burn

By Targets:	5-HT Receptor (1) Antibiotic (4) Bacterial (5) DNA/RNA Synthesis (1) Influenza Virus (1) Isotope-Labeled Compounds (1) Prostaglandin Receptor (2) Protease Activated Receptor (PAR) (2)
By Research Areas:	Cancer (1) Endocrinology (1) Infection (7) Inflammation/Immunology (5) Metabolic Disease (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-102065

SC-19220	Prostaglandin Receptor	Others
SC-19220 is a competitive prostaglandinn E2 receptor antagonist. SC-19220 increases the bladder capacity and reduced the voiding efficiency of micturition (elicited by slow transvesical filling) of urethane-anesthetized rats. SC-19220 can restores the balance in bone marrow granulocyte and monocyte production after burn sepsis .

HY-101482

Ibuprofen piconol U75630	Others	Inflammation/Immunology
Ibuprofen piconol is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.

HY-W014750

3-Acetamidocoumarin	Others	Inflammation/Immunology Cancer
3-Acetamidocoumarin plays an important role in biology and medicine. 3-Acetamidocoumarin has physiological effects and has been used for many diseases such as research of burns, brucellosis-rheumatic diseases and cancer .

HY-105052

SC 34301 Enisoprost	Prostaglandin Receptor	Endocrinology
SC 34301 (Enisoprost) is a potent and orally active PGE1 analog. SC 34301 significantly reduces bacterial translocation and improves survival for burned mice .

HY-B0614

Mafenide	Bacterial Antibiotic	Infection
Mafenide is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide shows activity against both Gram-positive and Gram-negative organisms, including *Pseudomonas aeruginosa*, via inhibition of nucleotide synthesis .

HY-B0614A

Mafenide Acetate	Bacterial Antibiotic	Infection
Mafenide Acetate is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide Acetate shows activity against both Gram-positive and Gram-negative organisms, including *Pseudomonas aeruginosa*, via inhibition of nucleotide synthesis .

HY-B0614B

Mafenide hydrochloride	Bacterial Antibiotic	Infection
Mafenide hydrochloride is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide hydrochloride shows activity against both Gram-positive and Gram-negative organisms, including *Pseudomonas aeruginosa*, via inhibition of nucleotide synthesis .

HY-151164

LasR-IN-2	Bacterial	Infection
LasR-IN-2 is a LasR inhibitor that forms H-bonding with TRY-56 residue. LasR-IN-2 can be used in the research of bacterial infection, neutropenia, severe burns and chronic lung disease in cystic fibrosis (CF) .

HY-B0226S

Nitrofurazone-13C,15N2 Nitrofural-¹³C,¹⁵N₂	Isotope-Labeled Compounds	Infection
Nitrofurazone- ¹³C, ¹⁵N₂ (Nitrofural- ¹³C, ¹⁵N₂) is the ¹³C and ¹⁵N labled Nitrofurazone (HY-B0226) . Nitrofurazone is a potential antibiotic that can be used topically to treat wounds, burns, ulcers and skin infections to combat various microorganisms and to prepare surfactants . Nitrofurazone may affect the ecosystem function in Marine environment and affect the functional processes of epiphytic fauna .

HY-B1497

Silver sulfadiazine AgSD	Bacterial DNA/RNA Synthesis Antibiotic	Infection
Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication .

HY-100943

Cinanserin hydrochloride 1 Publications Verification SQ 10643	5-HT Receptor Influenza Virus	Infection Inflammation/Immunology
Cinanserin hydrochloride (SQ 10643) is a potent, selective and highly affinity 5-HT₂ receptor antagonist with a K_i of 41 nM. Cinanserin hydrochloride has a much higher binding affinity for the 5-HT₂ than for the 5-HT₁ receptor (K_i of 3500 nM). Cinanserin is also an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro .

HY-P1263

tcY-NH2 (trans-Cinnamoyl)-YPGKF-NH2	Protease Activated Receptor (PAR)	Metabolic Disease Inflammation/Immunology
tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) is a potent selective PAR4 antagonist peptide. tcY-NH2 inhibits thrombin- and AY-NH₂-induced platelet aggregation and endostatin release, and can be used in the research of inflammation, immunology .

HY-P1263A

tcY-NH2 TFA 1 Publications Verification (trans-Cinnamoyl)-YPGKF-NH2 TFA	Protease Activated Receptor (PAR)	Metabolic Disease Inflammation/Immunology
tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) TFA is a potent selective PAR4 antagonist peptide. tcY-NH2 TFA inhibits thrombin- and AY-NH₂-induced platelet aggregation and endostatin release, and can be used in the research of inflammation, immunology .

Cat. No.	Product Name	Type

HY-107940

Sutilains

Biochemical Assay Reagents

Sutilains is a proteolytic enzyme that dissolves necrotic tissue and hyaluronidase. Sutilains can be used as a topical debriding agent in burns .

Sutilains	Biochemical Assay Reagents
Sutilains is a proteolytic enzyme that dissolves necrotic tissue and hyaluronidase. Sutilains can be used as a topical debriding agent in burns .

Cat. No.	Product Name	Target	Research Area

HY-P1263A

tcY-NH2 TFA 1 Publications Verification (trans-Cinnamoyl)-YPGKF-NH2 TFA	Protease Activated Receptor (PAR)	Metabolic Disease Inflammation/Immunology
tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) TFA is a potent selective PAR4 antagonist peptide. tcY-NH2 TFA inhibits thrombin- and AY-NH₂-induced platelet aggregation and endostatin release, and can be used in the research of inflammation, immunology .

HY-P1263

tcY-NH2 (trans-Cinnamoyl)-YPGKF-NH2	Protease Activated Receptor (PAR)	Metabolic Disease Inflammation/Immunology
tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) is a potent selective PAR4 antagonist peptide. tcY-NH2 inhibits thrombin- and AY-NH₂-induced platelet aggregation and endostatin release, and can be used in the research of inflammation, immunology .

Cat. No.	Product Name	Chemical Structure

HY-B0226S

Nitrofurazone-13C,15N2
Nitrofurazone- ¹³C, ¹⁵N₂ (Nitrofural- ¹³C, ¹⁵N₂) is the ¹³C and ¹⁵N labled Nitrofurazone (HY-B0226) . Nitrofurazone is a potential antibiotic that can be used topically to treat wounds, burns, ulcers and skin infections to combat various microorganisms and to prepare surfactants . Nitrofurazone may affect the ecosystem function in Marine environment and affect the functional processes of epiphytic fauna .

Nitrofurazone-13C,15N2

Nitrofurazone- ¹³C, ¹⁵N₂ (Nitrofural- ¹³C, ¹⁵N₂) is the ¹³C and ¹⁵N labled Nitrofurazone (HY-B0226) . Nitrofurazone is a potential antibiotic that can be used topically to treat wounds, burns, ulcers and skin infections to combat various microorganisms and to prepare surfactants . Nitrofurazone may affect the ecosystem function in Marine environment and affect the functional processes of epiphytic fauna .

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