Search Result
Results for "
antibiotic
" in MedChemExpress (MCE) Product Catalog:
2550
Inhibitors & Agonists
11
Biochemical Assay Reagents
183
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-B1915
-
|
Gentamicin C2b; antibiotic XK-62-2; Sagamicin
|
Antibiotic
Bacterial
|
Infection
|
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Micronomicin (Gentamicin C2b) is an aminoglycoside antibiotic, with antibacterial and bactericidal activities .
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-
-
- HY-100833
-
-
-
- HY-137085
-
|
|
Antibiotic
Fungal
|
Infection
|
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Antibiotic AB023b is part of macrocyclic pentaene antibiotic complex, forming the main components with Antibiotic AB023a (HY-137084). Antibiotic AB023b exhibits antifungal activity against Candida albicans, and plant pathogenic fungi, Botrytis cinerea, Fusarium moniliforme and Pythium ultimum .
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-
-
- HY-137084
-
|
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Antibiotic
Fungal
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Infection
|
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Antibiotic AB023a is part of macrocyclic pentaene antibiotic complex, forming the main components with Antibiotic AB023b (HY-137085). Antibiotic AB023a exhibits antifungal activity against Candida albicans, and plant pathogenic fungi, Botrytis cinerea (MIC= 5 μg/mL), Fusarium moniliforme and Pythium ultimum .
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-
-
- HY-121405
-
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antibiotic K16
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Antibiotic
Parasite
|
Infection
|
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Malonomicin (Antibiotic K16) is an antibiotic with anti-protozoa and anti-trypanosome activities. Malonomicin also shows anti-trypanosome activity in vivo .
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-
-
- HY-120333
-
|
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Antibiotic
Fungal
Bacterial
|
Infection
|
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Antibiotic PF 1052 is an antibiotic extracted from a natural product library. Antibiotic PF 1052 has an inhibitory effect on murine neutrophil migration .
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-
-
- HY-113602
-
|
antibiotic 273 A1-beta
|
Antibiotic
Bacterial
|
Infection
|
|
Paldimycin B (Antibiotic 273 A1-beta) is a powerful semi-synthetic antibiotic with antibacterial activity against S. aureus and coagulase-negative staphylococci .
|
-
-
- HY-165272
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Antibiotic SF-2132 is a peptide antibiotic identified in Nocardiopsis sp., which exhibits inhibitory activity against β-lactam antibiotic-resistant strains, such as Pseudomonas and Escherichia .
|
-
-
- HY-113622
-
|
Palmarumycin C13; Diepoxin ζ; antibiotic Sch53514
|
Fungal
Antibiotic
|
Infection
|
|
Cladospirone bisepoxide is a metabolite that isolated from cultures of a fungus. Cladospirone bisepoxide displays selective antibiotic activity against several bacteria and fungi and inhibits germinations of Lepidium sativum at low concentrations .
|
-
-
- HY-136822
-
-
-
- HY-14366
-
|
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Antibiotic
Bacterial
|
Infection
|
|
Antibiotic A-338533, an antibiotic, can be isolated from Streptomyces strain. Antibiotic A-338533 has anti-bacterial activity against Staphylococcus aureus, Mycoplasma gallisepticum with MIC values of 2 μg/mL and ≤1.56 μg/mL, respectively .
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-
-
- HY-B1222A
-
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antibiotic 6640; Rickamicin
|
Bacterial
Antibiotic
|
Infection
|
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Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria .
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-
-
- HY-128488
-
-
-
- HY-N12913
-
|
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Antibiotic
Fungal
|
Infection
|
|
Antibiotic WB is an antibioticwith antifungal activity and can be isolated from the soil fungus strain 38 .
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-
-
- HY-A0097A
-
|
antibiotic MDL-507 sodium; MDL-507 sodium
|
Antibiotic
HIV
SARS-CoV
|
Infection
|
|
Teicoplanin sodium is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin sodium shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity .
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-
-
- HY-12820
-
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antibiotic-202
|
Bacterial
Antibiotic
|
Infection
|
|
Sibofimloc (Antibiotic-202) is a first-in-class, gut-restricted, orally active FimH adhesion inhibitor extracted from patent WO2014100158A1, Compound Example 202. Sibofimloc has anti-bacterial infective activity. Sibofimloc is developed for inflammatory bowel disease (IBD) .
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- HY-159930
-
|
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Antibiotic
|
Infection
|
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Antibiotic adjuvant 3 (compound 8g) is an antibiotic adjuvant with potent colistin-potentiating activity and low mammalian toxicity. Antibiotic adjuvant 3 has minimum re-sensitizing concentration of 0.25 μg/mL agnist of Escherichia coli AR-0493 .
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- HY-159929
-
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Antibiotic
|
Infection
|
|
Antibiotic adjuvant 2 (compound 5q) is an antibiotic adjuvant with potent colistin-potentiating activity and low mammalian toxicity. Antibiotic adjuvant 2 has minimum re-sensitizing concentration of 0.125 μg/mL agnist of Escherichia coli AR-0493 .
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- HY-136666
-
|
|
Bacterial
|
Others
|
|
Antibiotic AC4437 is a compound with antimicrobial activity isolated from specific soil microorganisms and has an inhibitory effect on Bacillus subtilis.
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-
-
- HY-N1724
-
|
antibiotic X 4357B; Folimycin; X 4357B
|
Proton Pump
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
Cancer
|
|
Concanamycin A (Folimycin; Antibiotic X 4357B) is a macrolide antibiotic, a vacuolar type H +-ATPase (V-ATPase) inhibitor. Concanamycin A is also an inhibitor of lysosomal acidification, can be used to T cell-mediated inflammation research - .
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-
-
- HY-126826
-
-
-
- HY-112661
-
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antibiotic PC-766B
|
Antibiotic
Bacterial
Fungal
|
Infection
Cancer
|
|
PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na +, K +-ATPase .
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-
-
- HY-P2047
-
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antibiotic FR-900201
|
Antibiotic
Bacterial
|
Infection
|
|
Lavendomycin is a peptide antibiotic from Streptomyces. Lavendomycin inhibits Gram-positive bacteria .
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-
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- HY-106590
-
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antibiotic KA 5685
|
Bacterial
|
Infection
|
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Saccharocin (Antibiotic KA 5685) is effective against Gram-positive and negative bacteria, and also against aminoglycoside antibiotic-resistant bacteria .
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-
-
- HY-161870
-
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Antibiotic
|
Infection
|
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Antibiotic adjuvant 1 (compound 3e) is an antibiotic adjuvant that presents insufficient antibacterial activity (MIC > 128 µg/mL) and potentiate the activity of Cloxacillin (HY-B0466A)(66-fold) with synergistic effect .
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- HY-124111
-
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antibiotic YC 17
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Antibiotic
Bacterial
|
Infection
|
|
10-Deoxymethymycin (Antibiotic YC 17) displays antibiotic activity against Gram positive bacteria .
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-
-
- HY-P2450
-
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antibiotic P168
|
Fungal
Antibiotic
|
Infection
Cancer
|
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Leucinostatin A (Antibiotic P168) is a nonapeptide exerting a remarkable activity especially against Candida albicans and Cryptococcus neoformans. Leucinostatin A is a hydrophobic nonapeptide antibiotic. Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells. Antiprotozoal activies .
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-
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- HY-19965
-
|
antibiotic UK 2A
|
Antibiotic
Fungal
|
Infection
|
|
UK-2A (Antibiotic UK 2A) is a potent antifungal antibiotic. UK-2A shows antifungal activity .
|
-
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- HY-12820R
-
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antibiotic-202 (Standard)
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Bacterial
Antibiotic
|
Infection
|
|
Sibofimloc (Standard) is the analytical standard of Sibofimloc. This product is intended for research and analytical applications. Sibofimloc (Antibiotic-202) is a first-in-class, gut-restricted, orally active FimH adhesion inhibitor extracted from patent WO2014100158A1, Compound Example 202. Sibofimloc has anti-bacterial infective activity. Sibofimloc is developed for inflammatory bowel disease (IBD)[1][2].
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-
-
- HY-B1908
-
|
SF-837; antibiotic SF-837
|
Bacterial
Antibiotic
|
Infection
|
|
Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria.
|
-
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- HY-N15124
-
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antibiotic SUM-3
|
Antibiotic
Bacterial
|
Infection
|
|
1-Deamino-1-hydroxysagamicin (Antibiotic SUM-3) is an aminoglycotone antibiotic. 1-Deamino-1-hydroxysagamicin has the activity against Gram-positive and Gram-negative bacteria .
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-
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- HY-108191
-
|
antibiotic 273a1α
|
Bacterial
Antibiotic
|
Infection
|
|
Paldimycin A (Antibiotic 273a1α) is an antibiotic derived from Streptomyces paulus, primarily targeting Gram-positive bacteria. Paldimycin A exerts its antibacterial effects by interfering with bacterial protein synthesis and cell membrane function .
|
-
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- HY-107767
-
|
DC 81
|
Antibiotic
Apoptosis
DNA/RNA Synthesis
|
Cancer
|
|
Antibiotic DC 81 (DC 81), an antitumor antibiotic produced by Streptomyces species, is a PBD (pyrrolo[2,1-c][1,4]benzodiazepine). Antibiotic DC 81 is potent inhibitor of nucleic acid synthesis. Antibiotic DC 81 can recognize and bind to specific sequences of DNA and form a labile covalent adduct .
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- HY-126788
-
|
DC 102
|
Antibiotic
|
Infection
Metabolic Disease
|
|
Antibiotic DC 102 is a new glycosidic pyrrole(1,4)benzodiazepine antibiotic with a MIC value of 42 μg/mL target Bacillus subtilis No. 10707. Antibiotic DC 102 has an LD50 value of 1.5mg/mL(i.p) in mouse .
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-
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- HY-103397A
-
|
antibiotic YS-02931K-β
|
Biochemical Assay Reagents
|
Infection
|
|
Dihydrokalafungin (Antibiotic YS-02931K-β) is a benzoisochromanequinone that used as a natural substrate in enzyme assays of the ActVB-ActVA system .
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- HY-19606
-
|
antibiotic MI 43-37F11
|
Interleukin Related
NO Synthase
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Cytogenin (Antibiotic MI 43-37F11) is an orally active antineoplastic antibiotic. Cytogenin regulates the inflammatory cytokine, reduces the levels of iNOS, NO and IL-6 in mouse macrophages, and exhibits antidiabetic efficacy in mice. Cytogenin inhibits growth of Ehrlich ascites tumor in mouse model .
|
-
-
- HY-15739
-
-
-
- HY-108718
-
|
Geneticin; antibiotic G-418
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
G-418 (Geneticin) is an aminoglycoside antibiotic with a structure similar to gentamicin. It is toxic to both eukaryotic and prokaryotic cells and works by interfering with protein synthesis .
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-
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- HY-N15125
-
|
antibiotic SU-1
|
Antibiotic
Bacterial
|
Infection
|
|
1-Deamino-1-hydroxygentamicin C2 (Antibiotic SU-1) is an aminoglycotone antibiotic. 1-Deamino-1-hydroxygentamicin C2 has the activity against Gram-positive and Gram-negative bacteria .
|
-
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- HY-123720
-
|
antibiotic EV22; L-660631
|
Antibiotic
Fungal
|
Infection
|
|
Sch 31828 is a novel antifungal antibiotic, with mean MICs against Candida of 0.034 /g/mL .
|
-
-
- HY-N15126
-
|
antibiotic SU-2
|
Antibiotic
Bacterial
|
Infection
|
|
1-Deamino-1-hydroxygentamicin C1a (Antibiotic SU-2) is an aminoglycotone antibiotic. 1-Deamino-1-hydroxygentamicin C1a has the activity against Gram-positive and Gram-negative bacteria .
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-
-
- HY-122507
-
|
A 28695A; antibiotic A 28695A
|
Antibiotic
|
Infection
|
|
Septamycin (A 28695A) is a metal complexing polyether antibiotic. Septamycin is produced by a strain of Streptomyces hygroscopicus NRRL 5678. Septamycin has anticoccidial activity .
|
-
-
- HY-A0097
-
|
antibiotic MDL-507; MDL-507
|
Bacterial
Antibiotic
|
Infection
|
|
Teicoplanin is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity .
|
-
-
- HY-108307
-
|
Gentamicin C2b sulfate; antibiotic XK-62-2 sulfate; Sagamicin sulfate
|
Antibiotic
Bacterial
|
Infection
|
|
Micronomicin sulfate (Gentamicin C2b sulfate) is an aminoglycoside antibiotic isolated from Micromonospora. Micronomicin sulfate is a broad-spectrum antibiotic close to the gentamicin-type antibiotics, exhibits a high activity against Pseudomonas, Proteus, Klebsiella pneumoniae, Serratia, etc (MIC=0.001-8.3 μg/ml) .
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-
-
- HY-117818
-
|
antibiotic DC 116
|
Antibiotic
|
Cancer
|
|
Sapurimycin is an antitumor antibiotic isolated from Streptomyces DO-116 and belongs to the capramycin family. Sapurimycin exhibits potent activity against Gram-positive bacteria and exhibits significant antitumor effects against leukemia P388 and sarcoma 180 in mouse models. In vitro studies have shown that Sapurimycin can induce single-strand breaks in supercoiled plasmid DNA .
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-
-
- HY-17561
-
|
Geneticin sulfate; antibiotic G-418 sulfate
|
Bacterial
Antibiotic
|
Infection
|
|
G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes. G-418 disulfate is commonly used as a selective agent for eukaryotic cells .
|
-
-
- HY-N6687
-
|
A-23187; antibiotic A-23187
|
Oxidative Phosphorylation
Bacterial
Fungal
Apoptosis
Autophagy
Antibiotic
|
Infection
Cancer
|
|
Calcimycin (A-23187) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin induces Ca 2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin induces apoptosis .
|
-
-
- HY-15739R
-
|
antibiotic C 15003P3 (Standard); Maytansinol isobutyrate (Standard)
|
Microtubule/Tubulin
ADC Cytotoxin
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Ansamitocin P-3 (Standard) is the analytical standard of Ansamitocin P-3. This product is intended for research and analytical applications. Ansamitocin P-3 (Antibiotic C 15003P3) is a microtubule inhibitor. Ansamitocin P-3 is a macrocyclic antitumor antibiotic.
|
-
-
- HY-118593
-
|
Madumycin II; antibiotic A 2315A
|
Antibiotic
|
Infection
|
|
A2315A (Madumycin II) is an alanine-containing streptogramin A antibiotic. A2315A is a potent peptidyl transferase center (PTC) inhibitor. A2315A inhibits the ribosome prior to the first cycle of peptide bond formation .
|
-
-
- HY-B1071
-
-
- HY-129454
-
|
antibiotic TPU-0037-A
|
Antibiotic
|
Infection
|
|
TPU-0037A is an antibiotic and a congener of lydicamycin. It inhibits the growth of Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA), B. subtilis, and M. luteus (MICs=1.56-12.5 μg/mL), but not Gram-negative E. coli, P. mirabilis, P. vulgaris, or P. aeruginosa strains (MICs=>50 μg/mL).
|
-
- HY-P10795
-
|
antibiotic NK 2
|
Parasite
Bacterial
Fungal
|
Infection
|
|
NK-2 (Antibiotic NK 2), a shortened linear amphipathic NK-Lysin analog (comprising residues 39 to 65 of NK-lysin), is an antimicrobial peptide that exhibits potent activities against trypanosoma cruzi, Candida albicans, gram-positive and gram-negative bacteria. NK-2 can kill trypanosomes residing inside the human glioblastoma cell line 86HG39, left the host cells apparently unharmed .
|
-
- HY-115669
-
|
antibiotic A 15104 Y; PClP
|
Myosin
TGF-β Receptor
|
Cancer
|
|
Pentachloropseudilin (Antibiotic A 15104 Y; PClP) is a reversible and allosteric potent inhibitor of Myo1s (class 1 myosins) with IC50s range from 1 to 5 μM for mammalian class-1 myosins and greater than 90 μM for class-2 and class-5 myosins. Pentachloropseudilin is a potent inhibitor of transforming growth factor-β (TGF-β)-stimulated signaling, with an IC50 of 0.1 to 0.2 μM for TGF-β .
|
-
- HY-121716
-
|
antibiotic 2088A; LL-14I352α
|
Bacterial
|
Cancer
|
|
Pelagiomicin A is a novel phenazine antibiotic produced by the marine bacterium Pelagiobacter variabilis. The compound is unstable in water and small alcohols. The absolute structure of its major component, Pelagiomicin A, as well as the properties of minor amounts of other structures, were determined by spectroscopic data and synthesis. Pelagiomicin A is active against both Gram-positive and Gram-negative bacteria and exhibits antitumor activity in vitro and in vivo.
|
-
- HY-N6687B
-
|
A-23187 hemimagnesium; antibiotic A-23187 hemimagnesium
|
Oxidative Phosphorylation
Bacterial
Fungal
Apoptosis
Autophagy
|
Infection
Cancer
|
|
Calcimycin (A-23187) hemimagnesium is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin hemimagnesium induces Ca 2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin hemimagnesium inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin hemimagnesium also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin hemimagnesium induces apoptosis .
|
-
- HY-N6687A
-
|
A-23187 hemicalcium salt; antibiotic A-23187 hemicalcium salt
|
Oxidative Phosphorylation
Bacterial
Fungal
Apoptosis
Autophagy
Antibiotic
|
Infection
Cancer
|
|
Calcimycin hemicalcium salt (A-23187 hemicalcium salt) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin hemicalcium salt induces Ca 2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin hemicalcium salt inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin hemicalcium salt also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin hemicalcium salt induces apoptosis .
|
-
- HY-130340
-
|
Teichomycin A3 factor 1; antibiotic L 17054
|
Antibiotic
|
Infection
|
|
Teicoplanin A3-1 is a degradation product of teicoplanins A2-1 to 5 (Item Nos. 20187, 20188, 20189, 20192). Teicoplanins are glycopeptide antibiotics produced by A. teichomyceticus that are broadly effective against Gram-positive bacteria in vitro.
|
-
- HY-100833R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cabozantinib (S-malate) (Standard) is the analytical standard of Cabozantinib (S-malate). This product is intended for research and analytical applications. Cabozantinib S-malate (XL184 S-malate) is a potent multiple receptor tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.
|
-
- HY-N6732
-
|
SF2370; antibiotic K 252a; antibiotic SF 2370
|
PKC
PKA
CaMK
Trk Receptor
Autophagy
Antibiotic
|
Infection
Inflammation/Immunology
|
|
K-252a, a staurosporine analog, inhibits protein kinase, with IC50 values of 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca 2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively . K-252a is a potent inhibitor (IC50 of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, the product of the trk protooncogene .
|
-
- HY-126699
-
|
antibiotic TAN 420D
|
Bacterial
|
Infection
|
|
Herbimycin C is a bacterial metabolite originally isolated from S. hygroscopicus. It is cytotoxic to HeLa and Ehrlich cells (IC50s=7.3 and 1.2 μg/mL, respectively).
|
-
- HY-117986
-
|
antibiotic AB3217A
|
Parasite
|
Infection
|
|
AB 3217-A, an anti-mite substance, can be isolated from the fermentation broth of a streptomycete strain .
|
-
- HY-P2331
-
|
antibiotic A 3802-IV-3; Gardimycin
|
Antibiotic
|
Infection
|
|
Actagardin is a tetracyclic lantibiotic produced by several species of Actinoplanes. It is composed of macrocyclic rings formed by thioether bridges. Actagardin preferably targets Gram-positive bacteria, inhibiting the synthesis of peptidoglycan.
|
-
- HY-15141
-
|
antibiotic AM-2282; STS; AM-2282
|
PKC
PKA
Apoptosis
Bacterial
Fungal
Antibiotic
|
Infection
Cancer
|
|
Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. Staurosporine also inhibits TAOK2 with an IC50 of 3 μM. Staurosporine is an apoptosis inducer .
|
-
- HY-129694
-
|
Ro 21-6150; antibiotic A-130-A
|
β-catenin
CDK
Reactive Oxygen Species
|
Cancer
|
|
Lenoremycin (Ro 21-6150) is a microbial metabolite. Lenoremycin decreases β-catenin and cyclin D1 proteins levels. Lenoremycin decreases cancer stem cells (CSCs) populations via inducing reactive oxygen species production .
|
-
- HY-101938
-
-
- HY-114551
-
|
Racemomycin C; antibiotic S15-1B
|
Bacterial
Fungal
|
Infection
|
|
Racemomycin C has broad spectrum antibacterial activity and antifungal effect, and it can inhibit PR-8 of influenza virus in tissue culture .
|
-
- HY-104051
-
-
- HY-105393
-
|
antibiotic LB 10517 sodium
|
Bacterial
|
Infection
|
LB 10517 (sodium) is a type of cephalosporin. LB 10517 (sodium) has broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria, including Enterobacteriaceae, Pseudomonas aeruginosa, Staphylococcus, and Streptococcus .
|
-
- HY-15141G
-
|
antibiotic AM-2282; STS; AM-2282
|
PKC
|
Infection
Cancer
|
|
Staurosporine (AM-2282) (GMP) is Staurosporine (HY-15141) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases .
|
-
- HY-134090
-
|
antibiotic TS 885; NSC 248958
|
Bacterial
VSV
|
Infection
|
|
9-Methylstreptimidone is a microbial metabolite originally isolated from Streptomyces sp. S-885 that has antifungal and antiviral activities. It is active against several fungi, including S. sake, S. fragilis, R. rubra, T. rubra, and C. albidus (MICs=4-20 μg/mL) and has antiviral activity against poliovirus, vesicular stomatitis virus (VSV), and Newcastle disease virus (NDV) in vitro (MIC=0.02 μg/mL for all). 9-Methylstreptimidone increases survival in mouse models of infection with influenza A2 (H2N2) or C. albicans when administered prior to infection.
|
-
- HY-15141R
-
|
antibiotic AM-2282 (Standard); STS (Standard); AM-2282 (Standard)
|
PKC
PKA
Apoptosis
Bacterial
Fungal
Antibiotic
|
Infection
Cancer
|
|
Staurosporine (Standard) is the analytical standard of Staurosporine. This product is intended for research and analytical applications. Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. Staurosporine also inhibits TAOK2 with an IC50 of 3 μM. Staurosporine is an apoptosis inducer[1][2][3][4][5].
|
-
- HY-111221
-
-
- HY-B1071A
-
-
- HY-16384
-
|
antibiotic L 156602; PD 124966
|
Complement System
|
Inflammation/Immunology
|
|
L-156602 is a C5a receptor antagonist. L-156602 inhibits inflammation, and the migration of monocytes and neutrophils to the infiltrating site in mouse inflammatory models. L-156602 suppresses the efferent phase of delayed-type hypersensitivity (DTH) .
|
-
- HY-171233
-
|
|
Bacterial
|
Infection
|
|
MRSA antibiotic 2 (compound 2) shows MIC of 2 μg/mL for S. aureus (MRSA). MRSA antibiotic 2 selectively target Gram-positive bacteria over Gram-negative bacteria and human cells .
|
-
- HY-135181
-
-
- HY-120009
-
-
- HY-126479
-
-
- HY-129312
-
-
- HY-N14004
-
-
- HY-N14003
-
-
- HY-111134
-
|
|
Antibiotic
|
Infection
Cancer
|
|
TAN 420C is an antibiotic that shows a strong cytotoxic activity against the lymphocytic leukemia .
|
-
- HY-126696
-
-
- HY-P1612
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Hormaomycin is a potent and selective macrocyc antibiotic agent. Hormaomycin has broad-spectrum antibiotic activity against numerous Gram-positive .
|
-
- HY-122285
-
-
- HY-163321
-
|
|
Antibiotic
|
Infection
|
|
DapE-IN-1 (compound 3y) is a diaminopimelate desuccinylase (DapE) inhibitor and a potentially potent antibiotic .
|
-
- HY-117566
-
-
- HY-N15350
-
|
|
Fungal
Antibiotic
|
Infection
|
|
Demethylblasticidin S is an antifungal antibiotic that can be synthesized by Streptomyces griseochromogenes .
|
-
- HY-124262
-
-
- HY-125539
-
|
|
Fungal
Antibiotic
|
Infection
|
|
Roridin E is an antibiotic that has cell-inhibiting and fungicidal activities similar to verrucarin .
|
-
- HY-113582
-
-
- HY-P5728
-
-
- HY-122327
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Nodusmicin is a macrolide antibiotic against antibiotic-susceptible and -resistant S. aureus with MIC values of 125, 250 and 250 μg/mL for UC-76, UC-6685, and UC-6690 strains, respectively .
|
-
- HY-120579
-
-
- HY-113562
-
-
- HY-130069
-
-
- HY-N9425
-
-
- HY-157987
-
|
|
Bacterial
|
Infection
|
|
MBX3135 is an efflux pump inhibitor which can enhance the effect of antibiotics through the AcrB target of bacteria. MBX3135 can be used for research of infection and antibiotics .
|
-
- HY-121395
-
|
|
Antibiotic
Fungal
|
Infection
|
Lepiochlorin is an antibiotic metabolite produced by a fungus (Lepiota species) that is cultivated by ants, which can prevent fungal contamination .
|
-
- HY-P5725
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Aurein 2.1 is an antibiotic peptide that can be found in the Australian Bell Frogs Litoria aurea and Litoria raniformis .
|
-
- HY-125720
-
|
|
Antibiotic
|
Infection
|
|
A-39183A is an antibiotic that shows significant cytotoxicity to HeLa cells, with an IC50 value of 1.8 μM .
|
-
- HY-126605
-
|
|
Bacterial
|
Infection
|
|
Trinactin is a macrotetrolide antibiotic. Trinactin also is a cation carrier .
|
-
- HY-129342
-
|
|
Antibiotic
|
Infection
|
|
Lincomycin B is an antibiotic that can be isolated from Streptomyces lincolnensis .
|
-
- HY-122415
-
|
|
Antibiotic
|
Infection
|
|
Tunicamine is a high carbohydrate antibiotic that is part of the structure of Tunicamycin. Tunicamycin is a nucleoside antibiotic and a reversible polyprenol-phosphate inhibitor .
|
-
- HY-B1682
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Loracarbef, a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class .
|
-
- HY-B1682A
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Loracarbef hydrate, a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class .
|
-
- HY-P5726
-
|
|
Antibiotic
|
Cancer
|
|
Aurein 1.2 is an active amphibian antibiotic peptide with antibiotic and anticancer activities .
|
-
- HY-113945
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Abbeymycin is an antibiotic derived from the actinobacterium Streptomyces sp. AB-999F-52. Abbeymycin is a specifically acting antibiotic with antimicrobial activity, primarily targeting anaerobic bacteria. Abbeymycin is employed in research concerning antibiotic discovery and screening .
|
-
- HY-118992
-
|
X 5108; Goldinomycin
|
Antibiotic
Bacterial
|
Infection
|
|
Aurodox (X 5108) is an antibiotic obtained from a streptomyces variant, Aurodox can against a number of gram-positive bacteria. Aurodox shows a very low toxicity in mice and promoted poultry growth .
|
-
- HY-W439855
-
-
- HY-N13149
-
-
- HY-105113
-
-
- HY-N13147
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Tetromycin C5 is an antibiotic, that exhibits board-spectrum antibacterial activity against gram-positive bacteria and their drug-resistant bacteria .
|
-
- HY-B0273S1
-
-
- HY-24463
-
|
|
Antibiotic
|
Others
|
|
3,4-Di-O-acetyl-L-fucal is the reactant for synthesis antibiotics (extracted from patent WO1999026956A1) .
|
-
- HY-17028A
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
(Rac)-Besifloxacin hydrochloride is the enantiomer of Besifloxacin hydrochloride. Besifloxacin hydrochloride is a broad-spectrum fourth-generation fluoroquinolone antibiotic .
|
-
- HY-125358
-
|
MK 2266 B
|
Antibiotic
Fungal
|
Infection
|
|
Dactylfungin B (MK 2266 B) is an antifungal antibiotic that is active against Candida pseudotropicalis and other fungi, with an MIC value at <10 μg/mL .
|
-
- HY-126867
-
-
- HY-135532
-
|
|
Antibiotic
|
Infection
|
|
Amoxicillin-clavulanate potassium is an antibiotic. Amoxicillin-clavulanate potassium has the potential for the research of various bacterial infection .
|
-
- HY-119405
-
-
- HY-115843
-
-
- HY-126602
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Kinamycin B is an antibiotic found in Streptomyces murayamaensis of the genus Streptomyces that exhibits antifungal activity .
|
-
- HY-N8252
-
|
|
Antibiotic
|
Infection
|
|
Xanthoquinodin A1 is an anticoccidial antibiotic having a new xanthone-anthraquinone conjugate system .
|
-
- HY-125732
-
|
|
Antibiotic
|
Infection
|
|
Decarestrictine D exhibits inhibitory activity against cholesterol levels. Decarestrictine D is utilized as receptor for glycosylation reactions to synthesize novel hybrid antibiotics .
|
-
- HY-N3300
-
-
- HY-123350
-
|
|
Antibiotic
|
Infection
|
|
Saroaspidin B, a dimer of a phloroglucinol moiety, is an antibiotic compound .
|
-
- HY-161018
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
CF3–K11 is a stable antibiotic with antibacterial activity. CF3–K11 has strong antibacterial activity against Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus (MRSA).
|
-
- HY-126577
-
|
|
Antibiotic
Bacterial
|
|
|
Dactylocycline B, an antibiotic, is active against gram-positive bacteria, including tetracycline-resistant bacteria .
|
-
- HY-113629R
-
|
|
Drug Metabolite
|
Infection
|
|
Cefixime (trihydrate) (Standard) is the analytical standard of Cefixime (trihydrate). This product is intended for research and analytical applications. Cefixime trihydrate (FR-17027 trihydrate) is an antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections .
|
-
- HY-126838
-
|
|
Antibiotic
|
Infection
|
|
Lavendofuseomycin is a macrolide pentaene antibiotic that can be utilized for antibacterial research .
|
-
- HY-123552
-
|
|
Antibiotic
|
Infection
|
|
RK-1441A is a pyrrolobenzodiazepine antibiotic with antibacteriophage activity .
|
-
- HY-126559
-
|
Mycotrienin I
|
Fungal
Antibiotic
|
Infection
|
|
Ansatrienin A is an antifungal antibiotic that can be isolated from Streptomyces collinus .
|
-
- HY-121050
-
|
W7783
|
Antibiotic
Fungal
|
Infection
|
|
Ambruticin (W7783) is an orally active and potent antifungal antibiotic. Ambruticin represents a class of antibiotics, that can be isolated from a strain of Polyangium cellulosum var. fulvum, a bacterium belonging to the class Myxobacteriales. Ambruticin is a cyclopropyl-polyene-pyran acid and is active against fungi .
|
-
- HY-N14353
-
|
|
Fungal
|
Infection
|
|
Papulacandins A is an antibiotic. Papulacandins A can be found in the fungus Papularia sphaerosperma. Papulacandins A has strong anti-yeast effect, but has no effect on filamentous fungi, bacteria and protozoa .
|
-
- HY-P3884
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Arylomycin A2, an antibiotic (Antibiotic), is a lipopeptide type I signal peptidase (SPase I) inhibitor. Arylomycin A2 has antibacterial effects .
|
-
- HY-138083
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Parvodicin C2 is a glycopeptide antibiotic that can be isolated from parvosata. Parvodicin C2 has antibacterial activity .
|
-
- HY-136428
-
|
|
Drug Metabolite
|
Cancer
|
|
Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound .
|
-
- HY-121347
-
-
- HY-B0220S3
-
|
|
Bacterial
|
Infection
|
|
Erythromycin- 13C2 is a macrolide antibiotic that can be used to treat respiratory infections, skin infections, and chlamydia infections .
|
-
- HY-A0153
-
-
- HY-A0153A
-
|
Cefapirin sodium
|
Bacterial
Antibiotic
|
Infection
|
|
Cephapirin sodium (Cefapirin sodium) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity .
|
-
- HY-116272
-
-
- HY-111331
-
|
|
Antibiotic
Hexokinase
|
Infection
|
|
Germicidin B is an antibiotic with bactericidal properties. Germicidin B can inhibit hexokinase II, with an IC50 of 25.16 μM .
|
-
- HY-150523
-
|
|
Antibiotic
|
Infection
|
|
Ristocetin is a glycopeptide antibiotic. Ristocetin induces platelet aggregation. Ristocetin can be used for Research of Von Willebrand’s disease .
|
-
- HY-B0276
-
|
2-Ethylthioisonicotinamide
|
Bacterial
Antibiotic
|
Infection
|
|
Ethionamide (2-ethylthioisonicotinamide) is a second-line anti-tuberculosis antibiotic with antibacterial effect and oral activity .
|
-
- HY-N15367
-
|
|
Antibiotic
|
Infection
|
|
Aklaviketone is a bacterial metabolite found in strain S 383 of Streptomyces galilaeus. Aklaviketone can be used in the biosynthetic pathway of anthracycline antibiotics .
|
-
- HY-126746
-
|
|
Antibiotic
|
Infection
|
|
Corynecin I is an antibiotic produced by Corynebacterium hydrocarboclastus, and its precursor (D-(-) threo-p-amino phenyl serinol-N-acetylamine) has a minimal inhibitory effect on the synthesis of Corynecin from mevalonic acid .
|
-
- HY-112663
-
|
|
Antibiotic
|
Infection
|
|
Monazomycin is a polyene-like antibiotic produced by Streptomyces. Monazomycin molecular weight is about 1200 .
|
-
- HY-17565A
-
|
|
DNA/RNA Synthesis
Antibiotic
|
Cancer
|
|
Bleomycin hydrochloride is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin hydrochloride is an antitumor antibiotic .
|
-
- HY-16035
-
|
|
DNA/RNA Synthesis
Antibiotic
|
Cancer
|
|
Alatrofloxacin, the parenteral proagent of Trovafloxacin, is a fluoronaphthyridone which contains an L-alanyl-L-alanyl salt. Alatrofloxacin functions similar to other fluoroquinolone antibiotics in that it not only has antibiotic activity to kill invading organisms by interfering with DNA synthesis, it possesses immunosuppressive activity .
|
-
- HY-125395
-
-
- HY-P2599
-
-
- HY-126406
-
-
- HY-119604
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cafamycin is a polyether antibiotic active against gram-positive bacteria, including Staphylococcus aureus. Cafamycin also demonstrates insecticidal and antiprotozoal activities. Cafamycin is isolated from the culture fluid of Streptomyces sp., an organism producing the anthracycline antibiotic galtamycin .
|
-
- HY-15087A
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Spergualin trihydrochloride is a natural occurring antibiotic initially identified from culture filtrates of Bacillus laterosporus BMG162-aF2 .
|
-
- HY-130339
-
-
- HY-P10211
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Virgilagicin is a Gram-positive active antibiotic that has a dual polyprenyl phosphate binding mechanism that impedes resistance development .
|
-
- HY-130338
-
-
- HY-157492
-
|
|
Bacterial
|
Infection
|
|
RO7075573 (compound 3) is an antibiotics that targets the lipopolysaccharide (LPS) transport machine in Acinetobacter. RO7075573 protects mice from A. baumannii infections .
|
-
- HY-105981
-
|
GR 50692; TA 5901
|
Antibiotic
Bacterial
|
Infection
|
|
Cefempidone (GR 50692) is a third-generation cephalosporin antibiotic. Cefempidone exerts antibacterial activity by inhibiting penicillin-binding proteins in bacterial cell wall synthesis .
|
-
- HY-122309
-
|
|
Antibiotic
|
Infection
|
|
A-71497 is the 3-formyl derivative of the antibiotic Tosufloxacin (HY-B1802). A-71497 can produce high plasma levels of tosufloxacin upon both oral and subcutaneous administration to mice .
|
-
- HY-123598
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Corynecin III is a Chloramphenicol (HY-B0239)-like antibiotic, which is found in Corynebacterium. Corynecin III inhibits the growth of Gram-positive and Gram-negative bacteria with MIC values of 2.6-83 μg/mL .
|
-
- HY-123635
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Nybomycin, an antibiotic, exhibits antiphage and antibacterial properties. Nybomycin binds to DNA and induces a unique morphological change to mycobacterial bacilli leading the bacterial cell death .
|
-
- HY-125707
-
|
MCH 210
|
Proton Pump
Antibiotic
|
Infection
|
|
Concanamycin B is a macrolide antibiotic，which can inhibit the cavitation type H+-ATPases，and the IC50 value is 5 nM .
|
-
- HY-169175
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
CN-CC-861 is a broad-spectrum antibiotic. CN-CC-861 shows antibiotic activities for susceptible and multidrug-resistant bacteria. CN-CC-861 shows potent bactericidal activity in vivo .
|
-
- HY-A0246A
-
-
- HY-147359
-
|
|
Antibiotic
Apoptosis
|
Cancer
|
|
Boanmycin is an antibiotic with antitumor activity that induces cellular senescence and apoptosis .
|
-
- HY-A0246
-
-
- HY-N10469
-
|
Phleomycin F
|
Antibiotic
|
Cancer
|
|
Bleomycin B4 (Phleomycin F) is an antibiotic. Bleomycin B4 has antitumor activity. Bleomycin B4 can be used for the research of cancer .
|
-
- HY-111019A
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
SCH 34343 sodium is a potent β-lactam Antibiotic with bactericidal activity against Streptococcus pneumoniae, viridans streptococci, streptococci of groups A, B, C and G, and Str. bovis .
|
-
- HY-137324
-
|
|
Drug Metabolite
Antibiotic
|
Infection
|
|
α-Apooxytetracycline is a degradation product of Oxytetracycline (HY-B0275). Oxytetracycline is an antibiotic belonging to the tetracycline class .
|
-
- HY-121780
-
|
|
Fungal
Antibiotic
|
Infection
|
|
Aranorosin, a potent antifungal antibiotic, has been isolated from the culture filtrate and mycelium of a strain of Pseudoarachniotus roseus Kuehn .
|
-
- HY-135285
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Rifamexil is an antibiotic Rifamycin (HY-B1907A) derivative that is active against Mycobacterium avium complex and other mycobacteria .
|
-
- HY-135393S
-
|
|
Isotope-Labeled Compounds
Bacterial
|
Infection
|
|
Sulfadimethoxypyrimidine-d4 is a deuterium labeled Sulfadimethoxypyrimidine. Sulfadimethoxypyrimidine is a sulfonamide antibiotic with a broad-spectrum antibacterial effect[1].
|
-
- HY-105267
-
|
|
Fungal
Antibiotic
|
Infection
|
|
LY 121019 is a semi-synthetic antifungal antibiotic with strong anticandida activity with MIC50 value of 0.625 μg/mL .
|
-
- HY-129034
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Ramoplanin is a broad-spectrum lipoglycodepsipeptide antibiotic derived from the Actinoplanes spp with with activity against gram-positive bacteria .
|
-
- HY-N6705
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Tropodithietic acid is a sulfur-containing antibiotic produced by the marine bacterium Phaeobacter inhibens. Tropodithietic acid exhibits a strong antibiotic activity against a broad spectrum of bacteria including alpha- and gammaproteobacteria, flavobacteria and actinobacteria .
|
-
- HY-B1459
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Dicloxacillin sodium is a β-lactam antibiotic of the penicillin family. Dicloxacillin sodium against Gram-positive bacteria. Dicloxacillin sodium is active against β-lactamase-producing organisms such as Staphylococcus aureus .
|
-
- HY-B1459A
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Dicloxacillin is a β-lactam antibiotic of the penicillin family. Dicloxacillin against Gram-positive bacteria. Dicloxacillin is active against β-lactamase-producing organisms such as Staphylococcus aureus .
|
-
- HY-B0273
-
-
- HY-136461
-
|
Polyoxorim
|
Fungal
Antibiotic
|
Infection
|
|
Polyoxin D (Polyoxorim), a polyoxin antibiotic fungicide, is a potent chitin synthetase inhibitor .
|
-
- HY-123716
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Rubradirin B is an antibiotic, which inhibits a variety of Gram-positive bacteria and Haemophilus influenza. Rubradirin B affects the ribosome functions .
|
-
- HY-121144
-
|
Refosporen
|
Antibiotic
Bacterial
|
Infection
|
|
Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria .
|
-
- HY-P10209
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cilagicin, a dodeca-lipodepsipeptide, is a Gram-positive active antibiotic. Cilagicin has a dual polyprenyl phosphate binding mechanism that impedes resistance development .
|
-
- HY-156189
-
|
|
Antibiotic
|
Infection
|
|
CcpA-IN-1 is a Staphylococcus aureus antibiotic. CcpA-IN-1 has significant bactericidal activity (MICS=460 nM) .
|
-
- HY-B1117
-
|
MK-306
|
Bacterial
Antibiotic
Beta-lactamase
|
Infection
|
|
Cefoxitin sodium (MK-306) is a cephalosporin-class antibiotic. Cefoxitin sodium is highly stable against β-Lactamase (HY-P2998). Cefoxitin sodium has a broad spectrum of antibacterial activity, including Gram-negative and Gram-positive bacteria .
|
-
- HY-12450
-
|
Lomondomycin
|
Antibiotic
Bacterial
|
Infection
|
|
Lomofungin is a novel antibiotic produced by Streptomyces lomondensis sp.N . Lomofungin can inhibit MBNL1-CUG RNA binding. Lomofungin has antibacterial activity .
|
-
- HY-122328
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Flambamycin is an antibiotic found in Streptomyces hygroscopicus DS 23230 strain, active against Gram-positive and Gram-negative cocci and some Gram-positive rods. Flambamycin can be used in research on antibiotic screening .
|
-
- HY-129269
-
|
A-68567
|
Antibiotic
Bacterial
|
Infection
|
|
Pacidamycin I (A-68567) is a nucleoside peptide antibiotic that is highly specific for Pseudomonas aeruginosa .
|
-
- HY-N15421
-
|
|
Antibiotic
|
Infection
|
|
Leucomycin A8 is an antibiotic which can be extracted from Streptomyces kitasatoensis. Leucomycin A8 can be utilized in infection research .
|
-
- HY-13952
-
|
|
Bacterial
|
Infection
|
|
TP-808 is an intermediate used in tetracycline antibiotic synthesis with antimicrobial activity. TP-808 binds to the 30S ribosome subunit of the bacteria, preventing aminoacyl-trNA from entering the A site, thereby inhibiting the extension of the protein chain. TP-808 can be used in antibiotic drug development research .
|
-
- HY-N6783
-
|
|
Fungal
Antibiotic
|
Infection
|
|
Oligomycin C is a macrolide antibiotic produced by Streptomyces strains. Oligomycin C exhibits a strong activity against Aspergillus niger, Alternaria alternata, Botrytis cinerea and Phytophthora capsici but no activity toward bacteria .
|
-
- HY-B0337A
-
|
Sulphadimethoxine sodium
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfadimethoxine sodium (Sulphadimethoxine sodium) is a sulfonamide antibiotic used to treat many infections .
|
-
- HY-B0337
-
|
Sulphadimethoxine
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfadimethoxine (Sulphadimethoxine) is a sulfonamide antibiotic used to treat many infections .
|
-
- HY-135372
-
|
|
Drug Metabolite
|
Infection
|
|
Descarbamoyl cefuroxime is a degradation product of Cefuroxime. Descarbamoyl cefuroxime is also an intermediate for the synthesis of Cephalosporin antibiotics .
|
-
- HY-125656
-
|
Rhodosporin
|
Antibiotic
Bacterial
|
Infection
|
|
Bostrycin (Rhodosporin) is a new type of red pigment antibiotic that is primarily effective against Gram-positive bacteria .
|
-
- HY-133695
-
|
|
Drug Metabolite
|
Infection
|
|
Florfenicol amine is a metabolite of Florfenicol (HY-B1374). Florfenicol, a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases .
|
-
- HY-146646
-
|
|
Antibiotic
|
Infection
Cancer
|
|
Bleomycin A2, an antitumor antibiotic promoting DNA-degradation, is an aspartate/asparagine-β-hydroxylase (AspH) inhibitor with an IC50 of 1.47 μM .
|
-
- HY-137989A
-
|
Voriconazole oxynitride hydrochloride
|
Drug Metabolite
|
Infection
|
|
Voriconazole N-oxide (Voriconazole oxynitride) (hydrochloride) is the main metabolite of Voriconazole (HY-76200) , a widely used triazole antibiotic (fungal). Voriconazole N-oxide (hydrochloride) provides information on the patient's drug metabolism capacity .
|
-
- HY-136428R
-
|
|
Drug Metabolite
Antibiotic
|
Cancer
|
|
Desoxycarbadox (Standard) is the analytical standard of Desoxycarbadox. This product is intended for research and analytical applications. Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound .
|
-
- HY-122457
-
|
|
Antibiotic
|
Infection
|
|
Δ2,3-Doramectin is the primary pH degradation products of doramectin (HY-17035). Doramectin is a antiparasitic antibiotic .
|
-
- HY-N14350
-
|
|
Bacterial
|
|
|
Hydroxychlorothricin is an antibiotic of the chlorothricin group. Hydroxychlorothricin can be found in Streptomyces sp. K818. Hydroxychlorothricin has anti-tumor effect and can prolong the survival period of ICR mice inoculated with Ehrlich cancer cells .
|
-
- HY-B0555B
-
-
- HY-W002677
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Fluoroquinolonic acid is a bacteriostatic antibiotic. Fluoroquinolonic acid has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
|
-
- HY-B0555A
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Nafcillin sodium monohydrate, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium monohydrate can be used for the research of staphylococcal infections .
|
-
- HY-139748
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
ETX0462 is a gram-negative chemotype antibiotic. ETX0462 has potent in vitro and in vivo activity against Pseudomonas aeruginosa plus all other Gram-negative ESKAPE pathogens, Stenotrophomonas maltophilia and biothreat pathogens .
|
-
- HY-113753
-
|
|
Antibiotic
|
Infection
|
|
PDF-IN-1 (compound 2) is a potential Peptide deformylase (PDF) inhibitor. PDF-IN-1 can be used for the development of new broad-spectrum antibiotics .
|
-
- HY-W747516
-
|
|
Antibiotic
|
Infection
Cancer
|
|
Butylcycloheptylprodigiosin is the secondary metabolite produced by some bacteria, such as Streptomyces. Butylcycloheptylprodigiosin is a red-pigmented antibiotic and exhibits cytotoxicity against cancer cell MCF-7 and HDF .
|
-
- HY-A0153R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cephapirin (Standard) is the analytical standard of Cephapirin. This product is intended for research and analytical applications. Cephapirin (Cefapirin) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity .
|
-
- HY-N7151
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Aurachin D is an antibiotic. Aurachin D inhibits Gram-positive bacteria and a few funguses. Aurachin D blocks NADH oxidation in beef heart submitochondrial particles .
|
-
- HY-19581
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria .
|
-
- HY-A0153AR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cephapirin (sodium) (Standard) is the analytical standard of Cephapirin (sodium). This product is intended for research and analytical applications. Cephapirin sodium (Cefapirin sodium) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity .
|
-
- HY-125617
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
α-Lipomycin is an acyclic polyene antibiotic isolated from the gram-positive bacterium Streptomyces aureofaciens Tü117 .
|
-
- HY-A0111A
-
|
Ro15-8074/001; Deacetoxycefotaxime sodium
|
Antibiotic
Bacterial
|
Infection
|
|
Cefetamet sodium is a cephalosporin antibiotic. Cefetamet sodium has the potential for the research of both upper and lower community-acquired respiratory tract infections .
|
-
- HY-106681
-
|
Fungichromin; Pentamycin; Cogomycin
|
Antibiotic
Fungal
|
Cancer
|
|
Lagosin (Fungichromin) is a polyene macrolide antibiotic. Lagosin has demonstrated broad-spectrum antifungal activity and is impervious to agent resistance .
|
-
- HY-A0111
-
|
Ro 15-8074; Deacetoxycefotaxime
|
Antibiotic
Bacterial
|
Infection
|
|
Cefetamet is a cephalosporin antibiotic. Cefetamet has the potential for the research of both upper and lower community-acquired respiratory tract infections .
|
-
- HY-123321
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Sakyomicin A is an antibiotic isolated from Actinomycete strain M-53. Sakyomicin A is active against Gram-positive bacteria .
|
-
- HY-B0273S
-
|
|
Bacterial
|
Infection
|
|
Sulfadiazine-d4 is a deuterium labeled Sulfadiazine. Sulfadiazine is a sulfonamide antibiotic used for the treatment of toxoplasmosis[1][2].
|
-
- HY-122071
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Bicyclomycin is an antibiotic. Bicyclomycin has anti-Bacterial activity against Gram-negative bacteria except Proteus and Pseudomonas aeruginosa .
|
-
- HY-B0273A
-
-
- HY-N10174
-
|
|
Antibiotic
|
Infection
|
|
Tomaymycin is an antitumor antibiotic. Tomaymycin has antimicrobial activity against Grampositive bacteria .
|
-
- HY-P10721
-
|
|
Antibiotic
Bacterial
|
Infection
|
Plectasin is a peptide antibiotic derived from saprophytic fungi. Plectasin can kill pneumococcus in vitro. Plectasin can alleviate experimental peritonitis and pneumonia caused by pneumococcus in mice .
|
-
- HY-B1418
-
|
CL-298741; YTR-830H
|
Beta-lactamase
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Tazobactam (CL-298741) is a potent β-lactamases inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research .
|
-
- HY-A0162
-
|
|
Bacterial
|
Infection
|
|
Quinupristin is a streptogramin antibiotic. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits .
|
-
- HY-A0162A
-
|
|
Bacterial
|
Infection
|
|
Quinupristin mesylate is a streptogramin antibiotic. Quinupristin mesylate blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits .
|
-
- HY-135397
-
|
(R)-PNU-100766
|
Drug Metabolite
|
Infection
|
|
(R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis .
|
-
- HY-119789
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Albofungin (Antibiotic P-42-1) is isolated from the culture filtrate of Actinomyces tumemacerans strain INMI.P-42. Albofungin shows highly active on a wide variety of gram-positive bacteria and fungi. Albofungin shows cytotoxic to HeLa cell cultures and exhibited antitumor activity on EHRLICH ascites tumor in mice.
|
-
- HY-N7784
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Liriodenine methiodide is an antibiotic that is active against C. albicans and S. cereuisiae with antimicrobial activities .
|
-
- HY-P3511
-
|
|
Bacterial
|
Infection
|
|
Friulimicin D, a lipopeptide antibiotic, like Friulimicin B, is isolated from the actinomycete Actinoplanes friuliensis .
|
-
- HY-N11422
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Mycaminosyltylonolide is a potent antibiotic. Mycaminosyltylonolide shows antibacterial activity. Mycaminosyltylonolide inhibits luciferase synthesis .
|
-
- HY-N14763
-
|
|
Antibiotic
Fungal
|
Infection
|
|
3'-O-Decarbamoylirumamycin is a 20-membered macrolide antibiotic produced by Streptomyces subflavus subsp.Irumaensis . 3'-O-Decarbamoylirumamycin has certain inhibitory effect on plant pathogenic fungi such as Piricularia oryzae, and Sclerotinia cinerea .
|
-
- HY-117778
-
|
|
Enolase
Bacterial
Antibiotic
|
Infection
Cancer
|
|
SF2312, a natural phosphonate antibiotic (Antibiotic), is a highly potent Enolase inhibitor with IC50s of 37.9 nM and 42.5 nM for human recombinant ENO1 and ENO2, respectively. SF2312 is active against bacteria under anaerobic conditions .
|
-
- HY-W048303
-
|
|
Antibiotic
|
Infection
Cancer
|
|
L-Azatyrosine is an antitumor antibiotic isolated from Streptomyces chibaensis. L-Azatyrosine can restore normal phenotypic behavior to transformed cells bearing oncogenic Ras genes .
|
-
- HY-136502
-
|
SQ-28429
|
Antibiotic
Bacterial
|
Infection
|
|
(E)-Aztreonam (SQ-28429) is a monocyclic beta-lactam antibiotic. (E)-Aztreonam has the potential for the research of infections caused by gram-negative pathogens .
|
-
- HY-B1864C
-
|
Ksg sulfate
|
Antibiotic
Bacterial
|
Infection
|
|
Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes but not to the 50s subunit, and has anti-infective activity. Kasugamycin hydrochloride hydrate mimics mRNA nucleotides, disrupts tRNA binding and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate increases the sensitivity of mycobacteria to Rifampicin (HY-B0272) in vitro and in mouse infection models .
|
-
- HY-152965
-
-
- HY-114938
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Fumaramidmycin is an antibiotic found in Streptomyces kurssanovii NR-7GG1. Fumaramidmycin shows an antimicrobial activity against both Gram-positive and Gram-negative bacteria .
|
-
- HY-128780
-
|
SPR206
|
Bacterial
|
Infection
Cancer
|
|
Upleganan (SPR206), a polymyxin analogue, and shows antibiotic activity against multidrug resistant Gram-negative pathogen. The MIC values of Upleganan against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301 are both 0.125 mg/L .
|
-
- HY-122306
-
|
Mycotrienin II
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Ansatrienin B (Mycotrienin II) is an ansamycin antibiotic isolated from Streptomyces. Ansatrienin B is active against fungi and yeasts, but inactive against bacteria.Ansatrienin B displays antitumor antibiotic activity and can be used as an ADC Toxin .
|
-
- HY-146199
-
|
|
Bacterial
|
Infection
|
|
Antibacterial agent 108 (Compound 1h) is a potent antibacterial agent with a MIC of both 3 μM against MRSA and antibiotic resistance strains .
|
-
- HY-113799
-
-
- HY-122350
-
|
SF-2052 sulfate
|
Antibiotic
|
Infection
|
|
Dactimicin sulfate (SF-2052 sulfate) is an antibiotic produced by Dactylosporangium matsuzakiense and belongs to the fortimicin antibiotic family. Dactimicin sulfate is an aminoglycoside antibiotic containing a carboximido group and inhibits protein synthesis by binding to the 30S ribosomal subunit of bacteria. Dactimicin sulfate can be used in research on infections caused by sensitive bacteria .
|
-
- HY-N14782
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
10-Decarbomethoxyaclacinomycin A is an anthracycline antibiotic can be produced by Streptomyces galilaeus MA144-Mlt mutant strain KE303. 10-Decarbomethoxyaclacinomycin A has antibacterial activities .
|
-
- HY-B1128B
-
|
Cephamandole lithium
|
Antibiotic
Bacterial
|
Infection
|
|
Cefamandole (Cephamandole) lithium is a second-generation broad-spectrum cephalosporin antibiotic with antibacterial activity. Cefamandole lithium breaks down in the body and then releases free NMTT, which can lead to low prothrombinemia .
|
-
- HY-B1459AR
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Dicloxacillin (Standard) is the analytical standard of Dicloxacillin. This product is intended for research and analytical applications. Dicloxacillin is a β-lactam antibiotic of the penicillin family. Dicloxacillin against Gram-positive bacteria. Dicloxacillin is active against β-lactamase-producing organisms such as Staphylococcus aureus .
|
-
- HY-N8386
-
|
|
Antibiotic
|
Infection
Cancer
|
|
Berkeleylactone F is an antibiotic macrolide compound. Berkeleylactone F showed modest inhibition of CCRF-CEM leukemia cells .
|
-
- HY-W743988
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cilastatin ammonium salt is an antibiotic that is relatively effective against Gram-positive cocci with a half-life of 3-4 h .
|
-
- HY-147429A
-
|
Abx MCP TFA; RG6006 TFA
|
Antibiotic
Bacterial
|
Infection
|
|
Zosurabalpin TFA is a tethered macrocyclic peptide antibiotic, acting specifically on A. baumannii. Zosurabalpin TFA inhibits lipopolysaccharide-transport .
|
-
- HY-P2363
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Leucinostatin K is a peptide antibiotic with anti-gram-positive bacterial and fungal effects, which is found in Paecilomyces lilacinus .
|
-
- HY-A0248B
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Polymyxin B2 is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria. Polymyxin B2 kills the bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting the integrity of the cell membrane and causing the cell contents to leak. Polymyxin B2 can be used in antibiotic development and treatment of drug-resistant strains .
|
-
- HY-117660
-
|
U-10149
|
Antibiotic
Bacterial
|
Infection
|
|
Lincomycin, a lincosamide antibiotic, is an antimicrobial agent used for the research of Gram-positive bacteria infections .
|
-
- HY-126780
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Nikkomycin N is a nucleoside antibiotic, which is initially produced by Streptomyces tendae. Nikkomycin N exhibits fungicidal and insecticidal properties through inhibition of chitin synthesis .
|
-
- HY-16473
-
|
Aldesulfone disodium
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
|
|
Sulfoxone (Aldesulfone) disodium is an orally active sulphonamide antibiotic that is used against leprosy. Sulfoxone disodium can also be used in study of dermatitis herpetiformis .
|
-
- HY-170609
-
|
|
Bacterial
|
Infection
|
|
Antimicrobial agent-36 (Compound 8b) is an antimicrobial agent that significantly inhibits the level of DNA gyrase, with an IC50 value of 4.56 µM. Antimicrobial agent-36 can also be used for the preparation of nanopharmaceutical formulations, for the research and development of novel antibiotics .
|
-
- HY-122783
-
|
|
Antibiotic
|
Cancer
|
|
Isogambogic acid is an antibiotic and anti-cancer agent which efficiently elicit cell death in LLC and SK-LU-1 within a low micromolar range with IC50s of 2.26 μM and 2.02 μM. Isogambogic acid can be used for cancer research .
|
-
- HY-W127442
-
|
Ethyl 2-Ethylbutyrate
|
Bacterial
|
Others
|
|
Etzadroxil (Ethyl 2-Ethylbutyrate) is a volatile ester compound. Sulopenem Etzadroxil is an orally available ester proagent form of Sulopenem, an antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria .
|
-
- HY-125060
-
-
- HY-125419
-
|
|
Antibiotic
Parasite
Bacterial
|
Infection
|
|
Amythiamicin B is a trisubstituted pyridine thiopeptide with antibiotic properties against Gram-positive bacteria and activity against Plasmodium falciparum .
|
-
- HY-B0337S1
-
|
Sulphadimethoxine-d6
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfadimethoxine-d6 is the deuterium labeled Sulfadimethoxine. Sulfadimethoxine is a sulfonamide antibiotic used to treat many infections[1].
|
-
- HY-126850
-
|
|
EGFR
|
Cancer
|
|
4-Epidoxycycline is a liver metabolite of the antibiotic doxycycline (doxycycline, HY-N0565) and doesn't have antibiotic properties in mice. 4-Epidoxycycline’s ability to regulate HER2 gene expression in vitro and in live mouse models is similar to that of doxycycline, and it shows comparable high efficacy in tumor tissues, achieving over 95% tumor regression rates .
|
-
- HY-A0248C
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Polymyxin B2 Sulfate is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria. Polymyxin B2 Sulfate kills the bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting the integrity of the cell membrane and causing the cell contents to leak. Polymyxin B2 Sulfate can be used in antibiotic development and treatment of drug-resistant strains .
|
-
- HY-P1926
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
A-54556A (ADEP 1) is an acyldepsipeptide (ADEP) antibiotic. A-54556A shows antibacterial activity against a broad range of Gram-positive bacteria .
|
-
- HY-B0213
-
|
Sulfametoxydiazine; 5-Methoxysulfadiazine
|
Antibiotic
Bacterial
|
Infection
|
|
Sulfameter (Sulfametoxydiazine; 5-Methoxysulfadiazine) is an effective long-acting sulfonamide antibiotic with antibacterial activities. Sulfameter can be used for the research of urinary tract infections and lepriasis .
|
-
- HY-N14092
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Chuangxinmycin is an antibiotic that can be isolated from Actinoplanes tsinanensis CPCC 200056. Chuangxinmycin exhibits both in vitro and in vivo antibacterial activities and can be utilized in infection research .
|
-
- HY-N12228
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Phenelfamycin E is an elfamycin-type antibiotic and is active against Gram-positive anaerobes, including Clostridium difficile. Phenelfamycin E can be used for anti-bacteria research .
|
-
- HY-145158
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Temocillin, a 6-alpha-methoxy penicillin derivative, is a semisynthetic beta-lactam antibiotic with a spectrum of activity against most aerobic Gram-negative bacteria .
|
-
- HY-124334
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
L-161240 is an antibiotic, which exhibits antibacterial activity against Escherichia coli, through inhibition of LpxC enzyme (Ki is 50 nM) .
|
-
- HY-161300
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Antibacterial agent 191 (compound 11a) is a potent semi-synthetic antibiotic. Antibacterial agent 191 exhibits preferable metabolic stability .
|
-
- HY-P1699
-
-
- HY-150520
-
|
|
Antibiotic
|
Infection
Cancer
|
|
Neomycin is an aminoglycoside antibiotic. Neomycin can be used for the research of external or internal bacterial infections, is primarily administered in veterinary medicine as a sulfate salt .
|
-
- HY-A0107
-
|
MK-801 maleate
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections .
|
-
- HY-W653871
-
|
|
Isotope-Labeled Compounds
|
Infection
|
|
Florfenicol amine-d3 is deuterated labeled Florfenicol amine. Florfenicol amine is a metabolite of Florfenicol (HY-B1374). Florfenicol, a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases .
|
-
- HY-B0273R
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Sulfadiazine (Standard) is the analytical standard of Sulfadiazine. This product is intended for research and analytical applications. Sulfadiazine is a sulfonamide antibiotic with antimalarial activity. Sulfadiazine can be used for toxoplasmosis research .
|
-
- HY-116168
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aldecalmycin is an antibiotic showing antimicrobial activities against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MICs values of 6.25-25 μg/mL .
|
-
- HY-122414
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Phosalacine is a phosphorouscontaining tripeptide herbicidal antibiotic that can be isolated from soil isolate Kitasatosporia phosalacinea KA-338. Phosalacine also shows antibacterial and antifungal activity .
|
-
- HY-B0974
-
|
Meticillin sodium
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
|
|
Methicillin sodium salt (Meticillin sodium) is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotic. Methicillin sodium salt inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. Methicillin sodium salt inhibits S. aureus with a MIC value of 2.1 μg/mL. Methicillin sodium salt can be used for the research of inflammation .
|
-
- HY-A0147
-
|
OPC-17116; dl-Grepafloxacin
|
Antibiotic
Bacterial
|
Infection
|
|
Grepafloxacin (OPC-17116) is an oral actively fluoroquinolone antibiotic with potent activity against community-acquired respiratory pathogens including Streptococcus pneumonia. Grepafloxacin has high tissue penetration and a promising pharmacodynamic profile .
|
-
- HY-N14482
-
|
|
Bacterial
|
Infection
|
|
Phenelfamycins D is an antibiotic. Phenelfamycins D can be found in Streptomyces violaceoniger AB 9991-80 and Streptomyces violaceoniger AB 1047T-33, each component of which has anti-eutrophic bacterial activity .
|
-
- HY-W714002
-
|
|
HIV
Bacterial
|
Infection
|
|
Feglymycin is a HIV replication inhibitor. Feglymycin is also an antibiotic peptide that has antibacterial activity (MIC: 32-64 μg/mL for Staphylococcus aureus) .
|
-
- HY-B0395C
-
|
DU6859a hydrate
|
Bacterial
Antibiotic
|
Infection
|
|
Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections .
|
-
- HY-136590
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Nitrosopyridine is a nitroso compound that can be used to synthesize antibiotics. 2-Nitrosopyridine can be used as a Click or Diels-Alder derivatization reagent and an excellent dienophile .
|
-
- HY-B0467
-
|
Amoxycillin sodium
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Amoxicillin (Amoxycillin) sodium is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin sodium inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
|
-
- HY-B0467A
-
|
Amoxycillin
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Amoxicillin (Amoxycillin) is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
|
-
- HY-A0147A
-
|
OPC-17116 hydrochloride; dl-Grepafloxacin hydrochloride
|
Antibiotic
Bacterial
|
Infection
|
|
Grepafloxacin (OPC-17116) hydrochloride is an oral actively fluoroquinolone antibiotic with potent activity against community-acquired respiratory pathogens including Streptococcus pneumonia. Grepafloxacin hydrochloride has high tissue penetration and a promising pharmacodynamic profile .
|
-
- HY-N15179
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Minosaminomycin is an antibiotic containing myo-inosamine that can be extracted from Streptomyces No. MA514A1. Minosaminomycin exerts antimicrobial activity against Mycobacterium smegrnatis ATCC 607 and Mycobacterium phlei (MIC= 1.56/6.25 mcg/mL) .
|
-
- HY-P10518
-
|
|
Bacterial
|
Infection
|
|
Anoplin is an antimicrobial peptide found in the venom of the solitary wasp (Anoplius samariensis). Anoplin exhibits antimicrobial activity against a wide range of bacteria, including both gram-positive and gram-negative bacteria. Anoplin can be used in the development of antibiotics .
|
-
- HY-117108
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Nocardicin A is a beta-lactam antibiotic with selective antibacterial activity. Nocardicin A has moderate antibacterial activity against a broad spectrum of Gram-negative bacteria including Proteus and Pseudomonas; it has no inhibitory effect on Staphylococcus, Mycobacterium, fungi, and yeast .
|
-
- HY-N0465
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Olaquindox, a quinoxalin derivative, is an orally active antibiotic. Olaquindox stimulates growth and decreases intestinal mucosal immunity of piglets .
|
-
- HY-W715444
-
-
- HY-139398
-
TBI-223
1 Publications Verification
|
Antibiotic
Bacterial
|
Infection
|
|
TBI-223 is an orally bioavailable oxazolidinone antibiotic and an antimicrobial. TBI-223 shows activity against Mycobacterium tuberculosis (Mtb) .
|
-
- HY-N11407
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Bagougeramine B is an orally active nucleoside antibiotic with antimicrobial activity, which is found in Bacillus circulans. Bagougeramine B inhibits the growth of Gram-positive and Gram-negative bacteria and some fungi .
|
-
- HY-N12258
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aranciamycin A is an anthracyclic antibiotic and can be isolated from Streptomyces. Aranciamycin A shows antibacterial activity against M. bovis and B. subtilis with the MIC values of 30 and 7.5 µM, respectively .
|
-
- HY-12396
-
|
2-Aminothiazole; 2-Thiazolylamine
|
Bacterial
Fungal
Virus Protease
|
Infection
|
|
Aminothiazole (2-Aminothiazole), a typical heterocyclic amine, is a precursor for the synthesis of biologically active molecules including sulfur agents, biocides, fungicides, antibiotics, dyes and chemical reaction accelerators .
|
-
- HY-B0529A
-
|
Sodium azlocillin
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Azlocillin sodium salt (Sodium azlocillin), a semisynthetic penicillin, is a broad spectrum β-lactam antibiotic. Azlocillin sodium salt shows antipseudomonal activity, and also potent against the malarial parasite Plasmodium falciparum .
|
-
- HY-N10495
-
|
|
Antibiotic
Bacterial
Topoisomerase
|
Infection
|
|
Seconeolitsine, an antibiotic, and is an inhibitor of targeting topoisomerase I (TopA). Seconeolitsine also is a new antimicrobial agent that can inhibit S. pneumoniae growth. Seconeolitsine can inhibit TopA relaxation activity with an IC50 value of 17 μM. Seconeolitsine can be used for the research of S. pneumoniae infections resistant to other antibiotics .
|
-
- HY-135562
-
-
- HY-133695R
-
|
|
Drug Metabolite
|
Infection
|
|
Florfenicol amine (Standard) is the analytical standard of Florfenicol amine. This product is intended for research and analytical applications. Florfenicol amine is a metabolite of Florfenicol (HY-B1374). Florfenicol, a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases .
|
-
- HY-19581R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Baquiloprim (Standard) is the analytical standard of Baquiloprim. This product is intended for research and analytical applications. Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria .
|
-
- HY-B0467B
-
|
Amoxycillin trihydrate
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Amoxicillin (Amoxycillin) trihydrateis an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin trihydrateis inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
|
-
- HY-B0555BR
-
|
|
Beta-lactamase
Antibiotic
Bacterial
|
Infection
|
|
Nafcillin (sodium) (Standard) is the analytical standard of Nafcillin (sodium). This product is intended for research and analytical applications. Nafcillin sodium, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium can be used for the research of staphylococcal infections .
|
-
- HY-150036
-
|
|
Antibiotic
Cholecystokinin Receptor
|
Cancer
|
|
Anthramycin, a member of the pyrolobenzodiazepine (PBD) family, is a potent antibiotic. Anthramycin has potent antitumor activity. Anthramycin can act as an potent antagonist of cholecystokinin in the central nervous system in mice .
|
-
- HY-123886
-
|
|
Antibiotic
|
Cancer
|
|
Aranciamycin (Compound 1) is an anthracycline antibiotic with collagenase inhibitory activity (IC503.7*10-7M). Aranciamycin can be used to inhibit DNA synthesis in tumor cells .
|
-
- HY-148576
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Antibacterial agent 136 (compound 3) is an antibiotic of oxadiazolones. Antibacterial agent 136 have high antibacterial potency against Staphylococcus aureus (MRSA) with a MIC50 value of 0.8 μM .
|
-
- HY-W002677R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Fluoroquinolonic acid (Standard) is the analytical standard of Fluoroquinolonic acid. This product is intended for research and analytical applications. Fluoroquinolonic acid is a bacteriostatic antibiotic. Fluoroquinolonic acid has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
|
-
- HY-B0467C
-
|
Amoxycillin arginine
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Amoxicillin (Amoxycillin) arginine is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin arginine inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
|
-
- HY-N14601
-
|
|
Bacterial
|
Cancer
|
|
Respinomycin A1 is an antibiotic. Respinomycin A1 can be found in Streptomyces sp. RK-483. Respinomycin A1 causes the differentiation of leukemic K-562 cells .
|
-
- HY-B0555AR
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Nafcillin (sodium monohydrate) (Standard) is the analytical standard of Nafcillin (sodium monohydrate). This product is intended for research and analytical applications. Nafcillin sodium monohydrate, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium monohydrate can be used for the research of staphylococcal infections .
|
-
- HY-116271
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Sperabillin C is an antibacterial antibiotic with activity against both Gram-negative and Gram-positive bacteria, including resistant strains of Pseudomonas aeruginosa and Staphylococcus aureus .
|
-
- HY-B0337AR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfadimethoxine (sodium) (Standard) is the analytical standard of Sulfadimethoxine (sodium). This product is intended for research and analytical applications. Sulfadimethoxine sodium (Sulphadimethoxine sodium) is a sulfonamide antibiotic used to treat many infections .
|
-
- HY-B0555
-
|
|
Beta-lactamase
Antibiotic
Bacterial
|
Infection
|
|
Nafcillin, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin exhibits bactericidal activity, and can be used for the research of staphylococcal infections .
|
-
- HY-P5459
-
|
|
Bacterial
Elastase
|
Infection
|
|
Elafin,also known as elafin-specific inhibitor (ESI) or skin anti-leucoprotease (SKALP), is a low molecular weight inhibitor of human neutrophil elastase (HNE) and proteinase 3 in lung. Elafin is antibiotic against Pseudomonas aeruginosa and Staphylococcus aureus .
|
-
- HY-B1418R
-
|
|
Beta-lactamase
Antibiotic
Bacterial
|
Infection
|
|
Tazobactam (Standard) is the analytical standard of Tazobactam. This product is intended for research and analytical applications. Tazobactam (CL-298741) is a potent β-lactamases inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research .
|
-
- HY-B0337S
-
|
Sulphadimethoxine-d4
|
Bacterial
|
Infection
|
|
Sulfadimethoxine-d4 is a deuterium labeled Sulfadimethoxine (Sulphadimethoxine). Sulfadimethoxine is a sulfonamide antibiotic used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections[1].
|
-
- HY-B0643
-
|
LY237216
|
Bacterial
Antibiotic
|
Infection
|
|
Dirithromycin (LY237216), a derivative of Erythromycin, is a potent and orally active semi-synthetic macrolide antibiotic. Dirithromycin is active against gram-positive bacteria, Legionella spp., Helicobacter pylori, and Chlamydia trachomatis .
|
-
- HY-A0111R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cefetamet (Standard) is the analytical standard of Cefetamet. This product is intended for research and analytical applications. Cefetamet is a cephalosporin antibiotic. Cefetamet has the potential for the research of both upper and lower community-acquired respiratory tract infections .
|
-
- HY-34588
-
|
D-(-)-4-Hydroxyphenylglycine; 4-Hydroxy-D-phenylglycine
|
Antibiotic
|
Others
|
|
D-4-Hydroxyphenylglycine (D-(-)-4-Hydroxyphenylglycine) is one of the most important raw materials used in the production of semisynthetic β-lactam antibiotics, such as Amoxicillin (HY-B0467A) and Cefadroxil (HY-B1190) .
|
-
- HY-136457
-
|
|
Drug Metabolite
|
Others
|
|
2-NP-AHD is a 2-nitrophenyl derivative of AHD (a metabolite of nitrofurans type of antibiotics), can be used as indicator of the illegal usage of nitrofuran agents .
|
-
- HY-N10470
-
|
Pingyangmycin
|
Apoptosis
|
Infection
Inflammation/Immunology
Cancer
|
|
Bleomycin A5 (Pingyangmycin) is an orally active glycopeptide antibiotics. Bleomycin A5 has a role as an antineoplastic agent, an apoptosis inducer and a bacterial metabolite .
|
-
- HY-115249
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa .
|
-
- HY-W009168
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Tazobactam sodium is an antibiotic of the beta-lactamase inhibitor class. Ceftolozane combines with Tazobactam, extends the activity of ceftolozane against many ESBL-producing Enterobacteriaceae and some Bacteroides spp..
|
-
- HY-137801
-
|
|
Parasite
|
Infection
|
|
Sesquicillin A is an insecticidal antibiotic, a fungal metabolite isolated from white plantain. Sesquicillin A inhibits the growth of A. salina brine shrimp with the MIC value of 6.25 µg/mL .
|
-
- HY-19137
-
|
KW 2189 free base
|
Antibiotic
|
Infection
Cancer
|
|
Pibrozelesin (KW 2189 free base) is the derivative of antibiotic Duocarmycin B2. Pibrozelesin exhibits antitumor activity, inhibits proliferation of cell H69 with an IC50 of 1.9 μM. Pibrozelesin induces the DNA strand breaks upon activation via carboxyl esterase .
|
-
- HY-P2223
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Hypeptin is a cyclo-deposited peptide antibiotic produced by Lysobacter sp.K5869. Hypeptin blocks bacterial cell wall biosynthesis by binding to multiple undecaprenyl pyrophosphate-containing biosynthesis intermediates，forming a stoichiometric 2:1 complex. Hypeptin has antibacterial activity .
|
-
- HY-135397R
-
|
|
Drug Metabolite
|
Infection
|
|
(R)-Linezolid (Standard) is the analytical standard of (R)-Linezolid. This product is intended for research and analytical applications. (R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis .
|
-
- HY-B1327A
-
|
7-Chlorotetracycline
|
Bacterial
Antibiotic
Parasite
|
Infection
Inflammation/Immunology
|
|
Chlortetracycline (7-Chlorotetracycline) is an orally active, effective and selectively methanogenic bacteria inhibitor with bactericidal effects. Chlortetracycline is also a antibiotic that acts by inhibiting bacterial protein synthesis. Additionally, Chlortetracycline is a specific and potent calcium ionophore antibiotic, inhibiting binding of aminoacyl-tRNA to ribosomes .
|
-
- HY-B1327
-
|
7-Chlorotetracycline hydrochloride
|
Bacterial
Antibiotic
Parasite
|
Infection
Inflammation/Immunology
|
|
Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is an orally active, effective and selectively methanogenic bacteria inhibitor with bactericidal effects. Chlortetracycline hydrochloride is also a antibiotic that acts by inhibiting bacterial protein synthesis. Additionally, Chlortetracycline hydrochloride is a specific and potent calcium ionophore antibiotic, inhibiting binding of aminoacyl-tRNA to ribosomes .
|
-
- HY-B0273AR
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Sulfadiazine (sodium) (Standard) is the analytical standard of Sulfadiazine (sodium). This product is intended for research and analytical applications. Sulfadiazine sodium is a sulfonamide?antibiotic with antimalarial activity. Sulfadiazine can be used for toxoplasmosis research .
|
-
- HY-N14922
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Nikkomycin Lx is an antibiotic that can be extracted from Streptomyces tendae TU901. Nikkomycin Lx exhibits anti-Candida Albicans activity and can be utilized in relevant research .
|
-
- HY-15993
-
|
AZD2563; AZD5847
|
Antibiotic
|
Infection
|
|
Posizolid (AZD2563), an oxazolidinone antibiotic, is developed by AstraZeneca for the study of bacterial infections. Posizolid shows very good anti-mycobacterial activity .
|
-
- HY-19647
-
|
FCE 22891; RIPM-AC; Ritipenem acetoxymethyl ester
|
Beta-lactamase
Antibiotic
Bacterial
|
Infection
|
|
Ritipenem acoxil (FCE 22891; RIPM-AC) is an oral active beta-lactamase antibiotic and can be used for study of bacterial pneumonia .
|
-
- HY-B1267
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery .
|
-
- HY-128502
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Nifurtoinol is a nitrofuran-derivative antibiotic with antibacterial effects. Nifurtoinol can be used for the research of urinary tract infections .
|
-
- HY-B0974R
-
|
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
|
|
Methicillin (sodium salt) (Standard) is the analytical standard of Methicillin (sodium salt). This product is intended for research and analytical applications. Methicillin sodium salt (Meticillin sodium) is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotic. Methicillin sodium salt inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. Methicillin sodium salt inhibits S. aureus with a MIC value of 2.1 μg/mL. Methicillin sodium salt can be used for the research of inflammation .
|
-
- HY-111190
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Thiotropocin is a tropothione Antibiotic with antibacterial activities against Gram-positive and Gram-negative bacteria, some phytopathogens and mycoplasma. Thiotropocin causes morphological changes of Proteus mirabilis and Escherichia coli .
|
-
- HY-17591
-
|
Benzylpenicillin potassium
|
Antibiotic
Bacterial
|
Infection
|
|
Penicillin G potassium is a fast-acting penicillin family antibiotic. Penicillin G potassium can be used for the research of bacterial infections that affect the blood, heart, lungs, joints, and genital areas .
|
-
- HY-136817
-
|
OM173-αA; Nanaomycin A methyl ester
|
Antibiotic
|
Infection
|
|
Nanaomycin αA (OM173-αA) is an antibiotic with antimicrobial activity. Nanaomycin αA can be isolated from a fermentation broth of Streptomyces hebeiensis derived from lichen .
|
-
- HY-128780B
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
SPR206 acetate is a polymyxin analog with antibiotic activity against Gram-negative pathogens, including multidrug-resistant (MDR) variants. SPR206 acetate has an anti-bacterial infection effect by interacting with the bacterium’s outer membrane. The MIC values of SPR206 acetate against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301 are both 0.125 mg/L .
|
-
- HY-108913
-
|
|
Beta-lactamase
Antibiotic
Bacterial
|
Infection
|
|
Nitrocefin is a highly activated, chromogenic cephalosporin derivative. Nitrocefin is a chromogenic β-lactamase substrate. Nitrocefin undergoes a distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics .
|
-
- HY-120242
-
|
|
Antibiotic
|
Infection
|
|
N-(3-Oxobutanoyl)-L-homoserine lactone (3-oxo-C4-HSL) is a carbapenem antibiotic biosynthesis autoregulator in Erwinia carotovora ATCC 39048. N-(3-Oxobutanoyl)-L-homoserine lactone induces expression of rhiI in R. leguminosarum .
|
-
- HY-116571
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
RU44790 is a monocyclic beta-lactam antibiotic that exerts potent activity against gram-negative bacteria and is highly resistant to hydrolysis by various beta-lactamases. RU44790 can be utilized in anti-bacteria research .
|
-
- HY-138179
-
|
|
Bacterial
|
Infection
|
|
7-APRA is a semi-synthetic intermediate of cephalosporin antibiotics. 7-APRA has antibacterial activity and is mainly used in the synthesis of other Cefaclor (HY-B0198) and Cefprozil (HY-B0458A) .
|
-
- HY-120838
-
|
Koningic acid
|
Caspase
|
Infection
Cancer
|
|
Heptelidic acid (Koningic acid) is a sesquiterpene antibiotic . Heptelidic acid inhibits Etoposide-induced apoptosis via downregulation of caspases . Koningic acid (KA) is a specific GAPDH inhibitor with an IC50of 90 μM .
|
-
- HY-117430
-
-
- HY-136068
-
|
|
Antibiotic
Bacterial
Autophagy
|
Infection
Cancer
|
|
DCAP is a broad-spectrum antibiotic targeting the membranes of both Gram-positive and Gram-negative bacteria. DCAP blocks autophagy at the late stages by preventing autophagolysosome maturation and interrupting the autophagic flux .
|
-
- HY-121300
-
|
(-)-TAN2162
|
Antibiotic
Bacterial
Endothelin Receptor
CGRP Receptor
|
Infection
Cancer
|
|
Kendomycin ((−)-TAN 2162) is a polyketide antibiotic with remarkable antibacterial and cancer cells cytotoxic activities. Kendomycin tends to be bacteriostatic rather than bactericidal and inhibits the growth of the methicillin-resistant Staphylococcus aureus (MRSA) strain COL at a low concentration (MIC of 5 μg/mL). Kendomycin is a potent antagonist of the endothelin receptor and a calcitonin receptor agonist which plays its role as an anti-osteoporotic agent .
|
-
- HY-B0395CR
-
|
DU6859a hydrate (Standard)
|
Bacterial
Antibiotic
|
Infection
|
|
Sitafloxacin (hydrate) (Standard) is the analytical standard of Sitafloxacin (hydrate). This product is intended for research and analytical applications. Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections .
|
-
- HY-D2437
-
|
|
Fluorescent Dye
Antibiotic
|
Cardiovascular Disease
Cancer
|
|
DOX-PEG-Cy3 (Doxorubicin-PEG-Cy3) is a Cy3 (HY-D0822) labeled DOX-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. DOX is a broad-spectrum anthracycline antibiotic with cytotoxic properties .
|
-
- HY-108913R
-
|
|
Beta-lactamase
Antibiotic
|
Infection
|
|
Nitrocefin (Standard) is the analytical standard of Nitrocefin. This product is intended for research and analytical applications. Nitrocefin is a chromogenic β-lactamase substrate that undergoes a distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics .
|
-
- HY-124438
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Herbicidin A is an adenosine-derived nucleoside antibiotic, but also is a herbicide against dicotyledonous plants. Herbicidin A can be isolated from Streptomyces scopuliridis M40 .
|
-
- HY-A0107R
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Tetracycline (Standard) is the analytical standard of Tetracycline. This product is intended for research and analytical applications. Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections .
|
-
- HY-125414
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Lydicamycin is an antibiotic isolated from the fermentation broth of an actinomycete strain identified as Streptomyces lydicus. Lydicamycin is active against Gram-positive bacteria and a certain yeast, but inactive against Gram-negative bacteria .
|
-
- HY-B0213R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Sulfameter (Standard) is the analytical standard of Sulfameter. This product is intended for research and analytical applications. Sulfameter (Sulfametoxydiazine; 5-Methoxysulfadiazine) is an effective long-acting sulfonamide antibiotic with antibacterial activities. Sulfameter can be used for the research of urinary tract infections and lepriasis .
|
-
- HY-B0522C
-
|
L-(+)-α-Aminobenzylpenicillin
|
Antibiotic
|
Infection
|
|
L-(+)-Ampicillin (L-(2S) ampicillin) is the L-isomer of Ampicillin (HY-B0522). Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .
|
-
- HY-N7151R
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Kasugamycin (hydrochloride) (Standard) is the analytical standard of Kasugamycin (hydrochloride). This product is intended for research and analytical applications. Kasugamycin hydrochloride (Ksg hydrochloride) is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin hydrochloride (Ksg hydrochloride) mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation .
|
-
- HY-N14756
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
6"'-Deamino-6"'-hydroxyneomycin B is an aminoglycosyl antibiotic that can be produced by Streptomyces fradiae UC 75 and is active against both Gram-positive and Gram-negative bacteria. 6"'-Deamino-6"'-hydroxyneomycin B can be used as an intermediate in the biosynthesis of neomycin .
|
-
- HY-149154
-
|
|
Antibiotic
|
Infection
|
|
(4S,5S,6S,12aS)-Oxytetracycline is a broad-spectrum antibiotic that can inhibit the synthesis of protein in bacteria. (4S,5S,6S,12aS)-Oxytetracycline is an important member of the bacterial aromatic polyketone family, a type of natural product with diverse structures .
|
-
- HY-131165
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
|
-
- HY-161239A
-
|
|
Antibiotic
|
Infection
Cancer
|
|
IB-96212 (compound 5) is a member of oligomycin class which can be extracted ftom the marine Micromonospora sp. L-25-ES25-008 ref. IB-96212 is an antitumor antibiotic against P-388, it also exhibits antimicrobial activity against Micrococcus luteus .
|
-
- HY-117660R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Lincomycin (Standard) is the analytical standard of Lincomycin. This product is intended for research and analytical applications. Lincomycin, a lincosamide antibiotic, is an antimicrobial agent used for the research of Gram-positive bacteria infections .
|
-
- HY-127019
-
|
|
Potassium Channel
NOD-like Receptor (NLR)
Bacterial
Antibiotic
Pyroptosis
Wnt
β-catenin
|
Infection
Cancer
|
|
Nigericin is an antibiotic derived from Streptomyces hygroscopicus that act as a K +/H + ionophore, promoting K +/H + exchange across mitochondrial membranes. Nigericin is a NLRP3 activator. Nigericin shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt/β-catenin signals. Nigericin induces pyroptosis through caspase 1/GSDMD in TNBC .
|
-
- HY-B0467AR
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Amoxicillin (Standard) is the analytical standard of Amoxicillin. This product is intended for research and analytical applications. Amoxicillin (Amoxycillin) is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
|
-
- HY-135470
-
|
P-7138
|
Antibiotic
Bacterial
|
Infection
|
|
Nifurpirinol (P-7138) is a nitroaromatic antibiotic and acts as a novel substrate for the bacterial nitroreductase (NTR) enzyme. Nifurpirinol is a more potent proagent compared to Metronidazole to trigger cell-ablation in nitroreductase expressing transgenic models .
|
-
- HY-116010
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Oleandomycin is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity. Oleandomycin inhibits protein synthesis by interference with translation of activated amino acids to nascent peptide chains on the ribosomes .
|
-
- HY-B1329
-
|
Nebramycin II sulfate
|
Bacterial
Antibiotic
|
Infection
|
|
Apramycin (EBL 1003) sulfate is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin sulfate is a potential anti-drug-resistance antibiotic .
|
-
- HY-129234
-
-
- HY-113629
-
|
D-Glucosone; D-Arabino-hexos-2-ulose
|
Drug Metabolite
|
Infection
|
|
2-Keto-D-Glucose (D-Glucosone) is a key intermediate in a secondary metabolic pathway leading to the antibiotic Cortalcerone. 2-Keto-D-Glucose is also an intermediate in the conversion of D-glucose into D-fructose. 2-Keto-D-Glucose is found in various natural sources, including fungi, algae, and shellfish .
|
-
- HY-N14758
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
6"'-Deamino-6"'-hydroxyparomomycin I is an amino glycosyl antibiotic that can be produced by Streptomyces rimosus forma paromomycinus A67 15. It is active against both Gram-positive and Gram-negative bacteria. 6"'-Deamino-6"'-hydroxyparomomycin I can be used as an intermediate in the biosynthesis of paromomycin .
|
-
- HY-19160
-
|
PA-1806; BMS 180680-01
|
Antibiotic
Bacterial
|
Infection
|
|
BMS-180680 (PA-1806) is an antibiotic, which exhibits a board-spectrum antibacterial activity against gram-negative bacteria. BMS-180680 inihibits Pseudomonas aeruginosa with MIC of 0.25 µg/ml. BMS-180680 exhibits resistance to hydrolysis by β-lactamases, such as TEM-2 and PSE enzymes .
|
-
- HY-106882
-
|
MDL 62879
|
Bacterial
Antibiotic
|
Infection
|
|
GE 2270A (MDL 62879) is an antibiotic. GE 2270A inhibits gram-positive bacteria and anaerobes by inhibiting protein synthesis. GE 2270A can be used for the research of infection .
|
-
- HY-162174
-
|
|
Beta-lactamase
Bacterial
|
Infection
|
|
MBL-IN-2 ((2R, 2R')-5αC) is an inhibitor of Metallo-β-lactamase (MBL) that can inhibit New Delhi Metallo-β-lactamase-1 (NDM-1) with an IC50 of 0.3 μM. MBL-IN-2 ((2R, 2R')-5αC) can be used for the study of resistance to β-lactam antibiotics .
|
-
- HY-113542
-
|
(+)-Blasticidin A
|
Bacterial
Antibiotic
Parasite
|
Infection
|
|
Blasticidin A ((+)-Blasticidin A) is an inhibitor of Aflatoxin production by Aspergillus parasiticus. Blasticidin A almost completely inhibits Aflatoxin production at 0.5 μM . Blasticidin A is a potent antibiotic produced by Streptomyces, inhibits Aflatoxin production without strong growth inhibition toward Aflatoxin-producing fungi .
|
-
- HY-159666
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Nystatin A1 is a polyene macrolide antifungal antibiotic that can be isolated from Streptomyces noursei. Nystatin A1 binds to ergosterol on the fungal cell membrane, increasing the permeability of the cell membrane and causing leakage of cell contents, thereby inhibiting the growth and reproduction of fungi .
|
-
- HY-B0467R
-
|
Amoxycillin sodium (Standard)
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Amoxicillin (sodium) (Standard) is the analytical standard of Amoxicillin (sodium). This product is intended for research and analytical applications. Amoxicillin (Amoxycillin) sodium is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin sodium inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth[1][2][3].
|
-
- HY-B0529AR
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Azlocillin (sodium salt) (Standard) is the analytical standard of Azlocillin (sodium salt). This product is intended for research and analytical applications. Azlocillin sodium salt (Sodium azlocillin), a semisynthetic penicillin, is a broad spectrum β-lactam antibiotic. Azlocillin sodium salt shows antipseudomonal activity, and also potent against the malarial parasite Plasmodium falciparum .
|
-
- HY-A0251
-
|
Cefpodoxime acid; R 3763
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Cefpodoxime (Cefpodoxime acid) is a potent antibiotic active against gram-positive and gram-negative bacteria. Cefpodoxime inhibits the majority of cells in microbial populations. Cefpodoxime can be used for acute otitis media, sinusitis and tosillopharyngitis research .
|
-
- HY-B0734A
-
|
SCE-963 hydrochloride
|
Antibiotic
Bacterial
|
Infection
|
|
Cefotiam (SCE-963) hydrochloride is a parenteral cephalosporin antibiotic. Cefotiam hydrochloride has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
|
-
- HY-B0734
-
|
SCE-963; Cefotiam Dihydrochloride
|
Antibiotic
Bacterial
|
Infection
|
|
Cefotiam (SCE-963) is a parenteral cephalosporin antibiotic. Cefotiam has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
|
-
- HY-B0734B
-
|
SCE-963 dihydrochloride hydrate
|
Antibiotic
Bacterial
|
Infection
|
|
Cefotiam (SCE-963) dihydrochloride hydrate is a parenteral cephalosporin antibiotic. Cefotiam dihydrochloride hydrate has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
|
-
- HY-B0278
-
|
Zinc bacitracin
|
Bacterial
Antibiotic
|
Infection
|
|
Bacitracin Zinc is a complex formed by the binding of Bacitracin (HY-107193) with zinc ions. Bacitracin Zinc is an orally active polypeptide antibiotic with bactericidal properties. Bacitracin Zinc can cause DNA and deoxyribose damage, as well as improve the gut microbiota of broiler and beef cattle .
|
-
- HY-N15337
-
|
OS-4742 A1
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Vineomycin A1 (OS-4742 A1) is an antibiotic against Gram-positive bacteria, which is found in Streptomyces matensis subsp. vineus. Vineomycin A1 also shows antitumor activity in mice. Vineomycin A1 is promising for research of skin fibrosis .
|
-
- HY-A0155
-
|
|
Antibiotic
Bacterial
|
Cancer
|
|
Viomycin is a potent antibiotic against Mycobacteria. Viomycin rapidly inhibits polypeptide chain elongation when added to purified endogenous Escherichia coli polysomes actively engaged in polypeptide synthesis .
|
-
- HY-126837
-
|
Spicamycin VIII
|
Antibiotic
|
Cancer
|
|
SPM VIII is a dodecanoyl analogue of spicamycin, a nucleoside antibiotic that contains fatty acids of various chain lengths. SPM VIII exhibits potent antitumor activity against the human gastric cancer SC-9 xenograft model .
|
-
- HY-N13154
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Malolactomycin C (compound 1) is a macrolide antifungal antibiotic isolated from Streptomyces strain KP-3144. Malolactomycin C is an effective inhibitor of Botrytis cinerea and thus controls a variety of plant diseases including gray mold .
|
-
- HY-N13278
-
|
2-Acetyl-2-decarboxamidooxytetracycline
|
Antibiotic
|
Others
|
|
2-Acetyl-2-decarboxamidotetracycline (2-Acetyl-2-decarboxamidooxytetracycline) is an antibiotic of the tetracycline type. 2-Acetyl-2-decarboxamidotetracycline shows an ultraviolet absorption spectrum which is identical with that of tetracycline or of 5-oxytetracycline above 300 mμ, a region characteristic of the BCD-ring system .
|
-
- HY-128423
-
|
Acetylisovaleryltylosin tartrate
|
Antibiotic
Bacterial
NF-κB
Apoptosis
|
Infection
Inflammation/Immunology
|
|
Tylvalosin (Acetylisovaleryltylosin) tartrate is an orally active, broad-spectrum macrolide antibiotic with antimicrobial activity. Tylvalosin tartrate is an antiviral agent useful in studying PRRSV infection. Tylvalosin tartrate induces apoptosis. Tylvalosin tartrate also has anti-inflammatory activity, relieves oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation .
|
-
- HY-129306
-
|
|
Antibiotic
Bacterial
|
Inflammation/Immunology
|
|
Gilvocarcin M is an antibiotic and can be isolated from S. gilvotanareus. Gilvocarcin M is active against S. aureus at a concentration of 32 µg/ml and inhibits growth of KB cells with the IC50 of 0.52 µg/ml. Gilvocarcin M intercalates into bacteriophage PM2 DNA .
|
-
- HY-N14959
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Deacetylravidomycin N-oxide is an antibiotic that can be produced by Streptomyces ravidus S50905. Deacetylravidomycin N-oxide is active against Gram-positive bacteria but inactive against Gram-negative bacteria. Deacetylravidomycin N-oxide has antitumor activity against P388 leukemia and methamphetamine A fibrosarcoma .
|
-
- HY-B0643R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Dirithromycin (Standard) is the analytical standard of Dirithromycin. This product is intended for research and analytical applications. Dirithromycin (LY237216), a derivative of Erythromycin, is a potent and orally active semi-synthetic macrolide antibiotic. Dirithromycin is active against gram-positive bacteria, Legionella spp., Helicobacter pylori, and Chlamydia trachomatis .
|
-
- HY-N0465R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Olaquindox (Standard) is the analytical standard of Olaquindox. This product is intended for research and analytical applications. Olaquindox, a quinoxalin derivative, is an orally active antibiotic. Olaquindox stimulates growth and decreases intestinal mucosal immunity of piglets .
|
-
- HY-19791
-
-
- HY-116060
-
|
|
Antibiotic
PKC
Bacterial
Fungal
|
Infection
|
|
RK-286D is an antibiotic and a PKC inhibitor with antimicrobial activity. RK-286D shows inhibitory activities against bleb formation induced by PDBu (HY-18985) and in vitro PKC activity .
|
-
- HY-P4848
-
|
|
Antibiotic
|
Infection
|
|
Dermcidin-1L (human) is an antibiotic peptide secreted by sweat glands. Dermcidin-1L (human) has antimicrobial activity. Dermcidin-1L (human) can be used for the research of inflammatory skin disorders .
|
-
- HY-B0136
-
|
FK-482; CI-983
|
Bacterial
Antibiotic
|
Infection
|
|
Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .
|
-
- HY-B0467BR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Amoxicillin (trihydrate) (Standard) is the analytical standard of Amoxicillin (trihydrate). This product is intended for research and analytical applications. Amoxicillin (Amoxycillin) trihydrateis an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin trihydrateis inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
|
-
- HY-Z7592
-
|
(E)-THR-221
|
Antibiotic
Bacterial
Penicillin-binding protein (PBP)
|
Infection
|
|
(E)-Cefodizime ((E)-THR-221) is an antibiotic. (E)-Cefodizime can selectively bind to penicillin-binding proteins (PBPs) and inhibit the synthesis of the bacterial cell wall, thereby exerting antibacterial activity. (E)-Cefodizime is promising for research of various bacterial infectious diseases, such as for preoperative infection prophylaxis .
|
-
- HY-13434
-
|
SQ23377
|
Calcium Channel
PKC
Bacterial
Apoptosis
Antibiotic
|
Infection
Cancer
|
|
Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC) .
|
-
- HY-155047
-
|
|
Bacterial
|
Infection
|
|
BDM91514 improves antibiotic potency through AcrB inhibition. BDM91514 prevents the growth of E. coliBW25113 (EC90: 8 μM) in the presence of 8 μg/mL Pyridomycin. BDM91514 has suitable plasma and microsomal stability .
|
-
- HY-B0518A
-
|
|
Fungal
Antibiotic
|
Infection
|
|
Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition .
|
-
- HY-N6686
-
|
Pristinamycin IIA; Ostreogrycin A
|
Bacterial
Antibiotic
|
Infection
|
|
Virginiamycin M1 (Pristinamycin IIA; Ostreogrycin A), produced by Streptomyces virginiae, is an polyunsaturated macrocyclic lactone antibiotic and acts as a component of Virginiamycin (HY-112665) . Virginiamycin M1 alone is against Staphylococcus aureus with a MIC of 0.25 μg/mL.
|
-
- HY-B1526
-
|
Thioacetazone; Amithiozone
|
Bacterial
Antibiotic
|
Infection
|
|
Thiacetazone (Thioacetazone) is a thiourea-containing antitubercular agent and is an orally active antibiotic. Thiacetazone has antibacterial action, which inhibits growth of Mycobacterium tuberculosis H37Rv with a MIC value of 0.1 μg/mL .
|
-
- HY-125117
-
|
|
DNA/RNA Synthesis
Bacterial
|
Infection
Cancer
|
|
Simocyclinone D8 is an anthracycline antibiotic with antibacterial and antitumor activity against Gram-positive bacteria. Simocyclinone D8 inhibits DNA gyrase and thus has an inhibitory effect on a variety of tumor cell lines .
|
-
- HY-129292
-
|
Quinocarmycin; DC-52; KW2152 free base
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Quinocarcin (DC-52) is a potent antitumor antibiotic. Quinocarcin inhibits Bacillus subtilis DNA, RNA and protein syntheses .
|
-
- HY-P10027
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Clovibactin is an antibiotic for drug-resistant bacterial pathogens without detectable resistance. Clovibactin TFA inihibits cell wall synthesis by targeting pyrophosphate of peptidoglycan precursors .
|
-
- HY-156198
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Bottromycin A2 is a natural antibiotic. Bottromycin A2 is active against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) .
|
-
- HY-156283
-
|
|
Antibiotic
|
Infection
|
|
Antibacterial agent 159 (Compound 6d) is an antibiotic. Antibacterial agent 159 can effective against impetigo and C. difficile infection (CDI). Antibacterial agent 159 has no observed recurrence for C. difficile and exertes a minimal impact on the beneficial gut microbiome .
|
-
- HY-115249R
-
|
|
Parasite
Antibiotic
Bacterial
|
Infection
|
|
Metronidazole acetic acid (Standard) is the analytical standard of Metronidazole acetic acid. This product is intended for research and analytical applications. Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa .
|
-
- HY-13234
-
|
|
Bacterial
Antibiotic
DNA/RNA Synthesis
|
Infection
Cancer
|
|
Rifaximin, a gastrointestinal-selective antibiotic, binds the β-subunit of bacterial DNA-dependent RNA polymerase, resulting in inhibition of bacterial RNA synthesis. Rifaximin susceptibility is higher against Gram-positive strains (MIC: 0.03-5 mg/ml) compared to Gram-negative bacteria (MIC: 8-50 mg/mL) .
|
-
- HY-138023
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Leucomycin A4 is a macrolide antibiotic that can be extracted from S. kitasatoensis. Leucomycin A4 inhibits a variety of bacteria, including S. aureus, B. subtilis, C. diphtheriae, N. gonorrhoeae, and H. influenzae (MICs = 0.15, 1.25, 0.15, 0.6, and 0.15 µg/ml, respectively) .
|
-
- HY-105237
-
|
|
Antibiotic
DNA/RNA Synthesis
|
Cancer
|
|
Esperamicin A1, as an extremely potent antitumor antibiotic, is isolated from cultures of Actinomadura verrucosospora. Esperamicin A1 can be used for the research of antitumor . Eesperamicin A1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-B1267R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfaguanidine (Standard) is the analytical standard of Sulfaguanidine. This product is intended for research and analytical applications. Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery .
|
-
- HY-18061
-
|
(Rac)-STA-21
|
STAT
Bacterial
|
Infection
Cancer
|
|
Ochromycinone ((Rac)-STA-21) is a natural antibiotic and a STAT3 inhibitor. Ochromycinone can inhibits STAT3 DNA binding activity, STAT3 dimerization. Ochromycinone has anticancer and antimicrobial activity .
|
-
- HY-N13150A
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
N-Demethylvancomycin hydrochloride is a glycopeptide antibiotic which can be found in Nocardia orientalis and active against several strains of S. aureus and S. epidermidis. N-Demethylvancomycin hydrochloride can be used for infection research .
|
-
- HY-103250
-
|
|
Antibiotic
|
Infection
|
|
PF-945863 is an orally active macrolide antibiotic that can be used for the research of multidrug resistant respiratory tract bacterial strains .
|
-
- HY-W015851
-
|
(R)-(-)-3-Hydroxybutanoic acid sodium; (R)-3-Hydroxybutyric acid sodium
|
Endogenous Metabolite
|
Metabolic Disease
|
|
(R)-3-Hydroxybutanoic acid ((R)-3-Hydroxybutyric acid) sodium is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones .
|
-
- HY-B1369A
-
|
N-Formimidoyl thienamycin; MK0787
|
Antibiotic
Bacterial
|
Infection
|
|
Imipenem (MK0787), a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
|
-
- HY-125335
-
|
Rutamycin A
|
Ras
|
Cancer
|
|
Oligomycin D (Rutamycin A) is an antibiotic. Oligomycin D can be derived from a strain of S. rutgersensis. Oligomycin D also is a potent inhibitors of K-Ras PM localization. Oligomycin D can be used for the research of various cancers .
|
-
- HY-A0294
-
|
MK-0826
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Ertapenem (MK-0826) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .
|
-
- HY-13625
-
|
L-749345; MK-826
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Ertapenem sodium (L-749345) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem sodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem sodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .
|
-
- HY-N13150
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
N-Demethylvancomycin is a glycopeptide antibiotic which can be extracted from Nocardia orientalis and active against several strains of S. aureus and S. epidermidis. N-Demethylvancomycin can be used for infection research .
|
-
- HY-17591R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Penicillin G (potassium) (Standard) is the analytical standard of Penicillin G (potassium). This product is intended for research and analytical applications. Penicillin G potassium is a fast-acting penicillin family antibiotic. Penicillin G potassium can be used for the research of bacterial infections that affect the blood, heart, lungs, joints, and genital areas .
|
-
- HY-B1329R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Apramycin (sulfate) (Standard) is the analytical standard of Apramycin (sulfate). This product is intended for research and analytical applications. Apramycin (EBL 1003) is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin is a potential anti-drug-resistance antibiotic .
|
-
- HY-B1252
-
-
- HY-106922
-
|
GV104326
|
Antibiotic
Bacterial
|
Infection
|
|
Sanfetrinem (GV104326) is a β-lactamase-stable antibiotic. Sanfetrinem has broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria .
|
-
- HY-N12654
-
|
|
Fungal
Parasite
Antibiotic
|
Infection
|
|
Irumamycin is a natural 20-membered macrolide antibiotic. Irumamycin is active in vitro against some phytopathogenic fungi . Irumamycin also shows potent antitrypanosomal activity .
|
-
- HY-B1252A
-
-
- HY-144767
-
|
|
Bacterial
|
Infection
|
|
PA3552-IN-1 (compound 15) is an antibiotic adjuvant that restores sensitivity of MDR P. aeruginosa DK2 strain to Polymyxin B. PA3552-IN-1 can reduce PA3552 expression .
|
-
- HY-B0212
-
|
|
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Sulfapyridine, a major metabolite of Sulfasalazine, is a sulfonamide antibiotic agent. Sulfapyridine inhibits recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. Sulfapyridine has antibacterial, anti-inflammatory and anti-rheumatic activities .
|
-
- HY-125104
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Mirosamicin is an antibiotic with high antibacterial activity that targets a wide range of gram-positive bacteria and certain Gram-negative bacteria as well as mycoplasma. Mirosamicin can be used for research in the field of food safety monitoring .
|
-
- HY-122494
-
|
SF-1293
|
Bacterial
|
Infection
|
|
Bilanafos is a natural organic phosphine tripeptide antibiotic metabolized by Streptomyces hydroscopius or Streptomyces viridochromeogenes. Bialaphos has antimicrobial activity aganist Gram-negative and positive bacteria as well as some fungal plant diseases .
|
-
- HY-102026
-
-
- HY-13434A
-
|
SQ23377 calcium
|
Calcium Channel
PKC
Bacterial
Apoptosis
Antibiotic
|
Infection
Cancer
|
|
Ionomycin calcium (SQ23377 calcium) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin calcium (SQ23377 calcium) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin calcium (SQ23377 calcium) also induces the activation of protein kinase C (PKC) .
|
-
- HY-135751
-
|
|
Antibiotic
DNA/RNA Synthesis
|
Infection
Cancer
|
|
Holomycin is a secondary metabolite of the dithiolopyrrolone class. Holomycin also is a broad spectrum antibiotic. Holomycin has antitumor activity and can act in vivo on RNA synthesis .
|
-
- HY-129252
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Prothracarcin is an antibiotic with antitumor activity that exerts its tumor cell toxicity by covalently binding to the C-2 amino group of guanine residues in the minor groove of DNA. Prothracarcin also shows antibacterial activity against Gram-positive bacteria and some Gram-negative bacteria such as Escherichia coli .
|
-
- HY-136457R
-
|
|
Drug Metabolite
|
Others
|
|
2-NP-AHD (Standard) is the analytical standard of 2-NP-AHD. This product is intended for research and analytical applications. 2-NP-AHD is a 2-nitrophenyl derivative of AHD (a metabolite of nitrofurans type of antibiotics), can be used as indicator of the illegal usage of nitrofuran agents .
|
-
- HY-N15029
-
|
|
Antibiotic
Bacterial
Fungal
Parasite
Adenylate Cyclase
|
Infection
|
|
Destomycin A is an aminoglycoside antibiotic with antibacterial (Gram-positive bacteria, Gram-negative bacteria), antifungal and anthelmintic activities. Destomycin A inhibits the polypeptide synthesis in cells of Escherichia coli and stimulation of adenylate cyclase in animal tissues .
|
-
- HY-108345
-
|
|
Antibiotic
|
Cancer
|
|
Bleomycin is a glycopeptide antibiotic. Bleomycin has potent antitumour activities against a range of lymphomas, head and neck cancers and germ-cell tumours. Bleomycin can be used for the research of cancer and chemotherapy .
|
-
- HY-128423R
-
|
|
Antibiotic
Bacterial
NF-κB
Apoptosis
|
Infection
Inflammation/Immunology
|
|
Tylvalosin (tartrate) (Standard) is the analytical standard of Tylvalosin (tartrate). This product is intended for research and analytical applications. Tylvalosin (Acetylisovaleryltylosin) tartrate is an orally active, broad-spectrum macrolide antibiotic with antimicrobial activity. Tylvalosin tartrate is an antiviral agent useful in studying PRRSV infection. Tylvalosin tartrate induces apoptosis. Tylvalosin tartrate also has anti-inflammatory activity, relieves oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation [4].
|
-
- HY-77641R
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Cinnamoylglycine (Standard) is the analytical standard of Cinnamoylglycine. This product is intended for research and analytical applications. Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine is used as a potential urinary biomarker indicating intact or disrupted colonization resistance during and after antibiotic treatment .
|
-
- HY-A0251R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cefpodoxime (Standard) is the analytical standard of Cefpodoxime. This product is intended for research and analytical applications. Cefpodoxime (Cefpodoxime acid) is a potent antibiotic active against gram-positive and gram-negative bacteria. Cefpodoxime inhibits the majority of cells in microbial populations. Cefpodoxime can be used for acute otitis media, sinusitis and tosillopharyngitis research .
|
-
- HY-135470R
-
|
P-7138 (Standard)
|
Antibiotic
Bacterial
|
Infection
|
|
Nifurpirinol (Standard) is the analytical standard of Nifurpirinol. This product is intended for research and analytical applications. Nifurpirinol (P-7138) is a nitroaromatic antibiotic and acts as a novel substrate for the bacterial nitroreductase (NTR) enzyme. Nifurpirinol is a more potent proagent compared to Metronidazole to trigger cell-ablation in nitroreductase expressing transgenic models[1].
|
-
- HY-B0136R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefdinir (Standard) is the analytical standard of Cefdinir. This product is intended for research and analytical applications. Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .
|
-
- HY-A0294A
-
|
MK-0826 disodium
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Ertapenem (MK-0826) disodium is a broad spectrum and long acting β-lactam antibiotic. Ertapenem disodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem disodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .
|
-
- HY-N10273
-
|
|
Fungal
|
Infection
|
|
Deoxyfusapyrone is an antifungal alpha-pyrone from Fusarium semitectum. Deoxyfusapyrone shows a strong antibiotic activity towards Geotrichum candidum in disk diffusion assays, but is not toxic to Artemia salina larvae .
|
-
- HY-B1327R
-
|
|
Bacterial
Antibiotic
Parasite
|
Infection
Inflammation/Immunology
|
|
Chlortetracycline (hydrochloride) (Standard) is the analytical standard of Chlortetracycline (hydrochloride). This product is intended for research and analytical applications. Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is a specific and potent calcium ionophore antibiotic that inhibits the binding of aminoacyl-tRNA to ribosomes.
|
-
- HY-N12201
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Funiculosin is a neutral lipophilic antibiotic that inhibits DNA and RNA viruses. Funiculosin also has antifungal activity. Funiculosin inhibits infections caused by pathogenic fungi in primary chicken embryo fibroblasts .
|
-
- HY-108402
-
|
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
|
|
Cefodizime is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime has no renal toxic effect, good tolerance and immune regulation activity, and has the potential for severe infections of the respiratory and urinary tracts .
|
-
- HY-136457S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2-NP-AHD- 13C3 is the 13C labled 2-NP-AHD (HY-136457) . 2-NP-AHD is a 2-nitrophenyl derivative of AHD (a metabolite of nitrofurans type of antibiotics), can be used as indicator of the illegal usage of nitrofuran agents .
|
-
- HY-125652
-
|
|
Antibiotic
|
Infection
|
|
Macrosphelide A is a macrolide antibiotic. Macrosphelide A inhibits growth of some ascomycetes, basidiomycetes, oomycetes and all four Gram-positive bacteria tested, including the medically important Staphylococcus aureus with a MIC of ≤500 μg/mL .
|
-
- HY-108402A
-
|
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
|
|
Cefodizime sodium is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime sodium has no renal toxic effect, good tolerance and immune regulation activity, and can be used for the research of severe infections of the respiratory and urinary tracts .
|
-
- HY-16035A
-
|
|
DNA/RNA Synthesis
Antibiotic
|
Infection
|
|
Alatrofloxacin mesylate is an antibiotic with antibacterial activity. Alatrofloxacin mesylate exhibits significant hydrophilicity in the aqueous phase, forming a very stable suspension. The degradation products of Alatrofloxacin mesylate become hydrophobic upon exposure, causing aggregation of its particles. The long-term stability of Alatrofloxacin mesylate is closely related to its polar interaction. The changes in surface tension characteristics of Alatrofloxacin mesylate particles under different lighting conditions affect their physical and chemical properties .
|
-
- HY-B0278R
-
|
Zinc bacitracin (Standard)
|
Bacterial
Antibiotic
|
Infection
|
|
Bacitracin Zinc (Standard) is the analytical standard of Bacitracin Zinc (HY-B0278). Bacitracin Zinc (Standard) is a complex formed by the binding of Bacitracin (HY-107193) with zinc ions. Bacitracin Zinc (Standard) is an orally active polypeptide antibiotic with bactericidal properties. Bacitracin Zinc (Standard) can cause DNA and deoxyribose damage, as well as improve the gut microbiota of broiler and beef cattle .
|
-
- HY-105463
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Saptomycin D is an antibiotic with antitumor activity isolated from the Streptomyces sp. HP530 strain. Saptomycin D exhibits potent inhibitory effects against Gram-positive bacteria, while demonstrating weaker inhibitory activities against certain Gram-negative bacteria and yeasts. Saptomycin D also displays remarkable antitumor properties. Saptomycin D is applicable in research within the field of oncology .
|
-
- HY-162861
-
|
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
|
3-Methyl-chuangxinmycin is an antibiotic. 3-Methyl-chuangxinmycin can affect the translation process in bacteria and mammalian cells by inhibiting the enzyme that synthesizes tryptophan tRNA (TrpRS). 3-Methyl-chuangxinmycin can downregulate genes related to interferon, TNF, and inflammatory responses in RDEB_L1 cells .
|
-
- HY-A0248
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Polymyxin B Sulfate is a potent antibacterial agent and a relatively toxic antibiotic. Polymyxin B Sulfate also is a antiendotoxin agent. Polymyxin B Sulfate shows endotoxin-neutralizing properties can be used as adjunctive research in gram-negative sepsis. Polymyxin B Sulfate shows antibacterial activities in vitro and in vivo .
|
-
- HY-P2233
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Globomycin is a lipopeptide antibiotic and a signal peptidase II (LspA) inhibitor. Globomycin inhibits processing of the prolipoprotein by binding irreversibly to the peptidase. Globomycin has toxic for the mollicute Spiroplasma melliferum with a MIC in the range 6.25-12.5 μM .
|
-
- HY-16137
-
|
Cephaloglycin
|
Bacterial
|
Infection
|
|
Cefaloglycin (Cephaloglycin) is an orally active nephrotoxic β-lactam cephalosporin antibiotic with antibacterial activity. Cefaloglycin is activity against Gram-Positive cocci other than enterococci. Cefaloglycin is toxic to mitochondrial substrate uptake and respiration .
|
-
- HY-N7449
-
-
- HY-13234R
-
|
|
Bacterial
Antibiotic
DNA/RNA Synthesis
|
Infection
Cancer
|
|
Rifaximin (Standard) is the analytical standard of Rifaximin. This product is intended for research and analytical applications. Rifaximin, a gastrointestinal-selective antibiotic, binds the β-subunit of bacterial DNA-dependent RNA polymerase, resulting in inhibition of bacterial RNA synthesis. Rifaximin susceptibility is higher against Gram-positive strains (MIC: 0.03-5 mg/ml) compared to Gram-negative bacteria (MIC: 8-50 mg/mL) .
|
-
- HY-155504
-
|
|
Beta-lactamase
Bacterial
|
Infection
|
|
Metallo-β-lactamase-IN-11 (compound 5f) is a Metallo-β-lactamases (MBLs) inhibitor, potent against bacterial metallophyllactamase CphA (IC50=45 µM). Metallo-β-lactamase-IN-11 (10 µM) inhibits NDM-1 by 49% and AIM-1 by 61%. Metallo-β-lactamase-IN-11 can be used in the research of inhibiting antibiotic resistance .
|
-
- HY-138075
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Obafluorin is a β-Lactone Antibiotic, that can be produced by Pseudomonas fluorescens ATCC 39502. Obafluorin exhibits antibacterial activity against a range of Gram-positive and Gram-negative bacteria. Obafluorin fully inhibits E. coli threonyl-tRNA synthetase .
|
-
- HY-126490
-
|
|
Bacterial
Antibiotic
DNA/RNA Synthesis
|
Infection
Cancer
|
|
Phleomycin is a copper-dependent DNA damaging agent and antibiotic with antitumor activity. Phleomycin binds to DNA and produces ROS in the presence of reducing agents (such as dithiothreitol and glutathione), inducing single-strand and double-strand breaks in DNA. Phleomycin can induce cell apoptosis or mutation and is widely used in cancer inhibition, microbial genetic transformation (as a screening marker to improve fungal transformation efficiency) and DNA repair mechanism research .
|
-
- HY-B1703
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Nifursol is a potent and orally active veterinary antibiotic for the prevention of histomoniasis. Nifursol rapidly metabolizes to form the metabolic marker 3,5-dinitrosalicyclic acid hydrazide (DNSAH) which can persist for a long time. Nifursol is widely used for the research of Escherichia Gastroenteropathy in poultry, fowl and aquatic animal .
|
-
- HY-109539
-
|
|
Antibody-Drug Conjugates (ADCs)
Apoptosis
|
Cancer
|
|
Gemtuzumab ozogamicin is an antibody-drug conjugate (ADC) consisting of a humanized immunoglobulin (IgG4) antibody directed against CD33 that is conjugated to the cytotoxic agent Calicheamicin (HY-19609). Calicheamicin is a cytotoxic antibiotic. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia (AML) .
|
-
- HY-B0518AR
-
|
|
Fungal
Antibiotic
|
Infection
|
|
Naftifine (hydrochloride) (Standard) is the analytical standard of Naftifine (hydrochloride). This product is intended for research and analytical applications. Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition .
|
-
- HY-17586
-
|
MDL-63397 hydrochloride; BI-397 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Dalbavancin hydrochloride (MDL-63397 hydrochloride) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin hydrochloride inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively .
|
-
- HY-17586A
-
|
MDL-63397; BI-397
|
Bacterial
Antibiotic
|
Infection
|
|
Dalbavancin (MDL-63397) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively .
|
-
- HY-19071
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
BK-218 is an orally active cephalosporin antibiotic that binds to penicillin-binding proteins (PBPs) and has a greater inhibitory effect than Cephalexin (HY-B0200) and Cefoxitin (HY-B1825). BK-218 has similar antibacterial activity to Cefamandole (HY-B1128) and can be used in the development of antibacterial drugs .
|
-
- HY-B1369AR
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Imipenem (Standard) is the analytical standard of Imipenem. This product is intended for research and analytical applications. Imipenem (MK0787), a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
|
-
- HY-N4117
-
|
|
Bacterial
|
Infection
|
|
Hamamelitannin, a polyphenol extracted from the bark of Hamamelis virginiana, is a quorum-sensing (QS) inhibitor. Hamamelitannin increases antibiotic susceptibility of staphylococcus aureus biofilms by affecting peptidoglycan biosynthesis and eDNA release .
|
-
- HY-N5160
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Arborcandin A is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin A exhibits IC50 values of 0.25 μg/mL and 0.05 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin A has an MIC of 4-8 μg/mL against the genus Candida .
|
-
- HY-N5165
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Arborcandin F is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin F exhibits IC50 values of 0.012 μg/mL against both Candida albicans and Aspergillus fumigatus. Additionally, Arborcandin F has an MIC of 2-4 μg/mL against the genus Candida .
|
-
- HY-B1526R
-
|
Thioacetazone (Standard); Amithiozone (Standard)
|
Bacterial
Antibiotic
|
Infection
|
|
Thiacetazone (Standard) is the analytical standard of Thiacetazone. This product is intended for research and analytical applications. Thiacetazone (Thioacetazone) is a thiourea-containing antitubercular agent and is an orally active antibiotic. Thiacetazone has antibacterial action, which inhibits growth of Mycobacterium tuberculosis H37Rv with a MIC value of 0.1 μg/mL[1].
|
-
- HY-B0479
-
|
Thiophenicol; Dextrosulphenidol
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .
|
-
- HY-13625R
-
|
L-749345 (Standard); MK-826 (Standard)
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Ertapenem sodium (Standard) is the analytical standard of Ertapenem sodium. This product is intended for research and analytical applications. Ertapenem sodium (L-749345) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem sodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem sodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract[1][2].
|
-
- HY-163331
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cresomycin is a bridged macrobicyclic antibiotic that can bind to the bacterial ribosome. Cresomycin exhibits efficacy against both Gram-positive and Gram-negative bacteria, including multidrug-resistant strains of Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa .
|
-
- HY-A0090A
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Nitrofurantoin sodium is a potent and orally active antibacterial agent. Nitrofurantoin sodium acts as an antibiotic. Nitrofurantoin sodium can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .
|
-
- HY-136943
-
|
|
Antibiotic
Parasite
Bacterial
|
Infection
|
|
K-41 is an orally active antibiotic. K-41 can be obtained from Streptomyces hygroscopicus. K-41 has antibacterial and antiplasmodial activity .
|
-
- HY-N5163
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Arborcandin D is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin D exhibits IC50 values of 3 μg/mL and 0.35 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin D has an MIC of 4 μg/mL against the genus Candida .
|
-
- HY-115349
-
|
|
Antibiotic
Bacterial
|
Infection
Neurological Disease
Cancer
|
|
Neamine tetrahydrochloride, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine tetrahydrochloride is an anti-angiogenesis agent targeting angiogenin. Neamine tetrahydrochloride has potent antibacterial, antitumor and neuroprotective activities .
|
-
- HY-N6686R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Virginiamycin M1 (Standard) is the analytical standard of Virginiamycin M1. This product is intended for research and analytical applications. Virginiamycin M1 (Pristinamycin IIA; Ostreogrycin A), produced by Streptomyces virginiae, is an polyunsaturated macrocyclic lactone antibiotic and acts as a component of Virginiamycin (HY-112665) . Virginiamycin M1 alone is against Staphylococcus aureus with a MIC of 0.25 μg/mL.
|
-
- HY-B0322S
-
|
Ro 4-2130-d4
|
Isotope-Labeled Compounds
Antibiotic
Bacterial
|
Infection
|
|
Sulfamethoxazole-d4 (Ro 4-2130-d4) is a deuterium labeled Sulfamethoxazole (HY-B0322). Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis .
|
-
- HY-118448R
-
|
|
Antibiotic
Bacterial
Fungal
Parasite
|
Infection
|
|
2,4-Diacetylphloroglucinol (Standard) is the analytical standard of 2,4-Diacetylphloroglucinol (HY-118448). This product is intended for research and analytical applications. 2,4-Diacetylphloroglucinol is a polyketide antibiotic produced by Pseudomonas fluorescens. 2,4-Diacetylphloroglucinol exhibits broad-spectrum toxicity against various organisms such as bacteria, fungi, oomycetes, and nematodes. 2,4-Diacetylphloroglucinol can also inhibit plant pathogens and affect the root development of tomato seedlings .
|
-
- HY-A0294AR
-
|
MK-0826 disodium (Standard)
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Ertapenem (disodium) (Standard) is the analytical standard of Ertapenem (disodium). This product is intended for research and analytical applications. Ertapenem (MK-0826) disodium is a broad spectrum and long acting β-lactam antibiotic. Ertapenem disodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem disodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract[1][2].
|
-
- HY-B0356B
-
|
Bay-09867 hydrochloride monohydrate
|
Topoisomerase
Apoptosis
Antibiotic
Bacterial
Mitochondrial Metabolism
Reactive Oxygen Species
|
Infection
Cancer
|
|
Ciprofloxacin (Bay-09867) hydrochloride monohydrate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin hydrochloride monohydrate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin hydrochloride monohydrate has anti-proliferative activity and induces apoptosis. Ciprofloxacin hydrochloride monohydrate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity .
|
-
- HY-121071
-
|
|
Bacterial
Nucleoside Antimetabolite/Analog
Antibiotic
|
Infection
|
|
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. Ascamycin has a selective antibacterial activity against Xanthomonas species with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL for Xanthomonas citri, Xanthomonas oryzae and Mycobacterium phlei, respectively .
|
-
- HY-N5162
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Arborcandin C is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin C exhibits IC50 values of 0.15 μg/mL and 0.015 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin C has an MIC of 1-2 μg/mL against the genus Candida .
|
-
- HY-B0395B
-
|
DU6859a monohydrate
|
Bacterial
Antibiotic
|
Infection
|
|
Sitafloxacin (DU6859a) monohydrate is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin monohydrate shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin monohydrate can be used for the research of respiratory tract infection and urinary tract infection .
|
-
- HY-N5161
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Arborcandin B is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin B exhibits IC50 values of 0.30 μg/mL and 0.025 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin B has an MIC of 2-4 μg/mL against the genus Candida .
|
-
- HY-B0356
-
-
- HY-136288
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Azide-PEG4-VC-PAB-Doxorubicin is a agent-linker conjugate composed of a cytotoxic anthracycline antibiotic Doxorubicin and a linker Azide-PEG4-VC-PAB to make antibody agent conjugate (ADC) . Azide-PEG4-VC-PAB-Doxorubicin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-B0975
-
|
Phenoxymethylpenicillin potassium salt
|
Bacterial
Antibiotic
|
Infection
|
|
Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is an orally active antibiotic. Penicillin V Potassium inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V Potassium can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis .
|
-
- HY-N5164
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Arborcandin E is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin E exhibits IC50 values of 0.1 μg/mL and 0.012 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin E has an MIC of 0.5-2 μg/mL against the genus Candida .
|
-
- HY-121544A
-
|
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
Histamine Receptor
|
Infection
|
|
Methicillin sodium hydrate is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin sodium hydrate is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins. Methicillin sodium hydrate can be used for the research of skin infections, osteomyelitis, and endocarditis .
|
-
- HY-B1252R
-
|
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
|
|
Cefalonium (Standard) is the analytical standard of Cefalonium. This product is intended for research and analytical applications. Cefalonium is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .
|
-
- HY-130838
-
|
|
Bacterial
|
Infection
|
|
JH-LPH-33, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-33 displays outstanding antibiotic activity with a MIC value of 0.66 μg/mL .
|
-
- HY-130837
-
|
|
Bacterial
|
Infection
|
|
JH-LPH-28, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-28 displays outstanding antibiotic activity with a MIC value of 0.83 μg/mL .
|
-
- HY-121544
-
|
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
Histamine Receptor
|
Infection
|
|
Methicillin is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins.Methicillin can be used for the research of skin infections, osteomyelitis, and endocarditis .
|
-
- HY-B0228S10
-
|
(R)-(-)-3-Hydroxybutanoic acid-13C2 sodium; (R)-3-Hydroxybutyric acid-13C2 sodium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
(R)-3-Hydroxybutanoic acid- 13C2 (sodium) is the 13C labeled (R)-3-Hydroxybutanoic acid (sodium) (HY-W015851). (R)-3-Hydroxybutanoic acid (sodium) is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones[1][2][3].
|
-
- HY-77036
-
Furagin
1 Publications Verification
Furazidine; Furazidin
|
Antibiotic
Bacterial
Carbonic Anhydrase
|
Infection
Cancer
|
|
Furagin (Furazidine), an analogue of Nitrofurantoin (HY-A0090), is an antibiotic with antibacterial activity against ESKAPE pathogens with MIC values of 0-32 µg/mL. Furagin inhibits human Carbonic anhydrases . Furagin is promising for research of cancer and urinary tract infections (UTIs) .
|
-
- HY-A0090
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .
|
-
- HY-19829
-
|
|
ADC Cytotoxin
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Sandramycin ia a cyclic depsipeptide antibiotic isolated from cultured broth of a Nocardioides sp. Sandramycin is also a DNA intercalator that potently binds DNA and is an ADC cytotoxin. Sandramycin is active against Gram-positive bacteria and has potent antitumor activity .
|
-
- HY-N14960
-
|
|
Antibiotic
|
|
|
Clavariopsin A is a cyclic depsipeptide antibiotic. Clavariopsin A shows antifungal activity for Candida albicans IFO 0583, Candida albicans ATCC 10231, Aspergillus niger AJ117374, Aspergillus fumigatus AJ117190, Aspergillus fumigatus JCM1739 with MIC values of 8, 8, 16, 2, 4 μg/mL, respectively .
|
-
- HY-108402R
-
|
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
|
|
Cefodizime (Standard) is the analytical standard of Cefodizime. This product is intended for research and analytical applications. Cefodizime is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime has no renal toxic effect, good tolerance and immune regulation activity, and has the potential for severe infections of the respiratory and urinary tracts .
|
-
- HY-108486
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Herbimycin A, an ansamycin antibiotic, acts as a Src family kinase inhibitor. Herbimycin A binds to the SH domain and inhibits the activity of p60 v-src and p210 BCR-ABL Herbimycin A inhibits Hsp90 and impairs recovery from heat shock. Herbimycin A exhibits antiangiogenic activity in endothelial cells in vitro.
|
-
- HY-B0356A
-
|
Bay-09867 monohydrochloride
|
Topoisomerase
Apoptosis
Antibiotic
Bacterial
Mitochondrial Metabolism
Reactive Oxygen Species
|
Infection
Cancer
|
|
Ciprofloxacin (Bay-09867) monohydrochloride is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin monohydrochloride induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin monohydrochloride has anti-proliferative activity and induces apoptosis. Ciprofloxacin monohydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity .
|
-
- HY-159687
-
|
WCK 4873
|
Antibiotic
Bacterial
|
Infection
|
|
Nafithromycin (WCK 4873) is an orally available antibiotic that inhibits community-acquired pneumonia caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Methicillin (HY-121544)-susceptible Staphylococcus aureus. The MIC90 of nafithromycin against macrolide-resistant and telithromycin (HY-A0062)-insensitive Streptococcus pneumoniae is 0.12 mg/liter .
|
-
- HY-W040298
-
|
Bay-09867 lactate
|
Topoisomerase
Apoptosis
Antibiotic
Bacterial
Mitochondrial Metabolism
Reactive Oxygen Species
|
Infection
Cancer
|
|
Ciprofloxacin (Bay-09867) lactate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin lactate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin lactate has anti-proliferative activity and induces apoptosis. Ciprofloxacin lactate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity .
|
-
- HY-D1571
-
|
|
DNA Stain
|
Others
|
|
CellTracker Blue CMF2HC Dye is a blue dye, can be used in two-channel nuclei acid sequencing, with blue and purple excitation light (450-460 nm/400-405nm or 415-450 nm/480-525nm). CellTracker Blue CMF2HC Dye can be used to rapid determination of antibiotic sensitivity of microorganisms .
|
-
- HY-118906
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
BO-1165 is an antibiotic with good antibacterial activity against Gram-negative bacteria, but almost no activity against Gram-positive bacteria and anaerobic bacteria. BO-1165 has high antibacterial activity against Pseudomonas aeruginosa (MIC50=3.12 mg/L) and P. cepacia (MIC50=1.56 mg/L) .
|
-
- HY-N0565
-
|
|
MMP
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
|
Doxycycline, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline shows antibacterial activity and anti-cancer cell proliferation activity .
|
-
- HY-W015851R
-
|
(R)-(-)-3-Hydroxybutanoic acid sodium (Standard); (R)-3-Hydroxybutyric acid sodium (Standard)
|
Endogenous Metabolite
|
Metabolic Disease
|
|
(R)-3-Hydroxybutanoic acid (sodium) (Standard) is the analytical standard of (R)-3-Hydroxybutanoic acid (sodium). This product is intended for research and analytical applications. (R)-3-Hydroxybutanoic acid ((R)-3-Hydroxybutyric acid) sodium is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones[1][2].
|
-
- HY-121348
-
|
U-47929
|
Antibiotic
Bacterial
DNA/RNA Synthesis
|
Infection
|
Ficellomycin is a nitrogen-containing bicyclic antibiotic with strong activity against Gram-positive bacteria, including multidrug-resistant strains of Staphylococcus aureus. Ficellomycin works by inducing the formation of defective 34S DNA fragments, which interfere with the semi-conservative DNA replication process. These fragments lack the ability to integrate into larger DNA segments and eventually form a complete bacterial chromosome. Ficellomycin can be used in research for various bacterial diseases .
|
-
- HY-N14107
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cinnabarin is an antibiotic which can be extracted from Polystiotus cinnabarinus, P. versicolo and Trametes cinnabarinus. Cinnabarin exhibits antibacterial activity against Gram-positive bacteria as well as antiviral activity, making it a potential candidate for infectious disease research .
|
-
- HY-129217
-
|
|
Glycosidase
|
Others
|
|
Naringinase, a hydrolytic enzymatic complex, possesses the activity of both α-L-rhamnosidase and β-D-glucosidase. Naringinase has wide occurrence in nature. Naringinase can be used in the biotransformation of steroids, antibiotics, and mainly on glycosides hydrolysis .
|
-
- HY-B0975A
-
|
Phenoxymethylpenicillin
|
Antibiotic
Bacterial
|
Infection
|
|
Penicillin V (Phenoxymethylpenicillin) is a potent and orally active antibiotic. Penicillin V shows antibacterial activity for Streptococci, Clostridium difficile and staphylococcus aureus. Penicillin V has the potential for the research of otitis, sinusitis, pharyngitis and tonsillitis .
|
-
- HY-120435
-
|
|
Bacterial
Fungal
Influenza Virus
Antibiotic
|
Infection
|
|
Tyrothricin is a polypeptide antibiotic mixture isolated from Bacillus brevis and consists of tyrocidines and gramicidins. Tyrothricin shows activity against bacteria, fungi and some viruses. Tyrothricin containing formulations are used in sore throat agents and in agents for the healing of infected superficial and small-area wounds .
|
-
- HY-B1252AS
-
|
|
Isotope-Labeled Compounds
|
Infection
|
|
Cefalonium-d4 (hydrate) is the deuterium labeled Cefalonium (hydrate)(HY-B1252A).Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .
|
-
- HY-106338
-
|
|
Bacterial
ADC Cytotoxin
Parasite
|
Infection
Cancer
|
|
Polyketomycin is a tetracyclic quinone glycoside antibiotic isolated from Streptomyces sp. or Streptomyces diastatochromogenes. Polyketomycin inhibits growth of Gram-positive bacteria, and its MIC values is less than 0.2 µg/mL. Polyketomycin has antibacterial, anticancer, antimalarial activities .
|
-
- HY-149810
-
|
|
Bacterial
Parasite
|
Infection
|
|
AcrB-IN-2 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. AcrB-IN-22 inhibits Nile Red (a known substrate of AcrB) efflux.AcrB-IN-2 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model .
|
-
- HY-110013
-
|
|
Btk
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Terreic acid, a quinone epoxide antibiotic, acts as an effective Btk inhibitor. Terreic acid blocks the interaction between PKC and the pleckstrin homology domain of Btk. Terreic acid inhibits the binding of GST-BtkPH to PKC in lysates of HMC-1 human mast cells with an IC50 of approximately 100 μM .
|
-
- HY-B1002
-
|
|
Bacterial
Antibiotic
DNA/RNA Synthesis
|
Infection
|
|
Oxolinic acid is an antibiotic against both Gram-negative and Gram-positive bacteria. Oxolinic acid can be used for the research of acute and chronic urinary tract infections. Oxolinic acid is a DNA/RNA synthesis inhibitor. Oxolinic acid acts a dopamine uptake inhibitor and stimulants locomotor effect in mice .
|
-
- HY-122534
-
|
|
Mitochondrial Metabolism
ADC Cytotoxin
Apoptosis
|
Cancer
|
|
Mensacarcin, a highly complex polyketide, strongly inhibits cell growth universally in cancer cell lines and potently induces apoptosis in melanoma cells. Mensacarcin targets to mitochondria, affects energy metabolism in mitochondria, and activates caspase-dependent apoptotic pathways. Mensacarcin, an antibiotic, can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .
|
-
- HY-B0395A
-
|
DU6859a hydrochloride
|
Antibiotic
Bacterial
|
Infection
|
|
Sitafloxacin (DU6859a) hydrochloride is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin hydrochloride shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin hydrochloride can be used for the research of respiratory tract infection and urinary tract infection .
|
-
- HY-B0536
-
|
AM-1091; CI-960; PD 127391
|
Bacterial
Antibiotic
|
Infection
|
|
Clinafloxacin (AM 1091) is a potent and broad-spectrum fluoroquinolone antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro . Clinafloxacin is against DNA gyrase and topoisomerase IV of?S. aureus with IC50 values of 0.92 μg/ml and 1.62 μg/ml, respectively .
|
-
- HY-B0479S
-
|
Thiophenicol-d3; Dextrosulphenidol-d3
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Thiamphenicol-d3 is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria)[1][2].
|
-
- HY-B0856
-
|
|
Fungal
Tyrosinase
Antibiotic
|
Infection
|
|
Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1?μg/mL . Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC50 of 72 μM . Validamycin A is a reversible tyrosinase inhibitor, with a Ki of 5.893 mM .
|
-
- HY-108402AR
-
|
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
|
|
Cefodizime (sodium) (Standard) is the analytical standard of Cefodizime (sodium). This product is intended for research and analytical applications. Cefodizime sodium is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime sodium has no renal toxic effect, good tolerance and immune regulation activity, and can be used for the research of severe infections of the respiratory and urinary tracts[1][2].
|
-
- HY-B0322A
-
|
Ro 4-2130 sodium
|
Antibiotic
Bacterial
|
Infection
|
|
Sulfamethoxazole (Ro 4-2130) sodium is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole sodium inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole sodium can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis .
|
-
- HY-B0536A
-
|
AM 1091 hydrochloride; CI 960 hydrochloride; PD127391 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Clinafloxacin hydrochloride (AM 1091 hydrochloride) is a potent and broad-spectrum fluoroquinolone antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro . Clinafloxacin hydrochloride is against DNA gyrase and topoisomerase IV of S. aureus with IC50 values of 0.92 µg/ml and 1.62 µg/ml, respectively .
|
-
- HY-N14961
-
|
|
Antibiotic
|
Infection
|
|
Clavariopsin B is a cyclic depsipeptide antibiotic. Clavariopsin B shows antifungal activity for Candida albicans IFO 0583, Candida albicans ATCC 10231, Aspergillus niger AJ117374, Aspergillus fumigatus AJ117190, Aspergillus fumigatus JCM1739 with MIC values of 8, 8, 16, 4, 4 μg/mL, respectively .
|
-
- HY-P0311
-
|
|
Bacterial
|
Infection
|
|
LAH4, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 possesses high plasmid DNA delivery capacities. LAH4 has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .
|
-
- HY-B0395
-
|
DU6859a
|
Bacterial
Antibiotic
|
Infection
|
|
Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection .
|
-
- HY-119819
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Psicofuramine a nucleoside antibiotic and has the inhibition of xanthosine 5'-phosphate aminase. Psicofuranine also specifically inhibits GMP synthase, and interrupts parasite growth. Psicofuranine exhibits a dose-dependent inhibition of P. falciparum growth .
|
-
- HY-139554
-
|
KBP-7072
|
Antibiotic
Bacterial
|
Infection
|
|
Zifanocycline (KBP-7072) is a semisynthetic third-generation aminomethylcycline antibiotic that inhibits the normal function of the bacterial ribosome. Zifanocycline exhibits a broad spectrum of in vitro antibacterial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline is available in both oral and injectable formulations. Zifanocycline can be used for the research of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections .
|
-
- HY-B1916
-
|
Spiramycin B; Spiramycin II; Foromacidin B
|
Antibiotic
Bacterial
Parasite
|
Infection
|
|
Acetylspiramycin (Spiramycin B) is an effective oral macrolide antibiotic produced by Streptomyces, It can inhibit the splenic lymphocyte transformation induced by phytohemagglutinin (PHA), LPS (HY-D1056) and antigen, reduce the procoagulant activity of macrophages, have good antibacterial effect on gram-positive bacteria, and is also an effective antigenic insect agent, which can be used to fight parasitic infection .
|
-
- HY-P0311A
-
|
|
Bacterial
|
Infection
|
|
LAH4 TFA, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 TFA possesses high plasmid DNA delivery capacities. LAH4 TFA has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .
|
-
- HY-W399940
-
|
|
Antibiotic
Influenza Virus
Drug Intermediate
|
Infection
|
|
Actiphenol is an antibiotic against coxsackievirus B3 and influenza A virus (IC50s = 14.37 and 34.4 µg/mL, respectively). Actiphenol is also an aromatic ketone that exhibits weak eukaryotic translation inhibiton activity, which is found in Streptomyces species. Actiphenol can be used as a key intermediate to synthesize Cycloheximide (HY-12320) .
|
-
- HY-B0275
-
|
|
Bacterial
HSV
Endogenous Metabolite
Antibiotic
|
Infection
|
|
Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity .
|
-
- HY-B0275A
-
|
|
Bacterial
HSV
Antibiotic
Endogenous Metabolite
|
Infection
|
|
Oxytetracycline hydrochloride is an antibiotic belonging to the tetracycline class. Oxytetracycline hydrochloride potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti-HSV-1 activity .
|
-
- HY-124508
-
-
- HY-149812
-
|
|
Bacterial
Parasite
|
Infection
|
|
Efflux pump-IN-4 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. Efflux pump-IN-4 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-4 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model .
|
-
- HY-149811
-
|
|
Bacterial
Parasite
|
Infection
|
|
Efflux pump-IN-3 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. Efflux pump-IN-3 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-3 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model .
|
-
- HY-B0356BR
-
|
|
Topoisomerase
Apoptosis
Antibiotic
Bacterial
Mitochondrial Metabolism
Reactive Oxygen Species
|
Infection
Cancer
|
|
Ciprofloxacin (hydrochloride monohydrate) (Standard) is the analytical standard of Ciprofloxacin (hydrochloride monohydrate). This product is intended for research and analytical applications. Ciprofloxacin (Bay-09867) hydrochloride monohydrate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin hydrochloride monohydrate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin hydrochloride monohydrate has anti-proliferative activity and induces apoptosis. Ciprofloxacin hydrochloride monohydrate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity .
|
-
- HY-B0356R
-
|
|
Topoisomerase
Apoptosis
Antibiotic
Bacterial
Mitochondrial Metabolism
Reactive Oxygen Species
|
Infection
Cancer
|
|
Ciprofloxacin (Standard) is the analytical standard of Ciprofloxacin. This product is intended for research and analytical applications. Ciprofloxacin (Bay-09867) is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin has anti-proliferative activity and induces apoptosis. Ciprofloxacin is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity .
|
-
- HY-N13221
-
|
|
Bacterial
Reactive Oxygen Species
Fungal
|
Cardiovascular Disease
Metabolic Disease
Cancer
|
Apple Cider Vinegar Powder is a soluble powdered form of apple cider vinegar. Apple Cider Vinegar Powder has anti-bacterial, anti-oxidant, and antibiotic properties and can help maintain the acid-base balance in the blood. Apple Cider Vinegar Powder can lower blood sugar and lipid levels. Apple Cider Vinegar Powder is used in research related to tumors, diabetes, and cardiovascular diseases .
|
-
- HY-B0027
-
|
|
Antibiotic
Bacterial
|
Infection
Metabolic Disease
|
|
Valnemulin hydrochloride is an orally effective truncated pleurotin antibiotic that inhibits protein synthesis in bacteria by binding to peptidyl transferase in the 50s ribosome subunit. Valnemulin hydrochloride effectively eliminates Mycobacterium bovis in the lungs in an experimental bovine model of Mycoplasma bovis infection. Valnemulin hydrochloride can reduce the mortality of epidemic rabbit enteropathy and has no adverse effect on the growth performance of rabbits .
|
-
- HY-106410A
-
|
DW-224a
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
|
Zabofloxacin hydrochloride (DW-224a) is a potent and seletive inhibitor of the bacterial type II and IV topoisomerases. Zabofloxacin hydrochloride has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia. Zabofloxacin hydrochloride is a novel fluoronaphthyridone quinolone that is considered as an alternative antibiotic for treatment of quinolone-susceptible (QSSP) and quinolone-resistant gonorrhea (QRSP) .
|
-
- HY-N6716
-
|
|
Fungal
Antibiotic
|
Infection
|
|
Filipin complex is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718), 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I .
|
-
- HY-N13197
-
-
- HY-P3078
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Amphomycin is a lipopeptide antibiotic that inhibits peptidoglycan synthesis and blocks cell wall development. Amphomycin exhibits potent antibacterial activities against methicillin-resistant S. aureus (MRSA), vancomycin-resistant enterococci (VRE), penicillin-gentamicin-erythromycin-resistant S. pneumonia, and linezolid-quinupristin-dalfopristin-resistant enterococci .
|
-
- HY-W142073
-
|
7-Methyltryptophan
|
Amino Acid Derivatives
|
Infection
|
|
7-Methyl-DL-tryptophan (7-Methyltryptophan) is an amino acid derivative, which is a key precursor for biosynthesis of many non-ribosomal peptide antibiotics. 7-Methyl-DL-tryptophan plays an important role in synthesis of high-efficiency antibacterial agents and analogues thereof .
|
-
- HY-125365
-
|
|
Bacterial
Reactive Oxygen Species
Antibiotic
|
Infection
|
|
Rifamycin S, a quinone, is an antibiotic against Gram-positive bacteria (including MRSA). Rifamycin S is the oxidized forms of a reversible oxidation-reduction system involving two electrons. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. Rifamycin S can be used for tuberculosis and leprosy .
|
-
- HY-B0275C
-
|
|
Bacterial
HSV
Antibiotic
Endogenous Metabolite
|
Infection
|
|
Oxytetracycline calcium is an antibiotic belonging to the tetracycline class. Oxytetracycline calcium potently inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline calcium is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline calcium also possesses anti-HSV-1 activity .
|
-
- HY-B0275B
-
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Bacterial
HSV
Antibiotic
Endogenous Metabolite
|
Infection
|
|
Oxytetracycline dihydrate is an antibiotic belonging to the tetracycline class. Oxytetracycline dihydrate potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline dihydrate is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline dihydrate also possesses anti-HSV-1 activity .
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- HY-103397
-
|
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Antibiotic
DNA Methyltransferase
Parasite
|
Infection
Cancer
|
|
Nanaomycin A is the first selective DNMT3B inhibitor with an IC50 of 500 nM. Nanaomycin A, a quinone antibiotics, reactivates silenced tumor suppressor genes in human cancer cells . Nanaomycin A inhibits in vitro growth of the human malaria parasite Plasmodium falciparum with an IC80 value of 33.1 nM .
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- HY-106410
-
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DW-224a Free base
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
|
Zabofloxacin (DW-224a Free base) is a potent and seletive inhibitor of the bacterial type II and IV topoisomerases. Zabofloxacin has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia. Zabofloxacin is a novel fluoronaphthyridone quinolone that is considered as an alternative antibiotic for treatment of quinolone-susceptible (QSSP) and quinolone-resistant gonorrhea (QRSP) .
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- HY-W013549
-
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6-APA
|
Drug Metabolite
Bacterial
|
Infection
Inflammation/Immunology
|
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6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses .
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- HY-N6796
-
|
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Antibiotic
Farnesyl Transferase
Ras
Apoptosis
Phospholipase
TNF Receptor
Atg8/LC3
|
Infection
Inflammation/Immunology
Cancer
|
|
Manumycin A is a polyketide antibiotic and an inhibitor of thioredoxin reductase 1 (TrxR-1). Manumycin A can inhibit the growth of breast cancer cells and exert its anti-tumor activity through LC3. Manumycin A can downregulate the release of pro-inflammatory cytokines in human monocytes stimulated by TNF α, and has potential anti-inflammatory activity. Manumycin A can inhibit the Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration resistant prostate cancer cells to suppress exosome biogenesis and secretion .
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-
- HY-121544AR
-
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Penicillin-binding protein (PBP)
Bacterial
Antibiotic
Histamine Receptor
|
Infection
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Methicillin (sodium hydrate) (Standard) is the analytical standard of Methicillin (sodium hydrate). This product is intended for research and analytical applications. Methicillin sodium hydrate is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin sodium hydrate is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins. Methicillin sodium hydrate can be used for the research of skin infections, osteomyelitis, and endocarditis .
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- HY-B0919
-
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CI-337; O-Diazoacetyl-L-serine; P-165
|
Bacterial
Antibiotic
DNA/RNA Synthesis
|
Infection
Cancer
|
|
Azazerine (CI-337) is a competitive inhibitor of glutamine amidotransferase. Azaserine is an antibiotic, it shows antibacterial activities. Azazerine shows anti-tumor activities and it may also act as a tumor inducer. Azazerine can be used for the research of cancer and infection .
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- HY-105284
-
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CP-70429
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Sulopenem (CP-70429) is an orally active, parenteral penem antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria. Sulopenem has the potential for urinary tract infections and intra-abdominal infections treatment. Sulopenem is inactive against Pseudomonas aeruginosa and Xanthomonas maltophilia .
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- HY-12456
-
|
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Antibiotic
ADC Cytotoxin
DNA Alkylator/Crosslinker
Necroptosis
Apoptosis
|
Cancer
|
|
Duocarmycin SA is an orally active antitumor antibiotic with an IC50 of 10 pM . Duocarmycin SA is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA. Duocarmycin SA demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells treated with proton radiation in vitro .
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- HY-W040298R
-
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Topoisomerase
Apoptosis
Antibiotic
Bacterial
Mitochondrial Metabolism
Reactive Oxygen Species
|
Infection
Cancer
|
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Ciprofloxacin (lactate) (Standard) is the analytical standard of Ciprofloxacin (lactate). This product is intended for research and analytical applications. Ciprofloxacin (Bay-09867) lactate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin lactate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin lactate has anti-proliferative activity and induces apoptosis. Ciprofloxacin lactate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity [4].
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- HY-B0356AR
-
|
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Topoisomerase
Apoptosis
Antibiotic
Bacterial
Mitochondrial Metabolism
Reactive Oxygen Species
|
Infection
Cancer
|
|
Ciprofloxacin (monohydrochloride) (Standard) is the analytical standard of Ciprofloxacin (monohydrochloride). This product is intended for research and analytical applications. Ciprofloxacin (Bay-09867) monohydrochloride is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin monohydrochloride induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin monohydrochloride has anti-proliferative activity and induces apoptosis. Ciprofloxacin monohydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity [4].
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- HY-N7112
-
|
Kitasamycin
|
Bacterial
Antibiotic
|
Infection
|
|
Leucomycin (Kitasamycin) is an orally active macrolide antibiotic produced by Streptomyces kitasatoensis. Leucomycin has broad-spectrum antibacterial activities against gram-positive and gram-negative bacteria, mycoplasma, leptospira, spirochaetes, rickettsiae and some larger viruses .
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- HY-B1906
-
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Agrept; Agrimycin; Streptomycin A
|
Antibiotic
Bacterial
|
Infection
Neurological Disease
|
|
Streptomycin (Agrept) is an effective antibiotic against M. tuberculosis, is used for the research of tuberculosis (TB). Streptomycin also is a bacteriocidal agent that can be used for the research of a number of bacterial infections. Streptomycin can bind strongly to nucleic acids, interferes and blocks protein synthesis while permitting continued RNA and DNA synthesis. Streptomycin, as a common antibiotic used in culture media, also is a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes .
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- HY-N0565A
-
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MMP
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
|
Doxycycline hydrochloride, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hydrochloride shows antibacterial activity and anti-cancer cell proliferation activity. Doxycycline hydrochloride can be used to construct gene expression regulation models .
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- HY-13858A
-
|
P-005672 hydrochloride
|
Antibiotic
Bacterial
DNA/RNA Synthesis
|
Infection
|
|
Sarecycline hydrochloride is an orally active narrow-spectrum tetracycline derivative antibiotic. Sarecycline hydrochloride has anti-inflammatory activity. Sarecycline hydrochloride inhibits the activity of Gram-positive bacteria and several types of keratobacterium acnes. Sarecycline hydrochloride interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Sarecycline hydrochloride can be used to study moderate to severe acne
.
|
-
- HY-16770
-
|
P-005672
|
Antibiotic
Bacterial
DNA/RNA Synthesis
|
Infection
|
|
Sarecycline is an orally effective narrow-spectrum tetracycline derivative antibiotic. Sarecycline has anti-inflammatory activity. Sarecycline inhibits the activity of Gram-positive bacteria and several types of keratobacterium acnes. Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Sarecycline can be used to study moderate to severe acne .
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- HY-B0536R
-
|
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Bacterial
Antibiotic
|
Infection
|
|
Clinafloxacin (Standard) is the analytical standard of Clinafloxacin. This product is intended for research and analytical applications. Clinafloxacin (AM 1091) is a potent and broad-spectrum fluoroquinolone antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro . Clinafloxacin is against DNA gyrase and topoisomerase IV of S. aureus with IC50 values of 0.92 µg/ml and 1.62 µg/ml, respectively .
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- HY-B0856R
-
|
|
Fungal
Tyrosinase
Antibiotic
|
Infection
|
|
Validamycin A (Standard) is the analytical standard of Validamycin A. This product is intended for research and analytical applications. Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1 μg/mL . Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC50 of 72 μM . Validamycin A is a reversible tyrosinase inhibitor, with a Ki of 5.893 mM .
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- HY-15597
-
|
Procoxacin
|
Bacterial
Wnt
β-catenin
Mitophagy
Autophagy
Apoptosis
Antibiotic
Parasite
|
Cancer
|
|
Salinomycin (Procoxacin), a polyether potassium ionophore antibiotic, selectively inhibits the growth of gram-positive bacteria. Salinomycin is a potent inhibitor of Wnt/β-catenin signaling, blocks Wnt-induced LRP6 phosphorylation. Salinomycin shows selective activity against human cancer stem cells .
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- HY-A0090R
-
|
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Bacterial
Antibiotic
|
Infection
|
|
Nitrofurantoin (Standard) is the analytical standard of Nitrofurantoin. This product is intended for research and analytical applications. Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .
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- HY-B0975R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Penicillin V (Potassium) (Standard) is the analytical standard of Penicillin V (Potassium). This product is intended for research and analytical applications. Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is an orally active antibiotic. Penicillin V Potassium inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V Potassium can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis .
|
-
- HY-162836
-
|
4-O-(Carboxymethyl)-Rifamycin
|
Antibiotic
Bacterial
|
Infection
|
|
Rifamycin B (4-O-(Carboxymethyl)-Rifamycin) is a member of ansamycin antibiotics family with an anti-mycobacterial activity against tuberculosis, leprosy and AIDS-related mycobacterial infections. Rifamycin B is a metabolic product of Nocardia inediterranei, which can yield Rifamycin O and Rifamycin S (HY-125365) by microbial transformation .
|
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- HY-130004
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
MsbA-IN-6 is a potent inhibitor of MsbA. MsbA-IN-6 is an antibiotic. Gram-negative ATP-binding cassette (ABC) transporter MsbA, an essential inner membrane protein, transports lipopolysaccharide from the inner leaflet to the periplasmic face of the inner membrane. MsbA-IN-6 kills Escherichia coli through inhibition of its ATPase and transport activity, with no loss of activity against clinical multidrug-resistant strains .
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-
- HY-B0275AR
-
|
|
Bacterial
HSV
Antibiotic
Endogenous Metabolite
|
Infection
|
|
Oxytetracycline (hydrochloride) (Standard) is the analytical standard of Oxytetracycline (hydrochloride). This product is intended for research and analytical applications. Oxytetracycline hydrochloride is an antibiotic belonging to the tetracycline class. Oxytetracycline hydrochloride potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti-HSV-1 activity .
|
-
- HY-147349
-
|
|
Beta-lactamase
Bacterial
|
Infection
|
|
ANT3310 sodium is a broad-spectrum covalent Serine β-Lactamase inhibitor, with IC50 values ranging from 1 nM to 175 nM (a panel of Serine β-Lactamase). ANT3310 sodium potentiates activity of β-lactam antibiotics against Carbapenem-Resistant Enterobacterales (CRE) and Acinetobacter baumannii (CRAB). ANT3310 sodium can be used in the research of bacterial infection .
|
-
- HY-P10556
-
|
|
Bacterial
|
Infection
|
|
(KFF)3K is a cell penetrating peptide that can promote the absorption of other antibiotics by disrupting the outer membrane of bacteria. (KFF)3K can be introduced into a hydrocarbon scaffold to induce its antibacterial properties, making it an effective antimicrobial peptide. (KFF)3K can be used in the development of new antimicrobial agents .
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-
- HY-B0275R
-
|
|
Bacterial
HSV
Endogenous Metabolite
Antibiotic
|
Infection
|
|
Oxytetracycline (Standard) is the analytical standard of Oxytetracycline. This product is intended for research and analytical applications. Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity .
|
-
- HY-N0565R
-
|
|
MMP
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
|
Doxycycline (Standard) is the analytical standard of Doxycycline. This product is intended for research and analytical applications. Doxycycline, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline shows antibacterial activity and anti-cancer cell proliferation activity [4] .
|
-
- HY-N0565B
-
|
Doxycycline hydrochloride hemiethanolate hemihydrate; WC2031
|
Antibiotic
MMP
Bacterial
Parasite
|
Infection
Cancer
|
|
Doxycycline hyclate, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor. Doxycycline hyclate shows antibacterial activity and anti-cancer cell proliferation activity. Doxycycline hyclate can be used to construct gene expression regulation models .
|
-
- HY-N0565AR
-
|
|
MMP
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
|
Doxycycline (hydrochloride) (Standard) is the analytical standard of Doxycycline (hydrochloride). This product is intended for research and analytical applications. Doxycycline hydrochloride, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hydrochloride shows antibacterial activity and anti-cancer cell proliferation activity [4] .
|
-
- HY-B0975AR
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Penicillin V (Standard) is the analytical standard of Penicillin V. This product is intended for research and analytical applications. Penicillin V (Phenoxymethylpenicillin) is a potent and orally active antibiotic. Penicillin V shows antibacterial activity for Streptococci, Clostridium difficile and staphylococcus aureus. Penicillin V has the potential for the research of otitis, sinusitis, pharyngitis and tonsillitis [4].
|
-
- HY-B1374S1
-
|
(-)-Florfenicol-d3; SCH-25298-d3
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Florfenicol-d3 is the deuterium labeled Florfenicol. Florfenicol, a commonly used veterinary antibiotic, is currently indicated for bovine respiratory disease, and also used in aquaculture for the control of enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g.
|
-
- HY-B1831
-
|
LY 333328; Orbactiv
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
|
|
Oritavancin (LY 333328), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .
|
-
- HY-N0565C
-
|
|
MMP
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
|
Doxycycline calcium, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline calcium shows antibacterial activity and anti-cancer cell proliferation activity. Doxycycline calcium can be used to construct gene expression regulation models .
|
-
- HY-B0322AR
-
|
Ro 4-2130 sodium (Standard)
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Sulfamethoxazole (Standard) (Ro 4-2130 (Standard)) sodium is the analytical standard of Sulfamethoxazole sodium (HY-B0322A). This product is intended for research and analytical applications. Sulfamethoxazole (Ro 4-2130) sodium is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole sodium inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole sodium can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis.
|
-
- HY-130838R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
JH-LPH-33 (Standard) is the analytical standard of JH-LPH-33. This product is intended for research and analytical applications. JH-LPH-33, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-33 displays outstanding antibiotic activity with a MIC value of 0.66 μg/mL[1].
|
-
- HY-130837R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
JH-LPH-28 (Standard) is the analytical standard of JH-LPH-28. This product is intended for research and analytical applications. JH-LPH-28, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-28 displays outstanding antibiotic activity with a MIC value of 0.83 μg/mL[1].
|
-
- HY-B1286
-
|
Sodium piperacillin
|
Bacterial
Antibiotic
Penicillin-binding protein (PBP)
|
Infection
Cancer
|
|
Piperacillin sodium is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .
|
-
- HY-B1257
-
|
Sodium cefmetazole
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .
|
-
- HY-B1595
-
|
CS 1170
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Cefmetazole (CS 1170) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative and anaerobic bacteria. Cefmetazole binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .
|
-
- HY-B0479S1
-
|
Thiophenicol-d3-1; Dextrosulphenidol-d3-1
|
Isotope-Labeled Compounds
|
Infection
|
|
Thiamphenicol-d3-1 (Thiophenicol-d3-1; Dextrosulphenidol-d3-1) is the deuterium-labeled Thiamphenicol (HY-B0479) . Thiamphenicol (Thiophenicol)，a methyl-sulfonyl derivative of Chloramphenicol，is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit，leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative，Gram-positive aerobic and anaerobic bacteria) .
|
-
- HY-B0322S1
-
|
Ro 4-2130-13C6
|
Isotope-Labeled Compounds
Antibiotic
Bacterial
|
Infection
|
|
Sulfamethoxazole- 13C6 (Ro 4-2130- 13C6) is a 13C labeled Sulfamethoxazole (HY-B0322). Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis .
|
-
- HY-N125722
-
|
Aabomycin A1
|
ATP Synthase
Antibiotic
|
Infection
|
|
Venturicidin A (Aabomycin A1), from actinomycetes, is a membrane-active natural product inhibitor of ATP synthase. Venturicidin A potentiates the aminoglycoside antibiotic gentamicin against multidrug-resistant clinical isolates of Staphylococcus, Enterococcus, and Pseudomonas aeruginosa. Venturicidin A shows noticeable toxicity toward human embryonic-kidney (HEK)cells with an IC50 of 31 μg/mL.
|
-
- HY-118448
-
|
|
Antibiotic
Bacterial
Fungal
Parasite
|
Infection
|
|
2,4-Diacetylphloroglucinol is a polyketide antibiotic produced by Pseudomonas fluorescens. 2,4-Diacetylphloroglucinol exhibits broad-spectrum toxicity against various organisms such as bacteria, fungi, oomycetes, and nematodes. 2,4-Diacetylphloroglucinol can also inhibit plant pathogens and affect the root development of tomato seedlings .
|
-
- HY-W062216
-
|
|
Bacterial
Arginase
|
Infection
|
|
2-Aminoimidazole is a potent antibiofilm agent that can be used as an adjuvant to antimicrobial. 2-aminoimidazoles disrupts the ability of bacteria to protect themselves by inhibiting biofilm formation and genetically-encoded antibiotic resistance traits. 2-Aminoimidazole is also a weak noncompetitive inhibitor of human arginase I with a Ki of 3.6 mM .
|
-
- HY-151944
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Antibacterial agent 128 is a siderophore analog-Ciprofloxacin (Ciprofloxacin (HY-B0356)) conjugate with a cleavable linker. Antibacterial agent 128 shows antibiotic activities against P. aeruginosa (MIC values of 0.25-64 μg/mL) and B. pseudomallei (MIC values of 1-32 μg/mL) .
|
-
- HY-B1906R
-
|
|
Antibiotic
Bacterial
|
Infection
Neurological Disease
|
|
Streptomycin (Standard) is the analytical standard of Streptomycin. This product is intended for research and analytical applications. Streptomycin (Agrept) is an effective antibiotic against M. tuberculosis, is used for the research of tuberculosis (TB). Streptomycin also is a bacteriocidal agent that can be used for the research of a number of bacterial infections. Streptomycin can bind strongly to nucleic acids, interferes and blocks protein synthesis while permitting continued RNA and DNA synthesis. Streptomycin, as a common antibiotic used in culture media, also is a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes .
|
-
- HY-B1831A
-
|
LY333328 diphosphate
|
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Oritavancin diphosphate (LY333328 diphosphate), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin diphosphate shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin diphosphate inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin diphosphate inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin diphosphate enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .
|
-
- HY-N0565BR
-
|
|
Antibiotic
MMP
Bacterial
Parasite
|
Infection
Cancer
|
|
Doxycycline hyclate (Standard) is the analytical standard of Doxycycline hyclate. This product is intended for research and analytical applications. Doxycycline hyclate, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hyclate shows antibacterial activity and anti-cancer cell proliferation activity .
|
-
- HY-B0275BR
-
|
|
Bacterial
HSV
Antibiotic
Endogenous Metabolite
|
Infection
|
|
Oxytetracycline (dihydrate) (Standard) is the analytical standard of Oxytetracycline (dihydrate). This product is intended for research and analytical applications. Oxytetracycline dihydrate is an antibiotic belonging to the tetracycline class. Oxytetracycline dihydrate potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline dihydrate is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline dihydrate also possesses anti-HSV-1 activity .
|
-
- HY-125365R
-
|
|
Bacterial
Reactive Oxygen Species
Antibiotic
|
Infection
|
|
Rifamycin S (Standard) is the analytical standard of Rifamycin S. This product is intended for research and analytical applications. Rifamycin S, a quinone, is an antibiotic against Gram-positive bacteria (including MRSA). Rifamycin S is the oxidized forms of a reversible oxidation-reduction system involving two electrons. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. Rifamycin S can be used for tuberculosis and leprosy .
|
-
- HY-W013549R
-
|
|
Drug Metabolite
Bacterial
|
Infection
|
|
6-Aminopenicillanic acid (Standard) is the analytical standard of 6-Aminopenicillanic acid. This product is intended for research and analytical applications. 6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses .
|
-
- HY-103397R
-
|
|
Antibiotic
DNA Methyltransferase
Parasite
|
Infection
Cancer
|
|
Nanaomycin A (Standard) is the analytical standard of Nanaomycin A. This product is intended for research and analytical applications. Nanaomycin A is the first selective DNMT3B inhibitor with an IC50 of 500 nM. Nanaomycin A, a quinone antibiotics, reactivates silenced tumor suppressor genes in human cancer cells[1]. Nanaomycin A inhibits in vitro growth of the human malaria parasite Plasmodium falciparum with an IC80 value of 33.1 nM[2].
|
-
- HY-P1649B
-
|
NAB741 acetate
|
Bacterial
Antibiotic
|
Infection
|
|
SPR741 acetate (NAB741 acetate) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 acetate increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 acetate inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 acetate .
|
-
- HY-N6693
-
|
NSC 122023
|
Apoptosis
Antibiotic
Autophagy
Fungal
|
Infection
Others
Cancer
|
|
Valinomycin is a potassium-specific ionophore, the valinomycin-K + complex can be incorporated into biological bilayer membranes with the hydrophobic surface of valinomycin, destroys the normal K + gradient across the membrane, and as a result kills the cells, incorporating into liposomes can significantly reduces the cytotoxicity and enhances the targeting effect. Valinomycin exhibits antibiotic, antifungal, antiviral, antitumor and insecticidal efficacy, thus can be used for relevant research .
|
-
- HY-P1649
-
|
NAB741
|
Bacterial
Antibiotic
|
Infection
|
|
SPR741 (NAB741) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 .
|
-
- HY-17560
-
-
- HY-13858AR
-
|
|
Antibiotic
Bacterial
DNA/RNA Synthesis
|
Infection
|
|
Sarecycline (hydrochloride) (Standard) is the analytical standard of Sarecycline (hydrochloride). This product is intended for research and analytical applications. Sarecycline hydrochloride is an orally active narrow-spectrum tetracycline derivative antibiotic. Sarecycline hydrochloride has anti-inflammatory activity. Sarecycline hydrochloride inhibits the activity of Gram-positive bacteria and several types of keratobacterium acnes. Sarecycline hydrochloride interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Sarecycline hydrochloride can be used to study moderate to severe acne .
|
-
- HY-118230
-
|
Rubiflavin B
|
Antibiotic
|
Infection
|
|
Kidamycin is a polymycin antibiotic that can be extracted from the antitumor antibiotic rubraflavin .
|
-
- HY-15142
-
|
Hydroxydaunorubicin hydrochloride; ADR
|
Topoisomerase
ADC Cytotoxin
AMPK
Autophagy
Apoptosis
HIV
HBV
Mitophagy
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Doxorubicin hydrochloride (Hydroxydaunorubicin hydrochloride; ADR), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy .
|
-
- HY-15597R
-
|
Procoxacin (Standard)
|
Bacterial
Wnt
β-catenin
Mitophagy
Autophagy
Apoptosis
Antibiotic
Parasite
|
Cancer
|
|
Salinomycin (Standard) is the analytical standard of Salinomycin. This product is intended for research and analytical applications. Salinomycin (Procoxacin), a polyether potassium ionophore antibiotic, selectively inhibits the growth of gram-positive bacteria. Salinomycin is a potent inhibitor of Wnt/β-catenin signaling, blocks Wnt-induced LRP6 phosphorylation. Salinomycin shows selective activity against human cancer stem cells[1][2][3].
|
-
- HY-B0519B
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Tylosin phosphate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .
|
-
- HY-B1923A
-
|
Pipracil hydrate
|
Antibiotic
Bacterial
Beta-lactamase
Penicillin-binding protein (PBP)
|
Infection
Cancer
|
|
Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin hydrate is most commonly used in combination with the β-lactamase inhibitor Tazobactam (HY-B1418) .
|
-
- HY-B0519A
-
Tylosin
1 Publications Verification
|
Bacterial
Antibiotic
|
Infection
|
|
Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .
|
-
- HY-B1831AR
-
|
|
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Oritavancin (diphosphate) (Standard) is the analytical standard of Oritavancin (diphosphate). Oritavancin diphosphate (Standard), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin diphosphate (Standard) shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin diphosphate (Standard) inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin diphosphate (Standard) inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin diphosphate (Standard) enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .
|
-
- HY-P1649A
-
|
NAB741 TFA
|
Bacterial
Antibiotic
|
Infection
|
|
SPR741 TFA (NAB741 TFA) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 TFA increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 TFA inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 TFA .
|
-
- HY-B0398
-
|
|
Bacterial
Antibiotic
Topoisomerase
|
Infection
|
|
Nalidixic acid, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria .
|
-
- HY-113678
-
|
Polymyxin E
|
Antibiotic
Bacterial
|
Infection
|
|
Colistin (Polymyxin E) is an orally active polypeptide antibiotic. Colistin has excellent activity against various Gram-negative rod-shaped bacteria, including multidrug-resistant Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae. Colistin is associated with nephrotoxicity. Colistin can be used for the research of infections caused by Gram-negative bacilli .
|
-
- HY-121333
-
|
|
Antibiotic
Wnt
β-catenin
|
Infection
Neurological Disease
Cancer
|
|
Dinactin, an antibiotic ionophore produced by Streptomyces species, as an effective small molecule targeting Wnt/β-catenin signaling pathway in cancer cells. Dinactin shows marked inhibition of HCT-116 cell growth with an IC50 of 1.1 µM. Dinactin shows anti-proliferative activity against the cancer cells in apoptosis-independent manner. Dinactin is also an effective agent for the research of neuropathic pain .
|
-
- HY-B1286R
-
|
|
Bacterial
Antibiotic
Penicillin-binding protein (PBP)
|
Infection
|
|
Piperacillin (sodium) (Standard) is the analytical standard of Piperacillin (sodium). This product is intended for research and analytical applications. Piperacillin sodium is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .
|
-
- HY-B0519
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .
|
-
- HY-B0398A
-
|
|
Bacterial
Antibiotic
Topoisomerase
|
Infection
|
|
Nalidixic acid sodium salt, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria .
|
-
- HY-B1257R
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Cefmetazole (sodium) (Standard) is the analytical standard of Cefmetazole (sodium). This product is intended for research and analytical applications. Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .
|
-
- HY-130224
-
|
|
Antibiotic
|
Infection
|
|
Altromycin C is a pluramycin-like antibiotic with antibacterial activity. Altromycin C is related to pluramycin-type antibiotics but is structurally distinct. The biological activity of Altromycin C makes it an antibiotic complex worthy of attention .
|
-
- HY-113700
-
|
|
Antibiotic
|
Cancer
|
|
PD 116779 is an Antibiotic with anticancer activity. PD 116779 demonstrates moderate cytotoxicity against L1210 lymphocytic leukemia and HCT-8 human colon adenocarcinoma cell lines with IC50 values of 3.55x10 -7 and 4.08x10 -7 M, respectively .
|
-
- HY-B1923
-
|
Pipracil
|
Antibiotic
Bacterial
Beta-lactamase
Penicillin-binding protein (PBP)
|
Infection
Cancer
|
|
Piperacillin is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .
|
-
- HY-18324
-
|
REP-3123
|
Antibiotic
|
Inflammation/Immunology
|
|
CRS3123 is a potent and orally active narrow-spectrum antibiotic. CRS3123 inhibits bacterial methionyl-tRNA synthetase. CRS3123 has potent activity against Clostridium difficile (C. difficile) and aerobic Gram-positive bacteria but little activity against Gram-negative bacteria, including anaerobes. CRS3123 has the potential for the research of C. difficile infections .
|
-
- HY-P2302
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Defensin HNP-3 human is a cytotoxic antibiotic peptide known as "defensin". Defensin HNP-3 human has inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Defensin HNP-3 human is initially synthesized as the 94 amino acids preproHNP(1-94), which is hydrolyzed to proHNP(20-94) and converted to mature HNP(65-94) after the removal of anion precursors .
|
-
- HY-114979
-
|
|
Antibiotic
Fungal
Apoptosis
|
Infection
Cancer
|
|
Pyoluteorin is an antibiotic that inhibits Oomycete fungi, including the plant pathogen Pythium ultimum, and suppresses plant diseases caused by this fungus . Pyoluteorin induces human triple-negative breast cancer MDA-MB-231 cells apoptosis in vitro. Pyoluteorin can be used for the research of human triple-negative breast cancer .
|
-
- HY-B1118
-
|
RP-14539; PM-185184
|
Parasite
Antibiotic
Bacterial
|
Infection
|
|
Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .
|
-
- HY-B1118A
-
|
RP-14539 hemihydrate; PM-185184 hemihydrate
|
Antibiotic
Bacterial
Parasite
|
Infection
|
|
Secnidazole (RP-14539) hemihydrate is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole hemihydrate, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole hemihydrate has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole hemihydrate can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .
|
-
- HY-P1674A
-
|
POL7080 TFA
|
Bacterial
Antibiotic
|
Infection
|
|
Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with MIC50 and MIC90 values both of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance .
|
-
- HY-113604
-
|
|
TGF-β Receptor
|
Cancer
|
Pentabromopseudilin (PBrP) is a marine antibiotic isolated from the marine bacteria Pseudomonas bromoutilis and Alteromonas luteoviolaceus. PBrP exhibits antimicrobial, anti-tumour and phytotoxic activities. PBrP is a reversible and allosteric inhibitor of myosin Va (MyoVa). PBrP also is a potent inhibitor of transforming growth factor-β (TGF-β) activity. PBrP can be used for the research of fibrotic diseases and cancer .
|
-
- HY-P1674
-
|
POL7080
|
Bacterial
Antibiotic
|
Infection
|
|
Murepavadin (POL7080), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with both MIC50 and MIC90 values of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance .
|
-
- HY-103251R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cefalonium (dihydrate) (Standard) is the analytical standard of Cefalonium (dihydrate). This product is intended for research and analytical applications. Cefalonium dihydrate is a cephalosporin antibiotic. Cefalonium (dihydrate) is effective against Staphylococcus aureus. Cefalonium (dihydrate) has anti-inflammatory and antibacterial activities .
|
-
- HY-126629
-
|
|
Bacterial
|
Infection
|
|
Antibacterial agent 12, a biaryloxazolidinone analogue, is an antibacterial agent against antibiotic-susceptible and antibiotic-resistant Gram-positive bacteria .
|
-
- HY-125745
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Loloatin B 10 is an antibiotic, which exhibits antibacterial efficacy against gram positive antibiotic resistant human pathogens .
|
-
- HY-15142A
-
|
Hydroxydaunorubicin
|
ADC Cytotoxin
Antibiotic
Bacterial
Topoisomerase
AMPK
HIV
Autophagy
Mitophagy
Apoptosis
HBV
|
Infection
Cancer
|
|
Doxorubicin (Hydroxydaunorubicin), a broad-spectrum anthracycline antibiotic with cytotoxic properties, is an anti-cancer chemotherapy agent. Doxorubicin has fluorescence properties. Doxorubicin inhibits topoisomerase II with an IC50 of 2.67 μM, thus stopping DNA replication. Doxorubicin reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin induces apoptosis and autophagy . Doxorubicin inhibits human DNA topoisomerase I with an IC50 of 0.8 μM .
|
-
- HY-A0098
-
|
|
Bacterial
Fungal
Influenza Virus
Antibiotic
|
Infection
Inflammation/Immunology
Cancer
|
|
Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity .Tunicamycin increases exosome release in cervical cancer cells .
|
-
- HY-15142R
-
|
|
Topoisomerase
ADC Cytotoxin
AMPK
Autophagy
Apoptosis
HIV
HBV
Mitophagy
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Doxorubicin hydrochloride (Standard) is the analytical standard of Doxorubicin hydrochloride. This product is intended for research and analytical applications. Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy .
|
-
- HY-B0519AR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Tylosin (Standard) is the analytical standard of Tylosin. This product is intended for research and analytical applications. Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .
|
-
- HY-B0519BR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Tylosin (phosphate) (Standard) is the analytical standard of Tylosin (phosphate). This product is intended for research and analytical applications. Tylosin phosphate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .
|
-
- HY-P99551
-
|
KBSA301; AR-301
|
Antibiotic
|
Infection
|
|
Tosatoxumab (AR-301; KBSA301) is a human immunoglobulin G1 monoclonal antibody that specifically neutralizes alpha-toxin (alpha-hemolysin; Hla) of S. aureus. Tosatoxumab binds to an N-terminal epitope of alpha-toxin, thereby preventing functional toxin pore oligomerisation. Tosatoxumab has the potential for passive immunotherapy in the S. aureus pneumonia as an adjunctive therapy to standard antibiotic agent .
|
-
- HY-N13869
-
-
- HY-B0198A
-
-
- HY-B0198
-
-
- HY-110271
-
|
|
Antibiotic
|
Others
|
|
N-Acetylpuromycin is a inactive form of the antibiotic puromycin. N-Acetylpuromycin is the last intermediate of the puromycin antibiotic biosynthetic pathway in Streptomyces alboniger .
|
-
- HY-120383
-
|
Sacromycin; U-4761
|
Antibiotic
Bacterial
|
Infection
|
|
Amicetin is a potent antibiotic. Amicetin shows antibiotic activities against gram-positive bacteria. Amicetin inhibits protein synthesis .
|
-
- HY-B1381A
-
|
FR-17027 trihydrate; FK-027 trihydrate; CL-284635 trihydrate
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
Cancer
|
|
Cefixime trihydrate (FR-17027 trihydrate) is an antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections .
|
-
- HY-B1381
-
|
FR-17027; FK-027; CL-284635
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Cefixime (FR-17027) is an orally active antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections .
|
-
- HY-B1118R
-
|
|
Parasite
Antibiotic
Bacterial
|
Infection
|
|
Secnidazole (Standard) is the analytical standard of Secnidazole. This product is intended for research and analytical applications. Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .
|
-
- HY-B0398R
-
|
|
Bacterial
Antibiotic
Topoisomerase
|
Infection
|
|
Nalidixic acid (Standard) is the analytical standard of Nalidixic acid. This product is intended for research and analytical applications. Nalidixic acid, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria .
|
-
- HY-B0519R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Tylosin (tartrate) (Standard) is the analytical standard of Tylosin (tartrate). This product is intended for research and analytical applications. Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .
|
-
- HY-B1923R
-
|
|
Bacterial
Antibiotic
Beta-lactamase
Penicillin-binding protein (PBP)
|
Infection
Cancer
|
|
Piperacillin (Standard) is the analytical standard of Piperacillin. This product is intended for research and analytical applications. Piperacillin is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .
|
-
- HY-133704
-
|
|
Bacterial
Fungal
Antibiotic
|
Infection
|
|
Pyrrolnitrin is an antibiotic isolated from Pseudomonas pyrrocinia. Pyrrolnitrin shows a broad spectrum of antibiotic activity against fungi, yeast and gram-positive bacteria .
|
-
- HY-N14797
-
-
- HY-101593
-
-
- HY-100577
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Ticarcillin sodium is an injectable antibiotic for the treatment of Gram-negative bacteria, particularly Pseudomonas aeruginosa. It is also one of the few antibiotics capable of treating Stenotrophomonas maltophilia infections .
|
-
- HY-N0113BR
-
|
Ordenina hydrochloride (Standard); Peyocactine hydrochloride (Standard)
|
Antibiotic
|
Infection
|
|
Hordenine (hydrochloride) (Standard) is the analytical standard of Hordenine (hydrochloride). This product is intended for research and analytical applications. Hordenine (hydrochloride), an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production[1].
|
-
- HY-N0113B
-
|
Ordenina hydrochloride; Peyocactine hydrochloride
|
Antibiotic
|
Infection
|
|
Hordenine (hydrochloride), an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .
|
-
- HY-163190
-
|
|
Bacterial
|
Infection
|
|
NDM-1 inhibitor-4 (compound 27) is a NDM-1 inhibitor with Ki of 1.7 μM. NDM-1 inhibitor-4 has antimicrobial effect .
|
-
- HY-A0170
-
|
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
|
Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1 .
|
-
- HY-B0712A
-
|
Ro 13-9904 sodium hydrate
|
Bacterial
Antibiotic
GSK-3
Aurora Kinase
|
Infection
Cancer
|
|
Ceftriaxone sodium hydrate (Ro 13-9904 sodium hydrate) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone sodium hydrate is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone sodium hydrate is an inhibitor of Aurora B. Ceftriaxone sodium hydrate has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone sodium hydrate can be used in the study of bacterial infections and meningitis .
|
-
- HY-B0712
-
|
Ro 13-9904 free acid
|
Bacterial
Antibiotic
GSK-3
Aurora Kinase
|
Infection
Inflammation/Immunology
Cancer
|
|
Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .
|
-
- HY-103399
-
|
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
|
Trovafloxacin mesylate is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin mesylate blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin mesylate is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin mesylate does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin mesylate leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1 .
|
-
- HY-N14600
-
-
- HY-N14798
-
-
- HY-N14888
-
-
- HY-N14836
-
-
- HY-U00154
-
-
- HY-B0198R
-
-
- HY-N12257
-
|
|
Fungal
Cytochrome P450
|
Infection
|
|
Antimycin A2 is the component of the antibiotic antimycin A. Antimycin A is an antibiotic, that exhibits inhibitory activity against fungi and some insects through inhibition of respiration and cytochrome b reoxidation .
|
-
- HY-106257A
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Ceftolozane TFA is a cephalosporin antibiotic that can be used to inhibit Gram-negative bacterial infections. Ceftolozane TFA can be used to synthesize new antibiotic that are more potent and safer .
|
-
- HY-105099
-
|
KRM-1648; ABI-1648
|
Antibiotic
DNA/RNA Synthesis
Bacterial
|
Infection
Inflammation/Immunology
|
|
Rifalazil (KRM-1648; ABI-1648), a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase . Rifalazil (KRM-1648; ABI-1648) is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis with MIC values from 0.00025 to 0.0025 μg/ml . Rifalazil (KRM-1648; ABI-1648) has the potential for the treatment of Chlamydia infection, Clostridium difficile associated diarrhea (CDAD), and tuberculosis (TB) .
|
-
- HY-W764182
-
|
|
Antibiotic
|
Infection
|
|
Cephalosporinase, bacillus are enzymes produced by bacillus, inactivated and degrade the ability of the cephalosporin class of antibiotics. Cephalosporins are a class of β-lactam antibiotics that are widely used to treat bacterial infections .
|
-
- HY-B0198AR
-
|
|
Antibiotic
Bacterial
Penicillin-binding protein (PBP)
5-HT Receptor
|
Infection
Neurological Disease
Inflammation/Immunology
|
|
Cefaclor (monohydrate) (Standard) is the analytical standard of Cefaclor (monohydrate). This product is intended for research and analytical applications. Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3). Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections .
|
-
- HY-N15037
-
-
- HY-129475
-
-
- HY-B0671
-
-
- HY-125682
-
-
- HY-N12089
-
-
- HY-122384
-
-
- HY-17028
-
-
- HY-101818
-
-
- HY-125561
-
-
- HY-N15395
-
-
- HY-N8381
-
-
- HY-126866
-
|
|
Bacterial
|
Infection
|
|
Lankacidin C 8-acetate is an antibiotic with antibacterial activity. Lankacidin C 8-acetate, as a component of the Lankacidin group (T-2636) antibiotics, shows inhibitory effects against specific bacteria. Lankacidin C 8-acetate can generate other esterates by reacting with different acyl donors, indicating its importance in the synthesis of antibiotics .
|
-
- HY-B0712B
-
|
Ro 13-9904
|
Antibiotic
GSK-3
Bacterial
Aurora Kinase
|
Infection
Inflammation/Immunology
Cancer
|
|
Ceftriaxone sodium salt (Ro 13-9904) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone sodium salt is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone sodium salt is an inhibitor of Aurora B. Ceftriaxone sodium salt has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone sodium salt can be used in the study of bacterial infections and meningitis .
|
-
- HY-121222
-
|
|
PI3K
Apoptosis
|
Cancer
|
|
alpha-Bisabolol, an orally active sesquiterpene alcohol, induces cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol exerts a protective action against Cisplatin (HY-17394)-induced nephrotoxicity by mitigating inflammation and oxidative stress through the inhibition of NFκB activation. alpha-Bisabolol exhibits anti-inflammatory, analgesic, antibiotic and anticancer activities .
|
-
- HY-A0062
-
|
HMR3647; RU66647
|
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Telithromycin (HMR3647) is a novel ketolide antibiotic that structurally resembles macrolides. Telithromycin belongs to the ketolide family that is characterized by a keto group at position 3 of the macrolide ring and is active against bacteria causing community-acquired pneumonia, acute exacerbation of chronic bronchitis, and acute sinusitis. Telithromycin also has similar immunomodulatory effects as macrolides. Telithromycin can be used for the research of respiratory infections including bronchial asthma .
|
-
- HY-N6769
-
|
Monorden
|
HSP
Bacterial
Antibiotic
Parasite
|
Infection
|
|
Radicicol is an inhibitor of Hsp90 with an IC50 value < 1 μM, and leads to proteasomal degradation . Radicicol exhibits inhibition on PDK with IC50s of 230 μM (PDK1) and 400 μM (PDK3). Radicicol is an antifungal and antimalarial antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB . Radicicol is also an inhibitor of fat mass and obesity-associated protein (FTO), with an IC50 value of 16.04 μM .
|
-
- HY-B0712AR
-
|
|
Bacterial
Antibiotic
GSK-3
Aurora Kinase
|
Infection
Cancer
|
|
Ceftriaxone (sodium hydrate) (Standard) is the analytical standard of Ceftriaxone (sodium hydrate). This product is intended for research and analytical applications. Ceftriaxone sodium hydrate (Ro 13-9904 sodium hydrate) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone sodium hydrate is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone sodium hydrate is an inhibitor of Aurora B. Ceftriaxone sodium hydrate has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone sodium hydrate can be used in the study of bacterial infections and meningitis .
|
-
- HY-A0170R
-
|
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
|
Trovafloxacin (Standard) is the analytical standard of Trovafloxacin. This product is intended for research and analytical applications. Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1 .
|
-
- HY-W722081
-
-
- HY-N13966
-
-
- HY-N13929
-
-
- HY-N15083
-
-
- HY-N14374
-
-
- HY-N13946
-
-
- HY-N14233
-
-
- HY-N7141
-
-
- HY-N13973
-
-
- HY-N13974
-
-
- HY-N14909
-
-
- HY-P10182
-
-
- HY-N14322
-
-
- HY-N15021
-
-
- HY-N14514
-
-
- HY-W747994
-
-
- HY-B0724A
-
|
T-3762; Pazufloxacin methanesulfonate; Pazufloxacin mesilate
|
Bacterial
Antibiotic
|
Infection
|
|
Pazufloxacin (T-3761) mesylate is a fluoroquinolone antibiotic.
|
-
- HY-N11857
-
-
- HY-101575
-
|
Acetylkelfizina; Acetylsulfamethoxypyrazine; FI6073
|
Bacterial
Antibiotic
|
Infection
|
|
Acetylazide is a synthetic broad-spectrum bacteriostatic antibiotic.
|
-
- HY-B0724B
-
-
- HY-131477A
-
-
- HY-P5707
-
-
- HY-N14815
-
-
- HY-N6737
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Aureothricin is a dithiolopyrrolone (DTP) antibiotic first isolated from Streptomyces and exhibits relatively broad-spectrum antibiotic activity. Aureothricin can inhibit adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin .
|
-
- HY-W018677S
-
|
|
Antibiotic
|
Infection
|
|
Quinoxaline-d4 is the deuterium labeled Quinoxaline[1]. Quinoxaline is a chemical compound that acts as an intermediate for anti-tuberculosis agent Pyrazinamide. Quinoxaline presents a structure that is similar to quinolone antibiotics[2].
|
-
- HY-112665
-
|
Streptogramin; Mikamycin; RP 7293
|
Antibiotic
Bacterial
|
Infection
|
|
Virginiamycin complex contains two streptogramin antibiotics, virginiamycin M1 and virginiamycin S1 produced by S. virginiae. As a complex, the two antibiotics act synergistically to irreversibly inhibit protein synthesis in bacteria .
|
-
- HY-B1218
-
|
|
Cytochrome P450
Antibiotic
Bacterial
Necroptosis
Apoptosis
|
Infection
Cardiovascular Disease
|
|
Sulfaphenazole is a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme. Sulfaphenazole is a cytoprotective agent against light-induced death of photoreceptors. Sulfaphenazole inhibits light-induced necrosis and mitochondrial stress-initiated apoptosis. Sulfaphenazole is an off patent sulfonamide antibiotic and demonstrates bactericidal activity through enhanced M1 macrophage activity. Sulfaphenazole can significantly reduce infarct size and restore post-ischemic coronary flow following ischemia and reperfusion .
|
-
- HY-B0239
-
|
|
Antibiotic
Bacterial
HIF/HIF Prolyl-Hydroxylase
VEGFR
Autophagy
Apoptosis
Beclin1
JNK
Akt
MMP
|
Infection
Cancer
|
|
Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research .
|
-
- HY-B1434
-
|
7-ACA
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
7-aminocephalosporanic acid (7-ACA) is a HSP90β inhibitor and an antibiotic. 7-Aminocephalosporanic acid is the core chemical structure of the synthesis of cephalosporin antibiotics and an effective β-lactamase inhibitor .
|
-
- HY-129329
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Lankamycin, a macrolide antibiotic, shows moderate antimicrobial activity against several gram-positive bacteria, acting as a synergistic pair with carbocyclic antibiotic Lankacidin C (HY-121412) by binding to the ribosome exit tunnel .
|
-
- HY-E70012
-
|
|
Endogenous Metabolite
|
Infection
Metabolic Disease
|
|
Penicillinase is a beta-lactamase. beta-lactamase enzymes inactivate beta-lactam antibiotics by hydrolyzing the peptide bond of the characteristic four-membered beta-lactam ring rendering the antibiotic ineffective .
|
-
- HY-A0088A
-
-
- HY-B0712R
-
|
Ro 13-9904 free acid (Standard)
|
Bacterial
Antibiotic
GSK-3
Aurora Kinase
|
Infection
Inflammation/Immunology
Cancer
|
|
Ceftriaxone (Standard) is the analytical standard of Ceftriaxone. This product is intended for research and analytical applications. Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis[1][2][3][4][5][6][7].
|
-
- HY-N14539
-
-
- HY-N13967
-
-
- HY-N14748
-
-
- HY-N15060
-
-
- HY-N13954
-
-
- HY-B1128
-
-
- HY-N13953
-
-
- HY-N13968
-
-
- HY-N14138
-
-
- HY-133056
-
-
- HY-B0343A
-
|
A-56620 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Sarafloxacin (hydrochloride) (A-56620 (hydrochloride)) is a quinolone antibiotic agent.
|
-
- HY-N14799
-
-
- HY-N14779
-
-
- HY-A0071
-
-
- HY-127075
-
-
- HY-N14085
-
-
- HY-N14595
-
-
- HY-N14067
-
-
- HY-B1894A
-
-
- HY-N15025
-
-
- HY-19655
-
-
- HY-B1463
-
-
- HY-N13947
-
-
- HY-P5577
-
-
- HY-B1781A
-
|
Sulfachlorpyridazine sodium
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfachloropyridazine (sodium) is a sulfonamide antibiotic that inhibits bacterial growth .
|
-
- HY-N14726
-
-
- HY-B1128A
-
-
- HY-N14282
-
-
- HY-165483
-
-
- HY-128459
-
|
|
Drug Metabolite
|
Others
|
|
N-Demethylerythromycin A is a metabolite of Erythromycin A. Erythromycin A is an antibiotic .
|
-
- HY-N14749
-
-
- HY-B0472
-
-
- HY-122035
-
|
|
Bacterial
|
Infection
|
|
Flambalactone is a degradation product formed by methanolysis of the antibiotic flambamycin.
|
-
- HY-W016420
-
|
MK-0955 sodium
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Fosfomycin (MK-0955) sodium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin sodium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .
|
-
- HY-B1075A
-
|
MK-0955
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .
|
-
- HY-105099R
-
|
KRM-1648 (Standard); ABI-1648 (Standard)
|
Antibiotic
DNA/RNA Synthesis
Bacterial
|
Infection
Inflammation/Immunology
|
|
Rifalazil (Standard) is the analytical standard of Rifalazil. This product is intended for research and analytical applications. Rifalazil (KRM-1648; ABI-1648), a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase[1]. Rifalazil (KRM-1648; ABI-1648) is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis with MIC values from 0.00025 to 0.0025 μg/ml[3]. Rifalazil (KRM-1648; ABI-1648) has the potential for the treatment of Chlamydia infection, Clostridium difficile associated diarrhea (CDAD), and tuberculosis (TB)[2].
|
-
- HY-A0088
-
|
Cefotaxim sodium; HR-756 sodium
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Cefotaxime (Cefotaxim) sodium, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
|
-
- HY-B1381R
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Cefixime (Standard) is the analytical standard of Cefixime. This product is intended for research and analytical applications. Cefixime (FR-17027) is an orally active antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections .
|
-
- HY-119206
-
|
|
Antibiotic
|
Others
|
|
Sulbenicillin is an antibiotic that, in a study of its activity against Pseudomonas aeruginosa infection in mice, showed differences in activity against certain strains compared to other antibiotics, and activity against gentamicin-resistant strains was affected by the strain's own resistance.
|
-
- HY-129788
-
|
|
Antibiotic
|
Others
|
|
Deltamycin A1 is a compound with antibacterial activity. Its structure belongs to the basic macrolide antibiotic family and is different from several other antibiotics of similar structure. Its structure was determined by spectroscopic properties and verified by chemical synthesis.
|
-
- HY-17624
-
|
Neomycin B; Fradiomycin B
|
Bacterial
Antibiotic
|
Infection
|
|
Framycetin (Neomycin B), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections .
|
-
- HY-B1466A
-
|
BAY-f 1353
|
Antibiotic
Bacterial
|
Infection
|
|
Mezlocillin (BAY-f 1353) is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin is active against both gram-negative and gram-positive bacteria. Mezlocillin can be used in bacterial infection research .
|
-
- HY-P2020
-
|
|
Bacterial
|
Infection
|
|
Berninamycin A is a cyclic thiopeptide antibiotic first isolated from S. bernensis. It inhibits protein biosynthesis in Gram positive bacteria through binding with ribosomal subunits. Cyclic thiopeptide antibiotics, including berninamycin A, induce the transcriptional activator TipA in Streptomyces.
|
-
- HY-B1466
-
|
BAY-f 1353 sodium
|
Bacterial
Antibiotic
|
Infection
|
|
Mezlocillin (BAY-f 1353) sodium is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin sodium is active against both gram-negative and gram-positive bacteria. Mezlocillin sodium can be used in bacterial infection research .
|
-
- HY-B1075
-
|
MK-0955 calcium
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Fosfomycin (MK-0955) calcium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin calcium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .
|
-
- HY-B0609
-
|
MK-0955 tromethamine
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Fosfomycin (MK-0955) tromethamine is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin tromethamine shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .
|
-
- HY-125552
-
-
- HY-B1149A
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Bacampicillin hydrochloride is a penicillin antibiotic, is a prodrug of ampicillin with improved oral bioavailability.
|
-
- HY-N14790
-
-
- HY-16251A
-
|
|
Bacterial
|
Infection
|
|
Hetacillin is a beta-lactam antibiotic that is part of the aminopenicillin family.
|
-
- HY-B0269
-
-
- HY-17506A
-
-
- HY-119764
-
|
|
Antibiotic
|
Others
|
|
Ikarugamycin is an antibiotic and a inhibitor of clathrin-mediated endocytosis (CME) .
|
-
- HY-B1743
-
|
CL13900
|
Bacterial
Antibiotic
Parasite
|
Infection
|
|
Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.
|
-
- HY-123474
-
-
- HY-117849
-
|
|
Antibiotic
|
Infection
|
|
Neutramycin is a neutral macrolide antibiotic with a complex composition and classification .
|
-
- HY-N14544
-
|
|
Fungal
|
Infection
|
|
Orchinol is an aromatic derivative of antibiotic and has antifungal activity .
|
-
- HY-N5172
-
-
- HY-N14411
-
-
- HY-N6665A
-
-
- HY-B1387
-
-
- HY-121245
-
-
- HY-N14373
-
-
- HY-131093
-
|
Enramycin
|
Antibiotic
|
Infection
|
|
Enduracidin (Enramycin) is a polypeptide antibiotic produced by Streptomyces fungicides .
|
-
- HY-109755
-
-
- HY-N14913
-
-
- HY-17506
-
-
- HY-N13875
-
-
- HY-B1149
-
-
- HY-148910
-
|
|
Antibiotic
|
Infection
|
|
Paromamine is an antibiotic that recognizes ribosomal RNA (rRNA) components .
|
-
- HY-B1381AR
-
|
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
Cancer
|
|
Cefixime (trihydrate) (Standard) is the analytical standard of Cefixime (trihydrate). This product is intended for research and analytical applications. Cefixime trihydrate (FR-17027 trihydrate) is an antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections .
|
-
- HY-17558
-
|
Nebramycin II
|
Bacterial
Antibiotic
|
Infection
|
|
Apramycin (Nebramycin II) is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin is a potential anti-drug-resistance antibiotic .
|
-
- HY-168204
-
|
|
Bacterial
Fungal
|
Infection
|
|
3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid (compound J1) is a potent antimicrobial agent. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid shows anti-gram-positive bacteria and fungi activity. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid can be used as antibiotic adjuvants. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic disrupts the bacterial cell membrane, inserts into the DNA, and binds to DNA gyrase. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic reduces microbial count in a mouse MRSA skin infection model and accelerates wound healing .
|
-
- HY-17624A
-
|
Neomycin B sulfate; Fradiomycin B sulfate
|
Antibiotic
Bacterial
|
Infection
|
|
Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin sulfate competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin sulfate inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin sulfate, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections .
|
-
- HY-A0110AR
-
|
CTM-HE hydrochloride (Standard); SCE-2174 hydrochloride (Standard)
|
Bacterial
Antibiotic
|
Infection
|
|
Cefotiam hexetil (hydrochloride) (Standard) is the analytical standard of Cefotiam hexetil (hydrochloride). This product is intended for research and analytical applications. Cefotiam hexetil hydrochloride (CTM-HE) is an oral third-generation cephalosporin, which is a proagent of cefotiam, but has no anti-bacterial property. Cefotiam is an antibiotic[1].
|
-
- HY-N14134
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Deoxyfrenolicin is a quinone antibiotic that can be isolated from the fermentation broth of the Streptomyces roseofulvus strain AM-3867. Deoxyfrenolicin belongs to the frenolicin class of antibiotics. Deoxyfrenolicin exhibits antibacterial activity in vitro and can effectively inhibit the activity of Mycoplasma gallisepticum .
|
-
- HY-B0239R
-
|
|
Antibiotic
Bacterial
HIF/HIF Prolyl-Hydroxylase
VEGFR
Autophagy
Apoptosis
Beclin1
JNK
Akt
MMP
|
Infection
Cancer
|
|
Chloramphenicol (Standard) is the analytical standard of Chloramphenicol. This product is intended for research and analytical applications. Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research .
|
-
- HY-B1218R
-
|
|
Cytochrome P450
Antibiotic
Bacterial
Necroptosis
Apoptosis
|
Infection
Cardiovascular Disease
|
|
Sulfaphenazole (Standard) is the analytical standard of Sulfaphenazole. This product is intended for research and analytical applications. Sulfaphenazole is a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme. Sulfaphenazole is a cytoprotective agent against light-induced death of photoreceptors. Sulfaphenazole inhibits light-induced necrosis and mitochondrial stress-initiated apoptosis. Sulfaphenazole is an off patent sulfonamide antibiotic and demonstrates bactericidal activity through enhanced M1 macrophage activity. Sulfaphenazole can significantly reduce infarct size and restore post-ischemic coronary flow following ischemia and reperfusion .
|
-
- HY-B0712S1
-
|
Ro 13-9904-13C2,d3 triethylammonium salt
|
Antibiotic
Aurora Kinase
GSK-3
Bacterial
Isotope-Labeled Compounds
|
Infection
Inflammation/Immunology
Cancer
|
|
Ceftriaxone- 13C2,d3 triethylammonium salt is 13C and deuterated labeled Ceftriaxone (HY-B0712). Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC50 value of 0.78 mM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .
|
-
- HY-A0062R
-
|
|
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Telithromycin (Standard) is the analytical standard of Telithromycin. This product is intended for research and analytical applications. Telithromycin (HMR3647) is a novel ketolide antibiotic that structurally resembles macrolides. Telithromycin belongs to the ketolide family that is characterized by a keto group at position 3 of the macrolide ring and is active against bacteria causing community-acquired pneumonia, acute exacerbation of chronic bronchitis, and acute sinusitis. Telithromycin also has similar immunomodulatory effects as macrolides. Telithromycin can be used for the research of respiratory infections including bronchial asthma .
|
-
- HY-122146
-
-
- HY-N5173
-
-
- HY-129339
-
|
|
Fungal
|
Infection
Cancer
|
|
Akrobomycin is an anthracycline antibiotic. Akrobomycin shows antimicrobial and antitumor activities .
|
-
- HY-N14615
-
-
- HY-B1743A
-
-
- HY-N14664
-
-
- HY-N15017
-
-
- HY-N14891
-
-
- HY-N15396
-
-
- HY-131150
-
-
- HY-13644A
-
|
Spanidin; NKT-01; BMS181173
|
Antibiotic
|
Inflammation/Immunology
Cancer
|
|
Gusperimus trihydrochloride (Spanidin) is a derivative of the antitumor antibiotic spergualin with immunosuppressant activity .
|
-
- HY-N14733
-
-
- HY-B0490
-
-
- HY-Z17187
-
-
- HY-N14087
-
-
- HY-141441
-
|
|
Bacterial
|
Infection
|
|
Novobiocic acid is an aglycone form of the antibiotic Novobiocin (HY-B0425).
|
-
- HY-107213
-
-
- HY-N6665
-
-
- HY-N14086
-
-
- HY-172250
-
-
- HY-126662
-
|
|
Bacterial
|
Infection
|
|
Netzahualcoyone is a triterpenoid compound isolated from the Celastraceae plant family. Netzahualcoyone exhibits broad-spectrum antibiotic activity against Gram-positive bacteria and yeasts, but is not active against Gram-negative bacteria. Netzahualcoyone can be utilized in the development of antibiotics and for studying antimicrobial mechanisms .
|
-
- HY-10394
-
|
PNU-100766
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics .
|
-
- HY-N13969
-
-
- HY-142058
-
-
- HY-B1300
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefonicid sodium is a broadspectrum cephalosporin antibiotic which inhibits the formation of the bacterial cell wall.
|
-
- HY-N13958
-
-
- HY-A0256A
-
-
- HY-169506
-
-
- HY-118029
-
|
|
Antibiotic
|
Infection
|
|
Saroaspidin A is an antibiotic, which can be isolated from Hypericum japonicum thunb .
|
-
- HY-125074
-
|
|
Antibiotic
|
Infection
|
|
PNU 142300 is an inactive metabolite of the oxazolidinone antibiotic Linezolid (HY-10394).
|
-
- HY-U00214
-
|
R835; S25930
|
Antibiotic
Bacterial
|
Infection
|
|
Ibafloxacine (R835) is a fluoroquinolone antibiotic agent that is developed exclusively for veterinary use.
|
-
- HY-W714019
-
-
- HY-N14819
-
-
- HY-B0465
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Oxacillin sodium monohydrate is an antibiotic similar to Flucloxacillin used in resistant staphylococci infections study .
|
-
- HY-B0506
-
-
- HY-129814
-
-
- HY-125049
-
-
- HY-W748035
-
-
- HY-N13987
-
-
- HY-N13972
-
-
- HY-127142
-
-
- HY-B0992
-
-
- HY-N13952
-
-
- HY-N13985
-
-
- HY-136968
-
-
- HY-B0915
-
|
CP-104354
|
Bacterial
Antibiotic
|
Infection
|
|
Orbifloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic which is approved for use in dogs.
|
-
- HY-167256
-
-
- HY-W739930
-
|
|
Antibiotic
|
Infection
|
|
Desmethyl ofloxacin hydrochloride is a metabolite of the fluoroquinolone antibiotic Ofloxacin (HY-B0125).
|
-
- HY-N14545
-
-
- HY-N15100
-
-
- HY-N13983
-
-
- HY-B1824
-
-
- HY-N14964
-
-
- HY-N14698
-
-
- HY-N13956
-
-
- HY-N14230
-
-
- HY-B0417A
-
-
- HY-N14182
-
-
- HY-106257S
-
|
|
Isotope-Labeled Compounds
Antibiotic
Bacterial
|
Infection
|
|
Ceftolozane-d6 TFA is a deuterated labeled Ceftolozane TFA (HY-106257A). Ceftolozane TFA is a cephalosporin antibiotic that can be used to inhibit Gram-negative bacterial infections. Ceftolozane TFA can be used to synthesize new antibiotic that are more potent and safer .
|
-
- HY-A0088S
-
|
Cefotaxim-d3 sodium; HR-756-d3 sodium
|
Isotope-Labeled Compounds
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Cefotaxime-d3 (sodium) is the deuterium labeled Cefotaxime (sodium salt). Cefotaxime sodium salt, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria[1][2][3][4][5].
|
-
- HY-122494A
-
-
- HY-N14800
-
-
- HY-N14979
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Dermostatin A is a polyene antibiotic with antifungal activity that can be used in the study of fungal infections .
|
-
- HY-N14152
-
-
- HY-B1166
-
-
- HY-B0108
-
-
- HY-114749
-
-
- HY-N14717
-
-
- HY-N15041
-
-
- HY-N14185
-
-
- HY-N14183
-
-
- HY-118983
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Pivampicillin hydrochloride is a penicillin antibiotic. Pivampicillin hydrochloride is a prodrug of Ampicillin (HY-B0522) .
|
-
- HY-N14902
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Mimosamycin is an antibiotic. Mimosamycin has activity against mycobacteria and streptomyces resistant strains .
|
-
- HY-N12908
-
|
Verrucarin H
|
Antibiotic
|
Infection
|
|
Roridin H (Verrucarin H) is an antibiotic and can be isolated from Myrothecium verrucaria .
|
-
- HY-131098
-
|
|
Antibiotic
|
Infection
|
|
Enduracidin A is a major component of Enduracidin. Enduracidin is a polypeptide antibiotic produced by Streptomyces fungicides .
|
-
- HY-N14937
-
-
- HY-N14679
-
-
- HY-N13871
-
-
- HY-N14140
-
-
- HY-N14844
-
-
- HY-N14691
-
-
- HY-122447
-
|
|
Antibiotic
|
Infection
|
|
Saroaspidin C (Compound 3) is an antibiotic that can be isolated from Sarothra japonica .
|
-
- HY-N7139A
-
|
Benzathine benzylpenicillin
|
Bacterial
Antibiotic
|
Infection
|
|
Penicillin G benzathine (Benzathine benzylpenicillin) is an antibiotic against many bacterial infections .
|
-
- HY-W008923
-
-
- HY-N14841
-
-
- HY-N14308
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aspiculamycin, a cytosine nucleoside, is an antibiotic. Aspiculamycin has a broad spectrum of antibacterial activity .
|
-
- HY-N14149
-
|
|
Antibiotic
|
Infection
|
|
Cystothiazole B is a bithiazole-type antibiotic and can be extracted from Cystobacter fuscus .
|
-
- HY-N14589
-
-
- HY-119011
-
-
- HY-125723
-
-
- HY-N14434
-
-
- HY-119280
-
-
- HY-N14682
-
-
- HY-107027
-
|
|
Antibiotic
|
Infection
|
|
Polymyxin E2 sulfate is an antibiotic produced by the soil bacterium Bacillus polymyxa .
|
-
- HY-119759
-
|
|
Fungal
|
Infection
|
|
Lipoxamycin is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC50 of 21 nM .
|
-
- HY-14881A
-
|
R403323; TMC207 fumarate; R207910 fumarate
|
Bacterial
Antibiotic
|
Infection
|
|
Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
|
-
- HY-N15024
-
-
- HY-A0256B
-
-
- HY-P0092
-
-
- HY-N13890
-
-
- HY-10004
-
-
- HY-N14412
-
-
- HY-N12906
-
-
- HY-100496
-
|
4'-Fluoro-5'-O-sulfamoyladenosine; NSC 521007
|
Bacterial
|
Infection
|
|
Nucleocidin is an antitrypanosomal antibiotic, inhibiting the transfer of labeled amino acid from S-RNA to protein.
|
-
- HY-116617R
-
|
|
Drug Metabolite
|
Others
|
|
Cefotaxime (Standard) is the analytical standard of Cefotaxime. This product is intended for research and analytical applications. Cefotaxime, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
|
-
- HY-A0088AR
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Cefotaxime (Standard) is the analytical standard of Cefotaxime. This product is intended for research and analytical applications. Cefotaxime, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
|
-
- HY-N13019
-
|
|
Antibiotic
|
Infection
|
|
Elmycin D is an antibiotic, which can be isolated from Streptomyces cellulosae ssp. griseoincarnatus .
|
-
- HY-114658
-
-
- HY-100436
-
|
ACT-179811
|
Bacterial
Antibiotic
|
Infection
|
|
Cadazolid (ACT-179811) is a new oxazolidinone antibiotic with potent activity against Clostridium difficile.
|
-
- HY-129285
-
-
- HY-B0810
-
|
FL-1039
|
Bacterial
Antibiotic
|
Infection
|
|
Pivmecillinam (FL-1039) is an orally active proagent of mecillinam, an extended-spectrum penicillin antibiotic.
|
-
- HY-N13883
-
-
- HY-122490
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Lincomycin (compound II) is a new polyether antibiotic that can be isolated from streptoverticillium olivoreticuli .
|
-
- HY-137927
-
|
|
Antibiotic
|
Others
|
|
Benapenem is a carbapenem-type agent that belongs to the broad-spectrum β-lactam antibiotic class.
|
-
- HY-N13887
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aerocyanidin is an antibiotic containing an isonitrile group, which is mainly effective against Gram-positive bacteria.
|
-
- HY-N14681
-
-
- HY-N14599
-
-
- HY-N14611
-
|
Pyrazomycin B
|
Antibiotic
Bacterial
|
Infection
|
|
Pyrazomycin II (Pyrazomycin B) is an antibiotic. Pyrazomycin is a competitive inhibitor of pyrimidine nucleoside metabolism .
|
-
- HY-B0810A
-
|
FL-1039 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Pivmecillinam hydrochloride (FL-1039 hydrochloride) is an orally active proagent of mecillinam, an extended-spectrum penicillin antibiotic.
|
-
- HY-108988
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Albicidin is a peptide antibiotic with activity against various Gram-positive and Gram-negative microorganisms .
|
-
- HY-N14825
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Erythroskyrine is a heterocyclic antibiotic with weak activity against Gram-positive bacteria such as Staphylococcus aureus .
|
-
- HY-P1695
-
|
Ro 09-0198
|
Antibiotic
Bacterial
|
Infection
|
|
Cinnamycin (Ro 09-0198) is a tetracyclic peptide antibiotic that binds specifically to phosphatidylethanolamine (PE) .
|
-
- HY-N15127
-
-
- HY-N14683
-
-
- HY-112639
-
-
- HY-131099
-
|
|
Antibiotic
|
Infection
|
|
Enduracidin B is a major component of Enduracidin. Enduracidin is a polypeptide antibiotic produced by Streptomyces fungicides .
|
-
- HY-N14187
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aspergillic acid is an antibiotic found in Aspergillus flavus. Aspergillic acid has a broad spectrum of antibacterial activity .
|
-
- HY-125070
-
|
|
Antibiotic
|
Infection
|
|
Racemomycin C is an analog of the antibiotic soramycin and is probably the 0-methyl derivative of racemomycin B.
|
-
- HY-N14014
-
-
- HY-106702A
-
-
- HY-127072
-
|
|
Antibiotic
|
Infection
|
|
Amicoumacin A is a antibiotic that can be isolated from the culture of Bacillus pumilus BN-103 .
|
-
- HY-119759A
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Lipoxamycin hemisulfate is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC50 of 21 nM .
|
-
- HY-N12223
-
-
- HY-W780199
-
-
- HY-N14718
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Porothramycin A is an antibiotic. Porothramycin A has activity against Gram-positive bacteria and anaerobic bacteria .
|
-
- HY-N14727
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Primycin is a macrolide antibiotic. Primycin is active against Gram-positive bacteria, mycobacteria and protozoa .
|
-
- HY-118221
-
-
- HY-N14980
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Dermostatin B is a polyene antibiotic with antifungal activity that can be used in the study of fungal infections .
|
-
- HY-B0408A
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Clindamycin (hydrochloride) is a semisynthetic lincosamide antibiotic, which inhibits protein synthesis by acting on the 50S ribosomal.
|
-
- HY-N15034
-
-
- HY-N13900
-
-
- HY-B0308
-
|
CI-978; AT-4140
|
Bacterial
Antibiotic
|
Infection
|
|
Sparfloxacin (CI-978) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity .
|
-
- HY-A0088R
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Cefotaxime (sodium) (Standard) is the analytical standard of Cefotaxime (sodium). This product is intended for research and analytical applications. Cefotaxime (Cefotaxim) sodium, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
|
-
- HY-112665R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Virginiamycin Complex (Standard) is the analytical standard of Virginiamycin Complex. This product is intended for research and analytical applications. Virginiamycin complex contains two streptogramin antibiotics, virginiamycin M1 and virginiamycin S1 produced by S. virginiae. As a complex, the two antibiotics act synergistically to irreversibly inhibit protein synthesis in bacteria .
|
-
- HY-118132
-
|
|
Antibiotic
|
Infection
|
|
LL-Z1220 is a novel antibiotic with the structure of 2-(3,8-dioxopentacyclo[5.1.0.0^~^~]oct-5-en-5-yl)-4H-pyran-4-one. This appears to be the first reported natural product containing a benzene dioxide group. This antibiotic readily undergoes valence isomerization to form 1,4-dioxopentacyclo. The chemical and spectroscopic properties of the antibiotic suggest that the benzene dioxide has a cis configuration.
|
-
- HY-B1075R
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Fosfomycin (calcium) (Standard) is the analytical standard of Fosfomycin (calcium). This product is intended for research and analytical applications. Fosfomycin (MK-0955) calcium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin calcium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .
|
-
- HY-17624AR
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Framycetin (sulfate) (Standard) is the analytical standard of Framycetin (sulfate). This product is intended for research and analytical applications. Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin sulfate competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin sulfate inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin sulfate, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections .
|
-
- HY-W077634
-
|
AHBA
|
Drug Intermediate
|
Infection
|
|
3-Amino-5-hydroxybenzoic acid is a biosynthetic precursor of the mC7N unit of ansamycin antibiotics, including ansatrienin A and geldanamycin, as well as the antitumor antibiotic mitomycin C. 3-Amino-5-hydroxybenzoic acid may be an early intermediate in the shikimic acid pathway from glucose .
|
-
- HY-W654101
-
|
Cefotaxim-d3; HR-756-d3
|
Isotope-Labeled Compounds
Antibiotic
Bacterial
|
Infection
|
|
Cefotaxime-d3 is the deuterium labeled Cefotaxime (HY-A0088A). Cefotaxime is the β-lactamase stable cephalosporin and the third-generation cephalosporin antibiotic. Cefotaxime possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
|
-
- HY-105846
-
|
|
DNA/RNA Synthesis
Bacterial
Antibiotic
|
Cancer
|
|
Nogalamycin is an anthracyclinone antibiotic. Nogalamycin is a potent antibiotic against Gram-positive bacteria, also has cytotoxicity against certain tumor cells. Nogalamycin is produced by Streptomyces nogalater var. Nogalater. Nogalamycin selectively inhibits RNA synthesis after binding to DNA template. Nogalamycin can be used for researching anticancer .
|
-
- HY-N6670
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefotetan is a semisynthetic cephamycin antibiotic that exerts its bactericidal effects by inhibition of cell-wall synthesis .
|
-
- HY-105350
-
|
Ostreogrycin B2 ; Vernamycin Bβ
|
Antibiotic
Bacterial
|
Infection
|
|
Pristinamycin IB (Ostreogrycin B2) is an ester peptide antibiotic with anti-Gram-positive bacteria effects .
|
-
- HY-N14046
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Celesticetin B is an antibiotic. Celesticetin B is mainly antibacterial against Gram-positive microorganisms .
|
-
- HY-N7115
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sultamicillin is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .
|
-
- HY-B0706A
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Flomoxef sodium is a oxacephem group antibiotic, with excellent activity against various Gram-positive bacteria .
|
-
- HY-126783
-
|
11-Deoxycandicidin D
|
Antibiotic
|
|
|
Levorin A0 is a Levorin component. Levorin is an aromatic polyene (heptaene) antibiotic with high antifungal activity.
|
-
- HY-N14826
-
-
- HY-B1190
-
|
BL-S 578
|
Bacterial
Antibiotic
|
Infection
|
|
Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.
|
-
- HY-N13878
-
-
- HY-N7111
-
|
Sultamicillin (tosilate)
|
Bacterial
Antibiotic
|
Infection
|
|
Sultamicillin tosylate is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .
|
-
- HY-122505
-
-
- HY-106571
-
|
Ro 19-5248; T-2588
|
Bacterial
Antibiotic
|
Infection
|
|
Cefteram pivoxil (Ro 19-5248), an orally active cephalosporin antibiotic, is used for bacterial infections .
|
-
- HY-N14372
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Methymycin is a macrolide antibiotic with activity against Gram-positive bacteria and a few Gram-negative bacteria .
|
-
- HY-N14320
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Lactaroviolin is an aromatic derivative antibiotic. Lactaroviolin can inhibit the growth of Mycobacterium tuberculosis, but the effect is not strong .
|
-
- HY-B2072A
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cephaloridine hydrate is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity .
|
-
- HY-N6728
-
|
Fumigacin
|
Bacterial
Antibiotic
|
Infection
|
|
Helvolic acid (Fumigacin) is an antibiotic isolated from Xylaria sp, active against the Gram-positive bacteria .
|
-
- HY-N14995
-
-
- HY-121620
-
-
- HY-N14895
-
-
- HY-127007
-
|
|
Antibiotic
|
Infection
|
|
Okilactomycin is a lactone group antibiotic isolated from the culture filtrate of a strain of actinomycetes (Streptomyces species) .
|
-
- HY-N10585
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Malacidin B is a macrocyclic lipopeptide antibiotic that shows antibacterial activity in a calcium-dependent manner .
|
-
- HY-132915
-
|
|
Bacterial
|
Infection
|
|
Anti gram-positive/negative bacteria agent 1 is an antibiotic conjugate with an artificial MECAM-based siderophore.
|
-
- HY-N10449
-
-
- HY-108874
-
|
Levorin; Vanobid; Candimon
|
Antibiotic
Fungal
Bacterial
|
Infection
|
|
Candicidin is a polyene antifungal antibiotic agent and can be isolated from Streptomyces griseus or Actinomyces levoris .
|
-
- HY-N14058
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Halymecin A is an antibiotic found in Marine microbes. Halymecin A had only weak antibacterial and fungal activity .
|
-
- HY-155364
-
-
- HY-Z7555
-
-
- HY-N14711
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Himalomycin A is an anthraquinone antibiotic with strong activity against Staphylococcus aureus, Escherichia coli and Streptomyces vuridochromogenes .
|
-
- HY-B0706
-
-
- HY-N7139B
-
|
Benzathine benzylpenicillin tetrahydrate
|
Antibiotic
Bacterial
|
Infection
|
|
Penicillin G benzathine tetrahydrate (Benzathine benzylpenicillin tetrahydrate) is an antibiotic against many bacterial infections .
|
-
- HY-131054
-
-
- HY-135394
-
|
|
Drug Metabolite
Antibiotic
|
Infection
|
|
3-Desacetyl Cefotaxime lactone is the active metabolite of Cefotaxime. Cefotaxime sodium salt is a third-generation cephalosporin antibiotic.
|
-
- HY-B2072
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cephaloridine is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity .
|
-
- HY-N14986
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Methylenomycin A is a cyclopentanone derived antibiotic that is effective against both Gram-negative and Gram-positive bacteria .
|
-
- HY-B0502
-
-
- HY-N14445
-
-
- HY-N14609
-
-
- HY-16752A
-
|
MK-7655 sodium
|
Beta-lactamase
Bacterial
|
Infection
|
|
Relebactam sodium (MK-7655 sodium) is a potent and selective β-lactamase inhibitor with the activity of delaying the development of bacterial resistance to antibiotics. Relebactam sodium can bind to a variety of β-lactamases, thereby improving the efficacy of β-lactam antibiotics. Relebactam sodium shows good application potential in inhibiting complicated bacterial infections .
|
-
- HY-B1466R
-
|
BAY-f 1353 sodium (Standard)
|
Bacterial
Antibiotic
|
Infection
|
|
Mezlocillin (sodium) (Standard) is the analytical standard of Mezlocillin (sodium). This product is intended for research and analytical applications. Mezlocillin (BAY-f 1353) sodium is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin sodium is active against both gram-negative and gram-positive bacteria. Mezlocillin sodium can be used in bacterial infection research[1][2].
|
-
- HY-B1434R
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
7-Aminocephalosporanic acid (Standard) is the analytical standard of 7-Aminocephalosporanic acid. This product is intended for research and analytical applications. 7-aminocephalosporanic acid (7-ACA) is a HSP90β inhibitor and an antibiotic. 7-Aminocephalosporanic acid is the core chemical structure of the synthesis of cephalosporin antibiotics and an effective β-lactamase inhibitor .
|
-
- HY-118043
-
|
|
Antibiotic
|
Infection
|
|
RK-1441B is an anti-phage antibiotic produced by Streptomyces sp. RK-1441 and belongs to the pyrrolo[1,4]benzodiazepine class. RK-1441B has antiphage activity but no significant antimicrobial activity against a supersusceptible E. coli strain to an antitumor antibiotic. RK-1441B is inactive in vitro and may be converted to the active form in the host organism. Its fellow antibiotic RK-1441A can form an adduct with guanine residues in the DNA chain to exert resistance .
|
-
- HY-N15104
-
-
- HY-N14333
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Halomicin A is an ansamycin antibiotic. Halomicin A has activity against Gram-positive and Gram-negative bacteria (individual) .
|
-
- HY-N14469
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Sakyomicin C is a Benzoquinone antibiotic. Sakyomicin C has activity against Gram-positive bacteria and mycobacteria .
|
-
- HY-N14784
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Dechloromycorrhizin A is an antibiotic with weak activity against Gram-positive bacteria, yeasts and mildew, and strong nematocidal activity .
|
-
- HY-N14987
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Methylenomycin b is a cyclopentanone derived antibiotic that is effective against both Gram-negative and Gram-positive bacteria .
|
-
- HY-112853
-
|
FR-31564
|
Bacterial
Antibiotic
|
Infection
|
|
Fosmidomycin sodium salt is a phosphonic acid antibiotic and a antimalarial agent, which is active against both Gram-negative and Gram-positive bacteria.
|
-
- HY-118651
-
|
|
Bacterial
|
Infection
|
|
Griseoluteic acid, a phenazine antibiotic, is originally isolated from S. griseoluteus. Griseoluteic acid is a breakdown product of griseolutein A and B .
|
-
- HY-P2311
-
-
- HY-121473
-
-
- HY-N15039
-
-
- HY-N14246
-
-
- HY-U00154R
-
|
SKF81367 (Standard)
|
Bacterial
Antibiotic
|
Infection
|
|
Cefuracetime (Standard) is the analytical standard of Cefuracetime. This product is intended for research and analytical applications. SKF81367 is a cephalosporin antibiotic.
|
-
- HY-B0474
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Tetracycline (hydrochloride) is a broad-spectrum antibiotic, exhibiting activity against a wide range of gram-positive and gram-negative bacteria.
|
-
- HY-17025
-
|
Ansamycin; LM-427
|
Bacterial
Antibiotic
|
Infection
|
|
Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.
|
-
- HY-N14981
-
-
- HY-123444
-
|
|
Antibiotic
|
Others
|
|
Kijimicin is a polyether antibiotic, and its specific mechanism of activity and application details are not described in detail from the existing information.
|
-
- HY-17565
-
|
Bleomycin sulfate
|
DNA/RNA Synthesis
Antibiotic
|
Cancer
|
|
Bleomycin sulfate is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin sulfate is an antitumor antibiotic .
|
-
- HY-A0253
-
|
Cephacetrile; Cephacetril
|
Bacterial
Antibiotic
|
Infection
|
|
Cefacetrile (Cephacetrile) is a broad-spectrum antibiotic that is effective in gram-positive and gram-negative bacterial infection .
|
-
- HY-123174
-
|
AY-24668
|
Antibiotic
Fungal
|
Infection
|
|
Demethoxyrapamycin (AY-24668) is a potent antifungal antibiotic which is co-produced with rapamycin by Streptomyces hygroscopicus .
|
-
- HY-136953
-
|
|
Antibiotic
|
Infection
|
|
LL-BM123γ1 is a potent broad spectrum glycocinnamoylspermidine antibiotic .
|
-
- HY-P5575
-
-
- HY-B0356AS
-
|
Bay-09867-dd8 hydrochloride hydrate
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Ciprofloxacin-d8 (hydrochloride hydrate) is the deuterium labeled Ciprofloxacin hydrochloride monohydrate. Ciprofloxacin hydrochloride monohydrate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
|
-
- HY-129669
-
|
|
Antibiotic
|
Infection
|
|
Landomycin A is a notable antibiotic belonging to the angucycline class, characterized by its hexasaccharide structure, and is derived from Streptomyces sp.
|
-
- HY-N11874
-
|
|
Bacterial
|
Infection
|
|
Staphyloferrin A is a siderophore protein that can be combined with antibiotics to study drug-resistant bacteria that cause skin diseases .
|
-
- HY-N14341
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Mannosyl glucosaminide is an aminoglycoside antibiotic. Mannosyl glucosaminide has anti-bacterium, mycobacterium and beer yeast effects .
|
-
- HY-B0671S3
-
-
- HY-N14894
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Promothiocin B is an antibiotic. The minimum induction concentration of Promothiocin B for tipA promoter is 0.1 μg/mL .
|
-
- HY-W748030
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Griseoviridin is an Estopeptide antibiotic. Griseoviridin has anti-Gram positive bacteria, negative bacteria (individual) activity .
|
-
- HY-P5576
-
-
- HY-108879
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefotetan disodium is a semisynthetic cephamycin antibiotic that exerts its bactericidal effects by inhibition of cell-wall synthesis .
|
-
- HY-P2328
-
-
- HY-135577
-
|
|
Drug Metabolite
|
Infection
|
|
β-Apooxytetracycline is a degradation product of Oxytetracycline (HY-B0275). Oxytetracycline is a widespread antibiotic .
|
-
- HY-N14684
-
-
- HY-126606
-
|
|
Antibiotic
|
Infection
|
|
Isochlortetracycline is an inactive alkaline degradation product of the Chlortetracycline (HY-B1327A) (broad-spectrum antibiotic) .
|
-
- HY-131152
-
-
- HY-125546
-
|
|
Antibiotic
|
Infection
|
|
Erythromycin C is an antibiotic. Erythromycin C could be isolated from the fermentation process of the penicillium Streptomyces erythreus .
|
-
- HY-100997
-
|
A82846B; LY 264826; PA 45052A
|
Antibiotic
|
Infection
|
|
Chloroorienticin A (A82846B) is a glycopeptide antibiotic. Chloroorienticin A exhibits excellent activity against staphylococci and streptococci .
|
-
- HY-B0522
-
|
D-(-)-α-Aminobenzylpenicillin
|
Bacterial
Antibiotic
|
Infection
|
|
Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.
|
-
- HY-129728
-
-
- HY-N14896
-
-
- HY-B0356BS
-
|
Bay-09867-d8 hydrochloride monohydrate
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Ciprofloxacin-d8 (hydrochloride monohydrate) is the deuterium labeled Ciprofloxacin (hydrochloride monohydrate). Ciprofloxacin hydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
|
-
- HY-N14978
-
-
- HY-17626B
-
|
WCK-2349 hydrochloride
|
Antibiotic
|
Infection
|
|
Alalevonadifloxacin (hydrochloride) (WCK-2349 (hydrochloride)) is a oraaly active anti-methicillin-resistant Staphylococcus aureus (MRSA) antibiotic .
|
-
- HY-N15026
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
13-Hydroxyglucopiericidin A is an antibiotic. 13-Hydroxyglucopiericidin A has strong anti-tumor cell activity .
|
-
- HY-N14719
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Porothramycin B is an antibiotic. Porothramycin B has activity against Gram-positive bacteria and anaerobic bacteria .
|
-
- HY-121482
-
|
STA-21
|
STAT
|
Inflammation/Immunology
Cancer
|
|
(+)-Ochromycinone is a natural antibiotic that potently inhibits STAT3. (+)-Ochromycinone is used in the researches of cancers and psoriasis .
|
-
- HY-122207
-
|
|
Antibiotic
|
Infection
|
|
Erythromycin A enol ether is an acidic degradation product of Erythromycin A (macrolide antibiotic) and has no antibacterial effect .
|
-
- HY-B1366A
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Meclocycline is a tetracycline antibiotic with broad-spectrum antibacterial activities, preventing skin bacterial infections such as acne vulgarisis .
|
-
- HY-125618
-
|
T-2636 D
|
Antibiotic
Bacterial
|
Infection
|
|
Lankacidinol A (T-2636 D) is an antibiotic, and shows antibacterial activity against Gram-positive bacteria .
|
-
- HY-N14702
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
2-Hydroxygentamicin B is a 3 aminoglycoside antibiotic with anti-Gram-positive and negative bacteria activity .
|
-
- HY-10394R
-
|
PNU-100766 (Standard)
|
Bacterial
Antibiotic
|
Infection
|
|
Linezolid (Standard) is the analytical standard of Linezolid. This product is intended for research and analytical applications. Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics .
|
-
- HY-N14803
-
-
- HY-N14704
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
2-Hydroxygentamicin C1 is an antibiotic of the gentamicin group with anti-Gram-positive and negative bacteria activity .
|
-
- HY-B0888
-
|
Sulphacetamide sodium monohydrate
|
Antibiotic
Bacterial
Fungal
|
Infection
Inflammation/Immunology
|
|
Sulfacetamide (Sulphacetamide) sodium monohydrate is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide sodium monohydrate has antifungal and antibacterial activities .
|
-
- HY-N14252
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Melithiazol N is an antibiotic. Melithiazole N is a β-methoxyacrylate (MOA) inhibitor with strong anti-agent activity .
|
-
- HY-N14910
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Actiketal is a glutarimide antibiotic that inhibits the incorporation of [ 3H]thymidine into EGF-stimulated Balb/MK cells .
|
-
- HY-N14251
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Melithiazol K is an antibiotic. Melithiazole K is a β-methoxyacrylate (MOA) inhibitor with strong anti-agent activity .
|
-
- HY-13725
-
-
- HY-N14701
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
2-Hydroxygentamicin A3 is a 3 aminoglycoside antibiotic with anti-Gram-positive and negative bacteria activity .
|
-
- HY-B0671R
-
|
|
Bacterial
Autophagy
Antibiotic
|
Infection
Cancer
|
|
Vancomycin (Standard) is the analytical standard of Vancomycin. This product is intended for research and analytical applications. Vancomycin is an antibiotic for the treatment of bacterial infections.
|
-
- HY-N14714
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Gunacin is a quinone antibiotic. Gunacin has strong activity against Gram-positive bacteria, negative bacteria and mycoplasma .
|
-
- HY-B1366
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Meclocycline Sulfosalicylate Salt is a tetracycline antibiotic with broad-spectrum antibacterial activities, preventing skin bacterial infections such as acne vulgaris .
|
-
- HY-N14336
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Halomicin D is an ansamycin antibiotic. Halomicin A has activity against Gram-positive and Gram-negative bacteria (individual) .
|
-
- HY-125560
-
-
- HY-B0576
-
-
- HY-134518
-
|
Erythromycin A oxime; Erythromycin-9-oxime
|
Drug Intermediate
|
Infection
|
|
Erythromycin oxime is an intermediate of Azithromycin (HY-17506). Azithromycin is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
|
-
- HY-N14261
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Angiolam A is an antibiotic found in Angiococcus disciformis. Angiolam A exhibits notable antibacterial activity against Gram-positive bacteria .
|
-
- HY-101128
-
|
FR2054
|
Bacterial
Antibiotic
|
Infection
|
|
Bicyclomycin benzoate is an antibiotic exhibiting activity against a broad spectrum of Gram-negative bacteria and against the Gram-positive bacterium.
|
-
- HY-N13995
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Serratamolide is a depsipeptide antibiotic. Serratamolide has anti-Gram-positive bacteria, mycobacteria and fungi activity, but the activity is weak .
|
-
- HY-P5572
-
-
- HY-P10158
-
|
Porcine cathelicidin PMAP-36
|
Bacterial
|
Infection
|
|
PMAP-36 is an antimicrobial peptide, with sequence of GRFRRLRKKTRKRLKKIGKVLKWIPPIVGSIPLGCG. PMAP-36 with traditional antibiotics can enhance .
|
-
- HY-N14175
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Epithienamycin C is a carbapenem antibiotic. Epithienamycin C has anti-Gram-positive and Gram-negative bacteria activity .
|
-
- HY-N14436
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Pradimicin T1 is an antibiotic. Pradimicin Tl has activity against filamentous fungi and yeast-like fungi .
|
-
- HY-B0276S
-
|
2-ethylthioisonicotinamide-d3
|
Bacterial
Antibiotic
|
Infection
|
|
Ethionamide-d3 is the deuterium labeled Ethionamide. Ethionamide (2-ethylthioisonicotinamide) is an antibiotic used in the treatment of tuberculosis.
|
-
- HY-115367
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aldgamycin G is a macrolide antibiotic active against Gram-positive bacteria and can be isolated from Streptomyces avidinii .
|
-
- HY-N14703
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
2-Hydroxygentamicin B1 is a 3 aminoglycoside antibiotic with anti-Gram-positive and negative bacteria activity .
|
-
- HY-N0195
-
|
2-Nitroimidazole
|
Bacterial
Antibiotic
|
Infection
|
|
Azomycin (2-Nitroimidazole) is an antibiotic which can be active against aerobic Gram-positive and Gram-negative bacteria.
|
-
- HY-N14705
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
2-Hydroxygentamicin C2 is an antibiotic of the gentamicin group with anti-Gram-positive and negative bacteria activity .
|
-
- HY-130471
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Sannamycin C is an aminoglycoside antibiotic. Sannamycin C has weak antibacterial activity against Gram-positive bacteria .
|
-
- HY-121148
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Mutalomycin is a polyether antibiotic. Mutalomycin has anti-Gram-positive bacteria, anti-mycoplasma and anti-coccidial activity .
|
-
- HY-N14653
-
|
|
Bacterial
|
Infection
|
|
Glysperin A has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .
|
-
- HY-107328
-
-
- HY-13725A
-
-
- HY-N7123
-
-
- HY-113569
-
|
L-Armentomycin
|
Antibiotic
Bacterial
|
Infection
|
|
Armentomycin (L-Armentomycin) is a nonprotein amino acid with antibiotic properties. Armentomycin mainly acts against Gram-negative bacteria .
|
-
- HY-N14174
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Epithienamycin A is a carbapenem antibiotic. Epithienamycin A has anti-Gram-positive bacteria and anti-Gram-negative bacteria activity .
|
-
- HY-133060
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Sannamycin B is an aminoglycoside antibiotic. Sannamycin B has only weak antibacterial activity against a few bacteria .
|
-
- HY-126708
-
|
|
ADC Cytotoxin
Antibiotic
|
Infection
|
|
Luisol A, an aromatic tetraol, is a major metabolite of an estuarine marine actinomycete of the genus Streptomyces. Luisol A, is an anthraquinone antibiotic analog .
|
-
- HY-B0269S
-
|
DL 473-d9; Cyclopentylrifampicin-d9
|
Bacterial
Antibiotic
|
Infection
|
|
Rifapentine-d9 is the deuterium labeled Rifapentine. Rifapentine (DL 473) is an antibiotic compound used in the treatment of tuberculosis.
|
-
- HY-113735
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cephapirin Benzathine is the benzathine salt form of cephapirin. Cephapirin Benzathine is the first generation cephalosporin with broad spectrum antibiotic activity .
|
-
- HY-B2077
-
|
Tuberactinomycin N
|
Bacterial
Antibiotic
|
Infection
|
|
Enviomycin (Tuberactinomycin N) is a antibacterial antibiotic. Enviomycin has been used to research chronic cavitary pulmonary tuberculosis .
|
-
- HY-N13951
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Aranochlor A is an antibiotic found in Pseudoarachniotus roseus (HIL Y-30499). Aranochlor A exhibits antibacterial and antifungal activities .
|
-
- HY-121922
-
|
Dibromoverongiaquinol
|
Bacterial
|
Infection
|
|
Dienone B is a marine algicide with antibiotic activity against both Gram-positive and Gram-negative marine bacteria .
|
-
- HY-B1743S
-
-
- HY-A0269
-
|
Amdinocillin; FL 1060
|
Bacterial
Antibiotic
|
Infection
|
|
Mecillinam (Amdinocillin), the β-lactam antibiotic, has a broad spectrum of activity against gram-negative organisms .
|
-
- HY-107769
-
-
- HY-172447
-
-
- HY-139628
-
|
|
Bacterial
|
Infection
Cancer
|
|
JPD447, a MAC-0547630 derivative, is a novel class of UppS inhibitor to potentiate β-lactam antibiotics.
|
-
- HY-18982R
-
|
Flagecidin (Standard); Wuningmeisu C (Standard)
|
DNA/RNA Synthesis
JNK
Bacterial
Apoptosis
Antibiotic
Parasite
|
Infection
Cancer
|
|
Anisomycin (Standard) is the analytical standard of Anisomycin. This product is intended for research and analytical applications. Anisomycin is a potent protein synthesis inhibitor which interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system[1]. Anisomycin is a JNK activator, which increases phospho-JNK[2][3]. Anisomycin is a bacterial antibiotic[4].
|
-
- HY-B0507R
-
|
|
Antibiotic
Bacterial
|
Endocrinology
Cancer
|
|
Sulfathiazole (Standard) is the analytical standard of Sulfathiazole (HY-B0507). This product is intended for research and analytical applications. Sulfathiazole is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRN expression of CYP17, CYP19, and 3β-HSD. Sulfathiazole increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish .
|
-
- HY-117869
-
-
- HY-136443R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
4-Epitetracycline (hydrochloride) (Standard) is the analytical standard of 4-Epitetracycline (hydrochloride). This product is intended for research and analytical applications. 4-Epitetracycline hydrochloride is a reversible epimer of Tetracycline (HY-A0107) that can be interconverted in nature. 4-Epitetracycline hydrochloride exhibits antibacterial activity .
|
-
- HY-B1592
-
|
|
Bacterial
|
Infection
|
|
Carbomycin is a peptidyl transferase inhibitor with an inhibition rate of 95% at 200 μM .
|
-
- HY-120658
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
(Rac)-LY193239 is a racemic modification of LY193239 (HY-120658A). LY193239 is a higher-lactam pyrazolidinone antibacterial agent .
|
-
- HY-18999R
-
|
|
Antibiotic
|
Infection
|
|
4-epi-Chlortetracycline (hydrochloride) (Standard) is the analytical standard of 4-epi-Chlortetracycline (hydrochloride). This product is intended for research and analytical applications. 4-epi-Chlortetracycline hydrochloride is an epimetabolite of Chlortetracycline hydrochloride. Chlortetracycline hydrochloride is an orally active, potent and selective inhibitor of methanogenic bacteria with bactericidal effect .
|
-
- HY-136443
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
4-Epitetracycline hydrochloride is a reversible epimer of Tetracycline (HY-A0107) that can be interconverted in nature. 4-Epitetracycline hydrochloride exhibits antibacterial activity .
|
-
- HY-B0507
-
|
|
Antibiotic
Bacterial
|
Endocrinology
Cancer
|
|
Sulfathiazole is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRN expression of CYP17, CYP19, and 3β-HSD. Sulfathiazole increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish .
|
-
- HY-127019R
-
-
- HY-157027
-
|
|
Fungal
|
Others
|
|
Antifungal agent 85 (compound 24f) is a potent antibacterial compound with the minimum inhibitory concentration (MIC) values between 2.5 and 10 μM against various Gram-positive bacteria .
|
-
- HY-18999
-
|
|
Antibiotic
|
Infection
|
|
4-epi-Chlortetracycline hydrochloride is an epimetabolite of Chlortetracycline hydrochloride. Chlortetracycline hydrochloride is an orally active, potent and selective inhibitor of methanogenic bacteria with bactericidal effect .
|
-
- HY-113560
-
-
- HY-P5571
-
-
- HY-W399439
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aurantiogliocladin is a weak antibiotic which was active against Staphylococcus epidermidis but not S. aureus. Aurantiogliocladin could inhibit biofilm formation .
|
-
- HY-N14410
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Clecarmycin C is an antitumor antibiotic. Clecarmycin C shows cytotoxicity and antitumor activity. Clecarmycin C shows antimicrobial activity .
|
-
- HY-B1244
-
|
1,2-Dimethyl-5-nitroimidazole
|
Parasite
Antibiotic
|
Infection
|
|
Dmetridazole (1,2-Dimethyl-5-nitroimidazole), a nitroimidazole-based antibiotic, combats protozoan infections .
|
-
- HY-N14437
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Pradimicin T2 is an antibiotic. Pradimicin T2 has activity against filamentous fungi and yeast-like fungi .
|
-
- HY-129673
-
-
- HY-N14416
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Parvodicin A is a glycopeptide antibiotic. Parvodicin A has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and Enterococcus faecalis .
|
-
- HY-W739149
-
-
- HY-B1275
-
|
Cefalotin sodium
|
Bacterial
Antibiotic
|
Infection
|
|
Cephalothin sodium is a first generation cephem antibiotic with a wide range antibacterial activity, is active against gram-positive and gram-negative bacteria.
|
-
- HY-N6784
-
-
- HY-N14248
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Melithiazol A is an antibiotic. Melithiazole A is a β-methoxyacrylate (MOA) inhibitor with strong anti-agent activity. Antifungal and cytotoxic agent .
|
-
- HY-N14768
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
O-Demethylpaulomycin A is an antibiotic with antibacterial activity. O-Demethylpaulomycin A can inhibit Gram-positive bacteria, especially Staphylococcus aureus .
|
-
- HY-109125A
-
|
SPA-S-753; SPA-S-752 L-aspartate
|
Antibiotic
Fungal
|
Infection
|
|
Amcipatricin diaspartate (SPA-S-753) is a semi-synthetic polyene antibiotic, with potent broad-spectrum antifungal activity .
|
-
- HY-129493
-
-
- HY-126813
-
|
|
Fungal
|
Infection
|
|
Concanamycin C inhibits proliferation of mouse splenic lymphocytes. Concanamycin C exhibits antibiotic effects against fungal and yeast .
|
-
- HY-N15075
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Espinomycin A2 is a sixteen-membered macrolide antibiotic. Espinomycin A2 is active against Gram-positive bacteria .
|
-
- HY-B0458A
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cefprozil is a second-generation cephalosporin type antibiotic. Cefprozil exhibits broad-spectrum antibacterial activity, and is orally active .
|
-
- HY-N13259
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Fluopsin C is a copper-containing antibiotic with strong anti-Gram-positive and negative bacteria activity and anti-tumor activity .
|
-
- HY-N14680
-
|
|
Bacterial
|
Infection
|
|
Glysperin C has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .
|
-
- HY-N14145
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Collinone is a recombinant angular polyketide antibiotic. Collinone shows antibacterial activities for gram-positive bacterial. Collinone shows cytotoxicity .
|
-
- HY-N13892
-
-
- HY-N13884
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Amythiamicin D is a thiopeptide antibiotic that inhibits the growth of many Gram-positive bacteria, but not Gram-negative bacteria such as E.coli .
|
-
- HY-B0526
-
-
- HY-B0458
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cefprozil monohydrate is a second-generation cephalosporin type antibiotic. Cefprozil monohydrate exhibits broad-spectrum antibacterial activity, and is orally active .
|
-
- HY-122302
-
|
|
Antibiotic
|
Others
|
|
BU-2313 A is a compound with antimicrobial activity, whose structure was determined to be a dienoyltetraamide acid-containing antibiotic related to streptolysin and tilamycin.
|
-
- HY-111521
-
|
Carbavance
|
Antibiotic
Bacterial
|
Infection
|
|
Meropenem-vaborbactam is an antibiotic against nonfermenting Gram-negative clinical isolates, including Enterobacteriaceae isolates with resistant and carbapenemase genotypes .
|
-
- HY-Z8447
-
|
|
Drug Metabolite
|
Infection
|
|
(9E)-Erythromycin A oxime is a metabolite of Roxithromycin (HY-B0435). Roxithromycin is a semi-synthetic macrolide antibiotic.
|
-
- HY-B1244S
-
|
1,2-Dimethyl-5-nitroimidazole-d3
|
Parasite
Antibiotic
|
Infection
|
|
Dimetridazole-d3 is a deuterium labeled Dimetridazole. Dmetridazole, a nitroimidazole-based antibiotic, combats protozoan infections[1].
|
-
- HY-N14674
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Permetin A is a peptide antibiotic. Permetin A has anti-Gram-negative bacteria, Gram-positive bacteria and anaerobic bacteria activity .
|
-
- HY-N14334
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Halomicin B is an ansamycin antibiotic. Halomicin B has activity against Gram-positive and Gram-negative bacteria (individual) .
|
-
- HY-N14338
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Sannamycin L is an aminoglycoside antibiotic. Sannamycin L has weak antibacterial activity against Gram-positive bacteria and Gram-negative bacteria .
|
-
- HY-B1374
-
-
- HY-118797
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Malioxamycin is an antibiotic that inhibits Gram-negative bacteria by inhibiting peptidoglycan synthesis in bacterial cell walls and promoting the formation of spheroplasts .
|
-
- HY-B0318S1
-
-
- HY-122334
-
|
|
Antibiotic
|
Infection
|
|
Myxopyronin A is an antibiotic that can be found in culture supernatant of the gliding bacterium Myxococcus fulvus strain Mx f50 (Myxobacterales) .
|
-
- HY-B0755
-
|
|
Antibiotic
|
Infection
|
|
Etimicin (sulfate), a fourth-generation aminoglycoside antibiotic, is now widely clinically used due to its high efficacy and low toxicity.
|
-
- HY-129291
-
|
AM 6201
|
Antibiotic
Bacterial
Fungal
|
Infection
Cancer
|
|
Reductiomycin is an antibiotic, which exhibits antimicrobial activity against gram positive bacteria and fungi. Reductiomycin exhibits antitumor activity .
|
-
- HY-W055872
-
|
|
Antibiotic
|
Infection
|
|
Erythromycylamine is a macrolide antibiotic. Erythromycylamine has antibacterial activity against most Gram-positive cocci and M. catarrhalis .
|
-
- HY-120185
-
|
UCT-1003
|
Topoisomerase
|
Infection
Cancer
|
|
Saintopin is an antitumor antibiotic. Saintopin is also an inhibitor of DNA topoisomerases I and II. Saintopin induces DNA cleavage .
|
-
- HY-151567
-
|
|
Bacterial
|
Infection
|
|
Antibacterial agent 123 (compound 111) is a potent membrane-disrupting agent to combat antibiotic-resistant Gram-positive bacteria .
|
-
- HY-N15032
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Espinomycin A3 is a sixteen-membered macrolide antibiotic. Espinomycin A3 is active against Gram-positive bacteria .
|
-
- HY-N14335
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Halomicin C is an ansamycin antibiotic. Halomicin C has activity against Gram-positive and Gram-negative bacteria (individual) .
|
-
- HY-123339
-
|
Istamycin X0; IST-X0
|
Antibiotic
Bacterial
|
Infection
|
|
Sannamycin G (Istamycin X0) is an aminoglycoside antibiotic and has only weak antibacterial activity against a few bacteria .
|
-
- HY-N14327
-
|
|
Bacterial
|
Infection
|
|
Ferensimycin B is a polyether antibiotic with anti-Gram-positive bacteria and weak anti-Gram-negative bacteria, fungi and coccidia .
|
-
- HY-N14654
-
|
|
Bacterial
|
Infection
|
|
Glysperin B has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .
|
-
- HY-137064
-
|
|
iGluR
|
Neurological Disease
|
|
Memantine lactose adduct is a lactose adduct of Memantine (HY-B0591) and an intermediate in the synthesis of adamantane amine antibiotics .
|
-
- HY-117074
-
-
- HY-N7218
-
-
- HY-131557
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
O-Deacetylravidomycin, a microbial metabolite discovered in Streptomyces, is an antibiotic. O-Deacetylravidomycin exhibits light-dependent antibacterial and anticancer activities .
|
-
- HY-N14247
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Exfoliazone is a phenoxazine antibiotic. Exfoliazone has the activity of resisting Valsa ceratosperma, and the ED50 that inhibits mycelial growth is 70 μg/mL .
|
-
- HY-A0279
-
|
Pristinamycine
|
Bacterial
Antibiotic
|
Infection
|
|
Pristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin-like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant S. aureus (VRSA) and Enterococcus faecium (VREF) .
|
-
- HY-10394S1
-
|
PNU-100766-d8
|
Antibiotic
Bacterial
Isotope-Labeled Compounds
|
Infection
|
|
PNU-100766-d8 is deuterated labeled Linezolid (HY-10394). Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics .
|
-
- HY-149333
-
|
|
Bacterial
|
Infection
|
|
BO-1 is a benzoate ester with antibacterial activity. BO-1 inhibits multidrug-resistant Staphylococcus aureus, and acts function synergistically with antibiotic, such as Ciprofloxacin (HY-B0356). BO-1 can reverse the resistance of antibiotic-resistant S. aureus strains, and decreases the level of inflammatory factors IL-6 and C-reactive protein in vivo in mice .
|
-
- HY-B0343BS
-
|
A-56620-d8 hydrochloride trihydrate
|
Bacterial
|
Inflammation/Immunology
|
|
Sarafloxacin-d8 (hydrochloride trihydrate) is the deuterium labeled Sarafloxacin hydrochloride trihydrate. Sarafloxacin hydrochloride trihydrate is a quinolone antibiotic compound[1][2].
|
-
- HY-N7242
-
|
|
Antibiotic
|
Infection
|
|
Plicacetin is a crystalline antibiotic isolated from the fermentation broth of Streptomyces actinomycetes and is structurally similar to Amicetin (HY-120383) and Bamicetin. .
|
-
- HY-N14905
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
α-Prumycin hydrochloride is a carbohydrate antibiotic. α-Prumycin hydrochloride has anti-fungal activity and weak anti-individual bacterial activity.
|
-
- HY-B2094
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Arbekacin, an aminoglycoside antibiotic, exhibits broad antimicrobial activities against not only Gram-positive bacteria but also Gram-negative bacteria .
|
-
- HY-N14829
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Naphthoquinomycin A is an Ansa antibiotic with anti-Gram-positive bacteria and fungi activity, and can inhibit the synthesis of E. coli fatty acids .
|
-
- HY-101411R
-
|
|
GABA Receptor
Endogenous Metabolite
Bacterial
|
Others
|
|
Josamycin propionate (Standard) is the analytical standard of Josamycin propionate. This product is intended for research and analytical applications. Josamycin propionate is classified as a macrolide antibiotic.
|
-
- HY-139106
-
|
|
Antibiotic
|
Others
|
|
N-Demethylansamitocin P-3 can be prepared from Ansamitocin (an antitumor ansamycin antibiotic) by Streptomyces minutiscleroticus IFO 13361 .
|
-
- HY-N13905
-
-
- HY-125561R
-
|
|
Antibiotic
|
Others
|
|
Josamycin propionate (Standard) is the analytical standard of Josamycin propionate. This product is intended for research and analytical applications. Josamycin propionate is classified as a macrolide antibiotic.
|
-
- HY-105165A
-
|
BBR 3438
|
Antibiotic
|
Cancer
|
|
Nortopixantrone dihydrochloride (BBR 3438) is a 9-aza-anthrapyrazole-based antineoplastic antibiotic. Nortopixantrone dihydrochloride plays an important role in cacner research .
|
-
- HY-B1222
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria.
|
-
- HY-N14250
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Melithiazol C is an antibiotic. Melithiazole C is a β-methoxyacrylate (MOA) inhibitor with strong anti-agent activity. Antifungal agent .
|
-
- HY-100180
-
|
LCB01-0371
|
Bacterial
Antibiotic
|
Infection
|
|
Delpazolid is a novel oxazolidinone antibiotic agent which can inhibit the growth of MSSA and MRSA with a MIC90 of 2 μg/mL for both of them.
|
-
- HY-N13961
-
|
XK-88-2
|
Antibiotic
Bacterial
|
Infection
|
|
Seldomycin factor 2 (XK 88-2) is an aminoglycoside antibiotic. Seldomycin factor 2 has a broad spectrum of antimicrobial activity .
|
-
- HY-142124
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Kalimantacin A is a potent antibiotic. Kalimantacin A shows antibacterial activity against staphylococcus including methicillin-resistant staphylococcus aureus (MRSA) .
|
-
- HY-130995
-
|
|
Antibiotic
ADC Cytotoxin
|
Infection
|
|
Agrochelin, an alkaloid cytotoxic antibiotic, is produced by the fermentation of a marine Agrobacterium sp. Agrochelin has cytotoxic activity in tumor cell lines .
|
-
- HY-N14209
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Epithienamycin D is a carbapenem antibiotic. Epithienamycin D has anti-Gram-positive bacteria and anti-Gram-negative bacteria activity .
|
-
- HY-B1743AS
-
|
CL13900-d3 dihydrochloride
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Puromycin-d3 (dihydrochloride) is the deuterium labeled Puromycin dihydrochloride. Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis[1].
|
-
- HY-N14301
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Aquayamycin is an angucycline antibiotic. Aquayamycin is active against Gram-positive bacteria, Ehrlich ascites carcinoma, and Yoshida rat sarcoma cells .
|
-
- HY-124138
-
|
Albomycetin; Amaromycin
|
Antibiotic
Bacterial
|
Infection
|
|
Pikromycin is a macrolide antibiotic that has been found in S. venezuelae and active against E. coli, S. aureus and B. subtilis .
|
-
- HY-N13964
-
|
XK 88-3
|
Antibiotic
Bacterial
|
Infection
|
|
Seldomycin factor 3 (XK 88-3) is an aminoglycoside antibiotic. Seldomycin factor 3 has a broad spectrum of antimicrobial activity .
|
-
- HY-W698254
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Fluopsin F is an antibiotic containing metallic iron with strong anti-Gram-positive and negative bacteria activity and anti-tumor activity .
|
-
- HY-N13920
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Avilamycin C is an avilamycin-type antibiotic. Avilamycin C has antibacterial activity and can inhibit Gram-positive bacteria .
|
-
- HY-A0071R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Tildipirosin (Standard) is the analytical standard of Tildipirosin. This product is intended for research and analytical applications. Tildipirosin, a long-acting macrolide, has antibiotic activity.
|
-
- HY-N14210
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Epithienamycin F is a carbapenem antibiotic. Epithienamycin F has anti-Gram-positive bacteria and anti-Gram-negative bacteria activity .
|
-
- HY-B0356S
-
|
Bay-09867-d8 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Ciprofloxacin-d8 (hydrochloride) is the deuterium labeled Ciprofloxacin. Ciprofloxacin (Bay-09867) hydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
|
-
- HY-108881
-
-
- HY-18258
-
-
- HY-N14859
-
-
- HY-121004
-
|
Lycopersin
|
Fungal
Antibiotic
|
Infection
|
|
Bikaverin (Lycopersin) is a reddish pigment produced by different fungal species. Bikaverin shows antibiotic properties against certain protozoa and fungi .
|
-
- HY-N14587
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Oxypyrrolnitrin is a nitrogen-containing heterocyclic antibiotic. Oxypyrrolnitrin has anti-Gram-positive bacteria, negative bacteria, mycobacterium and fungal effects .
|
-
- HY-124035
-
|
SF2583A
|
Antibiotic
Parasite
|
Infection
|
|
Streptochlorin (SF2583A) is an antibiotic. Streptochlorin has antitrypanosomal activity with an IC50 value of 230 ng/ml for GUTat 3.1 .
|
-
- HY-N13986
-
|
XX-88-5
|
Antibiotic
Bacterial
|
Infection
|
|
Seldomycin factor 5 (XK 88-5) is an aminoglycoside antibiotic. Seldomycin factor 5 has a broad spectrum of antimicrobial activity .
|
-
- HY-N13959
-
|
XK 88-1
|
Antibiotic
Bacterial
|
Infection
|
|
Seldomycin factor 1 (XK 88-1) is an aminoglycoside antibiotic. Seldomycin factor 1 has a broad spectrum of antimicrobial activity .
|
-
- HY-A0076
-
|
LJC 11036
|
Bacterial
Antibiotic
|
Infection
|
|
Tebipenem is an orally available carbapenem antibiotic, shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa.
|
-
- HY-B0356S1
-
|
Bay-09867-d8
|
Bacterial
Antibiotic
|
Infection
|
|
Ciprofloxacin-d8 is the deuterium labeled Ciprofloxacin. Ciprofloxacin (Bay-09867) is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
|
-
- HY-N14912
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
β-Prumycin hydrochloride is a carbohydrate antibiotic. β-Prumycin hydrochloride has anti-fungal activity and weak anti-individual bacterial activity.
|
-
- HY-B0239S
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Chloramphenicol-d5 is the deuterium labeled Chloramphenicol. Chloramphenicol is a broad-spectrum antibiotic against bacterial infections[1][2].
|
-
- HY-N5197
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Dapdiamide A is an antibiotic found in Pantoea agglomerans CU0119 strain, exhibiting antibacterial activity and potential applications in anti-infective research .
|
-
- HY-B0343AR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sarafloxacin (hydrochloride) (Standard) is the analytical standard of Sarafloxacin (hydrochloride). This product is intended for research and analytical applications. Sarafloxacin (hydrochloride) (A-56620 (hydrochloride)) is a quinolone antibiotic agent.
|
-
- HY-N14345
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Marcellomycin is a glycoside and quinone antibiotic. Marcellomycin has anti-Gram-positive bacteria effect, especially has strong effect on streptococcus .
|
-
- HY-N15368
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Pradimicinone I (Compound 10), a Pradimicin A (HY-132191) analog, is an antibiotic. Pradimicinone I is promising for research of antibacterial agents .
|
-
- HY-N8492
-
|
|
Antibiotic
|
Infection
|
|
Monascorubrin is purified from the mycelium of Monascus purpureus. Monascorubrin has significant antibiotic activities against Bacillus subtilis and Candida pseudotropicalis .
|
-
- HY-13588
-
|
SCE-129 sodium
|
Bacterial
Antibiotic
|
Infection
|
|
Cefsulodin (SCE-129) sodium is a third generation β lactam antibiotic and member of the cephems subgroup of antibiotics. Cefsulodin sodium inhibits cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) cross-linking and transpeptidation of peptidogly. Cefsulodin sodium is a potent tyrosine phosphatase inhibitor against mPTPB, a virulent phosphatase from Mycobacterium tuberculosis, with an IC50 value of 16 μM .
|
-
- HY-13588B
-
|
SCE-129 sodium hydrate
|
Antibiotic
Bacterial
|
Infection
|
|
Cefsulodin (SCE-129) sodium is a third generation β lactam antibiotic and member of the cephems subgroup of antibiotics. Cefsulodin sodium inhibits cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) cross-linking and transpeptidation of peptidogly. Cefsulodin sodium is a potent tyrosine phosphatase inhibitor against mPTPB, a virulent phosphatase from Mycobacterium tuberculosis, with an IC50 value of 16 μM .
|
-
- HY-N14661
-
|
|
Bacterial
|
Infection
|
|
Granaticinic acid is a quinone antibiotic. Granaticinic acid can be found in Streptomyces thermoviolaceus NT1. Granaticinic acid has anti-gram-positive bacterial activity .
|
-
- HY-B1252B
-
-
- HY-N15038
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Haloquinone is a quinone antibiotic. Haloquinone has strong anti-bacterial activity on Halobacteria, and also has effects on Gram-positive bacteria and mycoplasma .
|
-
- HY-156074
-
|
|
Antibiotic
|
Infection
|
|
Erythromycin propionate is an antibiotic that may have some hepatotoxic properties. Erythromycin propionate has no significant side effects below 0.5 mM .
|
-
- HY-128916
-
|
|
Bacterial
|
Infection
|
|
dmDNA31 is a rifamycin-class antibiotic that inhibits bacterial DNA-dependent RNA polymerase with potent bactericidal activity against S. aureus .
|
-
- HY-14603
-
|
Iodochlorohydroxyquinoline
|
Fungal
Autophagy
Mitophagy
Antibiotic
Parasite
|
Infection
Cancer
|
|
Clioquinol (Iodochlorhydroxyquin) is a topical antifungal agent with anticancer activity. Clioquinol acts as an oral antimicrobial agent for the research of diarrhea and skin infections. Antibiotic .
|
-
- HY-N14249
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Melithiazol B is an antibiotic. Melithiazole B is a β-methoxyacrylate (MOA) inhibitor with strong anti-agent activity. Antifungal and cytotoxic agent .
|
-
- HY-B1174
-
|
Kanamycin B
|
Antibiotic
Bacterial
|
Infection
|
|
Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain .
|
-
- HY-N7120
-
|
PGP hydrate
|
Bacterial
Antibiotic
|
Infection
|
|
Penicillin G Procaine hydrate (PGP hydrate), a β-lactam antibiotic, is a crystalline complex produced by chemically combining penicillin G with procaine .
|
-
- HY-N8401
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Musellactone is a lactone that can be isolated from Musella lasiocarpa. Musellactone is an antibiotic, that exhibits antibacterial activity against Bacillus megaterium and Sarcina lutea .
|
-
- HY-148209
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Balhimycin is a glycopeptide antibiotic, found from the fermentation broth of a Amycolatopsis sp. Balhimycin shows anti-bacterial activity against staphylococci and anaerobes .
|
-
- HY-N14513
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Pyrrolomycin A is a pyrrole antibiotic. Pyrrolomycin A has anti-Gram-positive bacteria, anti-Gram-negative bacteria and anti-individual fungi activity .
|
-
- HY-N10081
-
-
- HY-B1743R
-
|
CL13900 (Standard)
|
Bacterial
Antibiotic
Parasite
|
Infection
|
|
Puromycin (Standard) is the analytical standard of Puromycin. This product is intended for research and analytical applications. Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.
|
-
- HY-B0925S
-
-
- HY-N14982
-
-
- HY-B0522A
-
|
D-(-)-α-Aminobenzylpenicillin sodium salt
|
Bacterial
Antibiotic
|
Infection
|
|
Ampicillin sodium (D-(-)-α-Aminobenzylpenicillin sodium salt) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .
|
-
- HY-N7141R
-
|
|
Parasite
Antibiotic
Bacterial
|
Infection
|
|
Spiramycin I (Standard) is the analytical standard of Spiramycin I. This product is intended for research and analytical applications. Spiramycin I is a macrolide antibiotic and antiparasitic .
|
-
- HY-17506R
-
|
|
Bacterial
Autophagy
Antibiotic
Parasite
|
Infection
Cancer
|
|
Azithromycin (Standard) is the analytical standard of Azithromycin. This product is intended for research and analytical applications. Azithromycin is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
|
-
- HY-B0269R
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Rifapentine (Standard) is the analytical standard of Rifapentine. This product is intended for research and analytical applications. Rifapentine (DL 473) is an antibiotic used in tuberculosis research .
|
-
- HY-136434
-
|
m-threo-Chloramphenicol
|
Antibiotic
|
Others
|
|
m-Chloramphenicol (m-threo-Chloramphenicol) is an impurity of Chloramphenicol. Chloramphenicol, a broad-spectrum antibiotic, acts as a potent inhibitor of bacterial protein biosynthesis .
|
-
- HY-N15062
-
|
|
Antibiotic
Fungal
|
Infection
|
|
2-Hydroxymethylclavam is a β-lactam antibiotic. 2-Hydroxymethylclavam has antifungal activity, especially for plant pathogenic fungi .
|
-
- HY-Z9100
-
|
|
Antibiotic
|
Infection
|
|
N-demethyl Promethazine hydrochloride is a metabolite of Phenothiazine (HY-Y0055). Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities.
|
-
- HY-N14396
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Sannamycin F is an aminoglycoside antibiotic. Sannamycin F has weak antibacterial activity against Gram-positive bacteria and Gram-negative bacteria .
|
-
- HY-N14840
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
1-Hydroxysulfurmycin A is an anthracycline antibiotic. 1-Hydroxysulfurmycin A has anti-Gram-positive bacteria and anti-tumor cell activity .
|
-
- HY-N7097
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sulbenicillin disodium is the disodium salt of Sulbenicillin. Sulbenicillin is a Penicillin antibiotic with antibacterial activity against a number of mucoid and non-mucoid strains of Pseudomonas aeruginosa .
|
-
- HY-A0110A
-
|
CTM-HE hydrochloride; SCE-2174 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Cefotiam hexetil hydrochloride (CTM-HE) is an oral third-generation cephalosporin, which is a proagent of cefotiam, but has no anti-bacterial property. Cefotiam is an antibiotic .
|
-
- HY-Y0055
-
-
- HY-N14665
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Atrovenetin is an antibiotic found in Penicillium species. Atrovenetin has inhibitory activity against Bacillus subtilis and Staphylococcus aureus. Atrovenetin is also a potent antioxidant.
|
-
- HY-113795
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aldgamycin E is a neutral macrolide antibiotic that can be derived from culture filtrates of Streptomyces lavendulae. Aldgamycin E has antibacterial activity .
|
-
- HY-B0435R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Roxithromycin (Standard) is the analytical standard of Roxithromycin. This product is intended for research and analytical applications. Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic.
|
-
- HY-P2123A
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Colistin A sulfate hydrate is a major component of Colistin. Colistin is a polymyxin antibiotic and can be used to combat infections caused by problematic gram-negative bacteria .
|
-
- HY-N14380
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Sannamycin K is an aminoglycoside antibiotic. Sannamycin K has weak antibacterial activity against Gram-positive bacteria and Gram-negative bacteria .
|
-
- HY-N13885
-
|
|
Antibiotic
Bacterial
Parasite
|
Infection
|
|
Amythiamicin A is an antimicrobial antibiotic against Gram-positive bacteria (including methicillin-resistant Staphylococcus aureus (MRSA)) and activity against Plasmodium falciparum .
|
-
- HY-B0467AS
-
-
- HY-B1436
-
|
|
STAT
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Nifuroxazide is an effective inhibitor of STAT3, also exerts potent anti-tumor and anti-metastasis activity. Nifuroxazide is an orally active nitrofuran antibiotic.
|
-
- HY-N14849
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
1-Hydroxyauramycin A is an anthracycline antibiotic. 1-Hydroxyauramycin A has anti-Gram-positive bacteria and anti-tumor cell activity .
|
-
- HY-B0467S
-
-
- HY-16472
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Sulfacytine is a short-acting sulfonamide antibiotic. Sulfacytine is active against bacteria and is an effective agent for the research of acute uncomplicated urinary tract infections .
|
-
- HY-N14833
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Naphthoquinomycin B is an Ansa antibiotic with anti-Gram-positive bacteria and fungi activity, and can inhibit the synthesis of E. coli fatty acids .
|
-
- HY-151224R
-
|
|
DNA/RNA Synthesis
|
Others
|
|
Roxithromycin (Standard) is the analytical standard of Roxithromycin. This product is intended for research and analytical applications. Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic.
|
-
- HY-18257
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Rolitetracycline, a derivative of tetracycline, is a broad-spectrum antibiotic . Rolitetracyclin has a role as a protein synthesis inhibitor, an antiprotozoal agent and a proagent .
|
-
- HY-U00035
-
|
|
Bacterial
|
Infection
|
|
MGB-BP-3 is an antibiotic that has been shown to be active against a broad range of important multi-resistant Gram-positive pathogens.
|
-
- HY-N11415
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aurachin SS is a nature product that could be isolated from Streptomyces sp. NA04227. Aurachin SS is an antibiotic and has antibacterial activity .
|
-
- HY-17506AR
-
|
|
Bacterial
Autophagy
Antibiotic
Parasite
|
Infection
Cancer
|
|
Azithromycin (hydrate) (Standard) is the analytical standard of Azithromycin (hydrate). This product is intended for research and analytical applications. Azithromycin hydrate is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
|
-
- HY-N14972
-
-
- HY-N15106
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
11-Deoxy-13-deoxodaunorubicin is an anthracycline antibiotic with anti-Gram-positive bacteria, negative bacteria and tumor activity .
|
-
- HY-138194
-
|
A-16316-C
|
Antibiotic
Fungal
|
Infection
|
|
Destomycin B (A-16316-C) is an antibiotic, and is active against fungi. Destomycin B also has anthelmintic activity .
|
-
- HY-A0089
-
|
Polymyxin E sulfate
|
Bacterial
Autophagy
Antibiotic
|
Infection
|
|
Colistin sulfate is a polypeptide antibiotic which inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria.
|
-
- HY-13766A
-
|
VX-853-2
|
Bacterial
|
Others
|
|
Timcodar mesylate (VX-853-2) and its analog VX-710 are mammalian multidrug-resistant bacterial efflux pump inhibitors that directly inhibit ethidium bromide efflux in Staphylococcus aureus. Timcodar mesylate has the potential to enhance antibiotic activity by inhibiting bacterial efflux pumps, effectively reducing the minimum inhibitory concentration of some antibiotics against Gram-positive pathogens such as Staphylococcus aureus, Enterococcus and Streptococcus pneumoniae .
|
-
- HY-B1086
-
|
N-Acetyl-DL-phenylalanine
|
Endogenous Metabolite
|
Neurological Disease
|
|
Afalanine (N-Acetyl-DL-phenylalanine) is an endogenous metabolite of an endophytic fungus with antidepressant activity. Afalanine can be used in combination with antibiotics to prevent renal damage.
|
-
- HY-125388
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Martinomycin is an antibiotic, which inhibits Staphylococcus spp., Streptococcus spp. and Enterococcus spp., with MICs ranging from 0.06 to 0.5 μg/mL .
|
-
- HY-135212
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .
|
-
- HY-121136A
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Chartreusin sodium is an antibiotic that is active against certain Gram-positive organisms and mycobacteria. Chartreusin is also active against the Micrococcus fiyogenes v. aureus phage .
|
-
- HY-N14673
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Helvecardin A is a glycopeptidtic antibiotic. Helvecardin A has strong activity of anti-aerobic and anaerobic Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus .
|
-
- HY-B1894
-
|
Ro 15-8075 free base
|
Bacterial
Antibiotic
|
Infection
|
|
Cefetamet pivoxyl is a cephalosporin antibiotic. Cefetamet pivoxyl inhibits 355 enteropathogens Keime, Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila .
|
-
- HY-B1340
-
-
- HY-B0272
-
-
- HY-118021
-
|
YL-0358M-A
|
Antibiotic
|
Infection
|
|
Hatomamicin is an alkaloid antibiotic that can be isolated from the culture filtrate of Sucrose Polyspora. Hatomamicin exhibits antibacterial activity against Gram-positive bacteria .
|
-
- HY-B0276R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Ethionamide (Standard) is the analytical standard of Ethionamide. This product is intended for research and analytical applications. Ethionamide (2-ethylthioisonicotinamide) is a second-line anti-tuberculosis antibiotic.
|
-
- HY-125608
-
|
Lipiarmycin B3
|
Antibiotic
Bacterial
|
Infection
|
|
Tiacumicin C (Lipiarmycin B3) is an antibiotic with activity against Gram-positive bacteria. Tiacumicin C is employed in research related to bacterial infections .
|
-
- HY-N14485
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Nebramycin IV is an aminoglycoside antibiotic. Nebramycin IV has a broad antibacterial spectrum and has a strong effect on Gram-positive and negative bacteria and mycobacteria .
|
-
- HY-B1463R
-
|
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Penicillin G sodium salt (Standard) is the analytical standard of Penicillin G sodium salt. This product is intended for research and analytical applications. Penicillin G sodium salt is a typical β-lactam antibiotic.
|
-
- HY-128459R
-
|
|
Drug Metabolite
|
Others
|
|
N-Demethylerythromycin A (Standard) is the analytical standard of N-Demethylerythromycin A. This product is intended for research and analytical applications. N-Demethylerythromycin A is a metabolite of Erythromycin A. Erythromycin A is an antibiotic .
|
-
- HY-N13906
-
-
- HY-B0875B
-
|
SCE-1365 sodium
|
Antibiotic
Bacterial
|
Infection
|
|
Cefmenoxime sodium is a new semisynthetic cephalosporin antibiotic. Cefmenoxime sodium has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .
|
-
- HY-N14697
-
|
|
Antibiotic
|
Cancer
|
|
Cytorhodin X is a cytotoxic antibiotic. Cytorhodin X can inhibit the proliferation of L1210 murine leukemia cells, with an ED50 of 0.36 μM .
|
-
- HY-P1720
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Telomycin is a calcium-dependent antibiotic, which can be produced by Streptomyces. Telomycin inhibits gram-positive bacteria, including multidrug-resistant (MDR) pathogens .
|
-
- HY-N14974
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Ericamycin is an antibiotic that exhibits antibacterial activity against Gram-positive activity, inhibits Staphylococcus aureus with MIC of 0.004-0.016 µg/mL .
|
-
- HY-B1743AR
-
|
|
Bacterial
Antibiotic
Parasite
|
Infection
|
|
Puromycin (dihydrochloride) (Standard) is the analytical standard of Puromycin (dihydrochloride). This product is intended for research and analytical applications. Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis .
|
-
- HY-B0522B
-
|
D-(-)-α-Aminobenzylpenicillin trihydrate
|
Bacterial
Antibiotic
|
Infection
|
|
Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.
|
-
- HY-N10617
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Hygromycin A is a Borrelia burgdorferi-selective antibiotic. Hygromycin A is a spirochete-specific antibacterial that is conducive to gut health. Hygromycin A can be used for Lyme disease research .
|
-
- HY-108279
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Ulifloxacin is a broad-spectrum quinolone antibiotic. Ulifloxacin is the active metabolite of Prulifloxacin (HY-B0024). Ulifloxacin has anti-bacterial activity .
|
-
- HY-105165
-
|
BBR 3438 free base
|
Antibiotic
|
Cancer
|
|
Nortopixantrone (BBR 3438 free base) is a 9-aza-anthrapyrazole-based antineoplastic antibiotic. Nortopixantrone plays an important role in cacner research .
|
-
- HY-P0274
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
PGLa, a 21-residue peptide, is an antimicrobial peptide. PGLa is a member of the magainin family of antibiotic peptides found in frog skin and its secretions .
|
-
- HY-W190927
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
MC-Val-Cit-Doxorubicin is drug-linker conjugate for ADC. The maleimide can conjugate with thiol containing molecules. Doxorubicin is an anthracycline antibiotic with antineoplastic activity
|
-
- HY-N13881
-
|
|
Antibiotic
Bacterial
Parasite
|
Infection
|
|
Amythiamicin C is an antimicrobial antibiotic against Gram-positive bacteria (including methicillin-resistant Staphylococcus aureus (MRSA)) and activity against Plasmodium falciparum .
|
-
- HY-121136
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Chartreusin is an antibiotic that is active against certain Gram-positive organisms and mycobacteria. Chartreusin is also active against the Micrococcus fiyogenes v. aureus phage .
|
-
- HY-B0472R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Streptomycin (sulfate) (Standard) is the analytical standard of Streptomycin (sulfate). This product is intended for research and analytical applications. Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.
|
-
- HY-W129471R
-
|
|
Bacterial
|
Others
|
|
Streptomycin (sulfate) (Standard) is the analytical standard of Streptomycin (sulfate). This product is intended for research and analytical applications. Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.
|
-
- HY-W076898A
-
|
|
Antibiotic
|
Others
|
|
Hydroxyethyl disulfide blocks the inhibitory effect of showdomycin on methotrexate-resistant thymidylate synthase and is also protected by its substrate deoxyuridylic acid, preventing inactivation of the antibiotic .
|
-
- HY-N14973
-
|
|
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Epoxyquinomicin D is an antibiotic that can be isolated from Amycolatopsis sp. Epoxyquinomicin D exhibits anti-inflammatory effects against collagen-induced arthritis .
|
-
- HY-167644
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cefoxazole is a β-lactam antibiotic containing an isoxazole moiety and exhibits antibacterial activity. Cefoxazole can be used in studies related to infectious diseases .
|
-
- HY-126818
-
-
- HY-107833
-
|
|
Bacterial
|
Infection
|
|
A40926, the precursor of Dalbavancin, is a second-generation glycopeptide antibiotic. A40926 inhibits gram-positive bacteria, and is very active against Neisseria gonorrhoeae .
|
-
- HY-148286
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Gentamicin C1a is the precursor of the semi-synthetic antibiotic Etimicin, and has antibacterial activity. Gentamicin C1a is the major component of the Gentamicin complex .
|
-
- HY-117180
-
|
30-Hydroxy-naphthomycin C
|
Antibiotic
|
Infection
Cancer
|
|
Diastovaricin I (30-Hydroxy-naphthomycin C) is an antibiotic without exhibiting antimicrobial activity. Diastovaricin I induces differentation of mouse Friend cell .
|
-
- HY-N14860
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Milbemycin β3 is a macrolide antibiotic. Milbemycin β3 has insecticidal effects on agricultural harmful insects, pans, larvae, etc .
|
-
- HY-N14847
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
1-Hydroxyauramycin B is an anthracycline antibiotic. 1-Hydroxyauramycin B has anti-Gram-positive bacteria and anti-tumor cell activity .
|
-
- HY-B0337R
-
|
Sulphadimethoxine (Standard)
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfadimethoxine (Standard) is the analytical standard of Sulfadimethoxine. This product is intended for research and analytical applications. Sulfadimethoxine (Sulphadimethoxine) is a sulfonamide antibiotic used to treat many infections .
|
-
- HY-N15035
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Bis(N-methylthioformohydroxamate)nickel (II) is an antibiotic containing metallic nickel with strong anti-Gram-positive and negative bacteria activity and anti-tumor activity .
|
-
- HY-126740
-
|
|
Antibiotic
Fungal
|
Infection
Cancer
|
|
Anguinomycin A is an antibiotic that exhibits good inhibitory activity against G. boninense with an MIC value of 5 µg/disk. Anguinomycin A has antitumor activity .
|
-
- HY-125512
-
|
|
Antibiotic
|
Infection
|
|
Saccharocarcin B is a macrocyclic lactone antibiotic that is active against the Gram-positive bacteria M. luteus and S. aureus as well as the Gram-negative bacteria C. trachomatis.
|
-
- HY-129166
-
|
|
Bacterial
|
Infection
|
|
UCM53, a FtsZ inhibitor, is an antibacterial agent. UCM53 can inhibit the growth of clinical isolates of antibiotic-resistant Staphylococcus aureus and Enterococcus faecalis
|
-
- HY-117260
-
-
- HY-N14363
-
-
- HY-N10338
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Mildiomycin is a Streptoverticillium rimofaciens antibiotic against powdery mildew of barley. Mildiomycin inhibits some Mycobacterium and Rhodotorula growth, but fails against most fungi and bacteria .
|
-
- HY-N14623
-
|
|
Bacterial
|
Infection
|
|
Paulomycin B has anti-Gram-positive bacteria effect, and it has inhibitory effect on Staphylococcus aureus resistant to penicillin, Streptomycin, Neomycin and Macrolide antibiotics .
|
-
- HY-B1190S
-
|
BL-S 578-d4 hydrate
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Cefadroxil-d4 (hydrate) is the deuterium labeled Cefadroxil. Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.
|
-
- HY-B1369AS
-
|
N-Formimidoyl thienamycin-d4; MK0787-d4
|
Isotope-Labeled Compounds
|
Infection
|
|
Imipenem-d4 (N-Formimidoyl thienamycin-d4) is a deuterium labeled Imipenem (HY-B1369A). Imipenem is an antibiotic .
|
-
- HY-N15184
-
|
Pradimicin C
|
Bacterial
Fungal
|
Infection
|
|
Benanomicin B (Pradimicin C) is an antifungal antibiotic that also has antibacterial activity against two Gram-positive bacteria: Micrococcus luteus and Corynebacterium bovis .
|
-
- HY-B0502S
-
-
- HY-131144S
-
|
|
Antibiotic
|
Infection
|
|
AMOZ-d5 is a deuterium labeled AMOZ. AMOZ, a tissue bound metabolite of Furaltadone, Furaltadone is a synthetic nitrofuran antibiotic widely used[1].
|
-
- HY-N15128
-
-
- HY-N15066
-
-
- HY-119657
-
|
|
Bacterial
|
Others
|
|
Cellocidin is an agricultural antibiotic with preventive effects against rice bacterial leaf blight and is thought to work by inhibiting the α-ketoglutarate-succinate system in Xanthomonas sp.
|
-
- HY-B0132A
-
|
MK-0366 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Norfloxacin hydrochloride (MK-0366 hydrochloride) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.
|
-
- HY-B0337S2
-
-
- HY-119589
-
|
Dactylarin
|
Antibiotic
|
Others
|
|
Altersolanol B (Dactylarin), a compound isolated from fungi, is structurally related to antibiotics and has been shown to induce ATP catabolism in Ehrlich ascites tumor cells.
|
-
- HY-P10233
-
|
|
Bacterial
|
Infection
|
|
SAAP 148 is an antimicrobial and antibiofilm agent, and exhibits inhibitory efficacy against antibiotic-resistant pathogens, with LC50 of 0.8-12.8 μM .
|
-
- HY-B0465R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Oxacillin (sodium monohydrate) (Standard) is the analytical standard of Oxacillin (sodium monohydrate). This product is intended for research and analytical applications. Oxacillin sodium monohydrate is an antibiotic similar to Flucloxacillin used in resistant staphylococci infections study .
|
-
- HY-N15129
-
-
- HY-111525
-
|
|
Oxidative Phosphorylation
Bacterial
Antibiotic
|
Infection
|
|
Monactin is a mactrotetralide antibiotic and a non-selective ionophore for monovalent cations, including potassium, sodium, and lithium. Monactin is isolated from Streptomyces and has antiproliferative activity .
|
-
- HY-N14762
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Leucomycin V is a macrolide antibiotic. Leucomycin V has strong anti-Gram-positive bacterial effect, and also has an effect on spirochetes, Rickettsium and Chlamydia .
|
-
- HY-17626C
-
|
(R)-WCK-2349
|
Antibiotic
|
Others
|
|
(R)-Alalevonadifloxacin mesylate is an isomer of Alalevonadifloxacin mesylate (HY-17626B). Alalevonadifloxacin mesylate is a oraly active anti-methicillin-resistant Staphylococcus aureus (MRSA) antibiotic .
|
-
- HY-N14900
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Milbemycin β1 is a macrolide antibiotic. Milbemycin β1 has insecticidal effects on agricultural harmful insects, pans, larvae, etc .
|
-
- HY-B0132
-
-
- HY-17577
-
-
- HY-158977
-
|
|
Beta-lactamase
Bacterial
|
Infection
|
|
β-Lactamase-IN-9 (compound 2) is a β-lactamase inhibitor that can restore the sensitivity of pathogens to β-lactam antibiotics .
|
-
- HY-B0308S
-
-
- HY-N13919
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Avilamycin B is an orally active antibiotic that can be isolated from Streptomyces viridochomogenes. Avilamycin B can be used for the research of intestinal bacteria-related diseases .
|
-
- HY-N12421
-
|
Volonomycin A
|
Bacterial
|
Infection
|
|
Paulomycin A (Volonomycin A) has anti-Gram-positive bacteria effect, and it has inhibitory effect on Staphylococcus aureus resistant to penicillin, Streptomycin, Neomycin and Macrolide antibiotics .
|
-
- HY-W706112
-
-
- HY-106922A
-
|
GV104326 sodium
|
Antibiotic
Bacterial
|
Infection
|
|
Sanfetrinem (GV104326) sodium is a beta-lactamase-stable antibiotic. Sanfetrinem sodium has broad-spectrum activity against gram-positive and gram-negative bacteria .
|
-
- HY-16158
-
|
Wy-4508; Aminocyclohexylpenicillin; Ciclacillin
|
Bacterial
Antibiotic
|
Infection
|
|
Cyclacillin (Wy-4508) is an orally active aminopenicillin antibiotic, shows antibacterial activity against a wide range of gram-positive and gram-negative pathogens .
|
-
- HY-A0163D
-
|
(E)-Clopenthixol
|
Antibiotic
Bacterial
Parasite
|
Infection
|
|
trans-Clopenthixol ((E)-Clopenthixol) is an antibiotic, without neuroleptic effect. trans-Clopenthixol can be used to inhibit Pseudomonas aeruginosa and Plasmodium falciparum in vitro .
|
-
- HY-126140
-
|
|
Bacterial
|
Infection
|
|
MDRTB-IN-1 (5aα) is an antibiotic which is against Mycobacterium tuberculosis H37Rv with a MIC90 value of 10.5 μM .
|
-
- HY-136456
-
|
|
Drug Metabolite
|
Others
|
|
2-NP-AMOZ is a 2-nitrophenyl derivative of AMOZ (a metabolite of antibiotic Furaltadone), can be used to detect protein bound AMOZ .
|
-
- HY-N14616
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Reumycin is a 7-azapteridine antibiotic. Reumycin is toxic to Airy carcinoma, sarcoma-180, sarcoma-37, lymphosarcoma and other tumor cells .
|
-
- HY-N14583
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Glucoallosamidin A is a glycoside antibiotic that can inhibit Chitinase activity. Glucoallosamidin A can inhibit Candida albicans ATCC 10231 chitinase with an IC50 of 3.4 μg/mL .
|
-
- HY-136991
-
|
|
Antibiotic
|
Others
|
|
Basacv is a DNA-polyintercalating bifunctional compound with DNA-high affinity. Basacv is structurally analogous to the antibiotic anti-tumour drug Triostin A and act as a bis-intercalator .
|
-
- HY-N13877
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Arugomycin, an anthracycline natural product, is antibiotic against Gram-positive bacteria. Arugomycin has potential as an antitumor agent from its ability to intercalate DNA .
|
-
- HY-P5570
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Aurein 2.3 is an antibiotic antimicrobial peptide. Aurein 2.3 partially inhibits E.coli ATPase activity and inhibits cell growth .
|
-
- HY-W726164
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Gentamicin A is an antibiotic with good antibacterial activity to Gram-positive bacteria and negative bacteria. Gentamicin A has antibacterial activity against most methicillin-sensitive staphylococcus .
|
-
- HY-B0198S
-
-
- HY-N14532
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Pyrrolomycin E is a pyrrole antibiotic. Pyrrolomycin E has anti-Gram-positive bacteria, anti-Gram-negative bacteria and anti-individual fungi activity .
|
-
- HY-N14008
-
|
|
Antibiotic
Bacterial
Fungal
Parasite
|
Infection
|
|
Carriomycin is an antibiotic that can be isolated from Streptomyces hygroscopicus. Carriomycin can inhibit Gram-positive bacteria, mycobacteria, yeasts and fungi, and is also an effective anticoccidial agent .
|
-
- HY-B0506R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Nadifloxacin (Standard) is the analytical standard of Nadifloxacin. This product is intended for research and analytical applications. Nadifloxacin (OPC7251) is a broad-spectrum fluoroquinolone antibiotic that is effective against acne vulgaris.
|
-
- HY-106371
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Siccanin is a succinate dehydrogenase (SDH) inhibitor (IC50=0.9 μM) with species-selective activity. Siccanin also is a antibiotic against pathogenic fungi .
|
-
- HY-N15095
-
|
|
Antibiotic
Bacterial
Parasite
|
Infection
|
|
Aplasmomycin is a boron-containing macrodiolide antibiotic. Aplasmomycin shows antimicrobial activity against Gram-positive bacteria and exhibits inhibitory activity against plasmodium infections in vivo .
|
-
- HY-121349
-
|
|
Bacterial
Fungal
Antibiotic
|
Infection
Cancer
|
|
Aerothionin is an antibiotic with potent antimicrobial efficacy against bacteria and fungi. Aerothionin exhibits antitumor efficacy against adrenal pheochromocytomas and extra-adrenal paragangliomas (PPGLs) .
|
-
- HY-B0490R
-
|
|
Bacterial
Fungal
Antibiotic
Parasite
|
Infection
|
|
Hygromycin B (Standard) is the analytical standard of Hygromycin B. This product is intended for research and analytical applications. Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.
|
-
- HY-76260R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Faropenem sodium (Standard) is the analytical standard of Faropenem sodium. This product is intended for research and analytical applications. Faropenem sodium is an orally bioavailable penem antibiotic which can efficiently kill Mycobacterium tuberculosis.
|
-
- HY-126804
-
|
|
Antibiotic
|
Infection
Cancer
|
|
Safracin B, a tetrahydroisoquinoline (THIQ) alkaloid, is a naturally occurring antibiotic from Pseudomonas fluorescens. Safracin B exhibits broad spectrum antimicrobial and strong antitumor activities .
|
-
- HY-111264
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Naphthomycin B is an antibiotic, which is initially isolated from Streptomyces sp. Naphthomycin B exhibits antimicrobial activities against gram positive bacteria and many fungis .
|
-
- HY-N13981
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Arylomycin B2, an antibiotic, is a potent signal peptidase I (SPase I) inhibitor. Arylomycin B2 has anti-Gram-positive bacteria activities .
|
-
- HY-A0107S
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Tetracycline-d6 is the deuterium labeled Tetracycline. Tetracycline is a broad-spectrum antibiotic, exhibiting activity against a wide range of gram-positive and gram-negative bacteria.
|
-
- HY-N14999
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Decatromicin A is an antibiotic that can be isolated from Actinomadura MK73-NF4. Decatromicin A has anti-gram-positive bacterial activity .
|
-
- HY-A0246AR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Flucloxacillin sodium (Standard) is the analytical standard of Flucloxacillin sodium. This product is intended for research and analytical applications. Flucloxacillin sodium is an active antibiotic against gram-positive and gram-negative bacteria .
|
-
- HY-B0221A
-
-
- HY-N14657
-
|
|
Bacterial
|
Infection
|
|
Paulomycin A2 has anti-Gram-positive bacteria effect, and it has inhibitory effect on Staphylococcus aureus resistant to penicillin, Streptomycin, Neomycin and Macrolide antibiotics .
|
-
- HY-108877
-
|
BMY-28142 hydrochloride
|
Antibiotic
Bacterial
|
Infection
|
|
Cefepime hydrochloride is a cephalosporin antibiotic agent. Cefepime hydrochloride has inhibitory activity against human serum paraoxonase-1 (hPON1) with an IC50 value of 21.115 mM .
|
-
- HY-N15086
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Leucomycin U is a macrolide antibiotic. Leucomycin A9 has strong anti-Gram-positive bacterial effect, and also has an effect on spirochetes, Rickettsium and Chlamydia .
|
-
- HY-136428S
-
|
|
Isotope-Labeled Compounds
|
Cancer
|
|
Desoxycarbadox-d3 is the deuterium labeled Desoxycarbadox. Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound.
|
-
- HY-106597A
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Pirlimycin hydrochloride, a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin hydrochloride acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome .
|
-
- HY-N14491
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Coumamidine γ2 is a kind of alkaline sugar Cinodine antibiotic, which has broad spectrum antibacterial activity and also has effect on pseudomonas aeruginosa .
|
-
- HY-108569
-
|
|
Antibiotic
Bacterial
PPAR
|
Infection
|
|
nTZDpa is an antibiotic. nTZDpa is a PPARG partial agonist. nTZDpa has antibacterial activity. nTZDpa is effective against growing and persistent Staphylococcus aureus by lipid bilayer disruption .
|
-
- HY-19584
-
|
|
Fungal
|
Infection
|
|
Variotin is an Anti-Fungal Agent. Variotin has a strong antibiotic activity on dermatophytes such as Trichophyton, Microsporum, and Epidermophyton, and also pathogenic fungi in internal mycosis such as Blastomyces and Cryptococcus .
|
-
- HY-P0274A
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
PGLa TFA, a 21-residue peptide, is an antimicrobial peptide. PGLa TFA is a member of the magainin family of antibiotic peptides found in frog skin and its secretions .
|
-
- HY-N14675
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Helvecardin B is a glycopeptidtic antibiotic. Helvecardin B has strong activity of anti-aerobic and anaerobic Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus .
|
-
- HY-B0272S2
-
|
Rifampin-d4; Rifamycin AMP-d4
|
Bacterial
Influenza Virus
Antibiotic
|
Infection
|
|
Rifampicin-d4 is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.
|
-
- HY-17025S
-
|
Ansamycin-d7; LM-427-d7
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Rifabutin-d7 is the deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.
|
-
- HY-125653
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Kapurimycin A2 is an antitumor antibiotic that can be found in the culture of Streptomyces sp.. Kapurimycin A2 is an active against bacteria, particularly Gram-positive organisms .
|
-
- HY-126532
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Fmoc-Val-Cit-PAB-Duocarmycin TM is a agent-linker conjugate for ADC by using the antitumor antibiotic, Duocarmycin TM, linked via Fmoc-Val-Cit-PAB.
|
-
- HY-10394S
-
|
PNU-100766-d3
|
Bacterial
Antibiotic
|
Infection
|
|
Linezolid-d3 is a deuterium labeled Linezolid (PNU-100766). Linezolid is a synthetic antibiotic that acts by inhibiting the initiation of bacterial protein synthesis[1].
|
-
- HY-17506S
-
-
- HY-14881AR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Bedaquiline (fumarate) (Standard) is the analytical standard of Bedaquiline (fumarate). This product is intended for research and analytical applications. Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
|
-
- HY-138538
-
|
|
Antibiotic
|
Others
|
|
2-Nitrobenzaldehyde Semicarbazone is a derivative of Semicarbazide. 2-Nitrobenzaldehyde Semicarbazone can be measured as a metabolite marker to detect the widely banned antibiotic Nitrofurazone .
|
-
- HY-N6665R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefquinome (sulfate) (Standard) is the analytical standard of Cefquinome (sulfate). This product is intended for research and analytical applications. Cefquinome sulfate is a cephem antibiotic, which inhibits members of the Enterobacteriaceae .
|
-
- HY-P10233A
-
|
|
Bacterial
|
Infection
|
|
SAAP 148 TFA is an antimicrobial and antibiofilm agent, and exhibits inhibitory efficacy against antibiotic-resistant pathogens, with LC50 of 0.8-12.8 μM .
|
-
- HY-129307
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Gilvocarcin V is an antibiotic with antibacterial activity and can be isolated from Actinomycete. Gilvocarcin V also has anti-tumor activity and can be used in cancer research .
|
-
- HY-B1327S
-
|
7-Chlorotetracycline-d6 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Chlortetracycline-d6 (hydrochloride) is the deuterium labeled Chlortetracycline hydrochloride. Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is a specific and potent calcium ionophore antibiotic, inhibits binding of aminoacyl-tRNA to ribosomes.
|
-
- HY-B0318
-
-
- HY-N14582
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Glomosporin is a cyclic ester peptide antifungal antibiotic, and it has moderate anti-Aspergillus flavus (including Aspergillus Niger and Aspergillus Niger), yeast activity (MIC is 16 μg/mL) .
|
-
- HY-A0163C
-
|
(E)-Clopenthixol dihydrochloride
|
Antibiotic
Bacterial
Parasite
|
Infection
|
|
trans-Clopenthixol ((E)-Clopenthixol) dihydrochloride is an antibiotic agent, without neuroleptic effect. trans-Clopenthixol dihydrochloride can be used to inhibit Pseudomonas aeruginosa and Plasmodium falciparum in vitro .
|
-
- HY-N6739R
-
-
- HY-N14161
-
|
|
Thymidylate Synthase
Apoptosis
|
Cancer
|
|
Diazaquinomycin A (DAQA), a diaza-anthracene antibiotic, is a thymidylate synthase inhibitor. Diazaquinomycin A (DAQA) induces DNA damage, cell cycle arrest, and apoptosis through cleaved-PARP .
|
-
- HY-W008923R
-
|
|
MMP
Bacterial
Parasite
Antibiotic
|
Infection
Cancer
|
|
Doxycycline (monohydrate) (Standard) is the analytical standard of Doxycycline (monohydrate). This product is intended for research and analytical applications. Doxycycline monohydrate is an antibiotic and broad-spectrum metalloproteinase (MMP) inhibitor .
|
-
- HY-105180
-
|
BO-2727 free acid
|
Bacterial
|
Infection
|
|
Lenapenem (BO-2727 free acid), a carbapenem antibiotic, has potent antibacterial activity against Gram-positive and Gram-negative bacteria including P. aeruginosa .
|
-
- HY-105841A
-
|
M 139603
|
Antibiotic
|
Infection
|
|
Tetronasin (M 139603) sodium is a growth-promoting antibiotic with activity against Gram-positive bacteria. Tetronasin sodium is an oral activity that can be administered in the animal's food or water supply .
|
-
- HY-B0343AS
-
-
- HY-N9460
-
|
|
DNA Alkylator/Crosslinker
Antibiotic
|
Cancer
|
|
Sibiromycin is a naturally produced glycosylated pyrrolobenzodiazepines (PBDs). Sibiromycin is also a potent antitumor antibiotic that binds covalently to DNA in the minor groove at the NH2 of guanine .
|
-
- HY-N14475
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Sakyomicin B is a Benzoquinone antibiotic found in the strain of Nocardia sp. M-53. Sakyomicin B has activity against Gram-positive bacteria and mycobacteria .
|
-
- HY-106597
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Pirlimycin, a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome .
|
-
- HY-W013266
-
|
Acetylsulfamethoxazole
|
Bacterial
|
Infection
Metabolic Disease
|
|
N4-Acetylsulfamethoxazole (Acetylsulfamethoxazole) is a metabolite of Sulfamethoxazole (HY-B0322). Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic, used for bacterial infections .
|
-
- HY-14800
-
|
RX-1741
|
Bacterial
Antibiotic
|
Infection
|
|
Radezolid (RX-1741) is a oxazolidinone antibiotic. Radezolid is active against Staphylococcus, Chlamydia, and Legionella species, and remains active against Linezolid-resistant strains .
|
-
- HY-N15050
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Cervicarcin is an antitumor antibiotic with a strong inhibitory effect on sarcoma 180 and sarcoma NF, but has a weak effect on sarcoma 37, Ehrman's ascites cancer and Friend leukemia .
|
-
- HY-W040128
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Kanamycins sulfate is a broad-spectrum antibiotic, can be used in certain severe staphylococcal or Gram-negative bacillary infections. Kanamycin sulfate has certain ototoxicity .
|
-
- HY-N14490
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Coumamidine γ1 is a kind of alkaline sugar Cinodine antibiotic, which has broad spectrum antibacterial activity and also has effect on pseudomonas aeruginosa .
|
-
- HY-13588R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefsulodin (sodium) (Standard) is the analytical standard of Cefsulodin (sodium). This product is intended for research and analytical applications. Cefsulodin (SCE-129) sodium is a third generation β lactam antibiotic and member of the cephems subgroup of antibiotics. Cefsulodin sodium inhibits cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) cross-linking and transpeptidation of peptidogly. Cefsulodin sodium is a potent tyrosine phosphatase inhibitor against mPTPB, a virulent phosphatase from Mycobacterium tuberculosis, with an IC50 value of 16 μM .
|
-
- HY-W653977
-
|
7-Chlorotetracycline-13C,d3 hydrochloride
|
Isotope-Labeled Compounds
Antibiotic
Bacterial
Parasite
|
Infection
|
|
Chlortetracycline-13C,d3 hydrochloride (7-Chlorotetracycline-13C,d3 hydrochloride) is the 13C- and deuterium labeled Chlortetracycline hydrochloride (HY-B1327). Chlortetracycline hydrochloride is an orally active, selective antibiotic, that inhibits methanogenic bacteria through inhibition of bacterial protein synthesis. Chlortetracycline hydrochloride is a specific and potent calcium ionophore antibiotic, that inhibits binding of aminoacyl-tRNA to ribosomes .
|
-
- HY-127146
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Platensimycin is an antibiotic produced by S. platensis that inhibits gram-positive bacteria by selectively inhibiting cellular lipid biosynthesis (IC50=0.1 μM). Platensimycin targets the β-ketoacyl-acyl-carrier-protein synthase I/II, FabF/B, an enzyme that participates in the biosynthesis of fatty acids (IC50s=48 nM and 160 nM for S.aureus and E.coli enzymes, respectively). Platensimycin is a promising agent for overcoming antibiotic resistance.
|
-
- HY-B1275A
-
|
Cephalotin
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
Cardiovascular Disease
|
|
Cephalothin (Cephalotin) is a semi-synthetic cephalosporin antibiotic and beta-lactam antibiotic. Cephalothin inhibits class C β-lactamase AmpC, with an Ki of 0.32 µM. Cephalothin binds to penicillin-binding proteins, interfering with the cross-linking of peptidoglycan in the cell wall and thus hindering the normal synthesis of the bacterial cell wall. Cephalothin shows antibacterial activity against a variety of bacteria. Cephalothin can be used in hematological and nephrotoxicity studies .
|
-
- HY-B1802A
-
|
A-61827 tosylate hydrate; T-3262
|
Bacterial
Antibiotic
|
Infection
|
|
Tosufloxacin tosylate hydrate (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
|
-
- HY-100528
-
|
Nanchangmycin A
|
Bacterial
Antibiotic
Flavivirus
|
Infection
|
|
Nanchangmycin, a polyether antibiotic produced by Streptomyces nanchangensis NS3226, inhibits gram-positive bacteria . Nanchangmycin is a broad spectrum antiviral active against Zika virus .
|
-
- HY-115441
-
|
(Rac)-NND 502
|
Antibiotic
Fungal
|
Infection
|
|
(Rac)-Luliconazole ((Rac)-NND 502) is the racemic isomer of Luliconazole (HY-14283). Luliconazole is a topical antifungal imidazole antibiotic with broad-spectrum and potent antifungal activity .
|
-
- HY-B0875
-
|
SCE-1365 hydrochloride
|
Antibiotic
Bacterial
|
Infection
|
|
Cefmenoxime (SCE-1365) hydrochloride is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .
|
-
- HY-N5169
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Argimicin C is an antibiotic that can be isolated from Sphingomonas sp.. Argimicin C exhibits algicidal activity against a variety of toxic cyanobacteria with MIC of low micromolar levels .
|
-
- HY-W799435
-
|
A-61827 hydrate
|
Antibiotic
Bacterial
|
Infection
|
|
Tosufloxacin (A-61827) tosylate is an orally active fluoroquinolone antibiotic. Tosufloxacin tosylate shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
|
-
- HY-B0875A
-
|
SCE-1365
|
Antibiotic
Bacterial
|
Infection
|
|
Cefmenoxime (SCE-1365) is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .
|
-
- HY-B1921
-
|
Midecamycin acetate; Ponsinomycin
|
Bacterial
|
Infection
|
|
Miocamycin (Midecamycin acetate) is a derivative of midecamycin (HY-B1908), a macrolide antibiotic that can be isolated from a culture broth of Streptomyces mycarofaciens. Miocamycin has antibacterial properties .
|
-
- HY-B0810AR
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Pivmecillinam (hydrochloride) (Standard) is the analytical standard of Pivmecillinam (hydrochloride). This product is intended for research and analytical applications. Pivmecillinam hydrochloride (FL-1039 hydrochloride) is an orally active proagent of mecillinam, an extended-spectrum penicillin antibiotic.
|
-
- HY-W327808
-
|
|
Antibiotic
|
Infection
|
|
DL-Lanthionine is a distinctive amino acid and a monosulfide counterpart to cystine, playing a vital role as a component of peptide antibiotics known as lantiobiotics, which encompass well-known examples such as nisin and subtilin.
|
-
- HY-W749146
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Raja 42 is a gamma lactam antibiotic. Raja 42 is effective against a variety of different bacterias, including Gram-positive and Gram-negative bacteria, such as C. difficile strains .
|
-
- HY-B1802B
-
|
A-61827 hydrochloride
|
Antibiotic
Bacterial
|
Infection
|
|
Tosufloxacin (A-61827) hydrochloride is an orally active fluoroquinolone antibiotic. Tosufloxacin hydrochloride shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
|
-
- HY-B1802C
-
|
A-61827 tosylate
|
Antibiotic
Bacterial
|
Infection
|
|
Tosufloxacin (A-61827) tosylate is an orally active fluoroquinolone antibiotic. Tosufloxacin tosylate shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
|
-
- HY-B0408AR
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Clindamycin (hydrochloride) (Standard) is the analytical standard of Clindamycin (hydrochloride). This product is intended for research and analytical applications. Clindamycin (hydrochloride) is a semisynthetic lincosamide antibiotic, which inhibits protein synthesis by acting on the 50S ribosomal.
|
-
- HY-114658R
-
|
|
Biochemical Assay Reagents
Antibiotic
|
Cancer
|
|
Daunomycinone (Standard) is the analytical standard of Daunomycinone. This product is intended for research and analytical applications. Daunomycinone (NSC-109351) is a metabolite of daunomycin. Daunomycin is an antibiotic with antitumor activity .
|
-
- HY-B0308R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sparfloxacin (Standard) is the analytical standard of Sparfloxacin. This product is intended for research and analytical applications. Sparfloxacin (CI-978) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity .
|
-
- HY-N14760
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Leucomycin A9 is a macrolide antibiotic. Leucomycin A9 has strong anti-Gram-positive bacterial effect, and also has an effect on spirochetes, Rickettsium and Chlamydia .
|
-
- HY-B0698
-
|
Sch 39720
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Ceftibuten (Sch39720), an antibiotic, is an orally active cephalosporin, possesses potent activity in vitro against a wide range of gram-negative and certain gram-positive pathogens .
|
-
- HY-N14018
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Glidobactin A is an acyl peptide antibiotic. Glidobactin A has activity against Candida, Aspergillus fumigatus and Trichophyton, but it is not effective against Candida albicans M-9 infection in mice .
|
-
- HY-P4747
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
LL-37 GKE is an active domain of LL-37. LL-37 GKE has antibacterial activity and has potential applications in antibiotics .
|
-
- HY-N14845
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Napsamycin A is an antibiotic. Napsamycin A has antibacterial activity against Pseudomonas aeruginosa and other pseudomonas, but has weak antibacterial activity against other Gram-positive and negative bacteria .
|
-
- HY-N5168
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Argimicin B is an antibiotic that can be isolated from Sphingomonas sp.. Argimicin B exhibits algicidal activity against a variety of toxic cyanobacteria with MIC of low micromolar levels .
|
-
- HY-B2060
-
|
Thiamutilin
|
Bacterial
Antibiotic
|
Infection
|
|
Tiamulin (Thiamutilin) is a diterpenic antibiotic that is widely used in pigs and poultry for the control of infectious diseases. Tiamulin is effectively used in the study of airsacculitis, which is primarily caused by Mycoplasma spp .
|
-
- HY-N1944A
-
|
|
Bacterial
|
Infection
|
|
cis-Nerolidol is a sesquiterpene alcohol that can be found in various plants. cis-Nerolidol exhibits antioxidant and antibacterial activities. cis-Nerolidol can also potentiate the action of antibiotics .
|
-
- HY-N14830
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
3-Hydroxyrifamycin S is an Ansa antibiotic. 3-Hydroxyrifamycin S has anti-Gram-positive bacteria and weaker anti-Gram-negative bacteria activity .
|
-
- HY-B2060A
-
|
Thiamutilin fumarate
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Tiamulin (Thiamutilin) fumarate is a diterpenic antibiotic that is widely used in pigs and poultry for the control of infectious diseases. Tiamulin fumarate is effectively used in the study of airsacculitis, which is primarily caused by Mycoplasma spp .
|
-
- HY-N6738
-
|
|
Bacterial
Fungal
Antibiotic
|
Infection
|
|
Bafilomycin B1 is a macrolide antibiotic isolated from Streptomyces sp, inhibits Gram-positive bacteria and fungi, and acts as an inhibitor of K +-dependent ATPase of E. coli .
|
-
- HY-125163
-
|
8-O-Methyltetrangomycin; 6-Deoxy-8-O-methylrabelomycin
|
Bacterial
Antibiotic
|
Infection
|
|
MM 47755 (8-O-Methyltetrangomycin; 6-Deoxy-8-O-methylrabelomycin) is an antibiotic with antibacterial activity. MM 47755 can be isolated from Streptomyces .
|
-
- HY-N13880
-
|
|
Antibiotic
Fungal
|
Infection
|
|
Adustin, an antifungal antibiotic, is a polypeptide with translation-inhibiting activity. Adustin inhibits translation in a cell-free rabbit reticulocyte lysate system with an IC50 of 0.34 μM .
|
-
- HY-W441968
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
L-threo-β-Hydroxyaspartic acid is an amino acid antibiotic. L-threo-β-Hydroxyaspartic acid has the activity of inhibiting Bacillus subtilis, Xanthomonas oryzae, Mycobacterium phlei and Botrytis cinerea .
|
-
- HY-B1802
-
|
A-61827
|
Antibiotic
Bacterial
|
Infection
|
|
Tosufloxacin (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
|
-
- HY-N14693
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Pluracidomycin B is a carbapenem antibiotic. Pluracidomycin B has anti-Gram-positive bacteria and Gram-negative bacteria activity, and has the effect of inhibiting β-lactamase .
|
-
- HY-B0300S
-
-
- HY-P3270
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Capreomycin is a macrocyclic peptide antibiotic. Capreomycin can be used for anti-multidrug-resistant-tuberculosis research. Capreomycin can inhibit phenylalanine synthesis in in mycobacterial ribosomes translation
|
-
- HY-N14180
-
|
|
Antibiotic
|
Infection
Cancer
|
|
6-Deoxyilludin M is an antitumor antibiotic possessing antileukemic activity. 6-Deoxyilludin M can be isolated from the culture broth of the Basidiomycota Pleurotus japonicas .
|
-
- HY-B0698B
-
|
Sch 39720 monohydrate
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Ceftibuten (Sch39720) monohydrate, an antibiotic, is an orally active cephalosporin, possesses potent activity in vitro against a wide range of gram-negative and certain gram-positive pathogens .
|
-
- HY-B1824R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Cefpirome sulfate (Standard) is the analytical standard of Cefpirome sulfate. This product is intended for research and analytical applications. Cefpirome sulfate (HR-810 sulfate) is a fourth generation cephalosporin antibiotic.
|
-
- HY-100436R
-
|
ACT-179811 (Standard)
|
Bacterial
Antibiotic
|
Infection
|
|
Cadazolid (Standard) is the analytical standard of Cadazolid. This product is intended for research and analytical applications. Cadazolid (ACT-179811) is a new oxazolidinone antibiotic with potent activity against Clostridium difficile.
|
-
- HY-116010R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Oleandomycin (Standard) is the analytical standard of Oleandomycin. This product is intended for research and analytical applications. Oleandomycin is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity.
|
-
- HY-119673
-
|
|
Antibiotic
|
Others
|
|
Lincophenicol is a hybrid antibiotic that has the activity of inhibiting the puromycin reaction catalyzed by Escherichia coli ribosomal peptidyl transferase and also inhibits the binding of specific compounds to the Escherichia coli ribosome.
|
-
- HY-106959
-
|
(8S)-8-Fluoroerythromycin A; P-0501A
|
Antibiotic
Bacterial
|
Infection
|
|
Flurithromycin ((8S)-8-Fluoroerythromycin A) is an orally active broad spectrum antibiotic. Flurithromycin can be used in the research of bacterial infections .
|
-
- HY-131146R
-
|
|
Antibiotic
|
Infection
|
|
AMOZ (Standard) is the analytical standard of AMOZ. This product is intended for research and analytical applications. AMOZ, a tissue bound metabolite of Furaltadone, Furaltadone is a synthetic nitrofuran antibiotic widely used
|
-
- HY-B1282R
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
Sulfaquinoxaline (Standard) is the analytical standard of Sulfaquinoxaline. This product is intended for research and analytical applications. Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections .
|
-
- HY-B1282AR
-
|
|
Bacterial
Parasite
Antibiotic
|
Infection
|
|
3β-Ursodeoxycholic acid (Standard) is the analytical standard of 3β-Ursodeoxycholic acid. This product is intended for research and analytical applications. 3β-Ursodeoxycholic acid (Isoursodeoxycholic acid) is a bile acid. 3β-Ursodeoxycholic acid shows good tolerance and well intestinal absorption by oral adminstation. 3β-Ursodeoxycholic acid can be isomerized by intestinal and hepatic enzymes to yield UDCA .
|
-
- HY-B1282A
-
