Search Result

Results for "

antimuscarinic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Calcium Channel (1) Histamine Receptor (3) mAChR (21) mGluR (1) Opioid Receptor (1)
By Research Areas:	Endocrinology (1) Inflammation/Immunology (3) Metabolic Disease (4) Neurological Disease (22)

Inhibitors & Agonists

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1132

Clidinium bromide Ro 2-3773	mAChR	Neurological Disease
Clidinium bromide is a quaternary amine *antimuscarinic* agent. Clidinium bromide may help symptoms of cramping and abdominal/stomach pain by decreasing stomach acid, and slowing the intestines in vivo .

HY-B1621A

Cyclopentolate hydrochloride DL-Cyclopentolate hydrochloride	mAChR	Neurological Disease
Cyclopentolate (DL-Cyclopentolate) hydrochloride is an Atropine-like muscarinic receptors antagonist with a pK_B value of 7.8 (on the circular ciliary muscle). Cyclopentolate hydrochloride is an anti-muscarinic agent commonly used in the ophthalmologic practice .

HY-B1806A

Tridihexethyl chloride Pathilon chloride	mAChR	Neurological Disease Inflammation/Immunology
Tridihexethyl (Pathilon) chloride is an orally active anticholinergic agent and mAChR antagonist, shows activities of antimuscarinic and anticholinergic. Tridihexethyl chloride shows pronounced antispasmodic and antisecretory effects on the gastrointestinal tract. Tridihexethyl chloride can be used in studies of peptic ulcer disease and acquired nystagmus .

HY-121168

Aprophen

Aprofene
mAChR Neurological Disease

Aprophen (Aprofene) is an antimuscarinic inhibitor. Aprophen can be used for the research of central nervous system .

Aprophen Aprofene	mAChR	Neurological Disease
Aprophen (Aprofene) is an antimuscarinic inhibitor. Aprophen can be used for the research of central nervous system .

HY-B0267C

(R)-Oxybutynin Aroxybutynin	mAChR	Neurological Disease
(R)-Oxybutynin (Aroxybutynin) is the racemic isomer of Oxybutynin and an orally active muscarinic receptor antagonist. (R)-Oxybutynin has antispasmodic, antimuscarinic, and anticholinergic activities and competitively antagonizes carbachol-induced contractions. (R)-Oxybutynin can be used to study urinary incontinence caused by neurogenic bladder dysfunction .

HY-136587

Oxomemazine	Histamine Receptor mGluR	Inflammation/Immunology
Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic properties. Oxomemazine is a selective antagonist for muscarinic M1 receptor, displays about 20-fold difference in the affinity for high (K_i= 84 nM, M1 receptor) and low (K_i= 1.65 μM, M2 receptor) affinity sites . Oxomemazine an antihistamine and anticholinergic agent used for the study of cough treatment .

HY-B0267B

(R)-Oxybutynin hydrochloride Aroxybutynin hydrochloride	mAChR	Neurological Disease
(R)-Oxybutynin hydrochloride, a (R)-isomer of Oxybutynin hydrochloride, is an orally active muscarinic receptor antagonist. (R)-Oxybutynin hydrochloride has antimuscarinic, antispasmodic and anticholinergic activity, competitively antagonizes Carbachol-induced contractions. (R)-Oxybutynin hydrochloride can be used for researching incontinence due to neurogenic bladder dysfunction . (R)-Oxybutynin (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B1230

Camylofine

mAChR Neurological Disease

Camylofin is an antimuscarinic, is a smooth muscle relaxant
HY-B0380

Trimebutine

Opioid Receptor Metabolic Disease

Trimebutine is a drug with antimuscarinic and weak mu opioid agonist effects.
HY-122086

Prifinium bromide

mAChR Neurological Disease

Prifinium bromide is antimuscarinic agent with antispasmodic, antiemetic effect .
HY-B0962

Piperidolate hydrochloride

mAChR Neurological Disease

Piperidolate hydrochloride is an antimuscarinic, inhibits intestinal cramp induced by acetylcholine (rats and dogs).
HY-B0962A

Piperidolate

mAChR Neurological Disease

Piperidolate is an antimuscarinic, inhibits intestinal cramp induced by acetylcholine (rats and dogs).
HY-U00030

Rispenzepine

mAChR Neurological Disease

Rispenzepine is a novel antimuscarinic compound with a preferential action at M₁, and M₃ receptor subtypes.

Camylofine	mAChR	Neurological Disease
Camylofin is an antimuscarinic, is a smooth muscle relaxant

Trimebutine	Opioid Receptor	Metabolic Disease
Trimebutine is a drug with antimuscarinic and weak mu opioid agonist effects.

Prifinium bromide	mAChR	Neurological Disease
Prifinium bromide is antimuscarinic agent with antispasmodic, antiemetic effect .

Piperidolate hydrochloride	mAChR	Neurological Disease
Piperidolate hydrochloride is an antimuscarinic, inhibits intestinal cramp induced by acetylcholine (rats and dogs).

Piperidolate	mAChR	Neurological Disease
Piperidolate is an antimuscarinic, inhibits intestinal cramp induced by acetylcholine (rats and dogs).

Rispenzepine	mAChR	Neurological Disease
Rispenzepine is a novel antimuscarinic compound with a preferential action at M₁, and M₃ receptor subtypes.

HY-B1132S

Clidinium-D5 bromide Ro 2-3773-d₅	mAChR	Neurological Disease
Clidinium-d₅ (bromide) is the deuterium labeled Clidinium bromide. Clidinium bromide is a quaternary amine antimuscarinic agent[1].

HY-B1188S

Propantheline-d3 bromide	mAChR	Neurological Disease
Propantheline-d₃ (bromide) is the deuterium labeled Propantheline bromide. Propantheline bromide is an antimuscarinic agent, used for the treatment of hyperhidrosis, cramps or spasms of the stomach, intestines or bladder, and enuresis.

HY-B0461

Trospium chloride	mAChR	Neurological Disease
Trospium chloride is an orally active, specific and competitive antagonist of muscarinic cholinergic receptors (mAChRs), with antimuscarinic activity. Trospium chloride binds to muscarinic receptors M1, M2 and M3 with high affinity, but not nicotinic, cholinergic receptors .

HY-116408

Propiverine	mAChR	Neurological Disease
Propiverine is a potent antimuscarinic agent. Propiverine inhibits cellular calcium influx, thereby diminishing muscle spasm. Propiverine has neurotropic and musculotropic effects on the urinary bladder smooth muscle. Propiverine can used for overactive bladder (OAB) research .

HY-B0970

Diphenylpyraline hydrochloride 4-Diphenylmethoxy-1-methylpiperidine hydrochloride	Histamine Receptor	Neurological Disease Endocrinology
Diphenylpyraline hydrochloride is a potent histamine H₁ receptor antagonist. Diphenylpyraline hydrochloride acts as an orally active antihistamine agent with antimuscarinic and antiallergic effects. Diphenylpyraline hydrochloride can be used for the relief of allergic conditions including rhinitis and hay fever, and in pruritic skin disorders in vivo.

HY-107431

Diphenylpyraline	Histamine Receptor	Inflammation/Immunology
Diphenylpyraline is a potent histamine H₁ receptor antagonist. Diphenylpyraline acts as an orally active antihistamine agent with antimuscarinic and antiallergic effects. Diphenylpyraline can be used for the research of allergic diseases, including rhinitis and hay fever, and pruritic skin disorders et.al .

HY-B0461S

Trospium-d8 chloride	mAChR	Neurological Disease
Trospium-d₈ (chloride) is the deuterium labeled Trospium chloride. Trospium chloride is an orally active, specific and competitive antagonist of muscarinic cholinergic receptors (mAChRs), with antimuscarinic activity. Trospium chloride binds to muscarinic receptors M1, M2 and M3 with high affinity, but not nicotinic, cholinergic receptors[1][2].

HY-B1789

Telenzepine	mAChR	Neurological Disease
Telenzepine is an antimuscarinic agent with Kis of 0.94 nM (M1 mAChR) and 17.8 nM (M2 mAChR) binding to muscarinic receptors. Telenzepine effectively blocks synaptic transmission promoted by muscarinic or M1 receptor agonists. Thus, Telenzepine can reduce the amplitude of extracellular slow excitatory postsynaptic potentials (EC50=38 nM) and slow inhibitory postsynaptic potentials (EC50=253 nM) .

HY-116408A

Propiverine hydrochloride	mAChR Calcium Channel	Neurological Disease
Propiverine hydrochloride is a bladder spasmolytic with calcium antagonistic and anticholinergic properties. Propiverine hydrochloride can be used for the research of overactive blaqdder and urinary incontinence .

HY-A0030

Fesoterodine fumarate	mAChR	Neurological Disease Metabolic Disease
Fesoterodine Fumarate is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pK_i values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine Fumarate is used for the overactive bladder (OAB) .

HY-70053

Fesoterodine	mAChR	Neurological Disease Metabolic Disease
Fesoterodine is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pK_i values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine is used for the overactive bladder (OAB) .

HY-70053A

Fesoterodine L-mandelate	mAChR	Neurological Disease Metabolic Disease
Fesoterodine L-mandelate is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pK_i values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine L-mandelate is used for the overactive bladder (OAB) .

Propantheline-d3 bromide
Propantheline-d₃ (bromide) is the deuterium labeled Propantheline bromide. Propantheline bromide is an antimuscarinic agent, used for the treatment of hyperhidrosis, cramps or spasms of the stomach, intestines or bladder, and enuresis.

Clidinium-D5 bromide
Clidinium-d₅ (bromide) is the deuterium labeled Clidinium bromide. Clidinium bromide is a quaternary amine antimuscarinic agent[1].

Trospium-d8 chloride
Trospium-d₈ (chloride) is the deuterium labeled Trospium chloride. Trospium chloride is an orally active, specific and competitive antagonist of muscarinic cholinergic receptors (mAChRs), with antimuscarinic activity. Trospium chloride binds to muscarinic receptors M1, M2 and M3 with high affinity, but not nicotinic, cholinergic receptors[1][2].

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