dye	Others
7-Hydroxycoumarin-4-acetic acid, a pH-indicator dye, is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λ_max=326 nm) .

HY-D0017

Dansyl chloride DNSCl	Fluorescent Dye	Others
Dansyl chloride is a reagent that produces stable blue or blue-green fluorescent sulfonamide adducts in the reaction of aliphatic and aromatic amines with primary amino groups, and is widely used for modified amino acids, protein sequencing and amino acid analysis .

HY-126994

*6′-Amino-D-luciferin*	Fluorescent Dye	Others
6’-Amino-D-luciferin is a D-luciferin (HY-12591A) with its 6-position hydroxyl group substituted with an amino group. D-luciferin is the natural substrate of the enzyme luciferase (Luc) .

HY-135414A

Cyanine5 NHS ester bromide	Fluorescent Dye	Others
Cyanine5 NHS ester bromide is a active compound, can be used to label amino groups in peptides, proteins, and oligonucleotides. Cyanine5 NHS ester bromide is a cyanine dye, fluorescence-labeling neurotensin (8-13) via arginine residues .

HY-155500

Digoxigenin NHS ester	Others	Others
Digoxigenin NHS ester is an activated ester which readily reacts with amino groups under mild conditions, attaching the digoxigenin (HY-B1025) moiety to proteins or amino-. Digoxigenin NHS ester can be used to label proteins and oligonucleotides .

HY-21088

*3-Amino-2-piperidinone* Cyclo-ornithine	Endogenous Metabolite	Metabolic Disease
3-aminopiperidine-2-one is a metabolite from all living organisms. 3-aminopiperidine-2-one is a delta-lactam that is 2-piperidone substituted at position 3 by an amino group.

HY-D1085

AMCA-X SE	Fluorescent Dye	Others
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .

HY-156386

SCO-PEG3-COOH	PROTAC Linkers	Cancer
SCO-PEG3-COOH is a PROTAC linker and belongs to the PEG class. SCO-PEG3-COOH contains SCO and COOH that can be covalently combined with amino groups respectively. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.

HY-156387

SCO-PEG4-COOH	PROTAC Linkers	Cancer
SCO-PEG4-COOH is a PROTAC linker and belongs to the PEG class. SCO-PEG4-COOH contains SCO and COOH that can be covalently combined with amino groups, respectively. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.

HY-156388

SCO-PEG8-COOH	PROTAC Linkers	Cancer
SCO-PEG8-COOH is a PROTAC linker and belongs to the PEG class. SCO-PEG8-COOH contains SCO and COOH that can be covalently combined with amino groups, respectively. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.

HY-W097018

Iomeprol intermediate-1	Biochemical Assay Reagents	Others
Iomeprol intermediate-1 (compound 5) is an iodinated polysaccharide compound used in the synthesis of contrast agents. The amino group of Iomeprol intermediate-1 can be coupled to the carboxyl group of the D-glucuronide subunit of non-animal stable hyaluronic acid (NASHA), providing a water-soluble, radiopaque moiety .

HY-130695

*N-(Amino-PEG5)-N-bis(PEG4-acid)*	PROTAC Linkers	Cancer
N-(Amino-PEG5)-N-bis(PEG4-acid) is a PEG-based PROTAC linker used in the synthesis of PROTACs. N-(Amino-PEG5)-N-bis(PEG4-acid) contains an amino group with two terminal carboxylic acids .

HY-156385

SCO-PEG8-NHS	PROTAC Linkers	Cancer
SCO-PEG8-NHS SCO is a PROTAC linker and belongs to the PEG class. SCO-PEG8-NHS SCO contains SCO and NHS esters that can be covalently bound to amino groups, respectively. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.

HY-D2160

AF 647 carboxylic acid	Fluorescent Dye	Others
AF 647 carboxylic acid is a derivative of the far-infrared dye AF 647. AF 647 is often used as a replacement for Cy5 dye. The maximum excitation wavelength is 648 nm and the maximum emission wavelength is 671 nm. AF 647 carboxylic acid has a carboxylic acid group and can be coupled to biomolecules with amino groups to achieve dye labeling.

HY-133513

(±)-H3RESCA-TFP (±)-H3L28	Others	Cancer
(±)-H3RESCA-TFP ((±)-H3L28) is a tetrafluorophenyl ester derivative of restrained complexing agent (RESCA). (±)-H3RESCA-TFP can be used to conjugate the chelator with a biomolecule via amine coupling (e.g., N terminus and/or the ε-amino groups of lysine) .

HY-D2163

AF 430 amine	Fluorescent Dye	Others
AF 430 amine is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 430 nm and an emission wavelength of 542 nm. AF 430 amine can form covalent bonds through a condensation reaction between amino groups and molecules containing carboxyl groups. To achieve specific coupling of dye labels and biomolecules.

HY-D2154

AF 430 carboxylic acid	Fluorescent Dye	Others
AF 430 carboxylic acid is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 430 nm and an emission wavelength of 542 nm. AF 430 carboxylic acid can form covalent bonds through a condensation reaction between carboxylic acid groups and molecules containing amino groups. To achieve specific coupling of dye labels and biomolecules.

HY-D2162

AF 594 carboxylic acid	Fluorescent Dye	Others
AF 594 carboxylic acid is a carboxyl derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 carboxylic acid can form stable covalent bonds through the reaction of carboxylic acid groups with molecules with amino groups.

HY-P4146

Survodutide BI 456906	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .

HY-P4146A

Survodutide TFA BI 456906 TFA	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .

HY-P99735

Mipeginterferon alfa-2b	IFNAR	Infection
Mipeginterferon alfa-2b is an interferon alpha-2b (IFNA2b) analogue, with an average number of 5 substituted among 11 amino groups (one N-terminal and 10 lysine N6). Mipeginterferon alfa-2b has the relative molecular mass of 40 kDa .

HY-141147

*7-O-(Amino-PEG4)-paclitaxel*	Drug-Linker Conjugates for ADC	Cancer
7-O-(Amino-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Amino-PEG4)-paclitaxel can be used in the synthesis of Antibody-Drug Conjugates (ADCs) .

HY-145442

8-Azanebularine	Others	Others
8-Azanebularine, a compound with hydrogen in place of the C6 amino group, inhibits the ADAR2 reaction at high concentrations (IC₅₀=15 mM). 8-Azanebularine is incorporated into an RNA structure recognized by human ADAR2 results in high-affinity binding (K_D=2 nM). 8-Azanebularine can be used for the research of ADAR-catalyzed RNA-editing reaction .

HY-P1883

Bacterial Sortase Substrate III, Abz/DNP	Fluorescent Dye	Infection
Bacterial Sortase Substrate III, Abz/DNP is an internally quenched fluorescent peptide substrate. Staphylococcus aureus transpeptidase sortase A (SrtA) reacts with its native substrate Bacterial Sortase Substrate III, Abz/DNP, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this substrate can be monitored at Ex/Em=320 nm/420 nm.

HY-P1883A

Bacterial Sortase Substrate III, Abz/DNP TFA	Fluorescent Dye	Infection
Bacterial Sortase Substrate III, Abz/DNP TFA is an internally quenched fluorescent peptide substrate. Staphylococcus aureus transpeptidase sortase A (SrtA) reacts with its native substrate Bacterial Sortase Substrate III, Abz/DNP, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this substrate can be monitored at Ex/Em=320 nm/420 nm.

HY-141148

7-O-(Cbz-N-amido-PEG4)-paclitaxel	Drug-Linker Conjugates for ADC	Cancer
7-O-(Cbz-N-amido-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Cbz-N-amido-PEG4)-paclitaxel can be used in the synthesis of Antibody-Drug Conjugates (ADCs) .

HY-N7426

3-Deoxyglucosone 3-Deoxy-D-glucosone	GLP Receptor	Metabolic Disease
3-Deoxyglucosone (3-Deoxy-D-glucosone) is a reactive intermediate of the Maillard reaction and the polyol pathway. 3-Deoxyglucosone rapidly reacts with protein amino groups to form advanced glycation end products (AGEs), such as imidazolone, it is the most specific AGE for 3-DG. 3-Deoxyglucosone synergizes with low glucose to potentiate GLP-1 secretion and is considered as a biomarker for diabetes .

HY-155887

DSPE-PEG-Amine, MW 3400 ammonium DSPE-PEG-NH2, MW 3400 ammonium	Liposome	Others
DSPE-PEG-Amine, MW 3400 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 3400 (ammonium) can be converted to aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-155908

DSPE-PEG-Amine, MW 10000 ammonium DSPE-PEG-NH2, MW 10000 ammonium	Liposome	Others
DSPE-PEG-Amine, MW 10000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 10000 (ammonium) can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-155907

DSPE-PEG-Amine, MW 5000 ammonium DSPE-PEG-NH2, MW 5000 ammonium	Liposome	Others
DSPE-PEG-Amine, MW 5000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG-Amine, MW 5000 (ammonium) amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-W440823A

DSPE-PEG-Amine, MW 1000 ammonium DSPE-PEG-NH2, MW 1000 ammonium	Liposome	Others
DSPE-PEG-Amine, MW 1000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 1000 (ammonium) can be converted to an aromatic aldehyde, which reacts with an acetone-protected aromatic hydrazine on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-P2434

AP102	Somatostatin Receptor	Neurological Disease Metabolic Disease Cancer
AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC₅₀: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .

HY-D1886

Vari Fluor 647 SE	Fluorescent Dye	Others
Vari Fluor 647 SE is a fluorescent dye, SE stands for "succinimidyl ester". Vari Fluor 647 SE belongs to the Vari Fluor family of labeling reagents used in cell and molecular biology research. Vari Fluor 647 SE can react with an amino group to form a covalent bond, thereby introducing Vari Fluor 647 dye into the target molecule or cell. Vari Fluor 647 SE is a reactive dye that produces a fluorescent signal after binding to a target molecule or cell.

Cat. No.	Product Name	Type

HY-135414B

Cyanine5 NHS ester iodide 1 Publications Verification	Fluorescent Dyes/Probes
Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .

HY-D0819A

CY5-SE triethylamine salt Maximum Cited Publications 9 Publications Verification Cy5 NHS Ester triethylamine salt; Sulfo-Cyanine5 Succinimidyl Ester triethylamine salt	Fluorescent Dyes/Probes
Cy5-SE (Cy5 NHS Ester) triethylamine salt is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. Cy5-SE triethylamine salt is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides Ex=649 nm; Em=670 nm) .

HY-135414

Cyanine5 NHS ester chloride	Fluorescent Dyes/Probes
Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .

HY-D1756

ROX NHS ester, 6-isomer	Fluorescent Dyes/Probes
ROX NHS ester, 6-isomer is a highly fluorescent, and photostable rhodamine dye for various applications. ROX labeled oligonucleotide probes are often used in qPCR, and qPCR instruments have ROX channel. This is reactive dye for the labeling of amino-groups in peptides, proteins, and amino-oligonucleotides. Pure single isomer.

HY-149117

AF430 NHS ester	Fluorescent Dyes/Probes
AF430 NHS ester is an AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 430 nm and an emission wavelength of 542 nm. AF430 NHS ester can be uesd for the labeling of amino-groups in peptides, proteins, and oligonucleotides. To achieve specific coupling of dye labels and biomolecules.

HY-D1596

Cyanine 3.5 chloride Cy3.5 NHS ester chloride; Cy 3.5 chloride	Fluorescent Dyes/Probes
Cyanine 3.5 (Cy3.5 NHS ester) chloride is an analog of Cy3.5 fluorophore. Cyanine 3.5 chloride is a reactive, red fluorescent dye. Cyanine 3.5 chloride is used for labeling of amino-groups in peptides, proteins, and oligonucleotides. (λ_ex=591 nm, λ_em=604 nm) .

HY-D0820

CY5-YNE Sulfo-Cyanine5-alkyne	Protein Labeling
CY5-YNE (Sulfo-Cyanine5-alkyne) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. CY5-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1103

SiR dye 1	Fluorescent Dyes/Probes
SiR dye 1 is a new silicon rhodamine-like fluorescent probe, and can be conjugated with small molecules, peptides and oligonucleotide aminogroups or proteins with antibodies .

HY-D0042

NBD-Cl

1 Publications Verification

NBD chloride
Dyes

NBD-Cl is a nonfluorescent reagent which becomes highly fluorescent after reaction with thiol or amino groups .
HY-D0923

Cy3.5 NHS ester

Fluorescent Dyes/Probes

Cy3.5 NHS ester is a reactive dye for the labeling of amino groups in peptides, proteins, and oligonucleotides .
HY-D0923A

Cy3.5 NHS ester TEA

Fluorescent Dyes/Probes

Cy3.5 NHS ester TEA is a reactive dye for the labeling of amino groups in peptides, proteins, and oligonucleotides .

HY-D0112

7-Hydroxycoumarin-4-acetic acid	Fluorescent Dyes/Probes
7-Hydroxycoumarin-4-acetic acid, a pH-indicator dye, is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λ_max=326 nm) .

HY-D0017

Dansyl chloride DNSCl	Protein Labeling
Dansyl chloride is a reagent that produces stable blue or blue-green fluorescent sulfonamide adducts in the reaction of aliphatic and aromatic amines with primary amino groups, and is widely used for modified amino acids, protein sequencing and amino acid analysis .

HY-135414A

Cyanine5 NHS ester bromide	Fluorescent Dyes/Probes
Cyanine5 NHS ester bromide is a active compound, can be used to label amino groups in peptides, proteins, and oligonucleotides. Cyanine5 NHS ester bromide is a cyanine dye, fluorescence-labeling neurotensin (8-13) via arginine residues .

HY-D1085

AMCA-X SE	Fluorescent Dyes/Probes
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .

HY-D2160

AF 647 carboxylic acid	Fluorescent Dyes/Probes
AF 647 carboxylic acid is a derivative of the far-infrared dye AF 647. AF 647 is often used as a replacement for Cy5 dye. The maximum excitation wavelength is 648 nm and the maximum emission wavelength is 671 nm. AF 647 carboxylic acid has a carboxylic acid group and can be coupled to biomolecules with amino groups to achieve dye labeling.

HY-D2163

AF 430 amine	Fluorescent Dyes/Probes
AF 430 amine is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 430 nm and an emission wavelength of 542 nm. AF 430 amine can form covalent bonds through a condensation reaction between amino groups and molecules containing carboxyl groups. To achieve specific coupling of dye labels and biomolecules.

HY-D2154

AF 430 carboxylic acid	Fluorescent Dyes/Probes
AF 430 carboxylic acid is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 430 nm and an emission wavelength of 542 nm. AF 430 carboxylic acid can form covalent bonds through a condensation reaction between carboxylic acid groups and molecules containing amino groups. To achieve specific coupling of dye labels and biomolecules.

HY-D2162

AF 594 carboxylic acid	Fluorescent Dyes/Probes
AF 594 carboxylic acid is a carboxyl derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 carboxylic acid can form stable covalent bonds through the reaction of carboxylic acid groups with molecules with amino groups.

HY-D1886

Vari Fluor 647 SE

Fluorescent Dyes/Probes

Vari Fluor 647 SE is a fluorescent dye, SE stands for "succinimidyl ester". Vari Fluor 647 SE belongs to the Vari Fluor family of labeling reagents used in cell and molecular biology research. Vari Fluor 647 SE can react with an amino group to form a covalent bond, thereby introducing Vari Fluor 647 dye into the target molecule or cell. Vari Fluor 647 SE is a reactive dye that produces a fluorescent signal after binding to a target molecule or cell.

HY-D2169

AF 568 carboxylic acid

Fluorescent Dyes/Probes

AF 568 carboxylic acid is the non-reactive form of the orange fluorescent dye AF 568. AF 568 has a maximum emission wavelength of ~568 nm. AF 568 alkyne forms stable covalent bonds by reacting carboxylic acid groups with molecules bearing amino groups. Copper-catalyzed azide-alkyne cycloaddition (CuAAc) can occur with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-112697

Rhodamine B isothiocyanate

Dyes

Rhodamine B isothiocyanate (RBITC) is a fluorescent dye commonly used in biological imaging and labeling applications. It has an isothiocyanate functional group that can be covalently attached to amino groups on proteins and other biomolecules, making it useful for fluorescent labeling of cells and tissues. RBITC fluoresces bright orange-red under green light excitation, which makes it easy to detect and track labeled molecules in complex samples. Due to its stability and sensitivity, RBITC has been widely used in various research fields, including cell biology, immunology, and neurobiology.

Cat. No.	Product Name	Type

HY-W027592

1H-1,2,4-Triazol-3-amine

Biochemical Assay Reagents

1H-1,2,4-Triazol-3-amine consists of a triazole ring system and an amino group attached to carbon atom 3. The compound has potential applications in various fields such as medicinal chemistry, agrochemicals and material science. In medicinal chemistry, 1H-1,2,4-Triazol-3-amine is used as a starting material for the synthesis of pharmaceutical compounds such as antifungal agents, anticancer agents, and enzyme inhibitors associated with cardiovascular disease. In agrochemicals, it can be used as a raw material for the synthesis of herbicides, fungicides and insecticides. Furthermore, 1H-1,2,4-Triazol-3-amine is used as a ligand in coordination chemistry and as a precursor for the production of new functional materials such as polymers and metal-organic frameworks.

HY-155887

DSPE-PEG-Amine, MW 3400 ammonium

DSPE-PEG-NH2, MW 3400 ammonium

Drug Delivery

DSPE-PEG-Amine, MW 3400 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 3400 (ammonium) can be converted to aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-155908

DSPE-PEG-Amine, MW 10000 ammonium

DSPE-PEG-NH2, MW 10000 ammonium

Drug Delivery

DSPE-PEG-Amine, MW 10000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 10000 (ammonium) can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-155907

DSPE-PEG-Amine, MW 5000 ammonium

DSPE-PEG-NH2, MW 5000 ammonium

Drug Delivery

DSPE-PEG-Amine, MW 5000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG-Amine, MW 5000 (ammonium) amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-W440823A

DSPE-PEG-Amine, MW 1000 ammonium

DSPE-PEG-NH2, MW 1000 ammonium

Drug Delivery

DSPE-PEG-Amine, MW 1000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 1000 (ammonium) can be converted to an aromatic aldehyde, which reacts with an acetone-protected aromatic hydrazine on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

Cat. No.	Product Name	Target	Research Area

HY-W041983

Fmoc-Cpa-OH

Amino Acid Derivatives Others

Fmoc-Cpa-OH is a compound containing both an amino group and a carboxyl group.

HY-21983

O-Acetyl-N-[(1,1-dimethylethoxy)carbonyl]-L-threonine	Peptides	Others
O-Acetyl-N-[(1,1-dimethylethoxy)carbonyl]-L-threonine is a compound containing both an amino group and a carboxyl group.

HY-P4146

Survodutide BI 456906	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .

HY-P4146A

Survodutide TFA BI 456906 TFA	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .

HY-P4757

N1-Glutathionyl-spermidine disulfide

Peptides Others

N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-P1883

Bacterial Sortase Substrate III, Abz/DNP	Fluorescent Dye	Infection
Bacterial Sortase Substrate III, Abz/DNP is an internally quenched fluorescent peptide substrate. Staphylococcus aureus transpeptidase sortase A (SrtA) reacts with its native substrate Bacterial Sortase Substrate III, Abz/DNP, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this substrate can be monitored at Ex/Em=320 nm/420 nm.

HY-P1883A

Bacterial Sortase Substrate III, Abz/DNP TFA	Fluorescent Dye	Infection
Bacterial Sortase Substrate III, Abz/DNP TFA is an internally quenched fluorescent peptide substrate. Staphylococcus aureus transpeptidase sortase A (SrtA) reacts with its native substrate Bacterial Sortase Substrate III, Abz/DNP, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this substrate can be monitored at Ex/Em=320 nm/420 nm.

HY-P2434

AP102	Somatostatin Receptor	Neurological Disease Metabolic Disease Cancer
AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC₅₀: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .

HY-P5481

DABCYL-LPETG-EDANS	Peptides	Others
DABCYL-LPETG-EDANS is a biological active peptide. (This 5-amino acid peptide is a sortase substrate, C-terminal sorting signal. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Sortases are a family of Gram-positive transpeptidases responsible for anchoring surface protein virulence factors to the peptidoglycan cell wall layer. Cleavage of this FRET substrate by sortase reveals the fluorescent signal, Abs/Em = 340/490 nm.)

HY-P5362

NODAGA-LM3	Somatostatin Receptor	Cancer
NODAGA-LM3 can be labeled by ⁶⁸Ga for PET imaging. ⁶⁸Ga-NODAGA-LM3 is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas .

HY-P5362A

NODAGA-LM3 TFA	Somatostatin Receptor	Cancer
NODAGA-LM3 TFA can be labeled by ⁶⁸Ga for PET imaging. ⁶⁸Ga-NODAGA-LM3 TFA is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas .

HY-105168

TAK 044	Endothelin Receptor	Cardiovascular Disease
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .

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