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blast

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (3) CRM1 (1) DNA/RNA Synthesis (3) Fungal (6) Isocitrate Dehydrogenase (IDH) (1) MDM-2/p53 (1) STAT (1)
By Research Areas:	Cancer (7) Infection (6)

Inhibitors & Agonists

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-16271

Kevetrin hydrochloride 4-Isothioureidobutyronitrile hydrochloride; thioureidobutyronitrile hydrochloride; thioureido butyronitrile hydrochloride	MDM-2/p53 Apoptosis	Cancer
Kevetrin hydrochloride is a potent activator of p53, induces apoptosis in TP53 wild-type and mutant acute myeloid leukemia cells. Kevetrin a preferential cytotoxic activity against blast cells .

HY-111968

Orysastrobin	Fungal	Infection
Orysastrobin, a “quinone outside inhibitor” (QoI)-type fungicide, has excellent fungicidal efficacy against leaf and panicle blast and against sheath blight in rice .

HY-B1863

Iprobenfos

Fungal Infection

Iprobenfos is an organophosphorus fungicide and is widely used to control the rice blast fungus. Iprobenfos is also a choline biosynthesis inhibitor .

Iprobenfos	Fungal	Infection
Iprobenfos is an organophosphorus fungicide and is widely used to control the rice blast fungus. Iprobenfos is also a choline biosynthesis inhibitor .

HY-W075256

Isotianil	Others	Others
Isotianil is a plant defense inducer that has no direct antimicrobial effect but instead activates typical plant defense responses. Isotianil can be used as a plant protection agent for controlling rice blast .

HY-N2646

5-Heptadec-cis-8-enylresorcinol	Fungal	Infection
5-Heptadec-cis-8-enylresorcinol is a 5-alkylresorcinol that can be isolated from etiolated rice seedlings. 5-Heptadec-cis-8-enylresorcinol is an antifungal agent against the rice blast fungus. 5-Heptadec-cis-8-enylresorcinol mediates DNA relaxation .

HY-N8615

Peucedanocoumarin II

Others Others

Peucedanocoumarin II can induce rice resistance to blast disease .

Peucedanocoumarin II	Others	Others
Peucedanocoumarin II can induce rice resistance to blast disease .

HY-128888B

(S,R)-GSK321	Isocitrate Dehydrogenase (IDH)	Cancer
(S,R)-GSK321 is a potent, selective mutant IDH1 inhibitor with IC₅₀ values of 2.9, 3.8, 4.6 and 46 nM for R132G, R132C, R132H and WT IDH1, respectively, and >100-fold selectivity over IDH2. (S,R)-GSK321 induces decrease in intracellular 2-HG, abrogation of the myeloid differentiation block and induction of granulocytic differentiation at the level of leukemic blasts and more immature stem-like cells. (S,R)-GSK321can be used for research of acute myeloid leukemia (AML) and other cancers .

HY-B1858

Isoprothiolane	Fungal	Infection
Isoprothiolane is a systemic fungicide. Isoprothiolane is a rice blast controlling agent against the fungal disease of rice planty Pyvioutavia oryzae Cav .

HY-115740

Cytarabine triphosphate Ara-CTP	DNA/RNA Synthesis	Cancer
Cytarabine triphosphate (Ara-CTP), an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine .

HY-115740A

Cytarabine triphosphate trisodium Ara-CTP trisodium	DNA/RNA Synthesis	Cancer
Cytarabine triphosphate (Ara-CTP) trisodiu, an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate trisodiu levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine .

HY-B1858S

Isoprothiolane-d4	Fungal	Infection
Isoprothiolane-d₄ is the deuterium labeled Isoprothiolane. Isoprothiolane is a systemic fungicide. Isoprothiolane is a rice blast controlling agent against the fungal disease of rice planty Pyvioutavia oryzae Cav[1][2].

HY-15611

KPT-185	CRM1	Cancer
KPT-185 is an orally bioavailable and selective inhibitor of CRM1 and displays potent antiproliferative properties at submicromolar concentrations (IC₅₀=100-500 nM), induces apoptosis, cell-cycle arrest, and myeloid differentiation in AML cell lines and patient blasts .

HY-P1923

L-Asparaginase 5+ Cited Publications L-ASNase	Apoptosis DNA/RNA Synthesis	Cancer
L-Asparaginase (L-ASNase) is a deamidating enzyme that catalyses the hydrolysis of L-asparagine and L-glutamine, and can be used for the research of acute lymphoblastic leukemia. L-Asparaginase depletes L-asparagine from plasma resulting in inhibition of RNA and DNA synthesis with the subsequent blastic cell apoptosis .

HY-N3570

Cerebroside B

Fungal Infection

Cerebroside B, a sphingolipid compound, is a non-racespecific elicitor, which elicits defense responses in rice .

Cerebroside B	Fungal	Infection
Cerebroside B, a sphingolipid compound, is a non-racespecific elicitor, which elicits defense responses in rice .

HY-112288

C188-9 15+ Cited Publications TTI-101	STAT Apoptosis	Cancer
C188-9 (TTI-101) is a STAT3 inhibitor, with a K_d of 4.7 nM. C188-9 inhibits G-CSF-induced STAT3 activation and STAT3-dependent gene expression. C188-9 induces apoptosis in AML cell lines and primary samples and inhibits colony formation by primary AML blasts .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N3570

Cerebroside B	Infection Natural Products Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Fungal
Cerebroside B, a sphingolipid compound, is a non-racespecific elicitor, which elicits defense responses in rice .

HY-N2646

5-Heptadec-cis-8-enylresorcinol	Structural Classification Source classification Phenols Polyphenols Proteaceae Plants Hakea amplexicaulis R.Br.	Fungal
5-Heptadec-cis-8-enylresorcinol is a 5-alkylresorcinol that can be isolated from etiolated rice seedlings. 5-Heptadec-cis-8-enylresorcinol is an antifungal agent against the rice blast fungus. 5-Heptadec-cis-8-enylresorcinol mediates DNA relaxation .

HY-N8615

Peucedanocoumarin II	Chrysanthemum × morifolium (Ramat.) Hemsl. Classification of Application Fields Source classification Other Diseases Coumarins Phenylpropanoids Plants Umbelliferae Disease Research Fields	Others
Peucedanocoumarin II can induce rice resistance to blast disease .

Species:	Human (4) Mouse (3) Rat (3)
Tag:	His (5) Fc (5)
Source:	HEK293 (10)

Cat. No.	Compare	Product Name	Species	Source

HY-P72022

	SLAMF2/CD48 Protein, Human (HEK293, hFc) B-lymphocyte activation marker blast-1 BCM1 surface antigen; Leukocyte antigen MEM-102; SLAM family member 2; SLAMF2; Signaling lymphocytic activation molecule 2; TCT.1; CD48; BCM1; blast1;	Human	HEK293
	SLAMF2/CD48 protein is a GPI-anchored glycoprotein that regulates immune cell function by interacting with CD2 and CD244. SLAMF2/CD48 Protein, Human (HEK293, hFc) is the recombinant human-derived SLAMF2/CD48 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of SLAMF2/CD48 Protein, Human (HEK293, hFc) is 194 a.a., with molecular weight of ~66 kDa.

HY-P72466

	SLAMF2/CD48 Protein, Mouse (194a.a, HEK293, His) CD48; blast1; BCM1; SLAMF2; SLAM Family Member 2	Mouse	HEK293
	SLAMF2/CD48 protein is a GPI-anchored glycoprotein that regulates immune cell function by interacting with CD2 and CD244. SLAMF2/CD48 Protein, Mouse (194a.a, HEK293, His) is the recombinant mouse-derived SLAMF2/CD48 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of SLAMF2/CD48 Protein, Mouse (194a.a, HEK293, His) is 194 a.a., with molecular weight of 45-50 kDa.

HY-P71091

	SLAMF2/CD48 Protein, Human (HEK293, mFc) CD48 antigen; B-lymphocyte activation marker blast-1; BCM1 surface antigen; Leukocyte antigen MEM-102; TCT.1; CD48; BCM1; blast1	Human	HEK293
	SLAMF2/CD48 protein is a GPI-anchored glycoprotein that regulates immune cell function by interacting with CD2 and CD244. SLAMF2/CD48 Protein, Human (HEK293, mFc) is the recombinant human-derived SLAMF2/CD48 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of SLAMF2/CD48 Protein, Human (HEK293, mFc) is 194 a.a., with molecular weight of 60-80 kDa.

HY-P72919

	SLAMF2/CD48 Protein, Human (HEK293, His) CD48 antigen; SLAMF2; TCT.1; CD48; BCM1; blast1	Human	HEK293
	SLAMF2/CD48 protein is a GPI-anchored glycoprotein that regulates immune cell function by interacting with CD2 and CD244. SLAMF2/CD48 Protein, Human (HEK293, His) is the recombinant human-derived SLAMF2/CD48 protein, expressed by HEK293 , with C-His labeled tag. The total length of SLAMF2/CD48 Protein, Human (HEK293, His) is 194 a.a., with molecular weight of ~40 kDa.

HY-P74541

	SLAMF2/CD48 Protein, Rat (HEK293, His) CD48 antigen; SLAMF2; TCT.1; CD48; BCM1; blast1	Rat	HEK293
	SLAMF2/CD48 is a GPI-anchored glycoprotein that regulates immune cells. It interacts with receptors like CD2 and CD244/2B4, activating LCK and LAT in T-cell signaling. SLAMF2 also phosphorylates CD244, leading to immunological synapse formation and targeted release of cytolytic granules by T-lymphocytes and NK-cells. Its direct interactions with CD2, CD244, and LCK contribute to immune response regulation. SLAMF2/CD48 Protein, Rat (HEK293, His) is the recombinant rat-derived SLAMF2/CD48 protein, expressed by HEK293 , with C-His labeled tag. The total length of SLAMF2/CD48 Protein, Rat (HEK293, His) is 194 a.a., with molecular weight of 32-50 kDa.

HY-P74542

	SLAMF2/CD48 Protein, Rat (HEK293, hFc) CD48 antigen; SLAMF2; TCT.1; CD48; BCM1; blast1	Rat	HEK293
	SLAMF2/CD48 is a GPI-anchored glycoprotein that regulates immune cells. It interacts with receptors like CD2 and CD244/2B4, activating LCK and LAT in T-cell signaling. SLAMF2 also phosphorylates CD244, leading to immunological synapse formation and targeted release of cytolytic granules by T-lymphocytes and NK-cells. Its direct interactions with CD2, CD244, and LCK contribute to immune response regulation. SLAMF2/CD48 Protein, Rat (HEK293, hFc) is the recombinant rat-derived SLAMF2/CD48 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of SLAMF2/CD48 Protein, Rat (HEK293, hFc) is 216 a.a., with molecular weight of 38-44 kDa.

HY-P74320

	CD23/Fc epsilon RII Protein, Rat (HEK293, Fc) Low affinity immunoglobulin epsilon Fc receptor; blast-2; FCER2; CD23A	Rat	HEK293
	CD23, also known as Fc epsilon Receptor II (Fc epsilon RII), is a low-affinity receptor for immunoglobulin E (IgE) and complement receptor 2 (CR2/CD21). CD23 regulates IgE production and B-cell differentiation, aiding in IGE-dependent antigen uptake. CD23/Fc epsilon RII Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD23/Fc epsilon RII protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CD23/Fc epsilon RII Protein, Rat (HEK293, Fc) is 282 a.a., with molecular weight of 60-75 kDa.

HY-P74321

	CD23/Fc epsilon RII Protein, Mouse (HEK293, His) Low affinity immunoglobulin epsilon Fc receptor; blast-2; FCER2; CD23A	Mouse	HEK293
	CD23/Fc epsilon RII Protein, a low-affinity receptor for IgE and CR2/CD21, regulates IgE production and B cell differentiation. On B cells, it initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, IgE binding induces intracellular killing of parasites through the L-Arginine-nitric oxide pathway. CD23/Fc epsilon RII homotrimer interacts with IGHE to regulate IgE homeostasis and with CR2/CD21 for binding. CD23/Fc epsilon RII Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD23/Fc epsilon RII protein, expressed by HEK293 , with N-His labeled tag. The total length of CD23/Fc epsilon RII Protein, Mouse (HEK293, His) is 282 a.a., with molecular weight of 33-43 kDa.

HY-P74543

	SLAMF2/CD48 Protein, Mouse (216a.a, HEK293, Fc) CD48 antigen; SLAMF2; TCT.1; CD48; BCM1; blast1	Mouse	HEK293
	CD48 (SLAMF2) is a member of the CD2 subfamily of immunoglobulin-like receptors, it is held at the cell surface by a Glycosylphosphatidylinositol GPI anchor via a C-terminal domain, and interacts with cell surface receptors including 2B4/CD244 or CD2 via its N-terminal immunoglobulin domain to activate the LCK pathway and regulate immune cell function and activation. SLAMF2/CD48 Protein, Mouse (216a.a, HEK293, Fc) is the recombinant mouse-derived SLAMF2/CD48 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of SLAMF2/CD48 Protein, Mouse (216a.a, HEK293, Fc) is 216 a.a., with molecular weight of ~63.7 kDa.

HY-P72748

	CD23/Fc epsilon RII Protein, Human (HEK293, His) Low affinity immunoglobulin epsilon Fc receptor; blast-2; FCER2; CD23A; CLEC4J; FCE2; IGEBF	Human	HEK293
	CD23 or Fc epsilon receptor II (Fc epsilon RII) is a low-affinity receptor for immunoglobulin E (IgE) and complements receptor 2 (CR2/CD21). CD23 is present on B cells, regulates IgE production and B cell differentiation, and aids in IgE-dependent antigen uptake. CD23/Fc epsilon RII Protein, Human (HEK293, His) is the recombinant human-derived CD23/Fc epsilon RII protein, expressed by HEK293 , with N-8*His labeled tag. The total length of CD23/Fc epsilon RII Protein, Human (HEK293, His) is 274 a.a., with molecular weight of 35-40 kDa.


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Cat. No.	Product Name	Chemical Structure

HY-B1858S

Isoprothiolane-d4
Isoprothiolane-d₄ is the deuterium labeled Isoprothiolane. Isoprothiolane is a systemic fungicide. Isoprothiolane is a rice blast controlling agent against the fungal disease of rice planty Pyvioutavia oryzae Cav[1][2].

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blast

Inhibitors & Agonists

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Natural
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