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Results for "

anticholinergic

" in MCE Product Catalog:

73

Inhibitors & Agonists

4

Natural
Products

15

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas
  • HY-43711
    Nor-benzetimide

    mAChR Neurological Disease
    Nor-benzetimide is a major metabolite of Benzetimide. Benzetimide is a mAChR antagonist with anticholinergic activity.
  • HY-N7061
    Tropine

    Others Neurological Disease
    Tropine is a secondary metabolite of Solanaceae plants, is an anticholinergic agent. Tropine is a common intermediate in the synthesis of a variety of bioactive alkaloids, including hyoscyamine and scopolamine.
  • HY-B2112
    Valethamate bromide

    Others Others
    Valethamate bromide is an ester and is a potent rapidly acting anticholinergic spasmolytic and musculotropic agent which accelerates labor by improving cervical dilation.
  • HY-135407S
    N-Desethyl Oxybutynin-d5 hydrochloride

    Drug Metabolite Neurological Disease
    N-Desethyl Oxybutynin D5 hydrochloride is deuterium labeled N-Desethyl Oxybutynin hydrochloride. N-Desethyl Oxybutynin is the the active metabolite Oxybutynin. Oxybutynin is an anticholinergic agent that inhibits voltage-dependent K + channels.
  • HY-117501
    Dexchlorpheniramine

    Histamine Receptor Inflammation/Immunology
    Dexchlorpheniramine is an potent and blood-brain barrier (BBB) penetrant histamine 1 (H1) receptor antagonist with anticholinergic properties. Dexchlorpheniramine can be used for researching allergies.
  • HY-B0761
    (R,R)-Glycopyrrolate

    (R,R)-Glycopyrronium bromide; (R,R)-Glycopyrrolate bromide

    mAChR Neurological Disease
    (R,R)-Glycopyrrolate ((R,R)-Glycopyrronium (bromide); (R,R)-Glycopyrrolate (bromide)) is an anticholinergic agent. (R,R)-Glycopyrrolate ((R,R)-Glycopyrronium (bromide); (R,R)-Glycopyrrolate (bromide)) has the ability to reduce the frequency of drooling in vivo with developmental disabilities.
  • HY-107922
    Ethopropazine hydrochloride

    Isothazine hydrochloride; Lysivane hydrochloride; Parsidol hydrochloride

    Cholinesterase (ChE) Neurological Disease
    Ethopropazine (Isothazine) hydrochloride is a potent, selective BChE inhibitor and a poor AChE inhibitor. Ethopropazine hydrochloride is a phenothiazine compound with anticholinergic properties. Ethopropazine hydrochloride can be used for the research of Parkinson’s disease.
  • HY-B1667
    Isopropamide iodide

    Others Metabolic Disease
    Isopropamide iodide is a long-acting quaternary anticholinergic agent. Isopropamide iodide is used in peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility.
  • HY-W276446
    1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol

    Others Inflammation/Immunology
    1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol is an anticholinergic agent. 1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol has the potential for the research of bronchial asthma.
  • HY-B0548S
    Hydroxyzine D4

    Histamine Receptor Endocrinology Inflammation/Immunology Neurological Disease
    Hydroxyzine D4 is deuterium labeled Hydroxyzine. Hydroxyzine is a heterocyclic histamine H1-receptor antagonist. Hydroxyzine has anticholinergic, anxiolytic and analgesic properties.
  • HY-B0548AS
    Hydroxyzine D4 dihydrochloride

    Histamine Receptor Endocrinology Inflammation/Immunology Neurological Disease
    Hydroxyzine D4 dihydrochloride is deuterium labeled Hydroxyzine. Hydroxyzine is a heterocyclic histamine H1-receptor antagonist. Hydroxyzine has anticholinergic, anxiolytic and analgesic properties.
  • HY-116408A
    Propiverine hydrochloride

    mAChR Calcium Channel Neurological Disease
    Propiverine hydrochloride is a bladder spasmolytic with calcium antagonistic and anticholinergic properties. Propiverine hydrochloride can be used for the research of overactive blaqdder and urinary incontinence.
  • HY-B1483
    Methapyrilene hydrochloride

    Thenylpyramine hydrochloride

    Histamine Receptor Inflammation/Immunology
    Methapyrilene (Thenylpyramine) hydrochloride is an orally active H1-receptor antihistamine and an anticholinergic agent of the pyridine chemical class. Methapyrilene hydrochloride has hepatotoxicity and can be used as a hepatotoxin that cause periportal hepatic necrosis in vivo
  • HY-14263
    Pericyazine

    Propericiazine; RP 8909

    Dopamine Receptor Neurological Disease
    Pericyazine (Propericiazine) is a first-generation antipsychotic agent that is used as an adjunct to the short-term management of severe anxiety states and psychosis. Pericyazine is a selective D2-dopamine receptor antagonist. Pericyazine has adrenolytic, anticholinergic, and extrapyramidal effects.
  • HY-N9337
    Amaroswerin

    NO Synthase Cancer Metabolic Disease Inflammation/Immunology
    Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC50 value of 5.42 μg/mL in RAW264.7 cells.
  • HY-B0480
    Brompheniramine maleate

    (±)-Brompheniramine maleate

    Histamine Receptor Endocrinology Inflammation/Immunology Neurological Disease
    Brompheniramine ((±)-Brompheniramine) maleate is a potent and orally active antihistamine of the propylamine class. Brompheniramine maleate is a selective histamine H1 receptor antagonist with a Kd of 6.06 nM. Brompheniramine maleate has anticholinergic, antidepressant and analgesia properties and can be used for allergic rhinitis research.
  • HY-109013
    Sofpironium bromide

    BBI 4000

    mAChR Neurological Disease
    Sofpironium bromide (BBI 4000) is an anticholinergic agent used in the study of primary axillary hyperhidrosis (PAH). Sofpironium bromide reduces sweating by inhibiting M3 muscarinic receptors in eccrine glands at the application site. Sofpironium bromide also has a high afnity for the M1, M2, M4 and M5 subtypes.
  • HY-B0520A
    Benztropine mesylate

    Benzatropine mesylate; Benzotropine mesylate; Benztropine methanesulfonate

    Dopamine Receptor mAChR Histamine Receptor Cancer Neurological Disease
    Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects.
  • HY-B0520
    Benztropine

    Benzatropine; Benzotropine

    Dopamine Receptor mAChR Histamine Receptor
    Benztropine (Benzatropine; Benzotropine) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine is also a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects.
  • HY-145391
    Triperiden

    Others Infection
    Triperiden is an inhibitor of influenza virus multiplication. Triperiden targets the haemagglutinin of fowl plague virus (FPV) for antiviral activity and acts by inhibiting the conformational change in the haemagglutinin at acid pH. Triperiden is also anticholinergic anti-parkinsonism drug.
  • HY-105793
    Mazaticol

    mAChR Neurological Disease
    Mazaticol is an anticholinergic agent. Mazaticol blocks the muscarinic acetylcholine receptors and cholinergic nerve activity. Mazaticol is a potent 3H-QNB and 3H-PZ binding inhibitor, can bind to the M2 receptors with high affinity. Mazaticol exhibits inhibitory effects on dopamine uptake in the striatal nerve terminal. Mazaticol can be used for parkinsonian syndrome research.
  • HY-B0267C
    (R)-Oxybutynin

    Aroxybutynin

    mAChR Neurological Disease
    (R)-Oxybutynin (Aroxybutynin), a (R)-isomer of Oxybutynin, is an orally active muscarinic receptor antagonist. (R)-Oxybutynin has antimuscarinic, antispasmodic and anticholinergic activity, competitively antagonizes Carbachol-induced contractions. (R)-Oxybutynin can be used for researching incontinence due to neurogenic bladder dysfunction.
  • HY-137976
    Penehyclidine hydrochloride

    Penequinine hydrochloride

    mAChR NF-κB Inflammation/Immunology
    Penehyclidine (Penequinine) hydrochloride, a anticholinergic drug, is a selective antagonist of M1 and M3 receptors. Penehyclidine hydrochloride activates NF-kβ in lung tissue and inhibits the release of inflammatory factors. Penehyclidine hydrochloride can alleviate the pulmonary inflammatory response in rats with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation.
  • HY-142119
    Penehyclidine

    mAChR NF-κB Inflammation/Immunology
    Penehyclidine, a anticholinergic agent, is a selective antagonist of M1 and M3 receptors. Penehyclidine activates NF-kβ in lung tissue and inhibits the release of inflammatory factors. Penehyclidine can alleviate the pulmonary inflammatory response in rats with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation.
  • HY-136587
    Oxomemazine

    Histamine Receptor mGluR Inflammation/Immunology
    Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic properties. Oxomemazine is a selective antagonist for muscarinic M1 receptor, displays about 20-fold difference in the affinity for high (Ki = 84 nM, M1 receptor) and low (Ki = 1.65 μM, M2 receptor) affinity sites. Oxomemazine an antihistamine and anticholinergic agent used for the study of cough treatment.
  • HY-16171
    Diphenmanil methylsulfate

    Diphemanil mesylate

    mAChR Endocrinology
    Diphemanil methylsulfate is a quaternary ammonium anticholinergic.
  • HY-U00132
    Embramine

    Others Inflammation/Immunology
    Embramine is a monoethanolamine used as an antihistamine and anticholinergic.
  • HY-U00203
    Tematropium

    CDDD3602; HGP6

    mAChR Neurological Disease
    Tematropium (CDDD3602) is a soft anticholinergics.
  • HY-U00001
    Phenglutarimid

    Ciba 10870; Phenglutarimide

    mAChR Neurological Disease
    Phenglutarimid is an anticholinergic used as an antiparkinsonian agent.
  • HY-U00082
    Tigloidin

    Tigloyl pseudotropine; Tiglylpseudotropine; Tiglyssin

    Others Inflammation/Immunology
    Tigloidin is an analogue of atropine, with anticholinergic activity.
  • HY-W201842
    Octamylamine

    mAChR Neurological Disease
    Octamylamine is an anticholinergic and antispasmodic agent.
  • HY-B0460
    Tiotropium bromide hydrate

    BA-679 BR (hydrate)

    mAChR Neurological Disease
    Tiotropium Bromide hydrate is an anticholinergic and bronchodilator and a muscarinic receptor antagonist.
  • HY-U00184
    Timepidium bromide

    Sesden; SA504

    mAChR Cardiovascular Disease
    Timepidium bromide (Sesden; SA504) is an anticholinergic agent.
  • HY-U00055
    Temiverine hydrochloride

    mAChR Neurological Disease
    Temiverine hydrochloride is a synthesized drug that is expected to have anticholinergic action.
  • HY-B0547A
    Homatropine Bromide

    Homatropine hydrobromide

    mAChR Neurological Disease
    Homatropine Bromide is muscarinic AChR antagonist that is an anticholinergic medication.
  • HY-B1607
    Chlorphenoxamine

    Histamine Receptor Neurological Disease Endocrinology
    Chlorphenoxamine is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent.
  • HY-B1062
    Dexchlorpheniramine maleate

    S-(+)-Chlorpheniramine maleate salt

    Histamine Receptor Inflammation/Immunology Endocrinology
    Dexchlorpheniramine maleate is an antihistamine, with anticholinergic properties, used to treat allergic conditions.
  • HY-B1487
    Procyclidine hydrochloride

    (±)-Procyclidine hydrochlorid

    iGluR Neurological Disease
    Procyclidine hydrochloride is a potent anti-cholinergic agent, and is also known to have NMDA antagonist properties.
  • HY-B1067
    Antazoline hydrochloride

    Phenazoline hydrochloride

    Histamine Receptor Neurological Disease Endocrinology
    Antazoline hydrochloride is a 1st generation antihistamine with also anticholinergic properties used to relieve nasal congestion and in eye drops.
  • HY-U00105
    Oxitropium Bromide

    mAChR Inflammation/Immunology
    Oxitropium bromide is an mAChR antagonist used as an anticholinergic bronchodilator drug for the treatment of asthma and chronic obstructive pulmonary disease.
  • HY-B0267A
    Oxybutynin chloride

    mAChR Potassium Channel Neurological Disease
    Oxybutynin chloride is an anticholinergic agent, which inhibits vascular Kv channels in a concentration-dependent manner, with an IC50 of 11.51 μM.
  • HY-B0267
    Oxybutynin

    mAChR Potassium Channel Neurological Disease
    Oxybutynin is an anticholinergic agent, which inhibits vascular Kv channels in a concentration-dependent manner, with an IC50 of 11.51 μM.
  • HY-B1487S
    Procyclidine-d11 hydrochloride

    iGluR Neurological Disease
    Procyclidine-d11 hydrochloride is the deuterium labeled Procyclidine hydrochloride. Procyclidine hydrochloride is a potent anti-cholinergic agent, and is also known to have NMDA antagonist properties.
  • HY-105545
    Dexetimide

    (+)-Benzetimide; (S)-(+)-Dexetimide; Dexbenzetimide

    mAChR Neurological Disease
    Dexetimide ((+)-Benzetimide) is a high-affinity muscarinic receptor antagonist and a potent and persistent anticholinergic agent used to treat neuroleptic-induced parkinsonism.
  • HY-B1062S
    Dexchlorpheniramine-d6 maleate

    S-(+)-Chlorpheniramine-d6 maleate

    Histamine Receptor Inflammation/Immunology Endocrinology
    Dexchlorpheniramine-d6 (S-(+)-Chlorpheniramine-d6) maleateis the deuterium labeled Dexchlorpheniramine maleate. Dexchlorpheniramine maleate is an antihistamine, with anticholinergic properties, used to treat allergic conditions.
  • HY-B1277
    Trihexyphenidyl hydrochloride

    mAChR Neurological Disease
    Trihexyphenidyl hydrochloride is a potent and selective M1 muscarinic receptor antagonist. Trihexyphenidyl hydrochloride shows anticholinergic activity, and can be used for Parkinson syndrome or dystonia research.
  • HY-120081A
    Metixene hydrochloride hydrate

    mAChR Neurological Disease
    Metixene hydrochloride hydrate is an anticholinergic antiparkinsonian agent, potently inhibits binding of quinuclidinyl benzilate (QNB) to the muscarinic receptor in rat brain cortical tissue, with an IC50 of 55 nM and a Kd of 15 nM.
  • HY-120081B
    Metixene hydrochloride

    mAChR Neurological Disease
    Metixene hydrochloride is an anticholinergic antiparkinsonian agent, potently inhibits binding of quinuclidinyl benzilate (QNB) to the muscarinic receptor in rat brain cortical tissue, with an IC50 of 55 nM and a Kd of 15 nM.
  • HY-105710
    Tropatepine

    Others Neurological Disease
    Tropatepine is an orally active, anticholinergic muscarinic antagonist and can be used as an antiparkinsonian agent. Tropatepine is used to combat against extrapyramidal syndrome induced by neuroleptic drugs.
  • HY-B0267AS
    Oxybutynin-d11 chloride

    mAChR Potassium Channel Neurological Disease
    Oxybutynin-d11 chloride is the deuterium labeled Oxybutynin chloride. Oxybutynin chloride is an anticholinergic agent, which inhibits vascular Kv channels in a concentration-dependent manner, with an IC50 of 11.51 μM.
  • HY-B0303A
    Diphenhydramine hydrochloride

    Histamine Receptor Endogenous Metabolite Inflammation/Immunology Endocrinology
    Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB).
  • HY-B0303
    Diphenhydramine

    Histamine Receptor Endogenous Metabolite Inflammation/Immunology
    Diphenhydramine is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB).
  • HY-116408AS
    Propiverine-d7 hydrochloride

    mAChR Calcium Channel Neurological Disease
    Propiverine-d7 hydrochloride is the deuterium labeled Propiverine hydrochloride. Propiverine hydrochloride is a bladder spasmolytic with calcium antagonistic and anticholinergic properties. Propiverine hydrochloride can be used for the research of overactive blaqdder and urinary incontinence.
  • HY-B1470
    Azaperone

    R-1929

    Dopamine Receptor Neurological Disease
    Azaperone (R-1929) acts as a dopamine antagonist but also has some antihistaminic and anticholinergic properties. Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic drug with antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.
  • HY-B0303AS1
    Diphenhydramine-d5 hydrochloride

    Histamine Receptor Endogenous Metabolite Inflammation/Immunology Endocrinology
    Diphenhydramine-d5 hydrochloride is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB).
  • HY-B0303AS
    Diphenhydramine-d6 hydrochloride

    Histamine Receptor Endogenous Metabolite Inflammation/Immunology Endocrinology
    Diphenhydramine-d6 hydrochloride is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB).
  • HY-108974
    Drotaverine hydrochloride

    Phosphodiesterase (PDE) Calcium Channel
    Drotaverine (hydrochloride) is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor and an L-type voltage-dependent calcium channel (L-VDCC) blocker, blocks the degradation of 3',5'-cyclic adenosine monophosphate. Drotaverine (hydrochloride) exhibits in vivo antispasmodic efficacy without anticholinergic effects.
  • HY-N6608
    Physostigmine

    Eserine

    Cholinesterase (ChE) Neurological Disease
    Physostigmine (Eserine) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine is also an antidote for anticholinergic poisoning.
  • HY-B0461
    Trospium chloride

    mAChR Neurological Disease
    Trospium chloride is an orally active, specific and competitive antagonist of muscarinic cholinergic receptors (mAChRs), with antimuscarinic activity. Trospium chloride binds to muscarinic receptors M1, M2 and M3 with high affinity, but not nicotinic, cholinergic receptors.
  • HY-13204B
    Biperiden lactate

    KL 373 lactate

    mAChR Neurological Disease
    Biperiden (KL 373) lactate is an orally active non-selective muscarinic receptor antagonist that competitively binds to M1 muscarinic receptors. Biperiden (KL 373) lactate inhibits acetylcholine and enhances dopamine signaling in the central nervous system. Biperiden (KL 373) lactate has the potential for the research of Parkinson's disease and other related psychiatric disorders.
  • HY-13204
    Biperiden hydrochloride

    KL 373 hydrochloride

    mAChR Neurological Disease
    Biperiden (KL 373) hydrochloride is a non-selective muscarinic receptor antagonist that competitively binds to M1 muscarinic receptors, thereby inhibiting acetylcholine and enhancing dopamine signaling in the central nervous system. Biperiden hydrochloride has the potential for the research of Parkinson's disease and other related psychiatric disorders.
  • HY-13204A
    Biperiden

    KL 373

    mAChR Neurological Disease
    Biperiden (KL 373) is a non-selective muscarinic receptor antagonist that competitively binds to M1 muscarinic receptors, thereby inhibiting acetylcholine and enhancing dopamine signaling in the central nervous system. Biperiden has the potential for the research of Parkinson's disease and other related psychiatric disorders.
  • HY-B1266
    Physostigmine salicylate

    Eserine salicylate

    Cholinesterase (ChE) Neurological Disease
    Physostigmine salicylate (Eserine salicylate) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine salicylate crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine salicylate can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine salicylate is also an antidote for anticholinergic poisoning.
  • HY-B1470S
    Azaperone-d4

    R-1929-d4

    Dopamine Receptor Neurological Disease
    Azaperone-d4 (R-1929-d4) is the deuterium labeled Azaperone. Azaperone (R-1929) acts as a dopamine antagonist but also has some antihistaminic and anticholinergic properties. Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic drug with antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.
  • HY-N2320
    Physostigmine hemisulfate

    Eserine hemisulfate

    Cholinesterase (ChE) Neurological Disease
    Physostigmine hemisulfate (Eserine hemisulfate) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine hemisulfate can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine hemisulfate can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine hemisulfate is also an antidote for anticholinergic poisoning.
  • HY-108974S
    Drotaverine-d10 hydrochloride

    Phosphodiesterase (PDE) Calcium Channel
    Drotaverine-d10 hydrochloride is the deuterium labeled Drotaverine hydrochloride. Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor and an L-type voltage-dependent calcium channel (L-VDCC) blocker, blocks the degradation of 3',5'-cyclic adenosine monophosphate. Drotaverine hydrochloride exhibits in vivo antispasmodic efficacy without anticholinergic effects.
  • HY-N6608S
    Physostigmine-d3

    Eserine-d3

    Cholinesterase (ChE) Neurological Disease
    Physostigmine-d3 (Eserine-d3) is the deuterium labeled Physostigmine. Physostigmine (Eserine) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine is also an antidote for anticholinergic poisoning.
  • HY-14263S
    Pericyazine-d4

    Dopamine Receptor Neurological Disease
    Pericyazine-d4 (Propericiazine-d4) is the deuterium labeled Pericyazine. Pericyazine (Propericiazine) is a first-generation antipsychotic agent that is used as an adjunct to the short-term management of severe anxiety states and psychosis. Pericyazine is a selective D2-dopamine receptor antagonist. Pericyazine has adrenolytic, anticholinergic, and extrapyramidal effects.
  • HY-106577
    Cibenzoline

    Cifenline; Ro 22-7796

    Potassium Channel Cardiovascular Disease
    Cibenzoline is a potent inhibitor of KATP channel with directly affecting the pore-forming Kir6.2 subunit rather than the SUR1 subunit. Cibenzoline is a class Ia antiarrhythmic drug. Cibenzoline has little anticholinergic activity. Cibenzoline markedly attenuate LVPG which has a close relationship with myocardial contractility decreasing. Cibenzoline has the potential for the research of hypertrophic obstructive cardiomyopathy.
  • HY-U00050
    (E)-10-Hydroxynortriptyline

    E-10-OH-NT

    Drug Metabolite Neurological Disease
    (E)-10-Hydroxynortriptyline (E-10-OH-NT) is a metabolite of Nortriptyline (HY-B1417). Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline (HY-B0527A). E-10-OH-NT is about 50% as potent as nortriptyline as an inhibitor of the neuronal uptake of norepinephrine in vitro and exhibits less anticholinergic effects in man.
  • HY-B1339
    Dicyclomine hydrochloride

    Dicycloverine hydrochloride

    mAChR Neurological Disease
    Dicyclomine hydrochloride is a potent and orally active muscarinic cholinergic receptors antagonist. Dicyclomine hydrochloride shows high affinity for muscarinic M1 receptor subtype (Ki=5.1 nM) and M2 receptor subtype (Ki=54.6 nM) in brush-border membrane and basal plasma membranes, respectively. Dicyclomine is an antispasmodic agent and relieves smooth muscle spasm of the gastrointestinal tract in vivo.
  • HY-B1339A
    Dicyclomine

    Dicycloverine

    mAChR
    Dicyclomine (Dicycloverine) is a potent and orally active muscarinic cholinergic receptors antagonist. Dicyclomine (Dicycloverine) shows high affinity for muscarinic M1 receptor subtype (Ki=5.1 nM) and M2 receptor subtype (Ki=54.6 nM) in brush-border membrane and basal plasma membranes, respectively. Dicyclomine is an antispasmodic agent and relieves smooth muscle spasm of the gastrointestinal tract in vivo.
  • HY-B0520AS
    Benztropine-13C,d3 mesylate

    Dopamine Receptor mAChR Histamine Receptor Cancer Neurological Disease
    Benztropine-13C,d3 (mesylate) is the 13C- and deuterium labeled Benztropine (mesylate). Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects.