2. Search Result
Search Result
Results for "

bicuculline

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0219
    Bicuculline
    Maximum Cited Publications
    20 Publications Verification

    (+)-bicuculline; d-bicuculline

    		 GABA Receptor Neurological Disease
    Bicuculline ((+)-Bicuculline) is A competing neurotransmitter GABAA receptor antagonist (IC50=2 μM). Bicuculline also blocks Ca 2+ activating potassium (SK) channels and subsequently blocks slow post-hyperpolarization (slow AHP). Bicuculline has anticonvulsant activity. Bicuculline can be used to induce seizures in mice .
    <em>Bicuculline</em>
  • HY-103474
    Bicuculline methiodide

    (+)-bicuculline methiodide; d-bicuculline methiodide

    		 GABA Receptor Neurological Disease
    Bicuculline methiodide is a potent GABA(A) receptors blocker. Bicuculline methiodide alters membrane properties and firing pattern. Bicuculline methiodide reduces the Apamin-sensitive afterhyperpolarization, while Apamin is a toxin isolated from bee venom to block small conductance Ca 2+ -activated K + channels. Bicuculline methiodide facilitates burst firing via blocking apamin-sensitive Ca 2+ -activated K + current .
    <em>Bicuculline</em> methiodide
  • HY-100783
    (-)-Bicuculline methobromide

    l-bicuculline methobromide
    (-)-Bicuculline methobromide (l-Bicuculline methobromide) is a potent GABAA receptor antagonist. (-)-Bicuculline methobromide blocks afterhyperpolarizations (AHPs) mediated by Ca 2+-activated K + channels in various types of neurons .
    (-)-<em>Bicuculline</em> methobromide
  • HY-137790
    Bicuculline methochloride

    (+)-bicuculline methochloride; d-bicuculline methochloride

    		 GABA Receptor Neurological Disease
    Bicuculline ((+)-Bicuculline; d-Bicuculline) methochloride is a selective GABAA receptor antagonist with an IC50 value of 3 μM. Bicuculline methochloride induces clonic tonic convulsions in mammals and can also be used to block Ca 2+ activated potassium channels. Bicuculline methochloride can be used in studies of epilepsy and other related psychiatric disorders .
    <em>Bicuculline</em> methochloride
  • HY-100783A
    (-)-Bicuculline methochloride

    l-bicuculline methochloride
    (-)-Bicuculline methochloride (l-Bicuculline methochloride) is a potent GABAA receptor antagonist. (-)-Bicuculline methochloride blocks afterhyperpolarizations (AHPs) mediated by Ca 2+-activated K + channels in various types of neurons .
    (-)-<em>Bicuculline</em> methochloride
  • HY-100783B
    Bicuculline methobromide

    (+)-bicuculline methobromide; d-bicuculline methobromide

    		 GABA Receptor Neurological Disease
    Bicuculline methobromide is a selective GABAA Receptor antagonist with an IC50 value of 3 μM. Bicuculline methobromide induces clonic tonic convulsions in mammals and can also be used to block Ca 2+ activated potassium channels. Bicuculline methobromide can be used in studies of epilepsy and other related psychiatric disorders .
    <em>Bicuculline</em> methobromide
  • HY-123478
    Fengabine

    SL 79229

    		 GABA Receptor Neurological Disease
    Fengabine is a GABAergic antidepressant agent. Fengabine can be used for the research of depression .
    Fengabine
  • HY-100798
    Phaclofen

    Phaclofen is a selective GABAB receptor antagonist. Phaclofen is a peripheral and central baclofen antagonist. Phaclofen maybe a potential compound in determining the physiological significance of central and peripheral bicuculline-insensitive receptors with which GABA and (-)-baclofen interact .
    Phaclofen

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: