Search Result
Results for "
carboxylated
" in MedChemExpress (MCE) Product Catalog:
22
Biochemical Assay Reagents
11
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-131256A
-
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Histamine Receptor
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Inflammation/Immunology
Endocrinology
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Cetirizine Impurity C dihydrochloride is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist [1] [2] .
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-
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- HY-W005963
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Others
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Inflammation/Immunology
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Methyl 5-hydroxypyridine-2-carboxylate is a phenolic acid that can found in the stems of Mahonia fortune. Methyl 5-hydroxypyridine-2-carboxylate exhibits NO inhibitory effects in vitro .
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- HY-W454728S
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-
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- HY-131256
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Histamine Receptor
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Inflammation/Immunology
Endocrinology
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Cetirizine Impurity C is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist [1] [2] .
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- HY-149676
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Glucosidase
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Metabolic Disease
|
α-Glucosidase-IN-42 (Compound 26) is a 9-O-berberrubine carboxylate derivative. α-Glucosidase-IN-42 has potent α-glucosidase inhibitory activities with an IC50 value in the range of 1.61 μM. α-Glucosidase-IN-42 can be used for the research of antidiabetic .
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- HY-W454945S
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N-Boc-piperazine-d8
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Isotope-Labeled Compounds
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Others
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tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d8 is the deuterium labeled tert-Butyl piperazine-1-carboxylate[1].
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- HY-33615
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ADC Linker
PROTAC Linkers
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Cancer
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Methyl azetidine-3-carboxylate hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl azetidine-3-carboxylate hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs<
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- HY-W454729S
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4-Hydroxypiperidine-3,3,4,5,5-d5-N-t-BOC
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Isotope-Labeled Compounds
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Others
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tert-Butyl 4-hydroxypiperidine-1-carboxylate-3,3,4,5,5-d5 is the deuterium labeled tert-Butyl 4-hydroxypiperidine-1-carboxylate[1].
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- HY-W052600
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ADC Linker
PROTAC Linkers
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Cancer
|
Ethyl azetidine-3-carboxylate hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Ethyl azetidine-3-carboxylate hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]
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- HY-79635
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Bacterial
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Infection
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Methyl indole-3-carboxylate is a natural product isolated from Sorangium cellulosum strain Soce895. Methyl indole-3-carboxylate shows a weak activity against the Gram-positive Nocardia sp with a MIC value of 33.33 μg/mL .
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- HY-32208S
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Isotope-Labeled Compounds
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Others
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tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate-d4 is the deuterium labeled tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate[1].
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- HY-40151
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ADC Linker
PROTAC Linkers
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Cancer
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Methyl 1-Boc-azetidine-3-carboxylate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl 1-Boc-azetidine-3-carboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs [1
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- HY-138354A
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- HY-W019226
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ADC Linker
PROTAC Linkers
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Cancer
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Methyl 1-Cbz-azetidine-3-carboxylate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl 1-Cbz-azetidine-3-carboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1
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- HY-P5147
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nAChR
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Neurological Disease
|
α-Conotoxin GID is a paralytic peptide neurotoxin and a selective antagonist of nAChR, with IC50s of 5 nM (α7), 3 nM (α3β2), 150 nM (α4β2), respectively. α-Conotoxin GID is small disulfide-rich peptide, with potential to inhibit chronic pain. α-Conotoxin GID contains a C-terminal carboxylate, thus substitution with a C-terminal carboxamide results in loss of α4β2 nAChR. α-Conotoxin GID can be isolated from the Conus species .
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- HY-138354
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PROTAC Linkers
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Cancer
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Pyrroline-5-carboxylate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-N3288
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Others
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Others
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Methylcarbazole-3-carboxylate is a carbazole alkaloid can be isolated from the peel of Clausena lansium (Lour.) Skeels .
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- HY-W098127S
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Isotope-Labeled Compounds
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Others
|
Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate-d2 is the deuterium labeled Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate[1].
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- HY-78337
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Biochemical Assay Reagents
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Others
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Methyl pyrimidine-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W002603
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Biochemical Assay Reagents
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Others
|
Benzyl piperazine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
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- HY-69111
-
|
Biochemical Assay Reagents
|
Others
|
Ethyl oxazole-4-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
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- HY-W012071
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Biochemical Assay Reagents
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Others
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(S)-Benzyl pyrrolidine-2-carboxylate hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-50301
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Biochemical Assay Reagents
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Others
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Ethyl 2-aminothiazole-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W003995
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Biochemical Assay Reagents
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Others
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Ethyl 2-chloropyrimidine-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W002874
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Biochemical Assay Reagents
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Others
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Methyl 3-aminopyridine-4-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W002625
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Biochemical Assay Reagents
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Others
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Ethyl 2-bromothiazole-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-40146
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N-Boc-3-azetidinone
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Biochemical Assay Reagents
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Others
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tert-Butyl 3-oxoazetidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W003140
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Biochemical Assay Reagents
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Others
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tert-Butyl 3-hydroxypyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W012802
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Biochemical Assay Reagents
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Others
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Methyl 1H-pyrrole-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W008201
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Biochemical Assay Reagents
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Others
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tert-Butyl 3-formylpyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
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- HY-W016739
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Biochemical Assay Reagents
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Others
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Methyl 1H-indole-6-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W003321
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Biochemical Assay Reagents
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Others
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(S)-tert-Butyl 5-oxopyrrolidine-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-76366
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Biochemical Assay Reagents
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Others
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(S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-42448
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- HY-W002386
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Biochemical Assay Reagents
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Others
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Ethyl 2-amino-4-methylthiazole-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-34027
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Ethyl 5-methyl-1H-pyrazole-3-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W002128
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Biochemical Assay Reagents
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Others
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Ethyl 5-bromo-1H-indole-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
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- HY-W007997
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3-Amino-4-ethoxycarbonylpyrazole
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Biochemical Assay Reagents
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Others
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Ethyl 3-amino-1H-pyrazole-4-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-76558
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Biochemical Assay Reagents
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Others
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Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
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- HY-W007685
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Biochemical Assay Reagents
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Others
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Methyl 1H-1,2,4-triazole-3-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
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- HY-W002351
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Biochemical Assay Reagents
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Others
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Ethyl 1,5-dimethyl-1H-pyrazole-3-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W087433
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-
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- HY-W140616
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Others
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Others
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Ethyl 4'-hydroxy-[1,1'-biphenyl]-4-carboxylate is a 4-O-sulfamoyl-4-biphenyl based compound and can be used for synthesis of other compounds .
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- HY-149929
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Beta-lactamase
Bacterial
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Infection
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EBL-3183, an indole-2-carboxylate, is a potent metallo-β-lactamase (MBL) inhibitor. EBL-3183 is reversibly binding, non-covalent, competitive NDM-1 inhibitor with a pIC50 of 7.7 .
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- HY-W140284S
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Isotope-Labeled Compounds
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Others
|
6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate-d8 (hydrochloride) is the deuterium labeled 6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate hydrochloride[1].
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- HY-Y0949
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Methyl furan-2-carboxylate
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|
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Methyl 2-furoate (Methyl furan-2-carboxylate) is a building block in chemical synthesis. A flavoring agent in food. Found in cranberries, guava fruits, raisins and other fruits. Also present in baked potato, roasted filberts, roasted peanut, tomatoes, coffee, cocoa, okra, etc.
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- HY-N10590
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Deacetylalpinoside
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Others
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Others
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Arborescosidic acid (Deacetylalpinoside) is a carboxylated iridoid glucoside, that can be isolated from Veronica beccabunga (brooklime) .
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- HY-15992
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VEGFR
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Cancer
|
BIBF 1202 is the carboxylate metabolite of BIBF 1120 which inhibits VEGFR2 kinase with an IC50 of 62 nM.
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- HY-N7135
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Tyrosinase
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Others
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Tropolone is a Tropone derivative with a hydroxyl group at the 2-position, and is the precursor of many Azulene derivatives, such as 2-methylazulene-1-carboxylate. Tropolone is a potent mushroom tyrosinase inhibitor with an IC50 of 0.4 μM. Its inhibitory effect can be achieved by dialysis or excess CU 2+ Reversal .
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- HY-W009757
-
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Others
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Others
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Ethyl 5-hydroxy-2-methyl-1H-indole-3-carboxylate is an active compound, and can be used in the synthesis of 2-phenylthiomethyl-indole derivatives, 2-phenylthiomethyl-indole derivative is a 5-lipoxygenase (5-LO) inhibitor .
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- HY-152372
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Nucleoside Antimetabolite/Analog
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Others
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Methyl 6-amino-9-β-D-ribofuranosyl-9H-purine-2-carboxylate is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-32291
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(S)-Methyl 5-oxopyrrolidine-2-carboxylate; L-Pyroglutamic acid methyl ester
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Others
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Others
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Methyl L-pyroglutamate ((S)-Methyl 5-oxopyrrolidine-2-carboxylate;L-Pyroglutamic acid methyl ester) is isolated from P. oleracea and has anti-inflammatory activity .
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- HY-131579
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Drug Metabolite
|
Inflammation/Immunology
|
Deschloro Cetirizine Dihydrochloride is a Cetirizine impurity. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist.
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- HY-15992S
-
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Isotope-Labeled Compounds
VEGFR
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Cancer
|
BIBF 1202- 13C,d3 is the 13C- and deuterium labeled BIBF 1202. BIBF 1202 is the carboxylate metabolite of BIBF 1120 which inhibits VEGFR2 kinase with an IC50 of 62 nM.
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- HY-12966
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- HY-101884A
-
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Others
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Neurological Disease
|
Biotinylated-D-lysine TFA is a conjugate of L-biotin and D-lysine, where the carboxylate of L-biotin is coupled with the ϵ-amine of D-lysine via a secondary amide bond. Biotinylated-D-lysine TFA is an isomer of the neuroanatomical tracer Biocyte.
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- HY-17042
-
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Histamine Receptor
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Inflammation/Immunology
Endocrinology
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Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response .
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-
- HY-17042A
-
P071
|
Histamine Receptor
|
Inflammation/Immunology
Endocrinology
|
Cetirizine dihydrochloride, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine dihydrochloride marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response .
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- HY-P2831
-
CESs
|
Endogenous Metabolite
|
Metabolic Disease
|
Esterase, pig liver (CESs), namely carboxylate hydrolases, are widely distributed in nature, commonly found in mammalian liver, and often used in biochemical research. Esterase catalyzes the hydrolysis of a variety of endogenous and exogenous substrates, including esters, thioesters, carbamates, and amides, hydrolyzing carboxylic acid esters to the corresponding alcohols and carboxylic acids .
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- HY-D1643
-
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Biochemical Assay Reagents
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Others
|
5,5'-Dinitro BAPTA AM is a membrane-permeant, high-affinity calcium chelator, it can be used for investigation of the role of cytosolic Ca 2+. 5,5'-Dinitro BAPTA AM can be loaded by incubation into live cells, and is cleaved by cytosolic esterases to liberate the active tetra-carboxylate ligand .
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- HY-17042AS
-
|
Isotope-Labeled Compounds
Histamine Receptor
|
Inflammation/Immunology
|
Cetirizine-d4 (dihydrochloride) is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
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- HY-17042AS1
-
|
Isotope-Labeled Compounds
Histamine Receptor
|
Inflammation/Immunology
|
Cetirizine-d8 (dihydrochloride) is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
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- HY-101884
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(+)-Biocytin
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Endogenous Metabolite
|
Neurological Disease
|
Biocytin is a conjugate of D-biotin and L-lysine, where the carboxylate of D-biotin is coupled with the ϵ-amine of L-lysine via a secondary amide bond. Biocytin is a classical neuroanatomical tracer commonly used to map brain connectivity. Biocytin is used as a versatile marker in anterograde, retrograde and intracellular neuroanatomical investigations and in biotinidase assays .
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- HY-17042S
-
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Histamine Receptor
|
Inflammation/Immunology
|
Cetirizine-d4 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
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- HY-17042S1
-
|
Histamine Receptor
|
Inflammation/Immunology
|
Cetirizine-d8 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
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- HY-132994
-
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Others
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Others
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TVD-0003510 is a carboxamide derivative, and involves in synthesis of (2-((6-(2-aminopyrimidine-5-carboxamido)-8-methoxy-3,4-dihydro-2H-pyrimido[1,2-c]quinazolin-9-yl)oxy)ethyl)piperazine-l-carboxylate (C51), as a part of tert-butyl2-(4-hydroxyphenyl)acetate .
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- HY-107767
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DC 81
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Antibiotic
Apoptosis
DNA/RNA Synthesis
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Cancer
|
Antibiotic DC 81 (DC 81), an antitumor antibiotic produced by Streptomyces species, is a PBD (pyrrolo[2,1-c][1,4]benzodiazepine). Antibiotic DC 81 is potent inhibitor of nucleic acid synthesis. Antibiotic DC 81 can recognize and bind to specific sequences of DNA and form a labile covalent adduct .
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- HY-W250143
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Biochemical Assay Reagents
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Others
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Toluidine blue (ZnCl2) is a basic thiazine dye commonly used as a biological stain for microscopy. It has a deep bluish-purple color and is commonly used to stain nucleic acids such as DNA and RNA, as well as to stain mast cells, cartilage, and other connective tissues. Toluidine blue (ZnCl2) stains the acidic components of these tissues, such as sulfated or carboxylated mucopolysaccharides. It is frequently used in histology, cytology, and pathology applications to aid in the diagnosis of various diseases and conditions. The dye is usually applied to tissue sections prior to microscopic examination and can be differentiated using an acidic alcohol solution. Toluidine blue (ZnCl2) is a relatively simple and inexpensive stain with good reproducibility, making it a popular choice for many laboratories.
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Cat. No. |
Product Name |
Type |
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- HY-W250143
-
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Dyes
|
Toluidine blue (ZnCl2) is a basic thiazine dye commonly used as a biological stain for microscopy. It has a deep bluish-purple color and is commonly used to stain nucleic acids such as DNA and RNA, as well as to stain mast cells, cartilage, and other connective tissues. Toluidine blue (ZnCl2) stains the acidic components of these tissues, such as sulfated or carboxylated mucopolysaccharides. It is frequently used in histology, cytology, and pathology applications to aid in the diagnosis of various diseases and conditions. The dye is usually applied to tissue sections prior to microscopic examination and can be differentiated using an acidic alcohol solution. Toluidine blue (ZnCl2) is a relatively simple and inexpensive stain with good reproducibility, making it a popular choice for many laboratories.
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Cat. No. |
Product Name |
Type |
-
- HY-78337
-
|
Biochemical Assay Reagents
|
Methyl pyrimidine-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-W002603
-
|
Biochemical Assay Reagents
|
Benzyl piperazine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-69111
-
|
Biochemical Assay Reagents
|
Ethyl oxazole-4-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-W012071
-
|
Biochemical Assay Reagents
|
(S)-Benzyl pyrrolidine-2-carboxylate hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-34497
-
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Biochemical Assay Reagents
|
Ethyl 3-trifluoromethylpyrazole-4-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-50301
-
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Biochemical Assay Reagents
|
Ethyl 2-aminothiazole-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-W003995
-
|
Biochemical Assay Reagents
|
Ethyl 2-chloropyrimidine-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-W002874
-
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Biochemical Assay Reagents
|
Methyl 3-aminopyridine-4-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W002625
-
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Biochemical Assay Reagents
|
Ethyl 2-bromothiazole-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-40146
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N-Boc-3-azetidinone
|
Biochemical Assay Reagents
|
tert-Butyl 3-oxoazetidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W003140
-
|
Biochemical Assay Reagents
|
tert-Butyl 3-hydroxypyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W012802
-
|
Biochemical Assay Reagents
|
Methyl 1H-pyrrole-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008201
-
|
Biochemical Assay Reagents
|
tert-Butyl 3-formylpyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-W016739
-
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Biochemical Assay Reagents
|
Methyl 1H-indole-6-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W003321
-
|
Biochemical Assay Reagents
|
(S)-tert-Butyl 5-oxopyrrolidine-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-76366
-
|
Biochemical Assay Reagents
|
(S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002386
-
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Biochemical Assay Reagents
|
Ethyl 2-amino-4-methylthiazole-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002128
-
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Biochemical Assay Reagents
|
Ethyl 5-bromo-1H-indole-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W007997
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3-Amino-4-ethoxycarbonylpyrazole
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Biochemical Assay Reagents
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Ethyl 3-amino-1H-pyrazole-4-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-76558
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Biochemical Assay Reagents
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Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W007685
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Biochemical Assay Reagents
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Methyl 1H-1,2,4-triazole-3-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W002351
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Biochemical Assay Reagents
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Ethyl 1,5-dimethyl-1H-pyrazole-3-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-42448
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- HY-P5147
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nAChR
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Neurological Disease
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α-Conotoxin GID is a paralytic peptide neurotoxin and a selective antagonist of nAChR, with IC50s of 5 nM (α7), 3 nM (α3β2), 150 nM (α4β2), respectively. α-Conotoxin GID is small disulfide-rich peptide, with potential to inhibit chronic pain. α-Conotoxin GID contains a C-terminal carboxylate, thus substitution with a C-terminal carboxamide results in loss of α4β2 nAChR. α-Conotoxin GID can be isolated from the Conus species .
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- HY-P4557
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Peptides
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Others
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H-Phe-Leu-Glu-Glu-Leu-OH is a synthetic pentapeptide, which can be used as the substrate of vitamin K dependent carboxylase, and a glutamyl residue in the generated product is carboxylated .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-W454728S
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tert-Butyl 4-oxopiperidine-1-carboxylate-3,3,5,5-d4 is the deuterium labeled tert-Butyl 4-oxopiperidine-1-carboxylate[1].
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- HY-W454945S
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tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d8 is the deuterium labeled tert-Butyl piperazine-1-carboxylate[1].
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- HY-W454729S
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tert-Butyl 4-hydroxypiperidine-1-carboxylate-3,3,4,5,5-d5 is the deuterium labeled tert-Butyl 4-hydroxypiperidine-1-carboxylate[1].
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- HY-32208S
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tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate-d4 is the deuterium labeled tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate[1].
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- HY-W098127S
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Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate-d2 is the deuterium labeled Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate[1].
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- HY-W140284S
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6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate-d8 (hydrochloride) is the deuterium labeled 6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate hydrochloride[1].
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- HY-15992S
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BIBF 1202- 13C,d3 is the 13C- and deuterium labeled BIBF 1202. BIBF 1202 is the carboxylate metabolite of BIBF 1120 which inhibits VEGFR2 kinase with an IC50 of 62 nM.
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- HY-17042AS
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Cetirizine-d4 (dihydrochloride) is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
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- HY-17042AS1
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Cetirizine-d8 (dihydrochloride) is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
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- HY-17042S
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Cetirizine-d4 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
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- HY-17042S1
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Cetirizine-d8 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
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Cat. No. |
Product Name |
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Classification |
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- HY-126271
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Alkynes
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PYCR1-IN-1 (compound 4) is a pyrroline-5-carboxylate reductase 1 (PYCR1) inhibitor with an IC50 of 8.8 µM. PYCR1-IN-1 has anticancer effects .
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