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Results for "

anaesthetic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Ferroptosis (2) GABA Receptor (2) Isotope-Labeled Compounds (4) NF-κB (3) NOD-like Receptor (NLR) (3) Potassium Channel (3) Sodium Channel (9)
By Research Areas:	Cancer (4) Cardiovascular Disease (4) Inflammation/Immunology (2) Neurological Disease (16)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-108068

Alphadolone acetate

Alfadolone acetate; GR 2/1574
Others Neurological Disease

Alphadolone acetate (Alfadolone acetate) is a steroid anaesthetic, with antinociception .

Alphadolone acetate Alfadolone acetate; GR 2/1574	Others	Neurological Disease
Alphadolone acetate (Alfadolone acetate) is a steroid anaesthetic, with antinociception .

HY-W017277

(+)-Menthol D-Menthol	Others	Neurological Disease
(+)-Menthol (D-Menthol) is one of the optical isomers of Menthol. (+)-Menthol can reduce the electrically evoked contractions of rat phrenic hemidiaphragm in vitro. Local anaesthetic activity. (+)-Menthol can also inhibit the growth of Microcystis aeruginosa cells .

HY-117979

Alphadolone

Alfadolone
Others Cancer

Alphadolone is an intravenous anaesthetics. Alphadolone causes general anaesthesia .
HY-B1656

Fomocaine

P 652
Others Cardiovascular Disease Neurological Disease

Fomocaine (P 652) is an orally active local anaesthetic. Fomocaine shows antiarrhythmic activity .

Alphadolone Alfadolone	Others	Cancer
Alphadolone is an intravenous anaesthetics. Alphadolone causes general anaesthesia .

Fomocaine P 652	Others	Cardiovascular Disease Neurological Disease
Fomocaine (P 652) is an orally active local anaesthetic. Fomocaine shows antiarrhythmic activity .

HY-W011777S

Tricaine-d5 methanesulfonate MS-222-d₅	Isotope-Labeled Compounds	Neurological Disease
Tricaine-d₅ (methanesulfonate) is the deuterium labeled Tricaine-d5 methanesulfonate. Tricaine methanesulfonate (MS-222) is a commonly used anaesthetic agent for immobilization of aquatic species. Tricaine methanesulfonate, the most widely used anaesthetic in fish, has been shown to induce embryotoxic effects in zebrafish[1][2].

HY-148157

Amylocaine	Others	Others
Amylocaine is a local anaesthetic of the ester type. Amylocaine can cause reversible insensitization near the area where it is administered. Amylocaine is used mostly in spinal anesthesia .

HY-P1952

µ-Conotoxin-CnIIIC	Sodium Channel	Inflammation/Immunology
μ-Conotoxin-CnIIIC is a 22-residue conopeptide that can be isolated from Conus consors. μ-Conotoxin-CnIIIC is a potent and persistent blocker of Na_V1.4 channel. μ-Conotoxin-CnIIIC has analgesic, anaesthetic and myorelaxant properties .

HY-B0653A

Levobupivacaine hydrochloride 2 Publications Verification (S)-(-)-Bupivacaine monohydrochloride	Sodium Channel Ferroptosis	Neurological Disease Cancer
Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a long-acting amide local anaesthetic. Levobupivacaine hydrochloride exerts anaesthetic and analgesic effects through reversible blockade of neuronal sodium channel. Levobupivacaine hydrochloride can inhibit impulse transmission and conduction in cardiovascular and other tissues, possessing certain cardiac and CNS toxicity. Levobupivacaine hydrochloride is metabolized by hepatic cytochrome P450 (CYP450) enzymes in vivo. Levobupivacaine hydrochloride can also induce ferroptosis by miR-489-3p/SLC7A11 signaling in gastric cancer .

HY-B0653

Levobupivacaine (S)-(-)-Bupivacaine	Sodium Channel Ferroptosis	Neurological Disease Cancer
Levobupivacaine ((S)-(-)-Bupivacaine) is a long-acting amide local anaesthetic. Levobupivacaine exerts anaesthetic and analgesic effects through reversible blockade of neuronal sodium channel. Levobupivacaine can inhibit impulse transmission and conduction in cardiovascular and other tissues, possessing certain cardiac and CNS toxicity. Levobupivacaine is metabolized by hepatic cytochrome P450 (CYP450) enzymes in vivo. Levobupivacaine can also induce ferroptosis by miR-489-3p/SLC7A11 signaling in gastric cancer .

HY-B0563C

Ropivacaine mesylate 4 Publications Verification	Sodium Channel Potassium Channel	Cardiovascular Disease Neurological Disease
Ropivacaine mesylate is a long-acting amide local anaesthetic agent for a spinal block and effectively blocks neuropathic pain. Ropivacaine blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibressup>[1] . Ropivacaine is also an inhibitor of K_2P (two-pore domain potassium channel) TREK-1 with an IC₅₀ of 402.7 μM in COS-7 cell's membrane .

HY-B1226

Diperodon hydrochloride

Others Neurological Disease

Diperodon is a local anaesthetics, by the action of hydrolazes in blood serum is decomposed.
HY-105584

Tolycaine

Others Neurological Disease

Tolycaine is a local anaesthetic. Tolycaine also induces a convulsive response in experimental animals .

Diperodon hydrochloride	Others	Neurological Disease
Diperodon is a local anaesthetics, by the action of hydrolazes in blood serum is decomposed.

Tolycaine	Others	Neurological Disease
Tolycaine is a local anaesthetic. Tolycaine also induces a convulsive response in experimental animals .

HY-107040

Etoxadrol NSC 288020; CL-1848C	Others	Others
Etoxadrol (CL-1848C) is a potent N-methyl-D-aspartic acid (NMDA) antagonist with high affinity. Etoxadrol can be used for *anaesthetic* research .

HY-116152S

Cipepofol-d6 Ciprofol-d₆; HSK3486-d₆	Isotope-Labeled Compounds GABA Receptor	Neurological Disease
Cipepofol-d₆ (Ciprofol-d₆; HSK3486-d₆) is deuterium labeled Cipepofol (HY-116152). Cipepofol (HSK3486), a psychomotor stabilizing agent, is a gamma-aminobutyric acid (GABA) receptor potentiator.

HY-116152S2

Cipepofol-d6-2 Ciprofol-d₆-2; HSK3486-d₆-2	Isotope-Labeled Compounds GABA Receptor	Neurological Disease
Cipepofol-d₆-2 (Ciprofol-d₆-2; HSK3486-d₆-2) is deuterium labeled Cipepofol (HY-116152). Cipepofol (HSK3486), a psychomotor stabilizing agent, is a gamma-aminobutyric acid (GABA) receptor potentiator.

HY-B0516

Articaine hydrochloride Hoe-045	Sodium Channel NF-κB NOD-like Receptor (NLR)	Neurological Disease
Articaine hydrochloride (Hoe-045) is an amide anaesthetic containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine hydrochloride ameliorates LPS-induced acute kidney injury via inhibition of NF-ĸB activation and the NLRP3 inflammasome pathway .

HY-B0516A

Articaine Hoe-045 free base	NF-κB NOD-like Receptor (NLR) Sodium Channel	Inflammation/Immunology
Articaine (Hoe-045 free base) is an amide anaesthetic containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine ameliorates LPS-induced acute kidney injury via inhibition of NF-ĸB activation and the NLRP3 inflammasome pathway .

HY-B0516R

Articaine hydrochloride (Standard) Hoe-045 (Standard)	Sodium Channel NF-κB NOD-like Receptor (NLR)	Neurological Disease
Articaine (hydrochloride) (Standard) is the analytical standard of Articaine (hydrochloride). This product is intended for research and analytical applications. Articaine hydrochloride (Hoe-045) is an amide anaesthetic containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine hydrochloride ameliorates LPS-induced acute kidney injury via inhibition of NF-ĸB activation and the NLRP3 inflammasome pathway .

HY-B0563B

Ropivacaine hydrochloride 4 Publications Verification	Sodium Channel Potassium Channel	Cardiovascular Disease Neurological Disease Cancer
Ropivacaine hydrochloride is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese . Ropivacaine is also an inhibitor of K_2P (two-pore domain potassium channel) TREK-1 with an IC₅₀ of 402.7 μM in COS-7 cell's membrane . Ropivacaine is widely used for neuropathic pain management in vivo .

HY-B0563

Ropivacaine 4 Publications Verification	Sodium Channel Potassium Channel	Cardiovascular Disease Neurological Disease
Ropivacain is a potent sodium channel blocker. Ropivacain blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese . Ropivacaine is also an inhibitor of K_2P (two-pore domain potassium channel) TREK-1 with an IC₅₀ of 402.7 μM in COS-7 cell's membrane . Ropivacaine is used for the research of neuropathic pain management .

HY-B0563BS

Ropivacaine-d7 hydrochloride	Isotope-Labeled Compounds	Neurological Disease
Ropivacaine-d₇ hydrochloride is a deuterium labeled Ropivacaine (hydrochloride) (HY-B0563B) . Ropivacaine hydrochloride is a potent?sodium channel?blocker and blocks impulse conduction via reversible inhibition of?sodium ion influx?in nerve fibrese . Ropivacaine is also an inhibitor of K_2P (two-pore domain potassium channel) TREK-1 with an IC₅₀ of 402.7 μM in COS-7 cell's membrane . Ropivacaine is widely used for neuropathic pain?management in vivo .

µ-Conotoxin-CnIIIC	Sodium Channel	Inflammation/Immunology
μ-Conotoxin-CnIIIC is a 22-residue conopeptide that can be isolated from Conus consors. μ-Conotoxin-CnIIIC is a potent and persistent blocker of Na_V1.4 channel. μ-Conotoxin-CnIIIC has analgesic, anaesthetic and myorelaxant properties .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W017277

(+)-Menthol D-Menthol	Natural Products Labiatae Source classification Erythrina poeppigiana Plants	Others
(+)-Menthol (D-Menthol) is one of the optical isomers of Menthol. (+)-Menthol can reduce the electrically evoked contractions of rat phrenic hemidiaphragm in vitro. Local anaesthetic activity. (+)-Menthol can also inhibit the growth of Microcystis aeruginosa cells .

Cat. No.	Product Name	Chemical Structure

HY-B0563BS

Ropivacaine-d7 hydrochloride
Ropivacaine-d₇ hydrochloride is a deuterium labeled Ropivacaine (hydrochloride) (HY-B0563B) . Ropivacaine hydrochloride is a potent?sodium channel?blocker and blocks impulse conduction via reversible inhibition of?sodium ion influx?in nerve fibrese . Ropivacaine is also an inhibitor of K_2P (two-pore domain potassium channel) TREK-1 with an IC₅₀ of 402.7 μM in COS-7 cell's membrane . Ropivacaine is widely used for neuropathic pain?management in vivo .

Ropivacaine-d7 hydrochloride

Ropivacaine-d₇ hydrochloride is a deuterium labeled Ropivacaine (hydrochloride) (HY-B0563B) . Ropivacaine hydrochloride is a potent?sodium channel?blocker and blocks impulse conduction via reversible inhibition of?sodium ion influx?in nerve fibrese . Ropivacaine is also an inhibitor of K_2P (two-pore domain potassium channel) TREK-1 with an IC₅₀ of 402.7 μM in COS-7 cell's membrane . Ropivacaine is widely used for neuropathic pain?management in vivo .