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Results for "

cofactor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aldehyde Dehydrogenase (ALDH) (1) Apoptosis (10) Bacterial (5) Biochemical Assay Reagents (2) COX (4) DNA/RNA Synthesis (9) Drug Metabolite (1) Endogenous Metabolite (59) Fatty Acid Synthase (FASN) (3) Ferroptosis (5) Fluorescent Dye (13) HBV (6) HCV (2) HCV Protease (2) HIV (4) HIV Integrase (1) Interleukin Related (1) Isotope-Labeled Compounds (13) Liposome (2) Mitochondrial Metabolism (6) NF-κB (4) NO Synthase (2) Phospholipase (1) Protease Activated Receptor (PAR) (1) Reactive Oxygen Species (5) SARS-CoV (2) Thrombin (3) Thymidylate Synthase (1) Thyroid Hormone Receptor (1) TNF Receptor (1)
By Research Areas:	Cancer (28) Cardiovascular Disease (9) Infection (10) Inflammation/Immunology (22) Metabolic Disease (22) Neurological Disease (16)
Click Chemistry:	Alkynes (5)

109

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

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Natural
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Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113325

NADP 4 Publications Verification	Endogenous Metabolite	Others
NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .

HY-F0002

NADP sodium salt 4 Publications Verification Sodium NADP	Endogenous Metabolite	Others
NADP sodium salt is the sodium salt form of NADP (HY-113325). NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .

HY-F0002A

NADP disodium salt 4 Publications Verification Disodium NADP	Endogenous Metabolite	Others
NADP disodium salt is the disodium salt form of NADP (HY-113325). NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .

HY-125954B

Uridine diphosphate galuronic acid trisodium UDP-α-D-galuronic acid trisodium	Biochemical Assay Reagents	Metabolic Disease
Uridine diphosphate galuronic acid (UDP-α-D-galuronic acid) trisodium is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase .

HY-113325A

NADP sodium hydrate	Endogenous Metabolite	Others
NADP sodium hydrate, a β-Nicotinamide adenine dinucleotide phosphate sodium salt, is a redox cofactor. NADP sodium hydrate is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH) .

HY-14769

Folitixorin 1 Publications Verification 5,10-Methylenetetrafolate; ANX-510 free acid	Endogenous Metabolite	Cancer
Folitixorin (5,10-methylenetetrahydrofolate) is a cofactor and an analog of leucovorin. Folitixorin is a promising agent for modulation of 5-FU cytotoxicity in adjuvant cancer research .

HY-F0003

NADPH tetrasodium salt 5+ Cited Publications	Ferroptosis Endogenous Metabolite	Cancer
NADPH tetrasodium salt functions as an important *cofactor* in a variety of metabolic and biosynthetic pathways. NADPH tetrasodium salt plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication. The demand for NADPH tetrasodium salt is particularly high in proliferating cancer cells, where it acts as a cofactor for the synthesis of nucleotides, proteins, and fatty acids. NADPH tetrasodium salt is also essential for the neutralization of the dangerously high levels of reactive oxygen species (ROS) generated by increased metabolic activity. NADPH tetrasodium salt is an endogenous inhibitor of ferroptosis .

HY-141513

NH-3 1 Publications Verification	Thyroid Hormone Receptor	Neurological Disease
NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC₅₀ of 55 nM. NH-3, a derivative of the selective thyromi-metic GC-1, inhibits binding of thyroid hormones to their receptor and that inhibits cofactor recruitment . NH-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-123275A

H-D-Phe-Pip-Arg-pNA hydrochloride S-2238 hydrochloride	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform .

HY-123275

H-D-Phe-Pip-Arg-pNA S-2238	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform .

HY-123275C

H-D-Phe-Pip-Arg-pNA dihydrochloride S-2238 dihydrochloride	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform .

HY-123275B

H-D-Phe-Pip-Arg-pNA acetate S-2238 acetate	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform .

HY-128851

Coenzyme A	Fatty Acid Synthase (FASN) Endogenous Metabolite	Metabolic Disease
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-128851A

Coenzyme A trilithium	Endogenous Metabolite Fatty Acid Synthase (FASN)	Metabolic Disease
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-128851B

Coenzyme A sodium	Endogenous Metabolite Fatty Acid Synthase (FASN)	Metabolic Disease
Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-125954A

Uridine diphosphate glucuronic acid ammonium UDP-α-D-glucuronic acid ammonium	Endogenous Metabolite	Metabolic Disease
Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium is a *cofactor* that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid (ammonium) is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid (ammonium), as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum .

HY-107383

Tetrahydrobiopterin (Rac)-Sapropterin	NO Synthase Endogenous Metabolite	Inflammation/Immunology
Tetrahydrobiopterin ((Rac)-Sapropterin) is a *cofactor* of the aromatic amino acid hydroxylases enzymes and also acts as an essential *cofactor* for all nitric oxide synthase (NOS) isoforms.

HY-N0492

α-Lipoic Acid 5 Publications Verification Thioctic acid; (±)-α-Lipoic acid; DL-α-Lipoic acid	NF-κB HIV Mitochondrial Metabolism Endogenous Metabolite Apoptosis	Infection Inflammation/Immunology Cancer
α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .

HY-N0492A

α-Lipoic Acid sodium Thioctic acid sodium; (±)-α-Lipoic acid sodium; DL-α-Lipoic acid sodium	NF-κB HIV Mitochondrial Metabolism Endogenous Metabolite Apoptosis	Infection Inflammation/Immunology Cancer
α-Lipoic Acid (Thioctic acid) sodium is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid sodium inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid sodium induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid sodium can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .

HY-F0003A

NADPH tetracyclohexanamine

5+ Cited Publications

Ferroptosis Endogenous Metabolite Others

NADPH tetracyclohexanamine is a ubiquitous cofactor and biological reducing agent.
HY-102015

6-Biopterin

L-Biopterin
NO Synthase Endogenous Metabolite Neurological Disease Cancer

6-Biopterin (L-Biopterin), a pterin derivative, is a NO synthase cofactor.

NADPH tetracyclohexanamine 5+ Cited Publications	Ferroptosis Endogenous Metabolite	Others
NADPH tetracyclohexanamine is a ubiquitous cofactor and biological reducing agent.

6-Biopterin L-Biopterin	NO Synthase Endogenous Metabolite	Neurological Disease Cancer
6-Biopterin (L-Biopterin), a pterin derivative, is a NO synthase cofactor.

HY-14614A

S-Adenosyl-L-methionine chloride dihydrochloride S-Adenosyl methionine chloride dihydrochloride; Ademetionine chloride dihydrochloride; AdoMet chloride dihydrochloride	Others	Others
S-(5'-Adenosyl)-L-methionine chloride dihydrochloride is a methyl donor and cofactor.

HY-N0680

Thiamine hydrochloride Thiamine chloride hydrochloride; Vitamin B1 hydrochloride	Endogenous Metabolite Apoptosis HBV Bacterial	Neurological Disease
Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-N0111

Coenzyme Q10 1 Publications Verification CoQ10; Ubiquinone-10; Ubidecarenone	Endogenous Metabolite Reactive Oxygen Species Ferroptosis	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-145503

Decanoyl-L-carnitine chloride

Others Metabolic Disease

Decanoyl-L-carnitine chloride is an ester derivative of L-carnitine, which is an important cofactor of fatty acid metabolism .
HY-160653

JPL

Bacterial Infection

JPL is a InhA-cofactor-ligand 3FNG inhibitor, and can be used for study of tuberculosis .

Decanoyl-L-carnitine chloride	Others	Metabolic Disease
Decanoyl-L-carnitine chloride is an ester derivative of L-carnitine, which is an important cofactor of fatty acid metabolism .

JPL	Bacterial	Infection
JPL is a InhA-cofactor-ligand 3FNG inhibitor, and can be used for study of tuberculosis .

HY-P2969

*Complement factor* I**	Endogenous Metabolite	Metabolic Disease
Complement factor I is a serine protease that downregulates complement activity in the fluid phase and/or on cell surfaces in conjunction with one of its cofactors, factor H (FH), complement receptor 1 (CR1/CD35), C4 binding protein (C4BP) or membrane cofactor protein (MCP/CD46) .

HY-P3186

Glucose dehydrogenase, recombinant Microorganisms	Endogenous Metabolite	Metabolic Disease
Glucose dehydrogenase, recombinant Microorganisms is a oxidoreductase. Glucose dehydrogenase (GDH) catalyzes the oxidation of β-D-glucose to β-D-glucono-1,5-lactone with simultaneous reduction of the cofactor NADP ⁺ to NADPH or, to a lesser extent, NAD ⁺ to NADH. Glucose dehydrogenase (GDH) accepts both NAD ⁺ and NADP ⁺ as cofactors and can be used for the regeneration of NADH and NADPH .

HY-B1654

Flavin adenine dinucleotide FAD	Endogenous Metabolite	Cardiovascular Disease
Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

HY-B0511S2

Biotin-d2 Vitamin B7-d₂; Vitamin H-d₂; D-Biotin-d₂	Endogenous Metabolite	Metabolic Disease
Biotin-d₂ is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.

HY-N0680S1

Thiamine-d3 hydrochloride Thiamine chloride-d₃ hydrochloride; Vitamin B1-d₃ hydrochloride	Isotope-Labeled Compounds Endogenous Metabolite Apoptosis HBV	Neurological Disease
Thiamine-d₃ (hydrochloride) is the deuterium labeled Thiamine hydrochloride. Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-N0680S2

Thiamine-d4 hydrochloride Thiamine chloride-d₄ hydrochloride; Vitamin B1-d₄ hydrochloride	Endogenous Metabolite Apoptosis HBV	Neurological Disease
Thiamine-d₄ (hydrochloride) is deuterium labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-B1654A

Flavin adenine dinucleotide disodium salt FAD disodium salt; FAD-Na2	Endogenous Metabolite	Cardiovascular Disease
Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

HY-B0511S

Biotin-d2-1 Vitamin B7 d₂-1; Vitamin H d₂-1; D-Biotin d₂-1	Endogenous Metabolite	Metabolic Disease
Biotin-d₂-1 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.

HY-B0511S1

rel-Biotin-d4 rel-Vitamin B7-d₄; rel-Vitamin H-d₄; rel-D-Biotin-d₄	Endogenous Metabolite	Metabolic Disease
rel-Biotin-d₄ is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.

HY-N0680S

Thiamine monochloride-13C hydrochloride	Endogenous Metabolite Apoptosis HBV	Neurological Disease
Thiamine monochloride- ¹³C₄ (hydrochloride) is the deuterium labeled Thiamine hydrochloride. Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-18733

Lipoic acid 5+ Cited Publications (R)-(+)-α-Lipoic acid; R-(+)-Thioctic acid	Mitochondrial Metabolism Endogenous Metabolite Reactive Oxygen Species	Inflammation/Immunology Cancer
Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid.

HY-112790

Adenosylcobalamin Coenzyme B12; Cobamamide; AdoCbl	Endogenous Metabolite	Metabolic Disease
Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B₁₂ which is a cofactor for methylmalonyl CoA mutase

HY-W013046

Phosphoribosyl pyrophosphate pentasodium PRPP pentasodium	Endogenous Metabolite	Others
Phosphoribosyl pyrophosphate (PRPP) pentasodium is an important metabolite required in the biosynthesis of purine and pyrimidine nucleotides, the amino acids histidine and tryptophan, and the cofactors NAD and NADP .

HY-N0680S3

Thiamine-13C3 hydrochloride Thiamine chloride-¹³C₃ hydrochloride; Vitamin B1-¹³C₃ hydrochloride	Isotope-Labeled Compounds Endogenous Metabolite Apoptosis HBV	Neurological Disease
Thiamine- ¹³C₃ (hydrochloride) is the ¹³C-labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-139199

4-Hydroxyphenylbutazone	Drug Metabolite	Others
4-Hydroxyphenylbutazone is a metabolite of Phenylbutazone. Phenylbutazone, a nonsteroidal anti-inflammatory agent (NSAID), is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS) .

HY-W048449

L-Biotin	Others	Metabolic Disease
L-Biotin, also known as biotin, is a water-soluble vitamin that is an essential cofactor in the carboxylation of several enzymes. L-Biotin is involved in fatty acid synthesis and amino acid metabolism .

HY-N0680R

Thiamine hydrochloride (Standard) Thiamine chloride hydrochloride (Standard); Vitamin B1 hydrochloride (Standard)	Bacterial Endogenous Metabolite HBV Apoptosis	Neurological Disease
Thiamine (hydrochloride) (Standard) is the analytical standard of Thiamine (hydrochloride). This product is intended for research and analytical applications. Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes .

HY-W009439

Glucosamine 6-sulfate GlcN6P; D-Glucosamine-6-sulfate	Biochemical Assay Reagents	Others
Glucosamine 6-sulfate (GlcN6P) is an organic cofactor that splits phosphodiester bonds. Glucosamine 6-sulfate plays a variety of catalytic roles in glmS ribozymes .

HY-D1904

D-Luciferin 6'-methyl ether	Fluorescent Dye	Others
D-Luciferin 6'-methyl ether sodium salt is a firefly luciferase inhibitor. D-Luciferin 6'-methyl ether sodium salt is a cofactor in Luc-catalyzed synthesis of dinucleoside polyphosphates .

HY-N0111S2

Coenzyme Q10-d9 CoQ10-d₉; Ubiquinone-10-d₉	Isotope-Labeled Compounds Endogenous Metabolite Reactive Oxygen Species Ferroptosis	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Coenzyme Q10-d₉ is the deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-128606

Thiamine diphosphate analog 1	Others	Metabolic Disease
Thiamine diphosphate analog 1 is an analog of Thiamine diphosphate . Thiamine diphosphate is the active form of vitamin B₁. Thiamine diphosphate a universal cofactor involved in pivotal cellular pathways .

HY-113402

Gamma-glutamylcysteine γ-Glu-Cys	Endogenous Metabolite	Inflammation/Immunology
Gamma-glutamylcysteine (γ-Glutamylcysteine), a dipeptide containing cysteine and glutamic acid, is a precursor to glutathione (GSH). Gamma-glutamylcysteine is a cofactor for glutathione peroxidase (GPx) to increase GSH levels .

HY-N0111S

Coenzyme Q10-d6 CoQ10-d₆; Ubiquinone-10-d₆	Isotope-Labeled Compounds Endogenous Metabolite Reactive Oxygen Species Ferroptosis	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Coenzyme Q10-d₆ is deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-140656F

Biotin-PEG-Biotin (MW 20000)	Fluorescent Dye	Others
Biotin-PEG-Biotin (MW 20000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113325

NADP 4 Publications Verification	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .

HY-F0002A

NADP disodium salt 4 Publications Verification Disodium NADP	Structural Classification other families Microorganisms Classification of Application Fields Animals Ketones, Aldehydes, Acids Source classification Other Diseases Plants Disease Research Fields	Endogenous Metabolite
NADP disodium salt is the disodium salt form of NADP (HY-113325). NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .

HY-14769

Folitixorin 1 Publications Verification 5,10-Methylenetetrafolate; ANX-510 free acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
Folitixorin (5,10-methylenetetrahydrofolate) is a cofactor and an analog of leucovorin. Folitixorin is a promising agent for modulation of 5-FU cytotoxicity in adjuvant cancer research .

HY-128851

Coenzyme A	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Fatty Acid Synthase (FASN) Endogenous Metabolite
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-113325A

NADP sodium hydrate	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NADP sodium hydrate, a β-Nicotinamide adenine dinucleotide phosphate sodium salt, is a redox cofactor. NADP sodium hydrate is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH) .

HY-128851A

Coenzyme A trilithium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Fatty Acid Synthase (FASN)
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-128851B

Coenzyme A sodium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Fatty Acid Synthase (FASN)
Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-125954A

Uridine diphosphate glucuronic acid ammonium UDP-α-D-glucuronic acid ammonium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium is a *cofactor* that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid (ammonium) is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid (ammonium), as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum .

HY-107383

Tetrahydrobiopterin (Rac)-Sapropterin	Alkaloids Structural Classification Classification of Application Fields Other Alkaloids Source classification Disease markers Endogenous metabolite Inflammation/Immunology Disease Research Fields Cardiovascular System Disorder	NO Synthase Endogenous Metabolite
Tetrahydrobiopterin ((Rac)-Sapropterin) is a *cofactor* of the aromatic amino acid hydroxylases enzymes and also acts as an essential *cofactor* for all nitric oxide synthase (NOS) isoforms.

HY-N0492

α-Lipoic Acid 5 Publications Verification Thioctic acid; (±)-α-Lipoic acid; DL-α-Lipoic acid	Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	NF-κB HIV Mitochondrial Metabolism Endogenous Metabolite Apoptosis
α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .

HY-N0492A

α-Lipoic Acid sodium Thioctic acid sodium; (±)-α-Lipoic acid sodium; DL-α-Lipoic acid sodium	Infection Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Cancer	NF-κB HIV Mitochondrial Metabolism Endogenous Metabolite Apoptosis
α-Lipoic Acid (Thioctic acid) sodium is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid sodium inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid sodium induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid sodium can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .

HY-102015

6-Biopterin L-Biopterin	Natural Products Source classification Disease markers Nervous System Disorder Endogenous metabolite	NO Synthase Endogenous Metabolite
6-Biopterin (L-Biopterin), a pterin derivative, is a NO synthase cofactor.

HY-N0680

Thiamine hydrochloride Thiamine chloride hydrochloride; Vitamin B1 hydrochloride	Structural Classification Natural Products Human Gut Microbiota Metabolites Source classification Endogenous metabolite	Endogenous Metabolite Apoptosis HBV Bacterial
Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-N0111

Coenzyme Q10 1 Publications Verification CoQ10; Ubiquinone-10; Ubidecarenone	Structural Classification Neurological Disease Classification of Application Fields Anti-aging Source classification Metabolic Disease Endogenous metabolite Quinones Human Gut Microbiota Metabolites Microorganisms Benzene Quinones Inflammation/Immunology Disease Research Fields Cancer	Endogenous Metabolite Reactive Oxygen Species Ferroptosis
Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-B1654

Flavin adenine dinucleotide FAD	Cardiovascular Disease Natural Products Human Gut Microbiota Metabolites other families Microorganisms Classification of Application Fields Source classification Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

HY-B1654A

Flavin adenine dinucleotide disodium salt FAD disodium salt; FAD-Na2	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

HY-18733

Lipoic acid 5+ Cited Publications (R)-(+)-α-Lipoic acid; R-(+)-Thioctic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Mitochondrial Metabolism Endogenous Metabolite Reactive Oxygen Species
Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid.

HY-112790

Adenosylcobalamin Coenzyme B12; Cobamamide; AdoCbl	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B₁₂ which is a cofactor for methylmalonyl CoA mutase

HY-W013046

Phosphoribosyl pyrophosphate pentasodium PRPP pentasodium	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Phosphoribosyl pyrophosphate (PRPP) pentasodium is an important metabolite required in the biosynthesis of purine and pyrimidine nucleotides, the amino acids histidine and tryptophan, and the cofactors NAD and NADP .

HY-N0680R

Thiamine hydrochloride (Standard) Thiamine chloride hydrochloride (Standard); Vitamin B1 hydrochloride (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Source classification Endogenous metabolite	Bacterial Endogenous Metabolite HBV Apoptosis
Thiamine (hydrochloride) (Standard) is the analytical standard of Thiamine (hydrochloride). This product is intended for research and analytical applications. Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes .

HY-113402

Gamma-glutamylcysteine γ-Glu-Cys	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Gamma-glutamylcysteine (γ-Glutamylcysteine), a dipeptide containing cysteine and glutamic acid, is a precursor to glutathione (GSH). Gamma-glutamylcysteine is a cofactor for glutathione peroxidase (GPx) to increase GSH levels .

HY-147061

2-Deoxyribose 5-phosphate disodium	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Others
2-Deoxyribose 5-phosphate disodium is a substrate of 2-deoxyribose-5-phosphate aldolase (DERA). DERA belongs to the class I aldolases and catalyzes the reversible aldol condensation reaction without any cofactors .

HY-18733R

Lipoic acid (Standard) 5+ Cited Publications (R)-(+)-α-Lipoic acid(Standard); R-(+)-Thioctic acid (Standard)	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Mitochondrial Metabolism Endogenous Metabolite Reactive Oxygen Species
Lipoic acid (Standard) is the analytical standard of Lipoic acid. This product is intended for research and analytical applications. Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid.

HY-100196A

Pyrroloquinoline quinone disodium salt 2 Publications Verification PQQ disodium salt; Methoxatin disodium salt	Quinones Structural Classification Microorganisms Classification of Application Fields Source classification Benzene Quinones Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Pyrroloquinoline quinone disodium salt, a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone disodium salt is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone disodium salt is an essential nutrient for mammals and is important for immune function .

HY-A0124A

Sapropterin dihydrochloride 1 Publications Verification (6R)-BH4 dihydrochloride; (6R)-Tetrahydro-L-biopterin dihydrochloride	Cardiovascular Disease Classification of Application Fields Disease Research Fields	Others
Sapropterin ((6R)-BH4) is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin also drives autoimmunity. Sapropterin can be used in study of phenylketonuria (PKU) .

HY-113076

Thiamine pyrophosphate	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Thiamine pyrophosphate is the coenzyme form of Vitamin B1, and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex. Thiamine pyrophosphate is necessary for oxidative phosphorylation and the pentose phosphate pathway by acting as a cofactor for α-ketoacid dehydrogenases .

HY-B0152

Adenine 5+ Cited Publications 6-Aminopurine; Vitamin B4	Structural Classification Natural Products Microorganisms Classification of Application Fields Endogenous metabolite Disease Research Fields Cancer	DNA/RNA Synthesis Endogenous Metabolite
Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-B0152A

Adenine hydrochloride 5+ Cited Publications 6-Aminopurine hydrochloride; Vitamin B4 hydrochloride	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	DNA/RNA Synthesis Endogenous Metabolite
Adenine hydrochloride (6-Aminopurine hydrochloride), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hydrochloride acts as a chemical component of DNA and RNA. Adenine hydrochloride also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-B0152B

Adenine hemisulfate 5+ Cited Publications 6-Aminopurine hemisulfate; Vitamin B4 hemisulfate	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	DNA/RNA Synthesis Endogenous Metabolite
Adenine hemisulfate (6-Aminopurine hemisulfate), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hemisulfate acts as a chemical component of DNA and RNA. Adenine hemisulfate also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-B1746

Pyridoxamine 5′-phosphate	Structural Classification Alkaloids Human Gut Microbiota Metabolites Neurological Disease Classification of Application Fields Source classification Pyridine Alkaloids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Pyridoxamine 5′-phosphate is the active form of vitamin B6 bound to phosphoric acid. Pyridoxamine 5′-phosphate is the aminated form of pyridoxal 5'-phosphate hydrate (HY-W011727A) and as co-factor of a variety of enzymes central metabolite, potent antioxidant, vitamin B6 vitamer and enzyme substrate. Pyridoxamine 5′-phosphate can be interconverted with pyridoxal 5'-phosphate hydrate .

HY-B0399

L-Carnitine Maximum Cited Publications 10 Publications Verification (R)-Carnitine; Levocarnitine	Structural Classification Natural Products Neurological Disease Source classification Endocrine diseases Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms Immune System Disorder Disease markers Nervous System Disorder Disease Research Fields Cancer	Endogenous Metabolite
L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-B2246

L-Carnitine hydrochloride Maximum Cited Publications 10 Publications Verification (R)-Carnitine hydrochloride; Levocarnitine hydrochloride	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-B0152R

Adenine (Standard) 6-Aminopurine (Standard); Vitamin B4 (Standard)	Structural Classification Natural Products Microorganisms Endogenous metabolite	DNA/RNA Synthesis Endogenous Metabolite
Adenine (Standard) is the analytical standard of Adenine. This product is intended for research and analytical applications. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-W011727A

Pyridoxal 5'-phosphate monohydrate 1 Publications Verification Pyridoxal phosphate monohydrate	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP) .

HY-112234

L-Sepiapterin Sepiapterin	Alkaloids Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
L-Sepiapterin (Sepiapterin) is a precursor of the endothelial nitric oxide synthase (eNOS) cofactor tetrahydrobiopterin (BH4). L-Sepiapterin improves endothelial dysfunction in small mesenteric arteries from db/db mice, and induces angiogenesis. L-Sepiapterin inhibits cell proliferation and migration of ovarian cancer cells via down-regulation of p70 ^S6K-dependent VEGFR-2 expression .

HY-N9480

Vinaxanthone SM-345431	Structural Classification Microorganisms Xanthones Classification of Application Fields Source classification Phenols Disease Research Fields Cancer	Phospholipase Bacterial
Vinaxanthone (SM-345431) is a potent and selective semaphorin3A, phospholipase C (PLC) and FabI inhibitor, with IC₅₀s of 0.1-0.2 μM and 0.9 mM for semaphorin3A and FabI. Vinaxanthone inhibits the substrate (t-o-NAC thioester) and the cofactor (NADPH) with K_is of 3.1 μM and 1.0 μM, respectively. Vinaxanthone can be used to handle infections caused by multidrug-resistant pathogens .

HY-N1356A

(R)-Reticuline	Structural Classification Alkaloids Source classification Plants Lauraceae Isoquinoline Alkaloids Lindera aggregata (Sims) Kosterm.	Others
(R)-Reticuline is an isomer of Reticuline (HY-N1356). Reticuline displays anti-inflammatory and cardiovascular effects through JAK2/STAT3 and NF-κB signaling pathways. Salutaridine is a key intermediate in morphine biosynthesis. Salutaridine can be converted from (R)-Reticuline in the poppy plant. The conversion system relies on membrane-bound cytochrome P-450 enzymes and also requires reducing cofactors NADPH, molecular oxygen, etc .

HY-113402A

Gamma-glutamylcysteine TFA γ-Glutamylcysteine TFA	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Interleukin Related TNF Receptor Endogenous Metabolite
Gamma-glutamylcysteine (γ-Glutamylcysteine) TFA, an intermediate in glutathione (GSH) synthesis, is a dipeptide served as an essential cofactor for the antioxidant enzyme glutathione peroxidase (GPx). Gamma-glutamylcysteine TFA also upregulates the level of the anti-inflammatory cytokine IL-10 and reduces the levels of the pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β). Gamma-glutamylcysteine TFA attenuates the changes in metalloproteinase activity in oligomeric Aβ40-treated astrocytes .

HY-N0492R

α-Lipoic Acid (Standard) 5 Publications Verification Thioctic acid (Standard); (±)-α-Lipoic acid (Standard); DL-α-Lipoic acid (Standard)	Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	NF-κB HIV Mitochondrial Metabolism Endogenous Metabolite Apoptosis
α-Lipoic Acid (Standard) is the analytical standard of α-Lipoic Acid. This product is intended for research and analytical applications. α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .

Cat. No.	Product Name	Chemical Structure

HY-N0680S1

Thiamine-d3 hydrochloride
Thiamine-d₃ (hydrochloride) is the deuterium labeled Thiamine hydrochloride. Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-B0511S

Biotin-d2-1

Biotin-d₂-1 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.
HY-B0511S1

rel-Biotin-d4

rel-Biotin-d₄ is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.
HY-B0511S2

Biotin-d2

Biotin-d₂ is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.

HY-N0680S2

Thiamine-d4 hydrochloride
Thiamine-d₄ (hydrochloride) is deuterium labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-N0680S

Thiamine monochloride-13C hydrochloride
Thiamine monochloride- ¹³C₄ (hydrochloride) is the deuterium labeled Thiamine hydrochloride. Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-N0680S3

Thiamine-13C3 hydrochloride
Thiamine- ¹³C₃ (hydrochloride) is the ¹³C-labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-N0111S2

Coenzyme Q10-d9

Coenzyme Q10-d₉ is the deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.
HY-N0111S

Coenzyme Q10-d6

Coenzyme Q10-d₆ is deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-B1654S

Flavin adenine dinucleotide-13C5 ammonium
Flavin adenine dinucleotide- ¹³C5 (FAD- ¹³C5) ammonium is ¹³C labeled Flavin adenine dinucleotide (HY-B1654). Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

HY-100196S1

Pyrroloquinoline quinone-13C3 sodium
Pyrroloquinoline quinone-13C3 (sodium) is an isotope of Pyrroloquinoline quinone. Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function .

HY-B0230S2

Phenylbutazone-13C12
Phenylbutazone- ¹³C₁₂ is the ¹³C₁₂ labeled Phenylbutazone. Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agent (NSAID). Phenylbutazone induces muscle blind-like protein 1 (MBNL1) expression and has the potential for ankylosing spondylitis research.

HY-B0230S

Phenylbutazone(diphenyl-d10)

Phenylbutazone(diphenyl-d₁₀) is the deuterium labeled Phenylbutazone. Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agent (NSAID). Phenylbutazone induces muscle blind-like protein 1 (MBNL1) expression and has the potential for ankylosing spondylitis research[1][2].

HY-B0230S1

Phenylbutazone-d9
Phenylbutazone-d₉ is the deuterium labeled Phenylbutazone. Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agent (NSAID). Phenylbutazone induces muscle blind-like protein 1 (MBNL1) expression and has the potential for ankylosing spondylitis research[1][2].

HY-B0152S

Adenine-d1
Adenine-d is the deuterium labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis[1][2][3].

HY-B0152S1

Adenine-13C
Adenine- ¹³C is the ¹³C labeled Adenine[1]. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis[2][3][4].

HY-N0492S

α-Lipoic Acid-d5
α-Lipoic Acid-d₅ is the deuterium labeled α-Lipoic Acid. α-Lipoic Acid is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation[1][2][3]. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells[4].

HY-10235S

Telaprevir-d4
Telaprevir-d₄ is the deuterium labeled Telaprevir. Telaprevir (VX-950) is a highly selective, reversible, and potent peptidomimetic inhibitor of the HCV NS3-4A protease, the steady-state inhibitory constant (Ki) of Telaprevir is 7 nM against a genotype 1 (H strain) NS3 protease domain plus a NS4A cofactor peptide[1][2][3]. Telaprevir inhibits SARS-CoV-2 3CLpro activity[4].

HY-B2246S

L-Carnitine-d9 chloride

L-Carnitine-d₉ (chloride)e is the deuterium labeled L-Carnitine chloride. L-Carnitine chloride, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine chloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine chloride is an antioxidant. L-Carnitine chloride can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2][3].

HY-B0152S3

Adenine-13C5

Adenine- ¹³C₅ (6-Aminopurine- ¹³C₅; Vitamin B4- ¹³C₅) is ¹³C-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

HY-B0152S4

Adenine-15N5

Adenine- ¹⁵N₅ (6-Aminopurine- ¹⁵N₅; Vitamin B4- ¹⁵N₅) is ¹⁵N labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

HY-112499S

Menaquinone-7-d7

Menaquinone-7-d₇ is the deuterium labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3].

HY-112499S1

Menaquinone-7-13C6

Menaquinone-7- ¹³C₆ is the ¹³C-labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3].

HY-B0152S2

Adenine-13C5,15N5

Adenine- ¹³C₅,15C5 (6-Aminopurine- ¹³C₅,15C5; Vitamin B4- ¹³C₅,15C5) is ¹³C-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

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