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cell+morphology

" in MedChemExpress (MCE) Product Catalog:

23

Inhibitors & Agonists

1

Fluorescent Dye

4

Biochemical Assay Reagents

2

Peptides

4

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Products

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W088068
    Wright's stain

    		Fluorescent Dye Others
    Wright's stain is a composite cell stain that mainly binds to intracellular nucleic acids, proteins and other components through thiazine dyes (such as methylene blue) and eosin. Wright's stain is pH-dependent (optimal pH 6.4-6.7) and achieves cell morphology resolution by differentially staining the cytoplasm and nucleus. Under alkaline conditions, thiazine dyes bind to nucleic acids to form purple, and acidic eosin binds to cytoplasmic proteins to form red, which can form contrasting cell morphological features. Wright's stain can clearly display the fine structures of blood cells and bone marrow cells (such as nuclear chromatin and granules) and quickly evaluate cell morphological abnormalities .
    Wright's stain
  • HY-118773
    MreB Perturbing Compound A22 hydrochloride

    A22 hydrochloride

    		 Bacterial Infection
    MreB Perturbing Compound A22 hydrochloride (A22 hydrochloride) is a reversible MreB inhibitor and antimicrobial agent that exhibits bacteriostatic activity against Escherichia coli, with low activity against Gram-positive bacteria. MreB Perturbing Compound A22 hydrochloride rapidly and reversally delocalizes MreB from the helical/circular structures in cells, impairs MreB function, and reduces the binding of MreB to the chromosomal region proximal to the replication origin. MreB Perturbing Compound A22 hydrochloride alters the cell morphology of caulobacters to round/lemon-shaped, slows caulobacter growth, blocks their cell division, and induces the formation of spherical morphology, asymmetric division, and anucleate cells in Escherichia coli. MreB Perturbing Compound A22 hydrochloride is used for studies related to bacterial rod-shaped morphology determination, chromosome segregation, and cell division mechanisms .
    MreB Perturbing Compound A22 hydrochloride
  • HY-19820A
    NSC45586 sodium
    1 Publications Verification

    		 Akt Ser/Thr Protease Apoptosis MMP Cardiovascular Disease Neurological Disease Inflammation/Immunology
    NSC45586 sodium is an inhibitor of PHLPP. NSC45586 sodium targets the PP2C phosphatase domains of PHLPP1 and PHLPP2, blocks the phosphatase activity of PHLPP, increases the expression level of FOXO1 in the nucleus, and reduces the protein expression of PHLPP1. NSC45586 sodium activates the AKT survival signaling pathway, enhances IGF-1-induced AKT activation, and inhibits the phosphorylation of AKT/ERK under basal conditions. NSC45586 sodium reduces staurosporine-induced neuronal death, preserves notochord cell morphology and KRT19 expression, inhibits cell apoptosis (apoptosis), improves the viability and proliferation of nucleus pulposus cells, upregulates the expression of ACAN/SOX9, and downregulates the expression of MMP13. NSC45586 sodium binds tightly to bovine serum albumin (bovine serum albumin), and exerts a more significant effect on nucleus pulposus in male individuals. NSC45586 sodium can be used in studies related to global cerebral ischemia and intervertebral disc degeneration .
    NSC45586 sodium
  • HY-N2438
    Methylophiopogonanone B
    2 Publications Verification

    		 Ras Microtubule/Tubulin Cancer
    Methylophiopogonanone B is a homoisoflavonoid compound. Methylophiopogonanone B can be isolated from O. japonicus root. Methylophiopogonanone B promotes Rho activation and Tubulin depolymerization. Methylophiopogonanone B significantly increases GTP-Rho, but not GTP-Rac or GTP-CDC42. Methylophiopogonanone B induces cell morphological change via melanocyte dendrite retraction and stress fiber formation. Methylophiopogonanone B exhibits strong antioxidant activity. Methylophiopogonanone B can be used in the research of cervical cancer .
    Methylophiopogonanone B
  • HY-158976
    Sodium lactate ringer's solution

    Lactated ringer's solution (LRS)

    		 Biochemical Assay Reagents Collagen HSP Inflammation/Immunology
    Sodium lactate ringer's solution (Lactated ringer's solution (LRS)) is an isotonic crystal intravenous injection and arthroscopic irrigation solution containing racemic sodium lactate and electrolytes such as sodium, potassium, calcium and chloride (130 mEq sodium/L, 274 mOsm/L), which can be used as a cell integrity protectant. Sodium lactate ringer's solution maintains the integrity of human meniscus cells, ensures that they retain normal cell morphology, membrane regularity, size and density, and does not alter the mRNA expression levels of α1 (I) procollagen, α1 (II) procollagen, aggrecan or HSP70. Sodium lactate ringer's solution can be applied to studies related to extracellular fluid deficiency and meniscus tears .
    Sodium lactate ringer's solution
  • HY-NP163A
    Wheat germ agglutinin-AF488

    WGA-AF488

    		 Fluorescent Dye Cancer
    Wheat germ agglutinin-AF488 (WGA-AF488) is a cell membrane-specific staining agent prepared by conjugating wheat germ agglutinin with the Alexa Fluor 488 (HY-D1304) fluorescent dye, and it binds to cell surface glycoproteins with high affinity. Wheat germ agglutinin-AF488 is applied in fluorescence microscopy and confocal imaging techniques, and it can clearly label the membrane structures of various cells including breast cancer cells, enabling high-resolution visual observation. Wheat germ agglutinin-AF488 is used in studies of breast cancer and triple-negative breast cancer to observe cell morphology and membrane dynamic changes .
    Wheat germ agglutinin-AF488
  • HY-13563
    Batabulin

    T138067

    		 Microtubule/Tubulin Apoptosis Cancer
    Batabulin (T138067) is an antitumor agent, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization. Batabulin affects cell morphology and leads to cell-cycle arrest ultimately induces apoptotic cell death .
    Batabulin
  • HY-N6701
    Dihydrocytochalasin B

    		Arp2/3 Complex DNA/RNA Synthesis Calcium Channel Inflammation/Immunology
    Dihydrocytochalasin B is an Actin disruptor. Dihydrocytochalasin B disrupts actin microfilament bundles, inhibits actin polymerization, and alters intracellular actin cytoskeletal structures. Dihydrocytochalasin B blocks the initiation of DNA synthesis. Dihydrocytochalasin B inhibits Calcium transport. Dihydrocytochalasin B inhibits cytokinesis and alters cell morphology. Dihydrocytochalasin B can be used in studies related to rickets .
    Dihydrocytochalasin B
  • HY-13563A
    Batabulin sodium

    T138067 sodium

    		 Microtubule/Tubulin Apoptosis Cancer
    Batabulin sodium (T138067 sodium) is an antitumor agent, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization. Batabulin sodium affects cell morphology and leads to cell-cycle arrest ultimately induces apoptotic cell death .
    Batabulin sodium
  • HY-Y0317I
    Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP

    Disodium sulfate, meets analytical specification of Ph. Eur. BP USP

    		 Biochemical Assay Reagents Cancer
    Sodium sulfate anhydrous (Disodium sulfate), meets analytical specification of Ph. Eur. BP USP is an orally active multifunctional ionic salt that serves as a protein precipitant, collagen fibril bundling inducer, and chlorine-free sodium source. Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP promotes collagen fibril bundling to increase matrix pore size, alters cancer cell morphology and regulates their migration direction via geometric signals, and separates plasma/serum proteins or concentrates proteins at 37°C without causing thermal denaturation. In poultry farming applications, Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP improves laying performance and eggshell quality, and is safe and effective at an addition level of 0.3-1.5%, while a high concentration of 3.0% causes negative physiological effects. Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP can be widely applied in scientific research on cervical cancer and related fields .
    Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP
  • HY-178943
    Neuroprotective agent 15

    		Cholinesterase (ChE) Cannabinoid Receptor Aldehyde Dehydrogenase (ALDH) Caspase Apoptosis Neurological Disease
    Neuroprotective agent 15 (Compound 3e) is a neuroprotective agent. Neuroprotective agent 15 is a selective butyrylcholinesterase (BChE) inhibitor, with IC50 values of 2.6 and 114.3 μM for BChE and AChE respectively. Neuroprotective agent 15 has cannabinoid CB2 receptor (CB2 receptor) agonistic activity. Neuroprotective agent 15 can reduce cell death, LDH release and Caspase-3/7 activity, and inhibit apoptosis. Neuroprotective agent 15 can reduce the formation of superoxide free radicals, maintain cell morphology, and significantly lower oxidative stress levels. Neuroprotective agent 15 can be used in the research of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease .
    Neuroprotective agent 15
  • HY-N14658
    Phosmidosine B

    		Others Cancer
    Phosmidosine B can inhibit the cell cycle progression and cell morphology recovery of srcts-NRK cells .
    Phosmidosine B
  • HY-N15110
    Phosmidosine

    		Fungal Infection
    Phosmidosine can inhibit the cell cycle progression and cell morphology recovery of srcts-NRK cells. Phosmidosine A has antifungal effects .
    Phosmidosine
  • HY-P11021
    ToAP2

    		Fungal Antibiotic Infection
    ToAP2 is a potent antimicrobial peptide. ToAP2 affects C. albicans membrane permeability and produces changes in fungal cell morphology .
    ToAP2
  • HY-P11021A
    ToAP2 TFA

    		Fungal Antibiotic Infection
    ToAP2 TFA is a potent antimicrobial peptide. ToAP2 TFA affects C. albicans membrane permeability and produces changes in fungal cell morphology .
    ToAP2 TFA
  • HY-145438
    Antitumor agent-38

    		Others Cancer
    Antitumor agent-38 is a potent antitumor agents. Antitumor agent-38 shows antiproliferative activity for cancer cells. Antitumor agent-38 induces cell cycle arrest at the late S and G2/M phase without interfering with microtubule formation or cell morphology[1].
    Antitumor agent-38
  • HY-155249
    KGP591

    		Microtubule/Tubulin Cancer
    KGP591 is a tubulin polymerization inhibitor (IC50 0.57 µM). KGP591 induces significant G2/M stagnation, inhibits cell migration, disrupts microtubule structure and cell morphology in MDA-MB-231 cells. KGP591 shows antitumor activity in orthotopic model of kidney cancer (RENCA) .
    KGP591
  • HY-173052
    SLW131

    		CXCR Inflammation/Immunology
    SLW131 (Compound 10) is the antagonist for CCR7 with a good affinity of Ki of 9.85 nM. SLW131 inhibits CCL19-induced Go protein activation with an IC50 of 29.4 μM, inhibits β-arrestin2 recruitment with an IC50 of 6.0 μM. SLW131 inhibits CCL19-induced cell morphological changes in primary BMDCs, and CCR7-mediated migration in mouse CD4+ T cell .
    SLW131
  • HY-157699
    1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium

    		Liposome Biochemical Assay Reagents
    1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium is a membrane-bound signaling molecule with intracellular activity in regulating membrane trafficking and signal transduction. 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium can be used in the preparation of liposomes to enhance the efficiency of compound delivery. 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium can also act as a coordinator of the actin cytoskeleton and participate in the regulation of cell morphology and motility.
    1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium
  • HY-157706
    PI(3,4)P2 (18:1) ammonium salt

    		PI3K Cardiovascular Disease Metabolic Disease Cancer
    PI(3,4)P2 (18:1) ammonium salt is a phosphatidylinositol 3 kinase (PI3K) activator. PI(3,4)P2 (18:1) ammonium salt is a polyphosphorylated phosphatidylinositol that promotes the activation of AKT (protein kinase B) by activating PI3K, which affects cell metabolism, growth and survival. PI(3,4)P2 (18:1) ammonium salt is also involved in regulating dynamic changes in the cytoskeleton, affecting cell morphology and movement. PI(3,4)P2 (18:1) ammonium salt can be used in research on the development of cancer, diabetes and cardiovascular disease .
    PI(3,4)P2 (18:1) ammonium salt
  • HY-118773R
    MreB Perturbing Compound A22 hydrochloride (Standard)

    A22 hydrochloride (Standard)

    		 Reference Standards Bacterial Infection
    MreB Perturbing Compound A22 hydrochloride (Standard) is the analytical standard for MreB Perturbing Compound A22 hydrochloride (HY-118773). This product is intended for research and analytical applications. MreB Perturbing Compound A22 hydrochloride (A22 hydrochloride) is a reversible MreB inhibitor and antimicrobial agent that exhibits bacteriostatic activity against Escherichia coli, with low activity against Gram-positive bacteria. MreB Perturbing Compound A22 hydrochloride rapidly and reversally delocalizes MreB from the helical/circular structures in cells, impairs MreB function, and reduces the binding of MreB to the chromosomal region proximal to the replication origin. MreB Perturbing Compound A22 hydrochloride alters the cell morphology of caulobacters to round/lemon-shaped, slows caulobacter growth, blocks their cell division, and induces the formation of spherical morphology, asymmetric division, and anucleate cells in Escherichia coli. MreB Perturbing Compound A22 hydrochloride is used for studies related to bacterial rod-shaped morphology determination, chromosome segregation, and cell division mechanisms .
    MreB Perturbing Compound A22 hydrochloride (Standard)
  • HY-117740
    Heronamide C

    		Others Others
    Heronamide C is a polyketide macrolactam isolated from marine Streptomyces that has the activity of producing reversible non-cytotoxic effects on mammalian cell morphology.
    Heronamide C
  • HY-W720329
    Indaziflam

    		Herbicide DNA/RNA Synthesis Others
    Indaziflam is an alkyltriazine herbicide. Indaziflam targets the cellulose synthase complex and inhibits cellulose biosynthesis in plant cell walls. Indaziflam induces radial swelling of plants, ectopic lignification, inhibition of root and hypocotyl elongation, abnormal root and cell morphology, and also induces DNA strand breaks and micronucleus formation in HepG2 cells. Indaziflam can be used for research on monocot weed control .
    Indaziflam

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