chemotactic

By Targets:	Antibiotic (1) Biochemical Assay Reagents (1) Calcium Channel (2) Caspase (1) CCR (1) DOCK (1) Endogenous Metabolite (1) Formyl Peptide Receptor (FPR) (2) TNF Receptor (1)
By Research Areas:	Cancer (5) Endocrinology (1) Inflammation/Immunology (8) Neurological Disease (4)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P4998

Chemotactic Domain of Elastin	Biochemical Assay Reagents	Cancer
Chemotactic Domain of Elastin is an elastin-derived peptide with chemotactic effects on certain tumor cells, such as M27 tumor cells. Chemotactic Domain of Elastin can be used in cancer research .

HY-103348

Boc-Asp(OMe)-fluoromethyl ketone Boc-Asp(OMe)-FMK	Caspase	Inflammation/Immunology
Boc-Asp(OME)-Fluoromethyl Ketone is a broad range caspase inhibitor that inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8 .

HY-P2311

Defensin HNP-2 human

Endogenous Metabolite Antibiotic

Defensin HNP-2 human is an endogenous antibiotic peptide and monocyte chemotactic peptide produced by human neutrophils.

Defensin HNP-2 human	Endogenous Metabolite Antibiotic
Defensin HNP-2 human is an endogenous antibiotic peptide and monocyte chemotactic peptide produced by human neutrophils.

HY-P1117

MMK1	Formyl Peptide Receptor (FPR) Calcium Channel	Neurological Disease Inflammation/Immunology
MMK1 is a potent and selective human formyl peptide receptor like-1 (FPRL-1/FPR2) agonist with EC₅₀s of <2 nM and >10000 nM for FPRL-1 and FPR1, respectively. MMK1 is a potent chemotactic and calcium-mobilizing agonist. MMK1 potently activates phagocytic leukocytes and enhances Pertussis Toxin (HY-112779)-sensitive production by human monocytes of proinflammatory cytokines IL-1b and IL-6. MMK1 exerts anxiolytic-like activity .

HY-P1117A

MMK1 TFA	Formyl Peptide Receptor (FPR) Calcium Channel	Neurological Disease Inflammation/Immunology
MMK1 TFA is a potent and selective human formyl peptide receptor like-1 (FPRL-1/FPR2) agonist with EC₅₀s of <2 nM and >10000 nM for FPRL-1 and FPR1, respectively. MMK1 TFA is a potent chemotactic and calcium-mobilizing agonist. MMK1 TFA potently activates phagocytic leukocytes and enhances Pertussis Toxin (HY-112779)-sensitive production by human monocytes of proinflammatory cytokines IL-1b and IL-6. MMK1 TFA exerts anxiolytic-like activity .

HY-P0224

N-Formyl-Met-Leu-Phe 5+ Cited Publications fMLP; N-Formyl-MLF	TNF Receptor	Inflammation/Immunology
N-Formyl-Met-Leu-Phe (fMLP; N-Formyl-MLF) is a chemotactic peptide and a specific ligand of N-formyl peptide receptor (FPR). N-Formyl-Met-Leu-Ph is reported to inhibit TNF-alpha secretion.

HY-149921

Antiangiogenic agent 3	Others	Cancer
Antiangiogenic agent 3 (compound 3) is a potent antiangiogenic agent. Antiangiogenic agent 3 is an inhibitor of human umbilical vein endothelial cells (HUVEC). Antiangiogenic agent 3 inhibits HUVEC migration and chemotactic motilities. Antiangiogenic agent 3 also decreases the gene expression of Src, cdc42, and MAPK .

HY-B0498

Bindarit 10+ Cited Publications AF2838	CCR	Neurological Disease Inflammation/Immunology Endocrinology Cancer
Bindarit (AF2838) is a selective inhibitor of the monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7, and MCP-2/CCL8, and no effect on other CC and CXC chemokines such as MIP-1α/CCL3, MIP-1β/CCL4, MIP-3/CCL23. Bindarit also has anti-inflammatory activity .

HY-153128

DOCK2-IN-1	DOCK	Inflammation/Immunology
DOCK2-IN-1 (compound 3), a CPYPP (HY-110100) analogue, is an inhibitor of DOCK2 as well (IC₅₀=19.1 μM). DOCK2-IN-1 binds to DOCK2 DHR-2 domain in a reversible manner to inhibits its catalytic activity. DOCK2-IN-1 blocks the activation of both chemokine receptor- and antigen receptor-mediated Rac in lymphocytes. DOCK2-IN-1 significantly suppresses chemotactic response and T cell activation .

Cat. No.	Product Name

HY-L132

Chemokine Compound Library	146 compounds
Chemokines, or chemotactic cytokines, are small cytokines or signaling proteins secreted by cells. They are a component of intercellular communication, controlling the directional movement of immune cells especially leukocytes, as well as other cell types, for instance, endothelial and epithelial cells, which are essential to maintain human health and the function of the immune system. The biological effects of chemokines are achieved by binding to chemokine receptors, which are G protein-coupled receptors found on the surface of leukocytes. Some chemokine receptors are involved in directing tumor metastasis and over-expression by certain tumors. So inhibiting the interaction between chemokine and chemokine receptors on the surface of tumor cells may be a new possible therapeutic approach. Some chemokine receptors are coreceptors for HIV entry, and related inhibitors have been approved by the FDA to treat patients with HIV. Obviously, chemokines and chemokine receptors have become new targets for studying cancer, HIV, inflammation, and other diseases. MCE supplies a unique collection of 146 chemokine or chemokine receptor inhibitors and activators, all of which have the identified inhibitory or activated effect on chemokine or chemokine receptors. MCE Chemokine Library is a useful tool for drug research related to cancer, AIDS, and wound therapy.

Chemokine Compound Library

146 compounds

Chemokines, or chemotactic cytokines, are small cytokines or signaling proteins secreted by cells. They are a component of intercellular communication, controlling the directional movement of immune cells especially leukocytes, as well as other cell types, for instance, endothelial and epithelial cells, which are essential to maintain human health and the function of the immune system.

The biological effects of chemokines are achieved by binding to chemokine receptors, which are G protein-coupled receptors found on the surface of leukocytes. Some chemokine receptors are involved in directing tumor metastasis and over-expression by certain tumors. So inhibiting the interaction between chemokine and chemokine receptors on the surface of tumor cells may be a new possible therapeutic approach. Some chemokine receptors are coreceptors for HIV entry, and related inhibitors have been approved by the FDA to treat patients with HIV. Obviously, chemokines and chemokine receptors have become new targets for studying cancer, HIV, inflammation, and other diseases.

MCE supplies a unique collection of 146 chemokine or chemokine receptor inhibitors and activators, all of which have the identified inhibitory or activated effect on chemokine or chemokine receptors. MCE Chemokine Library is a useful tool for drug research related to cancer, AIDS, and wound therapy.

Cat. No.	Product Name	Target	Research Area

HY-P4998

Chemotactic Domain of Elastin	Biochemical Assay Reagents	Cancer
Chemotactic Domain of Elastin is an elastin-derived peptide with chemotactic effects on certain tumor cells, such as M27 tumor cells. Chemotactic Domain of Elastin can be used in cancer research .

HY-P2642

Peptide 78	Peptides	Inflammation/Immunology
Peptide 78, a chemotactic cytokine, a 78 amino acid protein member of the IL-8 or C-X-C chemokine supergene family. ENA-78 plays an important role in the elicitation of predominantly neutrophils (PMNs) into the joints of rheumatoid arthritis (RA) .

HY-P2311

Defensin HNP-2 human

Endogenous Metabolite Antibiotic

Defensin HNP-2 human is an endogenous antibiotic peptide and monocyte chemotactic peptide produced by human neutrophils.

Defensin HNP-2 human	Endogenous Metabolite Antibiotic
Defensin HNP-2 human is an endogenous antibiotic peptide and monocyte chemotactic peptide produced by human neutrophils.

HY-P1117

MMK1	Formyl Peptide Receptor (FPR) Calcium Channel	Neurological Disease Inflammation/Immunology
MMK1 is a potent and selective human formyl peptide receptor like-1 (FPRL-1/FPR2) agonist with EC₅₀s of <2 nM and >10000 nM for FPRL-1 and FPR1, respectively. MMK1 is a potent chemotactic and calcium-mobilizing agonist. MMK1 potently activates phagocytic leukocytes and enhances Pertussis Toxin (HY-112779)-sensitive production by human monocytes of proinflammatory cytokines IL-1b and IL-6. MMK1 exerts anxiolytic-like activity .

HY-P1117A

MMK1 TFA	Formyl Peptide Receptor (FPR) Calcium Channel	Neurological Disease Inflammation/Immunology
MMK1 TFA is a potent and selective human formyl peptide receptor like-1 (FPRL-1/FPR2) agonist with EC₅₀s of <2 nM and >10000 nM for FPRL-1 and FPR1, respectively. MMK1 TFA is a potent chemotactic and calcium-mobilizing agonist. MMK1 TFA potently activates phagocytic leukocytes and enhances Pertussis Toxin (HY-112779)-sensitive production by human monocytes of proinflammatory cytokines IL-1b and IL-6. MMK1 TFA exerts anxiolytic-like activity .

HY-P2588

Osteocalcin (1-49) (human)	Peptides	Inflammation/Immunology Cancer
Osteocalcin (1-49) (human) is a vitamin K-dependent bone specific protein. Osteocalcin (1-49) (human) is chemotactic for several of the cell types frequently found at bone remodeling surfaces .

HY-P0224

N-Formyl-Met-Leu-Phe 5+ Cited Publications fMLP; N-Formyl-MLF	TNF Receptor	Inflammation/Immunology
N-Formyl-Met-Leu-Phe (fMLP; N-Formyl-MLF) is a chemotactic peptide and a specific ligand of N-formyl peptide receptor (FPR). N-Formyl-Met-Leu-Ph is reported to inhibit TNF-alpha secretion.

HY-P1764

Secretoneurin, rat	Peptides	Neurological Disease
Secretoneurin, rat, a 33-amino acid polypeptide, is generated by proteolytic processing of secretogranin II (SgII). Secretoneurin, rat induces dopamine release in the rat striatum in vivo and in vitro, and it exerts a very strong chemotactic effect on monocytes and eosinophils but not on granulocytes .

HY-P3735

Bone Gla Protein (45-49)	Peptides	Cancer
Bone Gla Protein (45-49) is the 45-49 fragment of gamma-carboxyglutamic acid (GLA)-containing protein from bone (BGP, osteocalcin), which has chemotactic activity in vitro for a number of cells which are found adjacent to endosteal bone surfaces in vivo .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0498

Bindarit 10+ Cited Publications AF2838	Structural Classification Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Umbelliferae Disease Research Fields Endocrinology Echinacea angustifolia DC. Cancer	CCR
Bindarit (AF2838) is a selective inhibitor of the monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7, and MCP-2/CCL8, and no effect on other CC and CXC chemokines such as MIP-1α/CCL3, MIP-1β/CCL4, MIP-3/CCL23. Bindarit also has anti-inflammatory activity .

Species:	Human (9) Porcine (1) Rat (2) Mouse (5) Pig (1)
Tag:	His (10) Tag Free (8)
Source:	HEK293 (5) E. coli Cell-free (1) E. coli (12)

Cat. No.	Compare	Product Name	Species	Source

HY-P71275

	S100A8 Protein, Rat (His) 2 Publications Verification Protein S100-A8; S100a8; Calgranulin-A; chemotactic cytokine CP-10; Leukocyte L1 complex light chain; Migration inhibitory factor-related protein 8; MRP-8; Pro-inflammatory S100 cytokine; S100 calcium-binding protein A8; Caga; Mrp8	Rat	E. coli
	S100A8 protein functions as a danger signal in inflammation, activating innate immune cells by binding to receptors like Toll-like receptor 4 (TLR4) and receptor for advanced glycation endproducts (AGER). This triggers signaling pathways that enhance the pro-inflammatory response. S100A8 Protein, Rat (His) is the recombinant rat-derived S100A8 protein, expressed by E. coli , with C-6*His labeled tag. The total length of S100A8 Protein, Rat (His) is 89 a.a., with molecular weight of ~13.0 kDa.

HY-P700164AF

	Animal-Free MCP-1/CCL2 Protein, Mouse (His) Monocyte chemotactic Protein-1; MCP-1; JE	Mouse	E. coli
	MCP-1/CCL2 protein serves as a CCR2 ligand, inducing a potent chemotactic response and intracellular calcium mobilization in monocytes and basophils, with no impact on neutrophils or eosinophils. Crucial in neuropathic pain and enhancing NMDA-mediated synaptic transmission in dopamine D1 and D2 receptor-containing neurons, it may involve MAPK/ERK-dependent GRIN2B/NMDAR2B phosphorylation. In monomer or homodimer equilibrium, it binds to endothelial cells via glycosaminoglycan side chains and interacts with TNFAIP6 through its Link domain. Animal-Free MCP-1/CCL2 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeMCP-1/CCL2 protein, expressed by E. coli, with N-His labeled tag. The total length of Animal-Free MCP-1/CCL2 Protein, Mouse (His) is 125 a.a., with molecular weight of ~14.65 kDa.

HY-P700133AF

	Animal-Free IL-8/CXCL8 Protein, Human (His) Interleukin-8; IL-8; C-X-C Motif Chemokine 8; Emoctakin; Granulocyte chemotactic Protein 1; GCP-1; Monocyte-Derived NeutrophIL chemotactic Factor; MDNCF; Monocyte-Derived NeutrophIL-Activating Peptide; MONAP; NeutrophIL-Activating Protein 1; NAP-1; Protein 3-10C; T-Cell chemotactic Factor; IL8; CXCL8	Human	E. coli
	IL-8/CXCL8 protein, a vital chemotactic factor, orchestrates inflammatory responses by attracting neutrophils, basophils, and T-cells to clear pathogens. It activates neutrophils and binds to CXCR1/CXCR2 receptors, initiating downstream signaling pathways. IL-8/CXCL8 homodimerizes, disrupted by tick evasin-3, and interacts with TNFAIP6, potentially regulating chemokine activity in the inflammatory microenvironment. Animal-Free IL-8/CXCL8 Protein, Human (His) is the recombinant human-derived animal-FreeIL-8/CXCL8 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-8/CXCL8 Protein, Human (His) is 72 a.a., with molecular weight of ~9.32 kDa.

HY-P7159

	Eotaxin/CCL11 Protein, Human rHuEotaxin/CCL11; C-C motif chemokine 11; Eosinophil chemotactic protein; SCYA11	Human	E. coli
	Eotaxin/CCL11 Protein, Human is a potent chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia.

HY-P70432

	IL-8/CXCL8 Protein, Human Interleukin-8; IL-8; C-X-C Motif Chemokine 8; Emoctakin; Granulocyte chemotactic Protein 1; GCP-1; Monocyte-Derived Neutrophil chemotactic Factor; MDNCF; Monocyte-Derived Neutrophil-Activating Peptide; MONAP; Neutrophil-Activating Protein 1; NAP-1; Protein 3-10C; T-Cell chemotactic Factor; IL8; CXCL8	Human	E. coli
	IL-8/CXCL8 protein, a vital chemotactic factor, orchestrates inflammatory responses by attracting neutrophils, basophils, and T-cells to clear pathogens. It activates neutrophils and binds to CXCR1/CXCR2 receptors, initiating downstream signaling pathways. IL-8/CXCL8 homodimerizes, disrupted by tick evasin-3, and interacts with TNFAIP6, potentially regulating chemokine activity in the inflammatory microenvironment. IL-8/CXCL8 Protein, Human is the recombinant human-derived IL-8/CXCL8 protein, expressed by E. coli , with tag free. The total length of IL-8/CXCL8 Protein, Human is 77 a.a., with molecular weight of ~11.0 kDa.

HY-P7160

	Eotaxin/CCL11 Protein, Mouse rMuEotaxin/CCL11; C-C motif chemokine 11; Eosinophil chemotactic protein; SCYA11	Mouse	E. coli
	Eotaxin/CCL11 Protein, Mouse is a potent chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia.

HY-P70569

	IL-8/CXCL8 Protein, Human (HEK293, His) Interleukin-8; IL-8; C-X-C Motif Chemokine 8; CXCL8; Emoctakin; Granulocyte chemotactic Protein 1; GCP-1; Monocyte-Derived Neutrophil chemotactic Factor; MDNCF; Monocyte-Derived Neutrophil-Activating Peptide; MONAP; Neutrophil-Activating Protein 1; NAP-1	Human	HEK293
	Interleukin-8 (IL-8), also known as CXCL8 or NAP-1, is a pro-inflammatory CXC chemokine. IL-8 acts on human neutrophils via two receptors, CXCR1 and CXCR2. IL-8 has a conserved Glu-Leu-Arg (ELR) N-terminal motif, and is an agonist for CXCR1/CXCR2. IL-8 is produced by various cells including leukocytes, endothelial cells, and epithelial cells. IL-8/CXCL8 Protein, Human (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags. It consists of 79 amino acids (E21-S99).

HY-P700250AF

	Animal-Free IL-8/CXCL8 Protein, Pig (His) Interleukin-8; IL-8; C-X-C Motif Chemokine 8; CXCL8; Emoctakin; Granulocyte chemotactic Protein 1; GCP-1; Monocyte-Derived NeutrophIL chemotactic Factor; MDNCF; Monocyte-Derived NeutrophIL-Activating Peptide; MONAP; NeutrophIL-Activating Protein 1; NAP-1	Pig	E. coli
	IL-8/CXCL8 protein, a vital chemotactic factor, orchestrates inflammatory responses by attracting neutrophils, basophils, and T-cells to clear pathogens. It activates neutrophils and binds to CXCR1/CXCR2 receptors, initiating downstream signaling pathways. IL-8/CXCL8 homodimerizes, disrupted by tick evasin-3, and interacts with TNFAIP6, potentially regulating chemokine activity in the inflammatory microenvironment. Animal-Free IL-8/CXCL8 Protein, Pig (His) is the recombinant pig-derived animal-FreeIL-8/CXCL8 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-8/CXCL8 Protein, Pig (His) is 78 a.a., with molecular weight of ~10.04 kDa.

HY-P71901

	CCL11 Protein, Rat Ccl11; Scya11Eotaxin; C-C motif chemokine 11; Eosinophil chemotactic protein; Small-inducible cytokine A11	Rat	E. coli
	CCL11 protein directly promotes eosinophil accumulation in allergic reactions, selectively affecting eosinophils without influencing other immune cells. It binds to CCR3, emphasizing its role in eosinophil-mediated processes. The interaction between CCL11 and its receptor provides insights into the regulation of allergic reactions. CCL11 Protein, Rat is the recombinant rat-derived CCL11 protein, expressed by E. coli , with tag free. The total length of CCL11 Protein, Rat is 74 a.a., with molecular weight of ~10 kDa.

HY-P7760

	CCL24/Eotaxin-2 Protein, Mouse 1 Publications Verification rMuCCL24; C-C motif chemokine 24; Eosinophil chemotactic protein 2; Eotaxin-2; Small-inducible cytokine A24; Scya24; Ccl24;	Mouse	E. coli
	CCL24/Eotaxin-2 Protein, Mouse is a CC chemokine that interacts with the chemokine receptor CCR3 to induce eosinophil chemotaxis and mediate atopic diseases, parasitic infections and systemic diseases, as well as promote cellular transport and regulate inflammatory and fibrotic activities. CCL24/Eotaxin-2 Protein, Mouse is a recombinant mouse CCL24/Eotaxin-2 (V27-V119) protein expressed by E. coli.

HY-P7764

	MCP-1/CCL2 Protein, Mouse 4 Publications Verification rMuCCL2; C-C motif chemokine 2; Monocyte chemoattractant protein 1; Monocyte chemotactic protein 1; MCP-1; Ccl2; Scya2	Mouse	E. coli
	MCP-1/CCL2 Protein, Mouse is a cytokine belonging to the CC chemokine family that interacts with the CCR2 chemokine receptor on the cell surface to mediate inflammatory immune responses, viral infections, and tumorigenesis. MCP-1/CCL2 Protein, Mouse is a mouse MCP-1/CCL2 (Q24-R96) expressed by E.coil.

HY-P702227

	C5AR2 Protein, Human (Cell-Free, His) C5a anaphylatoxin chemotactic receptor 2; Complement component 5a receptor 2; G-protein coupled receptor 77	Human	E. coli Cell-free
	The C5AR2 protein is a receptor for C3a, C4a, and C5a peptides as well as ASP/C3adesArg, C4adesArg, and C5adesArg, and is weakly coupled to G(i)-mediated signaling pathways. It interacts with C3 and exhibits higher affinity for the lipogenic hormone ASP. C5AR2 Protein, Human (Cell-Free, His) is the recombinant human-derived C5AR2 protein, expressed by E. coli Cell-free , with C-10*His labeled tag. The total length of C5AR2 Protein, Human (Cell-Free, His) is 337 a.a., with molecular weight of 38.9 kDa.

HY-P79178

	IL-8/CXCL8 Protein, Porcine Interleukin-8; CXCL8; IL-8; Alveolar macrophage chemotactic factor I; AMCF-I; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; IL8; Interleukin 8	Porcine	E. coli
	IL-8/CXCL8 protein, a vital chemotactic factor, orchestrates inflammatory responses by attracting neutrophils, basophils, and T-cells to clear pathogens. It activates neutrophils and binds to CXCR1/CXCR2 receptors, initiating downstream signaling pathways. IL-8/CXCL8 homodimerizes, disrupted by tick evasin-3, and interacts with TNFAIP6, potentially regulating chemokine activity in the inflammatory microenvironment. IL-8/CXCL8 Protein, Porcine is the recombinant Porcine-derived IL-8/CXCL8 protein, expressed by E. coli , with tag free. The total length of IL-8/CXCL8 Protein, Porcine is 79 a.a., with molecular weight of ~12.97 kDa.

HY-P7766

	CCL24/Eotaxin-2 Protein, Human (HEK293, His) rHuCCL24, His; C-C motif chemokine 24 ; CCL24; Eosinophil chemotactic protein; Eotaxin-2; Myeloid progenitor inhibitory factor 2; Small-inducible cytokine A24; Ckb-6; MPIF-2; SCYA24	Human	HEK293
	CCL24/Eotaxin-2 Protein, Human (HEK293, His) is a CC chemokine that interacts with the chemokine receptor CCR3 to induce eosinophil chemotaxis and mediate atopic diseases, parasitic infections and systemic diseases, as well as promote cellular transport and regulate inflammatory and fibrotic activities. CCL24/Eotaxin-2 Protein, Human (HEK293, His) is a recombinant human CCL24/Eotaxin-2 (V27-C119) protein expressed by HEK293 with a his tag.

HY-P7771

	MCP-2/CCL8 Protein, Mouse (HEK293, His) rMuCCL8, His; C-C motif chemokine 8; Ccl8; Monocyte chemoattractant protein 2; Monocyte chemotactic protein 2; MCP-2; Small-inducible cytokine A8; Mcp2; Scya8	Mouse	HEK293
	MCP-2/CCL8 Protein, Mouse (HEK293, His) is a CC chemokine that interacts with CCR1, CCR2B, CCR3, and CCR5 to mediate host inflammatory immune responses, tumorigenesis, and antiviral infections. MCP-2/CCL8 Protein, Mouse (HEK293, His ) is a recombinant mouse MCP-2/CCL8 (E20-P97) protein expressed by HEK293 with a his tag.

HY-P70450

	RANTES/CCL5 Protein, Human 2 Publications Verification C-C Motif Chemokine 5; EoCP; Eosinophil chemotactic Cytokine; SIS-Delta; Small-Inducible Cytokine A5; T Cell-Specific Protein P228; TCP228; T-Cell-Specific Protein RANTES; CCL5; D17S136E; SCYA5	Human	E. coli
	CCL5 Protein, Human is a key pro-inflammatory chemokine in the CC chemokine family that interacts with CCR1, CCR3, CCR4, and CCR5 to mediate inflammatory immune responses, viral infections, and tumorigenesis.CCL5 Protein, Human is a recombinant human CCL5(S24-S91) protein expressed by E. coli.

HY-P7770

	MCP-2/CCL8 Protein, Human (HEK293, His) rHuCCL8, His; C-C Motif Chemokine 8; HC14; Monocyte Chemoattractant Protein 2; Monocyte chemotactic Protein 2; MCP-2; Small-Inducible Cytokine A8; CCL8; MCP2; SCYA10; SCYA8	Human	HEK293
	MCP-2/CCL8 Protein, Human (HEK293, His) is a CC chemokine that interacts with CCR1, CCR2B, CCR3, and CCR5 to mediate host inflammatory immune responses, tumorigenesis, and antiviral infections. MCP-2/CCL8 Protein, Human (HEK293, His ) is a recombinant human MCP-2/CCL8 (Q24-P99) protein expressed by HEK293 with a his tag.

HY-P700398

	C5AR1 Protein-VLP, Human (HEK293, His) complement component 5a receptor 1; C5R1, complement component 5 receptor 1 (C5a ligand); C5a anaphylatoxin chemotactic receptor; C5A; C5AR; CD88; C5a-R; C5a ligand; C5a anaphylatoxin receptor; complement component 5 receptor 1; C5R1	Human	HEK293
	C5AR1 Protein-VLP, Human (HEK293, His) is recommended for animal immunization, ELISA. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays.


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Cat. No.	Product Name	Application	Reactivity

HY-P81171

MCP1 Antibody MCP-1/CCL2; C-C motif chemokine 2; CCL 2; CCL2; CCL2_HUMAN; Chemokine (C C motif) ligand 2; Chemokine C C motif ligand 2; Chemokine CC Motif Ligand 2; GDCF 2; GDCF 2 HC11; GDCF-2; GDCF2; HC11; HSMCR30; HSMCR30; JE; MCAF; MCP 1; MCP-1; MGC9434; Monocyte chemoattractant protein 1; Monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; Monocyte secretory protein JE; SCYA2; Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je); Small inducible cytokine A2; Small inducible cytokine subfamily A (Cys Cys), member 2; Small inducible cytokine subfamily A Cys Cys member 2; Small-inducible cytokine A2; SMC CF; SMC-CF; SMCCF.	WB; ELISA; IHC-P; IHC-F; Flow-Cyt; IF	Human, Rat(predicted: Mouse, Dog, Pig, Horse, Rabbit)
MCP1 Antibody is an unconjugated, approximately 11 kDa, rabbit-derived, anti-MCP1 polyclonal antibody. MCP1 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, rat, and predicted: mouse, dog, pig, horse, rabbit background without labeling.

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