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Results for "

annexin

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

10

Peptides

6

MCE Kits

19

Recombinant Proteins

9

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-141644
    PY-60
    4 Publications Verification

    YAP Inflammation/Immunology
    PY-60 is a robust and specific activator of YAP transcriptional activity that targets annexin A2 (ANXA2) with a Kd of 1.4 µM. PY-60 directly binds to ANXA2 and antagonizes its normal cellular function of repressing YAP activity .
    PY-60
  • HY-P1098B
    Ac2-26 ammonium
    3 Publications Verification

    IKK Inflammation/Immunology
    Ac2-26 ammonium is the N-terminal peptide of annexin 1, and has anti-inflammatory activity. Ac2-26 ammonium induces a decrease in IKKβ protein in lysosomes by chaperone-mediated autophagy (CMA). Ac2-26 ammonium ameliorates lung ischemia-reperfusion injury. Ac2-26 ammonium also inhibits airway inflammation and hyperresponsiveness in an asthma rat model .
    Ac2-26 ammonium
  • HY-136466

    Virus Protease HPV Infection
    A2ti-2 is a selective and low-affinity annexin A2/S100A10 heterotetramer (A2t) inhibitor with an IC50 of 230 μM . A2ti-2 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. A2ti-2 prevents human papillomavirus type 16 (HPV16) infection .
    A2ti-2
  • HY-136465
    A2ti-1
    2 Publications Verification

    Virus Protease HPV Infection
    A2ti-1 is a selective and high-affinity annexin A2/S100A10 heterotetramer (A2t) inhibitor with an IC50 of 24 μM . A2ti-1 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. A2ti-1 prevents human papillomavirus type 16 (HPV16) infection .
    A2ti-1
  • HY-P1118

    Formyl Peptide Receptor (FPR) Inflammation/Immunology
    Ac9-25, a N-terminal peptide of Annexin I, acts as a formyl peptide receptor (FPR) agonist and activates the neutrophil NADPH oxidase through FPR .
    Ac9-25
  • HY-P1118A

    Formyl Peptide Receptor (FPR) Inflammation/Immunology
    Ac9-25 TFA, a N-terminal peptide of Annexin I, acts as a formyl peptide receptor (FPR) agonist and activates the neutrophil NADPH oxidase through FPR .
    Ac9-25 TFA
  • HY-P1795
    N-Boc-Phe-Leu-Phe-Leu-Phe
    1 Publications Verification

    Boc-FLFLF

    Formyl Peptide Receptor (FPR) Neurological Disease
    N-Boc-Phe-Leu-Phe-Leu-Phe (Boc-FLFLF) is a formyl peptide receptor 1 (FPR1) antagonist, which increases pain effects and inhibits antinociceptive activity of annexin .
    N-Boc-Phe-Leu-Phe-Leu-Phe
  • HY-P1098
    Ac2-26
    3 Publications Verification

    NF-κB Inflammation/Immunology
    Ac2-26, an active N-terminal peptide of annexin A1 (AnxA1), attenuates ischemia-reperfusion-induced acute lung injury. Ac2-26 also decreases AnxA1 protein expression, inhibits the activation of NF-κB and MAPK pathways in the injured lung tissue .
    Ac2-26
  • HY-P1098A
    Ac2-26 TFA
    3 Publications Verification

    NF-κB Inflammation/Immunology
    Ac2-26 TFA, an active N-terminal peptide of annexin A1 (AnxA1), attenuates ischemia-reperfusion-induced acute lung injury. Ac2-26 also decreases AnxA1 protein expression, inhibits the activation of NF-κB and MAPK pathways in the injured lung tissue .
    Ac2-26 TFA
  • HY-149003

    PARP Apoptosis Cancer
    PARP1-IN-10 (compound 12c) is a no-cytotoxicity and potent PARP1 inhibitor with an IC50 value of 50.62 nM in vitro. PARP1-IN-10 causes cell cycle arrest at G2/M phase and apoptosis, and enhances the cytotoxicity of temozolomide (TMZ) .
    PARP1-IN-10

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