Search Result

Results for "

arrhythmic

" in MCE Product Catalog:

By Targets:	5-HT Receptor (2) Adrenergic Receptor (2) Akt (4) Autophagy (1) HIF/HIF Prolyl-Hydroxylase (1) mAChR (1) PD-1/PD-L1 (1) PI3K (4) Potassium Channel (4) Sodium Channel (7) STAT (1) Thyroid Hormone Receptor (1)
By Research Areas:	Cancer (8) Cardiovascular Disease (20) Endocrinology (1) Neurological Disease (1)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas

HY-12753A

Debutyldronedarone hydrochloride SR35021 hydrochloride	Thyroid Hormone Receptor	Cardiovascular Disease
Debutyldronedarone (SR35021) hydrochloride, the main metabolite of Dronedarone, is a selective thyroid hormone receptor α₁ (TRα₁) inhibitor. Debutyldronedarone hydrochloride inhibits T3 binding to TRα₁ and TRβ₁ by 77% and 25%, respectively. Debutyldronedarone hydrochloride can be used for the research of arrhythmic.

HY-124031

Lobetyolinin

Others Cardiovascular Disease

Lobetyolinin shows anti-arrhythmic activity.
HY-U00393

Arrhythmic-Targeting Compound 1

Others Cardiovascular Disease

Arrhythmic-Targeting Compound 1 is used for the research of arrhythmic disease, with nitrogen-containing spirocycles.
HY-U00149

Drobuline hydrochloride

Others Cardiovascular Disease

Drobuline hydrochloride is an anti-arrhythmic agent with cardiac depressant.

Lobetyolinin	Others	Cardiovascular Disease
Lobetyolinin shows anti-arrhythmic activity.

Arrhythmic-Targeting Compound 1	Others	Cardiovascular Disease
Arrhythmic-Targeting Compound 1 is used for the research of arrhythmic disease, with nitrogen-containing spirocycles.

Drobuline hydrochloride	Others	Cardiovascular Disease
Drobuline hydrochloride is an anti-arrhythmic agent with cardiac depressant.

HY-B0432AS

Propafenone D7 hydrochloride SA-79 (D7 hydrochloride)	Sodium Channel	Others
Propafenone-d₇ (hydrochloride) is the deuterium labeled Propafenone, which is a classic anti-arrhythmic agent.

HY-15551

E-4031

3 Publications Verification

Potassium Channel Cardiovascular Disease

E-4031 is a selective hERG potassium channel blocker for use in class III anti-arrhythmic studies.

E-4031 3 Publications Verification	Potassium Channel	Cardiovascular Disease
E-4031 is a selective hERG potassium channel blocker for use in class III anti-arrhythmic studies.

HY-B0432A

Propafenone hydrochloride SA-79 hydrochloride	Sodium Channel	Cardiovascular Disease
Propafenone (hydrochloride) (SA-79 (hydrochloride)) is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias.

HY-N5004

Guanfu base I Acorine	Others	Cardiovascular Disease
Guanfu base I (Acorine) is an active metabolite of Guanfu base A, isolated from Aconitum coreanum, and has a potent anti-arrhythmic effect.

HY-100635S

Diacetolol D7	Adrenergic Receptor	Endocrinology Cardiovascular Disease
Diacetolol-d₇ is a deuterium labeled Diacetolol. Diacetolol is the major metabolite of Acebutolol. Diacetolol is a β-adrenoceptor blocking and anti-arrhythmic agent[1].

HY-A0084

Procainamide hydrochloride 3 Publications Verification	Autophagy	Cancer
Procainamide hydrochloride is an anti-arrhythmic agent and is used to treat cardiac arrhythmia; induces rapid block of the batrachotoxin(BTX)-activated sodium channels of the heart muscle and acts as antagonist to long gating closures.

HY-106612

Abanoquil U-K52046; Albanoquil	Adrenergic Receptor	Cardiovascular Disease
Abanoquil (U-K52046), an potent and selective α-1 adrenoceptor antagonist, is an anti-arrhythmic agent. Abanoquil can be used for erectile dysfunction research.

HY-B0432AS2

Propafenone D5 hydrochloride	Sodium Channel	Cardiovascular Disease
Propafenone-d₅ (hydrochloride) is the deuterium labeled Propafenone hydrochloride. Propafenone (SA-79) hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias[1].

HY-B0432AS4

Propafenone-(phenyl-d5) (hydrochloride)	Sodium Channel	Cardiovascular Disease
Propafenone-(phenyl-dd₅) (hydrochloride) is the deuterium labeled Propafenone hydrochloride[1]. Propafenone hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias[2].

HY-B0432AS3

Propafenone-d5 (hydrochloride)(Ethyl)	Sodium Channel	Cardiovascular Disease
Propafenone-d₅ Ethyl (hydrochloride) is the deuterium labeled Propafenone hydrochloride. Propafenone (SA-79）hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias[1].

HY-B1167

Ajmaline Cardiorythmine; (+)-Ajmaline	Sodium Channel	Cardiovascular Disease
Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC₅₀ of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia.

HY-A0082

Diphenidol hydrochloride Difenidol hydrochloride	mAChR Sodium Channel	Neurological Disease
Diphenidol hydrochloride (Difenidol hydrochloride) is a non-selective muscarinic M₁-M₄ receptor antagonist, has anti-arrhythmic activity. Diphenidol hydrochloride is also a potent non-specific blocker of voltage-gated ion channels (Na⁺, K⁺, and Ca²⁺) in neuronal cells.

HY-A0236A

Aprindine hydrochloride	Potassium Channel	Cardiovascular Disease
Aprindine hydrochloride is a class I-b anti-arrhythmic agent and a hERG channel blocker with an IC50 of 0.23 μM. Aprindine hydrochloride has inhibitory effects on Na+/Ca2+ exchanger currents, which is partly responsible for their antiarrhythmic and cardioprotective effects. Aprindine hydrochloride is widely used for trial and ventricular tachyarrhythmias research research.

HY-B1517A

Alprenolol hydrochloride 5 Publications Verification (RS)-Alprenolol hydrochloride; dl-Alprenolol hydrochloride	5-HT Receptor	Cancer
Alprenolol ((RS)-Alprenolol; dl-Alprenolol) hydrochloride is an orally active non-selective β-adrenoceptor antagonist and an antagonist of 5-HT1A and 5-HT1B receptors. Alprenolol hydrochloride is used as an anti-hypertensive, anti-anginal and anti-arrhythmic agent.

HY-144801A

DDO-02005	Potassium Channel	Cardiovascular Disease
DDO-02005 is a potent Kv1.5 potassium channel inhibitor with an IC₅₀ value of 0.72 μM. DDO-02005 has good anti-atrial fibrillation (AF) effect in CaCl₂-ACh AF rats model and effective anti-arrhythmic activity caused by aconitine.

HY-B1517

Alprenolol 5 Publications Verification (RS)-Alprenolol; dl-Alprenolol	5-HT Receptor	Cancer
Alprenolol ((RS)-Alprenolol; dl-Alprenolol) is an orally active non-selective β-adrenoceptor antagonist and an antagonist of 5-HT1A and 5-HT1B receptors. Alprenolol is used as an anti-hypertensive, anti-anginal and anti-arrhythmic agent.

HY-N0728

α-Linolenic acid 3 Publications Verification	PI3K Akt	Cancer Cardiovascular Disease
α-Linolenic acid, isolated from Perilla frutescens, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer.

HY-144801

DDO-02005 free base	Potassium Channel	Cardiovascular Disease
DDO-02005 (free base) is a potent Kv1.5 potassium channel inhibitor with an IC₅₀ value of 0.72 μM. DDO-02005 (free base) has good anti-atrial fibrillation (AF) effect in CaCl₂-ACh AF rats model and effective anti-arrhythmic activity caused by aconitine.

HY-N0596

Panaxadiol 20(R)-Panaxadiol	PD-1/PD-L1 HIF/HIF Prolyl-Hydroxylase STAT	Cancer
Panaxadiol (20(R)-Panaxadiol) is an orally active HIF-1α/STAT3 inhibitor. Panaxadiol can suppress HIF-1α and STAT3 then lead to downregulation of programmed cell death-ligand 1 (PD-L1) expression. Panaxadiol shows anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities.

HY-N0728S

α-Linolenic acid-d5	PI3K Akt	Cancer Cardiovascular Disease
α-Linolenic acid-d₅ is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

HY-N0728S3

α-Linolenic acid-13C18	PI3K Akt	Cancer Cardiovascular Disease
α-Linolenic acid-¹³C₁₈ is the ¹³C labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

HY-N0728S2

α-Linolenic acid-d14	PI3K Akt	Cancer Cardiovascular Disease
α-Linolenic acid-d₁₄ is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

Cat. No.	Product Name	Target	Category

HY-124031

Lobetyolinin	Others	Natural Products Classification of Application Fields Disease Research Fields Cardiovascular Disease Source classification Plants other families
Lobetyolinin shows anti-arrhythmic activity.

HY-B1167

Ajmaline Cardiorythmine; (+)-Ajmaline	Sodium Channel	Indole Alkaloids Alkaloids Piperidine Alkaloids Structural Classification Apocynaceae Plants Source classification Rauvolfia serpentina Disease Research Fields Classification of Application Fields Cardiovascular Disease
Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC₅₀ of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia.

HY-N0728

α-Linolenic acid 3 Publications Verification	PI3K Akt	Structural Classification Natural Products Cardiovascular System Disorder Labiatae Endogenous metabolite Erigeron breviscapus (Vant.) Hand.-Mazz. Disease markers Plants Source classification Disease Research Fields Classification of Application Fields Cardiovascular Disease
α-Linolenic acid, isolated from Perilla frutescens, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer.

HY-N0596

Panaxadiol 20(R)-Panaxadiol	PD-1/PD-L1 HIF/HIF Prolyl-Hydroxylase STAT	Triterpenes Terpenoids Structural Classification Araliaceae Panax ginseng C. A. Meyer Plants Source classification Disease Research Fields Cancer Classification of Application Fields
Panaxadiol (20(R)-Panaxadiol) is an orally active HIF-1α/STAT3 inhibitor. Panaxadiol can suppress HIF-1α and STAT3 then lead to downregulation of programmed cell death-ligand 1 (PD-L1) expression. Panaxadiol shows anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities.

HY-N5004

Guanfu base I Acorine	Others	Indole Alkaloids Alkaloids Structural Classification Ranunculaceae Plants Source classification Aconitum coreanum (Lévl.) Rapaics Disease Research Fields Classification of Application Fields Cardiovascular Disease
Guanfu base I (Acorine) is an active metabolite of Guanfu base A, isolated from Aconitum coreanum, and has a potent anti-arrhythmic effect.

Cat. No.	Product Name

HY-B0432AS

Propafenone D7 hydrochloride

Propafenone-d₇ (hydrochloride) is the deuterium labeled Propafenone, which is a classic anti-arrhythmic agent.
HY-100635S

Diacetolol D7

Diacetolol-d₇ is a deuterium labeled Diacetolol. Diacetolol is the major metabolite of Acebutolol. Diacetolol is a β-adrenoceptor blocking and anti-arrhythmic agent[1].

Propafenone D7 hydrochloride
Propafenone-d₇ (hydrochloride) is the deuterium labeled Propafenone, which is a classic anti-arrhythmic agent.

Diacetolol D7
Diacetolol-d₇ is a deuterium labeled Diacetolol. Diacetolol is the major metabolite of Acebutolol. Diacetolol is a β-adrenoceptor blocking and anti-arrhythmic agent[1].

HY-B0432AS2

Propafenone D5 hydrochloride
Propafenone-d₅ (hydrochloride) is the deuterium labeled Propafenone hydrochloride. Propafenone (SA-79) hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias[1].

HY-B0432AS4

Propafenone-(phenyl-d5) (hydrochloride)
Propafenone-(phenyl-dd₅) (hydrochloride) is the deuterium labeled Propafenone hydrochloride[1]. Propafenone hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias[2].

HY-B0432AS3

Propafenone-d5 (hydrochloride)(Ethyl)
Propafenone-d₅ Ethyl (hydrochloride) is the deuterium labeled Propafenone hydrochloride. Propafenone (SA-79）hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias[1].

HY-N0728S

α-Linolenic acid-d5
α-Linolenic acid-d₅ is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

HY-N0728S3

α-Linolenic acid-13C18
α-Linolenic acid-¹³C₁₈ is the ¹³C labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

HY-N0728S2

α-Linolenic acid-d14
α-Linolenic acid-d₁₄ is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

arrhythmic

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
Products