Search Result
Results for "
carbamate
" in MedChemExpress (MCE) Product Catalog:
7
Biochemical Assay Reagents
13
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-Y1401S
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- HY-133776
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3-Nitrophenyl ethyl(methyl)carbamate
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Cholinesterase (ChE)
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Neurological Disease
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Rivastigmine carbamate impurity (3-Nitrophenyl ethyl(methyl)carbamate) is an impurity of Rivastigmine. Rivastigmine is an orally active and potent cholinesterase (ChE) inhibitor and inhibits butyrylcholinesterase (BChE) and acetylcholinesteras (AChE) with IC50s of 0.037 μM, 4.15 μM, respectively .
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- HY-151877S
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- HY-101831
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- HY-W098764
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ADC Linker
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Others
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Allyl (2-aminoethyl)carbamate hydrochloride is a cleavable linker.
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- HY-145735
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- HY-156513
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ADC Cytotoxin
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Cancer
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7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin) is a Camptothecin (HY-16560) analogue. 7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin) is a ADC cytotoxin that can be used for synthesis of ADCs, and for cancer research .
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- HY-107944
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Maolate; U 19646
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Others
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Neurological Disease
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Chlorphenesin carbamate is a centrally acting skeletal muscle relaxant. Chlorphenesin carbamate can be used for the research of pain and discomfort related to skeletal muscle trauma and inflammation . Chlorphenesin carbamate is a selective blocker of polysynaptic pathways at the spinal and supra-spinal levels . Antinociceptive effect .
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- HY-138885
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TpGc
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Others
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Neurological Disease
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Tryptamine guanosine carbamate (TpGc) is a selective HINT1 (histidine triad nucleotide-binding protein 1) inhibitor (Ki=34 μM, Kd=3.65 μM). Tryptamine guanosine carbamate significantly enhances morphine antinociception while preventing the development of tolerance .
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- HY-W127396
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Biochemical Assay Reagents
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Others
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Cholesteryl N-(trimethylammonioethyl)carbamate chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-40172
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Biochemical Assay Reagents
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Others
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tert-Butyl (3-aminopropyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W016730S
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- HY-147053
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Others
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Others
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2-(Diethylamino)ethyl (3-(octyloxy)phenyl)carbamate hydrochloride is a small molecule compound.
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- HY-34346
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[[[Hydrazino]carbonyl]methyl]carbamic acid tert-butyl ester; tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate; tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate
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tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate is a Glycine (HY-Y0966) derivative .
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- HY-B0830S
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- HY-B1207
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Ethyl carbamate; Carbamic acid ethyl ester; Ethylurethane
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Bacterial
Parasite
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Infection
Neurological Disease
Cancer
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Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .
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- HY-149037
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N4-Spermine cholesteryl carbamate
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Liposome
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Others
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GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
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- HY-153117
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Others
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Others
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Cyclohexyl [3,5-bis(methylthio)-4-isothiazolyl]carbamate is a compound that can be used for altering the lifespan of eukaryotic organisms .
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- HY-121558
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- HY-117695
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AQC
2 Publications Verification
6-Aminoquinolyl-N-hydroxysccinimidyl carbamate
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Fluorescent Dye
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Others
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AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels .
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- HY-149037A
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N4-Spermine cholesteryl carbamate pentahydrochloride
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Liposome
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Others
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GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
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- HY-30120
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Biochemical Assay Reagents
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Others
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tert-Butyl N-[(1S,2S)-2-aminocyclohexyl]carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-119419
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Cholinesterase (ChE)
Parasite
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Neurological Disease
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Pirimicarb is a fast-acting selective carbamate insecticide on a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables. Pirimicarb is an AChE inhibitor and an acaricide .
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- HY-122832
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Wnt
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Cancer
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ABC99 is an N-hydroxyhydantoin (NHH) carbamate that selectively inhibits the Wnt-deacylating enzyme NOTUM (IC50=13 nM). ABC99 preserves Wnt3A signaling in the presence of NOTUM .
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- HY-143419
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Phosphodiesterase (PDE)
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Inflammation/Immunology
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ATX inhibitor 14 (compound 4), a indole-based carbamate derivative, is a potent autotaxin (ATX) inhibitor with an IC50 of 0.41 nM. ATX inhibitor 14 has the potential for fibrosis relevant diseases research .
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- HY-B0835S
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Apoptosis
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Neurological Disease
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Fenobucarb-d3 is the deuterium labeled Fenobucarb. Fenobucarb is a carbamate insecticide. Fenobucarb induces zebrafish developmental neurotoxicity through pathways involved in inflammation, oxidative stress, degeneration and apoptosis[1].
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- HY-B1207S
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Ethyl carbamate-d5; Carbamic acid ethyl ester-d5; Ethylurethane-d5
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Bacterial
Parasite
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Infection
Neurological Disease
Cancer
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Urethane-d5 is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro[1].
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- HY-143420
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Phosphodiesterase (PDE)
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Inflammation/Immunology
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ATX inhibitor 15 (compound 30), a indole-based carbamate derivative, is a potent autotaxin (ATX) inhibitor with an IC50 of 2.17 nM. ATX inhibitor 15 inhibits in vivo ATX and the gene expression of pro-fibrotic factors. ATX inhibitor 15 has lung protection effects in Bleomycin challenged mice lung fibrosis model .
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- HY-D1258
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VDP-green
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Fluorescent Dye
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Others
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AC-green (VDP-green) is a β-allyl carbamate fluorescent probe for specifically imaging vicinal dithiol proteins (VDPs) in living systems (λex/λem=400/475 nm). AC-green can detect the reduced bovine serum albumin (rBSA) with high sensitivity. AC-green displays low toxicity and features high sensitivity, and is suitable for sensing VDPs in living cells and zebrafishes .
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- HY-B2032
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Phenmedipham is a carbamate herbicide .
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- HY-153804
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NCD
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Molecular Glues
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Others
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Naphthyridine caebamate dimer (NCD) is a DNA molecular glue that induces designed structural changes in target functional DNA to modulate function .
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- HY-117870
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- HY-18080
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- HY-W059342S
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- HY-17530
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Cholinesterase (ChE)
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Others
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Aldicarb sulfone(Temik sulfone) is a carbamate insecticide; is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse.
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- HY-121267S1
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- HY-B0916
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Fungal
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Infection
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Propoxur is a carbamate insecticide with a fast knockdown and long residual effect used against turf, forestry, and household pests and fleas.
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- HY-B0830
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Isoprocarb is carbamate insecticide that widely used to control rice paddy lice and leafhopper. Isoprocarb is also an AChE inhibitor .
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- HY-111202
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- HY-N3162
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Others
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Others
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Obtucarbamate B is a carbamate derivative, that can be isolated from the South China Sea gorgonian coral Melitodes squamata Nutting .
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- HY-N9349
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- HY-139143
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FAAH
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Others
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WWL154, an analog of JZL184 that maintains the SH-reactive p-nitrophenyl carbamate group, is a FAAH-4 inhibitor .
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- HY-W014240
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Others
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Others
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Chlorpropham is a carbamate herbicide and plant growth regulator. Chlorpropham inhibits mitosis and cell division by interfering with the organisation of the spindle microtubules .
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- HY-40174A
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Biochemical Assay Reagents
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Others
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tert-Butyl (2-aminoethyl)(methyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W013767
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Others
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Infection
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Thiodicarb is a carbamate insecticide used to control flies in animal and poultry houses and dairies. Thiodicarb is metabolized into methomyl in animals and plants, and subsequently degraded into carbon dioxide and acetonitrile .
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- HY-116482
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Others
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Others
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Desmedipham is a selective systemic phenyl-carbamate herbicide. Desmedipham acts by disrupting CO2 fixation and the production of intermediary energy components-ATP and NADPH2 and inhibition of Hill reaction .
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- HY-B1198
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ENT-14250
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Parasite
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Infection
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Piperonyl butoxide is a semi-synthetic derivative of safrole used as a component of pesticide formulations. It is a synergist that, although it has no insecticidal activity of its own, enhances certain insecticides such as Carbamates, Pyrethrins, Pyrethroids and Potency of Rotenone.
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- HY-W002421
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Biochemical Assay Reagents
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Others
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tert-butyl N-[(3R)-pyrrolidin-3-yl]carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-110178
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MAGL
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Inflammation/Immunology
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WWL123, a carbamate-based compound, is a potent and selective ABHD6 inhibitor. WWL123 can be used for research of inflammation, metabolic disorders (obesity and type II diabetes mellitus) and epilepsy .
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- HY-B0835
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Apoptosis
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Cardiovascular Disease
Neurological Disease
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Fenobucarb is a carbamate insecticide. Fenobucarb induces zebrafish developmental neurotoxicity through pathways involved in inflammation, oxidative stress, degeneration and apoptosis. Fenobucarb is a possible risk factor to cardiovascular and cerebrovascular systems in animals .
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- HY-W014240S1
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Isotope-Labeled Compounds
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Others
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Chlorpropham-d7 is the deuterium labeled Chlorpropham[1]. Chlorpropham is a carbamate herbicide and plant growth regulator. Chlorpropham inhibits mitosis and cell division by interfering with the organisation of the spindle microtubules[2][3].
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- HY-113416AS
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Isotope-Labeled Compounds
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Others
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Dehydroepiandrosterone sulfate-d6 (sodium dihydrate) is the deuterium labeled tert-Butyl N-[(1S)-1-[Methoxy(methyl)carbamoyl]-2-phenylethyl]carbamate[1].
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- HY-W321016S
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- HY-B1198S
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ENT-14250-d9
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Isotope-Labeled Compounds
Parasite
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Infection
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Piperonyl butoxide-d9 is the deuterium labeled Piperonyl butoxide. Piperonyl butoxide is a semisynthetic derivative of safrole,used as a component of pesticide formulations. It is a synergist, despite having no pesticidal activity of its own, it enhances the potency of certain pesticides such as Carbamates, Pyrethrins, Pyrethroids, and Rotenone.
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- HY-103522
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GABA Receptor
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Neurological Disease
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AA29504 is a ethyl carbamate with γ-aminobutyric acid (GABAA(HY-L120) receptor activity. AA29504 inhibits the delivery of the neurotransmitter gamma-aminobutyric acid in the central nervous system. AA29504 can be used to research anxiety, insomnia and other neuropsychiatric diseases .
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- HY-I1111S2
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- HY-79513
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tert-Butyl [(R)-1-(methoxycarbonyl)-2-hydroxyethyl]carbamate
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Amino Acid Derivatives
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Others
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(R)-Methyl 2-(tert-butoxycarbonylamino)-3-hydroxypropanoate is a serine derivative .
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- HY-P2831
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CESs
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Endogenous Metabolite
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Metabolic Disease
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Esterase, pig liver (CESs), namely carboxylate hydrolases, are widely distributed in nature, commonly found in mammalian liver, and often used in biochemical research. Esterase catalyzes the hydrolysis of a variety of endogenous and exogenous substrates, including esters, thioesters, carbamates, and amides, hydrolyzing carboxylic acid esters to the corresponding alcohols and carboxylic acids .
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- HY-W728451
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FAAH
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Cardiovascular Disease
Neurological Disease
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URB694 is a carbamate FAAH inhibitor that irreversibly carbamoylate the nucleophile catalytic serine in FAAH active site. URB694 exhibits antidepressant-like activity and cardioprotective effects. URB694 can be used to prepare 11C-Carbonyl-URB694 for in vivo positron emission tomography (PET) imaging studies of the brain FAAH .
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- HY-P1726A
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Melanocortin Receptor
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MSG606 TFA is a potent human MC1 receptor antagonist (IC50=17 nM). MSG606 TFA also partial agonist at human MC3 and MC5 receptors (EC50 values are 59 and 1300 nM, respectively). MSG606 TFA exhibits binding affinity for A375 melanoma cells in vitro. MSG606 TFA reverses the induced hyperalgesia in female mice, with no effect in male mice.
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- HY-P1726
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- HY-128035
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Phospholipase
MAGL
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ML-211 is a carbamate-based dual inhibitor of acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) (IC50=17 nM) and LYPLA2 (IC50=30 nM). ML-211 also inhibits theserine hydrolase ABHD11 with an IC50 value of 10 nM but is ≥ 50-fold selective for LYPLA in a panel of 20 additional serine hydrolases .
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- HY-144689
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Cholinesterase (ChE)
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Neurological Disease
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BChE-IN-3 (compound 45a) is a potent, selective, time-dependent and pseudoirreversible BChE inhibitor, with an IC50 of 56.9 nM. BChE-IN-3 also shows marginal and reversible (not time-dependent) inhibition of AChE .
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- HY-146431
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Angiotensin Receptor
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Others
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AT1R antagonist 1 (compound 10) is a potent AT1R selective ligand. AT1R antagonist 1 exhibits a fair AT1R affinity, with a Ki of 8.5 nM .
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- HY-146436
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Angiotensin Receptor
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Others
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AT1R antagonist 2 (compound 6) is a potent AT1R selective ligand. AT1R antagonist 2 exhibits a fair AT1R affinity, with a Ki of 26 nM .
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- HY-P0041A
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- HY-146314
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Monoamine Oxidase
Amyloid-β
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Neurological Disease
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MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects . MAO-B-IN-9 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-146313
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Cholinesterase (ChE)
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Neurological Disease
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BChE-IN-7 (compound 13) is a potent, selective, BBB-penetrated and reversible AChE and BChE inhibitor, with an IC50 of 0.06 μM (BChE). BChE-IN-7 can protect neuronal-like cells from toxic Aβ-species .
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- HY-146427
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Fungal
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Infection
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Antifungal agent 29 (compound 9d) is a potent, selective and non-toxic antifungal agent. Antifungal agent 29 shows antifungal activity towards Cryptococcus neoformans (MIC ≤ 0.23 μM) .
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Cat. No. |
Product Name |
Type |
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- HY-117695
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AQC
2 Publications Verification
6-Aminoquinolyl-N-hydroxysccinimidyl carbamate
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Fluorescent Dyes/Probes
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AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels .
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- HY-D1258
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VDP-green
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Fluorescent Dyes/Probes
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AC-green (VDP-green) is a β-allyl carbamate fluorescent probe for specifically imaging vicinal dithiol proteins (VDPs) in living systems (λex/λem=400/475 nm). AC-green can detect the reduced bovine serum albumin (rBSA) with high sensitivity. AC-green displays low toxicity and features high sensitivity, and is suitable for sensing VDPs in living cells and zebrafishes .
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Cat. No. |
Product Name |
Type |
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- HY-40172
-
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Biochemical Assay Reagents
|
tert-Butyl (3-aminopropyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-149037A
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N4-Spermine cholesteryl carbamate pentahydrochloride
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Drug Delivery
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GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
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- HY-30120
-
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Biochemical Assay Reagents
|
tert-Butyl N-[(1S,2S)-2-aminocyclohexyl]carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W127396
-
|
Biochemical Assay Reagents
|
Cholesteryl N-(trimethylammonioethyl)carbamate chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
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- HY-149037
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N4-Spermine cholesteryl carbamate
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Drug Delivery
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GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
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- HY-40174A
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Biochemical Assay Reagents
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tert-Butyl (2-aminoethyl)(methyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
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- HY-W002421
-
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Biochemical Assay Reagents
|
tert-butyl N-[(3R)-pyrrolidin-3-yl]carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-79513
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tert-Butyl [(R)-1-(methoxycarbonyl)-2-hydroxyethyl]carbamate
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Amino Acid Derivatives
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Others
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(R)-Methyl 2-(tert-butoxycarbonylamino)-3-hydroxypropanoate is a serine derivative .
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- HY-P0041A
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- HY-P10014
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- HY-P1726A
-
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Melanocortin Receptor
|
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MSG606 TFA is a potent human MC1 receptor antagonist (IC50=17 nM). MSG606 TFA also partial agonist at human MC3 and MC5 receptors (EC50 values are 59 and 1300 nM, respectively). MSG606 TFA exhibits binding affinity for A375 melanoma cells in vitro. MSG606 TFA reverses the induced hyperalgesia in female mice, with no effect in male mice.
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-Y1401S
-
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Methyl carbamate-d3 is the deuterium labeled Methyl carbamate[1].
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- HY-151877S
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Ethyl N-n-Butyl-d9-carbamate is the deuterium labeled Ethyl N-n-Butyl-carbamate[1].
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- HY-W016730S
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tert-Butyl (1-hydroxypropan-2-yl)carbamate-d6 is the deuterium labeled tert-Butyl (1-hydroxypropan-2-yl)carbamate[1].
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- HY-B0830S
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Isoprocarb-d3 is deuterium labeled Isoprocarb. Isoprocarb is carbamate insecticide that widely used to control rice paddy lice and leafhopper. Isoprocarb is also an AChE inhibitor[1].
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- HY-B0835S
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Fenobucarb-d3 is the deuterium labeled Fenobucarb. Fenobucarb is a carbamate insecticide. Fenobucarb induces zebrafish developmental neurotoxicity through pathways involved in inflammation, oxidative stress, degeneration and apoptosis[1].
|
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- HY-B1207S
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Urethane-d5 is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro[1].
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- HY-W059342S
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Etoxazole-d5 is the deuterium labeled Phenmedipham. Phenmedipham is a carbamate herbicide[1].
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- HY-121267S1
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Dicamba-d3 is the deuterium labeled Methyl (3,4-dichlorophenyl)carbamate[1].
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- HY-W014240S1
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Chlorpropham-d7 is the deuterium labeled Chlorpropham[1]. Chlorpropham is a carbamate herbicide and plant growth regulator. Chlorpropham inhibits mitosis and cell division by interfering with the organisation of the spindle microtubules[2][3].
|
-
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- HY-113416AS
-
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Dehydroepiandrosterone sulfate-d6 (sodium dihydrate) is the deuterium labeled tert-Butyl N-[(1S)-1-[Methoxy(methyl)carbamoyl]-2-phenylethyl]carbamate[1].
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- HY-W321016S
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SWEP-d3 is the deuterium labeled Fmoc-Tyr(tBu)-OH[1].
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- HY-B1198S
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Piperonyl butoxide-d9 is the deuterium labeled Piperonyl butoxide. Piperonyl butoxide is a semisynthetic derivative of safrole,used as a component of pesticide formulations. It is a synergist, despite having no pesticidal activity of its own, it enhances the potency of certain pesticides such as Carbamates, Pyrethrins, Pyrethroids, and Rotenone.
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- HY-I1111S2
-
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Fmoc-L-Val-OH- 13C5, 15N is a 15N-labeled and 13C-labled Pirimicarb. Pirimicarb is a fast-acting selective carbamate insecticide on a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables. Pirimicarb is an AChE inhibitor and an
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Cat. No. |
Product Name |
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Classification |
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- HY-W171071
-
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Alkynes
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Phenylethynylcarbinol carbamate is a agent used for neurology disease . Phenylethynylcarbinol carbamate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-146314
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Alkynes
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MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects . MAO-B-IN-9 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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