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Results for "

antiplasmodial

" in MCE Product Catalog:

22

Inhibitors & Agonists

20

Natural
Products

Cat. No. Product Name Target Research Areas
  • HY-N7897
    Myrrhone

    Parasite Infection
    Myrrhone is a terpenoid compound with antiplasmodial effects.
  • HY-N1198
    Strictosamide

    Parasite Fungal Infection Inflammation/Immunology
    Strictosamide has important effects on inflammation and inflammatory pain. Strictosamide possesses antiplasmodial and antifungal activities.
  • HY-N5107
    Epimagnolin A

    Parasite Infection
    Epimagnolin A, a furfuran lignan, shows mild antiplasmodial activities (IC50=5.7 μg/mL) without noticeable toxicity on mammalian normal cells.
  • HY-N7985
    Pendulone

    Parasite Bacterial Cancer Infection
    Pendulone is a isoflavanquinone with good antiplasmodial activity with an IC50 of 7.0 µM. Pendulone also has antileishmanial, antibacterial and anticancer activity.
  • HY-122966
    Desmethylxanthohumol

    Apoptosis Cancer
    Desmethylxanthohumol is a prenylated hydroxychalcone isolated from hop cones (Humulus lupulus L.). Desmethylxanthohumol is a powerful apoptosis inducing agent. Desmethylxanthohumol has antiplasmodial, antiproliferative, and antioxidant bioactivities.
  • HY-133192
    Bis-propargyl-PEG3

    PROTAC Linkers Cancer Infection
    Bis-propargyl-PEG3 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG3 is used in the synthesis of zinc-dipicolylamine (ZnDPA) complexes with antiplasmodial activity .
  • HY-N7648
    Atherosperminine

    Atherospermine

    Parasite Infection
    Atherosperminine(Atherospermine)is a nature occurring alkaloid, has antiplasmodial activities in vitro, with an IC50 of 5.80 μM. Atherosperminine is a good reductant with the ability to chelate metals. Atherosperminine has scavenging activity towards the free radical DPPH, with an IC50 of 29.56 µg/mL. Atherosperminine exerts a non-specific relaxant effect on the trachealis.
  • HY-N5109
    Cheilanthifoline

    Parasite Infection
    Cheilanthifoline, an alkaloid, is isolated from Corydalis calliantha. Cheilanthifoline exhibits antiplasmodial activities against Plasmodium falciparum, with IC50s of 0.90 μg/mL and 1.22 μg/mL for wild type (TM4) and multidrug resistant (K1) strains, respectively.
  • HY-N2023A
    Thalifendine chloride

    Parasite Drug Metabolite Infection
    Thalifendine chloride is a metabolite of Berberine (HY-N0716), with antiplasmodial and antiamoebic activities. Thalifendine chloride shows activities against P. falciparum and E. histolytica with IC50s of 7.91 μM and 116 μM, respectively.
  • HY-N0749
    Jatrorrhizine

    AChE 5-HT Receptor Bacterial Neurological Disease
    Jatrorrhizine is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities. Jatrorrhizine is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115-fold selectivity for BuChE. Jatrorrhizine reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters.
  • HY-N0740
    Jatrorrhizine chloride

    AChE 5-HT Receptor Bacterial Inflammation/Immunology Neurological Disease
    Jatrorrhizine chloride is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities. Jatrorrhizine chloride is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115-fold selectivity for BuChE. Jatrorrhizine chloride reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters.
  • HY-N4307
    Laetanine

    Parasite Infection
    Laetanine, a noraporphine alkaloid from Litsea laeta, exhibits antiplasmodial activity.
  • HY-N0749A
    Jatrorrhizine hydroxide

    AChE 5-HT Receptor Bacterial Inflammation/Immunology Neurological Disease
    Jatrorrhizine hydroxide is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities. Jatrorrhizine hydroxide is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115-fold selectivity for BuChE. Jatrorrhizine hydroxide reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters.
  • HY-N6251
    Cratoxylone

    Parasite Infection
    Cratoxylone, isolated from the bark of Cratoxylum Cochinchinense, possesses antiplasmodial activity.
  • HY-N5017
    Isochondrodendrine

    Isochondrodendrin

    Parasite Infection
    Isochondrodendrine ( Isochondrodendrin) is a class of bisbenzylisoquinoline alkaloid isolated from Isolona ghesquiereina. Isochondodendrine has strong antiplasmodial activity against Plasmodium falciparum.
  • HY-132906
    Antimalarial agent 3

    Parasite Infection
    Antimalarial agent 3 shows nanomolar antiplasmodial activity (IC50 = 0.035 μM) and has a very high selectivity index with respect to mammalian cells.
  • HY-N9343
    Kulactone

    Bacterial Fungal Parasite Infection Inflammation/Immunology
    Kulactone, a natural bioflavonoid and an inhibitor against jRdRp, possesses antifungal, antibacterial and antiplasmodial activities. Kulactone exhibit no crossing through Blood Brain Barrier (BBB).
  • HY-N7016A
    Carpaine hydrochloride

    Parasite Inflammation/Immunology Cardiovascular Disease
    Carpaine hydrochloride is an alkaloid isolated from Carica papaya Linn anti-thrombocytopenic activity, exhibits potent activity in sustaining platelet counts with no acute toxicity. Carpaine hydrochloride has anti-plasmodial activity to prevent malaria.
  • HY-N7016
    Carpaine

    Parasite Inflammation/Immunology Cardiovascular Disease
    Carpaine is an alkaloid isolated from Carica papaya Linn with anti-thrombocytopenic activity, exhibits potent activity in sustaining platelet counts with no acute toxicity. Carpaine has anti-plasmodial activity to prevent malaria.
  • HY-N1581
    Quassin

    Nigakilactone D

    Parasite Infection Endocrinology
    Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits P. falciparum with an IC50 of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity.
  • HY-N5005
    Guanfu base H

    Atisinium chloride

    Parasite Infection
    Guanfu base H (Atisinium chloride) is a diterpenoid alkaloid isolated from Aconitum coreanum and has antiplasmodial activity against the malarial Plasmodium falciparum strains TM4/8.2 (wild type) and K1CB1 with IC50 values of 4 μM and 3.6 μM, respectively.
  • HY-N6009
    8-Deoxygartanin

    Parasite NF-κB Infection
    8-Deoxygartanin, a prenylated xanthones from G. mangostana, is a selective inhibitor of butyrylcholinesterase (BChE). 8-Deoxygartanin exhibits antiplasmodial activity with an IC50 of 11.8 μM for the W2 strain of Plasmodium falciparum. 8-Deoxygartanin inhibits NF-κB (p65) activation with an IC50 of 11.3 μM.