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BMS-587101 is a potent and orally active antagonist of leukocyte function associated antigen-1(LFA-1). BMS-587101 has anti-inflammatory effects and can be used for rheumatoid arthritis research [1] .
BIRT 377 is a potent amd orally bioavailable inhibitor of the interaction between intercellular adhesion molecule-1 (ICAM-1) and lymphocyte function-associated antigen-1(LFA-1), with a Ki of 25.8 nM. BIRT 377 also inhibits the production of IL-2 in vivo. BIRT 377 can be used for researching inflammatory and immune disorders [1].
BI-1950 is a highly potent lymphocyte function associated antigen-1(LFA-1) inhibitor. LFA-1 is an essential component in normal immune system function and a target for agent discovery [1].
RWJ 50271 is an selective and orally active inhibitor of lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction with an IC50 of 5.0 μM (HL60 cells). RWJ 50271 inhibits LFA-1/ICAM-1-mediated cell adhesion [1].
Diacylglyceride, a natural scaffolding lipid, is a hapten that binds to CD1b. Diacylglyceride can be combined with carrier proteins and used in the design of antigens .
FXh is a functionalized hapten activated by incubation with N, N′-disuccinimidyl carbonate, and Et3N in acetonitrile at 0 °C. FXh can improve the affinity of antigens .
Bocconoline is a potent early endosome antigen 1(EEA1) inhibitor. Bocconoline can be isolated from Macleaya cordata. Bocconoline can be used for the research of Parkinson’s disease (PD) [1].
AMOZ-CHPh-3-acid is hapten against furaltadone metabolite AMOZ. AMOZ-CHPh-3-acid can couple to BSA for immunogens and couple to OVA for coating antigen .
Nucleoprotein (396-404) is the 396 to 404 fragment of lymphocytic choriomeningitis virus (LCMV). Nucleoprotein (396-404) is the H-2D(b)-restricted immunodominant epitope and can be used as a molecular model of viral antigen .
AB-729 sodium is a siRNA specifically designed to inhibit viral replication and reduces HBVantigens . AB-729 conjugates to a trimer of N-acetylgalactosamine (GalNAc) ligand that promotes uptake into hepatocytes via the asialoglycoprotein receptor (ASGR).
NCGC00262650 is a potent apical membrane antigen 1-rhoptry neck protein 2 (AMA1-RON2) interaction inhibitor. NCGC00262650 can block entry of merozoites into red blood cells [1].
Nucleoprotein (396-404) TFA is the 396 to 404 fragment of lymphocytic choriomeningitis virus (LCMV). Nucleoprotein (396-404) TFA is the H-2D(b)-restricted immunodominant epitope and can be used as a molecular model of viral antigen .
AMOZ-CHPh-4-O-acid is a hapten, containing 2 carbon and 1 oxygen spacer. AMOZ-CHPh-4-O-acid can be used for antibody production. AMOZ-CHPh-4-O-acid is coupled to BSA for immunogens and coupled to OVA for coating antigens .
EBNA1-IN-SC7 (compound SC7) is a selective Epstein-Barr nuclear antigen 1(EBNA1) inhibitor that interferes with EBNA1-DNA binding activity with an IC50 value of 23 μM. EBNA1-IN-SC7 is used in EBV (Epstein-Barr virus)-related cancer research [1].
ent-16-Kaurene-3b,15b,18-triol is a ent-kaurene diterpene. ent-16-Kaurene-3b,15b,18-triol has significant antiallergic activity on β-hexosaminidase release induced by Polyginseng antigen .
Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease [1].
Lifitegrast (SAR 1118) sodium is a potent integrin antagonist. Lifitegrast sodium blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast sodium inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast sodium can be used for researching dry eye disease [1].
alpha-1,4-Galactosyltransferase (LgtC) (A4GALT) is a glycosphingolipid-specific glycosyltransferase. alpha-1,4-Galactosyltransferase (LgtC) transfers a galactose to the alpha-1,4 position of lactosylceramide to form globotriaosylceramide. alpha-1,4-Galactosyltransferase (LgtC) can be used for the synthesis of P1 blood group antigens .
Celestine Blue is a electroactive indicator in DNA biosensors. Celestine Blue is strongly adsorbed on the spinel phases and CNT (carbon nanotubes), facilitates dispersion, acts as a capping agent and allows for the fabrication of spinel decorated CNT. Celestine Blue is an efficient charge transfer mediator, which allows for significant improvement of capacitive behavior. TiO2 nanoparticles doped with Celestine Blue can be used as a label in a sandwich immunoassay for the hepatitis C virus (HCV) core antigen .
Celestine Blue is a electroactive indicator in DNA biosensors. Celestine Blue is strongly adsorbed on the spinel phases and CNT (carbon nanotubes), facilitates dispersion, acts as a capping agent and allows for the fabrication of spinel decorated CNT. Celestine Blue is an efficient charge transfer mediator, which allows for significant improvement of capacitive behavior. TiO2 nanoparticles doped with Celestine Blue can be used as a label in a sandwich immunoassay for the hepatitis C virus (HCV) core antigen .
Fucosyltransferase 5 (EC:2.4.1.65, Fucosyltransferase 5, Fucosyltransferase V) is responsible for the terminal step in the synthesis of Lex, sialy-Lex, and Lea antigens .
Fucosyltransferase 7 (FUT7) is a golgi stack membrane protein. Fucosyltransferase 7catalyzes the final fucosylation step in the synthesis of Lewis antigens and generates a unique glycosylated product sialyl Lewis X (sLeX). Fucosyltransferase 7 catalyzes alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens .
alpha-1,2-Fucosyltransferase (α1,2FucT), i.e., alpha 1, 2-fucosyltransferase, is often used in biochemical studies. alpha-1,2-Fucosyltransferase is a rate-limiting enzyme, can catalyze the synthesis of Lewis y (a cell membrane-associated carbohydrate antigen) .
Nucleoprotein (396-404) is the 396 to 404 fragment of lymphocytic choriomeningitis virus (LCMV). Nucleoprotein (396-404) is the H-2D(b)-restricted immunodominant epitope and can be used as a molecular model of viral antigen .
Nucleoprotein (396-404) TFA is the 396 to 404 fragment of lymphocytic choriomeningitis virus (LCMV). Nucleoprotein (396-404) TFA is the H-2D(b)-restricted immunodominant epitope and can be used as a molecular model of viral antigen .
Lys-Pro-Pro-Thr-Pro-Pro-Pro-Glu-Pro-Glu-Thr is a undecapeptide, corresponding to the carboxy terminus of simian virus 40 large T antigen. Lys-Pro-Pro-Thr-Pro-Pro-Pro-Glu-Pro-Glu-Thr can be targeted by antibodies secreted from three mouse hybridomas, designated KT1, KT3, and KT4, produced antibodies that immunoprecipitated large T antigen .
Bocconoline is a potent early endosome antigen 1(EEA1) inhibitor. Bocconoline can be isolated from Macleaya cordata. Bocconoline can be used for the research of Parkinson’s disease (PD) [1].
ent-16-Kaurene-3b,15b,18-triol is a ent-kaurene diterpene. ent-16-Kaurene-3b,15b,18-triol has significant antiallergic activity on β-hexosaminidase release induced by Polyginseng antigen .
MPZL2 Protein centrally facilitates homophilic cell-cell adhesion, mediating crucial interactions between cells. Its unique ability to promote connections between identical molecules makes MPZL2 instrumental in fostering cellular cohesion and maintaining structural integrity. The protein's specificity in homophilic adhesion underscores its significance in various biological processes, emphasizing its essential role in coordinating cell interactions, facilitating communication, and promoting cooperation between neighboring cells. MPZL2 Protein, Human (HEK293, hFc) is the recombinant human-derived MPZL2 protein, expressed by HEK293, with C-hFc labeled tag. The total length of MPZL2 Protein, Human (HEK293, hFc) is 128 a.a., with molecular weight of 50-60 kDa.
The Serpin B3 protein exhibits versatility in cellular regulation and may act as a papain-like cysteine protease inhibitor to modulate immune responses against tumor cells. Its dual role extends to inhibiting UV-induced apoptosis by inhibiting c-Jun NH(2)-terminal kinase (JNK1) activity, suggesting that Serpin B3 is involved in the stress response. Serpin B3 Protein, Human (HEK293, His) is the recombinant human-derived Serpin B3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin B3 Protein, Human (HEK293, His) is 390 a.a., with molecular weight of 41-50 kDa.
MPZL2 protein mediates homophilic cell-cell adhesion. MPZL2 Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived MPZL2 protein, expressed by HEK293, with C-hFc labeled tag. The total length of MPZL2 Protein, Mouse (HEK293, hFc) is 128 a.a., with molecular weight of 50-60 kDa.
DNAM-1 protein is a key player in cell-cell adhesion and lymphocyte signaling, mediating cytotoxicity and lymphokine secretion of CTL and NK cells. As a receptor for NECTIN2, DNAM-1 stimulates T cell proliferation and cytokine production (IL2, IL5, IL10, IL13, and IFNG) upon ligand binding. DNAM-1 Protein, Human (HEK293, hFc, Myc) is the recombinant human-derived DNAM-1 protein, expressed by HEK293 , with C-Myc, C-hFc labeled tag. The total length of DNAM-1 Protein, Human (HEK293, hFc, Myc) is 229 a.a., with molecular weight of 56.1 kDa.
Galectin-8/LGALS8 Protein, a vital enzyme in glycosylation, serves as a beta-1,3-N-acetylglucosaminyltransferase, synthesizing poly-N-acetyllactosamine. Crucial for modifying glycoproteins and glycolipids, Galectin-8/LGALS8 catalyzes N-acetylglucosamine transfer onto acceptor molecules, exhibiting specific activity for type 2 oligosaccharides. Its role in poly-N-acetyllactosamine synthesis emphasizes its significance in modulating cellular interactions, impacting various processes like cell adhesion, signaling, and recognition events through glycan structure alterations. Galectin-8/LGALS8 Protein, Human is the recombinant human-derived Galectin-8/LGALS8 protein, expressed by E. coli, with tag free. The total length of Galectin-8/LGALS8 Protein, Human is 317 a.a., with molecular weight of ~36 kDa.
The CT83 protein shows specific expression in the testis, highlighting its selective presence in this reproductive organ. In addition, multiple cancer cell lines express CT83, suggesting a potential association with malignancy. CT83 Protein, Human (His, B2M) is the recombinant human-derived CT83 protein, expressed by E. coli , with N-His, B2M labeled tag. The total length of CT83 Protein, Human (His, B2M) is 113 a.a., with molecular weight of ~26.8 kDa.
CD157 Protein, Human (HEK293, Fc) is a recombinant human CD157 expressed in HEK 293 cells with a C-Fc tag at the C-terminus. CD157 Protein is a cell surface receptor and an immunoregulatory molecule.
Galectin-8/LGALS8 Protein, a vital enzyme in glycosylation, serves as a beta-1,3-N-acetylglucosaminyltransferase, synthesizing poly-N-acetyllactosamine. Crucial for modifying glycoproteins and glycolipids, Galectin-8/LGALS8 catalyzes N-acetylglucosamine transfer onto acceptor molecules, exhibiting specific activity for type 2 oligosaccharides. Its role in poly-N-acetyllactosamine synthesis emphasizes its significance in modulating cellular interactions, impacting various processes like cell adhesion, signaling, and recognition events through glycan structure alterations. Animal-Free Galectin-8/LGALS8 Protein, Human (His) is the recombinant human-derived animal-FreeGalectin-8/LGALS8 protein, expressed by E. coli, with N-His labeled tag. The total length of Animal-Free Galectin-8/LGALS8 Protein, Human (His) is 316 a.a., with molecular weight of ~36.6 kDa.
CD157 Protein, Human (HEK293, His) is a recombinant human CD157 expressed in HEK 293 cells with a His tag at the N-terminus. CD157 Protein is a cell surface receptor and an immunoregulatory molecule.
CD157 Protein, Mouse (HEK293, His) is a recombinant mouse CD157 expressed in HEK 293 cells with a His tag at the N-terminus. CD157 Protein is a cell surface receptor and an immunoregulatory molecule.
LY6E is a GPI-anchored cell surface protein that regulates T lymphocyte function by binding to CD3Z/CD247, affecting proliferation, differentiation and activation. It modulates T cell receptor signaling and exhibits antiviral activity against mouse hepatitis virus. Lymphocyte antigen 6E/LY6E Protein, Mouse (P.pastoris, His, SUMO) is the recombinant mouse-derived Lymphocyte antigen 6E/LY6E protein, expressed by P. pastoris , with N-His, N-SUMO labeled tag. The total length of Lymphocyte antigen 6E/LY6E Protein, Mouse (P.pastoris, His, SUMO) is 82 a.a., with molecular weight of ~24.8 kDa.
Lymphocyte antigen 6E/LY6E protein is a GPI-anchored cell surface regulator that regulates T cell receptor signaling through interaction with CD3Z/CD247. It limits the entry of human coronaviruses, serves as the primary receptor for syncytin-A, and may modulate nicotinic acetylcholine receptor activity. Lymphocyte antigen 6E/LY6E Protein, Human (His-SUMO) is the recombinant human-derived Lymphocyte antigen 6E/LY6E protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of Lymphocyte antigen 6E/LY6E Protein, Human (His-SUMO) is 81 a.a., with molecular weight of ~24.5 kDa.
Galectin-8/LGALS8 Protein, a vital enzyme in glycosylation, serves as a beta-1,3-N-acetylglucosaminyltransferase, synthesizing poly-N-acetyllactosamine. Crucial for modifying glycoproteins and glycolipids, Galectin-8/LGALS8 catalyzes N-acetylglucosamine transfer onto acceptor molecules, exhibiting specific activity for type 2 oligosaccharides. Its role in poly-N-acetyllactosamine synthesis emphasizes its significance in modulating cellular interactions, impacting various processes like cell adhesion, signaling, and recognition events through glycan structure alterations. Galectin-8/LGALS8 Protein, Human (GST) is the recombinant human-derived Galectin-8/LGALS8 protein, expressed by E. coli, with N-GST labeled tag. The total length of Galectin-8/LGALS8 Protein, Human (GST) is 317 a.a., with molecular weight of 62.8 kDa.
Advanced glycosylation end product specific receptor; Advanced glycosylation end product-specific receptor; AGER; EC 2.7.11.22; LE 9211 A antigen; LE-9211-A antigen; MGC22357; MOK; RAGE 1; RAGE1; MOK protein kinase; Receptor for advanced glycation endproducts; Renal tumor antigen 1; Renal tumor antigen; Renal cell carcinoma antigen (MOK protein kinase); Renal tumor antigen 1; RAGE_HUMAN.
WB; ELISA; IHC-P; IHC-F; Flow-Cyt; IF
Human, Mouse, Rat,
RAGE Antibody is an unconjugated, approximately 42 kDa, rabbit-derived, anti-RAGE polyclonal antibody. RAGE Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, background without labeling.
CD90/Thy-1 Antibody is an unconjugated, approximately 12 kDa, rabbit-derived, anti-CD90/Thy-1 polyclonal antibody. CD90/Thy-1 Antibody can be used for: WB, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, and predicted: dog, pig, horse, sheep background without labeling.
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