Search Result
Results for "
analog
" in MCE Product Catalog:
1958
Inhibitors & Agonists
27
Biochemical Assay Reagents
34
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
-
- HY-136203
-
-
- HY-136204
-
-
- HY-10531
-
|
ARRY-380 analog
|
EGFR
|
Cancer
|
|
ARRY-380 analog, an inhibitor of EGFR (ErbB1), is extracted from patent WO2015153959A2, compound 249. ARRY-380 is a potent, selective, ATP-competitive, orally active inhibitor of HER2.
|
-
- HY-N10492
-
|
Spongionellol A analog 1
|
P-glycoprotein
|
Cancer
|
|
Spongionellol A analog 1, an analog of Spongionellol A (HY-10491), is a MDR1 (p-glycoprotein) inhibitor. Spongionellol A analog 1 has high cytotoxic activity and selectivity in prostate cancer cells by inducing caspase‑dependent apoptosis. Spongionellol A analog 1 can be used in the research of cancers, such as prostate cancer.
|
-
- HY-128979
-
|
Deruxtecan analog 2
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Deruxtecan analog 2 (example 9 P3) is a Deruxtecan (HY-13631E) analog. Deruxtecan analog 2 is a agent-linker conjugate composed of Camptothecin (HY-16560) and a linker. Camptothecin (CPT) is a Topo I inhibitor with antineoplastic activity against colorectal, breast, lung and ovarian cancers. Deruxtecan analog 2 can be used for the preparation anti-FGFR2 ADC.
|
-
- HY-115666
-
-
- HY-148091
-
-
- HY-129355
-
-
- HY-128606
-
-
- HY-135237
-
-
- HY-P1577
-
-
- HY-15966A
-
-
- HY-15966
-
-
- HY-135593
-
|
LY88074 analog 1
|
Others
|
Endocrinology
|
|
LY88074 analog 1 is a benzothiophene compound with nitrogen-containing non-basic side chains, Compound 26, extracted from patent EP0747380A1. LY88074 analog 1 is an agent for alleviating the symptoms of post-menopausal symptoms, such as osteoporosis, cardiovascular related pathological conditions, and estrogen-dependent cancer. LY88074 analog 1 can be used alone or in combination with estrogen or progestin.
|
-
- HY-19430
-
-
- HY-18951
-
-
- HY-146146
-
|
Kolavenic acid analog
KAA
|
Kinesin
|
Cancer
|
|
Kolavenic acid analog (KAA) is an anticancer agent. Kolavenic acid analog shows strong activity against HSET-overproducing yeast cells. Kolavenic acid analog inhibits centrosome clustering in human cancer cells containing high HSET levels and supernumerary centrosomes.
|
-
- HY-134654
-
|
MRTX849 analog 24
|
Others
|
Cancer
|
|
MRTX849 analog 24 is an alkyne-containing click probe analogue of KRAS G12C inhibitor MRTX849, which is used to research MRTX849 function.
|
-
- HY-133875
-
-
- HY-10991
-
|
MGCD-265 analog
|
c-Met/HGFR
VEGFR
Apoptosis
|
Cancer
|
|
MGCD-265 analog is a potent and oral active inhibitor of c-Met and VEGFR2 tyrosine kinases, with IC50s of 29 nM and 10 nM, respectively. MGCD-265 analog has significant antitumor activity.
|
-
- HY-100112
-
|
WEHI-345 analog
|
RIP kinase
|
Others
|
|
WEHI-345 analog is the analog of WEHI-345. WEHI-345 is a potent and selective RIPK2 kinase inhibitor with an IC50 of 0.13 μM, which delays RIPK2 ubiquitylation and NF-κB activation on oligomerization domain (NOD) stimulation.
|
-
- HY-103652
-
-
- HY-77651
-
-
- HY-141453
-
|
Desmethyl-WEHI-345 analog
|
RIP kinase
|
Cancer
|
|
Desmethyl-WEHI-345 analog is a protein kinase inhibitor extracted from patent WO2012003544A1, example 12. Desmethyl-WEHI-345 analog can be used for the research of colon cancer.
|
-
- HY-112205A
-
|
RR-11a analog
|
Parasite
Legumain
|
Infection
|
|
RR-11a analog is a potent and irreversible inhibitor of Schistosoma mansoni legumain, with an IC50 of 31 nM. RR-11a analog is an aza-Asn derivative and aza-peptide Michael acceptor.
|
-
- HY-77652
-
-
- HY-117771A
-
-
- HY-10862
-
|
FAAH inhibitor 1
Benzothiazole analog 3
|
FAAH
Autophagy
|
Cancer
|
|
FAAH inhibitor 1 (Benzothiazole analog 3) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 18±8 nM.
|
-
- HY-12395
-
|
Ecteinascidin-Analog-1
|
Others
|
Cancer
|
|
Ecteinascidin-Analog-1 is a useful intermediate for chemical sythesis of Ecteinascidin analogues; Ecteinascidins is a family of tetrahydroisoquinoline alkaloids with wide range of antitumor and antimicrobial activities.
|
-
- HY-13961
-
|
GLPG0634 analog
|
JAK
|
Cancer
|
|
GLPG0634 analog (Compoun 176) is a broad spectrum JAK inhibitor with IC50 values of <100 nM against JAK1, JAK2 and JAK3.
|
-
- HY-B1714
-
|
NSC 601980 (analog)
|
Others
|
Cancer
|
|
NSC 601980 analog is the analog of the NSC601980, NSC601980 shows antitumor activity in the yeast screening experiment, which can inhibit cell proliferation in the COLO 205 and HT29 with Log GI 50 of -6.6 and -6.9 respectively.
|
-
- HY-P3943
-
-
- HY-104022
-
-
- HY-101941
-
-
- HY-12039
-
|
Lyn-IN-1
Bafetinib analog
|
Bcr-Abl
|
Cancer
|
|
Lyn-IN-1 (Bafetinib analog) is a potent and selective dual Bcr-Abl/Lyn inhibitor, extracted from patent WO2014169128A1.
|
-
- HY-13464
-
-
- HY-15625
-
|
Hoechst 33258 analog 3
|
DNA Stain
|
Others
|
|
Hoechst 33258 analog 3 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution. Storage: Keep away from light.
|
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- HY-15630A
-
|
Hoechst 33342 analog 2 trihydrochloride
|
Fluorescent Dye
|
Others
|
|
Hoechst 33342 analog 2 trihydrochloride is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution. Storage: Keep away from light.
|
-
- HY-15630
-
|
Hoechst 33342 analog 2
|
Fluorescent Dye
|
Cancer
|
|
Hoechst 33342 analog 2 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution. Storage: Keep away from light.
|
-
- HY-15631
-
|
Hoechst 33258 analog 6
|
Fluorescent Dye
|
Others
|
|
Hoechst 33258 analog 6 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution. Storage: Keep away from light.
|
-
- HY-15628
-
|
Hoechst 33258 analog 5
|
DNA Stain
|
Others
|
|
Hoechst 33258 analog 5 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution. Storage: Keep away from light.
|
-
- HY-15624
-
|
Hoechst 33258 analog 2
|
DNA Stain
|
Cancer
|
|
Hoechst 33258 analog 2 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution. Storage: Keep away from light.
|
-
- HY-18676B
-
-
- HY-135596
-
-
- HY-U00423
-
-
- HY-78869
-
|
Mutated EGFR-IN-1
Osimertinib analog
|
EGFR
|
Cancer
|
|
Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant and T790M resistance mutant.
|
-
- HY-124594
-
-
- HY-U00347
-
-
- HY-101766
-
-
- HY-15627
-
|
Hoechst 33342 analog
|
Fluorescent Dye
|
Others
|
|
Hoechst 33342 analog is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution. Storage: Keep away from light.
|
-
- HY-15627A
-
|
Hoechst 33342 analog trihydrochloride
|
Fluorescent Dye
DNA Stain
|
Others
|
|
Hoechst 33342 analog trihydrochloride is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution. Storage: Keep away from light.
|
-
- HY-15623
-
|
Hoechst 33258 analog
|
DNA Stain
|
Others
|
|
Hoechst 33258 analog is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution. Storage: Keep away from light.
|
-
- HY-13942
-
|
1-NM-PP1
PP1 analog II
|
Src
|
Cancer
|
|
1-NM-PP1, a cell-permeable PP1 analog, is a potent Src family kinases inhibitor with IC50s of 4.3 nM and 3.2 nM for v-Src-as1 and c-Fyn-as1, respectively.
|
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- HY-102024
-
-
- HY-134321
-
-
- HY-112535
-
-
- HY-21586B
-
-
- HY-110407
-
-
- HY-106233
-
|
Tiviciclovir
AM188
|
HBV
|
Infection
|
|
Tiviciclovir (AM188) is an antiviral guanosine analog and a hepatitis B virus inhibitor.
|
-
- HY-139085A
-
-
- HY-B1798A
-
|
Tocainide hydrochloride
|
Sodium Channel
|
Inflammation/Immunology
|
|
Tocainide hydrochloride is a sodium channel blocker, it blocks the sodium channels in the pain-producing foci in the nerve membranes. Tocainide hydrochloride is a primary amine analog of lidocaine, can be used for the treatment of tinnitus.
|
-
- HY-108719
-
-
- HY-139085B
-
-
- HY-147178
-
|
C-6 NBD-dihydro-Ceramide
|
Others
|
Others
|
|
C-6 NBD-dihydro-Ceramide is a membrane-permeable ceramides. C-6 NBD-dihydro-Ceramide is a biologically active fluorescent analog of short chain.
|
-
- HY-147782
-
|
Anticancer agent 67
|
Apoptosis
|
Cancer
|
|
Anticancer agent 67 (Compound 13g) is an anti-cancer agent. Anticancer agent 67 induces apoptosis and increases sub-G1 cell population in MCF-7 cells. Anticancer agent 67 is a ciprofloxacin analog.
|
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- HY-147781
-
|
Anticancer agent 66
|
Apoptosis
|
Cancer
|
|
Anticancer agent 66 (Compound 13e) is an anti-cancer agent. Anticancer agent 66 induces apoptosis and increases sub-G1 cell population in MCF-7 cells. Anticancer agent 66 is a ciprofloxacin analog.
|
-
- HY-13670
-
|
Lurtotecan
GI147211; OSI-211
|
Topoisomerase
|
Cancer
|
|
Lurtotecan (GI147211; OSI-211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan has anticancer effects.
|
-
- HY-107621
-
|
U0124
|
MEK
|
Cancer
|
|
U0124, an inactive U0126 analog, has no effect on c-Fos and c-Jun protein or mRNA levels. U0126 is a MEK inhibitor. U0124 does not inhibit MEK at concentrations up to 100 μM.
|
-
- HY-N0449
-
-
- HY-N8488
-
|
Anhydro-6-epiophiobolin A
|
Others
|
Others
|
|
Anhydro-6-epiophiobolin A, an analog of Ophiobolin A, is a potent inhibitor of photosynthesis (I50s of 6.1 and 1 mM for photosynthesis in Chlorella and Spinach, respectively).
|
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- HY-106425
-
|
Omzotirome
TRC-150094
|
Others
|
Metabolic Disease
|
|
Omzotirome (TRC150094), a functional analog of iodothyronines, can be used for the research of hyperlipidaemia (WO2008149379).
|
-
- HY-137267
-
-
- HY-115890
-
|
Thiocysteine
|
Reactive Oxygen Species
|
Others
|
|
Thiocystine is the trisulfide analog of cysteine, it can modify cysteine in proteins. Thiocystine is an activator for aminolevulinate synthetase. Thiocystine can be used for cysteine metabolism research.
|
-
- HY-B0018
-
|
Docetaxal
10-Acetyl docetaxel; PNU-101383
|
Others
|
Cancer
|
|
Docetaxal (10-Acetyl docetaxel) is an analog of Docetaxel (HY-B0011), with anticancer activity. Docetaxel is a microtubule disassembly inhibitor, with antimitotic activity.
|
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- HY-134320
-
-
- HY-115749
-
|
D-Luciferin 6′-methyl ether
6′-Methoxyluciferin
|
Others
|
Others
|
|
D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC50 of 0.1 µM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site.
|
-
- HY-P3922
-
-
- HY-19688B
-
|
Sitamaquine tosylate
WR 6026 tosylate
|
Parasite
|
Infection
|
|
Sitamaquine (WR 6026) tosylate, an orally active 8-aminoquinoline analog, is an antileishmanial agent. Sitamaquine is a lipophilic weak base that rapidly accumulates in acidic compartments of Leishmania spp., mainly in acidocalcisomes.
|
-
- HY-P3925
-
-
- HY-W127851
-
|
CLA
Cypridina luciferin analog
|
Biochemical Assay Reagents
|
Others
|
|
CLA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-107917
-
-
- HY-P3580
-
-
- HY-112367
-
|
SB 202474
|
Others
|
Cancer
|
|
SB 202474, a negative analog of SB203580. SB 202474, which has no ability to inhibit p38 MAPK activity and is widely used as a negative control compound in p38 MAPK studies, also suppressed melanin synthesis induction.
|
-
- HY-118384
-
|
Sangivamycin
NSC 65346; BA-90912
|
PKC
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Sangivamycin (NSC 65346), a nucleoside analog, is a potent inhibitor of protein kinase C (PKC) with an Ki of 10 μM. Sangivamycin has potent antiproliferative activity against a variety of human cancers.
|
-
- HY-111616
-
|
GSK1820795A
|
PPAR
Angiotensin Receptor
|
Others
|
|
GSK1820795A, as a telmisartan analog, is a selective hGPR132a antagonist. GSK1820795A blocks activation of yeast cells expressing hGPR132a by N-acylamides. GSK1820795A is also a angiotensin II antagonists and partial PPARγ agonists (compound 38).
|
-
- HY-145246
-
-
- HY-P3927
-
-
- HY-77554
-
|
Cephalomannine
|
Microtubule/Tubulin
|
Cancer
|
|
Cephalomannine is a Paclitaxel (HY-B0015) alkaloidal analog and isolated from most Cephalotaxus species. Cephalomannine is an orally active anti-tumor agent and can be used as a chemotherapy agent for cancer research.
|
-
- HY-101677
-
|
cPrPMEDAP
|
Drug Metabolite
|
Infection
|
|
cPrPMEDAP is an intermediate metabolite of GS-9219. cpr-PMEDAP functions as a proagent of the guanine nucleotide analog PMEG and has antiproliferative activity. cPrPMEDAP is negatively charged at physiologic pH and has poor permeability into the skin.
|
-
- HY-W091784
-
-
- HY-118421
-
|
Nullscript
|
Parasite
HDAC
|
Infection
|
|
Nullscript is a negative control for Scriptaid. Nullscript is a known inactive analog of Scriptaid. Scriptaid is a representative HDAC inhibitor. Nullscript inhibits Cryptosporidium (C. parvum) growth with the IC50 value of 2.1 μM.
|
-
- HY-121295
-
|
Roseoflavin
|
Bacterial
|
Infection
|
|
Roseoflavin, a natural pigment originally isolated from Streptomyces davawensis, is an antimetabolite analog of Riboflavin and flavin mononucleotide that has antimicrobial properties.
|
-
- HY-145247
-
-
- HY-W012642A
-
|
2-Aminopurine dihydrochloride
|
DNA Stain
|
Others
|
|
2-Aminopurine dihydrochloride is a fluorescent analog of guanosine. 2-Aminopurine dihydrochloride can be used as a fluorescence probe for nucleic acid structure and dynamics. Incorporating 2-Aminopurine dihydrochloride into DNA quenches its fluorescence. Storage: protect from light.
|
-
- HY-106689
-
-
- HY-A0057
-
|
Gabapentin
|
Calcium Channel
|
Neurological Disease
Cancer
|
|
Gabapentin is a potent, orally active P/Q type Ca 2+ channel blocker. Gabapentin inhibits neuronal Ca 2+ influx and reduction of neurotransmitter release. Gabapentin is a GABA analog that can be used to relieve neuropathic pain.
|
-
- HY-A0057A
-
|
Gabapentin hydrochloride
|
Calcium Channel
|
Neurological Disease
Cancer
|
|
Gabapentin hydrochloride is a potent, orally active P/Q type Ca 2+ channel blocker. Gabapentin hydrochloride inhibits neuronal Ca 2+ influx and reduction of neurotransmitter release. Gabapentin hydrochloride is a GABA analog that can be used to relieve neuropathic pain.
|
-
- HY-16200
-
-
- HY-145248
-
-
- HY-147099
-
|
dTAG-47-NEG
|
PROTACs
|
Cancer
|
|
dTAG-47-NEG is an analog of dTAG-47 that cannot bind and recruit cereblon (CRBN). dTAG-47-NEG can be used as a heterobifunctional negative control of dTAG-47.
|
-
- HY-D1578
-
|
C12FDGlcU
|
Fluorescent Dye
|
Others
|
|
C12FDGlcU is a lipophilic analog of fluorescein di-β-D-glucuronic acid. C12FDGlcU can be useful for the detection of β-glucuronidase (GUS) gene expression. C12FDGlcU can enter the cells and then be cleaved by β-glucuronidase, generating the yellow-colored, green-fluorescent fluorescein (Abs/Em of the reaction product: 495/518 nm).
|
-
- HY-100571
-
-
- HY-P2217
-
|
Aclerastide
DSC-127; NorLeu3-A(1-7)
|
Angiotensin Receptor
|
Inflammation/Immunology
|
|
Aclerastide (DSC-127) is an angiotensin receptor agonist. Aclerastide also is a peptide analog of angiotensin II. Aclerastide can be used for the research of tissue regeneration in diabetic ulcers.
|
-
- HY-100838A
-
|
L-CCG-I
|
mGluR
|
Metabolic Disease
|
|
L-CCG-I is an extended isomer of conformationally restricted glutamate analog. L-CCG-I also is a potent agonist for mGluR2 with an EC50 value of 0.3 nM. L-CCG-I can be used for the research of mGluR family.
|
-
- HY-135878
-
-
- HY-13859
-
|
Clevudine
L-FMAU
|
HBV
DNA/RNA Synthesis
Orthopoxvirus
|
Infection
|
|
Clevudine (L-FMAU), a nucleoside analog of the unnatural L-configuration, has potent anti-HBV activity with long half-life, low toxicity. Clevudine is a non-competitive inhibitor that is not incorporated into the viral DNA but rather binds to the polymerase. Clevudine is active against cowpox virus respiratory infection in mice.
|
-
- HY-108060A
-
-
- HY-140345A
-
|
L-Homopropargylglycine hydrochloride
|
PROTAC Linkers
|
Cancer
|
|
L-Homopropargylglycine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine hydrochloride is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor.
|
-
- HY-108060
-
-
- HY-140345
-
|
L-Homopropargylglycine
|
PROTAC Linkers
|
Cancer
|
|
L-Homopropargylglycine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor.
|
-
- HY-152210
-
|
ASPER-29
|
Cathepsin
|
Cancer
|
|
ASPER-29 is Asperphenamate HY-129578 analog. ASPER-29 also is a dual cathepsin L and S inhibitor with IC50 value of 6.03 μM and 5.02 μM, respectively. ASPER-29 can be used for the research of the migration and invasion of cancer.
|
-
- HY-W011793
-
|
4-Thiouridine
|
Others
|
Others
|
|
4-Thiouridine is a ribonucleoside analog, it is widely used in RNA analysis and (m)RNA labeling. 4-Thiouridine inhibits rRNA synthesis and causes a nucleolar stress response.
|
-
- HY-145969
-
|
β-S-ARCA
|
Others
|
Others
|
|
β-S-ARCA is a mRNA 7-methylguanosine (m 7G) cap analog carrying a phosphorothioate (PS) moiety. mRNAs incorporating β-S-ARCA have elongated cellular half-lives and showed augmented protein expression. β-S-ARCA D1 has been applied in researching experimental mRNA-based anticancer vaccines.
|
-
- HY-W012009
-
|
2'-Deoxy-2'-fluorocytidine
|
Influenza Virus
|
Infection
|
|
2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency of both compounds antiviral effects on CCHFV replication.
|
-
- HY-124758
-
|
SH-BC-893
|
Mitochondrial Metabolism
|
Cancer
Metabolic Disease
|
|
SH-BC-893 is an orally active anti-neoplastic sphingolipid analog. SH-BC-893 also protects from ceramide-induced mitochondrial dysfunction and corrects diet-induced obesity. SH-BC-893 can be used for the research of cancer and obesity.
|
-
- HY-43722
-
|
Lenalidomide-Br
|
Ligands for E3 Ligase
|
Cancer
|
|
Lenalidomide-Br (Compound 41) is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein. Lenalidomide-Br can be connected to the ligand for protein by a linker to form PROTACs, such as the PROTAC STAT3 degrader SD-36 (HY-129602).
|
-
- HY-130838
-
|
JH-LPH-33
|
Bacterial
|
Infection
|
|
JH-LPH-33, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-33 displays outstanding antibiotic activity with a MIC value of 0.66 μg/mL.
|
-
- HY-130837
-
|
JH-LPH-28
|
Bacterial
|
Infection
|
|
JH-LPH-28, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-28 displays outstanding antibiotic activity with a MIC value of 0.83 μg/mL.
|
-
- HY-A0245
-
|
Dihydrotachysterol
|
VD/VDR
|
Metabolic Disease
|
|
Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body) .
|
-
- HY-109014
-
|
Tenofovir exalidex
CMX-157
|
HIV
HBV
Nucleoside Antimetabolite/Analog
|
Infection
|
|
Tenofovir exalidex (CMX157) is a lipid conjugate of the acyclic nucleotide analog Tenofovir with activity against both wild-type and antiretroviral drug-resistant HIV strains, including multidrug nucleoside/nucleotide analog-resistant viruses. Tenofovir exalidex is active against all major subtypes of HIV-1 and HIV-2 in fresh human PBMCs and against all HIV-1 strains evaluated in monocyte-derived macrophages, with EC50s ranging between 0.2 and 7.2 nM. CMX157 is orally available and has no apparent toxicity. Tenofovir exalidex also shows antiviral activity against HBV.
|
-
- HY-13622A
-
|
Elomotecan
BN 80927 free base
|
Topoisomerase
|
Cancer
|
|
Elomotecan (BN 80927 free base) is a potent inhibitor of topoisomerases I and II. Elomotecan is a camptothecin analog belonging to the homocamptothecin family (hCPT). Elomotecan reduces the proliferation of different tumor cells with higher potency than other anticancer agents of reference targeting topoisomerases I and II.
|
-
- HY-103237
-
|
L-Adenosine
|
Adenosine Deaminase
|
Neurological Disease
|
|
L-Adenosine is a metabolically stable enantiomeric analog and also is a potential probe. L-Adenosine has weakly inhibitory adenosine deaminase (ADA) activity with an Ki value of 385 μM. L-Adenosine can be used for the research of adenosine uptake and accumulation.
|
-
- HY-130812
-
-
- HY-18649
-
|
Galidesivir hydrochloride
BCX4430 hydrochloride; Immucillin-A hydrochloride
|
DNA/RNA Synthesis
SARS-CoV
Filovirus
|
Infection
|
|
Galidesivir (BCX4430) hydrochloride, an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir hydrochloride is active in vitro against many RNA viral pathogens, including the filoviruses and emerging infectious agents such as MERS-CoV, SARS-CoV, and SARS-CoV-2. Galidesivir hydrochloride inhibits some negative-sense RNA viruses with EC50s ranging from ~3 to ~68 μM.
|
-
- HY-18649A
-
|
Galidesivir
BCX4430; Immucillin-A
|
DNA/RNA Synthesis
SARS-CoV
Filovirus
|
Infection
|
|
Galidesivir (BCX4430), an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir is active in vitro against many RNA viral pathogens, including the filoviruses and emerging infectious agents such as MERS-CoV, SARS-CoV, and SARS-CoV-2. Galidesivir inhibits some negative-sense RNA viruses with EC50s ranging from ~3 to ~68 μM.
|
-
- HY-13622
-
|
Elomotecan hydrochloride
BN 80927
|
Topoisomerase
|
Cancer
|
|
Elomotecan hydrochloride (BN 80927) is a potent inhibitor of topoisomerases I and II. Elomotecan hydrochloride (BN 80927) is a camptothecin analog belonging to the homocamptothecin family (hCPT). Elomotecan hydrochloride (BN 80927) reduces the proliferation of different tumor cells with higher potency than other anticancer agents of reference targeting topoisomerases I and II.
|
-
- HY-131233
-
|
Anti-virus agent 1
Remdesivir isopropyl ester analog
|
Antibiotic
|
Infection
|
|
Anti-virus agent 1 (compound 4i), a phosphoramidate proagent of GS-5734 (HY-104077; Remdesivir), has potent antiviral activity. Anti-virus agent 1 is used for the research of coronavirus and Ebola virus (EBOV).
|
-
- HY-146098
-
|
Antibacterial agent 105
|
Bacterial
Antibiotic
|
Infection
|
|
Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones show antibacterial activity against M. tuberculosis with antibacterial activity (MIC90=2.64 μM)。Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC90s of 11.18, 11.18，0.70，1.40，44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum,BCG, E. aerogenes and S. aureus, respectively.
|
-
- HY-116705
-
|
2-Deoxy-2-fluoro-L-fucose
|
Others
|
Cancer
|
|
2-Deoxy-2-fluoro-L-fucose, an L-fucose analog, is a fucosylation inhibitor. 2-Deoxy-2-fluoro-L-fucose inhibits de novo synthesis of GDP-fucose in mammalian cells. Fucosylation is a relatively well-defined biomarker for progression in many human cancers; for example, pancreatic and hepatocellular carcinoma.
|
-
- HY-D1603
-
|
BODIPY FL-EDA
|
Fluorescent Dye
|
Others
|
|
BODIPY FL-EDA is a fluorescent dye. BODIPY FL-EDA is an aliphatic-amine analog, and it can be coupled with aldehydes and ketones. BODIPY FL-EDA can be used for the detection of modified and normal deoxynucleotides and to determine DNA damage and genomic DNA methylation.
|
-
- HY-P1208
-
|
PG-931
|
Melanocortin Receptor
|
Inflammation/Immunology
|
|
PG-931, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor (IC50=0.58 nM) agonist and is more selective than for the hMC3R (IC50=55 nM) or the hMC5R (IC50=2.4 nM). PG-931 can reverse haemorrhagic shock and prevent multiple organ damage in vivo.
|
-
- HY-16785
-
|
Veledimex
INXN-1001; RG-115932
|
Interleukin Related
|
Cancer
Inflammation/Immunology
|
|
Veledimex (INXN-1001), a synthetic analog of the insect molting hormone ecdysone, is an orally active activator ligand for a proprietary gene therapy promoter system. Veledimex can be used to activate certain genes using the ecdysone receptor (EcR)-based inducible gene regulation system, the RheoSwitch Therapeutic System (RTS). Veledimex can cross blood-brain barrier (BBB) in both orthotopic GL-261 mice and cynomolgus monkeys.
|
-
- HY-P1208A
-
|
PG-931 TFA
|
Melanocortin Receptor
|
Inflammation/Immunology
|
|
PG-931 TFA, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor (IC50=0.58 nM) agonist and is more selective than for the hMC3R (IC50=55 nM) or the hMC5R(IC50=2.4 nM). PG-931 TFA can reverse haemorrhagic shock and prevent multiple organ damage in vivo.
|
-
- HY-106916
-
|
Unoprostone
|
Potassium Channel
|
Neurological Disease
|
|
Unoprostone, a prostaglandin F2α analogs (PGAs), activates BK channels to reduce oxidative stress- and light-induced retinal cell death, and phagocytotic dysfunction. Unoprostone reduces intraocular pressure and is used topically for glaucoma or ocular hypertension.
|
-
- HY-108391
-
|
C8-Ceramide
N-Octanoyl-D-erythro-sphingosine
|
Apoptosis
PKC
Autophagy
|
Cancer
Inflammation/Immunology
|
|
C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) is a cell-permeable analog of naturally occurring ceramides. C8-Ceramide has anti-proliferation properties and acts as a potent chemotherapeutic agent. C8-Ceramide stimulates dendritic cells to promote T cell responses upon virus infections. C8-Ceramide induces slight activation of protein kinase (PKC) in vitro.
|
-
- HY-101544
-
|
ARQ 069
|
FGFR
|
Cancer
|
|
ARQ 069, an analog of ARQ 523, inhibits FGFR in an enantiospecific manner. ARQ 069 targets the unphosphorylated, inactive forms of FGFR1/FGFR2 kinases (IC50s of 0.84 μM and 1.23 μM, respectively). ARQ 069 inhibits FGFR1/FGFR2 autophosphorylation (IC50s of 2.8 and 1.9 μM, respectively) through a mechanism in a non-ATP competitive dependent manner.
|
-
- HY-W002585
-
|
O6-Benzylguanine
|
DNA/RNA Synthesis
Apoptosis
|
Cancer
|
|
O6-Benzylguanine, a guanine analog, is the DNA repair enzyme O6-alkylguanine-DNA alkyltransferase (MGMT/AGT) inhibitor. O6-Benzylguanine acts as an AGT substrate, which transfers its benzyl group to the AGT cysteine residue, thereby irreversibly inactivating AGT and preventing DNA repair. O6-Benzylguanine induces tumor cell apoptosis. Antineoplastic activity.
|
-
- HY-W011518
-
|
2′-Deoxy-2′-fluoroguanosine
|
Influenza Virus
|
Infection
|
|
2′-Deoxy-2′-fluoroguanosine, a nucleoside analog, is a potent inhibitor of influenza virus strains, with an EC90 of <0.35 μM for influenza virus A and B strains. 2′-Deoxy-2′-fluoroguanosine significantly inhibits replication of influenza virus in the upper respiratory tract, resulting in amelioration of fever and nasal inflammation.
|
-
- HY-D1028
-
|
DiD perchlorate
|
Fluorescent Dye
|
Others
|
|
DiD is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins.
|
-
- HY-105584
-
-
- HY-120993
-
|
1,N6-Ethenoadenosine 5'-monophosphate sodium
1,N6-Etheno-AMP sodium; 1,N6-ε-AMP sodium
|
Fluorescent Dye
|
Others
|
|
1,N6-Ethenoadenosine 5'-monophosphate (1,N6-Etheno-AMP) sodium is a highly fluorescent analog of adenosine 5'-monophosphate (AMP). 1,N6-Ethenoadenosine 5'-monophosphate sodium is a powerful probe for systems involving adenosine 5'-monophosphate and can be detected at low concentration. 1,N6-Ethenoadenosine 5'-monophosphate sodium has long wavelength of excitation (250-300 nm), and emission at 415 nm. Storage: protect from light.
|
-
- HY-141422A
-
-
- HY-108525
-
|
Fluorobexarotene
|
RAR/RXR
|
Cancer
|
|
Fluorobexarotene (compound 20) is a potent retinoid-X-receptor (RXR) agonist, with a Ki value of 12 nM and an EC50 value of 43 nM for RXRα receptor. Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene.
|
-
- HY-114204
-
|
GSK8814
|
Epigenetic Reader Domain
|
Cancer
|
|
GSK8814 is a potent, selective, and ATAD2/2B bromodomain chemical probe and inhibitor, with a binding constant pKd=8.1 and a pKi=8.9 in BROMOscan. GSK8814 binds to ATAD2 and BRD4 BD1 with pIC50s of 7.3 and 4.6, respectively. GSK8814 shows 500-fold selectivity for ATAD2 over BRD4 BD1.
|
-
- HY-132822
-
-
- HY-139101
-
-
- HY-135326
-
-
- HY-P4237
-
-
- HY-138880
-
-
- HY-146588
-
|
NMDA receptor antagonist 4
|
iGluR
|
Neurological Disease
|
|
NMDA receptor antagonist 4 (IIc) is a uncompetitive, voltage-dependent, orally active NMDAR blocker, with an IC50 of 1.93 µM. NMDA receptor antagonist 4 shows a positive predicted blood-brain-barrier (BBB) permeability, and can be studied in Alzheimer's disease.
|
-
- HY-P1301
-
|
[Arg14,Lys15]Nociceptin
|
Opioid Receptor
|
Neurological Disease
|
|
[Arg14,Lys15]Nociceptin is a highly potent and selective NOP receptor (ORL1; OP4) agonist, with an EC50 of 1 nM. [Arg14,Lys15]Nociceptin displays high selectivity over opioid receptors, with IC50s of 0.32, 280, >10000 and 1500 nM for NOP, μ, δ and κ receptors, respectively.
|
-
- HY-15517A
-
|
KN-92 phosphate
|
Others
|
Cancer
|
|
KN-92 phosphate is an inactive derivative of KN-93, without CaM kinase inhibitory activity. KN-92 phosphate is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 is a cell-permeable, reversible and competitive CaMKII inhibitor.
|
-
- HY-P1301A
-
|
[Arg14,Lys15]Nociceptin TFA
|
Opioid Receptor
|
Neurological Disease
|
|
[Arg14,Lys15]Nociceptin TFA is a highly potent and selective NOP receptor (ORL1; OP4) agonist, with an EC50 of 1 nM. [Arg14,Lys15]Nociceptin TFA displays high selectivity over opioid receptors, with IC50s of 0.32, 280, >10000 and 1500 nM for NOP, μ, δ and κ receptors, respectively.
|
-
- HY-17422B
-
|
Acyclovir monophosphate
|
HSV
Antibiotic
|
Cancer
Infection
|
|
Acyclovir monophosphate is a potent anti-herpes simplex virus (HSV) agent. Acyclovir monophosphate blocks DNA synthesis through the inhibition of the viral DNA polymerase and terminates the chain elongation of the viral DNA. Acyclovir monophosphate shows antitumor activity.
|
-
- HY-153016
-
-
- HY-15517
-
|
KN-92
|
Others
|
Cancer
|
|
KN-92 is an inactive derivative of KN-93, without CaM kinase inhibitory activity. KN-92 is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 is a cell-permeable, reversible and competitive CaMKII inhibitor.
|
-
- HY-15517B
-
|
KN-92 hydrochloride
|
Others
|
Cancer
|
|
KN-92 hydrochloride is an inactive derivative of KN-93, without CaM kinase inhibitory activity. KN-92 hydrochloride is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93.
|
-
- HY-128995AS
-
-
- HY-34595
-
|
Pyrazoloadenine
|
RET
|
Cancer
|
|
Pyrazoloadenine is a potent RET (REarranged during Transfection) lung cancer oncoprotein inhibitor. Pyrazoloadenine shows anticancer activity.
|
-
- HY-101970
-
-
- HY-152559
-
-
- HY-154274
-
-
- HY-152557
-
-
- HY-154506
-
|
N2-Phenoxyacetylguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N2-Phenoxyacetylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-154361
-
|
TLR7 agonist 13
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
TLR7 agonist 13 is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-152430
-
|
8-Hydroxymethyl guanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Hydroxymethyl guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-154332
-
|
8-(Phenylmethoxy)guanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-(Phenylmethoxy)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-152652
-
|
5’(R)-C-Methylguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5’(R)-C-Methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-152478
-
|
3’-β-C-Ethynylguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-β-C-Ethynylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-101969
-
-
- HY-154719
-
-
- HY-122427
-
|
Xylocytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Xylocytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities.
|
-
- HY-152496
-
-
- HY-154111
-
|
8-(N-Boc-aminomethyl)guanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-(N-Boc-aminomethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-152673
-
|
9-(β-D-Xylofuranosyl)guanine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
9-(β-D-Xylofuranosyl)guanine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-152502
-
-
- HY-154255
-
-
- HY-77036
-
-
- HY-13770
-
-
- HY-76802
-
-
- HY-B0111
-
-
- HY-137883
-
-
- HY-152991
-
|
6-Deoxo-8-oxo-3’-deoxy-guanosine
|
Others
|
Others
|
|
2′-Deoxy-N-(2-furanylmethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-152993
-
|
2′-Deoxy-N-(2-furanylmethyl)guanosine
|
Others
|
Others
|
|
2′-Deoxy-N-(2-furanylmethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-W020098
-
-
- HY-W400159
-
-
- HY-W578275
-
-
- HY-152694
-
|
5-Vinylcytidine
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
5-Vinylcytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities.
|
-
- HY-152658
-
|
5-Phenylcytidine
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
5-Phenylcytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities.
|
-
- HY-W555551
-
-
- HY-D1617
-
|
BODIPY 500/510 C1, C12
|
Fluorescent Dye
|
Others
|
|
BODIPY 500/510 C1, C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the polar lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells. Maximum excitation/emission wavelength: 500/510 nm. Protect from light, stored at -20℃.
|
-
- HY-154482
-
|
N2-iso-Butyroyl-3’-O-methylguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N2-iso-Butyroyl-3’-O-methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-154448
-
|
3,5-Bis-O-(2,4-dichlorobenzyl)guanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3,5-Bis-O-(2,4-dichlorobenzyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-154336
-
|
N-[2-[4-(1-Methylethyl)phenoxy]acetyl]guanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N-[2-[4-(1-Methylethyl)phenoxy]acetyl]guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-154349
-
|
N2-iso-Butyroyl-2’-O-propargylguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N2-iso-Butyroyl-2’-O-propargylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-154549
-
|
3’-O-MOE-G(iBu)-2’-phosphoramidite
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-O-MOE-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-154484
-
|
3’-O-Me-G(iBu)-2’-phosphoramidite
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-O-Me-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-103248
-
|
Toyocamycin
Vengicide
|
IRE1
Fungal
Antibiotic
Apoptosis
CDK
|
Cancer
Infection
|
|
Toyocamycin (Vengicide) is an adenosine analog produced by Streptomyces diastatochromogenes, acts as an XBP1 inhibitor. Toyocamycin blocks RNA synthesis and ribosome function, and induces apoptosis. Toyocamycin affects IRE1α-XBP1 pathway, and inhibits XBP1 mRNA cleavage with an IC50 value of 80 nM with affecting IRE1α auto-phosphorylation. Toyocamycin specifically inhibits CDK9 with an IC50 value of 79 nM.
|
-
- HY-113431
-
|
Arabinosylhypoxanthine
Hypoxanthine, 9-beta-D-arabinofuranosyl-
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Arabinosylhypoxanthine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154551
-
-
- HY-152995
-
|
Confidential
|
Others
|
Others
|
|
Confidential is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154269
-
|
Confiden
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Confiden is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154115
-
-
- HY-152476
-
-
- HY-154735
-
|
N3-Allyluridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N3-Allyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents.
|
-
- HY-154270
-
|
Confident
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Confident is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154699
-
-
- HY-124092
-
|
Raluridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Raluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152988
-
|
N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine
|
Others
|
Others
|
|
N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-152992
-
|
7-Cyano-7-deaza-2'-deoxy guanosine
|
Others
|
Others
|
|
7-Cyano-7-deaza-2'-deoxy guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-154547
-
|
N2-iso-Butyroyl-3’-O-(methoxyethyl)guanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N2-iso-Butyroyl-3’-O-(methoxyethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-152665
-
-
- HY-152784
-
-
- HY-152394
-
-
- HY-154139
-
-
- HY-154524
-
-
- HY-154137
-
-
- HY-152446
-
-
- HY-152789
-
-
- HY-152787
-
-
- HY-152667
-
-
- HY-154150
-
-
- HY-154668
-
|
5'-Homocytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5'- Homocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W007791
-
|
Chloropurine riboside
6-Chloropurine riboside
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Chloropurine riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152970
-
|
7'-O-DMT-morpholino uracil
|
Others
|
Others
|
|
7'-O-DMT-morpholino uracil is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents.
|
-
- HY-152429
-
-
- HY-154614
-
-
- HY-16565
-
-
- HY-154698
-
|
5’-Homouridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5’-Homouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152617
-
|
4’-Thioinosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
4’-Thioinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154732
-
|
2-Thiopseudouridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Thiopseudouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W115186
-
-
- HY-112581
-
|
5-Methoxyuridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5-Methoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W602640
-
|
2'-Deoxyisoguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2'-Deoxyisoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W011079
-
|
5-Iodouridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5-Iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154242
-
|
8-Methylguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154535
-
|
Alpha-inosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Alpha-inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154734
-
-
- HY-154329
-
|
2-Deoxyuridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W244398
-
|
2-Thiocytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Thiocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W557556
-
-
- HY-154253
-
|
α-Azidothymidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
α-Azidothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W587829
-
|
4-Thiothymidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
4-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-131795
-
|
2-Methylthioadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Methylthioadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W576440
-
|
α-Cytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
α-Cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154536
-
|
Alpha-Guanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Alpha-Guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154413
-
-
- HY-152544
-
|
8-Allylthioguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Allylthioguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W609639
-
|
2’-Deoxyisocytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxyisocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154268
-
|
Confidential-2
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Confidential-2 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W009538
-
-
- HY-154670
-
|
5’-Homoadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5’-Homoadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154534
-
|
Alpha-Adenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Alpha-Adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W048500
-
|
2-Thiothymidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-151414
-
|
3'-Deoxyinosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3'-Deoxyinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-131792
-
|
2-Chloroinosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Chloroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W100215
-
|
5-Methylcyclocytidine hydrochloride
5-Methylcyclocytidine hydrochlorine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5-Methylcyclocytidine hydrochloride is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154217
-
-
- HY-154275
-
|
4’-Methylthymidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
4’-Methylthymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152488
-
-
- HY-W009163
-
|
5-Bromouridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5-Bromouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152545
-
|
N1,N2-Dimethyl-2’-O-methylguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N1,N2-Dimethyl-2’-O-methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-154350
-
|
5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-154606
-
|
2'-F-2'-ara-N2-ibu-dG Phosphoramidite
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2'-F-2'-ara-N2-ibu-dG Phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-W073825
-
|
N2-iso-Butyryl-2'-O-(2-methoxyethyl)guanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N2-iso-Butyryl-2'-O-(2-methoxyethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-154421
-
|
2’,5’-Dideoxyuridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’,5’-Dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-149072
-
|
TLR7 agonist 11
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
TLR7 agonist 11 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-N8525
-
|
3'-O-Acetylthymidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3'-O-Acetylthymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-149071
-
|
TLR7 agonist 10
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
TLR7 agonist 10 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152656
-
|
2-Hydrazinyl-adenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Hydrazinyl-adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154127
-
-
- HY-152510
-
|
5-(Aminomethyl)uridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5-(Aminomethyl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154285
-
-
- HY-105006
-
|
Spongosine
2-Methoxyadenosine; 2-O-Methylisoguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Spongosine (2-Methoxyadenosine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154474
-
|
3’,4-Dideoxyuridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’,4-Dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W013259
-
-
- HY-152375
-
|
8-Hydroxy-xyloguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Hydroxy-xyloguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152327
-
-
- HY-W130466
-
|
N4-Methylcytidine
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
N4-Methylcytidine (Nsc518744) is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities.
|
-
- HY-130806
-
|
Dihydrodeoxyuridine
H2dUrd
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Dihydrodeoxyuridine (H2dUrd) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152382
-
-
- HY-152602
-
|
1,3'-Dimethylguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
1,3'-Dimethylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154434
-
-
- HY-152441
-
|
2-Aminomethyl adenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Aminomethyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154131
-
|
3-Deaza-xylouridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3-Deaza-xylouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W014306
-
|
2',3'-Dideoxyuridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2',3'-Dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W020361
-
|
2'-C-Ethynyluridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2'-C-Ethynyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154273
-
-
- HY-W412546
-
|
3’-O-Methyluridine
4-[1-[(2-Methylphenyl)methyl]benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-O-Methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152321
-
|
5-Hydroxy-arabinouridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5-Hydroxy-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-101904
-
-
- HY-154548
-
-
- HY-154507
-
-
- HY-139167
-
-
- HY-B0600
-
-
- HY-131100
-
-
- HY-16445
-
-
- HY-154537
-
|
3’-O-Methyl inosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-O-Methyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154738
-
-
- HY-154616
-
-
- HY-152474
-
|
2’-β-C-Ethynylcytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-β-C-Ethynylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152969
-
-
- HY-154317
-
-
- HY-152985
-
|
3’-Azido-3’-deoxy-4-deoxyuridine
|
Others
|
Others
|
|
6-Chloro-N1-(trimethylsilylethoxymethyl)pseudouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents.
|
-
- HY-154356
-
-
- HY-W556301
-
-
- HY-W108399
-
-
- HY-152360
-
-
- HY-154256
-
|
5-(2-Azidoethyl)uridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5-(2-Azidoethyl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152475
-
|
2’-β-C-Ethynyladenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-β-C-Ethynyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154530
-
|
DMTr-TNA-C(Bz)-amidite
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
DMTr-TNA-C(Bz)-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152613
-
|
N2-Ethylguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N2-Ethylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152528
-
-
- HY-154151
-
-
- HY-154620
-
|
2′-O-Hexadecyl-adenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2′-O-Hexadecyl-adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154674
-
|
N1-Allylpseudouridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N1-Allylpseudouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154626
-
|
2’-O-Hexadecanyl guanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-O-Hexadecanyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152714
-
-
- HY-154109
-
|
N1-Aminopseudouridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N1-Aminopseudouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154461
-
-
- HY-154528
-
-
- HY-W550365
-
-
- HY-154110
-
|
N3-Aminopseudouridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N3-Aminopseudouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154453
-
|
4-Deoxy-xylo-uridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
4-Deoxy-xylo-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154640
-
-
- HY-154187
-
-
- HY-152406
-
-
- HY-W128112
-
|
1-(a-D-ribofuranosyl)uracil
alpha-D-Ribofuranoside,2,4(1H,3H)-pyrimidinedione-1
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
1-(a-D-ribofuranosyl)uracil is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152822
-
-
- HY-152526
-
-
- HY-137589
-
|
N6-Dimethyldeoxyadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N6-Dimethyldeoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154398
-
|
5-Aza-xylo-cytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5-Aza-xylo-cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154621
-
|
3’-O-Hexadecanyl adenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-O-Hexadecanyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152547
-
-
- HY-154464
-
-
- HY-152344
-
|
2’-β-C-Methyl inosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-β-C-Methyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W130204
-
|
N-Acetyl-2′-deoxycytidine
N4-Acetyl-2'-deoxycytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N-Acetyl-2′-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152483
-
-
- HY-154553
-
|
3’,5’-Di-O-acetylthymidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’,5’-Di-O-acetylthymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152411
-
|
3’-Beta-C-Methyl-inosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Beta-C-Methyl-inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W114787
-
-
- HY-W552067
-
-
- HY-152608
-
|
N6-iso-Propyladenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N6-iso-Propyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154354
-
-
- HY-20142
-
-
- HY-152464
-
|
N1-Methyl-arabinoadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N1-Methyl-arabinoadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154736
-
-
- HY-152598
-
|
N1-Methylxylo-guanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N1-Methylxylo-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152300
-
-
- HY-154722
-
-
- HY-152447
-
|
3’-beta-C-Ethynyl inosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-beta-C-Ethynyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152459
-
-
- HY-152625
-
|
2’-Beta-C-Ethynyl inosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Beta-C-Ethynyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154480
-
-
- HY-15680
-
-
- HY-139625
-
-
- HY-77644
-
|
5'-Deoxy-5'-iodouridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5'-Deoxy-5'-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154737
-
-
- HY-154717
-
|
2-Deoxy-2’-fluoroisocytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Deoxy-2’-fluoroisocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152743
-
|
8-Aza-7-deazguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Aza-7-deazguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-482934
-
|
2’-Deoxy-2’-fluoroinosine
2'-Fluoro-2'-deoxyinosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154559
-
-
- HY-152351
-
|
8-Bromo-3’-deoxyguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Bromo-3’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154001
-
-
- HY-152480
-
-
- HY-149220
-
-
- HY-W011168
-
|
8-Bromo-2'-deoxyguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Bromo-2'-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154114
-
|
2′-Deoxy-2-iodoadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2′-Deoxy-2-iodoadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W013330
-
|
3′-Deoxyguanosine
Guanosine, 3'-deoxy-
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3′-Deoxyguanosine (Guanosine, 3'-deoxy-) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152295
-
|
3’-Deoxy-2’-thiouridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Deoxy-2’-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W141338
-
|
2′-Bromo-2′-deoxyuridine
2'-Bromo-2'-deoxy-D-uridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2′-Bromo-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154397
-
-
- HY-154324
-
|
2′-Deoxy-2-thiouridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2′-Deoxy-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152463
-
-
- HY-154241
-
|
8-Methyl-2’-deoxyadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Methyl-2’-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154347
-
|
5′-Deoxy-5′-iodothymidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5′-Deoxy-5′-iodothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154491
-
|
5’-Deoxy-5-methyluridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5’-Deoxy-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154011
-
|
8-Amino-2′-deoxyadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Amino-2′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154153
-
|
2-Methyl-2’-deoxyadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Methyl-2’-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154088
-
|
3′-Deoxy-3′-iodothymidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3′-Deoxy-3′-iodothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-138953A
-
|
Epiboxidine hydrochloride
|
nAChR
|
Neurological Disease
|
|
Epiboxidine hydrochloride is a potent and selective neural nAChR agonist with Kis of 0.46 nM and 1.2 nM for rat and human α4β2 nAChRs, respectively. Epiboxidine hydrochloride is a methylisoxazole analog of the alkaloid Epibatidine, and is also an analog of another nAChR agonist, ABT 418.
|
-
- HY-W460267
-
|
N2,2'-O-Dimethylguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N2,2'-O-Dimethylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-149160
-
|
5′-Amino-5′-deoxythymidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5′-Amino-5′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152367
-
|
8-Hydroxy-3’-deoxyguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Hydroxy-3’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154364
-
-
- HY-154327
-
|
DMTr-dH2U-amidite
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
DMTr-dH2U-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154054
-
|
5′-Azido-5′-deoxyadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5′-Azido-5′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154214
-
-
- HY-154025
-
|
8-Azido-2′-deoxyadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Azido-2′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154589
-
-
- HY-154520
-
|
2-Chloro-3′-deoxyadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Chloro-3′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154467
-
|
2′-Deoxy-6-thioinosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2′-Deoxy-6-thioinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154243
-
|
8-Methyl-2’-deoxyguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Methyl-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152354
-
-
- HY-154200
-
|
3’-Deoxy-5-methycytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Deoxy-5-methycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-138953
-
|
Epiboxidine
|
nAChR
|
Neurological Disease
|
|
Epiboxidine is a potent and selective neural nAChR agonist with Kis of 0.46 nM and 1.2 nM for rat and human α4β2 nAChRs, respectively. Epiboxidine is a methylisoxazole analog of the alkaloid Epibatidine, and is also an analog of another nAChR agonist, ABT 418.
|
-
- HY-154540
-
|
Alpha-5-Methyluridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Alpha-5-Methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152465
-
-
- HY-154554
-
|
3’,5’-Di-O-benzoyl thymidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’,5’-Di-O-benzoyl thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154215
-
-
- HY-154087
-
|
3′-Bromo-3′-deoxythymidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3′-Bromo-3′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152519
-
-
- HY-154443
-
|
Rev dC(Bz)-5'-amidite
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Rev dC(Bz)-5'-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154300
-
-
- HY-154405
-
|
5’-Azido-5’-deoxyuridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5’-Azido-5’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W154172
-
|
2′-Chloro-2′-deoxyuridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2′-Chloro-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154666
-
|
3’-Azido-3’-deoxyinosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Azido-3’-deoxyinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154470
-
|
8-Aza-2’-deoxyguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Aza-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154740
-
|
3′-Chloro-3′-deoxythymidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3′-Chloro-3′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W039275
-
|
5'-Deoxy-5'-iodoguanosine
5'-Iodo-5'-deoxyguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5'-Deoxy-5'-iodoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W006957
-
|
N6-(2-Hydroxyethyl)adenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N6-(2-Hydroxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W128788A
-
-
- HY-154692
-
|
2′-Deoxy-5-methylisocytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2′-Deoxy-5-methylisocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154294
-
|
N1-Methyl ara-uridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N1-Methyl ara-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154120
-
|
6-Aza-2'-deoxyuridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
6-Aza-2'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W251781
-
|
4-Thio-2’-deoxyuridine
2′-Deoxy-4-thiouridine; 4-Thiodeoxyuridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
4-Thio-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W013052
-
|
8-Bromo-2'-deoxyadenosine
8-Bromo-9-(2-deoxypentofuranosyl)-9H-purin-6-amine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154399
-
|
5-Aza-3’-deoxycytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5-Aza-3’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154351
-
-
- HY-154483
-
-
- HY-150697
-
|
HIV-1 inhibitor-44
|
HIV
|
Others
|
|
HIV-1 inhibitor-44 (compound 11l) is a HIV-1 reverse transcriptase inhibitor. HIV-1 inhibitor-44 shows inhibitory activity against wild-type HIV-1 strain with an EC50 value of 0.209 μM.
|
-
- HY-150056
-
-
- HY-151119
-
|
Anticancer agent 78
|
Cytochrome P450
|
Cancer
|
|
Anticancer agent 78 is a potent anticancer agent. Anticancer agent 78 shows cytotoxicity. Anticancer agent 78 exhibits anti-aromatase activity with an IC50 value of 0.9 µM. Anticancer agent 78 has the potential for the research of breast cancer.
|
-
- HY-150568
-
|
SIRT1/2/3-IN-1
|
Sirtuin
|
|
|
SIRT1/2/3-IN-1 (compound 10) is a highly potent, selective and cell permeable inhibitor of SIRT1, SIRT2 and SIRT3 with IC50s of 0.54, 0.253, and 0.72 μM, respectively. SIRT1/2/3-IN-1 (compound 10) can be used for research of cancer.
|
-
- HY-154232
-
-
- HY-154012
-
-
- HY-154248
-
|
2’-Deoxy-3’,2-anhydrouridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-3’,2-anhydrouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154147
-
|
2’-Deoxy-N1-methylguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-N1-methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154624
-
-
- HY-152662
-
-
- HY-154038
-
-
- HY-154392
-
|
2-Chloro-2’-deoxy inosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Chloro-2’-deoxy inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154533
-
|
3’-O-Acetyl-2’-deoxyuridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-O-Acetyl-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154456
-
-
- HY-154237
-
|
5’-O-DMTr-3’-deoxyuridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5’-O-DMTr-3’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154556
-
-
- HY-152377
-
|
5-Hydroxy-2’-O-methyluridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5-Hydroxy-2’-O-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154697
-
|
3-epi-Azido-3-deoxythymidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3-epi-Azido-3-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152640
-
|
5-Fluoro-4’-thio-cytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5-Fluoro-4’-thio-cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154400
-
|
5-Aza-3’-beta-methylcytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5-Aza-3’-beta-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154239
-
-
- HY-152593
-
|
3’-Deoxy-N1-methylguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Deoxy-N1-methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152379
-
-
- HY-154374
-
-
- HY-W603690
-
-
- HY-W550918
-
|
5-Bromo-2’-O-methyluridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5-Bromo-2’-O-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154333
-
-
- HY-W560803
-
-
- HY-154625
-
-
- HY-154569
-
-
- HY-77645
-
|
4',5'-Didehydro-5'-deoxyuridine
1-(5-Deoxy-beta-D-erythro-pent-4-enofuranosyl)uracil
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
4',5'-Didehydro-5'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154564
-
-
- HY-154289
-
-
- HY-154560
-
-
- HY-152516
-
-
- HY-154420
-
-
- HY-154026
-
-
- HY-152499
-
|
1-Methyl-2'-O-methylinosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
1-Methyl-2'-O-methylinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154303
-
-
- HY-154204
-
-
- HY-152996
-
-
- HY-154602
-
-
- HY-152590
-
|
3’-Deoxy-N6-methyladenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Deoxy-N6-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154372
-
|
2′,5′-Dideoxy-5′-iodouridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2′,5′-Dideoxy-5′-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154496
-
|
2’-Deoxy-N3-methylcytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-N3-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154558
-
|
2′-Deoxy-6-O-methylinosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2′-Deoxy-6-O-methylinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152316
-
-
- HY-104039
-
-
- HY-152763
-
-
- HY-154052
-
-
- HY-W415119
-
|
2',3'-Di-O-acetyl-D-uridine
acetic acid 4-acetoxy-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydrofuran-3-yl ester
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2',3'-Di-O-acetyl-D-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154126
-
-
- HY-152307
-
|
2-Chloro-N6-methyladenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Chloro-N6-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154293
-
|
3’-Deoxy-N6-ethyladenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Deoxy-N6-ethyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-137548
-
-
- HY-154055
-
-
- HY-154590
-
-
- HY-152577
-
-
- HY-154510
-
|
2’-Deoxy-N4-methylcytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-N4-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152638
-
|
2-Amino-3’-O-methyladenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Amino-3’-O-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152588
-
|
3’-Deoxy-N1-methyladenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Deoxy-N1-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W347492
-
|
6-O-Methyldeoxyguanosine
O6-Methyl-2′-deoxyguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
O6-Methyldeoxy guanosine; DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154563
-
-
- HY-112582S
-
|
N1-Methylpseudouridine-d3
1-Methylpseudouridine-d3; N1-methyl-pseudouridine-d3
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N1-Methylpseudouridine-d3 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-101937A
-
|
(±)-ANAP
|
Fluorescent Dye
|
Others
|
|
(±)-ANAP is the unnatural amino acid analog of prodan, acts as a fluorescent probes, and enhances environmental sensitivity.
|
-
- HY-101937C
-
-
- HY-15156
-
-
- HY-B1011
-
|
Edoxudine
EUDR
|
Bacterial
|
Infection
|
|
Edoxudine is an antiviral drug, is an analog of thymidine, shows effectiveness against herpes simplex virus.
|
-
- HY-103185
-
|
CCPA
2-Chloro-N6-cyclopentyladenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
CCPA (2-Chloro-N6-cyclopentyladenosine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W025438
-
-
- HY-154544
-
-
- HY-154466
-
-
- HY-W357202
-
|
7’-OH-N-trityl morpholinothymine
PMO Thymidine Precusor
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
7’-OH-N-trityl morpholinothymine (PMO Thymidine Precusor) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152397
-
-
- HY-154142
-
-
- HY-152317
-
|
5-Methyl-2-thio-xylo-uridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5-Methyl-2-thio-xylo-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152514
-
-
- HY-154136
-
-
- HY-154201
-
|
3’-Deoxy-O6-methyl inosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Deoxy-O6-methyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W013728
-
-
- HY-154568
-
-
- HY-148019
-
-
- HY-154472
-
|
N4-Ethyl-2’-deoxycytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N4-Ethyl-2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154233
-
-
- HY-154428
-
-
- HY-154130
-
-
- HY-154292
-
|
3’-Deoxy-N1-Methyl inosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Deoxy-N1-Methyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154262
-
|
N6-Ethyl-2’-deoxyadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N6-Ethyl-2’-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W570891
-
-
- HY-152635
-
-
- HY-152811
-
-
- HY-152467
-
-
- HY-154468
-
-
- HY-154129
-
-
- HY-154348
-
-
- HY-154296
-
-
- HY-154018
-
|
N4-Benzoyl-5-methylcytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N4-Benzoyl-5-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154161
-
-
- HY-152497
-
|
3’-β-C-Methyl-2-thiouridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-β-C-Methyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154600
-
|
N4-Benzoyl-3’-deoxycytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N4-Benzoyl-3’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152442
-
-
- HY-152651
-
-
- HY-154430
-
-
- HY-W411295
-
-
- HY-W010681A
-
-
- HY-48973
-
-
- HY-W394419
-
-
- HY-152322
-
-
- HY-154462
-
-
- HY-154373
-
-
- HY-154138
-
-
- HY-152501
-
|
8-Chloro-2’-O-methyl inosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Chloro-2’-O-methyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152500
-
|
4-Deoxy-3’-β-C-methyluridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
4-Deoxy-3’-β-C-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-49200
-
-
- HY-154141
-
-
- HY-154128
-
-
- HY-154202
-
-
- HY-154495
-
|
N3-Methyl-5-methyluridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N3-Methyl-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W377454
-
-
- HY-154330
-
-
- HY-W048512
-
-
- HY-154143
-
-
- HY-154432
-
|
N1-Methyl-2’-deoxyinosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N1-Methyl-2’-deoxyinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152466
-
-
- HY-W047393
-
-
- HY-154231
-
-
- HY-154081
-
-
- HY-154457
-
-
- HY-154064
-
-
- HY-154198
-
-
- HY-154257
-
-
- HY-154529
-
-
- HY-154406
-
|
2′-Deoxy-N-methylguanosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-N2-methylguanosine, DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154508
-
-
- HY-154252
-
-
- HY-154173
-
-
- HY-154261
-
-
- HY-154813
-
-
- HY-152675
-
-
- HY-152624
-
|
N6-Methyl-4’-thio-adenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N6-Methyl-4’-thio-adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152508
-
-
- HY-154323
-
-
- HY-154566
-
-
- HY-152606
-
-
- HY-154516
-
-
- HY-152621
-
|
N6-Ethyl-4’-thio-adenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N6-Ethyl-4’-thio-adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152413
-
-
- HY-154357
-
-
- HY-152461
-
-
- HY-154314
-
-
- HY-154358
-
-
- HY-49199
-
-
- HY-154458
-
-
- HY-152648
-
-
- HY-154481
-
-
- HY-154414
-
-
- HY-152324
-
-
- HY-154488
-
-
- HY-154565
-
-
- HY-154395
-
-
- HY-W100234
-
-
- HY-154297
-
-
- HY-145791
-
|
Dideoxycytidinene
2′,3′-Didehydro-2′,3′-dideoxycytidine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Dideoxycytidinene (2′,3′-Didehydro-2′,3′-dideoxycytidine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-W128788
-
|
2’-Deoxy-2’-fluoro-b-D-arabinocytidine
4-amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)pyrimidin-2(1H)-one
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-b-D-arabinocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154019
-
-
- HY-152494
-
-
- HY-154082
-
-
- HY-103273
-
|
Muristerone A
|
Others
|
Others
|
|
Muristerone A is a phytoecdysteroid analog of ecdysone and a potent agonist of ecdysteroid receptor with a Kd of 1 nM.
|
-
- HY-W005627
-
-
- HY-P1445
-
-
- HY-13760
-
-
- HY-118122
-
-
- HY-154417
-
-
- HY-154170
-
-
- HY-152332
-
-
- HY-154418
-
-
- HY-154595
-
-
- HY-154344
-
-
- HY-W342664
-
-
- HY-154609
-
-
- HY-154230
-
-
- HY-152337
-
-
- HY-152664
-
-
- HY-154144
-
-
- HY-152330
-
-
- HY-152302
-
-
- HY-154396
-
-
- HY-152362
-
-
- HY-154599
-
-
- HY-W010917
-
-
- HY-154288
-
-
- HY-154066
-
-
- HY-W054074
-
-
- HY-154410
-
-
- HY-134337
-
-
- HY-154573
-
-
- HY-154642
-
-
- HY-152359
-
-
- HY-152335
-
-
- HY-154320
-
-
- HY-154513
-
-
- HY-152482
-
-
- HY-152705
-
-
- HY-154156
-
-
- HY-152653
-
-
- HY-154578
-
|
N1-Methyl-2’-deoxyadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N1-Methyl-2’-deoxyadenosine, DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152457
-
-
- HY-W551974
-
-
- HY-154415
-
-
- HY-154402
-
-
- HY-154213
-
-
- HY-154085
-
-
- HY-W048487
-
|
N6-Benzoyl-7’-OH-morpholino adenine
N6-Benzoyl-7'-OH-Morpholino adenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N6-Benzoyl-7’-OH-morpholino adenine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152455
-
-
- HY-152611
-
-
- HY-152356
-
-
- HY-154190
-
-
- HY-154259
-
-
- HY-152733
-
-
- HY-154271
-
|
TLR7 agonist 12
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
TLR7 agonist 12 (example 20) is a TLR7 agonist, also is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154119
-
-
- HY-154346
-
-
- HY-154121
-
-
- HY-W397503
-
|
5’-O-DMTr-5-iodo-2’-deoxyuridine
2'-Deoxy-5'-O-DMT-5-iodouridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5’-O-DMTr-5-iodo-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154167
-
-
- HY-152566
-
-
- HY-154526
-
-
- HY-149070
-
-
- HY-154218
-
-
- HY-152509
-
-
- HY-152618
-
-
- HY-152424
-
-
- HY-154305
-
-
- HY-152627
-
-
- HY-154545
-
-
- HY-154473
-
-
- HY-152563
-
-
- HY-154291
-
-
- HY-154133
-
-
- HY-154059
-
-
- HY-131818
-
|
5'-Amino-5'-deoxyadenosine
NH2dAdo; Nsc 238990
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5'-Amino-5'-deoxyadenosine (NH2dAdo; Nsc 238990) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152340
-
-
- HY-152507
-
-
- HY-154465
-
-
- HY-154319
-
-
- HY-152633
-
-
- HY-154394
-
-
- HY-152642
-
-
- HY-154407
-
-
- HY-154511
-
-
- HY-154295
-
-
- HY-154159
-
-
- HY-154550
-
-
- HY-154391
-
-
- HY-131847
-
|
2,6-Dichloro-2',3',5'-triacetyl-purine riboside
2,6-Dichloro-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2,6-Dichloro-2',3',5'-triacetyl-purine riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-152489
-
-
- HY-154370
-
-
- HY-154308
-
-
- HY-152403
-
-
- HY-152504
-
-
- HY-154579
-
-
- HY-152626
-
-
- HY-154355
-
-
- HY-154492
-
-
- HY-154531
-
-
- HY-154203
-
-
- HY-152976
-
-
- HY-154132
-
-
- HY-154246
-
-
- HY-152311
-
-
- HY-154404
-
-
- HY-154345
-
-
- HY-154134
-
-
- HY-154158
-
-
- HY-154306
-
-
- HY-W048504
-
-
- HY-154238
-
-
- HY-150144
-
-
- HY-B0191
-
-
- HY-P4223
-
-
- HY-P1506
-
-
- HY-112639
-
-
- HY-145977
-
-
- HY-32348
-
-
- HY-13742
-
|
Ropidoxuridine
IPdR
|
Others
|
Cancer
|
|
Ropidoxuridine (IPdR) is a novel orally available, halogenated thymidine analog and is a potential radiosensitizer for use in human tumors.
|
-
- HY-135402
-
-
- HY-145974
-
-
- HY-150257
-
-
- HY-154660
-
-
- HY-154266
-
-
- HY-152484
-
-
- HY-154205
-
-
- HY-154235
-
-
- HY-154371
-
-
- HY-152486
-
-
- HY-152481
-
-
- HY-154408
-
-
- HY-41793
-
-
- HY-W457757
-
-
- HY-I0100
-
-
- HY-152634
-
-
- HY-154307
-
-
- HY-W357201
-
|
N4-Benzoyl-7’-OH-N-trityl morpholino cytosine
N-[1-(6-Hydroxymethyl-4-trityl-morpholin-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-benzamide
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N4-Benzoyl-7’-OH-N-trityl morpholino cytosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154050
-
-
- HY-154331
-
-
- HY-154343
-
-
- HY-152647
-
-
- HY-134315
-
|
8-Nitroguanosine
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
8-Nitroguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-152352
-
-
- HY-152978
-
|
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine
|
Others
|
Others
|
|
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities.
|
-
- HY-152492
-
-
- HY-W555976
-
-
- HY-W564313
-
-
- HY-154000
-
-
- HY-154557
-
-
- HY-154382
-
-
- HY-W357200
-
|
N6-Benzoyl-7’-OH-N-trityl morpholino adenine
N-[9-(6-Hydroxymethyl-4-trityl-morpholin-2-yl)-9H-purin-6-yl]-benzamide
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N6-Benzoyl-7’-OH-N-trityl morpholino adenine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154234
-
-
- HY-154376
-
-
- HY-W342904
-
|
2’-O-Methyl-5’-O-DMTr-5-iodouridine
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-5-iodo-2'-O-methyl-uridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-O-Methyl-5’-O-DMTr-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154304
-
-
- HY-154429
-
-
- HY-154612
-
-
- HY-154684
-
-
- HY-154258
-
|
Rev 2’-O-MOE-5MeU-5’-amidite
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Rev 2’-O-MOE-5MeU-5’-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154677
-
-
- HY-154123
-
-
- HY-154263
-
-
- HY-154567
-
-
- HY-154575
-
-
- HY-154175
-
-
- HY-154086
-
-
- HY-154437
-
-
- HY-154779
-
-
- HY-154360
-
-
- HY-152831
-
-
- HY-154442
-
-
- HY-154037
-
-
- HY-152571
-
-
- HY-154514
-
-
- HY-154309
-
-
- HY-154667
-
-
- HY-154251
-
-
- HY-154160
-
-
- HY-154605
-
-
- HY-154267
-
-
- HY-154729
-
-
- HY-152575
-
-
- HY-154469
-
-
- HY-152569
-
-
- HY-154024
-
-
- HY-154148
-
-
- HY-154604
-
-
- HY-154240
-
-
- HY-152350
-
-
- HY-152994
-
-
- HY-152570
-
-
- HY-152555
-
-
- HY-W553730
-
-
- HY-W395015
-
-
- HY-152567
-
-
- HY-152660
-
-
- HY-154587
-
-
- HY-W354644
-
-
- HY-154546
-
-
- HY-137406
-
|
1,2'-O-Dimethylguanosine
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
1,2'-O-Dimethylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-W018604
-
-
- HY-154325
-
-
- HY-154499
-
-
- HY-154220
-
-
- HY-154525
-
-
- HY-152998
-
-
- HY-152655
-
-
- HY-154077
-
-
- HY-152610
-
|
3′-C-Methylguanosine
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
3′-C-Methylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-154454
-
-
- HY-154478
-
-
- HY-43426A
-
-
- HY-152619
-
-
- HY-154588
-
-
- HY-152517
-
|
8-(Methylthio)guanosine
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
8-(Methylthio)guanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-154680
-
-
- HY-154463
-
-
- HY-154727
-
-
- HY-W559353
-
-
- HY-152663
-
-
- HY-154541
-
-
- HY-154517
-
-
- HY-154363
-
-
- HY-152587
-
-
- HY-154224
-
-
- HY-154682
-
-
- HY-154489
-
-
- HY-154723
-
-
- HY-154326
-
-
- HY-154135
-
-
- HY-152568
-
-
- HY-152573
-
-
- HY-152404
-
-
- HY-154236
-
-
- HY-154290
-
-
- HY-154552
-
-
- HY-154647
-
-
- HY-154542
-
-
- HY-23790
-
-
- HY-W565157
-
-
- HY-100960
-
|
Dioctanoylglycol
Ethylene glycol dicaprylate; Ethylene glycol dioctanoate; Ethylenedioctanoate
|
DGK
|
Cardiovascular Disease
|
|
Dioctanoylglycol (Ethylene glycol dicaprylate), a diacylglycerol analog, is a diacylglycerol kinase (DGK) inhibitor (Ki of 58 μM).
|
-
- HY-111757
-
-
- HY-B2031
-
-
- HY-101263
-
-
- HY-145977A
-
-
- HY-32339
-
-
- HY-101541
-
-
- HY-17365
-
-
- HY-13565
-
|
Becatecarin
NSC 655649; BMS 181176; BMY 27557
|
Topoisomerase
|
Cancer
|
|
Becatecarin is a rebeccamycin analog with antitumor effects. Becatecarin intercalates into DNA and inhibites the catalytic activity of topoisomerases I/II.
|
-
- HY-145974A
-
-
- HY-101744
-
-
- HY-130836
-
|
LpxH-IN-AZ1
|
Bacterial
|
Infection
|
|
LpxH-IN-AZ1, a sulfonyl piperazine compound, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. LpxH-IN-AZ1 is a potent inhibitor of Klebsiella pneumoniae LpxH with IC50 of 0.36 μM .
|
-
- HY-P3728
-
-
- HY-16339
-
|
N3PT
N3-pyridyl thiamine
|
Transketolase
|
Cancer
|
|
N3PT (N3-pyridyl thiamine) is a potent and selective transketolase inhibitor. N3PT is pyrophosphorylated and then binds to transketolase with an Kd value of 22 nM (Apo-TK, transketolase lacking bound thiamine).
|
-
- HY-108537
-
-
- HY-147964
-
-
- HY-105268
-
|
AzddMeC
CS-92
|
HIV
Reverse Transcriptase
Nucleoside Antimetabolite/Analog
|
Infection
|
|
AzddMeC (CS-92) is an antiviral nucleoside analogue and a potent potent, selective and orally active HIV-1 reverse transcriptase and HIV-1 replication inhibitor. In HIV-1-infected human PBM cells and HIV-1-infected human macrophages, the EC50 values of AzddMeC are 9 nM and 6 nM, respectively.
|
-
- HY-147965
-
-
- HY-143301
-
|
Topoisomerase I inhibitor 4
|
Topoisomerase
|
Cancer
|
|
Topoisomerase I inhibitor 4 (compound 7a) is a topoisomerase I inhibitor. Topoisomerase I inhibitor 4 inhibits HepG2, A549, MCF-7 and HeLa cancer cells proliferation with IC50s of 1.20, 2.09, 1.56 and 1.92 μM, respectively. Topoisomerase I inhibitor 4 can be used for the research of cancer.
|
-
- HY-W556276
-
-
- HY-154582
-
-
- HY-152542
-
|
8-Allylthioadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Allylthioadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
|
-
- HY-154023
-
-
- HY-W394793
-
-
- HY-W340190
-
|
2’-O-Methyl-5-iodouridine
5-Iodo-2'-O-methyluridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
|
-
- HY-154594
-
-
- HY-154725
-
-
- HY-154366
-
-
- HY-154057
-
-
- HY-154385
-
-
- HY-154561
-
-
- HY-154340
-
-
- HY-154264
-
-
- HY-154424
-
-
- HY-W008552
-
|
2-Iodoadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Iodoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
|
-
- HY-154683
-
-
- HY-154610
-
-
- HY-154583
-
-
- HY-154412
-
-
- HY-154622
-
-
- HY-154206
-
-
- HY-W045998
-
-
- HY-154543
-
-
- HY-152742
-
|
8-(N,N-Dimethylaminomethyl)guanosine
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
8-(N,N-Dimethylaminomethyl)guanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-154571
-
-
- HY-154721
-
-
- HY-154383
-
-
- HY-154720
-
-
- HY-154117
-
-
- HY-154276
-
-
- HY-154284
-
-
- HY-154223
-
-
- HY-154607
-
-
- HY-49198
-
-
- HY-154381
-
-
- HY-154423
-
-
- HY-154449
-
-
- HY-152636
-
|
2-Cyanomethylthioadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Cyanomethylthioadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
|
-
- HY-154592
-
-
- HY-154042
-
-
- HY-154627
-
-
- HY-154061
-
-
- HY-152834
-
|
8-Methoxyadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Methoxyadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
|
-
- HY-154302
-
-
- HY-154298
-
-
- HY-134317
-
|
8-Azidoadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Azidoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
|
-
- HY-152637
-
|
2-Benzylthioadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Benzylthioadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
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- HY-154359
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-
- HY-W013195
-
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8-Bromoadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Bromoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
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-
- HY-154056
-
-
- HY-152310
-
-
- HY-154377
-
-
- HY-W402064
-
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N-Acetyladenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N-Acetyladenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
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- HY-152979
-
-
- HY-154375
-
-
- HY-154045
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-
- HY-43426
-
-
- HY-154512
-
-
- HY-152347
-
-
- HY-W011548
-
|
2-Aminoadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Aminoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
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-
- HY-W601637
-
-
- HY-154222
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-
- HY-114673
-
-
- HY-13727
-
|
Pixantrone free base
BBR 2778 free base
|
Topoisomerase
|
Cancer
|
|
Pixantrone (BBR 2778 (free base)), a mitoxantrone analog, is a topoisomerase II inhibitor and DNA intercalator, with anti-tumor activity.
|
-
- HY-145009
-
|
SN-008
|
STING
|
Others
|
|
SN-008, a less active SN-011 analog, can be used as a negative control.
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-
- HY-76801
-
-
- HY-W015424
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-
- HY-145913
-
-
- HY-101006
-
-
- HY-125828
-
-
- HY-121608
-
|
Lumiflavin
Lumiflavine
|
Fluorescent Dye
|
Others
|
|
Lumiflavin (Lumiflavine), a riboflavine analog, can be used to detect riboflavine uptake. Storage: protect from light.
|
-
- HY-P0315
-
|
Crosstide
|
Akt
|
Others
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|
Crosstide is a peptide analog of glycogen synthase kinase α/β fusion protein sequence which is a substrate for Akt.
|
-
- HY-125699
-
|
Ochratoxin C
|
Fungal
|
Infection
|
|
Ochratoxin C is the ethyl ester analog of ochratoxin A, a mycotoxin produced by A. ochraceus, A. carbonarius, and P. verrucosum that is commonly found as a food contaminant.
|
-
- HY-W555583
-
-
- HY-154089
-
-
- HY-154221
-
-
- HY-152348
-
-
- HY-154601
-
-
- HY-154555
-
-
- HY-154384
-
-
- HY-44220
-
-
- HY-152835
-
|
8-(Methylamino)adenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-(Methylamino)adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
|
-
- HY-154145
-
-
- HY-128139
-
|
2'-C-Methylguanosine
2'-C-beta-Methylguanosine
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2'-C-Methylguanosine (2'-C-beta-Methylguanosine) is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
|
-
- HY-152532
-
-
- HY-154254
-
|
2-Diethoxymethyl adenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Diethoxymethyl adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
|
-
- HY-154439
-
-
- HY-154416
-
-
- HY-154260
-
-
- HY-154342
-
-
- HY-154490
-
-
- HY-152328
-
-
- HY-154328
-
-
- HY-154450
-
-
- HY-W008048
-
|
2',3'-O-Isopropylideneadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2',3'-O-Isopropylideneadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
|
-
- HY-154315
-
-
- HY-152531
-
-
- HY-154654
-
-
- HY-154154
-
-
- HY-154229
-
-
- HY-154523
-
|
2-(4-Cyanobenzyl)thioadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-(4-Cyanobenzyl)thioadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
|
-
- HY-154681
-
-
- HY-154611
-
-
- HY-154386
-
-
- HY-154686
-
-
- HY-154562
-
-
- HY-154186
-
|
N6-Acetyloxymethyladenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N6-Acetyloxymethyladenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
|
-
- HY-154365
-
-
- HY-154521
-
|
2-(4-Methylbenzyl)thioadenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-(4-Methylbenzyl)thioadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
|
-
- HY-154501
-
-
- HY-152460
-
-
- HY-W357137
-
|
L-Threonolactone
(3R,4S)-3,4-Dihydroxyoxolan-2-one
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
L-Threonolactone ((3R,4S)-3,4-Dihydroxyoxolan-2-one) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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-
