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Results for "

astrocyte

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Antibiotic (3) Apoptosis (7) Aurora Kinase (3) Bacterial (3) Calcium Channel (1) Casein Kinase (1) CDK (1) Cholinesterase (ChE) (1) COX (1) Dopamine Receptor (1) EAAT (1) EGFR (2) Endogenous Metabolite (4) Estrogen Receptor/ERR (1) FAAH (1) FABP (1) Fluorescent Dye (2) GABA Receptor (1) GCGR (1) GSK-3 (5) Interleukin Related (3) Monoamine Oxidase (1) Na+/Ca2+ Exchanger (1) NF-κB (1) NO Synthase (2) P2Y Receptor (1) Phospholipase (1) Piezo Channel (2) Potassium Channel (2) PROTACs (1) Protease Activated Receptor (PAR) (2) Reactive Oxygen Species (2) Tau Protein (1) TNF Receptor (2) Trk Receptor (1) TRP Channel (2)
By Research Areas:	Cancer (7) Cardiovascular Disease (8) Infection (3) Inflammation/Immunology (12) Metabolic Disease (1) Neurological Disease (22)

By Targets:

Akt (1)

Antibiotic (3)

Apoptosis (7)

Aurora Kinase (3)

Bacterial (3)

Calcium Channel (1)

Casein Kinase (1)

CDK (1)

Cholinesterase (ChE) (1)

COX (1)

Dopamine Receptor (1)

EAAT (1)

EGFR (2)

Endogenous Metabolite (4)

Estrogen Receptor/ERR (1)

FAAH (1)

FABP (1)

Fluorescent Dye (2)

GABA Receptor (1)

GCGR (1)

GSK-3 (5)

Interleukin Related (3)

Monoamine Oxidase (1)

Na+/Ca2+ Exchanger (1)

NF-κB (1)

NO Synthase (2)

P2Y Receptor (1)

Phospholipase (1)

Piezo Channel (2)

Potassium Channel (2)

PROTACs (1)

Protease Activated Receptor (PAR) (2)

Reactive Oxygen Species (2)

Tau Protein (1)

TNF Receptor (2)

Trk Receptor (1)

TRP Channel (2)

By Research Areas:

Cancer (7)

Cardiovascular Disease (8)

Infection (3)

Inflammation/Immunology (12)

Metabolic Disease (1)

Neurological Disease (22)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Natural
Products

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101878

Texas Red 3 Publications Verification Sulforhodamine 101; SR101	Fluorescent Dye	Neurological Disease
Texas Red (Sulforhodamine 101) is an amphoteric rhodamine red fluorescent dye (excitation/emission: 586/605 nm). Texas Red is used extensively for investigating neuronal morphology and acts as acell type-selective fluorescent marker of astrocytes bothin vivoand in slice preparations .

HY-136341

7,8-Dihydroneopterin	Apoptosis NO Synthase Endogenous Metabolite	Neurological Disease Inflammation/Immunology
7,8-Dihydroneopterin, an inflammation marker, induces cellular apoptosis in astrocytes and neurons via enhancement of nitric oxide synthase (iNOS) expression. 7,8-Dihydroneopterin can be used in the research of neurodegenerative diseases .

HY-108654

PSB 0474	P2Y Receptor Apoptosis	Neurological Disease
PSB 0474 (3-phenacyl-UDP) is a selective and potent P2Y₆ receptor agonist with an EC₅₀ of 70 nM . PSB 0474 inhibits cell proliferation, increases NO release in astrocytes and microglia cells. PSB 0474 induces astrocytes apoptosis .

HY-B1558

Bifemelane MCI-2016 free base	Calcium Channel	Neurological Disease
Bifemelane is a nootropic compound. Bifemelan causes the first peak by stimulating release from intracellular Ca ²⁺ stores and the second by capacitive entry through store–operated Ca ²⁺ channels. Bifemelane will be provided as a pharmacological tool for basic studies on astrocytes .

HY-147789

FPDT	Akt	Neurological Disease Cancer
FPDT is an anti-glioblastoma agent. FPDT displays the IC₅₀ value of 45–68 μM for GBM cells and >100 μM for astrocytes. Anti-glioblastoma activity of FPDT is linked to downregulation of the AKT pathway .

HY-118207

LU-32-176B	GABA Receptor	Cancer
LU-32-176B, a GABA transporter 1(GAT1) selective inhibitor, is found to exert a synergistic anticonvulsant action with GAT2 transport inhibitor EF1502. LU-32-176B inhibits neurons, *astrocytes* and mGAT1 with the IC₅₀ values of 2μM, 1μM, 4μM, respectively .

HY-149234

MAO-B-IN-18	Monoamine Oxidase	Neurological Disease
MAO-B-IN-18 is a potent and selective MAO B inhibitor with IC₅₀s of 52 nM and 14 μM for hMAO B and hMAO A, respectively. MAO-B-IN-18 enables promising cytoprotective effects against hydrogen peroxide insults in neuroblastoma and astrocytes cultures .

HY-107661

Arundic Acid 1 Publications Verification ONO-2506; (R)-2-Propyloctanoic acid	Others	Neurological Disease
Arundic acid (ONO-2506) is an astrocyte-modulating agent, which delays the expansion of cerebral infarcts by modulating the activation of astrocytes through inhibition of S-100β synthesis. Arundic acid has the potential for stroke and Alzheimer’s disease research .

HY-100803

Hypotaurine 1 Publications Verification 2-Aminoethanesulfinic acid	Endogenous Metabolite	Neurological Disease
Hypotaurine (2-aminoethanesulfinic acid), an intermediate in taurine biosynthesis from cysteine in astrocytes, is an endogenous inhibitory amino acid of the glycine receptor. Antioxidant .

HY-121035

7BIO 7-Bromoindirubin-3-Oxime	CDK GSK-3	Neurological Disease
7BIO (7-Bromoindirubin-3-Oxime) is the derivate of indirubin. 7BIO (7-Bromoindirubin-3-Oxime) has inhibitory effects against cyclin-dependent kinase-5 (CDK5) and glycogen synthase kinase-3β (GSK3β). 7BIO (7-Bromoindirubin-3-Oxime) inhibits Aβ oligomer-induced neuroinflammation, synaptic impairments, tau hyper-phosphorylation, activation of astrocytes and microglia, and attenuates Aβ oligomer-induced cognitive impairments in mice ^[1].

HY-107661A

S-(+)-Arundic Acid (S)ONO-2506; (S)-2-Propyloctanoic acid	Others	Others
S-(+)-Arundic Acid ((S)ONO-2506) is the S-enantiomer of Arundic Acid. Arundic acid is an astrocyte-modulating agent, has the potential for stroke and Alzheimer’s disease research .

HY-N0474

Tyrosol 1 Publications Verification	NF-κB Endogenous Metabolite	Inflammation/Immunology
Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects .

HY-15515

SEA0400 15+ Cited Publications	Na+/Ca2+ Exchanger	Cardiovascular Disease
SEA0400 is a novel and selective inhibitor of the Na ⁺-Ca ²⁺ exchanger (NCX), inhibiting Na ⁺-dependent Ca ²⁺ uptake in cultured neurons, astrocytes, and microglia with IC₅₀s of from 5 to 33 nM.

HY-151919

FAAH-IN-7	FAAH	Inflammation/Immunology
FAAH-IN-7 is a reversible and potent FAAH inhibitor with an IC₅₀ value of 8.29 nM. FAAH-IN-7 suppresses oxidative stress in 1321N1 astrocytes and exhibits notable neuroprotective effect in ex vivo neuroinflammation model .

HY-N8713

4-Methyl-6-phenyl-2H-pyranone	Reactive Oxygen Species	Others
4-Methyl-6-phenyl-2H-pyranone can be used for the synthesis of N-hydroxypyridone derivatives, which can protect astrocytes against hydrogen peroxide-induced toxicity via improved mitochondrial functionality .

HY-D2155

Texas red-X 4-succinimidyl ester	Fluorescent Dye	Others
Texas red-X 4-succinimidyl ester is a derivative of Texas Red (HY-101878), an amphoteric rhodamine red fluorescent dye. Texas Red is widely used to study neuronal morphology and as a cell type-selective fluorescent marker for astrocytes, both in vivo and in slice preparations.

HY-P10019

Pegsebrenatide NLY01	GCGR	Neurological Disease
Pegsebrenatide (NLY01) is a long-acting GLP-1R agonist. Pegsebrenatide has an extended half-life and favorable blood-brain barrier penetration. Pegsebrenatide can block A1 astrocyte transformation, reducing dopaminergic cell death, and improving motor symptoms in mouse models of PD .

HY-152472

ENT-C225	Trk Receptor	Neurological Disease
ENT-C225 is an effective activator of TrkB neurotrophin receptor. ENT-C225 has high effect on activating TrkB receptor (TrkBR), and has good physicochemical properties and neuroprotective properties .

HY-10996

KHS101	Others	Neurological Disease
KHS101 is a small molecule that accelerates neuronal differentiation. KHS101 can distributes to the brain and resulted in a significant increase in neuronal differentiation .

HY-P1410

GsMTx4 Maximum Cited Publications 28 Publications Verification	TRP Channel Piezo Channel	Cardiovascular Disease Neurological Disease Inflammation/Immunology
GsMTx4 is a spider venom peptide that selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 also blocks cation-selective stretch-activated channels (SACs) , attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglial reactivity. GsMTx4 is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology .

HY-P1410A

GsMTx4 TFA Maximum Cited Publications 28 Publications Verification	TRP Channel Piezo Channel	Cardiovascular Disease Neurological Disease Inflammation/Immunology
GsMTx4 TFA is a spider venom peptide that selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 TFA also blocks cation-selective stretch-activated channels (SACs) , attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglial reactivity. GsMTx4 TFA is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology .

HY-145990

FABPs ligand 6 MF6	FABP	Inflammation/Immunology
FABPs ligand 6 (MF6) is an FABP5 and FABP7 inhibitor with K_D values of 874 nM and 20 nM, respectively. FABPs ligand 6 can be used for multiple sclerosis research .

HY-149538

TWIK-1/TREK-1-IN-3	Potassium Channel	Neurological Disease
TWIK-1/TREK-1-IN-3 (compound 2h) is an inhibitor of TWIK-related potassium channel (Potassium Channel) TREK-1. TREK-1 contains a two-pore domain potassium (K2p) channel that dimerizes into TREK-1 homodimer and TWIK-1/TREK-1 heterodimer, and is an important antidepressant target. TWIK-1/TREK-1-IN-3 targets TREK-1 homodimer and TWIK-1/TREK-1 heterodimer with IC₅₀s of 9.74 μM and 16.5 μM, respectively, and has antidepressant-like effects .

HY-113402A

Gamma-glutamylcysteine TFA γ-Glutamylcysteine TFA	Interleukin Related TNF Receptor Endogenous Metabolite	Inflammation/Immunology
Gamma-glutamylcysteine (γ-Glutamylcysteine) TFA, an intermediate in glutathione (GSH) synthesis, is a dipeptide served as an essential cofactor for the antioxidant enzyme glutathione peroxidase (GPx). Gamma-glutamylcysteine TFA also upregulates the level of the anti-inflammatory cytokine IL-10 and reduces the levels of the pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β). Gamma-glutamylcysteine TFA attenuates the changes in metalloproteinase activity in oligomeric Aβ40-treated astrocytes .

HY-14994

SCH79797 dihydrochloride 1 Publications Verification	Protease Activated Receptor (PAR) Apoptosis	Cardiovascular Disease
SCH79797 dihydrochloride is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist. SCH79797 dihydrochloride inhibits binding of a high-affinity thrombin receptor-activating peptide to PAR1 with an IC₅₀ of 70 nM and a K_i of 35 nM. SCH79797 dihydrochloride inhibits thrombin-induced platelet aggregation with an IC₅₀ of 3 μM. SCH79797 dihydrochloride has antiproliferative and pro-apoptotic effects, and limits myocardial ischemia/reperfusion injury in rat hearts. SCH79797 dihydrochloride also potently prevents PAR1 activation in vascular smooth muscle cells, endothelial cells, and astrocytes .

HY-14993

SCH79797 1 Publications Verification	Protease Activated Receptor (PAR) Apoptosis	Cardiovascular Disease
SCH79797 is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist. SCH79797 inhibits binding of a high-affinity thrombin receptor-activating peptide to PAR1 with an IC₅₀ of 70 nM and a K_i of 35 nM. SCH79797 inhibits thrombin-induced platelet aggregation with an IC₅₀ of 3 μM. SCH79797 has antiproliferative and pro-apoptotic effects, and limits myocardial ischemia/reperfusion injury in rat hearts. SCH79797 also potently prevents PAR1 activation in vascular smooth muscle cells, endothelial cells, and astrocytes .

HY-120920

UNC9995	Dopamine Receptor	Inflammation/Immunology
UNC9995 is a β-arrestin2-biased agonist of dopamine receptor Drd2. UNC9995 inhibits NLRP3 inflammasome activation by enhancing β-arrestin2-NLRP3 interaction, thus prevents neuronal degeneration. Futhermore, UNC9995 activates the Drd2/β-arrestin2 signaling to prevent inflammation-related genes transcription-induced by JAK/STAT3. UNC9995 improves depressive behavior in mouse model, and improves astrocytes dysfunctions .

HY-107521

TFB-TBOA CF3-Bza-TBOA	EAAT	Neurological Disease
TFB-TBOA (CF3-Bza-TBOA) is a potent glutamate transporter blocker that potently suppresses the activity of glial transporters. TFB-TBOA shows IC₅₀ values of 22, 17, and 300 nM for glutamate transporters EAAT1, EAAT2, and EAAT3 respectively in an uptake assay using cells transiently expressing EAATs .

HY-113489

14,15-Epoxyeicosatrienoic acid 14,15-EET	Others	Cardiovascular Disease Neurological Disease
14,15-Epoxyeicosatrienoic acid (14,15-EET) is a metabolite of Arachidonic acid (HY-109590). 14,15-Epoxyeicosatrienoic acid is a potent inhibitor of in vivo platelet aggregation. 14,15-Epoxyeicosatrienoic acid facilitates astrocytic Aβ clearance. 14,15-Epoxyeicosatrienoic acid can be used for Alzheimer's Disease research .

HY-149300

SB-1436	Cholinesterase (ChE)	Neurological Disease
SB-1436 is an Cholinesterase (ChE) inhibitor, inhibits acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and recombinant human acetylcholinesterase (rHuAChE) with IC₅₀s of 0.176, 0.37 and 0.08 μM, respectively. SB-1436 inhibits AChE and BChE in a non-competitive manner with K_is of 0.046 and 0.115 μM, respectively. SB-1436 significantly stops the self-aggregation of Aβ, and can be used for neurological disease research .

HY-N0061

Ethyl ferulate 1 Publications Verification	Reactive Oxygen Species	Neurological Disease
Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from Rhizoma Chuanxiong, induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress . Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity .

HY-130354

Dibutyryl-cGMP sodium 2 Publications Verification Bt2cGMP sodium	Potassium Channel	Cardiovascular Disease
Dibutyryl-cGMP sodium (Bt2cGMP sodium) is a cell-permeable cGMP analogue. Dibutyryl-cGMP sodium preferentially activates cGMP-dependent protein kinase (PKG). Dibutyryl-cGMP sodium inhibits the release of [ ³H]-arachidonic acid from γ thrombin-stimulated human platelets. Dibutyryl-cGMP sodium induces peripheral antinociception via activation of ATP-sensitive K ⁺ channels .

HY-101960

(Z)-Tyrphostin A51 (Z)-AG-183	EGFR	Others
(Z)-Tyrphostin A51 is the Z configuration of Lanoconazole A51. Tyrphostin A51 is a potent protein tyrosine kinase (PTK) inhibitor. Tyrphostin A51 inhibits the volume-dependent release of [ ³H]taurine in a dose-dependent manner. Tyrphostin A51 markedly reduces cellular tyrosyl phosphorylation level. Tyrphostin A51 inhibits both basal and EGF-induced human bone cell proliferation .

HY-101960A

Tyrphostin A51 AG-183	EGFR	Others
Tyrphostin A51 is a potent protein tyrosine kinase (PTK) inhibitor. Tyrphostin A51 inhibits the volume-dependent release of [ ³H]taurine in a dose-dependent manner. Tyrphostin A51 markedly reduces cellular tyrosyl phosphorylation level. Tyrphostin A51 inhibits both basal and EGF-induced human bone cell proliferation .

HY-149542

GSK-3β inhibitor 15	Tau Protein Apoptosis GSK-3	Neurological Disease
GSK-3β inhibitor 15 (Compound 54) is a GSK-3β inhibitor (IC₅₀: 3.4 nM). GSK-3β inhibitor 15 inhibits Aβ_1-42-induced GSK-3β and tau protein phosphorylation. GSK-3β inhibitor 15 inhibits LPS-induced iNOS expression. GSK-3β inhibitor 15 has neuroprotective effects on Aβ_1-42-induced neurotoxicity. GSK-3β inhibitor 15 can be used for research of Alzheimer’s disease (AD) .

HY-115498

ARN14494	Apoptosis NO Synthase Interleukin Related COX	Neurological Disease Inflammation/Immunology
ARN14494 is a potent and selective serine palmitoyltransferase (SPT) inhibitor, with an IC₅₀ of 27.3 nM. ARN14494 affects the CNS in terms of anti-inflammation and neuroprotection. ARN14494 protects neurons from β-amyloid 1-42-induced neurotoxicity through a variety of mechanisms, including anti-oxidation, anti-apoptosis, and anti-inflammation. ARN14494 can be used for Alzheimer’s disease research .

HY-B0712

Ceftriaxone 4 Publications Verification Ro 13-9904 free acid	Bacterial Antibiotic GSK-3 Aurora Kinase	Infection Inflammation/Immunology Cancer
Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC₅₀ value of 0.78 mM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .

HY-B0712A

Ceftriaxone sodium hydrate 4 Publications Verification Ro 13-9904 sodium hydrate	Bacterial Antibiotic GSK-3 Aurora Kinase	Infection Cancer
Ceftriaxone sodium hydrate (Ro 13-9904 sodium hydrate) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone sodium hydrate is a covalent inhibitor of GSK3β with IC₅₀ value of 0.78 μM. Ceftriaxone sodium hydrate is an inhibitor of Aurora B. Ceftriaxone sodium hydrate has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone sodium hydrate can be used in the study of bacterial infections and meningitis .

HY-114095

BML-280 VU0285655-1	Phospholipase TNF Receptor Interleukin Related	Metabolic Disease Inflammation/Immunology Cancer
BML-280 (VU0285655-1) is a potent and selective phospholipase D2 (PLD2) inhibitor. BML-280 has the ability to prevent caspase-3 cleavage and reduction in cell viability induced by high glucose. BML-280 can be used for rheumatoid arthritis research .

HY-149295

PROTAC ERα Degrader-4	PROTACs Estrogen Receptor/ERR Apoptosis	Cancer
PROTAC ERα Degrader-4 is a highly potent and selectivePROTAC ERα degrader (K_i: 5.08 μM). PROTAC ERα Degrader-4 contains OBHSAs, linker and E3 ligase ligands. PROTAC ERα Degrader-4 shows excellent cell inhibitory and ERα degradation activity against Tamoxifen-sensitive and -resistant ER ⁺ breast cancer (BC) cells and ERα-mutated BC cells. PROTAC ERα Degrader-4 can induce apoptosis and can be used for cancer research.

HY-B0712B

Ceftriaxone sodium salt 4 Publications Verification Ro 13-9904	Antibiotic GSK-3 Bacterial Aurora Kinase	Infection Inflammation/Immunology Cancer
Ceftriaxone sodium salt (Ro 13-9904) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone sodium salt is a covalent inhibitor of GSK3β with IC₅₀ value of 0.78 μM. Ceftriaxone sodium salt is an inhibitor of Aurora B. Ceftriaxone sodium salt has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone sodium salt can be used in the study of bacterial infections and meningitis .

HY-120267

TID43

Casein Kinase Cardiovascular Disease

TID43 is a CK2 inhibitor, with an IC₅₀ of 0.3 μM. TID43 can be used for anti-angiogenic research .

TID43	Casein Kinase	Cardiovascular Disease
TID43 is a CK2 inhibitor, with an IC₅₀ of 0.3 μM. TID43 can be used for anti-angiogenic research .

Texas Red 3 Publications Verification Sulforhodamine 101; SR101	Fluorescent Dyes/Probes
Texas Red (Sulforhodamine 101) is an amphoteric rhodamine red fluorescent dye (excitation/emission: 586/605 nm). Texas Red is used extensively for investigating neuronal morphology and acts as acell type-selective fluorescent marker of astrocytes bothin vivoand in slice preparations .

Texas red-X 4-succinimidyl ester	Fluorescent Dyes/Probes
Texas red-X 4-succinimidyl ester is a derivative of Texas Red (HY-101878), an amphoteric rhodamine red fluorescent dye. Texas Red is widely used to study neuronal morphology and as a cell type-selective fluorescent marker for astrocytes, both in vivo and in slice preparations.

Species:	Human (3) Mouse (1)
Tag:	His (3) Fc (1)
Source:	HEK293 (3) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P77296

	ARMET/MANF Protein, Mouse (HEK293, His) Mesencephalic astrocyte-derived neurotrophic factor; Arginine-rich protein; ARP	Mouse	HEK293
	ARMET/MANF proteins regulate the survival of dopaminergic neurons in the ventral midbrain and modulate GABAergic transmission to dopaminergic neurons in the substantia nigra. It enhances GABA inhibitory currents and inhibits cell proliferation while preventing ER stress-induced cell death. ARMET/MANF Protein, Mouse (HEK293, His) is the recombinant mouse-derived ARMET/MANF protein, expressed by HEK293 , with C-His labeled tag. The total length of ARMET/MANF Protein, Mouse (HEK293, His) is 179 a.a., with molecular weight of ~21 kDa.

HY-P71940A

	ARMET/MANF Protein, Human (His) Arginine rich mutated in early stage tumors; Arginine rich protein; Arginine-rich protein; ARMET; ARMET protein; ARP; Manf; MANF_HUMAN; Mesencephalic astrocyte derived neurotrophic factor; Mesencephalic astrocyte-derived neurotrophic factor; MGC142148; MGC142150; Protein ARMET	Human	E. coli
	ARMET/MANF proteins critically support the survival of dopaminergic neurons in the ventral midbrain and contribute to neuronal homeostasis. It modulates GABAergic transmission and enhances inhibitory postsynaptic currents in substantia nigra dopaminergic neurons. ARMET/MANF Protein, Human (His) is the recombinant human-derived ARMET/MANF protein, expressed by E. coli , with N-6*His labeled tag. The total length of ARMET/MANF Protein, Human (His) is 158 a.a., with molecular weight of ~20 kDa.

HY-P76731

	ARMET/MANF Protein, Human (HEK293, Fc) Mesencephalic astrocyte-derived neurotrophic factor; Arginine-rich protein; ARP	Human	HEK293
	ARMET/MANF Protein is an evolutionary conserved endoplasmic reticulum stress- (ERS-) related protein. ARMET/MANF has a protective effect on central nervous system diseases and plays an important role in several metabolic diseases. It is mainly localized to the luminal endoplasmic reticulum (ER) as an ER chaperone protein, mainly interacting with BiP and Reticulon 1-C. Meanwhile, MANF can prevent ER stress-mediated cell death in neurons and other tissues. ARMET/MANF Protein, Human (HEK293, Fc) is the recombinant human-derived ARMET/MANF protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ARMET/MANF Protein, Human (HEK293, Fc) is 182 a.a., with molecular weight of ~44.9 KDa.

HY-P7605

	ARMET/MANF Protein, Human (158a.a, HEK293, His) rHuARMET/MANF, His; Mesencephalic astrocyte-derived neurotrophic factor; ARMET	Human	HEK293
	ARMET/MANF Protein, Human (158a.a, HEK293, His) expresses in HEK293 cells with a His tag. Armet/MANF, localized in the ER and Golgi, is a secreted protein and acts as a gene up-regulated by various forms of ER stress.

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