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Results for "

anti-cholinesterase

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

4

Natural
Products

1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-107569
    Garcinol
    1 Publications Verification

    		 Cholinesterase (ChE) Histone Acetyltransferase Apoptosis Endogenous Metabolite Inflammation/Immunology Cancer
    Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 µM and 7.39 µM, respectively . Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity .
    Garcinol
  • HY-122437
    Quinuronium disulfate

    		Bacterial Infection Inflammation/Immunology
    Quinuronium disulfate, a babesicidal agent, possesses anticholinesterase activity .
    Quinuronium disulfate
  • HY-N3894
    Ferulamide

    		nAChR Neurological Disease
    Ferulamide is a Ferulic acid derivative isolated from Portulaca oleracea L. with anticholinesterase activities .
    Ferulamide
  • HY-N5089
    (+)-Balanophonin

    		Cholinesterase (ChE) Neurological Disease Metabolic Disease Inflammation/Immunology
    (+)-Balanophonin is a phenolic compound that could be isolated from Passiflora edulis. (+)-Balanophonin possesses anti-oxidant, anticholinesterase, anti-inflammatory, anticancer, and antineurodegenerative activities .
    (+)-Balanophonin
  • HY-16183
    Echothiopate iodide

    Echothiophate iodide

    		 Cholinesterase (ChE) Neurological Disease
    Echothiopate iodide is a potent hBChE (human butyrylcholinesterase) inhibitor. Echothiopate iodide is a long-acting anticholinesterase agent. Echothiopate iodide can be used for glaucoma research .
    Echothiopate iodide
  • HY-B0841S
    Acephate-d3

    		Isotope-Labeled Compounds Cholinesterase (ChE) Neurological Disease
    Acephate-d3 is the deuterium labeled Acephate. Acephate is an anticholinesterase insecticide that produces cholinotoxicity. Acephate displays weak inhibition of rat AChE but potently inhibits cockroach AChE.
    Acephate-d3
  • HY-B0841
    Acephate

    		Cholinesterase (ChE) Neurological Disease
    Acephate is a broad-spectrum anticholinesterase insecticide. Acephate acts via inhibiting AChE (Cholinesterase (ChE)) activity of insects. Acephate is used for control of several species of insects in agriculture and in horticulture .
    Acephate
  • HY-119577
    Ubretid

    Distigmine dibromide

    		 Cholinesterase (ChE) Neurological Disease
    Ubretid is a potent inhibitor of plasma cholinesterase. Ubretid therefore delays the hydrolysis of suxamethonium and prolongs its action, similar to the effects shown by other anticholinesterase agents, such as pyridostigmine and donepezil. Ubretid has the potential for the research of urinary retention prolongs the effect of suxamethonium. Ubretid is commonly prescribed for the research of myasthenia gravis and for difficulty in emptying the bladder .
    Ubretid
  • HY-17387
    (-)-Huperzine A
    3 Publications Verification

    Huperzine A

    		 Cholinesterase (ChE) Apoptosis iGluR Neurological Disease
    (-)-Huperzine A (Huperzine A) is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC50 of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimer’s disease .
    (-)-Huperzine A
  • HY-Y0320
    Dimethyl sulfoxide
    Maximum Cited Publications
    89 Publications Verification

    DMSO
    Dimethyl sulfoxide (DMSO) is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties .
    MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition).
    Dimethyl sulfoxide

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