Search Result

Results for "

anti-oxidative

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetyl-CoA Carboxylase (1) Adiponectin Receptor (1) Adrenergic Receptor (1) Akt (2) AMPK (3) Amylases (1) Amyloid-β (3) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (4) AP-1 (1) Apoptosis (42) Aurora Kinase (3) Autophagy (14) Bacterial (9) Bcl-2 Family (1) Beta-secretase (1) Biochemical Assay Reagents (1) Calcium Channel (1) Caspase (2) COX (2) Cytochrome P450 (1) DNA Methyltransferase (1) DNA/RNA Synthesis (3) Dopamine Receptor (2) Endogenous Metabolite (24) ERK (3) Ferroptosis (1) Fungal (10) GABA Receptor (1) Glucosidase (2) HCV (2) HDAC (2) HIF/HIF Prolyl-Hydroxylase (1) Histamine Receptor (1) HIV (1) HSP (2) HSV (1) Indoleamine 2,3-Dioxygenase (IDO) (3) Influenza Virus (6) Interleukin Related (3) Isotope-Labeled Compounds (3) JNK (2) Keap1-Nrf2 (11) Melatonin Receptor (4) Mitophagy (5) MMP (3) Monoamine Oxidase (1) mTOR (1) NF-κB (14) NO Synthase (1) Opioid Receptor (1) P2X Receptor (1) p38 MAPK (2) Parasite (7) PD-1/PD-L1 (1) PDGFR (1) PGE synthase (1) Phosphodiesterase (PDE) (2) Phospholipase (1) PINK1/Parkin (1) PPAR (2) Prostaglandin Receptor (1) Proteasome (1) RAR/RXR (1) Reactive Oxygen Species (22) Ribosomal S6 Kinase (RSK) (1) ROS Kinase (1) RSV (1) SARS-CoV (2) SOD (1) STAT (1) TNF Receptor (1) Tyrosinase (2) Vasopressin Receptor (3) Virus Protease (5) Xanthine Oxidase (4)
By Research Areas:	Cancer (67) Cardiovascular Disease (16) Endocrinology (3) Infection (28) Inflammation/Immunology (80) Metabolic Disease (35) Neurological Disease (34)

By Targets:

Acetyl-CoA Carboxylase (1)

Adiponectin Receptor (1)

Adrenergic Receptor (1)

Akt (2)

AMPK (3)

Amylases (1)

Amyloid-β (3)

Angiotensin-converting Enzyme (ACE) (1)

Antibiotic (4)

AP-1 (1)

Apoptosis (42)

Aurora Kinase (3)

Autophagy (14)

Bacterial (9)

Bcl-2 Family (1)

Beta-secretase (1)

Biochemical Assay Reagents (1)

Calcium Channel (1)

Caspase (2)

COX (2)

Cytochrome P450 (1)

DNA Methyltransferase (1)

DNA/RNA Synthesis (3)

Dopamine Receptor (2)

Endogenous Metabolite (24)

ERK (3)

Ferroptosis (1)

Fungal (10)

GABA Receptor (1)

Glucosidase (2)

HCV (2)

HDAC (2)

HIF/HIF Prolyl-Hydroxylase (1)

Histamine Receptor (1)

HIV (1)

HSP (2)

HSV (1)

Indoleamine 2,3-Dioxygenase (IDO) (3)

Influenza Virus (6)

Interleukin Related (3)

Isotope-Labeled Compounds (3)

JNK (2)

Keap1-Nrf2 (11)

Melatonin Receptor (4)

Mitophagy (5)

MMP (3)

Monoamine Oxidase (1)

mTOR (1)

NF-κB (14)

NO Synthase (1)

Opioid Receptor (1)

P2X Receptor (1)

p38 MAPK (2)

Parasite (7)

PD-1/PD-L1 (1)

PDGFR (1)

PGE synthase (1)

Phosphodiesterase (PDE) (2)

Phospholipase (1)

PINK1/Parkin (1)

PPAR (2)

Prostaglandin Receptor (1)

Proteasome (1)

RAR/RXR (1)

Reactive Oxygen Species (22)

Ribosomal S6 Kinase (RSK) (1)

ROS Kinase (1)

RSV (1)

SARS-CoV (2)

SOD (1)

STAT (1)

TNF Receptor (1)

Tyrosinase (2)

Vasopressin Receptor (3)

Virus Protease (5)

Xanthine Oxidase (4)

By Research Areas:

Cancer (67)

Cardiovascular Disease (16)

Endocrinology (3)

Infection (28)

Inflammation/Immunology (80)

Metabolic Disease (35)

Neurological Disease (34)

191

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

137

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Oxidative Phosphorylation

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12840

OBA-09	Reactive Oxygen Species	Neurological Disease
OBA-09, a simple ester of pyruvate and salicylic acid, is potent multi-modal neuroprotectant. OBA-09 has anti-oxidative and anti-inflammatory effects .

HY-N5135

Liriopesides B Nolinospiroside F	Others	Others
Liriopesides B (Nolinospiroside F) is a steroidal saponin isolated from Ophiopogon japonicas. Liriopesides B has anti-oxidative and anti-aging effects .

HY-125938

Cycloartenyl ferulate 1 Publications Verification Cycloartenol ferulate; Cycloartenol ferulic acid ester	Others	Inflammation/Immunology Cancer
Cycloartenyl ferulate (Cycloartenol ferulate) is one of the typical triterpene alcohols and possesses several biological activities including anti-oxidative activity, antiallergic activity, anti-inflammatory and anticancer activities .

HY-N11767

Prenyletin	Others	Others
Prenyletin is a natural product, that can be isolated from the roots of Ptaeroxylon obliquum Radlk. (Rutaceae). Prenyletin shows anti-oxidative stress activity .

HY-N11136

Schizolaenone C	Others	Cancer
Schizolaenone C is a natural product that can be found in Schizolaena hystrix. Schizolaenone C exhibits anti-proliferative and anti-oxidative activities .

HY-150156

Anti-inflammatory agent 32	Others	Inflammation/Immunology
Anti-inflammatory agent 32 (compound C3) has anti-oxidative and anti-inflammatory activity. Anti-inflammatory agent 32 can be used for skin care products research and development .

HY-N0334

(+)-Magnoflorine Magnoflorine; α-Magnoflorine; Thalictrine	Fungal	Infection Metabolic Disease
(+)-Magnoflorine (Magnoflorine), an aporphine alkaloid found in Acoruscalamus, reduces the formation of C. albicans biofilm . (+)-Magnoflorine has anti-fungal, anti-antidiabetic and anti-oxidative activity .

HY-N0535

(+)-Magnoflorine chloride Magnoflorine chloride; α-Magnoflorine chloride; Thalictrine chloride	Fungal	Infection Metabolic Disease
Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Magnolia or Aristolochia, reduces the formation of C. albicans biofilm . Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity .

HY-108966

Kushenol C	Beta-secretase	Inflammation/Immunology
Kushenol C, isolated from the roots of Sophora flavescens, shows anti-Inflammatory and anti-oxidative stress activities. Kushenol C inhibits BACE1 (β-site APP cleaving enzyme 1) with an IC₅₀ of 5.45 µM .

HY-N0334A

(+)-Magnoflorine iodide Magnoflorine iodide; α-Magnoflorine iodide; Thalictrine iodide	Fungal	Infection Metabolic Disease
(+)-Magnoflorine iodide (Magnoflorine iodide), an aporphine alkaloid found in Acoruscalamus, reduces the formation of C. albicans biofilm . (+)-Magnoflorine iodide has anti-fungal, anti-antidiabetic and anti-oxidative activity .

HY-15121

L-Theanine 1 Publications Verification L-Glutamic Acid γ-ethyl amide; Nγ-Ethyl-L-glutamine	Apoptosis Endogenous Metabolite Reactive Oxygen Species	Neurological Disease Cancer
L-Theanine (L-Glutamic Acid γ-ethyl amide) is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective, anticancer and anti-oxidative activities. L-Theanine can pass through the blood–brain barrier and is orally active .

HY-124411

Lobenzarit

Others Inflammation/Immunology

Lobenzarit, an immunomodulator, possesses anti-oxidative .

Lobenzarit	Others	Inflammation/Immunology
Lobenzarit, an immunomodulator, possesses anti-oxidative .

HY-N0452

Hyperoside 4 Publications Verification	Influenza Virus Fungal NF-κB Apoptosis	Infection Inflammation/Immunology Cancer
Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis .

HY-W015635

Diallyl disulfide	Others	Cancer
Diallyl disulfide, an active compound in garlic oil, is an orally active human squalene monooxygenase inhibitor with an IC₅₀ of 400 μM for squalene epoxidation. Diallyl disulfide exhibits obvious anti-inflammatory, anti-oxidative, antidepressant and anti-tumor activities .

HY-107360

Lobenzarit disodium

CCA
Reactive Oxygen Species Inflammation/Immunology

Lobenzarit disodium (CCA) is an anti-arthritic and anti-oxidative agent .

Lobenzarit disodium CCA	Reactive Oxygen Species	Inflammation/Immunology
Lobenzarit disodium (CCA) is an anti-arthritic and anti-oxidative agent .

HY-N0741A

Leonurine hydrochloride 5+ Cited Publications SCM-198 hydrochloride	Autophagy	Inflammation/Immunology Cancer
Leonurine hydrochloride is an alkaloid isolated from Leonurus artemisia, with anti-oxidative and anti-inflammatory.

HY-N0741

Leonurine 5+ Cited Publications SCM-198	Autophagy	Inflammation/Immunology Cancer
Leonurine is an alkaloid isolated from Leonurus artemisia, with anti-oxidative and anti-inflammatory.

HY-N5021

Anhydrosafflor yellow B AHSYB	Others	Neurological Disease
Anhydrosafflor yellow B (AHSYB) is a quinochalcone C-glycoside isolated from Carthamus tinctorius. Anhydrosafflor yellow B inhibits ADP-induced platelet aggregation, exhibits significant anti-oxidative effects in vitro, and possesses certain activity against H₂O₂-induced cytotoxicity in cultured PC12 cells and primary neuronal cells .

HY-126397

MnTBAP chloride 1 Publications Verification	NF-κB	Inflammation/Immunology
MnTBAP chloride is a superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. MnTBAP chloride is a manganic porphyrin complex and has anti-oxidative property. MnTBAP chloride mediates anti-inflammatory effects through upregulation of BMPR-II and inhibition of the NFκB signaling. MnTBAP chloride has the potential for the fibrotic response in chronic kidney diseases (CKDs) research .

HY-N2437

Methylophiopogonanone A 1 Publications Verification	Others	Inflammation/Immunology
Methylophiopogonanone A, a major homoisoflavonoid in Ophiopogon japonicas, has both anti-oxidative and anti-inflammatory properties .

HY-N0327

Lobetyolin	Apoptosis Xanthine Oxidase	Metabolic Disease
Lobetyolin, a bioactive compound, is derived from Codonopsis pilosula. Lobetyolin has anti-inflammatory, anti-oxidative and xanthine oxidase inhibiting activities. Lobetyolin also induces the apoptosis via the inhibition of ASCT2-mediated glutamine metabolism . Lobetyolin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-12554

Terlipressin	Vasopressin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology
Terlipressin is a vasopressin analogue with potent vasoactive properties. Terlipressin is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin exerts anti-inflammatory and anti-oxidative effects. Terlipressin has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .

HY-12554A

Terlipressin diacetate 1 Publications Verification	Vasopressin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology
Terlipressin diacetate is a vasopressin analogue with potent vasoactive properties. Terlipressin diacetate is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin diacetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin diacetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .

HY-12554B

Terlipressin acetate	Vasopressin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology
Terlipressin acetate is a vasopressin analogue with potent vasoactive properties. Terlipressin acetate is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin acetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin acetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .

HY-N0073

Sarsasapogenin 3 Publications Verification Parigenin; Sarsagenin	Endogenous Metabolite NF-κB	Metabolic Disease Inflammation/Immunology Cancer
Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities.

HY-N7937

γ-Asarone	Others	Inflammation/Immunology
γ-Asarone, a phenylpropene, shows strong correlation with the biological activities (anti-oxidative, anti-inflammatory and neurotrophic effects) .

HY-137315

TML-6	Amyloid-β NF-κB mTOR Keap1-Nrf2	Neurological Disease
TML-6, an orally active curcumin derivative, inhibits the synthesis of the β-amyloid precursor protein and β-amyloid (Aβ). TML-6 can upregulate Apo E, suppress NF-κB and mTOR, and increase the activity of the anti-oxidative Nrf2 gene. TML-6 has the potential for Alzheimer’s disease (AD) research .

HY-W011704A

Phosphoenolpyruvic acid tricyclohexylammonium salt	Endogenous Metabolite	Others
Phosphoenolpyruvic acid tricyclohexylammonium salt is a glycolysis metabolite with a high-energy phosphate group, penetrates the cell membrane and exhibits cytoprotective and anti-oxidative activity .

HY-N7617

Toralactone

Keap1-Nrf2 Cancer

Toralactone, isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism .

Toralactone	Keap1-Nrf2	Cancer
Toralactone, isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism .

HY-N0293

Paeoniflorin 15+ Cited Publications Peoniflorin	HSP	Infection Neurological Disease Cancer
Paeoniflorin is a heat shock protein-inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity .

HY-N7078

Spiculisporic acid	Biochemical Assay Reagents	Others
Spiculisporic acid is a γ-butenolide isolated from the cultue of Aspergillus sp . Spiculisporic acid is a microbial biosurfactant and has anti-oxidative stress actions .

HY-N0579

Fraxin 2 Publications Verification Fraxoside	Phosphodiesterase (PDE)	Inflammation/Immunology
Fraxin isolated from Cortex Fraxini, is a glucoside of fraxetin and reported to exert potent anti-oxidative stress action , anti-inflammatory and antimetastatic properties. Fraxin shows its antioxidative effect through inhibition of cyclo AMP phosphodiesterase enzyme .

HY-N0783

Eupatilin 5+ Cited Publications	PPAR Autophagy	Neurological Disease Inflammation/Immunology Cancer
Eupatilin, a lipophilic flavonoid isolated from Artemisia argyi Lévl. et Van., is a PPARα* agonist, and possesses anti-apoptotic, anti-oxidative and anti-inflammatory activities.*

HY-N0474

Tyrosol 1 Publications Verification	NF-κB Endogenous Metabolite	Inflammation/Immunology
Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects .

HY-125847

Salvianolic acid F	Others	Cancer
Salvianolic acid F is a kind of Salvianolic Acids. Salvianolic Acids is the most effective and abundant compounds extracted from Salvia miltiorrhiza, with good anti-oxidative activity .

HY-N0344

Farrerol 1 Publications Verification	Others	Neurological Disease Inflammation/Immunology Cancer
Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects .

HY-N1181

Tamarixetin 4'-O-Methyl Quercetin
Tamarixetin (4'-O-Methyl Quercetin) is a natural flavonoid derivative of quercetin, with anti-oxidative and anti-inflammatory effects. Tamarixetin protects against cardiac hypertrophy .

HY-N0765

Isoliquiritin 1 Publications Verification	Fungal	Infection Neurological Disease Inflammation/Immunology
Isoliquiritin, isolated from Licorice Root, inhibits angiogenesis and tube formation. Isoliquiritin also exhibits antidepressant-like, anti-oxidative, anti-Inflammatory effects and antifungal activity .

HY-B1135

Benzbromarone 3 Publications Verification	Xanthine Oxidase Apoptosis Interleukin Related Keap1-Nrf2 SOD Caspase Bcl-2 Family NF-κB JNK HSP	Metabolic Disease
Benzbromarone is an orally active anti-gout agent. Benzbromarone has anti-infammatory, anti-oxidative stress and nephroprotective effects. Benzbromarone can be used for the research of hyperuricemia and gout .

HY-N0164

Matrine 10+ Cited Publications Matridin-15-one; Vegard; α-Matrine	PINK1/Parkin Opioid Receptor Autophagy Mitophagy Ferroptosis Apoptosis	Inflammation/Immunology Cancer
Matrine (Matridin-15-one) is an alkaloid found in plants from the Sophora genus that can act as a kappa opioid receptor and u-receptor agonist. Matrine has a variety of pharmacological effects, including anti-cancer, anti-oxidative stress, anti-inflammation and anti-apoptosis effects. Matrine is potential in the research of disease like human non-small cell lung cancer, hepatoma, papillary thyroid cancer and acute kidney injury (AKI) .

HY-B2230

Hinokitiol 5 Publications Verification β-Thujaplicin	Keap1-Nrf2 DNA Methyltransferase Virus Protease	Infection Cancer
Hinokitiol is a component of essential oils isolated from Chymacyparis obtusa, reduces Nrf2 expression, and decreases DNMT1 and UHRF1 mRNA and protein expression, with anti-infective, anti-oxidative, and anti-tumor activities.

HY-N0823

Lithospermic acid (+)-Lithospermic acid	Others	Inflammation/Immunology
Lithospermic acid ((+)-Lithospermic acid) is a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, and has the anti-oxidative and hepatoprotective activity on carbon tetrachloride (CCl₄)-induced acute liver damage in vitro and in vivo .

HY-W166297

Esculin sesquihydrate	p38 MAPK	Cancer
Esculin sesquihydrate, a fluorescent coumarin glucoside, is an active ingredient of ash bark. Esculin sesquihydrate ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti?oxidative stress and anti?inflammatory effects, via the MAPK signaling pathway .

HY-N0783R

Eupatilin (Standard)	PPAR Autophagy	Neurological Disease Inflammation/Immunology Cancer
Eupatilin (Standard) is the analytical standard of Eupatilin. This product is intended for research and analytical applications. Eupatilin, a lipophilic flavonoid isolated from Artemisia argyi Lévl. et Van., is a PPARα* agonist, and possesses anti-apoptotic, anti-oxidative and anti-inflammatory activities.*

HY-145532

S-Allylmercaptocysteine	Apoptosis NF-κB Keap1-Nrf2	Inflammation/Immunology Cancer
S-allylmercaptocysteine, an organic sulfur compound extracted from garlic, has anti-inflammatory and anti-oxidative effects for various pulmonary diseases. S-allylmercaptocysteine achieves its anti-cancer effect through a variety of pathways such as inducing the apoptosis of cancer cells through the TGF-β signaling pathway, or reducing the NF-κB activity and up-regulating Nrf2 to achieve the effects of anti-inflammation and anti-oxidation .

HY-N0526

2"-O-Galloylhyperin	Others	Inflammation/Immunology
2"-O-Galloylhyperin, an active compound isolated from Pyrola incarnate Fisch., possesses anti-oxidative and anti-inflammatory activities. 2"-O-Galloylhyperin has hepatoprotective effect against oxidative stress-induced liver damage .

HY-N9975

4'',5''-Dehydroisopsoralidin	Others	Inflammation/Immunology Cancer
4'',5''-Dehydroisopsoralidin is a β-glucuronidase inhibitor (IC₅₀: 6.3 μM). 4'',5''-Dehydroisopsoralidin has anti-inflammatory and anti-oxidative effects. 4'',5''-Dehydroisopsoralidin can be used in the research of inflammation and cancners .

HY-100768

HTHQ 2 Publications Verification 1-O-hexyl-2,3,5-trimethylhydroquinone; HX-1171; BTT-105	Reactive Oxygen Species	Cancer
HTHQ (1-O-hexyl-2,3,5-trimethylhydroquinone) is a potent lipophilic phenolic antioxidant. HTHQ has considerable anti-oxidative activity by directly reacting with reactive oxygen species (ROS) and scavenging ROS to form more stable free radicals .

HY-N0120

(E/Z)-Polydatin (E/Z)-Piceid	Others	Inflammation/Immunology
(E/Z)-Polydatin ((E/Z)-Piceid) is a monocrystalline compound originally isolated from the root and rhizome of Polygonum cuspidatum. (E/Z)-Polydatin has anti-platelet aggregation, anti-oxidative action of low-density lipoprotein (LDL), cardioprotective activity, anti-inflammatory and immune-regulating functions .

HY-N2204

Swertiajaponin
Swertiajaponin is a tyrosinase inhibitor, forms multiple hydrogen bonds and hydrophobic interactions with the binding pocket of tyrosinase, with an IC₅₀ of 43.47 μM. Swertiajaponin also inhibits oxidative stress-mediated MAPK/MITF signaling, leading to decrease in tyrosinase protein level. Swertiajaponin suppresses melanin accumulation and exhibits strong anti-oxidative activity .

Cat. No.	Product Name

HY-L042

Glycoside Compound Library

789 compounds

Glycosides are compounds in which a sugar group is bonded through its anomeric carbon to another group via a glycosidic bond. Many biologically active compounds are glycosides. Glycosides comprise several important classes of compounds such as hormones, sweeteners, alkaloids, flavonoids, antibiotics, etc. The glycosidic residue can be crucial for their activity or can only improve pharmacokinetic parameters. Glycosides, which exhibit anti-inflammatory, anti-infection, anti-cancer and anti-oxidative properties, play numerous important roles in living organisms, such as streptomycin, as an aminoglycoside antibiotic, has anti-infection activity. Anthracyclines possess good antibacterial and anti-cancer activities.

MCE Glycoside Compound Library contains a unique collection of 789 glycoside compounds and is a useful tool to discovery glycoside drugs.

HY-L068

Flavonoids Library

512 compounds

Flavonoids are an important class of natural products; particularly, they belong to a class of plant secondary metabolites having a polyphenolic structure, widely found in fruits, vegetables and certain beverages. Flavonoids can be subdivided into different subgroups depending on the carbon of the C ring on which the B ring is attached and the degree of unsaturation and oxidation of the C ring. These subgroups are: flavones, flavonols, flavanones, flavanonols, flavanols or catechins, anthocyanins and chalcones. Flavonoids are now considered as an indispensable component in a variety of nutraceutical, pharmaceutical, medicinal and cosmetic applications. This is attributed to their anti-oxidative, anti-inflammatory, anti-mutagenic and anti-carcinogenic properties coupled with their capacity to modulate key cellular enzyme function. Naturally occurring flavonoids are known to have biological activities for use as drugs, for example, in diseases like cancer, Alzheimer’s disease (AD), atherosclerosis, etc.

MCE offers a unique collection of 512 natural flavonoid compounds which is a useful tool for drug discovery as an important source of lead compounds.

Cat. No.	Product Name	Target	Research Area

HY-12554A

Terlipressin diacetate 1 Publications Verification	Vasopressin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology
Terlipressin diacetate is a vasopressin analogue with potent vasoactive properties. Terlipressin diacetate is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin diacetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin diacetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .

HY-134124

Glutathione ethyl ester	Reactive Oxygen Species	Inflammation/Immunology
Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .

HY-12554B

Terlipressin acetate	Vasopressin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology
Terlipressin acetate is a vasopressin analogue with potent vasoactive properties. Terlipressin acetate is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin acetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin acetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .

HY-P1032S1

Angiotensin I-13C5,15N (human, mouse, rat)	Isotope-Labeled Compounds Endogenous Metabolite	Others
Angiotensin I- ¹³C₅, ¹⁵N (human, mouse, rat) is the ¹³C and ¹⁵N labeled Angiotensin I (human, mouse, rat) (HY-P1032). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N5135

Liriopesides B Nolinospiroside F	Liliaceae Classification of Application Fields Anti-aging Source classification Other Diseases Liriope spicata (Thunb.) Lour. Plants Disease Research Fields Steroids	Others
Liriopesides B (Nolinospiroside F) is a steroidal saponin isolated from Ophiopogon japonicas. Liriopesides B has anti-oxidative and anti-aging effects .

HY-125938

Cycloartenyl ferulate 1 Publications Verification Cycloartenol ferulate; Cycloartenol ferulic acid ester	Triterpenes Monophenols other families Classification of Application Fields Terpenoids Source classification Phenols Plants Disease Research Fields Inflammation/Immunology	Others
Cycloartenyl ferulate (Cycloartenol ferulate) is one of the typical triterpene alcohols and possesses several biological activities including anti-oxidative activity, antiallergic activity, anti-inflammatory and anticancer activities .

HY-N11767

Prenyletin	Structural Classification Source classification Rutaceae Coumarins Ptaeroxylon obliquum (Thunb.) Radlk. Phenylpropanoids Plants	Others
Prenyletin is a natural product, that can be isolated from the roots of Ptaeroxylon obliquum Radlk. (Rutaceae). Prenyletin shows anti-oxidative stress activity .

HY-N11136

Schizolaenone C	Structural Classification Flavonoids Paulownia tomentosa (Thunb.) Steud. Flavonones Source classification Phenols Polyphenols Scrophulariaceae Plants	Others
Schizolaenone C is a natural product that can be found in Schizolaena hystrix. Schizolaenone C exhibits anti-proliferative and anti-oxidative activities .

HY-N0334

(+)-Magnoflorine Magnoflorine; α-Magnoflorine; Thalictrine	Alkaloids Classification of Application Fields Source classification Ranunculaceae Coptis chinensis Franch. Phenols Polyphenols Metabolic Disease Plants Isoquinoline Alkaloids Disease Research Fields	Fungal
(+)-Magnoflorine (Magnoflorine), an aporphine alkaloid found in Acoruscalamus, reduces the formation of C. albicans biofilm . (+)-Magnoflorine has anti-fungal, anti-antidiabetic and anti-oxidative activity .

HY-N0535

(+)-Magnoflorine chloride Magnoflorine chloride; α-Magnoflorine chloride; Thalictrine chloride	Classification of Application Fields Source classification Metabolic Disease Plants Aristolochiaceae Infection Alkaloids Piperidine Alkaloids other families Aristolochia debilis Sieb. et Zucc. Phenols Polyphenols Disease Research Fields	Fungal
Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Magnolia or Aristolochia, reduces the formation of C. albicans biofilm . Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity .

HY-108966

Kushenol C	Flavonols Flavonoids Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields Inflammation/Immunology	Beta-secretase
Kushenol C, isolated from the roots of Sophora flavescens, shows anti-Inflammatory and anti-oxidative stress activities. Kushenol C inhibits BACE1 (β-site APP cleaving enzyme 1) with an IC₅₀ of 5.45 µM .

HY-N0334A

(+)-Magnoflorine iodide Magnoflorine iodide; α-Magnoflorine iodide; Thalictrine iodide	Alkaloids Classification of Application Fields Source classification Magnoliaceae Phenols Polyphenols Metabolic Disease Magnolia Liliflora Desr. Plants Isoquinoline Alkaloids Disease Research Fields	Fungal
(+)-Magnoflorine iodide (Magnoflorine iodide), an aporphine alkaloid found in Acoruscalamus, reduces the formation of C. albicans biofilm . (+)-Magnoflorine iodide has anti-fungal, anti-antidiabetic and anti-oxidative activity .

HY-15121

L-Theanine 1 Publications Verification L-Glutamic Acid γ-ethyl amide; Nγ-Ethyl-L-glutamine	Structural Classification Microorganisms Neurological Disease Classification of Application Fields Anti-aging Source classification Amino acids Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Theaceae	Apoptosis Endogenous Metabolite Reactive Oxygen Species
L-Theanine (L-Glutamic Acid γ-ethyl amide) is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective, anticancer and anti-oxidative activities. L-Theanine can pass through the blood–brain barrier and is orally active .

HY-N0452

Hyperoside 4 Publications Verification	Flavonols Structural Classification Flavonoids Classification of Application Fields Source classification Guttiferae Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Hypericum monogynum L.	Influenza Virus Fungal NF-κB Apoptosis
Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis .

HY-W015635

Diallyl disulfide	Structural Classification Natural Products Liliaceae Classification of Application Fields Source classification Plants Disease Research Fields A．Sativam L. var．Viviparum Regel Cancer	Others
Diallyl disulfide, an active compound in garlic oil, is an orally active human squalene monooxygenase inhibitor with an IC₅₀ of 400 μM for squalene epoxidation. Diallyl disulfide exhibits obvious anti-inflammatory, anti-oxidative, antidepressant and anti-tumor activities .

HY-N0741A

Leonurine hydrochloride 5+ Cited Publications SCM-198 hydrochloride	Alkaloids Structural Classification Monophenols Classification of Application Fields Other Alkaloids Labiatae Source classification Phenols Lactuca perennis Plants Disease Research Fields Cancer	Autophagy
Leonurine hydrochloride is an alkaloid isolated from Leonurus artemisia, with anti-oxidative and anti-inflammatory.

HY-N0741

Leonurine 5+ Cited Publications SCM-198	Alkaloids Structural Classification Monophenols Classification of Application Fields Labiatae Source classification Phenols Lactuca perennis Plants Disease Research Fields Cancer	Autophagy
Leonurine is an alkaloid isolated from Leonurus artemisia, with anti-oxidative and anti-inflammatory.

HY-N5021

Anhydrosafflor yellow B AHSYB	Quinones Simple Phenylpropanols Carthamus tinctorius L. Source classification Phenols Polyphenols Benzene Quinones Phenylpropanoids Plants Compositae	Others
Anhydrosafflor yellow B (AHSYB) is a quinochalcone C-glycoside isolated from Carthamus tinctorius. Anhydrosafflor yellow B inhibits ADP-induced platelet aggregation, exhibits significant anti-oxidative effects in vitro, and possesses certain activity against H₂O₂-induced cytotoxicity in cultured PC12 cells and primary neuronal cells .

HY-N2437

Methylophiopogonanone A 1 Publications Verification	Ophiopogon japonicus (L. f.) Ker-Gawl. Flavonoids Liliaceae Classification of Application Fields Source classification Phenols Polyphenols Plants Other Flavonoids Disease Research Fields Inflammation/Immunology	Others
Methylophiopogonanone A, a major homoisoflavonoid in Ophiopogon japonicas, has both anti-oxidative and anti-inflammatory properties .

HY-N0327

Lobetyolin	Structural Classification Natural Products Classification of Application Fields Source classification Campanulaceae Metabolic Disease Plants Codonopsis pilosula Disease Research Fields	Apoptosis Xanthine Oxidase
Lobetyolin, a bioactive compound, is derived from Codonopsis pilosula. Lobetyolin has anti-inflammatory, anti-oxidative and xanthine oxidase inhibiting activities. Lobetyolin also induces the apoptosis via the inhibition of ASCT2-mediated glutamine metabolism . Lobetyolin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N0073

Sarsasapogenin 3 Publications Verification Parigenin; Sarsagenin	Liliaceae Classification of Application Fields Source classification Metabolic Disease Anemarrhena asphodeloides Bunge Plants Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Endogenous Metabolite NF-κB
Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities.

HY-N7937

γ-Asarone	Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Inflammation/Immunology Disease Research Fields	Others
γ-Asarone, a phenylpropene, shows strong correlation with the biological activities (anti-oxidative, anti-inflammatory and neurotrophic effects) .

HY-W011704A

Phosphoenolpyruvic acid tricyclohexylammonium salt	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Phosphoenolpyruvic acid tricyclohexylammonium salt is a glycolysis metabolite with a high-energy phosphate group, penetrates the cell membrane and exhibits cytoprotective and anti-oxidative activity .

HY-N7617

Toralactone	Microorganisms Classification of Application Fields Cassia obtusifolia L. Source classification Phenols Polyphenols Caesalpiniaceae Plants Disease Research Fields Cancer	Keap1-Nrf2
Toralactone, isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism .

HY-N0293

Paeoniflorin 15+ Cited Publications Peoniflorin	Structural Classification Other Monoterpenes Paeonia lactiflora Pall. Terpenoids Source classification Plants Paeoniaceae	HSP
Paeoniflorin is a heat shock protein-inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity .

HY-N7078

Spiculisporic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Marine natural products Other Diseases Disease Research Fields Marine microorganism	Biochemical Assay Reagents
Spiculisporic acid is a γ-butenolide isolated from the cultue of Aspergillus sp . Spiculisporic acid is a microbial biosurfactant and has anti-oxidative stress actions .

HY-N0579

Fraxin 2 Publications Verification Fraxoside	Monophenols other families Classification of Application Fields Oleaceae Source classification Fraxinus rhynchophylla Hance Coumarins Phenols Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	Phosphodiesterase (PDE)
Fraxin isolated from Cortex Fraxini, is a glucoside of fraxetin and reported to exert potent anti-oxidative stress action , anti-inflammatory and antimetastatic properties. Fraxin shows its antioxidative effect through inhibition of cyclo AMP phosphodiesterase enzyme .

HY-N0783

Eupatilin 5+ Cited Publications	Structural Classification Flavonoids Neurological Disease Classification of Application Fields Flavones Plants Compositae Disease Research Fields Sindora sumatrana Miq. Cancer	PPAR Autophagy
Eupatilin, a lipophilic flavonoid isolated from Artemisia argyi Lévl. et Van., is a PPARα* agonist, and possesses anti-apoptotic, anti-oxidative and anti-inflammatory activities.*

HY-N0474

Tyrosol 1 Publications Verification	Structural Classification Classification of Application Fields Anti-aging Source classification Plants Burseraceae Endogenous metabolite Monophenols Microorganisms Canarium album (Lour.) Rauesch. Phenols Inflammation/Immunology Disease Research Fields	NF-κB Endogenous Metabolite
Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects .

HY-125847

Salvianolic acid F	Structural Classification Stilbenes Classification of Application Fields Labiatae Source classification Samanea saman (Jacq.) Merr. Phenols Polyphenols Plants Disease Research Fields Cancer	Others
Salvianolic acid F is a kind of Salvianolic Acids. Salvianolic Acids is the most effective and abundant compounds extracted from Salvia miltiorrhiza, with good anti-oxidative activity .

HY-N0344

Farrerol 1 Publications Verification	Flavonoids Classification of Application Fields Neurological Disease Rhododendron dauricum Linn. Flavonones Source classification Phenols Polyphenols Plants Ericaceae Disease Research Fields Inflammation/Immunology	Others
Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects .

HY-N0765

Isoliquiritin 1 Publications Verification	Structural Classification Neurological Disease Classification of Application Fields Source classification Plants Chalcones Flavonoids Leguminosae Phenols Polyphenols Inflammation/Immunology Disease Research Fields Glycyrrhiza uralensis Fisch.	Fungal
Isoliquiritin, isolated from Licorice Root, inhibits angiogenesis and tube formation. Isoliquiritin also exhibits antidepressant-like, anti-oxidative, anti-Inflammatory effects and antifungal activity .

HY-N0164

Matrine 10+ Cited Publications Matridin-15-one; Vegard; α-Matrine	Structural Classification Classification of Application Fields Source classification Sophora flavescens Aiton Plants Biological Pesticide Research Agricultural Research Alkaloids Piperidine Alkaloids Leguminosae Inflammation/Immunology Disease Research Fields Cancer	PINK1/Parkin Opioid Receptor Autophagy Mitophagy Ferroptosis Apoptosis
Matrine (Matridin-15-one) is an alkaloid found in plants from the Sophora genus that can act as a kappa opioid receptor and u-receptor agonist. Matrine has a variety of pharmacological effects, including anti-cancer, anti-oxidative stress, anti-inflammation and anti-apoptosis effects. Matrine is potential in the research of disease like human non-small cell lung cancer, hepatoma, papillary thyroid cancer and acute kidney injury (AKI) .

HY-B2230

Hinokitiol 5 Publications Verification β-Thujaplicin	Infection Cupressaceae Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields Chamaecyparis obtusa	Keap1-Nrf2 DNA Methyltransferase Virus Protease
Hinokitiol is a component of essential oils isolated from Chymacyparis obtusa, reduces Nrf2 expression, and decreases DNMT1 and UHRF1 mRNA and protein expression, with anti-infective, anti-oxidative, and anti-tumor activities.

HY-N0823

Lithospermic acid (+)-Lithospermic acid	Classification of Application Fields Labiatae Source classification Samanea saman (Jacq.) Merr. Other Phenylpropanoids Phenols Polyphenols Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	Others
Lithospermic acid ((+)-Lithospermic acid) is a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, and has the anti-oxidative and hepatoprotective activity on carbon tetrachloride (CCl₄)-induced acute liver damage in vitro and in vivo .

HY-N0783R

Eupatilin (Standard)	Structural Classification Flavonoids Neurological Disease Classification of Application Fields Source classification Plants Compositae Disease Research Fields Sindora sumatrana Miq. Cancer	PPAR Autophagy
Eupatilin (Standard) is the analytical standard of Eupatilin. This product is intended for research and analytical applications. Eupatilin, a lipophilic flavonoid isolated from Artemisia argyi Lévl. et Van., is a PPARα* agonist, and possesses anti-apoptotic, anti-oxidative and anti-inflammatory activities.*

HY-N0526

2"-O-Galloylhyperin	Flavonols Flavonoids Classification of Application Fields Pyrola calliantha H. Andr. Source classification Pyrolaceae Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Pyrola incarnata Fisch. ex DC.	Others
2"-O-Galloylhyperin, an active compound isolated from Pyrola incarnate Fisch., possesses anti-oxidative and anti-inflammatory activities. 2"-O-Galloylhyperin has hepatoprotective effect against oxidative stress-induced liver damage .

HY-N9975

4'',5''-Dehydroisopsoralidin	Structural Classification Classification of Application Fields Solanum lyratum Thunberg Coumarins Phenylpropanoids Plants Solanaceae Inflammation/Immunology Disease Research Fields Cancer	Others
4'',5''-Dehydroisopsoralidin is a β-glucuronidase inhibitor (IC₅₀: 6.3 μM). 4'',5''-Dehydroisopsoralidin has anti-inflammatory and anti-oxidative effects. 4'',5''-Dehydroisopsoralidin can be used in the research of inflammation and cancners .

HY-N0120

(E/Z)-Polydatin (E/Z)-Piceid	Stilbenes Classification of Application Fields Polygonaceae Source classification Reynoutria japonica Houtt. Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology	Others
(E/Z)-Polydatin ((E/Z)-Piceid) is a monocrystalline compound originally isolated from the root and rhizome of Polygonum cuspidatum. (E/Z)-Polydatin has anti-platelet aggregation, anti-oxidative action of low-density lipoprotein (LDL), cardioprotective activity, anti-inflammatory and immune-regulating functions .

HY-N0502

Mogroside V	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Cucurbitaceae Metabolic Disease Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Disease Research Fields Sweeteners Food Research	Reactive Oxygen Species
Mogroside V is a the major active constituent of a traditional Chinese medicine Siraitiae Fructus. Mogroside V reduces the intracellular reactive oxygen species (ROS) levels and enhances mitochondrial function. Mogroside V has anti-oxidative, anti-diabetic and anti-carcinogenic effects. Mogroside V can be used for diabetic diseases research .

HY-N6959

Osmundacetone	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Labiatae Source classification Phenols Polyphenols Metabolic Disease Helianthella quinquenervis (Hook.) A.Gray Plants Disease Research Fields	Reactive Oxygen Species Apoptosis
Osmundacetone is a natural product isolated from Osmundae Rhizoma, with neuroprotective and anti-apoptotic effects. Osmundacetone also has DPPH scavenging activity and anti-oxidative stress activity. Osmundacetone inhibits MAPK phosphorylation, including JNK, ERK, and p38 kinase. Osmundacetone can be a potential agent for the research of neurodegenerative diseases .

HY-N2082

Isorhamnetin 3-O-galactoside 1 Publications Verification Cacticin	Cardiovascular Disease Flavonols Flavonoids Classification of Application Fields Typhaceae Source classification Typha angustifolia L. Phenols Polyphenols Plants Disease Research Fields	Others
Isorhamnetin 3-O-galactoside (Cacticin), a flavonoid glycoside isolated from Artemisia capillaris Thunberg, which ameliorates CCl4-induced hepatic damage by enhancing the anti-oxidative defense system and reducing the inflammatory signaling pathways. Isorhamnetin 3-O-galactoside (Cacticin) has antithrombotic and anti-inflammatory activities .

HY-N0460

1-Caffeoylquinic acid	Phyllodium pulchellum (L.) Desv. Classification of Application Fields Source classification Phenols Polyphenols Plants Compositae Disease Research Fields Cancer	NF-κB
1-Caffeoylquinic acid is an effective NF-κB inhibitor, shows significant binding affinity to the RH domain of p105 with K_i of 0.002 μM and binding energy of 1.50 Kcal/mol . 1-Caffeoylquinic acid has anti-oxidative stress ability . 1-Caffeoylquinic acid inhibits PD-1/PD-L1 interact .

HY-N0405

Orientin 2 Publications Verification	Structural Classification Flavonoids other families Flavones Source classification Phenols Polyphenols Plants	TNF Receptor Interleukin Related
Orientin is a neuroprotective agentinhibits which has anti-inflammation, anti-oxidative, anti-tumor, and cardio protection properties. Orientin inhibits the levels of IL-6, IL-1β and TNF-α. Orientin increases IL-10 level. Orientin exhibits neuroprotective effect by inhibits TLR4 and NF-kappa B signaling pathway. Orientin can used in study neuropathic pain .

HY-N0540

Cynaroside 5+ Cited Publications Luteolin 7-glucoside; Luteolin 7-O-β-D-glucoside	Infection Structural Classification Flavonoids Classification of Application Fields Flavones Centaurea ornata Phenols Polyphenols Umbelliferae Plants Disease Research Fields	Influenza Virus DNA/RNA Synthesis Apoptosis Parasite Bacterial Fungal
Cynaroside (Luteolin 7-glucoside) is a flavonoid compound that exhibits anti-oxidative capabilities. Cynaroside is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC₅₀ of 32 nM. Cynaroside also is a promising inhibitor for H₂O₂-induced apoptosis, has cytoprotection against oxidative stress-induced cardiovascular diseases. Cynaroside also has antibacterial, antifungal and anticancer activities, antioxidant and anti-inflammatory activities .

HY-N2447

Amarogentin 2 Publications Verification	Structural Classification Gentiana scabra Bunge Iridoids Classification of Application Fields Terpenoids Source classification Gentianaceae Phenols Polyphenols Metabolic Disease Plants Disease Research Fields	AMPK Apoptosis
Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .

HY-N9182

Zeaxanthin dipalmitate Physalien	Classification of Application Fields Terpenoids Source classification Diterpenoids Plants Solanaceae Lycium chinense Miller Disease Research Fields Inflammation/Immunology	Adiponectin Receptor P2X Receptor Autophagy
Zeaxanthin dipalmitate (Physalien) is a wolfberry-derived carotenoid, has anti-inflammatory and anti-oxidative stress effects. Zeaxanthin dipalmitate directly interact with p2X7 receptor (K_d=81.2 nM) and adiponectin receptor 1 (AdipoR1; K_d=533 nM) in a positive dose-dependent manner. Zeaxanthin dipalmitate restores mitochondrial autophagy functions suppressed by ethanol intoxication. Zeaxanthin dipalmitate can be used in the research of alcoholic fatty liver disease (AFLD) and retinitis pigmentosa (RP) .

HY-N4226

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid	other families Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields Cancer	AP-1
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid is from Cordyceps bassiana, which is one of Cordyceps species with anti-oxidative, anti-cancer, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic, and anti-nociceptive activities. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid targets to block AP-1-mediated luciferase activity, implying it has an anti-inflammatory function .

HY-N0540R

Cynaroside (Standard) Luteolin 7-glucoside (Standard); Luteolin 7-O-β-D-glucoside (Standard)	Structural Classification Flavonoids Phenols	Apoptosis DNA/RNA Synthesis Parasite Bacterial Influenza Virus Fungal
Cynaroside (Standard) is the analytical standard of Cynaroside. This product is intended for research and analytical applications. Cynaroside (Luteolin 7-glucoside) is a flavonoid compound that exhibits anti-oxidative capabilities. Cynaroside is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC₅₀ of 32 nM. Cynaroside also is a promising inhibitor for H₂O₂-induced apoptosis, has cytoprotection against oxidative stress-induced cardiovascular diseases. Cynaroside also has antibacterial, antifungal and anticancer activities, antioxidant and anti-inflammatory activities .

HY-N0403

2,3,4',5-Tetrahydroxystilbene 2-O-β-D-glucoside	Structural Classification Polygonaceae Reynoutria japonica Houtt. Source classification Phenols Polyphenols Plants	Apoptosis
2,3,4',5-Tetrahydroxystilbene 2-O-β-D-glucoside (TSG) is an active product that can be extracted from Polygonum multiflorum Thunb. TSG has anti-inflammatory, antioxidative, anti-atherosclerotic, *anti-apoptotic*, and free radical scavenging activities, TSG is also indicated to facilitate long-term potentiation and learning and memory in both normal and pathological conditions .

HY-N10284

Tetrahydroauroglaucin	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Polyphenols Disease Research Fields	Others
Tetrahydroauroglaucin is a member of hydroquinones, with antioxidative effects .

HY-N10276

Morelloflavone	Structural Classification Flavonoids other families Classification of Application Fields Source classification Phenols Polyphenols Plants Biflavones Inflammation/Immunology Disease Research Fields	Antibiotic
Morelloflavone has antioxidative, antiviral, and anti-inflammatory properties.

HY-N6582

Flavokawin C	Structural Classification Chalcones Flavonoids Humulus lupulus L. Source classification Plants Moraceae	Others
Flavokawin C is a natural compound with antioxidative and cytotoxicity .

HY-N6922

Danshenxinkun B	Quinones Classification of Application Fields Labiatae Source classification Samanea saman (Jacq.) Merr. Metabolic Disease Plants Phenanthrenequinones Disease Research Fields	Others
Danshenxinkun B is an antioxidative component of tanshen (Salvia miltiorhiza Bung) .

Cat. No.	Product Name	Chemical Structure

HY-15121S

L-Theanine-d5

L-Theanine-d₅ is the deuterium labeled L-Theanine. L-Theanine (L-Glutamic Acid γ-ethyl amide）is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective and anti-oxidative activities. L-Theanine causes anti-stress effects via the inhibition of cortical neuron excitation by oral intake[1][2][3].

HY-N1902S

4-Hydroxyphenylacetic acid-d6
4-Hydroxyphenylacetic acid-d₆ is the deuterium labeled 4-Hydroxyphenylacetic acid. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2[1].

HY-W012788S

Maltol-d3
Maltol-d₃ is a deuterium labeled Maltol (HY-W012788). Maltol, a type of aromatic compound, exists in high concentrations in red ginseng. Maltol is a potent antioxidative agent and typically is used to enhance flavor and preserve food .

HY-B0075S

Melatonin-d4
Melatonin-d₄ is deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Antioxidative and anti-inflammatory properties[1][2][3]. Melatonin is a selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation[4].

HY-N1902S1

4-Hydroxyphenylacetic acid-d4
4-Hydroxyphenylacetic acid-d₄ is the deuterium labeled 4-Hydroxyphenylacetic acid[1]. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2[2].

HY-N1428S3

Citric acid-13C3
Citric acid- ¹³C₃ is the ¹³C labeled Citric acid[1]. Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice[2][3][4].

HY-N0273S

Brassinolide-d5

Brassinolide-d₅ (Brassin lactone-d₅) is the deuterated labeled Brassinolide (HY-N0273). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice .

HY-P1032S1

Angiotensin I-13C5,15N (human, mouse, rat)

Angiotensin I- ¹³C₅, ¹⁵N (human, mouse, rat) is the ¹³C and ¹⁵N labeled Angiotensin I (human, mouse, rat) (HY-P1032). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice .

HY-B0075S2

Melatonin-d7

Melatonin-d₇ is the deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties[1][2][3]. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation[4]. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress[5].

HY-B0075S1

Melatonin-d3

Melatonin-d₃ is the deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties[1][2][3]. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation[4]. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress[5].

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