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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

conjugates

" in MCE Product Catalog:

By Targets:	ADC Linker (675) Antibody-Drug Conjugates (ADCs) (26) Drug-Linker Conjugates for ADC (168) E3 Ligase Ligand-Linker Conjugates (278) PROTAC-Linker Conjugates for PAC (3) Target Protein Ligand-Linker Conjugates (11) ADC Antibody (13) ADC Cytotoxin (62) Akt (2) ALCAM/CD166 (1) Amino Acid Derivatives (3) Aminopeptidase (2) Amyloid-β (1) Antibiotic (2) Antifolate (1) Apoptosis (17) AUTACs (2) Autophagy (2) Bacterial (13) Bcr-Abl (12) Biochemical Assay Reagents (5) c-Myc (1) Casein Kinase (1) CCR (1) CD19 (1) CD22 (2) Checkpoint Kinase (Chk) (1) Cholinesterase (ChE) (1) CMV (1) Complement System (2) CXCR (2) Cytochrome P450 (1) DNA Alkylator/Crosslinker (13) DNA/RNA Synthesis (9) Dopamine Receptor (1) Drug Metabolite (2) E1/E2/E3 Enzyme (3) EGFR (13) Endogenous Metabolite (35) Ephrin Receptor (1) Epigenetic Reader Domain (7) Estrogen Receptor/ERR (5) FAP (1) Fatty Acid Synthase (FASN) (1) Ferroptosis (1) Fluorescent Dye (36) Fungal (1) Glucocorticoid Receptor (2) Guanylate Cyclase (1) HBV (2) HDAC (1) HIF/HIF Prolyl-Hydroxylase (2) Histone Acetyltransferase (1) HIV (4) HSP (3) HSV (1) IGF-1R (1) Influenza Virus (1) Integrin (3) Interleukin Related (3) Isotope-Labeled Compounds (5) Ligands for E3 Ligase (1) Ligands for Target Protein for PROTAC (1) Liposome (10) LXR (1) MDM-2/p53 (2) Mesothelin (1) MicroRNA (1) Microtubule/Tubulin (37) Mitochondrial Metabolism (4) Mitophagy (1) NAMPT (3) Neurokinin Receptor (1) Notch (1) Nucleoside Antimetabolite/Analog (2) Orthopoxvirus (1) P2Y Receptor (1) Parasite (2) PD-1/PD-L1 (2) PI3K (1) PKC (2) PPAR (1) PROTAC Linkers (210) PROTACs (15) RAR/RXR (1) Reactive Oxygen Species (1) SARS-CoV (1) Ser/Thr Protease (1) Small Interfering RNA (siRNA) (4) SNIPERs (13) STAT (1) Stearoyl-CoA Desaturase (SCD) (1) STING (9) TAM Receptor (3) TNF Receptor (3) Toll-like Receptor (TLR) (6) Topoisomerase (7) Transthyretin (TTR) (1)
By Research Areas:	Cancer (1314) Cardiovascular Disease (4) Endocrinology (3) Infection (27) Inflammation/Immunology (60) Metabolic Disease (28) Neurological Disease (13)

By Targets:

ADC Linker (675)

Antibody-Drug Conjugates (ADCs) (26)

Drug-Linker Conjugates for ADC (168)

E3 Ligase Ligand-Linker Conjugates (278)

PROTAC-Linker Conjugates for PAC (3)

Target Protein Ligand-Linker Conjugates (11)

ADC Antibody (13)

ADC Cytotoxin (62)

Akt (2)

ALCAM/CD166 (1)

Amino Acid Derivatives (3)

Aminopeptidase (2)

Amyloid-β (1)

Antibiotic (2)

Antifolate (1)

Apoptosis (17)

AUTACs (2)

Autophagy (2)

Bacterial (13)

Bcr-Abl (12)

Biochemical Assay Reagents (5)

c-Myc (1)

Casein Kinase (1)

CCR (1)

CD19 (1)

CD22 (2)

Checkpoint Kinase (Chk) (1)

Cholinesterase (ChE) (1)

CMV (1)

Complement System (2)

CXCR (2)

Cytochrome P450 (1)

DNA Alkylator/Crosslinker (13)

DNA/RNA Synthesis (9)

Dopamine Receptor (1)

Drug Metabolite (2)

E1/E2/E3 Enzyme (3)

EGFR (13)

Endogenous Metabolite (35)

Ephrin Receptor (1)

Epigenetic Reader Domain (7)

Estrogen Receptor/ERR (5)

FAP (1)

Fatty Acid Synthase (FASN) (1)

Ferroptosis (1)

Fluorescent Dye (36)

Fungal (1)

Glucocorticoid Receptor (2)

Guanylate Cyclase (1)

HBV (2)

HDAC (1)

HIF/HIF Prolyl-Hydroxylase (2)

Histone Acetyltransferase (1)

HIV (4)

HSP (3)

HSV (1)

IGF-1R (1)

Influenza Virus (1)

Integrin (3)

Interleukin Related (3)

Isotope-Labeled Compounds (5)

Ligands for E3 Ligase (1)

Ligands for Target Protein for PROTAC (1)

Liposome (10)

LXR (1)

MDM-2/p53 (2)

Mesothelin (1)

MicroRNA (1)

Microtubule/Tubulin (37)

Mitochondrial Metabolism (4)

Mitophagy (1)

NAMPT (3)

Neurokinin Receptor (1)

Notch (1)

Nucleoside Antimetabolite/Analog (2)

Orthopoxvirus (1)

P2Y Receptor (1)

Parasite (2)

PD-1/PD-L1 (2)

PI3K (1)

PKC (2)

PPAR (1)

PROTAC Linkers (210)

PROTACs (15)

RAR/RXR (1)

Reactive Oxygen Species (1)

SARS-CoV (1)

Ser/Thr Protease (1)

Small Interfering RNA (siRNA) (4)

SNIPERs (13)

STAT (1)

Stearoyl-CoA Desaturase (SCD) (1)

STING (9)

TAM Receptor (3)

TNF Receptor (3)

Toll-like Receptor (TLR) (6)

Topoisomerase (7)

Transthyretin (TTR) (1)

By Research Areas:

Cancer (1314)

Cardiovascular Disease (4)

Endocrinology (3)

Infection (27)

Inflammation/Immunology (60)

Metabolic Disease (28)

Neurological Disease (13)

1483

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Antibody-Drug Conjugates (ADCs) Target Protein Ligand-Linker Conjugates PROTAC-Linker Conjugates for PAC Drug-Linker Conjugates for ADC ADC Linker E3 Ligase Ligand-Linker Conjugates

Cat. No.	Product Name	Target	Research Areas

HY-130270

*AhR Ligand-Linker Conjugates* 1** E3 Ligase Ligand-Linker conjugates 57	E3 Ligase Ligand-Linker Conjugates	Cancer
AhR Ligand-Linker Conjugates 1 (E3 Ligase Ligand-Linker Conjugates 57) incorporates an IAP ligand for the E3 ubiquitin ligase, and a SNIPER linker. AhR Ligand-Linker Conjugates 1 can be used to design SNIPER.

HY-125906

*VHL Ligand-Linker Conjugates* 15** E3 Ligase Ligand-Linker conjugates 56	E3 Ligase Ligand-Linker Conjugates	Cancer
VHL Ligand-Linker Conjugates 15 incorporates an VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. VHL Ligand-Linker Conjugates 15 can be used to design PROTACs.

HY-139655

*cIAP1 Ligand-Linker Conjugates* 16**	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 16 is an E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACs.

HY-128822

*cIAP1 Ligand-Linker Conjugates* 13** E3 ligase Ligand-Linker conjugates 43	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 13 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 13 can be used to design SNIPERs.

HY-128813A

*cIAP1 Ligand-Linker Conjugates* 15 hydrochloride** E3 ligase Ligand-Linker conjugates 34 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 15 hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 15 hydrochloride can be used to design SNIPERs.

HY-128815

*cIAP1 Ligand-Linker Conjugates* 14** E3 ligase Ligand-Linker conjugates 36	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 14 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 14 can be used to design SNIPERs.

HY-128816A

*cIAP1 Ligand-Linker Conjugates* 2 Hydrochloride** E3 ligase Ligand-Linker conjugates 37 Hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 2 Hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 2 Hydrochloride can be used to design SNIPERs.

HY-128820

*cIAP1 Ligand-Linker Conjugates* 1** E3 ligase Ligand-Linker conjugates 41	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 1 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 1 can be used to design SNIPERs.

HY-128819

*cIAP1 Ligand-Linker Conjugates* 3** E3 ligase Ligand-Linker conjugates 40	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 3 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 3 can be used to design SNIPERs.

HY-128826

*cIAP1 Ligand-Linker Conjugates* 10** E3 ligase Ligand-Linker conjugates 47	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 10 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 10 can be used to design SNIPERs.

HY-128812A

*cIAP1 Ligand-Linker Conjugates* 11 Hydrochloride** E3 ligase Ligand-Linker conjugates 33 Hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 11 Hydrochloride can be used to design SNIPERs.

HY-128813

*cIAP1 Ligand-Linker Conjugates* 15** E3 ligase Ligand-Linker conjugates 34	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 15 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 15 can be used to design SNIPERs.

HY-128824

*cIAP1 Ligand-Linker Conjugates* 9** E3 ligase Ligand-Linker conjugates 45	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 9 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 9 can be used to design SNIPERs.

HY-128812

*cIAP1 Ligand-Linker Conjugates* 11** E3 ligase Ligand-Linker conjugates 33	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 11 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 11 can be used to design SNIPERs.

HY-128817

*cIAP1 Ligand-Linker Conjugates* 12** E3 ligase Ligand-Linker conjugates 38	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 12 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 12 can be used to design SNIPERs.

HY-128825

*cIAP1 Ligand-Linker Conjugates* 8** E3 ligase Ligand-Linker conjugates 46	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 8 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 8 can be used to design SNIPERs.

HY-128823

*cIAP1 Ligand-Linker Conjugates* 7** E3 ligase Ligand-Linker conjugates 44	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 7 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 7 can be used to design SNIPERs.

HY-128818

*cIAP1 Ligand-Linker Conjugates* 5** E3 ligase Ligand-Linker conjugates 39	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 5 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 5 can be used to design SNIPERs.

HY-128821

*cIAP1 Ligand-Linker Conjugates* 4** E3 ligase Ligand-Linker conjugates 42	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 4 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 4 can be used to design SNIPERs.

HY-128816

*cIAP1 Ligand-Linker Conjugates* 2** E3 ligase Ligand-Linker conjugates 37	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 2 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 2 can be used to design SNIPERs.

HY-128814

*cIAP1 Ligand-Linker Conjugates* 6 hydrochloride** E3 ligase Ligand-Linker conjugates 35 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 6 hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 6 hydrochloride can be used to design SNIPERs.

HY-128941

*CCK2R Ligand-Linker Conjugates* 1**	Drug-Linker Conjugates for ADC	Cancer
CCK2R Ligand-Linker Conjugates 1 is a ligand-linker conjugate, which conjugates to the cytotoxic antimicrotubule agents Desacetyl Vinblastine Hydrazide (DAVBH) and Tubulysin B Hydrazide (TubBH) via a hydrophilic peptide linker.

HY-133046

*VHL Ligand-Linker Conjugates* 17**	E3 Ligase Ligand-Linker Conjugates	Cancer
VHL Ligand-Linker Conjugates 17 incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. VHL Ligand-Linker Conjugates 17 can be used in the synthesis of a series of PROTACs, such as ARD-266 (HY-133020). ARD-266 is a highly potent androgen receptor (AR) PROTAC degrader.

HY-130499

*ERRα Ligand-Linker Conjugates* 1**	Target Protein Ligand-Linker Conjugates	Cancer
ERRα Ligand-Linker Conjugates 1 incorporates a ligand for estrogen-related receptor alpha (ERRα), and a PROTAC linker, which recruit E3 ligases MDM2. ERRα Ligand-Linker Conjugates 1 can be used in the synthesis of a series of PROTACs, such as PROTAC ERRalpha Degrader-1 (HY-128838). PROTAC ERRalpha Degrader-1 is an ERRα degrader.

HY-107439

Thalidomide-O-amido-C8-NH2 Cereblon Ligand-Linker conjugates 2; E3 Ligase Ligand-Linker conjugates 20	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.

HY-107438

Thalidomide-O-amido-C4-NH2 Cereblon Ligand-Linker conjugates 6; E3 Ligase Ligand-Linker conjugates 19	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amido-C4-NH2 (Cereblon Ligand-Linker Conjugates 6), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.

HY-111824

VH032-thiol-C6-NH2 VHL Ligand-Linker conjugates 14; E3 ligase Ligand-Linker conjugates 29	E3 Ligase Ligand-Linker Conjugates	Cancer
VH032-thiol-C6-NH2 (VHL Ligand-Linker Conjugates 14) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology.

HY-112618

Thalidomide-O-amido-C6-NH2 Cereblon Ligand-Linker conjugates 11; E3 Ligase Ligand-Linker conjugates 25	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amido-C6-NH2 (Cereblon Ligand-Linker Conjugates 11), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.

HY-128716B

Pomalidomide-PEG3-C2-NH2 hydrochloride Cereblon Ligand-Linker conjugates 5 hydrochloride; E3 ligase Ligand-Linker conjugates 30 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-147225

*TSPO Ligand-Linker Conjugates* 1**	AUTACs Mitophagy	Cancer Metabolic Disease Neurological Disease
TSPO Ligand-Linker Conjugates 1 contains a ligand for translocator protein (TSPO) and a linker, which is used for the synthesis of mitochondria-targeting autophagy-targeting chimera (AUTAC). AUTAC can bind the TSPO on the outer mitochondrial membrane (OMM) of mitochondria and degrades impaired mitochondria and proteins via mitophagy, and improves mitochondrial activity. TSPO Ligand-Linker Conjugates 1 can be used in mitochondrial dysfunction related research, including neurodegenerative diseases, cancer, and diabetes.

HY-103614

Thalidomide-O-amido-C8-NH2 TFA Cereblon Ligand -Linker conjugates 2 TFA; E3 Ligase Ligand-Linker conjugates 20 TFA	E3 Ligase Ligand-Linker Conjugates	Others
Thalidomide-O-amido-C8-NH2 TFA (Cereblon Ligand -Linker Conjugates 2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-103613

Thalidomide-O-amido-C4-NH2 TFA Cereblon Ligand-Linker conjugates 6 TFA; E3 ligase Ligand-Linker conjugates 19 TFA	E3 Ligase Ligand-Linker Conjugates	Others
Thalidomide-O-amido-C4-NH2 TFA (Cereblon Ligand-Linker Conjugates 6 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-130521

Pomalidomide-amido-PEG3-C2-NH2 Cereblon Ligand-Linker conjugates 22; E3 ligase Ligand-Linker conjugates 55	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 22) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

HY-107440

Thalidomide-O-amido-PEG3-C2-NH2 Cereblon Ligand-Linker conjugates 3 ; E3 Ligase Ligand-Linker conjugates 14	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

HY-112618A

Thalidomide-O-amido-C6-NH2 TFA Cereblon Ligand-Linker conjugates 11 TFA; E3 Ligase Ligand-Linker conjugates 25 TFA	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.

HY-103612

Thalidomide-O-amido-C3-COOH Cereblon Ligand-Linker conjugates 7; E3 ligase Ligand-Linker conjugates 15	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amido-C3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-21930

Pomalidomide-PEG4-C-COOH Cereblon Ligand -Linker conjugates 1; E3 Ligase Ligand-Linker conjugates 1	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG4-C-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

HY-115560

Thalidomide-O-amido-C3-NH2 Cereblon Ligand-Linker conjugates 16; E3 Ligase Ligand-Linker conjugates 52	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amido-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-103615

Thalidomide-O-amido-C4-N3 Cereblon Ligand-Linker conjugates 4; E3 ligase Ligand-Linker conjugates 18	E3 Ligase Ligand-Linker Conjugates	Others
Thalidomide-O-amido-C4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-41549

Pomalidomide-PEG4-Ph-NH2 Cereblon Ligand-Linker conjugates 9; E3 Ligase Ligand-Linker conjugates 2	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG4-Ph-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

HY-126458

Thalidomide-O-PEG2-propargyl E3 ligase Ligand-Linker conjugates 32	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.

HY-128716A

Pomalidomide-PEG3-C2-NH2 TFA Cereblon Ligand-Linker conjugates 5 TFA; E3 ligase Ligand-Linker conjugates 30 TFA	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 5 (TFA)) is a synthetic E3 ligase ligand-linker conjugate comprising a Pomalidomide (HY-10984)-based cereblon ligand and a 3-unit PEG linker. Pomalidomide-PEG3-C2-NH2 TFA can be used for the synthesis of PROTACs.

HY-128716

Pomalidomide-PEG3-C2-NH2 Cereblon Ligand-Linker conjugates 5; E3 ligase Ligand-Linker conjugates 30	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

HY-112599

Pomalidomide-PEG4-C2-NH2 Cereblon Ligand-Linker conjugates 8; E3 Ligase Ligand-Linker conjugates 22	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

HY-125884

Pomalidomide-amido-C4-amido-C6-NH-Boc Cereblon Ligand-Linker conjugates 21; E3 Ligase Ligand-Linker conjugates 54	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-amido-C4-amido-C6-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-115560A

Thalidomide-O-amido-C3-NH2 TFA Cereblon Ligand-Linker conjugates 16 TFA; E3 Ligase Ligand-Linker conjugates 52 TFA	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amido-C3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-128846A

Pomalidomide-C2-NH2 hydrochloride Cereblon Ligand-Linker conjugates 15 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-128846

Pomalidomide-C2-NH2 Cereblon Ligand-Linker conjugates 15	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a PEG linker used in PROTAC technology.

HY-125846

(S,R,S)-AHPC-PEG1-OTs VH032-PEG1-OTs; VHL Ligand-Linker conjugates 2; E3 ligase Ligand-Linker conjugates 51	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG1-OTs is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 1-unit PEG linker used in PROTAC technology.

HY-125883

Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc Cereblon Ligand-Linker conjugates 20; E3 Ligase Ligand-Linker conjugates 53	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.

HY-112617A

Thalidomide-O-amido-PEG2-C2-NH2 TFA Cereblon Ligand-Linker conjugates 10 TFA; E3 Ligase Ligand-Linker conjugates 24 TFA	E3 Ligase Ligand-Linker Conjugates	Cancer Inflammation/Immunology
Thalidomide-O-amido-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.

HY-103611

Thalidomide-O-amido-PEG3-C2-NH2 TFA Cereblon Ligand-Linker conjugates 3 TFA; E3 ligase Ligand-Linker conjugates 14 TFA	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

HY-128832

Nutlin-C1-amido-PEG4-C2-N3 MDM2 Ligand-Linker conjugates 1; E3 ligase Ligand-Linker conjugates 48	E3 Ligase Ligand-Linker Conjugates	Cancer
Nutlin-C1-amido-PEG4-C2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Nutlin 3 based MDM2 ligand and 4-unit PEG linker used in PROTAC technology.

HY-114176

(S,R,S)-AHPC-C4-NH2 hydrochloride VH032-C4-NH2 hydrochloride; VHL Ligand-Linker conjugates 13; E3 ligase Ligand-Linker conjugates 28	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC.

HY-103599

(S,R,S)-AHPC-PEG2-N3 VH032-PEG2-N3; VHL Ligand-Linker conjugates 6; E3 ligase Ligand-Linker conjugates 13	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in PROTAC technology.

HY-103604

(S,R,S)-AHPC-PEG4-NH2 hydrochloride VH032-PEG4-NH2 hydrochloride; VHL Ligand-Linker conjugates 4 hydrochloride; E3 ligase Ligand-Linker conjugates 7	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.

HY-103601

(S,R,S)-AHPC-PEG4-N3 VH032-PEG4-N3; VHL Ligand-Linker conjugates 5; E3 ligase Ligand-Linker conjugates 4	E3 Ligase Ligand-Linker Conjugates	Others
(S,R,S)-AHPC-PEG4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.

HY-103600

(S,R,S)-AHPC-PEG1-N3 VH032-PEG1-N3; VHL Ligand-Linker conjugates 9; E3 ligase Ligand-Linker conjugates 3	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG1-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 1-unit PEG linker used in PROTAC technology.

HY-103598

(S,R,S)-AHPC-PEG3-N3 VH032-PEG3-N3; VHL Ligand-Linker conjugates 8; E3 ligase Ligand-Linker conjugates 12	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG3-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology.

HY-103602

(S,R,S)-AHPC-PEG3-NH2 hydrochloride VH032-PEG3-NH2 hydrochloride; VHL Ligand-Linker conjugates 1 hydrochloride; E3 ligase Ligand-Linker conjugates 5	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology.

HY-130271

(S,R,S)-AHPC-PEG5-COOH VH032-PEG5-COOH; VHL Ligand-Linker conjugates 16; E3 Ligase Ligand-Linker conjugates 58	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 5-unit PEG linker used in PROTAC technology.

HY-112600

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 Cereblon Ligand-Linker conjugates 12; E3 Ligase Ligand-Linker conjugates 23	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-128848

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH Cereblon Ligand-Linker conjugates 14; E3 ligase Ligand-Linker conjugates 49	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-103602A

(S,R,S)-AHPC-PEG3-NH2 VH032-PEG3-NH2; VHL Ligand-Linker conjugates 1; E3 ligase Ligand-Linker conjugates 5 Free Base	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology.

HY-103604A

(S,R,S)-AHPC-PEG4-NH2 VH032-PEG4-NH2; VHL Ligand-Linker conjugates 4 ; E3 ligase Ligand-Linker conjugates 7 Free Base	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.

HY-125843

Pomalidomide-PEG1-C2-N3 Cereblon Ligand-Linker conjugates 13; E3 ligase Ligand-Linker conjugates 50	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG1-C2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 1-unit PEG linker used in PROTAC technology. Pomalidomide-PEG1-C2-N3 can be used to design a selective CDK6 PROTAC degrader CP-10. CP-10 induces the degradation of CDK6 with an DC₅₀ of 2.1 nM.

HY-103603

(S,R,S)-AHPC-PEG2-NH2 hydrochloride VH032-PEG2-NH2 hydrochloride; VHL Ligand-Linker conjugates 3 hydrochloride; E3 ligase Ligand-Linker conjugates 6	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG2-NH2 hydrochloride (VH032-PEG2-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs.

HY-112600A

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 TFA Cereblon Ligand-Linker conjugates 12 TFA; E3 Ligase Ligand-Linker conjugates 23 TFA	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

HY-103603A

(S,R,S)-AHPC-PEG2-NH2 VH032-PEG2-NH2 ; VHL Ligand-Linker conjugates 3 ; E3 ligase Ligand-Linker conjugates 6 Free Base	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs.

HY-P4198

Fmoc-N(Me)-Sar10
Biochemical Assay Reagents Others

Fmoc-N(Me)-Sar10 can be used for synthesis of peptide ligand-drug conjugates.
HY-150074

STING agonist-18
Others Cancer

STING agonist-18 (compound 1a) can be used for synthesis of antibody-drug conjugates (ADCs), such Trastuzumab (HY-P9907) conjugate.

HY-139957

Mal-amido-PEG8-Val-Ala-PAB-SG3200	Drug-Linker Conjugates for ADC	Others
Mal-amido-PEG8-Val-Ala-PAB-SG3200 is a *conjugate* for antibody-drug conjugate (ADC) (extracted from patent WO2016166300A1).

HY-103606

(S,R,S)-AHPC-PEG6-C4-Cl VH032-PEG6-C4-Cl; VHL Ligand-Linker conjugates 10; E3 ligase Ligand-Linker conjugates 9	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG6-C4-Cl is a conjugate of ligands for E3 and 25-atom-length linker. The connector of linker is Halogen group. (S,R,S)-AHPC-PEG6-C4-Cl incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays.

HY-103607

(S,R,S)-AHPC-PEG2-C4-Cl VH032-PEG2-C4-Cl; VHL Ligand-Linker conjugates 7; E3 ligase Ligand-Linker conjugates 10	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG2-C4-Cl (VH032-PEG2-C4-Cl) is a conjugate of ligands for E3 and 13-atom-length linker. The connector of linker is Halogen group. (S,R,S)-AHPC-PEG2-C4-Cl incorporates the (S,R,S)-AHPC based VHL ligand and an alkyl/ether-based linker. (S,R,S)-AHPC-PEG2-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays.

HY-147118

NHS-SS-Ph
ADC Linker Cancer

NHS-SS-Ph is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-151741

Biotin-PEG4-MeTz	ADC Linker	Others
Biotin-PEG4-MeTz is a click chemistry reagent containing a terminal methyltetrazine group that reacts with trans-cyclooctene. Biotin-PEG4-MeTz can be used for the preparation of biotinylated conjugates.

HY-136261

DM1-PEG4-DBCO	Drug-Linker Conjugates for ADC	Cancer
DM1-(PEG)4-DBCO is a drug-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody drug conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.

HY-139245

MC-Ala-Ala-Asn-PAB	ADC Linker	Cancer
MC-Ala-Ala-Asn-PAB is a linker extracted from patent CN104147612A, page 14. MC-Ala-Ala-Asn-PAB can be used to synthesis the tumor microenvironment specific activated micromolecular targeted conjugate.

HY-139909

CL2E-SN38	Drug-Linker Conjugates for ADC	Cancer
CL2E-SN-38, a highly releasable and structurally stable antibody-SN-38-conjugate, is a part of the antibody drug conjugate (ADC). SN-38, the active metabolite of Irinotecan from camptothecins, is an Topoisomerase I inhibitor.

HY-150075

STING agonist-19
Others Others

STING agonist-19 can be used to synthesize ISAC (immune-stimulating antibody conjugates) molecule.
HY-116270

DBCO-Maleimide
ADC Linker Cancer

DBCO-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-42973

DBCO-NHS ester
ADC Linker Cancer

DBCO-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W000423

DBCO-amine
ADC Linker Cancer

DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-139909A

CL2E-SN38 TFA	Drug-Linker Conjugates for ADC	Cancer
CL2E-SN-38 TFA, a highly releasable and structurally stable antibody-SN-38-conjugate, is a part of the antibody drug conjugate (ADC). SN-38, the active metabolite of Irinotecan from camptothecins, is an Topoisomerase I inhibitor.

HY-103605

(S,R,S)-AHPC-C6-PEG3-C4-Cl VH032-C6-PEG3-C4-Cl; VHL Ligand-Linker conjugates 12; E3 ligase Ligand-Linker conjugates 8	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C6-PEG3-C4-Cl (VH032-C6-PEG3-C4-Cl) is a conjugate of ligands for E3 and 20-atom-length linker. The connector of linker is Halogen group. (S,R,S)-AHPC-C6-PEG3-C4-Cl incorporates the (S,R,S)-AHPC based VHL ligand and an alkyl/ether-based linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays.

HY-138300

ALC-0159
Liposome Inflammation/Immunology

ALC-0159, a polyethylene glycol (PEG) lipid conjugate, could be used as vaccine excipient.
HY-23641

NH-bis(C1-Boc)
ADC Linker Cancer

NH-bis(C1-Boc)is a uncleavable linker used for antibody-drug conjugates (ADC).
HY-123687

DBCO-Sulfo-NHS ester sodium
ADC Linker Cancer

DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126517

Cyclooctyne-O-NHS ester
ADC Linker Cancer

Cyclooctyne-O-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-79129

Fmoc-D-Trp(Boc)-OH
ADC Linker Cancer

Fmoc-D-Trp(Boc)-OH is a cleavable ADC linker that used in the synthesis of antibody-drug conjugates (ADCs).
HY-W097109A

Fmoc-(D-Phe)-OSu
ADC Linker Cancer

Fmoc-(D-Phe)-Osu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130810

DBCO-Sulfo-Link-biotin
ADC Linker Cancer

DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130956

Boc-NMe-Val-Val-Dil-Dap-OH
ADC Linker Cancer

Boc-NMe-Val-Val-Dil-Dap-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130961

Boc-Val-Dil-Dap-OH
ADC Linker Cancer

Boc-Val-Dil-Dap-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130648

Thalidomide-NH-PEG7	Drug-Linker Conjugates for ADC E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-PEG7 is a synthesized E3 ligase ligand-linker conjugate for ADC. Thalidomide-NH-PEG7 can be connected to the ligand for protein by a linker to form PROTAC iRucaparib-AP6, a highly specific PARP1 degrader.

HY-W040236

m-PEG8-Amine
ADC Linker PROTAC Linkers Cancer

m-PEG8-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-78921

Fmoc-3VVD-OH
ADC Linker Cancer

Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130976

N-Boc-Val-Dil-Dap-Doe
ADC Linker Cancer

N-Boc-Val-Dil-Dap-Doe is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130975

Boc-Val-Dil-Dap-Phe-OMe
ADC Linker Cancer

Boc-Val-Dil-Dap-Phe-OMe is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-120770

DBCO-PEG4-Maleimide
ADC Linker Cancer

DBCO-PEG4-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-148820

Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (Formula V) is a drug-linker conjugate that composed of a potent topoisomerase I inhibitor and a linker to make antibody drug conjugate (ADC).

HY-147050

Ahx-DM1
Target Protein Ligand-Linker Conjugates Others

Ahx-DM1 (compound 2A) is a conjugate of protein/peptide which can be combined with a therapeutic, diagnostic or labelling agent.
HY-144013

18:0 PEG-PE
Liposome Others

18:0 PEG-PE is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:0 PEG-PE can be used for drug delivery.
HY-144010

18:1 PEG-PE
Liposome Others

18:1 PEG-PE is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:1 PEG-PE can be used for drug delivery.

HY-N11416

Glycodehydrocholic acid	Endogenous Metabolite	Cancer Endocrinology Metabolic Disease
Glycodehydrocholic acid is a bile acid glycine conjugate. Glycodehydrocholic acid is used to diagnose cancer and other diseases.

HY-147050A

Ahx-DM1 TFA	Target Protein Ligand-Linker Conjugates	Others
Ahx-DM1 (TFA) (compound 2A) is a conjugate of protein/peptide which can be combined with a therapeutic, diagnostic or labelling agent.

HY-148550

MC-PEG2-NH2
ADC Linker Cancer

MC-PEG2-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-145943

MP-PEG8-Val-Lys-Gly-7-MAD-MDCPT	Drug-Linker Conjugates for ADC	Cancer Inflammation/Immunology
MP-PEG8-Val-Lys-Gly-7-MAD-MDCPT is a drug-linker conjugate for antibody-drug conjugate (ADC). MP-PEG8-Val-Lys-Gly-7-MAD-MDCPT has the potential for cancer and autoimmune disease research.

HY-148425

Mal-amide-PEG8-Val-Ala-PAB-PNP
ADC Linker Cancer

Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130642

(S,R,S)-AHPC-Me-C10-Br	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-Me-C10-Br is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-Me-C10-Br incorporates a VHL E3 ligase linker and MS432 based on the MEK1/2 inhibitor PD0325901.

HY-141808

AZD-CO-Ph-PEG4-Ph-CO-AZD
Others Cancer

AZD-CO-Ph-PEG4-Ph-CO-AZD is a bis-β-lactam linker can be used for antibody-siRNA conjugate synthesis.

HY-147021

MC-Val-D-Cit-PAB-PNP	ADC Linker	Cancer
MC-Val-D-Cit-PAB-PNP is a cleavable peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs). MC-Val-D-Cit-PAB-PNP contains a maleimidocaproyl (Mc) group that can be conjugated to an antibody and a p-nitrophenol (PNP) group that allows the peptide to be linked to antitumor compounds.

HY-132261

AcBut
4-(4-Acetyl-phenoxy)-butyric acid
ADC Linker Cancer

AcBut is a cleavable Ozogamicin linker used in the synthesis of Ozogamicin, a drug-linker conjugate for ADC.

HY-148474

Mal-Val-Ala-PABA-cGAMP	ADC Linker	Cancer
Mal-Val-Ala-PABA-cGAMP is a ADC linker that can be connected to a STING agonist. Mal-Val-Ala-PABA-cGAMP can be used for the synthesis of antibody-drug conjugates (ADCs).

HY-W044078

N-Boc-diethanolamine	ADC Linker PROTAC Linkers	Cancer
N-Boc-diethanolamine is an Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-diethanolamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-101909

Val-Cit-PAB-MMAF	Drug-Linker Conjugates for ADC	Cancer
Val-Cit-PAB-MMAF is a *drug-linker conjugate* for ADC**. Val-Cit-PAB-MMAF contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin polymerization inhibitor MMAF (HY-15579)

HY-44177

Val-Cit-PAB-MMAF sodium	Drug-Linker Conjugates for ADC	Cancer
Val-Cit-PAB-MMAF sodium is a *drug-linker conjugate* for ADC**. Val-Cit-PAB-MMAF sodium contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin polymerization inhibitor MMAF (HY-15579)

HY-148057

TCO-PEG4-VC-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
TCO-PEG4-VC-PAB-MMAE is a *drug-linker conjugate* for ADC**. TCO-PEG4-VC-PAB-MMAE contains a cleavable ADC linker (TCO-PEG4-VC-PA) and a potent tubulin inhibitor MMAE (HY-15162).

HY-130383

Propargyl-PEG7-acid	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG7-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130386

Propargyl-PEG6-acid	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130166

Amino-PEG9-acid	ADC Linker PROTAC Linkers	Cancer
Amino-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG9-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-134983

Thalidomide-Piperazine 5-fluoride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-Piperazine 5-fluoride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-134669

CypK N-Cyclopropene-L-Lysine	Others	Cancer
CypK (N-Cyclopropene-L-Lysine), a cyclopropene derivative of lysine, is efficiently incorporated into antibodies through genetic-code expansion. CypK is a minimal bioorthogonal handle for the creation of stable therapeutic protein conjugates.

HY-141170

TCO-PEG12-NHS ester	ADC Linker PROTAC Linkers	Cancer
TCO-PEG12-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG12-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130457

m-PEG4-Ms	ADC Linker PROTAC Linkers	Cancer
m-PEG4-Ms is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-120237

m-PEG7-Amine	ADC Linker PROTAC Linkers	Cancer
m-PEG7-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG7-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130346

DBCO-PEG4-DBCO	ADC Linker PROTAC Linkers	Cancer
DBCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-141167

TCO-PEG4-NHS ester	ADC Linker PROTAC Linkers	Cancer
TCO-PEG4-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-116186

m-PEG5-Ms	ADC Linker PROTAC Linkers	Cancer
m-PEG5-Ms is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG5-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W040214

m-PEG4-Amine	ADC Linker PROTAC Linkers	Cancer
m-PEG4-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W008429

m-PEG2-Amine	ADC Linker PROTAC Linkers	Cancer
m-PEG2-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG2-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130571

m-PEG9-Amine	ADC Linker PROTAC Linkers	Cancer
m-PEG9-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG9-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-125541

DBCO-NHCO-PEG4-acid	ADC Linker PROTAC Linkers	Cancer
DBCO-Amide-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-Amide-PEG5-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-117031

m-PEG8-Ms	ADC Linker PROTAC Linkers	Cancer
m-PEG8-Ms is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG8-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-112617

Thalidomide-O-amido-PEG2-C2-NH2 Cereblon Ligand-Linker conjugates 10; E3 Ligase Ligand-Linker conjugates 24	E3 Ligase Ligand-Linker Conjugates	Cancer Inflammation/Immunology
Thalidomide-O-amido-PEG2-C2-NH2 incorporates an E3 ligase ligand and a linker, can be an immunomodulater for the treatment of cancer.

HY-116427

Propargyl-PEG4-thiol	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG4-thiol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-thiol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130372

Propargyl-PEG9-bromide	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG9-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG9-bromide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W040222

m-PEG11-Amine	ADC Linker PROTAC Linkers	Cancer
m-PEG11-Amino is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG11-Amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-130591

Propargyl-PEG4-Br	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG4-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130377

Propargyl-PEG8-bromide	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG8-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-bromide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-132158

MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin	Drug-Linker Conjugates for ADC	Cancer
MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (compound 21a), a camptothecin payload, can be conjugated to a monoclonal antibody (mAb) for the synthesis of camptothecin *antibody-drug conjugate* (ADC)**.

HY-126974

Propargyl-PEG3-NHS ester	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG3-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130388

Propargyl-PEG5-NHS ester	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-145397

(4-NH2)-Exatecan	Topoisomerase	Cancer
(4-NH2)-Exatecan, a topoisomerase inhibitor derivative extracted from patent US20200306243A1, compound A. (4-NH2)-Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs).

HY-126889

Bis-PEG5-NHS ester	ADC Linker PROTAC Linkers	Cancer
Bis-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130825

Bis-PEG13-NHS ester	PROTAC Linkers ADC Linker	Cancer
Bis-PEG13-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG13-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130381

Propargyl-PEG7-NHS ester	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG7-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130827

Bis-PEG21-NHS ester	PROTAC Linkers ADC Linker	Cancer
Bis-PEG21-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG21-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130385

Propargyl-PEG6-NHS ester	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130826

Bis-PEG17-NHS ester	ADC Linker PROTAC Linkers	Cancer
Bis-PEG17-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG17-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130828

Bis-PEG25-NHS ester	PROTAC Linkers ADC Linker	Cancer
Bis-PEG25-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG25-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130376

Propargyl-PEG8-NHS ester	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG8-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-126890

Bis-PEG7-NHS ester	ADC Linker PROTAC Linkers	Cancer
Bis-PEG7-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130824

Bis-PEG10-NHS ester	PROTAC Linkers ADC Linker	Cancer
Bis-PEG10-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG10-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-27787

α-Eleostearic acid cis-Eleostearic acid	Apoptosis Ferroptosis	Cancer Metabolic Disease
α-Eleostearic acid (cis-Eleostearic acid), a conjugated linolenic acid, is an apoptosis inducer. α-Eleostearic acid is also a ferroptosis inducer. α-Eleostearic acid exhibits antioxidant and antitumor activity.

HY-131955

Fmoc-aminooxy-PEG2-NH2
ADC Linker Cancer

Fmoc-aminooxy-PEG2-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-132252

Mal-PEG8-Val-Ala-PABC
ADC Linker Cancer

Mal-PEG8-Val-Ala-PABC is a cleavable Tesirine linker used in the synthesis of Tesirine, a drug-linker conjugate for ADC.

HY-15583

Auristatin F	ADC Cytotoxin Microtubule/Tubulin	Cancer
Auristatin F is a potent cytotoxin in antibo-conjugated drugs and an analogue of MMAF. Auristatin F is a potent microtubule inhibitor and vascular damaging agent (VDA). Auristatin F inhibits cell division by preventing tubulin aggregation.Auristatin F can be used in antibody-drug conjugates (ADC) .

HY-120702

N-Boc-PEG5-bromide	ADC Linker PROTAC Linkers	Cancer
N-Boc-PEG5-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W006445

N-Boc-PEG3-bromide	ADC Linker PROTAC Linkers	Cancer
N-Boc-PEG3-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG3-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130505

N-Boc-PEG7-alcohol	ADC Linker PROTAC Linkers	Cancer
N-Boc-PEG7-alcohol is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG7-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W071584

N-Boc-PEG6-alcohol	ADC Linker PROTAC Linkers	Cancer
N-Boc-PEG6-alcohol is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG6-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W046471

N-Boc-PEG4-bromide	ADC Linker PROTAC Linkers	Cancer
N-Boc-PEG4-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG4-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130503

N-Boc-PEG2-bromide	ADC Linker PROTAC Linkers	Cancer
N-Boc-PEG2-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG2-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W071583

N-Boc-PEG9-alcohol	ADC Linker PROTAC Linkers	Cancer
N-Boc-PEG9-alcohol is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG9-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-145989

Aminobenzenesulfonic auristatin E	Drug-Linker Conjugates for ADC Microtubule/Tubulin	Cancer
Aminobenzenesulfonic auristatin E is a *drug-linker conjugate* for ADC**. Aminobenzenesulfonic auristatin E has potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic.

HY-143209

DSPE-PEG	Liposome	Others
DSPE-PEG is a phospholipids-polymer conjugate that can be used in drug delivery applications. DSPE-PEG is a material for the formulation of nanocarriers for achieving prolonged blood circulation time, improved stability and enhanced encapsulation efficiency.

HY-103608

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl VHL Ligand-Linker conjugates 11; E3 ligase Ligand-Linker conjugates 11	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3-PEG)2-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays.

HY-130449

N-Boc-N-bis(PEG4-OH)	ADC Linker PROTAC Linkers	Cancer
N-Boc-N-bis(PEG4-OH) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-N-bis(PEG4-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-126884

DBCO-NHCO-PEG4-NH-Boc	ADC Linker PROTAC Linkers	Cancer
DBCO-NHCO-PEG4-NH-Boc is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NH-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-145620

Zuvotolimod	ADC Linker	Cancer Inflammation/Immunology
Zuvotolimod is a myeloid cell agonist compound-linker for antibody conjugate. Zuvotolimod can be used in the research of cancer and hepatitis.

HY-115384

Amino-PEG5-C2-acid	ADC Linker PROTAC Linkers	Cancer
Amino-PEG5-C2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG5-C2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-147239

MC-VA-PABC-MMAE	Drug-Linker Conjugates for ADC	Cancer
MC-VA-PABC-MMAE is a *drug-linker conjugate* for ADC**. MC-VA-PABC-MMAE contains the ADCs linker (peptide MC-VA-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162).

HY-145989A

Aminobenzenesulfonic auristatin E TFA	Drug-Linker Conjugates for ADC Microtubule/Tubulin	Cancer
Aminobenzenesulfonic auristatin E TFA is a *drug-linker conjugate* for ADC**. Aminobenzenesulfonic auristatin E TFA has potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic.

HY-D0150

Thiazole Orange	Fluorescent Dye	Others
Thiazole orange is an unsymmetrical cyanine dye which can be conjugated to oligonucleotides (ONs) to create fluorogenic hybridisation probes. Thiazole orange can be used for reticulocyte analysis.

HY-130182

Propargyl-PEG8-NH2	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG8-NH2 (compound 3b) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NH2 is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-117079

N-Boc-N-bis(PEG2-OH)	ADC Linker PROTAC Linkers	Cancer
N-Boc-N-bis(PEG2-OH) is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-N-bis(PEG2-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-121805

DBCO-C6-acid	ADC Linker	Cancer
DBCO-C6-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be used in the synthesis of carmaphycin analogues.

HY-150502

Poly(styrenyl acetal trehalose) pSAT	Biochemical Assay Reagents	Others
Poly(styrenyl acetal trehalose) (pSAT) is composed of trehalose side chains linked to a polystyrene backbone via acetals. Poly(styrenyl acetal trehalose) stabilizes a variety of proteins and enzymes against fluctuations in temperature, and does not trigger the innate immune response. Poly(styrenyl acetal trehalose) can be used in synthesis of protein-polymer conjugates for reduced renal clearance of the biomolecule.

HY-W007324

Maleimide	Others	Cancer
Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes.

HY-132180A

Seco-DUBA	ADC Cytotoxin	Cancer Inflammation/Immunology
Seco-DUBA is a duocarmycin (DUBA) prodrug containing two hydroxyl groups, which can each be used for coupling to an antibody via a linker. Seco-DUBA can be used in the synthesis of antibody-drug conjugates (ADCs).

HY-151559

*Zn-DPA-maytansinoid conjugate* 1**	Checkpoint Kinase (Chk) STAT CXCR CCR	Cancer
Zn-DPA-maytansinoid conjugate 1 is a small molecule-based maytansinoid conjugate targeting immune checkpoint. Zn-DPA-maytansinoid conjugate 1 induces lasting regression of tumor growth and rejuvenates tumor microenvironment (TME) to an “inflamed hot tumor”.

HY-136291

Sulfo-SPDB-DGN462	Drug-Linker Conjugates for ADC	Cancer
Sulfo-SPDB-DGN462 is a *drug-linker conjugate* for ADC*. Sulfo-SPDB-DGN462 consists a toxin DGN462 (HY-101150) conjugated* to the cleavable Sulfo-SPDB linker. DGN462, a potent DNA-alkylating agent, shows anti-tumor activity, such as acute myeloid leukemia (AML).

HY-147286A

Ac-Lys-Val-Cit-PABC-MMAE formic	Drug-Linker Conjugates for ADC	Cancer
Ac-Lys-Val-Cit-PABC-MMAE (formic) is a *drug-linker conjugate* for ADC. Ac-Lys-Val-Cit-PABC-MMAE contains the ADC linker (peptide Ac-Lys-Val-Cit-PABC) and a potent tubulin** polymerization inhibitor Monomethyl auristatin E (HY-15162).

HY-132254

Sacituzumab govitecan IMMU-132	Antibody-Drug Conjugates (ADCs)	Cancer
Sacituzumab govitecan (IMMU-132) is an *antibody-drug conjugate* (ADC) targeting Trop-2** for delivery of SN-38. Sacituzumab govitecan shows anticancer activity.

HY-130690

Propargyl-PEG1-SS-PEG1-C2-Boc	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG1-SS-PEG1-C2-Boc is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG1-SS-PEG1-C2-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-111012

DBCO-(PEG)3-VC-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
DBCO-(PEG)3-VC-PAB-MMAE is a *drug-linker conjugate* for ADC*. DBCO-(PEG)3-VC-PAB-MMAE is made by Monomethyl auristatin E (HY-15162) conjugats* to DBCO-(PEG)3-vc-PAB linker. DBCO-(PEG)3-VC-PAB-MMAE can be used for the research of cancer.

HY-145989S

Aminobenzenesulfonic auristatin E-d8	Drug-Linker Conjugates for ADC Microtubule/Tubulin	Cancer
Aminobenzenesulfonic auristatin E-d₈ is the deuterium labeled Aminobenzenesulfonic auristatin E. Aminobenzenesulfonic auristatin E is a drug-linker conjugate for ADC. Aminobenzenesulfonic auristatin E has potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic[1][2].

HY-P99785

Opucolimab HLX20	PD-1/PD-L1	Cancer
Opucolimab is an anti-PD-L1 recombinant human monoclonal antibody. Opucolimab can be used to synthesis antibody drug conjugates. Opucolimab can be used for the research of advanced solid tumors.

HY-129703B

Thalidomide-PEG2-C2-NH2 hydrochloride Thalidomide-NH-PEG2-C2-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-PEG2-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.

HY-129703

Thalidomide-PEG2-C2-NH2 Thalidomide-NH-PEG2-C2-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-PEG2-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.

HY-W048671

Fmoc-Thr(TBDMS)-OH	Amino Acid Derivatives	Others
Fmoc-Thr(TBDMS)-OH is a Threonine derivative. Fmoc-Thr(TBDMS)-OH can be used for the preparation of sugar ligand-tethered functional nucleic acid conjugates for targeted therapy.

HY-129703A

Thalidomide-PEG2-C2-NH2 TFA Thalidomide-NH-PEG2-C2-NH2 TFA	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.

HY-P99534

Upifitamab rilsodotin XMT-1536	ADC Linker	Cancer
Upifitamab rilsodotin (XMT-1536) is an antibody-drug conjugate targeting NaPi2b. Upifitamab rilsodotin can be used for the research of cancer, including Ovarian cancer.

HY-141898

Biotin-4-aminophenol	Fluorescent Dye	Others
Biotin-4-aminophenol is a biotin-phenol analog. Biotin-4-aminophenol generates free radicals and conjugates to tyrosine residues in proteins more efficiently and selectively than the previously reported BP1.

HY-129938

PROTAC BRD4 degrader for PAC-1	PROTAC-Linker Conjugates for PAC	Cancer
PROTAC BRD4 degrader for PAC-1 (compound 5), a PROTAC-linker Conjugate for PAC, comprises the chimeric BET degrader GNE-987 and disulfide-containing linker.

HY-78961

6-Maleimidohexanoic acid N-hydroxysuccinimide ester EMCS	ADC Linker	Cancer
6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) is a heterobifunctional cross-linking reagent. EMCS is used as a unique and useful reagent for preparation of hapten conjugate and enzyme immunoconjugates.

HY-148128

TAM470	Microtubule/Tubulin ADC Cytotoxin	Cancer
TAM470 is a novel cytolysin, inhibiting tubulin polymerization and microtubule depolymerization. TAM470 can be used in the synthesis of OMTX705 as payload molecule, OMTX705 is a novel FAP-targeting antibody-drug conjugates (ADCs) with antitumor activity.

HY-D1655

BDP 581/591 DBCO	Fluorescent Dye	Others
BDP 581/591 DBCO is a borondipyrromethene dye with a conjugated olefin system (Ex=585 nm, Em=594 nm). BDP 581/591 DBCO can be used as a conventional fluorophore or for the detection of ROS (after oxidation, fluorescence moves to the green part of the spectrum).

HY-148680

CL845-PAB-Ala-Val-C5-MC	STING	Cancer
CL845-PAB-Ala-Val-C5-MC is a conjugatable STING ligand， it is synthesized from the proprietary cyclic dinuleotide HY-148679 CL845. CL845-PAB-Ala-Val-C5-MC can be used for bioconjugation.

HY-148681

CL845-PAB-Ala-Val-PEG4-Azide	STING	Cancer
CL845-PAB-Ala-Val-PEG4-Azide is a conjugatable STING ligand， it is synthesized from the proprietary cyclic dinuleotide HY-148679 CL845. CL845-PAB-Ala-Val-PEG4-Azide can be used for bioconjugation.

HY-133799

Pomalidomide-C7-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-C7-COOH is a synthesized E3 ligase cereblon ligand-linker conjugate. Pomalidomide-C7-COOH is an intermediate for the synthesis of PROTAC BCL-XL degraders.

HY-148245

OH-Glu-Val-Cit-PAB-MMAE	ADC Linker	Cancer
OH-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (OH-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs).

HY-111456

DBCO-NHCO-PEG4-NHS ester	ADC Linker PROTAC Linkers	Cancer
DBCO-NHCO-PEG4-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-114816

N-Butanoyl-L-homoserine lactone C4-HSL; N-Butyryl-L-homoserine lactone	ADC Linker Bacterial	Infection Inflammation/Immunology
N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa.

HY-P99612

Farletuzumab ecteribulin MORAb-202	Antibody-Drug Conjugates (ADCs)	Cancer
Farletuzumab ecteribulin (MORAb-202) is an *antibody-drug conjugate* (ADC)*, consisting of the humanized anti-human folate receptor alpha (FRA) antibody Farletuzumab (HY-P99153) conjugated* via reduced interchain disulfide bonds to Mal-PEG2-Val-Cit-PAB-eribulin. Farletuzumab ecteribulin has a drug-to-antibody ratio of 4.0. Farletuzumab ecteribulin is highly cytotoxic to FRA-positive cells in vitro. Farletuzumab ecteribulin has potent antitumor activity.

HY-100566

SuO-Val-Cit-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
SuO-Val-Cit-PAB-MMAE is a *drug-linker conjugate* for ADC** by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the peptide SuO-Val-Cit-PAB.

HY-145399

Mal-PEG8-amide-Val-Ala-(4-NH2)-Exatecan	Drug-Linker Conjugates for ADC	Cancer
Mal-PEG8-amide-Val-Ala-(4-NH2)-Exatecan is a conjugate used to synthesis ADC. Mal-PEG8-amide-Val-Ala-(4-NH2)-Exatecan comprises topoisomerase inhibitor derivative with a linker for connecting to a ligand unit (extracted from patent US20200306243A1).

HY-148225

Fulvestrant 3-β-D-Glucuronide	Others	Cancer
Fulvestrant 3-β-D-Glucuronide, a metabolite, is glucuronide and sulfate conjugates of Fulvestrant (HY-13636), a pure anti-estrogenic steroid. Fulvestrant 3-β-D-Glucuronide can be used for the research of breast cancer.

HY-145314

TC113	Integrin	Cancer
TC113 is a c(RGDyK)-Based conjugate of Gemcitabine (GEM). TC113 could be internalized by A549 cells through integrin α_vβ₃. TC113 shows potent antiproliferative properties against WM266.4 and A549 cells.

HY-130379

Propargyl-PEG8-acid	ADC Linker PROTAC Linkers Bacterial	Cancer Infection
Propargyl-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The ADCs can be used in bacterial infections caused by Gram-negative bacteria.

HY-130652

Pomalidomide 4'-PEG3-azide	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a linker. Pomalidomide 4'-PEG3-azide can be used for the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3 is a highly efficient PARP1 degrader based on Rucaparib by using the PROTAC approach.

HY-115446A

Lenalidomide-C4-NH2 hydrochloride Cereblon ligand 1 hydrochloride; E3 ligase Ligand-Linker conjugates 32 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Lenalidomide-C4-NH2 hydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C4-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC (Compound 24), which has IC₅₀s of 0.98 nM and 13.7 nM in inhibition of RS4;11 and MOLM-13 acute leukemia cell lines growth, respectively.

HY-130812

Gemcitabine-O-Si(di-iso)-O-Mc	Drug-Linker Conjugates for ADC	Cancer
Gemcitabine-O-Si(di-iso)-O-Mc is a *drug-linker conjugate* for ADC** with potent antitumor activity by using Gemcitabine (a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent; HY-17026), linked via the ADC linker.

HY-126894

Bis-PEG9-acid	PROTAC Linkers ADC Linker	Cancer
Bis-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG9-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-126893

Bis-PEG8-acid	PROTAC Linkers ADC Linker	Cancer
Bis-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-126892

Bis-PEG7-acid	PROTAC Linkers ADC Linker	Cancer
Bis-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130408

m-PEG6-Amine	ADC Linker PROTAC Linkers	Cancer
m-PEG6-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG6-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W018174

m-PEG3-Amine	ADC Linker PROTAC Linkers	Cancer
m-PEG3-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-P99230

Pinatuzumab	Integrin CD22	Cancer
Pinatuzumab is a CD22 monoclonal antibody. Pinatuzumab targets the cell-surface antigen CD22. Pinatuzumab can be used for synthesis of antibody drug conjugates (ADCs) to research several diseases including non-Hodgkin lymphoma (NHL).

HY-118808

Propargyl-PEG2-NHBoc	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG2-NHBoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-140310

TCO-PEG4-DBCO	ADC Linker PROTAC Linkers	Cancer
TCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130410

Bis-PEG6-NHS ester	ADC Linker PROTAC Linkers	Cancer
Bis-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130387

Propargyl-PEG4-Tos	PROTAC Linkers ADC Linker	Cancer
Propargyl-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-126976

Propargyl-PEG5-amine	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG5-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-124386

DBCO-NHCO-PEG4-amine	ADC Linker PROTAC Linkers	Cancer
DBCO-NHCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE (HY-15162) and antibody (e.g., DBCO-VCpAB−MMAE and DBCO-TRX−MMAE with EC₅₀s of 280 nM and 22 nM in SKBR3 cells, respectively).

HY-W051634

Propargyl-PEG2-amine	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG2-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-130654

(S,R,S)-AHPC-C2-PEG4-N3 VH032-C2-PEG4-N3	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C2-PEG4-N3 (VH032-C2-PEG4-N3) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. (S,R,S)-AHPC-C2-PEG4-N3 can be used in the synthesis of vRucaparib-TP4 (HY-130647). vRucaparib-TP4 a highly potent PARP1 degrader with a half-maximal degrading concentration (DC₅₀) of 82 nM.

HY-126885

DBCO-PEG5-NHS ester	ADC Linker PROTAC Linkers	Cancer
DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-115400

1V209 TLR7 agonist T7	Toll-like Receptor (TLR)	Cancer
1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects. 1V209 can be conjugated with various polysaccharides to improve its water solubility, and enhance its efficacy, and maintain low toxicity.

HY-P99233

Camidanlumab HuMax-TAC	Interleukin Related	Cancer
Camidanlumab (HuMax-TAC) is a CD25 monoclonal antibody. Camidanlumab targets the cell-surface antigen CD25, which is over-expressed on a variety of hematological tumors and shows limited expression on normal tissues. Camidanlumab can be used for synthesis of antibody drug conjugates (ADCs) to research several diseases including lymphoma and leukemia.

HY-P99107

Brentuximab vedotin	Antibody-Drug Conjugates (ADCs) Apoptosis TNF Receptor	Cancer
Brentuximab vedotin (cAC10-vcMMAE) is an antibody-drug conjugate (ADC) comprising an anti-CD30 antibody and the cytotoxic agent Monomethyl auristatin E (MMAE). Brentuximab vedotin inhibits CD30-positive cells with an IC₅₀ of 2.5 ng/mL. Brentuximab vedotin can be used for the research of relapsed and refractory Hodgkin lymphoma.

HY-145951

Amidate-VC-PAB-MMAF	Drug-Linker Conjugates for ADC	Cancer
Amidate-VC-PAB-MMAF consists a cleavable ADC linker (Amidate-VC-PAB) and a potent tubulin polymerization inhibitor (MMAF). Amidate-VC-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs). Amidate-VC-PAB-MMAF reduces off-target cytotoxicity of ADCs.

HY-130435

DBCO-PEG4-amine	ADC Linker PROTAC Linkers	Cancer
DBCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker).

HY-152121

Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal	Glucocorticoid Receptor Drug-Linker Conjugates for ADC	Infection Inflammation/Immunology
Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal is a glucocorticoid receptor agonist. Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal can be used in *anti-CD40 antibody drug conjugate* (ADC)**. Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal can be used for the research of inflammation and immune regulation.

HY-130816

(S,R,S)-AHPC-O-Ph-PEG1-NH2 VH032-O-Ph-PEG1-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-O-Ph-PEG1-NH2 (VH032-O-Ph-PEG1-NH2) is E3 ligase ligand-linker conjugate and incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-O-Ph-PEG1-NH2 is used in PROTAC EED degrader-1 (HY-130614). PROTAC EED degrader-1 is a PROTAC targeting EED with a pK_D of 9.02.

HY-138298A

Trastuzumab deruxtecan DS-8201; DS-8201a	Antibody-Drug Conjugates (ADCs) EGFR	Cancer
Trastuzumab deruxtecan (DS-8201a) is an anti-*human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate* (ADC)**. Trastuzumab deruxtecan is composed of a humanized anti-HER2 antibody, an enzymatically cleavable peptide-linker, and a topoisomerase I inhibitor. Trastuzumab deruxtecan can be used for the research of HER2-positive breast cancer and gastric cancer.

HY-126781

Fozivudine tidoxil BM-211290	HIV DNA/RNA Synthesis	Infection
Fozivudine tidoxil (BM-211290) is an orally active thioether lipid-zidovudine (ZDV) conjugate with anti-HIV activity. Fozivudine tidoxil, a member of the NRTI family of drug, is incorporated into the newly synthesized strand of DNA during intracellular viral replication and irreversibly binds viral RT which disrupts viral reverse-transcription.

HY-147281

BAY 1135626	ADC Cytotoxin Others	Cancer
BAY 1135626 is used to synthesize BAY 1129980, and use to anti-tumor research. BAY 1129980 is a Auristatin-based anti-C4.4A (LYPD3) antibody–drug conjugate (ADC), is used to non–small cell lung cancer (NSCLC) research.

HY-138298

Trastuzumab deruxtecan (solution) DS-8201 (solution); DS-8201a (solution)	Antibody-Drug Conjugates (ADCs) EGFR	Cancer
Trastuzumab deruxtecan (DS-8201a) (solution) is an anti-*human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate* (ADC)**. Trastuzumab deruxtecan (solution) is composed of a humanized anti-HER2 antibody, an enzymatically cleavable peptide-linker, and a topoisomerase I inhibitor. Trastuzumab deruxtecan (solution) can be used for the research of HER2-positive breast cancer and gastric cancer.

HY-W074648

Antibacterial agent 18	Bacterial	Infection
Antibacterial agent 18 is a multi-arm AIE molecule extracted from patent CN110123801A, compound 23. Antibacterial agent 18 can be used for resisting Gram-positive and Gram-negative bacteria. Antibacterial agent 18 can be conjugated in the cell wall of rigid arm configuration insertion bacterium, and block cell wall turns sugar and turns peptide process, to inhibit or kill bacterium.

HY-148101

BT5528	Ephrin Receptor	Cancer
BT5528 is a bicyclic peptide toxin conjugate, an EphA2 activator. BT5528, made up of a bicyclic peptide and Auristatin E (HY-15582), is derivated from BCY6099. BT5528 shows potent anti-tumor activity without bleeding or coagulation toxicity in rats model.

HY-148346

STING agonist-20-Ala-amide-PEG2-C2-NH2	Drug-Linker Conjugates for ADC STING	Cancer
STING agonist-20-Ala-amide-PEG2-C2-NH2 is an active scaffold comprising a stimulator of interferon genes (STING). STING agonist-20-Ala-amide-PEG2-C2-NH2 can be used to synthesize immune-stimulating antibody conjugate (ISAC). STING agonist-20-Ala-amide-PEG2-C2-NH2 can be used for the research of cancer.

HY-146540

GEM-5	HIF/HIF Prolyl-Hydroxylase Apoptosis MDM-2/p53	Cancer
GEM-5 is a gemcitabine-based conjugate containing a HIF-1α inhibitor (YC-1) (IC₅₀=30 nM). GEM-5 can significantly down-regulate the expression of HIF-1α and up-regulate the expression of tumor suppressor p53. GEM-5 induces the apoptosis of A2780 cells and inhibits tumor growth.

HY-148346A

STING agonist-20-Ala-amide-PEG2-C2-NH2 TFA	Drug-Linker Conjugates for ADC STING	Cancer
STING agonist-20-Ala-amide-PEG2-C2-NH2 (Compound 30b) TFA is an active scaffold comprising a stimulator of interferon genes (STING). STING agonist-20-Ala-amide-PEG2-C2-NH2 TFA can be used to synthesize immune-stimulating antibody conjugate (ISAC). STING agonist-20-Ala-amide-PEG2-C2-NH2 TFA can be used for the research of cancer.

HY-151792

Pomalidomid-C6-PEG3-butyl-N3	PROTACs	Cancer Metabolic Disease Inflammation/Immunology
Pomalidomid-C6-PEG3-butyl-N3 is a click chemistry reagent containing an azide group. Pomalidomid-C6-PEG3-butyl-N3 also is a crosslinker-E3 ligase ligand conjugate, which be used in click reactive protein degrader building block for PROTAC research. Pomalidomid-C6-PEG3-butyl-N3 also can be used in the template for synthesis of targeted protein degrader.

HY-113293A

Estrone sulfate potassium
Endogenous Metabolite Endocrinology Cancer

Estrone sulfate potassium is a natural endogenous steroid and is an estrogen ester and conjugate.

HY-135660

MMAE-SMCC	Drug-Linker Conjugates for ADC	Cancer
MMAE-SMCC is a drug-linker conjugate for ADC. MMAE-SMCC is composed of a potent mitotic and a tubulin inhibitor MMAE and a linker SMCC to make antibody drug conjugate.

HY-128926

SPP
ADC Linker Cancer

SPP is a cleavable disulfide linker, can be used to form cytotoxic compound- linker conjugate.
HY-130099

Ald-Ph-amido-PEG2
ADC Linker Cancer

Ald-Ph-amido-PEG2 is a noncleavable ADC linker for antibody-drug conjugate.

HY-132943

*BRD4 ligand-Linker Conjugate* 1**	Target Protein Ligand-Linker Conjugates	Cancer
BRD4 ligand-Linker Conjugate 1 is a target protein ligand-linker conjugate that can be used in the synthesis of PROTACs.

HY-78738

MC-Val-Cit-PAB
ADC Linker Cancer

MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate.
HY-141664

PPA
ADC Linker Cancer

PPA is an ADC linker (US20060073528A1). PPA can be used for making antibody-drug conjugate.

HY-W072147

Fmoc-Ser-OMe Fmoc-L-Ser-OMe	Amino Acid Derivatives	Others
Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected with a 9-fluorenylmethyloxycarbonyl (Fmoc) group. Fmoc-Ser-OMe involves in chlorophyll–amino acid conjugates synthesis, and acts as a chromo/fluorophores modified protein and emits visible to near-infrared lights efficiently. Fmoc-Ser-OMe glycosylates and produces small mucin-related Olinked glycopeptides, as an alcohol acceptor.

HY-129356A

(S)-Seco-Duocarmycin SA	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
(S)-Seco-Duocarmycin SA is a DNA alkylator, cytotoxic to cancer cells, and acts as a ADC cytotoxin for antibody-drug conjugates.

HY-148202

Influenza antiviral conjugate-1
HIV Infection

Influenza antiviral conjugate-1 (INT-2) is a HIV inhibitor, shows potent cell fusion inhibition.

HY-15740

Mc-MMAD	Microtubule/Tubulin Drug-Linker Conjugates for ADC	Cancer
Mc-MMAD is a protective group (maleimidocaproyl)-conjugated MMAD. MMAD is a potent tubulin inhibitor. Mc-MMAD is a drug-linker conjugate for ADC.

HY-147164

MC-Gly-Gly-Phe-Gly-PAB-PNP
ADC Linker Cancer

MC-Gly-Gly-Phe-Gly-PAB-PNP is a linker for synthesis anti-human EGFR antibody drug conjugate.
HY-151740

4-Pentynoyl-Val-Ala-PAB-PNP
ADC Linker Others

4-Pentynoyl-Val-Ala-PAB-PNP is a cleavable ADC linker, that has been used to synthesis cryptophycin conjugates.

HY-P99360

Enapotamab Anti-AXL/UFO Reference Antibody (enapotamab)	TAM Receptor	Cancer
Enapotamab is an anti-AXL/UFO reference antibody. Enapotamab can be used to synthesis Bcl-xl inhibitor antibody-drug conjugates.

HY-145736A

β-Glucuronide-dPBD-PEG5-NH2 TFA	Drug-Linker Conjugates for ADC Apoptosis	Cancer
β-Glucuronide-dPBD-PEG5-NH2 TFA is the β-glucuronide-linked pyrrolobenzodiazepine dimer, which binds to the prenylated antibody for synthesis of antibody-drug conjugate (ADC) cIRCR201-dPBD.β-glucuronide-linkage as a cleavable linker. β-Glucuronide-dPBD-PEG5-NH2 TFA, as a prodrug of cIRCR201-dPBD, reduces side effects. β-Glucuronide-dPBD-PEG5-NH2 TFA can induce apoptosis and arrest cell cycle. β-Glucuronide-dPBD-PEG5-NH2 TFA has antitumor activity.

HY-145736

β-Glucuronide-dPBD-PEG5-NH2	Drug-Linker Conjugates for ADC Apoptosis	Cancer
β-Glucuronide-dPBD-PEG5-NH2 is the β-glucuronide-linked pyrrolobenzodiazepine dimer, which binds to the prenylated antibody for synthesis of antibody-drug conjugate (ADC) cIRCR201-dPBD. β-glucuronide-linkage as a cleavable linker. β-Glucuronide-dPBD-PEG5-NH2, as a prodrug of cIRCR201-dPBD, reduces side effects. β-Glucuronide-dPBD-PEG5-NH2 can induce apoptosis and arrest cell cycle. β-Glucuronide-dPBD-PEG5-NH2 has antitumor activity.

HY-141793

ATRA-biotin Biotin-ATRA-conjugate	RAR/RXR PPAR Endogenous Metabolite Autophagy	Cancer
ATRA-biotin (Biotin-ATRA-conjugate) is a biotin-conjugated ATRA. ATRA-biotin can be used to track ATRA in cells or a given tissue.

HY-136287

DBM-MMAF
Drug-Linker Conjugates for ADC Cancer

DBM-MMAF is a drug-linker conjugate composed of a potent antitubulin agent MMAF and a linker DBM to make antibody drug conjugate (ADC).
HY-151667

Biotin-C5-Azide
DecarboxyBiotin-N3
Fluorescent Dye Others

Biotin-C5-Azide (DecarboxyBiotin-N3) is a biotin reagent and can be used to prepare biotinylated conjugates.

HY-148231

Dideoxy-amanitin	DNA/RNA Synthesis ADC Cytotoxin	Cancer
Dideoxy-amanitin (compound 2), an α-Amanitin (HY-19610) derivative, is a potent and selective RNA polymerase II allosteric inhibitor with an IC₅₀ value of 74.2 nM.

HY-133231

Bis-PEG10-acid
PROTAC Linkers Cancer

Bis-PEG10-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-15741

Mc-MMAE Maleimidocaproyl-monomethylauristatin E	Microtubule/Tubulin Drug-Linker Conjugates for ADC	Cancer
Mc-MMAE is a protective group (maleimidocaproyl)-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Mc-MMAE is a drug-linker conjugate for ADC.

HY-148459

ATAC21	Drug-Linker Conjugates for ADC	Cancer
ATAC21, a linker-immune-stimulatory compound that can be formed by conjugating a noncleavable maleimide-PEG4 linker containing a succinimide group with an immune- stimulatory compound. ATAC21 can be combined with SBT-040 (anti-CD40 antibody) to form a conjugate.

HY-151714

Biotin-MeTz	ADC Linker	Others
Biotin-MeTz shiyi is a click chemistry reagent with a terminal methyltetrazine group. Biotin-MeTz shiyi, as a biotin derivative, can be used for the preparation of biotinylated conjugates.

HY-D1710

Anti-α-Tubulin Antibody, AF555 conjugate	Microtubule/Tubulin	Others
Anti-α-Tubulin Antibody, AF555 conjugate is a conjugate of mouse anti-α-tubulin monoclonal antibody and the red fluorescent dye Alexa Fluor 555. Anti-α-Tubulin Antibody, AF555 conjugate can be used for the detection of tubulin (Ex/Em: 554/567 nm).

HY-126690

DBCO-(PEG2-VC-PAB-MMAE)2	Drug-Linker Conjugates for ADC	Cancer
DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.

HY-128960

DBA-DM4
Drug-Linker Conjugates for ADC Cancer

DBA-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM1 and a linker SPDP to make antibody drug conjugate (ADC).

HY-136286

MC-DM1	Drug-Linker Conjugates for ADC	Cancer
MC-DM1 is a drug-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker MC to make antibody drug conjugate (ADC).

HY-131157

Lys(MMT)-PAB-oxydiacetamide-PEG8-N3	ADC Linker	Cancer
Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a cleavable *antibody drug conjugate* linker** used in the synthesis of antibody-drug conjugates (ADCs).

HY-139956

Mal-amido-PEG9-Val-Ala-PAB-SG3200
ADC Linker Cancer

Mal-amido-PEG9-Val-Ala-PAB-SG3200 is a cleavable ADC linker conjugate used in the synthesis of antibody-drug conjugates (ADCs).
HY-144830

6BrCaQ
HSP Cancer

6BrCaQ is a potent mitochondrial heat shock protein TRAP1 inhibitor, with antiproliferative activity. 6BrCaQ can be used in the synthesis of 6BrCaQ-TPP conjugates.

HY-114306

EC0489	Antifolate	Cancer
EC0489, a conjugate of folic acid and desacetyl vinblastine hydrazide, is a high-affinity ligand for the folate receptor (FR). Refractory or metastatic Tumor. Small molecule-drug conjugate (SMDC).

HY-129526

Mal-PEG3-NHS ester
ADC Linker Cancer

Mal-PEG3-NHS ester is a noncleavable ADC linker containing a Maleimide group. Mal-PEG3-NHS ester is used for making antibody-drug conjugate.

HY-126493

DM4-SPDP	Drug-Linker Conjugates for ADC Microtubule/Tubulin	Cancer
DM4-SPDP is a drug-linker conjugate composed of a potent antitubulin agent DM4 and a linker SMCC to make antibody drug conjugate. SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.

HY-128871

VCP-Eribulin	Drug-Linker Conjugates for ADC	Cancer
VCP-Eribulin consists the ADCs linker (VCP) and Eribulin. Eribulin is a mechanistically unique microtubule inhibitor for cancer. VCP-Eribulin is an Eribulin-based drug for antibody conjugates.

HY-136290

Mc-Dexamethasone	Drug-Linker Conjugates for ADC	Cancer
Mc-Dexamethasone is a *drug-linker conjugate* for ADC*. Mc-Dexamethasone is made toxin Dexamethasone (HY-14648) conjugated* to the non-cleavable MC linker. Dexamethasone is a glucocorticoid receptor agonist.

HY-147363

DIBAC-GGFG-NH2CH2-Dxd
Others Others

DIBAC-GGFG-NH2CH2-Dxd (compound LP4), a Camptothecin (HY-16560) derivative, is a linker-payload of protein-drug conjugates.
HY-15902

ABTS diammonium salt
AzBTS-(NH4)2
Fluorescent Dye Others

ABTS diammonium salt is a substrate for horseradish peroxidase (HRP) conjugate.
HY-113162

Bovinic acid
Endogenous Metabolite Metabolic Disease

Bovinic acid is a conjugated linoleic acid with anticarcinogenic and anti-atherogenic activities.

HY-128954

Sulfo-PDBA-DM4	Drug-Linker Conjugates for ADC	Cancer Inflammation/Immunology
Sulfo-PDBA-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Sulfo-PDBA to make antibody drug conjugate (ADC). Sulfo-PDBA is a gluthatione cleavable linker.

HY-133571A

Aminohexylgeldanamycin hydrochloride AHGDM hydrochloride	HSP ADC Cytotoxin	Cancer
Aminohexylgeldanamycin (AHGDM) hydrochloride, a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin hydrochloride shows antiangiogenic and antitumor activities.

HY-147204

Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE	Others	Cancer
Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE (compound S6) is a potent anticancer agent, which can be specific activated by tumor microenvironment. Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE can suppress tumor growth in mice (extracted from patent CN104147612A).

HY-133571

Aminohexylgeldanamycin AHGDM	HSP ADC Cytotoxin	Cancer
Aminohexylgeldanamycin (AHGDM), a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin shows antiangiogenic and antitumor activities.

HY-148067

*XMT-1519 conjugate-1*	ADC Linker	Cancer
ΧΜΤ-1519 conjugate-1 (compound 31) is a linker for the HER-2 monoclonal antibody XMT-1519, which can be used to synthesize ADC and increase anti-tumor activity.

HY-101070

SMCC-DM1 DM1-SMCC	Drug-Linker Conjugates for ADC	Cancer
SMCC-DM1 (DM1-SMCC) is a drug-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody drug conjugate (ADC).

HY-P4091

LSD
Fluorescent Dye Cancer

LSD is a conjugate with phthalocyanine dye for photoimmunotherapy research.
HY-147325

bisSP1
ADC Linker Others

bisSP1 is an antibody drug conjugates linker.

HY-114325

AcLysValCit-PABC-DMAE-SW-163D	Drug-Linker Conjugates for ADC	Cancer
AcLysValCit-PABC-DMAE-SW-163D is a *drug-linker conjugates* for ADC** which consists of a natural bis-intercalator, SW-163D, conjugated via an AcLysValCitPABC-DMAE linker.

HY-136260

DBCO-PEG4-Ahx-DM1	Drug-Linker Conjugates for ADC	Cancer
DBCO-PEG4-Ahx-DM1 is a drug-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody drug conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.

HY-141596

Lys-Nε-SPDB-DM4	Drug-Linker Conjugates for ADC	Cancer
Lys-Nε-SPDB-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Lys-Nε-SPDB to make antibody drug conjugate (ADC).

HY-N1424

Glycoursodeoxycholic acid Ursodeoxycholylglycine	Endogenous Metabolite	Neurological Disease
Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.

HY-129365

SNPB
ADC Linker Cancer

SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC).
HY-101604

Atrimustine
Bestrabucil; KM2210
Others Cancer

Atrimustine is a conjugate of chlorambucil and β-estradiol benzoate with the antitumor activity.

HY-136288

Azide-PEG4-VC-PAB-Doxorubicin	Drug-Linker Conjugates for ADC	Cancer
Azide-PEG4-VC-PAB-Doxorubicin is a drug-linker conjugate composed of a cytotoxic anthracycline antibiotic Doxorubicin and a linker Azide-PEG4-VC-PAB to make antibody drug conjugate (ADC).

HY-145960

MC-Val-Cit-PAB-Amide-TLR7 agonist 4	EGFR Toll-like Receptor (TLR)	Inflammation/Immunology
MC-Val-Cit-PAB-Amide-TLR7 agonist 4 (example 15) is a HER2-TLR7 and HER2-TLR8 immune agonist conjugate.

HY-112942

CMP-Sialic acid CMP-Neu5Ac	Endogenous Metabolite	Metabolic Disease
CMP-Sialic acid (CMP-Neu5Ac) is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid provides a substrate for Golgi sialyltransferases. CMP-Sialic acid is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates.

HY-18569S

3-Indoleacetic acid-d5 Indole-3-acetic acid-d₅; 3-IAA-d₅	Isotope-Labeled Compounds Endogenous Metabolite	Others
3-Indoleacetic acid-d₅ is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-d₅ can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates[1].

HY-112942A

CMP-Sialic acid sodium salt CMP-Neu5Ac sodium salt	Endogenous Metabolite	Metabolic Disease
CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium salt is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates.

HY-19792

Mertansine DM1; Maytansinoid DM1	Microtubule/Tubulin ADC Cytotoxin	Cancer
Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC).

HY-112100

PAC	Estrogen Receptor/ERR PROTAC-Linker Conjugates for PAC	Cancer
PAC, consists the ADCs linker and PROTACs, conjugated to an antibody. PAC extracts from patent WO2017201449A1, compound LP2. PAC conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).

HY-148326

Glu(OtBu)-Val-Cit-PAB-OH	ADC Linker	Others
Glu(OtBu)-Val-Cit-PAB-OH (compound L5-1c) is an non-cleavable ADC linker. Glu(OtBu)-Val-Cit-PAB-OH has been used to synthesis protein-tubulysin conjugates.

HY-15750

Cys-mcMMAD
Microtubule/Tubulin Drug-Linker Conjugates for ADC Cancer

Cys-mcMMAD is a drug-linker conjugate for ADC. MMAD is a potent tubulin inhibitor.
HY-42146

BMPS
ADC Linker Cancer

BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129376

Sulfo-SNPB
ADC Linker Cancer

Sulfo-SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC).

HY-15581

MMAD Demethyldolastatin 10; Monomethylauristatin D; Monomethyl Dolastatin 10	Microtubule/Tubulin ADC Cytotoxin	Cancer
MMAD is a potent tubulin inhibitor, is a toxin payload in antibody drug conjugates (ADCs).

HY-19839

Ansamitocin P 3' Antibiotic C 15003P3'; Maytansinol butyrate	ADC Cytotoxin Microtubule/Tubulin	Cancer
Ansamitocin P 3' exhibits antitumour activity, is an antibody drug conjugate cytotoxin.

HY-126519

PDdEC-NB
ADC Linker Cancer

PDdEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).

HY-15938

5-FAM SE	Fluorescent Dye	Others
5-FAM SE is a single isomer, is a fluorescent labeling reagent used for labeling peptides, proteins and nucleotides. 5-FAM SE can react with amines and can yield stable amine conjugates. Storage: protect from light.

HY-126686

Mal-Phe-C4-VC-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
Mal-Phe-C4-VC-PAB-MMAE is made by MMAE conjugated to Mal-Phe-C4-VC-PAB linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.

HY-44148

*FAK ligand-Linker Conjugate* 1**	Target Protein Ligand-Linker Conjugates	Cancer
FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). FAK ligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation.

HY-129366

PDB-Pfp
ADC Linker Cancer

PDB-Pfp is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-144554

Aminooxy CatB-LXR
Drug-Linker Conjugates for ADC Cancer

Aminooxy CatB-LXR (compound 10) is a drug-linker conjugates for ADC.
HY-129375

SNPB-sulfo-Me
ADC Linker Cancer

SNPB-sulfo-Me is a cleavable linker that is used for making antibody-drug conjugate (ADC).
HY-44235

MC-Gly-Gly-Phe
ADC Linker Cancer

MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).
HY-129373

SPDMV-sulfo
ADC Linker Cancer

SPDMV-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).
HY-139591

Ugodotin
Drug-Linker Conjugates for ADC Cancer

Ugodotin (Compound G-13) is a drug-linker conjugate for ADC.
HY-126667

SC-Val-Cit-PAB
ADC Linker Cancer

SC-Val-Cit-PAB is a cleavable ADC linker for antibody-drug conjugates (ADCs).

HY-152916

mp-dLAE-PABC-MMAE	Drug-Linker Conjugates for ADC	Cancer
mp-dLAE-PABC-MMAE is a drug-linker conjugate for ADC. mp-dLAE-PABC-MMAE contains a potent tubulin inhibitor Monomethyl auristatin E (HY-15162). mp-dLAE-PABC-MMAE can be used to synthesis antibody-drug conjugates (ADCs).

HY-15578

McMMAF Maleimidocaproyl monomethylauristatin F	Drug-Linker Conjugates for ADC	Cancer
McMMAF is a protective group (maleimidocaproyl)-conjugated MMAF, which is a potent tubulin polymerization inhibitor. McMMAF can be used as a drug-linker for *antibody-drug conjugates* (ADC)**. McMMAF is uncleavable, and must be internalized and degraded within a cell, releasing cysteine-McMMAF as the active drug.

HY-148556

Thalidomide-O-C6-azide	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C6-azide is a synthesized E3 ligase ligand-linker conjugate (E3 Ligase Ligand-Linker Conjugates) that incorporates the Thalidomide (Thalidomide (HY-14658)) based cereblon ligand and a linker used in PROTAC technology.

HY-133484B

Thalidomide-PEG2-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-PEG2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate (E3 Ligase Ligand-Linker Conjugates) that incorporates the Thalidomide (Thalidomide (HY-14658)) based cereblon ligand and a linker used in PROTAC technology.

HY-126498

PDEC-NB
ADC Linker Cancer

PDEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).
HY-112114

DTPA-DAB2
Others Others

DAB2-DTPA is a conjugate of DTPA with two DAB used in the photooxidation experiments.
HY-129369

SPDMB
ADC Linker Cancer

SPDMB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).
HY-12448

SPDB
ADC Linker Cancer

SPDB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).

HY-113427

trans-Vaccenic acid	Endogenous Metabolite	Others
trans-Vaccenic acid is a precursor for the synthesis of saturated fatty acid in the rumen and of conjugated linoleic acid (CLA) at the tissue level.

HY-129368

SPDMV
ADC Linker Cancer

SPDMV is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).
HY-126530

PPC-NB
ADC Linker Cancer Cardiovascular Disease

PPC-NB is a glutathione cleavable linker used for the antibody-drug conjugate (ADC).

HY-133540

Maleimide-DOTA Maleimido-mono-amide-DOTA	ADC Linker	Cancer Inflammation/Immunology
Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-148399

Mal-VC-PAB-PNP-CDN-A
Drug-Linker Conjugates for ADC Cancer

Mal-VC-PAB-PNP-CDN-A is a drug-linker conjugate for ADC.
HY-122141

Glycohyocholic acid
GHCA
Endogenous Metabolite Metabolic Disease

Glycohyocholic acid(GHCA) is a glycine-conjugated form of the primary bile acid hyocholic acid.
HY-129370

SPDB-sulfo
ADC Linker Cancer

SPDB-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) .
HY-128927

Mc-Leu-Gly-Arg
ADC Linker Cancer

Mc-Leu-Gly-Arg is a cleavable ether linker for antibody-drug conjugates (ADC) design.

HY-43869

Vipivotide tetraxetan Ligand-Linker Conjugate PSMA-617 Ligand-Linker Conjugate	ADC Linker	Cancer
Vipivotide tetraxetan Ligand-Linker Conjugate (PSMA-617 Ligand-Linker Conjugate) is composed of a linker and Glutamate-urea-Lysine, can be used to synthesize Vipivotide tetraxetan (PSMA-617). Glutamate-urea-Lysine is is the selective pharmacophore to bind to prostate specific membrane antigen (PSMA).

HY-P9985

Disitamab vedotin RC48	Antibody-Drug Conjugates (ADCs) EGFR	Cancer
Disitamab vedotin (RC48) is an antibody-drug conjugate (ADC) comprising a monoclonal antibody against human epidermal growth factor receptor 2 (HER2) conjugated via a cleavable linker to the cytotoxic agent Monomethyl auristatin E (MMAE). Disitamab vedotin enhances antitumor immunity.

HY-126350

CL2-SN-38	Drug-Linker Conjugates for ADC	Cancer
CL2-SN-38 is a cleavable linker-based Drug-Linker conjugate, it can conjugate with the anti-Trop-2-humanized antibody hRS7. CL2-SN-38 can be used for the reasearch of cancer.

HY-151791

(S,R,S)-AHPC-C6-PEG3-butyl-N3	ADC Linker	Others
(S,R,S)-AHPC-C6-PEG3-butyl-N3 is a click chemistry reagent containing an azide group. (S,R,S)-AHPC-C6-PEG3-butyl-N3 serves as crosslinker-E3 ligase ligand conjugate, Click reactive protein degrader building block for PROTAC research, Template for synthesis of targeted protein degrader, VH032 conjugate.

HY-P99657

Iladatuzumab vedotin DCDS-0780A	Antibody-Drug Conjugates (ADCs)	Cancer
Iladatuzumab vedotin (DCDS-0780A) is an *antibody–drug conjugate* (ADC)** containing humanized IgG1 anti-human CD79B monoclonal antibody (MCDS0593A; HY-P99656) conjugated to MMAE via a protease labile linker. Iladatuzumab vedotin uses novel THIOMAB technology (TDC) to consistently conjugate two MMAE molecules per antibody using engineered cysteine residues. Iladatuzumab vedotin has the potential for B-cell non-Hodgkin lymphoma (B-NHL) research.

HY-78931

Boc-Dap-NE
ADC Linker Cancer

Boc-Dap-NE, a dipeptide, is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136095

Tetrazine-biotin
ADC Linker Cancer

Tetrazine-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-150043A

MDTF
ADC Linker Cancer

MDTF is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130111

DMAC-SPP
ADC Linker Cancer

DMAC-SPP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-44246

MC-Gly-Gly-Phe-Gly
ADC Linker Cancer

MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
HY-140014

Val-Cit
ADC Linker Cancer

Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-124422

Pentacosanoic acid
Endogenous Metabolite Metabolic Disease

Pentacosanoic acid is a 25-carbon long-chain saturated fatty acid. Pentacosanoic is a conjugate acid of a pentacosanoate.
HY-144006

14:0 PEG-PE
Liposome Others

14:0 PEG-PE is a PEG-phospholipid conjugate to prepare nanostructured lipid carrier.
HY-139887

Antibacterial agent 63
Bacterial Infection

Antibacterial agent 63, a conjugate of aztreonam to a siderophore mimetic, shows activity against gram-negative bacteria.
HY-101151

sulfo-SPDB
ADC Linker Cancer

sulfo-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-128970

Mp-polymer ester
Drug-Linker Conjugates for ADC Cancer

Mp-polymer ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126349

DTSSP Crosslinker
ADC Linker Cancer

DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140098

Boc-Cystamine
ADC Linker Cancer

Boc-Cystamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129353

Boc-Phe-(Alloc)Lys-PAB-PNP
ADC Linker Cancer

Boc-Phe-(Alloc)Lys-PAB-PNP is a used as a cleavable linker for antibody-drug conjugates (ADC).
HY-126496

PEG4-SPDP
ADC Linker Cancer

PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).
HY-129367

NO2-SPP
ADC Linker Cancer

NO2-SPP is a cleavable linker that is used for making antibody-drug conjugate (ADC).
HY-118759

DSP Crosslinker
ADC Linker Inflammation/Immunology

DSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs).
HY-132915

Anti gram-positive/negative bacteria agent 1
Bacterial Infection

Anti gram-positive/negative bacteria agent 1 is an antibiotic conjugate with an artificial MECAM-based siderophore.
HY-133550

DMAC-SPDB
ADC Linker Cancer

DMAC-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-79584

Propargyl-Tos
ADC Linker Cancer

Propargyl-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-N8252

Xanthoquinodin A1
Antibiotic Infection

Xanthoquinodin A1 is an anticoccidial antibiotic having a new xanthone-anthraquinone conjugate system.
HY-126405

SMPT
ADC Linker Cancer

SMPT is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129352

Cbz-Phe-(Alloc)Lys-PAB-PNP
ADC Linker Cancer

Cbz-Phe-(Alloc)Lys-PAB-PNP is an cleavable linker for antibody-drug conjugates (ADC) design.
HY-133542

Dimethylamine-SPDB
ADC Linker Cancer

Dimethylamine-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-144000

DSPE-PEG-PDP
Liposome Others

DSPE-PEG-PDP is a phospholipid PEG conjugate that can be used in drug delivery applications.
HY-139441

DM21
Drug-Linker Conjugates for ADC Cancer

DM21 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126531

DMAC-PDB
ADC Linker Cancer

DMAC-PDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141593

Modified MMAF-C5-COOH
Drug-Linker Conjugates for ADC Cancer

Modified MMAF-C5-COOH is a drug-linker conjugate for ADC.
HY-136104

Methyltetrazine-Maleimide
ADC Linker Cancer

Methyltetrazine-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-P99528

Vandortuzumab vedotin
DSTP 3086S; RG 7450; MSTP2109A
ADC Linker Cancer

Vandortuzumab vedotin (DSTP 3086S) is an antibody-drug-conjugate to target prostate cancer.

HY-W071006

PPC-NHS ester 2,5-Dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate	ADC Linker	Cancer
PPC-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133543

SPDP-sulfo
ADC Linker Cancer

SPDP-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-20560

(Ac)Phe-Lys(Alloc)-PABC-PNP
ADC Linker Cancer

(Ac)Phe-Lys(Alloc)-PABC-PNP is an useful cleavable chemical linker in antibody drug conjugates.
HY-114697

DSG Crosslinker
ADC Linker Inflammation/Immunology

DSG Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-132604

Fazirsiran ARO-AAT	Small Interfering RNA (siRNA)	Metabolic Disease
Fazirsiran (ARO-AAT) is a second-generation RNAi drug. Fazirsiran consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively degrade AAT mRNA by RNAi and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes.

HY-147271

Mal-PEG8-Val-Ala-PAB-Exatecan	Drug-Linker Conjugates for ADC	Cancer
Mal-PEG8-Val-Ala-PAB-Exatecan (Compound 9b) is an antibody-drug conjugate linker (ADC linker) that binds to Nectin-4 polypeptides conjugated to chemotherapeutic agents. Mal-PEG8-Val-Ala-PAB-Exatecan can be used for cancer research.

HY-148870

Maytansinoid B	ADC Cytotoxin	Cancer
Maytansinoid B is a kind of ADC Cytotoxin. Maytansinoid B can be used to conjugates with antibodies to form *Antibody-Drug Conjugates* (ADCs). Maytansinoids are known as antimitotic agents, binding to tubulin and inhibiting microtubule assembly. Maytansinoids induces G2/M arrest in the cell cycle to induce apoptosis**.

HY-128870

Mal-PEG2-VCP-Eribulin	Drug-Linker Conjugates for ADC	Cancer
Mal-PEG2-VCP-Eribulin consists the ADCs linker (Mal-PEG2-VCP) and Eribulin. Eribulin is a mechanistically unique microtubule inhibitor for cancer. Mal-PEG2-VCP-Eribulin is an Eribulin-based drug for antibody conjugates.

HY-136033

Methyltetrazine-SS-NHS
ADC Linker Cancer

Methyltetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140987

5-Maleimidovaleric acid
ADC Linker Cancer

5-Maleimidovaleric acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140313

Methyltetrazine-DBCO
ADC Linker Cancer

Methyltetrazine-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130110

Sulfo-DMAC-SPP
ADC Linker Cancer

Sulfo-DMAC-SPP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140306

Mal-Sulfo-DBCO
ADC Linker Cancer

Mal-Sulfo-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W019543

DSS Crosslinker
ADC Linker Cancer

DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140105

Azidoethyl-SS-ethylazide
ADC Linker Cancer

Azidoethyl-SS-ethylazide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141158

N-(Iodoacetamido)-Doxorubicin
ADC Linker Cancer

N-(Iodoacetamido)-Doxorubicin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136031

Tetrazine-SS-Biotin
ADC Linker Cancer

Tetrazine-SS-Biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140100

Azidoethyl-SS-propionic acid
ADC Linker Cancer

Azidoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140296

BDP FL DBCO
ADC Linker Cancer

BDP FL DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-138327

1,6-Bis(mesyloxy)hexane
ADC Linker Cancer

16-Bismesyloxyhexane is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135973

BCN-SS-NHS
ADC Linker Cancer

BCN-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136032

Tetrazine-SS-NHS
ADC Linker Cancer

Tetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135978

DBCO-SS-amine
ADC Linker Cancer

DBCO-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135972

BCN-SS-amine
ADC Linker Cancer

BCN-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140096

Aminoethyl-SS-propionic acid
ADC Linker Cancer

Aminoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126851

Fluorescein-DBCO
ADC Linker Cancer

Fluorescein-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126518

Cyclooctyne-O-PFP ester
ADC Linker Cancer

Cyclooctyne-O-PFP ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-101540

NMI 8739
Dopamine Receptor Neurological Disease

NMI 8739 is a dopamine D₂ autoreceptor agonist, which is an amine conjugate of the DHA carrier and the neurotransmitter dopamine.
HY-W096127

Biotin-sar-oh
ADC Linker Cancer

Biotin-sar-oh is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130928

Tetrazine-Ph-OPSS
ADC Linker Cancer

Tetrazine-Ph-OPSS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-128929

Fmoc-PEA
ADC Linker Cancer

Fmoc-PEA (Example 1-2) is a used as a cleavable linker for antibody-drug conjugates (ADC).
HY-140122

THP-SS-alcohol
ADC Linker Cancer

THP-SS-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135418

Fmoc-Asp-NH2
ADC Linker Cancer

Fmoc-Asp-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140104

Azidoethyl-SS-ethylamine
ADC Linker Cancer

Azidoethyl-SS-ethylamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-138506

DBCO-S-S-acid
ADC Linker Cancer

DBCO-S-S-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129360

Ala-Ala-Asn-PAB
ADC Linker Cancer

Ala-Ala-Asn-PAB is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs).
HY-D0078

DCIA
Fluorescent Dye Others

DCIA is a fluorescent dye. DCIA contains a coumarin fluorophore and conjugates specifically with free cysteines in the protein.

HY-141862

Zanamivir-Cholesterol Conjugate	Influenza Virus	Infection
Zanamivir–cholesterol conjugate is a long-acting neuraminidase inhibitor with potent efficacy against drug-resistant influenza viruses.

HY-135977

DBCO-SS-aldehyde
ADC Linker Cancer

DBCO-SS-aldehyde is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-131084

DMAC-SPDB-sulfo
ADC Linker Cancer

DMAC-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W011541

SIA Crosslinker
ADC Linker Cancer

SIA Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W002213

N-Hydroxysulfosuccinimide sodium
ADC Linker Cancer

N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140129

NHS-SS-biotin
ADC Linker Cancer

NHS-SS-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136039

TCO-SS-amine
ADC Linker Cancer

TCO-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-150043

MDTF free acid
ADC Linker Cancer

MDTF free acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-114233

MC-GGFG-Exatecan MC-GGFG-DX8951	Drug-Linker Conjugates for ADC	Cancer
MC-GGFG-Exatecan (MC-GGFG-DX8951) is a drug-linker conjugate for ADC. MC-GGFG-Exatecan is a DX8951 (a DNA topoisomerase I inhibitor) derivative with protease cleavable MC-GGFG linker. MC-GGFG-Exatecan shows antitumor activity and can be used to prepare DX8951 antibody conjugate (ADC).

HY-130572

Azido-PEG5-acid	PROTAC Linkers ADC Linker	Cancer Inflammation/Immunology
Azido-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs, such as the conjugate CPT-APO (CPT: Camptothecin (HY-16560)). Azido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-128527

PROTAC ER Degrader-3	PROTACs Estrogen Receptor/ERR	Cancer
PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC, consists the ADCs linker and PROTACs, conjugated to an antibody. PAC extracts from patent WO2017201449A1, compound LP2. PAC conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).

HY-141662

2',3'-cGAMP-C2-PPA	STING Drug-Linker Conjugates for ADC	Cancer
2',3'-cGAMP-C2-PPA (45), A cyclic di-nucleotide, is a STING agonist (US20210015941A1). 2',3'-cGAMP-C2-PPA is a *drug-linker conjugate* for ADC** that can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer.

HY-128528

PROTAC ER Degrader-2	PROTACs Estrogen Receptor/ERR	Cancer
PROTAC ER Degrader-2 is an intermediate for synthesis of PAC. PAC, consists the ADCs linker and PROTACs, conjugated to an antibody. PAC extracts from patent WO2017201449A1, compound LP2. PAC conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).

HY-130112

N-Succinimidyloxycarbonylpropyl methanethiosulfonate NHS-C4-MTS	ADC Linker	Cancer
N-Succinimidyloxycarbonylpropyl methanethiosulfonate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W440715

Cholesterol-PEG-Folate (MW 2000)
Liposome Others

Cholesterol-PEG-Folate (MW 2000) is an excipient and can be used for the preparation of folate-conjugated PEG-liposomes.
HY-124329

BS3 Crosslinker
ADC Linker Cancer

BS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130935

DBCO-Val-Cit-OH
ADC Linker Cancer

DBCO-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-101153

MC-Val-Ala-OH
ADC Linker Cancer

MC-Val-Ala-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126364

Mc-Val-Ala-PAB
ADC Linker Cancer

Mc-Val-Ala-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140138

PC SPDP-NHS carbonate ester
ADC Linker Cancer

PC SPDP-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136102

Py-ds-Prp-Osu
ADC Linker Cancer

Py-ds-Prp-Osu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140102

Azidoethyl-SS-propionic NHS ester
ADC Linker Cancer

Azidoethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-128962

AZ1508 MC-Lys-MMETA	Drug-Linker Conjugates for ADC	Cancer
AZ1508 is a *drug-linker conjugates* for ADC** for the treatment of breast and stomach cancer, and the drug is a tubulin inhibitor.

HY-W023121

Fmoc-Gly-Gly-OH
ADC Linker Cancer

Fmoc-Gly-Gly-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141141

Boc-Val-Cit-PAB
ADC Linker Cancer

Boc-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-D1496

Fluorescent Red Mega 485 NHS-ester
Fluorescent Dye Others

Fluorescent Red Mega 485 NHS-ester is an amine conjugating fluorescent biolabel that can be used to label proteins.
HY-117409

Aminoethyl-SS-ethylalcohol
ADC Linker Cancer

Aminoethyl-SS-ethylalcohol is a glutathione cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126524

N3-Ph-NHS ester
ADC Linker Cancer

N3-Ph-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140140

PC Mal-NHS carbonate ester
ADC Linker Cancer

PC Mal-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-138322

N-trifluoroacetyl-β-alanyl chloride
ADC Linker Cancer

N-trifluoroacetyl-β-alanyl chloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-P99016A

Enfortumab vedotin-ejfv
Antibody-Drug Conjugates (ADCs) Cancer

Enfortumab vedotin-ejfv is an anti-Nectin-4 antibody-drug conjugate for the management of urothelial carcinoma.
HY-129362

Phe-Lys(Fmoc)-PAB
ADC Linker Cancer

Phe-Lys(Fmoc)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs).
HY-138387

6-Azido-hexylamine
ADC Linker Cancer

6-Azido-hexylamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-12454

DM4
Microtubule/Tubulin ADC Cytotoxin Cancer

DM4 is is an antitubulin agent that inhibit cell division. DM4 can be used in the preparation of antibody drug conjugate.
HY-129349

Phe-Lys(Trt)-PAB
ADC Linker Cancer

Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs).
HY-W038702

Boc-Val-Cit-OH
ADC Linker Cancer

Boc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-104025

SPB	Drug-Linker Conjugates for ADC	Inflammation/Immunology
SPB is a drug-linker conjugate for ADC with potent anti-inflammatory activity by using Xanthotoxol, linked via the ADC linker.

HY-133504

Tetrazine-Ph-SS-amine
ADC Linker Cancer

Tetrazine-Ph-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-114430

Fmoc-Phe-Lys(Boc)-PAB-PNP
ADC Linker Others

Fmoc-Phe-Lys(Boc)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130442

Mal-PEG2-acid	ADC Linker PROTAC Linkers	Cancer
Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule. Mal-PEG2-acid is also a PROTAC linker that can be used in the synthesis of PROTACs.

HY-130082

DM4-SMe	ADC Cytotoxin Microtubule/Tubulin	Cancer
DM4-SMe is a metabolite of *antibody-maytansin conjugates* (AMCs) and a tubulin inhibitor, and also a cytotoxic moiety of antibody-drug conjugates (ADCs), which can be linked to antibody through disulfide bond or stable thioether bond. DM4-SMe inhibits KB cells with an IC₅₀** of 0.026 nM.

HY-136170

MC-SN38	Drug-Linker Conjugates for ADC	Cancer
MC-SN38 is a drug-linker conjugate composed of a potent microtubule-disrupting agent SN38 and a non-cleavable MC linker to make antibody drug conjugate (ADC). SN-38, an active metabolite of the Topoisomerase I inhibitor Irinotecan, inhibits DNA synthesis and causes frequent DNA single-strand breaks.

HY-126353

Fmoc-Val-Ala-PAB-OH
ADC Linker Cancer

Fmoc-Val-Ala-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-44234

Fmoc-Gly-Gly-Phe-OtBu
ADC Linker Cancer

Fmoc-Gly-Gly-Phe-OtBu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130090

NHPI-PEG4-C2-Pfp ester
ADC Linker Cancer

NHPI-PEG4-C2-Pfp ester is used as a linker for antibody-drug conjugates (ADC).

HY-132938

(S,R,S)-AHPC-Me-decanedioic acid	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-Me-decanedioic acid is an E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACs.

HY-140116

Boc-NH-ethyl-SS-propionic acid
ADC Linker Cancer

Boc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-124329A

BS3 Crosslinker disodium
ADC Linker Cancer

BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130937

DBCO-Val-Cit-PABC-PNP
ADC Linker Cancer

DBCO-Val-Cit-PABC-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133412

DBCO-NHCO-S-S-NHS ester
ADC Linker Cancer

DBCO-NHCO-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130936

DBCO-Val-Cit-PABC-OH
ADC Linker Cancer

DBCO-Val-Cit-PABC-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141145

OPSS-Val-Cit-PAB-PNP
ADC Linker Cancer

OPSS-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-44222

MAC glucuronide linker-2
ADC Linker Cancer

MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130932

Boc-Val-Ala-PAB-PNP
ADC Linker Cancer

Boc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136136

Fmoc-Val-Ala-PAB-PNP
ADC Linker Cancer

Fmoc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140118

Fmoc-NH-ethyl-SS-propionic acid
ADC Linker Cancer

Fmoc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133413

DBCO-CONH-S-S-NHS ester
ADC Linker Cancer

DBCO-CONH-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126533

PDP-C1-Ph-Val-Cit
ADC Linker Cancer

PDP-C1-Ph-Val-Cit is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
HY-131833

Fmoc-Gly-Gly-Phe-OH
ADC Linker Cancer

Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141144

OPSS-Val-Cit-PAB-OH
ADC Linker Cancer

OPSS-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126670

mDPR(Boc)-Val-Cit-PAB
ADC Linker Cancer

mDPR(Boc)-Val-Cit-PAB is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC).
HY-141142

Boc-Val-Cit-PAB-PNP
ADC Linker Cancer

Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-139353

Fmoc-Phe-Lys(Boc)-PAB
ADC Linker Cancer

Fmoc-Phe-Lys(Boc)-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130098

Ald-Ph-amido-PEG3-C-COOH
ADC Linker Cancer

Ald-Ph-amido-PEG3-C-COOH is a noncleavable linker used for the antibody-drug conjugate (ADC).
HY-140117

Boc-aminooxy-ethyl-SS-propanol
ADC Linker Cancer

Boc-aminooxy-ethyl-SS-propanol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-138745

Bis-sulfone-PEG3-Azide
ADC Linker Cancer

Bis-sulfone-PEG3-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130930

Acid-propionylamino-Val-Cit-OH
ADC Linker Cancer

Acid-propionylamino-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140120

Mal-NH-ethyl-SS-propionic acid
ADC Linker Cancer

Mal-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140125

2-Hydroxyethyl disulfide mono-tosylate
ADC Linker Cancer

2-Hydroxyethyl disulfide mono-tosylate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-132251

MCC
ADC Linker Cancer

MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1.
HY-136139

3-Azidopropionic Acid Sulfo-NHS ester
ADC Linker Cancer

3-Azidopropionic Acid Sulfo-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126497

LC-PEG8-SPDP
ADC Linker Cancer

LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).
HY-136107

Fmoc-Phe-Lys(Trt)-PAB
ADC Linker Cancer

Fmoc-Phe-Lys(Trt)-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126663

N-Me-L-Ala-maytansinol
ADC Cytotoxin Cancer

N-Me-L-Ala-maytansinol is a hydrophobic, cell permeable payload used for making antibody-drug conjugate (ADC).
HY-135975

MC-Val-Ala-PAB-PNP
ADC Linker Cancer

MC-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-42360

SMCC
ADC Linker Cancer

SMCC is a protein crosslinker. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses.
HY-W071007

NO2-SPDMV
ADC Linker Cancer

NO2-SPDMV is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-139856

Mal-Ala-Ala-PAB-PNP
ADC Linker Cancer

Mal-Ala-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-100128

DM1-SMe	Microtubule/Tubulin ADC Cytotoxin	Cancer
DM1-SMe is an unconjugated form of the Maytansinoid in IMGN901. DM1-SMe is about 3-10-fold more potent than the parent drug Maytansine, with IC₅₀s ranging from 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell lines.

HY-W101718

Fmoc-N-(2-Boc-aminoethyl)-Gly-OH	Isotope-Labeled Compounds ADC Linker	Cancer
Fmoc-N-(2-Boc-aminoethyl)-Gly-OH is a Fmoc-protected glycine derivative that can be used in antibody drug coupling (ADC) synthesis. ADC consists of antibodies that are linked to ADC cytotoxins via ADC junctions[1].

HY-132161

MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT	Drug-Linker Conjugates for ADC	Cancer
MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT is a Camptothecin-linker compound extracted from patent WO2019195665A1, example 4-1. MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT is a *drug-linker conjugate* for antibody-drug conjugate (ADC)**.

HY-151207

Anticancer agent 81	Apoptosis ADC Cytotoxin	Cancer
Anticancer agent 81 (Compound 37b3) is an anticancer agent and can induce tumor cell cycle arrest and apoptosis. Anticancer agent 81 can be used as a payload to conjugate with Trastuzumab (HY-P9907) to obtain the antibody–drug conjugate (ADC) T-PBA. T-PBA maintained its mode of target and internalization ability of Trastuzumab.

HY-129834

*Bilirubin Conjugate* disodium**	Others	Metabolic Disease
Bilirubin Conjugate disodium is a ditaurate derivative of Bilirubin. Bilirubin, a major end product of heme breakdown, is an important constituent of bile.

HY-15742

Vc-MMAD	Microtubule/Tubulin Drug-Linker Conjugates for ADC	Cancer
Vc-MMAD consists the ADCs linker (Val-Cit) and potent tubulin inhibitor (MMAD). Vc-MMAD is a drug-linker conjugate for ADC.

HY-133547

NO2-SPP-sulfo
ADC Linker Cancer

NO2-SPP-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-14941

Elacytarabine CP 4055	Nucleoside Antimetabolite/Analog	Cancer
Elacytarabine (CP 4055) is a lipid-conjugated derivative of the nucleoside analog cytarabine. Elacytarabine (CP 4055) is an antineoplastic drug with cytotoxicity in solid tumors.

HY-23926

PYBG	Fluorescent Dye	Others
PYBG acts as a versatile precursor to be facilely conjugated with various fluorescent dyes through ‘Click chemistry’ and Sonogashira coupling reactions.

HY-129351

Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP
ADC Linker Cancer

Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133548

NO2-SPDB-sulfo
ADC Linker Cancer

NO2-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136132

MC-VC-PAB-NH2
ADC Linker Cancer

MC-VC-PAB-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136547

Boc-Val-Ala-PAB
ADC Linker Others

Boc-Val-Ala-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate (ADCs).
HY-129350

Fmoc-Phe-Lys(Trt)-PAB-PNP
ADC Linker Cancer

Fmoc-Phe-Lys(Trt)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130547

BS2G Crosslinker disodium
ADC Linker Cancer

BS2G Crosslinker (disodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129378

NO2-SPP-sulfo-Me
ADC Linker Cancer

NO2-SPP-sulfo-Me is a cleavable linker that is used for making antibody-drug conjugate (ADC).
HY-136125

BCOT-PEF3-OPFP
ADC Linker Cancer

BCOT-PEF3-OPFP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133549

NO2-SPDMV-sulfo
ADC Linker Cancer

NO2-SPDMV-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-128940

EC089
ADC Linker Cancer

EC089 is a cleavable linker used in conjugates of tubulysins and folates, and extracted from patent WO2011069116A1.
HY-138521

Azido-C6-OH
ADC Linker Cancer

Azido-C6-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-120903

DBCO-C3-Acid
ADC Linker Cancer

DBCO-C3-Acid is a Click Chemistry intermediate used in the synthesis of antibody-drug conjugate (ADC) linker.
HY-140119

Fmoc-NH-ethyl-SS-propionic NHS ester
ADC Linker Cancer

Fmoc-NH-ethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W011561

Boc-NH-C6-Br
ADC Linker Cancer

Boc-NH-C6-Br is a non-cleavable linker used for antibody-drug conjugates (ADC).
HY-130933

Fmoc-Ala-Ala-Asn(Trt)-OH
ADC Linker Cancer

Fmoc-Ala-Ala-Asn(Trt)-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-138535

Azide-C2-Azide
ADC Linker Cancer

Azide-C2-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126502

Mal-C2-NHS ester
ADC Linker Cancer

Mal-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136329

β-D-glucuronide-pNP-carbonate
ADC Linker Cancer

β-D-glucuronide-pNP-carbonate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W019939

Hydroxy-PEG10-Boc	ADC Linker	Cancer
Hydroxy-PEG10-Boc is extacted from patent CN108707228 (example 0024). Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel (HY-B0015) or docetaxel (HY-B0011).

HY-126523

N3-C5-NHS ester
ADC Linker Cancer

N3-C5-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136154

Fmoc-Glu-(Boc)-Val-Cit-PAB-PNP
ADC Linker Cancer

Fmoc-Glu-(Boc)-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126521

N3-C3-NHS ester
ADC Linker Cancer

N3-C3-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-141860

PSMA-Val-Cit-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
PSMA-Val-Cit-PAB-MMAE is a novel small-molecule PSMA-targeted conjugate based on the monomethyl auristatin E for the chemotherapy of prostate cancer.

HY-141143

MC(C5)-Val-Cit
ADC Linker Cancer

MC(C5)-Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126495A

Sulfo-SPDP-C6-NHS sodium
ADC Linker Cancer

Sulfo-SPDP-C6-NHS sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-145488

MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D	ADC Linker	Cancer
MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138651

PAB-Val-Lys-Boc	ADC Linker	Inflammation/Immunology
PAB-Val-Lys-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) for stimulating an immune response.

HY-130097

Ald-Ph-amido-PEG4-C2-acid
ADC Linker Cancer

Ald-Ph-amido-PEG4-C2-acid is a noncleavable linker used for the antibody-drug conjugate (ADC).
HY-112806

ST8155AA1
Drug-Linker Conjugates for ADC Cancer

ST8155AA1 is a part of antibody drug conjugates (ADCs) charged with HDAC inhibitor by a linker, shows antitumor activity.
HY-126522

N3-C4-NHS ester
ADC Linker Cancer

N3-C4-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133584

Bis-SS-C3-NHS ester
ADC Linker Cancer

Bis-SS-C3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-145593

Aminooxy-PEG2-BCN
ADC Linker Cancer

Aminooxy-PEG2-BCN is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-112805

ST8154AA1
Drug-Linker Conjugates for ADC Cancer

ST8154AA1 is a part of antibody drug conjugates (ADCs) charged with HDAC inhibitor by a linker, shows antitumor activity.
HY-126520

N3-C2-NHS ester
ADC Linker Cancer

N3-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-139107

Biotin-PEG4-SS-azide
ADC Linker Cancer

Biotin-PEG4-SS-azide is a cleavable, biotin-labeled, ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-137421

4-Nitrophenyl N-acetyl-α-D-glucosaminide
Others Others

4-Nitrophenyl N-acetyl-α-D-glucosaminide is a 4-nitrophenyl- conjugated substrate for determining the enzymatic specificity.

HY-102001

Tomaymycin DM	ADC Cytotoxin	Cancer
Tomaymycin DM, a DNA alkylator, is a derivative of Tomaymycin, it is a PBD dimer, which is attached to tumor targeting antibodies to create antibody-drug conjugates (ADCs).

HY-140126

Bis-Tos-(2-hydroxyethyl disulfide)
ADC Linker Cancer

Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-144001

DSPE-PEG-Carboxylic Acid	Liposome	Others
DSPE-PEG-Carboxylic Acid is a phospholipid PEG conjugate. DSPE-PEG-Carboxylic Acid can be widely used in the delivery of targeted drugs and genes.

HY-145720

Cemdisiran ALN-CC5	Small Interfering RNA (siRNA) Complement System	Others
Cemdisiran is an N-acetylgalactosamine (GalNAc) conjugated siRNA for the treatment of complement-mediated diseases by suppressing liver production of complement 5 (C5) protein.

HY-P3883

[DAla4] Substance P (4-11)	Neurokinin Receptor	Neurological Disease
[DAla4] Substance P (4-11) is an analog of Substance P (Substance P (HY-P0201)) that inhibits the binding of ¹²⁵I-Bolton Hunter-conjugated Eledoisin (Eledoisin (HY-P0006)) (IC₅₀ of 0.5 μM) and ¹²⁵I-Bolton Hunter-conjugated Substance P (IC₅₀ of 0.15 μM) to rat brain cortex membranes.

HY-P99956

Zilovertamab vedotin VLS-101; MK-2140	Antibody-Drug Conjugates (ADCs) Apoptosis	Cancer
Zilovertamab vedotin (VLS-101) is a novel antibody-drug conjugate comprising the humanized monoclonal antibody zilovertamab and and the anti-microtubule cytotoxin monomethyl vedotin. Zilovertamab vedotin binding to tumor cell ROR1 results in rapid internalization, trafficking to lysosomes, antibody–drug conjugate cleavage, and monomethyl vedotin release. Zilovertamab vedotin induces apoptosis. Zilovertamab vedotin can be used in research of cancer.

HY-111872

SNIPER(ABL)-020
SNIPERs Bcr-Abl Cancer

SNIPER(ABL)-020, conjugating Dasatinib (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein.
HY-132250

MCC-DM1
Drug-Linker Conjugates for ADC Cancer

MCC-DM1 is a drug-Linker Conjugates for ADC such ad Anti-CD22-MCC-DM1.
HY-145066

Gly-Gly-Gly-PEG4-azide
ADC Linker Cancer

Gly-Gly-Gly-PEG4-azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141355

OPSS-PEG36-acid
ADC Linker Cancer

OPSS-PEG36-acid is a cleavable 36 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-131086

Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2	ADC Linker	Cancer Inflammation/Immunology
Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-126883

Tr-PEG4-OH
PROTAC Linkers Cancer Inflammation/Immunology

Tr-PEG4-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-145489

Mal-PEG2-Val-Cit-PABA
ADC Linker Cancer

Mal-PEG2-Val-Cit-PABA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136106

Fmoc-Gly3-Val-Cit-PAB
ADC Linker Cancer

Fmoc-Gly3-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136432

Mc-Gly-Gly-Phe-Gly-PAB-OH
Mc-GGFG-PAB-OH
ADC Linker Cancer

Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
HY-141123

SPDP-C6-Gly-Leu-NHS ester
ADC Linker Cancer

SPDP-C6-Gly-Leu-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-D1112

TFAX 546,SE triethylammonium	Fluorescent Dye	Others
TFAX 546,SE triethylammonium, an amine reactive yellow fluorescent dye, can forms bright and photostable conjugates with proteins and antibodies.

HY-144630

diSPhMC-Asn-Pro-Val-PABC-MMAE
ADC Linker Cancer

diSPhMC-Asn-Pro-Val-PABC-MMAE (compound 9) is a potent ADC Linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133408

4-Methyl-4-(methyldisulfanyl)pentanoic acid	ADC Linker	Cancer
4-Methyl-4-(methyldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-144629

Asn-Pro-Val-PABC-MMAE TFA
ADC Linker Cancer

Asn-Pro-Val-PABC-MMAE TFA (compound 8) is a potent ADC Linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126525

4-N3Pfp-NHS ester
ADC Linker Cancer

4-N3Pfp-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129311

Tr-PEG6-OH
ADC Linker Cancer Inflammation/Immunology

Tr-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133585

Bis-SS-C3-sulfo-NHS ester
ADC Linker Cancer

Bis-SS-C3-sulfo-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-145367

Ala-CO-amide-C4-Boc
ADC Linker Cancer

Ala-CO-amide-C4-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-120258

Tr-PEG3-OH
ADC Linker Cancer Inflammation/Immunology

Tr-PEG3-OH is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-115374

m-PEG6-azide
ADC Linker Cancer Inflammation/Immunology

m-PEG6-azide is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141353

SPDP-PEG12-acid
ADC Linker Cancer

SPDP-PEG12-acid is a cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-145148

Hemiasterlin derivative-1	ADC Cytotoxin	Cancer
Hemiasterlin derivative-1 is a hemiasterlin derivative. Hemiasterlin derivative-1 can be used for the synthesis of the Antibody-drug conjugate (ADC).

HY-135971

BCN-PEG4-acid
ADC Linker Cancer

BCN-PEG4-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W019793

m-PEG8-NHS ester
ADC Linker Cancer Inflammation/Immunology

m-PEG8-NHS ester is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-KT001

*E3 Ligase Ligand-Linker Conjugate* Kit**	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-Linker Conjugate Kit is a series of synthesized compounds that incorporate an E3 ligase ligand and a linker used in PROTAC technology.

HY-136051

Biotin-PEG3-aldehyde
ADC Linker Cancer

Biotin-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-141594

Modified MMAF	Microtubule/Tubulin	Cancer
Modified MMAF, an ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). Modified MMAF can be used for the targeted treatment of cancer.

HY-P1449

Boc-Gly-Gly-Phe-Gly-OH	ADC Linker	Cancer
Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

HY-136099

Bocaminooxyacetamide-PEG2-Azido
ADC Linker Cancer

Bocaminooxyacetamide-PEG2-Azido is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136044

APN-PEG4-BCN
ADC Linker Cancer

APN-PEG4-BCN is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-131156

Mal-PEG2-Val-Cit-PABA-PNP
ADC Linker Cancer

Mal-PEG2-Val-Cit-PABA-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136309

Ald-PEG23-SPDP
ADC Linker Cancer

Ald-PEG23-SPDP is a cleavable 23 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-148142

Pomalidomide-C3-NHS ester	E3 Ligase Ligand-Linker Conjugates	Others
Pomalidomide-C3-NHS ester is a synthesized E3 ligase ligand-linker conjugate, incorporating the Pomalidomide based cereblon ligand and NHS ester linker.

HY-140115

Bis-(PEG6-acid)-SS
ADC Linker Cancer

Bis-(PEG6-acid)-SS is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136052

Tetrazine-PEG4-oxyamine hydrochloride	ADC Linker	Cancer
Tetrazine-PEG4-oxyamine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138484

Folate-PEG3-amine
ADC Linker Cancer

Folate-PEG3-amine is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135961

PTAD-PEG4-amine
ADC Linker Cancer

PTAD-PEG4-amine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136086

Tetrazine-PEG6-amine hydrochloride	ADC Linker	Cancer
Tetrazine-PEG6-amine (hydrochloride) is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-148211

Tetrazine-PEG7-amine hydrochloride
ADC Linker Cancer

Tetrazine-PEG7-amine hydrochloride is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W020215

Tricarballylic acid	Mitochondrial Metabolism Endogenous Metabolite	Inflammation/Immunology
Tricarballylic acid, a conjugate acid of a tricarballylate, is a competitive inhibitor of the enzyme aconitate hydratase (aconitase; EC 4.2.1.3) with a K_i value of 0.52 mM.

HY-136049

APN-PEG4-DBCO
ADC Linker Cancer

APN-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-116655

Hydroxy-PEG1-acid
ADC Linker Cancer

Hydroxy-PEG1-acid is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W096133

Biotin-PEG1-azide
ADC Linker Cancer

Biotin-PEG1-azide is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135974

Amino-PEG3-SS-acid
ADC Linker Cancer

Amino-PEG3-SS-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135125

DC4
ADC Cytotoxin Cancer

DC4, an ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4 can be used for the targeted treatment of cancer.
HY-140244

Gly-PEG3-amine
ADC Linker Cancer

Gly-PEG3-amine is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136046

PTAD-PEG4-alkyne
ADC Linker Cancer

PTAD-PEG4-alkyne is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140144

Mal-PEG1-Val-Cit-PAB-PNP
ADC Linker Cancer

Mal-PEG1-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140097

Amino-SS-PEG12-acid
ADC Linker Cancer

Amino-SS-PEG12-acid is a cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136045

APN-PEG4-tetrazine
ADC Linker Cancer

APN-PEG4-tetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136067

DBCO-PEG4-HyNic
ADC Linker Cancer

DBCO-PEG4-HyNic is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136048

Methylcyclopropene-PEG4-NHS
ADC Linker Cancer

Methylcyclopropene-PEG4-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136127

ALD-PEG4-OPFP
ADC Linker Cancer

ALD-PEG4-OPFP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-138488

Biotin-PEG4-PFP ester
ADC Linker Cancer

Biotin-PEG4-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-101141

sulfo-SPDB-DM4	Drug-Linker Conjugates for ADC	Cancer
sulfo-SPDB-DM4 is a *drug-linker conjugate* for ADC** by using the maytansinebased payload (DM4, an antitubulin agent) via the sulfo-SPDB linker.

HY-136077

TCO-PEG3-aldehyde
ADC Linker Cancer

TCO-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-148143

Pomalidomide-C6-NHS ester	E3 Ligase Ligand-Linker Conjugates	Others
Pomalidomide-C6-NHS ester is a synthesized E3 ligase ligand-linker conjugate, incorporating the Pomalidomide based cereblon ligand and NHS ester linker.

HY-132858

Thalidomide-4-O-C10-COOH
E3 Ligase Ligand-Linker Conjugates Cancer

Thalidomide-4-O-C10-COOH is a E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACs.
HY-136061

BCN-PEG4-HyNic
ADC Linker Cancer

BCN-PEG4-HyNic is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135964

(2-pyridyldithio)-PEG4 acid
ADC Linker Cancer

(2-pyridyldithio)-PEG4 acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136050

TCO-PEG3-Biotin
ADC Linker Cancer

TCO-PEG3-Biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136075

HyNic-PEG4-alkyne
ADC Linker Cancer

HyNic-PEG4-alkyne is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-116063

Doxorubicin-SMCC	Drug-Linker Conjugates for ADC	Cancer
Doxorubicin-SMCC is a *drug-linker conjugate* for ADC**. Doxorubicin-SMCC contains a non-cleavable ADC linker and a DNA topoisomerase II inhibitor Doxorubicin.

HY-136047

Methylcyclopropene-PEG3-amine
ADC Linker Cancer

Methylcyclopropene-PEG3-amine is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136101

Bocaminooxyacetamide-PEG3-alkyne
ADC Linker Cancer

Bocaminooxyacetamide-PEG3-alkyne is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136074

Methyltetrazine-PEG4-aldehyde
ADC Linker Cancer

Methyltetrazine-PEG4-aldehyde is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141358

SPDP-PEG36-NHS ester
ADC Linker Cancer

SPDP-PEG36-NHS ester is a cleavable 36 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130939

APN-PEG4-Amine hydrochloride
ADC Linker Cancer

APN-PEG4-Amine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-111606

DUPA	Ligands for Target Protein for PROTAC	Cancer
DUPA, belongs to a class of glutamate ureas, is used as the targeting moiety in drug conjugate to selectively deliver cytotoxic drugs to prostate cancer cells.

HY-132163

MP-PEG4-VK(Boc)G-OSu
ADC Linker Cancer

MP-PEG4-VK(Boc)G-OSu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136053

Tetrazine-PEG4-biotin
ADC Linker Cancer

Tetrazine-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130977

Tetrazine-PEG4-amine hydrochloride	ADC Linker	Cancer
Tetrazine-PEG4-amine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-140352

Azide-PEG5-Tos
ADC Linker Cancer

Azide-PEG5-Tos is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136038

Azido-PEG3-SSPy
ADC Linker Cancer

Azido-PEG3-SSPy is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136432A

Mc-Gly-Gly-Phe-Gly-PAB-OH TFA
Mc-GGFG-PAB-OH TFA
ADC Linker Cancer

Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
HY-132086

(2-Pyridyldithio)-PEG6 acid
ADC Linker Cancer

2-Pyridyldithio-PEG6 acid is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136056

Methyltetrazine-PEG4-oxyamine
ADC Linker Cancer

Methyltetrazine-PEG4-oxyamine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-132164

Gly-7-MAD-MDCPT	Others	Cancer
Gly-7-MAD-MDCPT (compound 4b) is an anticancer agent. Gly-7-MAD-MDCPT is a Camptothecin (HY-16560) compound, it shows cytotoxicity to various cancer cells with IC₅₀ values of 10-1000 nM.

HY-D0167

NHS-5(6)Carboxyrhodamine	Fluorescent Dye	Others
NHS-5(6)Carboxyrhodamine is a dye used for fluorescence labeling applications, where accurate dye/protein ratios can be obtained under native conditions.

HY-P99740

Mirzotamab	ADC Antibody	Cancer
Mirzotamab is an IgG1κ antibody targeting to CD276/B7-H3. Mirzotamab can conjugates with Clezutoclaxum (HY-137774), an BCL2L1 inhibitor to form Mirzotamab clezutoclax (HY-P99741), involving in research with taxane therapy in relapsed/refractory solid tumors. Mirzotamab clezutoclax (ABBV-155) is a targeted *antibody drug conjugate* (ADC)**.

HY-129776

*K-Ras ligand-Linker Conjugate* 2**	Target Protein Ligand-Linker Conjugates	Cancer
K-Ras ligand-Linker Conjugate 2 incorporates a ligand for K-Ras, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 2 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells.

HY-129775

*K-Ras ligand-Linker Conjugate* 1**	Target Protein Ligand-Linker Conjugates	Cancer
K-Ras ligand-Linker Conjugate 1 incorporates a ligand for K-Ras, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 1 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells.

HY-W034595

Eicosanedioic acid	ADC Linker PROTAC Linkers	Cancer
Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis

HY-130925

BCN-PEG4-OH
ADC Linker Cancer

BCN-PEG4-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130080

DM3 Maytansinoid DM3	ADC Cytotoxin Microtubule/Tubulin	Cancer
DM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of *antibody-drug conjugates* (ADCs)**.

HY-111858

SNIPER(ABL)-050
SNIPERs Bcr-Abl Cancer

SNIPER(ABL)-050, conjugating Imatinib (ABL inhibitor) to MV-1 (IAP ligand) with a linker, induces the reduction of BCR-ABL protein.
HY-140078

bis-PEG2-endo-BCN
ADC Linker Cancer

bis-PEG2-endo-BCN is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133431

DBCO-PEG3-SS-NHS ester
ADC Linker Cancer

DBCO-PEG3-SS-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-135962

Boc-Aminooxy-PEG2-bromide
ADC Linker Cancer

Boc-Aminooxy-PEG2-bromide is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140124

THP-SS-PEG1-Tos
ADC Linker Cancer

THP-SS-PEG1-Tos is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130924

BCN-PEG3-Biotin
ADC Linker Cancer

BCN-PEG3-Biotin is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-D0098

Fluorescein-5-maleimide N-(5-Fluoresceinyl)maleimide	Fluorescent Dye	Others
Fluorescein-5-maleimide is a fluorescent thiol-reactive dye used to conjugate fluorescein to proteins (excitation: 494 nm, emission: 519 nm). Storage: protect from light.

HY-135966

Azido-PEG3-SS-NHS
ADC Linker Cancer

Azido-PEG3-SS-NHS is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130926

BCN-PEG3-oxyamine
ADC Linker Cancer

BCN-PEG3-oxyamine is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136041

Boc-amino-PEG3-SSPy
ADC Linker Cancer

Boc-amino-PEG3-SSPy is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140130

PC Biotin-PEG3-alkyne
ADC Linker Cancer

PC Biotin-PEG3-alkyne is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140123

THP-SS-PEG1-Boc
ADC Linker Cancer

THP-SS-PEG1-Boc is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130927

BCN-PEG4-Ts
ADC Linker Cancer

BCN-PEG4-Ts is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133466

Methyltetrazine-PEG4-SS-NHS ester
ADC Linker Cancer

Methyltetrazine-PEG4-SS-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140108

Propargyl-PEG1-SS-alcohol
ADC Linker Cancer

Propargyl-PEG1-SS-alcohol is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-N0324A

Cholic acid sodium	Endogenous Metabolite	Metabolic Disease
Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid sodium is orally active.

HY-128959

MCC-Modified Daunorubicinol	Drug-Linker Conjugates for ADC	Cancer
Daunorubicinol is a *drug-linker conjugate* for ADC** with potent antitumor activity by using Aur0101 (DNA Topoisomerase II inhibitor), linked via the ADC linker.

HY-136035

Methyltetrazine-SS-PEG4-Biotin
ADC Linker Cancer

Methyltetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133434

Aminoxyacetamide-PEG3-azide
ADC Linker Cancer

Aminoxyacetamide-PEG3-azide is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133428

DBCO-PEG3-TCO
ADC Linker Cancer

DBCO-PEG3-TCO is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-P1449A

Boc-Gly-Gly-Phe-Gly-OH TFA	ADC Linker	Cancer
Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

HY-136096

DBCO-PEG3 acetic-EVCit-PAB
ADC Linker Cancer

DBCO-PEG3 acetic-EVCit-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-139345

(S,R,S)-AHPC-CO-C9-acid VH032-NH-CO-C9-acid	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-CO-C9-acid is an E3 ligase ligand-linker conjugate that can be connected to the ligand for protein to form PROTACs.

HY-133430

DBCO-PEG4-alkyne
ADC Linker Cancer

DBCO-PEG4-alkyne is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-132145

5-Propargylamino-ddUTP	DNA/RNA Synthesis	Others
5-Propargylamino-ddUTP, a nucleoside molecule that can be used to synthesis of cyanine dye-nucleotide conjugate which is used in nucleic acid labeling or sequence analysis.

HY-112561

Bis-PEG1-PFP ester
ADC Linker Cancer Inflammation/Immunology

Bis-PEG1-PFP ester is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-139325

NHS-Modified MMAF	Others	Others
NHS-Modified MMAF (WO2012143499A2, intermediat 210) is an intermediate which can be used for producing the anti-mesothelin binder-drug conjugates (ADCs).

HY-130955

Amino-bis-PEG3-TCO
ADC Linker Cancer

Amino-bis-PEG3-TCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140134

PC Biotin-PEG3-NHS ester
ADC Linker Cancer

PC Biotin-PEG3-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140152

BCN-PEG3-VC-PFP ester
ADC Linker Cancer

BCN-PEG3-VC-PFP ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136078

Tetrazine-diazo-PEG4-biotin
ADC Linker Cancer

Tetrazine-diazo-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133432

DBCO-PEG4-SS-TCO
ADC Linker Cancer

DBCO-PEG4-SS-TCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-126532

Fmoc-Val-Cit-PAB-Duocarmycin TM	Drug-Linker Conjugates for ADC	Cancer
Fmoc-Val-Cit-PAB-Duocarmycin TM is a *drug-linker conjugate* for ADC** by using the antitumor antibiotic, Duocarmycin TM, linked via Fmoc-Val-Cit-PAB.

HY-130945

Tetrazine-PEG5-SS-amine
ADC Linker Cancer

Tetrazine-PEG5-SS-amine is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130295

Pomalidomide-PEG2-Tos
E3 Ligase Ligand-Linker Conjugates Cancer

Pomalidomide-PEG2-Tos is an E3 ligase ligand-linker conjugates, composed of a cereblon ligand and two-unit PEG linker.
HY-130972

Amino-bis-PEG3-DBCO
ADC Linker Cancer

Amino-bis-PEG3-DBCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136087

Mal-bis-PEG3-DBCO
ADC Linker Cancer

Mal-bis-PEG3-DBCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136079

Methyltetrazine-PEG4-hydrazone-DBCO	ADC Linker	Cancer
Methyltetrazine-PEG4-hydrazone-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-140139

PC Alkyne-PEG4-NHS ester
ADC Linker Cancer

PC Alkyne-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136040

Tetrazine-PEG4-SS-NHS
ADC Linker Cancer

Tetrazine-PEG4-SS-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136085

Amino-bis-PEG3-BCN
ADC Linker Cancer

Amino-bis-PEG3-BCN is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136097

Maleimide-PEG2-hydrazide TFA
ADC Linker Cancer

Maleimide-PEG2-hydrazide (TFA) is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140930

Diazo Biotin-PEG3-DBCO
ADC Linker Cancer

Diazo Biotin-PEG3-DBCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-132146

5-Propargylamino-ddCTP	DNA/RNA Synthesis	Others
5-Propargylamino-ddCTP, a nucleoside molecule that can be used to synthesis of cyanine dye-nucleotide conjugate which is used in nucleic acid labeling or sequence analysis.

HY-136036

Tetrazine-SS-PEG4-Biotin
ADC Linker Cancer

Tetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-N0324

Cholic acid	Endogenous Metabolite	Metabolic Disease
Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active.

HY-133427

Propargyl-PEG4-hydrazide
ADC Linker Cancer

Propargyl-PEG4-hydrazide is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138783

Thalidomide-Piperazine-Piperidine	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-Piperazine-Piperidine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-133429

DBCO-PEG3-oxyamine
ADC Linker Cancer

DBCO-PEG3-oxyamine is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136037

Boc-amino-PEG3-SS-acid
ADC Linker Cancer

Boc-amino-PEG3-SS-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140944

Biotin-PEG3-SS-azide
ADC Linker Cancer

Biotin-PEG3-SS-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140132

PC Biotin-PEG3-azide
ADC Linker Cancer

PC Biotin-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130947

Tetrazine-PEG4-SS-Py
ADC Linker Cancer

Tetrazine-PEG4-SS-Py is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-138508

Biotin-PEG2-methyl ethanethioate
ADC Linker Cancer

Biotin-PEG2-methyl ethanethioate is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140136

PC DBCO-PEG3-biotin
ADC Linker Cancer

PC DBCO-PEG3-biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-78933

Fmoc-MMAE	Microtubule/Tubulin ADC Cytotoxin	Cancer
Fmoc-MMAE is a protective group-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Fmoc-MMAE can be used in the synthesis of ADC.

HY-135979

DBCO-SS-PEG4-Biotin
ADC Linker Cancer

DBCO-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130822

*K-Ras ligand-Linker Conjugate* 4**	Target Protein Ligand-Linker Conjugates	Cancer
K-Ras ligand-Linker Conjugate 4 incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 4 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells.

HY-130823

*K-Ras ligand-Linker Conjugate* 5**	Target Protein Ligand-Linker Conjugates	Cancer
K-Ras ligand-Linker Conjugate 5 incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 5 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells.

HY-130991

*K-Ras ligand-Linker Conjugate* 6**	Target Protein Ligand-Linker Conjugates	Cancer
K-Ras ligand-Linker Conjugate 6 incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 6 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells.

HY-130707

*K-Ras ligand-Linker Conjugate* 3**	Target Protein Ligand-Linker Conjugates	Cancer
K-Ras ligand-Linker Conjugate 3 (Compound 001371) incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 3 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells.

HY-144120

αGalCer-RBD	SARS-CoV	Infection
αGalCer-RBD is a self-adjuvanting lipoprotein conjugate. αGalCer-RBD induces potent immunity against SARS-CoV-2 and its variants of concern. αGalCer-RBD conjugate induces RBD-specific, cytokine-producing T cell development. αGalCer-RBD has great potential to be an effective COVID-19 vaccine candidate. α-Galactosylceramide (αGalCer) is a potent invariant natural killer T cell (iNKT) agonist. RBD: receptor-binding domain

HY-N0324B

Cholic acid sodium hydrate	Endogenous Metabolite	Metabolic Disease
Cholic acid sodium hydrate is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. Cholic acid sodium hydrate facilitates fat absorption and cholesterol excretion. Cholic acid sodium hydrate is orally active.

HY-130934

TCO-PEG1-Val-Cit-OH
ADC Linker Cancer

TCO-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140309

Gly-Gly-Gly-PEG4-DBCO
ADC Linker Cancer

Gly-Gly-Gly-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141190

Gly-Gly-Gly-PEG3-TCO
ADC Linker Cancer

Gly-Gly-Gly-PEG3-TCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-D1556

DOPE-CF	Fluorescent Dye	Others
DOPE-CF is a pH-sensitive fluorescent membrane labelled probe with a fluorescein moiety that is a weak acid and a conjugated base that is highly fluorescent and can be attached to phospholipid ethanolamine lipids.

HY-141292

Oleoyl-Gly-Lys-N-(m-PEG11)
ADC Linker Cancer

Oleoyl-Gly-Lys-N-(m-PEG11) is a cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-148461

Mal-VC-PAB-PNP
ADC Linker Cancer

Mal-VC-PAB-PNP is a cleavable ADC linker (ADC Linker). Mal-VC-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs).
HY-136134

SS-bis-amino-PEG4-NHS ester
ADC Linker Cancer

SS-bis-amino-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-132939

2-(2,6-Dioxopiperidin-3-yl)phthalimidine-C5-Br	E3 Ligase Ligand-Linker Conjugates	Cancer
2-(2,6-Dioxopiperidin-3-yl)phthalimidine-C5-Br is a E3 ligase ligand-linker conjugate for PROTAC.

HY-136034

Azido-PEG1-Val-Cit-OH
ADC Linker Cancer

Azido-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-W096135

Biotin-PEG1-NH2
ADC Linker Cancer

Biotin-PEG1-NH2 is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-148463

MP-Ala-Ala-PAB
ADC Linker Cancer

MP-Ala-Ala-PAB is a cleavable ADC linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs).
HY-126510

MC-PEG2-C2-NHS ester
ADC Linker Cancer

MC-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136135

(2-pyridyldithio)-PEG1-hydrazine
ADC Linker Cancer

(2-pyridyldithio)-PEG1-hydrazine is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133544

Mal-CO-PEG5-NHS ester
ADC Linker Cancer

Mal-CO-PEG5-NHS ester is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-148462

Fmoc-Ala-Ala-PAB
ADC Linker Cancer

Fmoc-Ala-Ala-PAB is a cleavable ADC linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs).
HY-130940

PTAD-PEG4-N3
ADC Linker Cancer

PTAD-PEG4-N3 is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130922

BCN-PEG1-Val-Cit-OH
ADC Linker Cancer

BCN-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-148464

MC-Ala-Ala-PAB
ADC Linker Cancer

MC-Ala-Ala-PAB is a cleavable ADC linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs).
HY-140127

Azide-C2-SS-C2-biotin
ADC Linker Cancer

Azide-C2-SS-C2-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130094

NHPI-PEG2-C2-Pfp ester
ADC Linker Cancer

NHPI-PEG2-C2-Pfp ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140099

Amino-ethyl-SS-PEG3-NHBoc
ADC Linker Cancer

Amino-ethyl-SS-PEG3-NHBoc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141284

Gly-Gly-Gly-PEG4-methyltetrazine
ADC Linker Cancer

Gly-Gly-Gly-PEG4-methyltetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133435

Aminooxy-amido-PEG4-propargyl
ADC Linker Cancer

Aminooxy-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-117371

Hemiasterlin (-)-Hemiasterlin; Milnamide B	ADC Cytotoxin	Cancer
Hemiasterlin ((-)-Hemiasterlin) is an antimitotic marine natural product with potent anticancer effcts. Hemiasterlin can be used as a cytotoxic payload (ADC Cytotoxin) in antibody-drug conjugates (ADCs).

HY-130095

NHPI-PEG2-C2-NHS ester
ADC Linker Cancer

NHPI-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133538

4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene	ADC Linker	Cancer
4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136141

DBCO-PEG3-propionic EVCit-PAB
ADC Linker Cancer

DBCO-PEG3-propionic EVCit-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-N1420AS

Rhamnose-13C monohydrate L-Rhamnose-¹³C (monohydrate)	Endogenous Metabolite	Cancer
Rhamnose-¹³C (monohydrate) is the ¹³C labeled Rhamnose monohydrate. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies. Rhamnose monohydrate c

HY-130092

NHPI-PEG3-C2-Pfp ester
ADC Linker Cancer

NHPI-PEG3-C2-Pfp ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130093

NHPI-PEG3-C2-NHS ester
ADC Linker Cancer

NHPI-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130640

(S,R,S)-AHPC-Me-C7 ester
E3 Ligase Ligand-Linker Conjugates Cancer

(S,R,S)-AHPC-Me-C7 ester is a E3 ligase ligand-linker conjugate used to synthesise BCL-X_L PROTAC degraders.
HY-133459

Mal-PEG1-Val-Cit-OH
ADC Linker Cancer

Mal-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130962

Ald-Ph-amido-PEG23-OPSS
ADC Linker Cancer

Ald-Ph-amido-PEG23-OPSS is a cleavable 23 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130954

Hynic-PEG3-N3
ADC Linker Cancer

Hynic-PEG3-N3 is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130941

Fmoc-N-bis-PEG3-NH-Boc
ADC Linker Cancer

Fmoc-N-bis-PEG3-NH-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140145

Mal-PEG4-Val-Cit-PAB-PNP
ADC Linker Cancer

Mal-PEG4-Val-Cit-PAB-PNP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136137

Azide-PEG1-Val-Cit-PABC-OH
ADC Linker Cancer

Azide-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140148

Azido-PEG3-Val-Cit-PAB-OH
ADC Linker Cancer

Azido-PEG3-Val-Cit-PAB-OH is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133576

Cyclooctyne-O-amido-PEG4-PFP ester	ADC Linker	Cancer
Cyclooctyne-O-amido-PEG4-PFP ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133575

Cyclooctyne-O-amido-PEG3-PFP ester	ADC Linker	Cancer
Cyclooctyne-O-amido-PEG3-PFP ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-141150

Azido-PEG5-Ala-Ala-Asn-PAB
ADC Linker Cancer

Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-77641

Cinnamoylglycine	Endogenous Metabolite	Metabolic Disease
Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine is used as a potential urinary biomarker indicating intact or disrupted colonization resistance during and after antibiotic treatment.

HY-Y1055

Guanine 2-Aminohypoxanthine	DNA/RNA Synthesis Endogenous Metabolite	Cancer
Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.

HY-133545

Mal-Ph-CONH-PEG4-NHS ester
ADC Linker Cancer

Mal-Ph-CONH-PEG4-NHS ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136100

TCO-PEG1-Val-Cit-PABC-PNP
ADC Linker Cancer

TCO-PEG1-Val-Cit-PABC-PNP is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136108

Fmoc-Gly3-Val-Cit-PAB-PNP
ADC Linker Cancer

Fmoc-Gly3-Val-Cit-PAB-PNP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141149

Fmoc-PEG4-Ala-Ala-Asn-PAB
ADC Linker Cancer

Fmoc-PEG4-Ala-Ala-Asn-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-12460

SPDB-DM4	Drug-Linker Conjugates for ADC	Cancer
SPDB-DM4 is a *drug-linker conjugate* for ADC** by using the maytansinebased payload (DM4, a tubulin inhibitor) via a SPDB linker, exhibiting potent anti-tumor activity.

HY-140844

Thalidomide-O-PEG4-azide	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-PEG4-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-136157

Py-ds-dmBut-amido-PEG4-NHS ester
ADC Linker Cancer

Py-ds-dmBut-amido-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133426

Ald-Ph-amido-PEG4-propargyl Ald-benzyl-amide-PEG4-propargyl	ADC Linker	Cancer
Ald-Ph-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-140113

Acid-PEG3-SS-PEG3-acid
ADC Linker Cancer

Acid-PEG3-SS-PEG3-acid is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130966

TCO-PEG1-Val-Cit-PABC-OH
ADC Linker Cancer

TCO-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-P99718

Lupartumab BAY 1112623	ADC Antibody	Cancer
Lupartumab (BAY 1112623) is an anti-LYPD3 (C4.4A) monoclonal antibody that can be used for the synthesis of antibody-drug conjugate BAY 1129980.

HY-N0324S

Cholic acid-d4	Endogenous Metabolite	Metabolic Disease
Cholic acid-d₄ is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

HY-130091

NHPI-PEG4-C2-NHS ester
ADC Linker Cancer

NHPI-PEG4-C2-NHS ester, example 40 (WO2014185985A1), is used as a linker for antibody-drug conjugates (ADC).

HY-136155

Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester	ADC Linker	Cancer
Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136098

DBCO-PEG4-acetic-Val-Cit-PAB
ADC Linker Cancer

DBCO-PEG4-acetic-Val-Cit-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136054

N3-PEG5-aldehyde
ADC Linker Cancer

N3-PEG5-aldehyde is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140143

Mal-PEG4-Val-Cit-PAB-OH
ADC Linker Cancer

Mal-PEG4-Val-Cit-PAB-OH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-112901

DC41
ADC Cytotoxin Cancer

DC41 is a DC1 derivative. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer.

HY-20336

Mc-Val-Cit-PABC-PNP Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate	ADC Linker	Cancer
Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC linker. Mc-Val-Cit-PABC-PNP can be used in the synthesis of antibody-drug conjugates (ADCs).

HY-141154

Amino-PEG4-Val-Cit-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
Amino-PEG4-Val-Cit-PAB-MMAE is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-131082

(R)-8-Azido-2-(Fmoc-amino)octanoic acid	ADC Linker	Cancer
(R)-8-Azido-2-(Fmoc-amino)octanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-106244A

DOTATATE acetate	Others	Cancer
DOTATATE acetate is a DOTA-conjugated peptide. DOTATATE acetate can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide therapy (PRRT).

HY-101152

SG3199-Val-Ala-PAB	Drug-Linker Conjugates for ADC	Cancer
SG3199-Val-Ala-PAB is an intermediate of Tesirine synthesis. Tesirine is a drug-linker conjugate for ADC which can be used for the research of several cancers.

HY-141010

Thalidomide-O-PEG4-amine	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-PEG4-amine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-131087

Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc	ADC Linker	Cancer
Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-150241

DOPE-NHS	Liposome	Others
DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery.

HY-N0324S1

Cholic acid-d5	Endogenous Metabolite	Metabolic Disease
Cholic acid-d₅ is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

HY-128896

Nitro-PDS-Tubulysin M	Drug-Linker Conjugates for ADC	Cancer
Nitro-PDS-Tubulysin M is a *drug-linker conjugate* for ADC** with potent antitumor activity by using Tubulysin M (a tubulin polymerization inhibitor), linked via the ADC linker Nitro-PDS.

HY-140112

Acid-PEG2-SS-PEG2-acid
ADC Linker Cancer

Acid-PEG2-SS-PEG2-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-D1546

Biotin-C2-maleimide	Fluorescent Dye	Cancer
Biotin-C2-maleimide is an antibody conjugate reagent, can bind to many biomolecules without significantly changing the biological activity of the target molecule.

HY-130944

Mal-PEG1-Val-Cit-PABC-OH
ADC Linker Cancer

Mal-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133436

Boc-aminooxy-amide-PEG4-propargyl	ADC Linker	Cancer
Boc-aminooxy-amide-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W041895

DL-Glutamic acid	Endogenous Metabolite	Others
DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability.

HY-133573

Cyclooctyne-O-amido-PEG2-PFP ester	ADC Linker	Cancer
Cyclooctyne-O-amido-PEG2-PFP ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-132973

MC-Val-Cit-PAB-NH-C2-NH-Boc
ADC Linker Cancer

MC-Val-Cit-PAB-NH-C2-NH-Boc is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133579

Ald-Ph-amido-PEG3-NHS ester
ADC Linker Cancer

Ald-Ph-amido-PEG3-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-15582

Auristatin E	Microtubule/Tubulin ADC Cytotoxin	Cancer
Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates. Auristatin E inhibits cell division by blocking the polymerisation of tubulin.

HY-126669

Mal-PEG4-VA
ADC Linker Cancer

Mal-PEG4-VA is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-VA is used for making antibody-drug conjugate.
HY-136103

DBCO-PEG4-Propionic-Val-Cit-PAB
ADC Linker Cancer

DBCO-PEG4-Propionic-Val-Cit-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-141014

Thalidomide-O-PEG4-Boc	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-PEG4-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-131185

Pomalidomide-amido-C3-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-amido-C3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-133409

4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid	ADC Linker	Cancer
4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136105

Azido-PEG1-Val-Cit-PABC-PNP
ADC Linker Cancer

Azido-PEG1-Val-Cit-PABC-PNP is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-111851

SNIPER(ABL)-049	SNIPERs Bcr-Abl	Cancer
SNIPER(ABL)-049, conjugating Imatinib (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC₅₀ of 100 μM.

HY-130923

BCN-PEG1-Val-Cit-PABC-OH
ADC Linker Cancer

BCN-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-N0324S2

Cholic acid-13C	Endogenous Metabolite	Metabolic Disease
Cholic acid-¹³C is the ¹³C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

HY-141155

endo-BCN-PEG4-Val-Cit-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138792

Glutarimide-Isoindolinone-NH-PEG2-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Glutarimide-Isoindolinone-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology.

HY-141151

Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB
ADC Linker Cancer

Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-112899

DC1	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin. DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer.

HY-P9980

Belantamab GSK2857914	TNF Receptor ADC Antibody	Cancer
Belantamab (GSK2857914) is a humanised IgG1 anti-BCMA (TNFRSF17) monoclonal antibody. Belantamab can be used in the synthesis of antibody-drug conjugate (ADC), Belantamab mafodotin.

HY-140147

Mal-amido-PEG2-Val-Cit-PAB-PNP
ADC Linker Cancer

Mal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-101162

SGD-1910	Drug-Linker Conjugates for ADC	Cancer
SGD-1910 is a *drug-linker conjugate* for ADC** by using the antitumor antibiotic, pyrrolobenzodiazepine (PBD, a cytotoxic DNA crosslinking), linked via the cleavable linker MC-Val-Ala.

HY-138783A

Thalidomide-Piperazine-Piperidine hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-Piperazine-Piperidine hydrochloride is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-Piperazine-Piperidine hydrochloride incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-141146

Mal-amido-PEG8-val-gly-PAB-OH
ADC Linker Cancer

Mal-amido-PEG8-val-gly-PAB-OH is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133572

Ald-Ph-amido-PEG11-NH-Boc
ADC Linker Cancer

Ald-Ph-amido-PEG11-NH-Boc is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138773

Thalidomide-PEG5-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-PEG5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-140146

Mal-amido-PEG2-Val-Cit-PAB-OH
ADC Linker Cancer

Mal-amido-PEG2-Val-Cit-PAB-OH is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-15942

5-TAMRA	Fluorescent Dye	Others
5-TAMRA (5-Carboxytetramethylrhodamine), SE and its conjugates yield bright, pH-insensitive orange-red fluorescence (approximate excitation/emission maxima ~546/579) with good photostability.

HY-128873

Duocarmycin GA	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
Duocarmycin GA is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin GA can be used against multi-drug resistant cell lines.

HY-107770

Duocarmycin MB	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
Duocarmycin MB is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin MB can be used against multi-drug resistant cell lines.

HY-13631E

Deruxtecan	Drug-Linker Conjugates for ADC	Cancer
Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

HY-115524

DBCO-NHS ester 2	ADC Linker	Cancer
DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry.

HY-136317

MC-betaglucuronide-MMAE-1	Drug-Linker Conjugates for ADC	Cancer
MC-betaglucuronide-MMAE-1 is a *drug-linker conjugate* for ADC** with potent antitumor activity by using MMAE (a tubulin polymerization inhibitor), linked via the cleavable ADC linker MC-betaglucuronide.

HY-136321

MC-betaglucuronide-MMAE-2	Drug-Linker Conjugates for ADC	Cancer
MC-betaglucuronide-MMAE-2 is a *drug-linker conjugate* for ADC** with potent antitumor activity by using MMAE (a tubulin polymerization inhibitor), linked via the cleavable ADC linker MC-betaglucuronide.

HY-111860

SNIPER(ABL)-013	SNIPERs Bcr-Abl	Cancer
SNIPER(ABL)-013, conjugating GNF5 (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC₅₀ of 20 μM.

HY-132159

MC-AAA-NHCH2OCH2COOH
ADC Linker Cancer

MC-AAA-NHCH2OCH2COOH (compound 20) is a cleavable ADC linker that is used for making antibody-drug conjugate (ADC).
HY-130315

Br-PEG4-C2-Boc
ADC Linker PROTAC Linkers Cancer

Br-PEG4-C2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-126685

Mal-PEG4-VA-PBD	Drug-Linker Conjugates for ADC	Cancer
Mal-PEG4-VA-PBD is a drug-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via Mal-PEG4-VA.

HY-47018

BCN-HS-PEG2-VA-PABC-SG3199
ADC Linker Others

BCN-HS-PEG2-VA-PABC-SG3199 (Compound 4) is a pyrrolobenzodiazepine that can be used as a drug linker of antibody-drug conjugates (ADC).

HY-131874

Thalidomide-O-C7-acid	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C7-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-W096148

Biotin-C4-amide-C5-NH2
ADC Linker Cancer

Biotin-C4-amide-C5-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138790

Glutarimide-Isoindolinone-NH-PEG4-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Glutarimide-Isoindolinone-NH-PEG4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology.

HY-141015

Pomalidomide-PEG4-azide	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG4-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-138775

Thalidomide-PEG3-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-138774

Thalidomide-PEG4-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-PEG4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-126494

DM4-SMCC	Drug-Linker Conjugates for ADC	Cancer
DM4-SMCC is a *drug-linker conjugate* for ADC** with antitumor activity by using DM4 (an antitubulin agent), linked via the non-cleavable SMCC linker.

HY-18987

Duocarmycin MA	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
Duocarmycin MA is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin MA can be used against multi-drug resistant cell lines.

HY-140109

Propargyl-PEG1-SS-PEG1-acid
ADC Linker Cancer

Propargyl-PEG1-SS-PEG1-acid is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-126692

Mal-VC-PAB-ABAEP-Azonafide	Drug-Linker Conjugates for ADC	Cancer
Mal-VC-PAB-ABAEP-Azonafide is a *drug-linker conjugate* for ADC** with with potent antitumor activity by using Azonafide (a cytotoxin), linked via the ADC linker Mal-VC-PAB.

HY-148339

Fmoc-VAP-MMAE	Drug-Linker Conjugates for ADC	Others
Fmoc-VAP-MMAE is a *drug-linker conjugates* for ADC**. Fmoc-VAP-MMAE consists of an ADC linker and a tubulin inhibitor MMAE (HY-15162), with a protective Fmoc group.

HY-131876

Thalidomide-O-C3-acid	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C3-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-136076

TCO-PEG3-CH2-aldehyde
ADC Linker Cancer

TCO-PEG3-CH2-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138860

Thalidomide-O-C11-acid	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C11-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-131880

Thalidomide-O-C2-acid	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C2-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-131889

Thalidomide-O-C5-acid	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C5-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-138791

Glutarimide-Isoindolinone-NH-PEG3-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Glutarimide-Isoindolinone-NH-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology.

HY-140055

Thalidomide-PEG4-Propargyl	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-PEG4-Propargyl is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-136131

NH2-PEG4-hydrazone-DBCO
ADC Linker Cancer

NH2-PEG4-hydrazone-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-147179

INX-SM-56	ADC Cytotoxin	Inflammation/Immunology
INX-SM-56 is a cytotoxin that can be used for the synthesis of anti-VISTA antibody drug conjugate. VISTA: V-region Immunoglobulin-containing Suppressor of T cell Activation.

HY-N1420AS2

Rhamnose-13C-2 monohydrate L-Rhamnose-¹³C-2 (monohydrate)	Endogenous Metabolite	Cancer
Rhamnose-¹³C-2 (monohydrate) is the ¹³C labeled Rhamnose monohydrate. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies. Rhamnose monohydrate

HY-128906

MC-Val-Cit-PAB-Retapamulin	Drug-Linker Conjugates for ADC	Cancer
MC-Val-Cit-PAB-Retapamulin is a *drug-linker conjugate* for ADC** with potent antitumor activity by using Retapamulin (a ribosome inhibitor), linked via the ADC linker MC-Val-Cit-PAB.

HY-147193

Nampt-IN-10 TFA	NAMPT	Cancer
Nampt-IN-10 TFA (compound 4) is a Nicotinamide Phosphoribosyltransferase (NAMPT) inhibitor. Nampt-IN-10 TFA shows cellular potency to A2780 and CORL23 cells lines with IC₅₀s of 5 and 19 nM, respectively. Nampt-IN-10 TFA can be used as a novel non-antimitotic payload for ADCs.

HY-136133

NHS-PEG2-SS-PEG2-NHS
ADC Linker Cancer

NHS-PEG2-SS-PEG2-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140121

m-PEG6-SS-PEG6-methyl
ADC Linker Cancer

m-PEG6-SS-PEG6-methyl is a cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138771

Thalidomide-NH-PEG3-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-136058

N3-PEG4-amido-Lys(Fmoc)-acid
ADC Linker Cancer

N3-PEG4-amido-Lys(Fmoc)-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-147077

Cemdisiran, terminal sugar modification-	Complement System	Inflammation/Immunology
Cemdisiran, terminal sugar modification- is an investigational N-acetylgalactosamine-conjugated RNAi drug. Cemdisiran, a siRNA-targeting C5 mRNA, suppresses liver production of complement component C5.

HY-126529

N3-PEG3-C2-PFP ester
ADC Linker Cancer

N3-PEG3-C2-PFP ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-D0048

5-TAMRA-SE 5-TAMRA-NHS ester; 5-Carboxytetramethylrhodamine succinimidyl ester	Fluorescent Dye	Others
5-TAMRA-SE is an amine-reactive fluorescent agent, its conjugates yield bright, pH-insensitive orange-red fluorescence (approximate excitation/emission maxima ~546/579) with good photostability.

HY-138782

Thalidomide-Piperazine-PEG1-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-Piperazine-PEG1-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-141833

Bi-Mc-VC-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
Bi-Mc-VC-PAB-MMAE consists ADCs linker (Fmoc-Val-Cit-PAB) and potent tubulin inhibitor (MMAE). Bi-Mc-VC-PAB-MMAE is a drug-linker conjugate for ADC.

HY-135970

Alkyne-PEG4-SS-PEG4-alkyne
ADC Linker Cancer

Alkyne-PEG4-SS-PEG4-alkyne is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138778

Thalidomide-Propargyne-PEG1-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-Propargyne-PEG1-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-130968

Amino-PEG4-bis-PEG3-propargyl
ADC Linker Cancer

Amino-PEG4-bis-PEG3-propargyl is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138776

Thalidomide-Propargyne-PEG3-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-Propargyne-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-136088

Acid-PEG1-bis-PEG3-BCN
ADC Linker Cancer

Acid-PEG1-bis-PEG3-BCN is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-133581

Mal-PEG3-C1-NHS ester
ADC Linker Cancer

Mal-PEG3-C1-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130973

Mal-PEG4-bis-PEG4-propargyl
ADC Linker Cancer

Mal-PEG4-bis-PEG4-propargyl is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-130108

N3-PEG4-C2-Pfp ester
ADC Linker Cancer

N3-PEG4-C2-Pfp ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-P99593

Sofituzumab vedotin DMUC5754A	Antibody-Drug Conjugates (ADCs)	Cancer
Sofituzumab vedotin (DMUC5754A) is a MMAE-containing anti-MUC16 antibody-drug conjugate (ADC) with a protease-cleavable linker. Sofituzumab vedotin can be used for the research of cancer.

HY-130971

Mal-PEG4-bis-PEG3-DBCO
ADC Linker Cancer

Mal-PEG4-bis-PEG3-DBCO is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138780

Thalidomide-Piperazine-PEG3-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-Piperazine-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-150402

MC-Gly-Gly-Phe-Gly-amide-cyclopropanol-amide-Exatecan	Drug-Linker Conjugates for ADC	Cancer
MC-Gly-Gly-Phe-Gly-amide-cyclopropanol-amide-Exatecan is a pharmaceutical composition containing antibody drug conjugate (ADC). (extracted from patent WO2021190581 Example 1-8).

HY-130943

Methyltetrazine-PEG4-SS-PEG4-methyltetrazine	ADC Linker	Cancer
Methyltetrazine-PEG4-SS-PEG4-methyltetrazine is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-140111

Propargyl-PEG1-SS-PEG1-propargyl
ADC Linker Cancer

Propargyl-PEG1-SS-PEG1-propargyl is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-128907

MC-Val-Cit-PAB-clindamycin	Drug-Linker Conjugates for ADC	Cancer
MC-Val-Cit-PAB-clindamycin is a *drug-linker conjugate* for ADC** with potent antitumor activity by using clindamycin (a protein synthesis inhibitor), linked via the ADC linker MC-Val-Cit-PAB.

HY-130970

Amino-PEG4-bis-PEG3-methyltetrazine	ADC Linker	Cancer
Amino-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-141010A

Thalidomide-O-PEG4-amine hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-PEG4-amine hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-126527

N3-PEG2-C2-PFP ester
ADC Linker Cancer

N3-PEG2-C2-PFP ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-128957

Vc-seco-DUBA SYD985	Drug-Linker Conjugates for ADC	Cancer
Vc-seco-DUBA (SYD985) is a *drug-linker conjugate* for ADC** with potent antitumor activity by using DUBA (DNA alkylating agent), linked via the ADC linker Vc-seco.

HY-130950

Thalidomide-O-C4-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-128968

PEG4-aminooxy-MMAF	Microtubule/Tubulin Drug-Linker Conjugates for ADC	Cancer Inflammation/Immunology
PEG4-aminooxy-MMAF is a *drug-linker conjugate* for ADC** with potent antitumor activity by using the potent antitubulin agent MMAF, linked via the noncleavable PEG4.

HY-144880

SC209	ADC Cytotoxin EGFR Drug Metabolite	Cancer
SC209, an ADC cytotoxin extracted from patent WO2021247798, is used in synthesis of anti-EGFR antibody-drug conjugate ADC. SC209 is a metabolite of STRO-002.

HY-128902

MC-Val-Cit-PAB-vinblastine	Drug-Linker Conjugates for ADC	Cancer
MC-Val-Cit-PAB-vinblastine is a *drug-linker conjugate* for ADC** with potent antitumor activity by using vinblastine (an microtubule protein inhibitor), linked via the ADC linker MC-Val-Cit-PAB.

HY-130953

Mal-PEG4-bis-PEG3-methyltetrazine
ADC Linker Cancer

Mal-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138777

Thalidomide-Propargyne-PEG2-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-Propargyne-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-136089

Aminooxy-PEG2-bis-PEG3-BCN
ADC Linker Cancer

Aminooxy-PEG2-bis-PEG3-BCN is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140110

Propargyl-PEG1-SS-PEG1-PFP ester
ADC Linker Cancer

Propargyl-PEG1-SS-PEG1-PFP ester is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-126528

N3-PEG3-C2-NHS ester
ADC Linker Cancer

N3-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138772

Thalidomide-NH-PEG2-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-N1424S

Glycoursodeoxycholic Acid-d4	Endogenous Metabolite	Neurological Disease
Glycoursodeoxycholic acid-d4 (Ursodeoxycholylglycine-d4) is the deuterium labeled Glycoursodeoxycholic acid. Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid[1][2].

HY-19811

Fmoc-Val-Cit-PAB-MMAE	Drug-Linker Conjugates for ADC Microtubule/Tubulin	Cancer
Fmoc-Val-Cit-PAB-MMAE consists the ADCs linker (Fmoc-Val-Cit-PAB) and potent tubulin inhibitor (MMAE). Fmoc-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC.

HY-126491

SPP-DM1	Drug-Linker Conjugates for ADC	Cancer
SPP-DM1 is a *drug-linker conjugate* for ADC** with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker SPP.

HY-126526

N3-PEG2-C2-NHS ester
ADC Linker Cancer

N3-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-111859

SNIPER(ABL)-058	SNIPERs Bcr-Abl	Cancer
SNIPER(ABL)-058, conjugating Imatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC₅₀ of 10 μM.

HY-140634

Ald-CH2-PEG5-azide
ADC Linker Cancer

Ald-CH2-PEG5-azide is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-140133

PC-Biotin-PEG4-PEG3-azide
ADC Linker Cancer

PC-Biotin-PEG4-PEG3-azide is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130951

Thalidomide-O-C6-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C6-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-145365

DGN549-L	Drug-Linker Conjugates for ADC	Cancer
DGN549-L is a DNA alkylator and can be utilized for antibody conjugation at lysine residues. DGN549-L can be used in the synthesis of antibody-drug conjugates (ADCs).

HY-141887

Thalidomide-O-C6-NHBoc	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C6-NHBoc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-W034918

Docosanedioic acid	ADC Linker PROTAC Linkers	Cancer
Docosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Docosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-128961

MC-Alkyl-Hydrazine Modified MMAF	Drug-Linker Conjugates for ADC	Cancer
MC-Alkyl-Hydrazine Modified MMAF is a *drug-linker conjugate* for ADC** with potent antitumor activity by using the Modified MMAF (a tubulin inhibitor), linked via the noncleavable MC-Alkyl-Hydrazine.

HY-136060

Mal-PEG2-bis-PEG3-BCN
ADC Linker Cancer

Mal-PEG2-bis-PEG3-BCN is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-111854

SNIPER(ABL)-015	SNIPERs Bcr-Abl	Cancer
SNIPER(ABL)-015, conjugating GNF5 (ABL inhibitor) to MV-1 (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC₅₀ of 5 μM .

HY-138781

Thalidomide-Piperazine-PEG2-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-Piperazine-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-136318

β-D-tetraacetylgalactopyranoside-PEG1-N3	ADC Linker	Cancer
β-D-tetraacetylgalactopyranoside-PEG1-N3 is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130109

N3-PEG4-C2-NHS ester
ADC Linker Cancer

N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-101150

DGN462	DNA Alkylator/Crosslinker ADC Cytotoxin	Cancer
DGN462, a potent DNA-alkylating agent, shows anti-tumor activity, such as acute myeloid leukemia (AML). DGN462 can be used as a cytotoxic component of antibody-drug conjugates (ADCs).

HY-132208

Pomalidomide 4'-PEG2-azide	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide 4'-PEG2-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-138784

Thalidomide-PEG5-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-PEG5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-W040135

Fmoc-NH-PEG8-CH2CH2COOH
ADC Linker PROTAC Linkers Cancer

Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-128880

(+)-CBI-CDPI1	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
(+)-CBI-CDPI1 is an enhanced functional analog of CC-1065. (+)-CBI-CDPI1 is a DNA alkylating agent. (+)-CBI-CDPI1 is an antibody drug conjugates (ADCs) toxin.

HY-N1420

Rhamnose L-Rhamnose	Endogenous Metabolite	Cancer
Rhamnose (L-Rhamnose) is a monosaccharide found in plants and bacteria. Rhamnose-conjugated immunogens is used in immunotherapies. Rhamnose crosses the epithelia via the transcellular pathway and acts as a marker of intestinal absorption.

HY-136289

MB-VC-MGBA	Drug-Linker Conjugates for ADC	Cancer
MB-VC-MGBA is a drug-linker conjugate for ADC with potent antitumor activity by using MGBA (minor-groove-binding DNA-alkylating agent), linked via the ADC linker MB-VC.

HY-130965

Thalidomide-PEG3-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-133574

Mal-amido-PEG3-C1-PFP ester
ADC Linker Cancer

Mal-amido-PEG3-C1-PFP ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-128903

MC-Val-Cit-PAB-carfilzomib iodide	Drug-Linker Conjugates for ADC	Cancer
MC-Val-Cit-PAB-carfilzomib iodide is a *drug-linker conjugate* for ADC** with potent antitumor activity by using carfilzomib (an irreversible proteasome inhibitor), linked via the ADC linker MC-Val-Cit-PAB.

HY-138784A

Thalidomide-PEG5-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-PEG5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-133433

DBCO-PEG4-VA-PBD	Drug-Linker Conjugates for ADC	Cancer
DBCO-PEG4-VA-PBD is a drug-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via DBCO-PEG4-VA.

HY-131888A

Pomalidomide-C3-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-130929

β-Estradiol-6-CMO-PEG3-biotin
ADC Linker Cancer

β-Estradiol-6-CMO-PEG3-biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-141010B

Thalidomide-O-PEG4-amine TFA	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-PEG4-amine TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-136316

MC-VC-PAB-MMAD	Microtubule/Tubulin Drug-Linker Conjugates for ADC	Cancer
MC-VC-PAB-MMAD is a *drug-linker conjugate* for ADC** with potent antitumor activity by using MMAD (a potent tubulin inhibitor), linked via the cleavable ADC linker MC-VC-PAB.

HY-116374A

Glycolithocholic acid sodium Lithocholylglycine sodium	Others	Metabolic Disease
Glycolithocholic acid (Lithocholylglycine) sodium is the sodium salt of Glycolithocholic acid. Glycolithocholic acid is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC).

HY-152861

Dazostinag TAK-676 free base	STING	Cancer
Dazostinag (TAK-676 free base) is an agonist of stimulator of interferon genes (STING) protein with antineoplastic activity. Dazostinag can serve as a playload to synthesis *Antibody-Drug Conjugates* (ADCs)**.

HY-13631D

Dxd Exatecan derivative for ADC	Topoisomerase ADC Cytotoxin	Cancer
Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC₅₀ of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).

HY-W040246

Fmoc-NH-PEG6-CH2CH2COOH
ADC Linker PROTAC Linkers Cancer

Fmoc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-128881

(+)-CBI-CDPI2	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
(+)-CBI-CDPI2 is an enhanced functional analog of CC-1065. (+)-CBI-CDPI1 is a DNA alkylating agent. (+)-CBI-CDPI2 is an antibody drug conjugates (ADCs) toxin.

HY-130967

Ald-Ph-PEG4-bis-PEG4-propargyl
ADC Linker Cancer

Ald-Ph-PEG4-bis-PEG4-propargyl is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-12454S

DM4-d6	Microtubule/Tubulin ADC Cytotoxin	Cancer
DM4-d₆ is deuterium labeled DM4. DM4 is is an antitubulin agent that inhibit cell division. DM4 can be used in the preparation of antibody drug conjugate.

HY-147057A

FAP-2286 acetate	FAP	Cancer
FAP-2286 acetate is the conjugate of a fibroblast activation protein (FAP)-binding peptide. FAP-2286 acetate can be labeled with radionuclides for theranostic applications. FAP-2286 acetate has antitumor activity.

HY-130974

Ald-Ph-PEG4-bis-PEG3-methyltetrazine	ADC Linker	Cancer
Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-141091

Biotin-PEG4-Dde-TAMRA-PEG3-Azide
ADC Linker Cancer

Biotin-PEG4-Dde-TAMRA-PEG3-Azide is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-147021A

MC-D-Val-Cit-PAB-PNP	ADC Linker	Cancer Infection Inflammation/Immunology
MC-D-Val-Cit-PAB-PNP is a drug-linker-ligand conjugates. MC-D-Val-Cit-PAB-PNP can be used for researching cancer, autoimmune diseases and infectious diseases.

HY-130931

Propargyl-NH-PEG3-C2-NHS ester
ADC Linker Cancer

Propargyl-NH-PEG3-C2-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138845A

Pomalidomide-C4-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-130964B

Thalidomide-PEG4-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-136315

OSu-Glu-VC-PAB-MMAD	Microtubule/Tubulin Drug-Linker Conjugates for ADC	Cancer
OSu-Glu-VC-PAB-MMAD is a *drug-linker conjugate* for ADC** with potent antitumor activity by using MMAD (a potent tubulin inhibitor), linked via the cleavable ADC linker OSu-Glu-VC-PAB.

HY-15944

5(6)-TAMRA 5(6)-Carboxytetramethylrhodamine	Fluorescent Dye	Others
5(6)-TAMRA contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; bright, orange-fluorescent dye produces conjugates with absorption/emission maxima of ~555/580 nm.

HY-128955

MC-VC-PABC-Aur0101	Drug-Linker Conjugates for ADC	Cancer
MC-VC-PABC-Aur0101 is a *drug-linker conjugate* for ADC** with potent antitumor activity by using Aur0101 (an auristatin microtubule inhibitor), linked via the ADC linker MC-VC-PABC.

HY-130083

Seco-Duocarmycin TM	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
Seco-Duocarmycin TM is a DNA alkylator agent belonging to Duocarmycins family that inhibits DNA synthesis. Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates (ADC)^[1].

HY-D1239

BODIPY R6G NHS ester	Fluorescent Dye	Others
BODIPY R6G NHS ester is a borondipyrromethene dye. BODIPY R6G NHS ester can be conjugated with proteins. BODIPY R6G NHS ester can be used for intracellular traces.

HY-132600

RG-101 Temavirsen	MicroRNA	Infection
RG-101 is a hepatocyte targeted N-acetylgalactosamine conjugated oligonucleotide that antagonises miR-122. miR-122 is an important host factor for hepatitis C virus (HCV) replication.

HY-111873

SNIPER(ABL)-019	SNIPERs Bcr-Abl	Cancer
SNIPER(ABL)-019, conjugating Dasatinib (ABL inhibitor) to MV-1 (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC₅₀ of 0.3 μM.

HY-128893

MC-Sq-Cit-PAB-Gefitinib	Drug-Linker Conjugates for ADC	Cancer
MC-Sq-Cit-PAB-Gefitinib is a *drug-linker conjugate* for ADC** with potent antitumor activity by using Gefitinib (an EGFR tyrosine kinase inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.

HY-133539

Propargyl-C8-amido-PEG2-NHS ester	ADC Linker	Cancer
Propargyl-C8-amido-PEG2-NHS ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133484

Thalidomide-PEG2-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-133582

Mal-amido-PEG3-C1-NHS ester
ADC Linker Cancer

Mal-amido-PEG3-C1-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-109539

Gemtuzumab ozogamicin	Antibody-Drug Conjugates (ADCs)	Cancer
Gemtuzumab ozogamicin is an antibody-drug conjugate (ADC) consisting of a monoclonal antibody targeting CD33 linked to a cytotoxic derivative of Calicheamicin. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia.

HY-D0980

Biotin-DADOO Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin	Biochemical Assay Reagents	Metabolic Disease
Biotin-DADOO is a biotinylation reagent, which can be used to synthesize a biotin-estradiol conjugate (i.e., biotin-DADOO-estradiol) to develop a direct, broad range enzyme immunoassay to measure plasma estradiol concentrations.

HY-133492

DBCO-PEG4-MMAF	Drug-Linker Conjugates for ADC	Cancer
DBCO-PEG4-MMAF is a drug-linker conjugate for ADC with potent antitumor activity by using the tubulin polymerization inhibitor, MMAF, linked via the cleavable linker DBCO-PEG4.

HY-130546

Hydroxy-PEG3-SS-PEG3-alcohol
ADC Linker Cancer

Hydroxy-PEG3-SS-PEG3-alcohol is also a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138845

Pomalidomide-C4-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-131888

Pomalidomide-C3-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-133816A

Pomalidomide-amino-PEG5-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-amino-PEG5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-W125504

AEEA-AEEA	ADC Linker PROTAC Linkers	Cancer
AEEA-AEEA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). AEEA-AEEA is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-128908

MC-Val-Cit-PAB-Indibulin	Drug-Linker Conjugates for ADC	Cancer
MC-Val-Cit-PAB-Indibulin is a *drug-linker conjugate* for ADC** with potent antitumor activity by using Indibulin (an orally applicable inhibitor of tubulin assembly), linked via the ADC linker MC-Val-Cit-PAB.

HY-136162A

Thalidomide 4'-ether-alkylC2-amine	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide 4'-ether-alkylC2-amine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-128899

MC-Val-Cit-PAB-Auristatin E	Drug-Linker Conjugates for ADC	Cancer
MC-Val-Cit-PAB-Auristatin E is a *drug-linker conjugate* for ADC** with potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker MC-Val-Cit-PAB.

HY-133485B

Thalidomide-O-C8-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C8-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-111861

SNIPER(ABL)-024	SNIPERs Bcr-Abl	Cancer
SNIPER(ABL)-024, conjugating GNF5 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC₅₀ of 5μM.

HY-17640

Nicodicosapent	Fatty Acid Synthase (FASN) Autophagy	Metabolic Disease
Nicodicosapent is a fatty acid niacin conjugate that is also an inhibitor of the sterol regulatory element binding protein (SREBP), a key regulator of cholesterol metabolism proteins such as PCSK9, HMG-CoA reductase, ATP citrate lyase, and NPC1L1.

HY-126492

Vat-Cit-PAB-Monomethyl Dolastatin 10	Drug-Linker Conjugates for ADC	Cancer
Vat-Cit-PAB-Monomethyl Dolastatin 10 is a *drug-linker conjugate* for ADC** with potent antitumor activity by using Monomethyl Dolastatin 10 (a potent tubulin inhibitor), linked via the ADC linker Vat-Cit-PAB.

HY-138847

Thalidomide-O-C3-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-133817

Pomalidomide-amino-PEG3-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-amino-PEG3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-130818

N-(5-Hydroxypentyl)maleimide	ADC Linker	Cancer
N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812) ).

HY-130949

Thalidomide-O-C7-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C7-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-138858A

Thalidomide-amido-PEG2-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-amido-PEG2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-134986

Thalidomide-NH-C5-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-C5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-138848A

Thalidomide-O-C5-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-133817A

Pomalidomide-amino-PEG3-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-amino-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-P99712

Lonigutamab hz208F2-4	IGF-1R ADC Antibody	Cancer
Lonigutamab (hz208F2-4) is a humanized anti-IGF-1R monoclonal antibody that can be used for the synthesis of antibody–drug conjugates (ADC).

HY-130948

Thalidomide-O-C4-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-148773

MC-Gly-Gly-Phe-Boc	ADC Linker	Cancer
MC-Gly-Gly-Phe-Boc is involved in the synthesis of *Antibody-Drug Conjugates* (ADCs)** to Trastuzumab (HY-P9907). MC-Gly-Gly-Phe-Boc can participate in cancer research.

HY-138787

Thalidomide-Piperazine-PEG3-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-Piperazine-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-128897

MC-VC-PABC-DNA31	Drug-Linker Conjugates for ADC	Cancer
MC-VC-PABC-DNA31 is a *drug-linker conjugate* for ADC** with potent antitumor activity by using DNA31 (a potent RNA polymerase inhibitor), linked via the ADC linker MC-VC-PABC.

HY-133816

Pomalidomide-amino-PEG5-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-amino-PEG5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-138859

Pomalidomide-amino-PEG4-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-amino-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-131867

Thalidomide-NH-PEG1-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-PEG1-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-N1420A

Rhamnose monohydrate L-Rhamnose monohydrate	Endogenous Metabolite	Cancer
Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies. Rhamnose monohydrate crosses the epithelia via the transcellular pathway and acts as a marker of intestinal absorption.

HY-138789

Thalidomide-Piperazine-PEG1-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-Piperazine-PEG1-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-111862

SNIPER(ABL)-044	SNIPERs Bcr-Abl	Cancer
SNIPER(ABL)-044, conjugating HG-7-85-01 (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC₅₀ of 10 μM.

HY-138848

Thalidomide-O-C5-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-130978

Duocarmycin DM	DNA Alkylator/Crosslinker ADC Cytotoxin	Cancer
Duocarmycin DM, a DNA minor-groove alkylator, is an antibody drug conjugates (ADCs) toxin. Duocarmycin DM is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity.

HY-138846A

Thalidomide-NH-C8-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-C8-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-D0024

Sudan I Solvent Yellow 14	Bacterial	Others
Sudan I (Solvent Yellow 14) is a diazo-conjugate red dye and can be used as an additive to products such as oils, solvents or polishes. Sudan I inhibits growth of bacterial strains Clostridium perfringens and L. rhamnosus.

HY-151752

Mal-AMCHC-N-Propargylamide	ADC Linker	Others
Mal-AMCHC-N-Propargylamide is a click chemistry reagent containing an azide group. Mal-AMCHC-N-Propargylamide can be a bio-conjugation reagent for antibody-drug-conjugate synthesis using Click-Chemistry.

HY-138858

Thalidomide-amido-PEG2-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-amido-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-136237

Thalidomide-NH-C5-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-C5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-130963

Thalidomide-O-C10-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-138847A

Thalidomide-O-C3-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-117050

PEG12-Tos	ADC Linker PROTAC Linkers	Cancer
Tos-PEG12 is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). PEG12-Tos is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-129704B

Thalidomide-NH-C6-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-135250

Thalidomide-O-C6-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C6-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-44149

m-C-tri(CH2-PEG1-NHS ester)
ADC Linker Cancer

m-C-tri(CH2-PEG1-NHS ester) is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138846

Thalidomide-NH-C8-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-133485

Thalidomide-O-C8-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-134985

Thalidomide-NH-PEG1-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-PEG1-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-129704

Thalidomide-NH-C6-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-C6-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-136162

Thalidomide 4'-ether-alkylC2-amine hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide 4'-ether-alkylC2-amine hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-138788

Thalidomide-Piperazine-PEG2-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-Piperazine-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-129832

Biotin-azide N-(3-Azidopropyl)biotinamide	Biochemical Assay Reagents	Others
Biotin-azide (N-(3-Azidopropyl)biotinamide) is a form of biotin with a terminal azide group. Biotin-azide can be used to prepare various biotinylated conjugates via Click Chemistry.

HY-136090

Amino-PEG4-bis-PEG3-N3
ADC Linker Cancer

Amino-PEG4-bis-PEG3-N3 is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-141597

Acid-C3-SSPy
ADC Linker Cancer

Acid-C3-SSPy is a cleavable DBA-DM4 linker used in the synthesis of DBA-DM4 (HY-128960), a drug-linker conjugate for ADC.

HY-128909

MC-Val-Cit-PAB-rifabutin	Drug-Linker Conjugates for ADC	Cancer
MC-Val-Cit-PAB-rifabutin is a *drug-linker conjugate* for ADC** with potent antitumor activity by using rifabutin (an DNA-dependent RNA polymerase inhibitor), linked via the ADC linker MC-Val-Cit-PAB.

HY-135868

Mito-apocynin (C2)	Mitochondrial Metabolism	Neurological Disease
Mito-apocynin (C2), an orally active mitochondria-targeted triphenylphosphonium (TPP)-based compound, is synthesized by conjugating the Apocynin moiety with a TPP ⁺ cation. Mito-apocynin (C2) exhibits antineuroinflammatory effect.

HY-145449

CC-885-CH2-PEG1-NH-CH3
ADC Cytotoxin PROTACs Cancer

CC-885-CH2-PEG1-NH-CH3 is a neoDegrader that can be used in the synthesis of Antibody neoDegrader Conjugate (AnDC).
HY-131990

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
ADC Linker Cancer

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138859A

Pomalidomide-amino-PEG4-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-amino-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-136320

MC-VC-PABC-SP 141	Drug-Linker Conjugates for ADC MDM-2/p53	Cancer
MC-VC-PABC-SP 141 is a *drug-linker conjugate* for ADC** with potent antitumor activity by using SP 141 (a potent MDM2 inhibitor), linked via the cleavable ADC linker MC-VC-PABC.

HY-150158

TMX-201	Toll-like Receptor (TLR)	Cancer
TMX-201 is a TLR7 ligand-phospholipid conjugate. TMX-201 shows potent immune stimulatory activity. TMX-201 can be used for breast cancer and melanoma research.

HY-128946

CL2A-SN-38	Drug-Linker Conjugates for ADC	Cancer Inflammation/Immunology
CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A-SN-38 uses hydrolyzable linker to deliver active drugs within tumor cells and in the tumor microenvironment, resulting in bystander effects.

HY-139066

Punicic acid Trichosanic acid	Others	Metabolic Disease
Punicic acid is a bioactive compound of pomegranate seed oil. Punicic acid is an isomer of conjugated α-linolenic acid and a ω-5 polyunsaturated fatty acid. Punicic acid has the potential for the research of various chronic diseases.

HY-116374

Glycolithocholic acid Lithocholylglycine	Endogenous Metabolite	Inflammation/Immunology
Glycolithocholic acid (Lithocholylglycine), an endogenous metabolite, is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC).

HY-148127

TAM558	Drug-Linker Conjugates for ADC	Cancer
TAM558 is a payload molecule used for the synthesis of OMTX705. OMTX705 is a humanized anti-fibroblast-activating protein (FAP) antibody conjugated to the cytolysin TAM470 (HY-148128), with antitumor activity.

HY-128938

EC1167	ADC Linker	Cancer
EC1167 is the linker for EC1169. EC1169 is prostate-specific membrane antigen targeting-tubulysin conjugate. EC1169 has the potential to treat recurrent metastatic, castration-resistant prostate cancer (MCRPC).

HY-126682

Mal-VC-PAB-DM1	Drug-Linker Conjugates for ADC	Cancer
Mal-VC-PAB-DM1 is a *drug-linker conjugate* for ADC** with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker Mal-VC-PAB .

HY-76043

H-Hyp-OMe hydrochloride	ADC Linker PROTAC Linkers	Cancer
H-Hyp-OMe hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). H-Hyp-OMe hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs^[1]<

HY-138853

Thalidomide-NH-amido-C8-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-amido-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-W010975

Fmoc-Lys-OH hydrochloride	ADC Linker PROTAC Linkers	Cancer
Fmoc-Lys-OH hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Lys-OH hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-126693

SC-VC-PAB-DM1	Drug-Linker Conjugates for ADC	Cancer
SC-VC-PAB-DM1 is a *drug-linker conjugate* for ADC** with with potent antitumor activity by using DM1 (Mertansine, a tubulin inhibitor) , linked via the ADC linker SC-VC-PAB.

HY-137538

Pomalidomide-PEG3-azide	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

HY-138789A

Thalidomide-Piperazine-PEG1-NH2 diTFA	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-Piperazine-PEG1-NH2 diTFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-138849A

Thalidomide-NH-amido-C2-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-amido-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-110213

BODIPY 630/650X	Fluorescent Dye	Others
BODIPY 630/650X is a fluorescent conjugate of the adenosine receptor ligand N-ethylcarboxamido-adenosine (NECA). BODIPY 630/650X displays excitation/emission maxima of 630/650 nm, respectively.

HY-128904

MC-Val-Cit-PAB-duocarmycin chloride	Drug-Linker Conjugates for ADC	Cancer
MC-Val-Cit-PAB-duocarmycin chloride is a *drug-linker conjugate* for ADC** with potent antitumor activity by using Duocarmycin (a DNA minor groove binding alkylating agent), linked via the ADC linker MC-Val-Cit-PAB.

HY-108379

Boc-C2-Urea-bis(Boc)-C4-Urea-4-phenylacetic acid	ADC Linker	Cancer
Boc-C2-Urea-bis(Boc)-C4-Urea-4-phenylacetic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-129704A

Thalidomide-NH-C6-NH2 TFA	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-134984A

Thalidomide-NH-amido-C4-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-amido-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-151645

Alkyne-SNAP	ADC Linker	Others
Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation.

HY-107093

MBC-11	Others	Cancer
MBC-11 is a first-in-class conjugate of the bone-targeting bisphosphonate etidronate covalently linked to the antimetabolite cytarabine (araC). MBC-11 has the potential for tumor-induced bone disease (TIBD) research.

HY-134984

Thalidomide-NH-amido-C4-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-amido-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-138850A

Thalidomide-NH-amido-C3-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-amido-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-P1043A

NGR peptide Trifluoroacetate	Aminopeptidase	Cancer
NGR peptide Trifluoroacetatecontaining the Asn-Gly-Arg (NGR) motif. NGR peptide Trifluoroacetate binds to APN/CD13. NGR peptide Trifluoroacetate is directly conjugated to imaging agents that can be used for tumor imaging.

HY-140101

Azido-C2-SS-PEG2-C2-acid
ADC Linker Cancer

Azido-C2-SS-PEG2-C2-acid is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-151764

N3-D-Orn(Boc)-OH	ADC Linker	Others
N3-D-Orn(Boc)-OH is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC).

HY-138850

Thalidomide-NH-amido-C3-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-amido-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-128894

MC-Sq-Cit-PAB-Dolastatin10	Drug-Linker Conjugates for ADC	Cancer
MC-Sq-Cit-PAB-Dolastatin10 is a *drug-linker conjugate* for ADC** with potent antitumor activity by using Dolastatin10 (a tubulin polymerization inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.

HY-138851

Thalidomide-NH-amido-C5-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-amido-C5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-131998

Thalidomide-NH-PEG4-Ms	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-PEG4-Ms is an E3 ligase ligand-linker conjugate that incorporates Thalidomide based cereblon ligand and a linker used for PROTAC BCL-XL degrader XZ739.

HY-138852

Thalidomide-NH-amido-C6-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-amido-C6-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-136161

Pomalidomide-PEG6-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 6-unit PEG linker used in PROTAC technology.

HY-128938A

EC1167 hydrochloride	ADC Linker	Cancer
EC1167 hydrochloride is the linker for EC1169. EC1169 is prostate-specific membrane antigen targeting-tubulysin conjugate. EC1169 hydrochloride has the potential to treat recurrent metastatic, castration-resistant prostate cancer (MCRPC).

HY-130639

Thalidomide-NH-C4-NH-Boc	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-C4-NH-Boc (compound 15) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-137537

Pomalidomide-PEG2-azide	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG2-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.

HY-P1043

NGR peptide	Aminopeptidase	Cancer
NGR peptide containing the Asn-Gly-Arg (NGR) motif. NGR peptide binds to APN/CD13. NGR peptide is directly conjugated to imaging agents that can be used for tumor imaging.

HY-138853A

Thalidomide-NH-amido-C8-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-amido-C8-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-W016429

H-cis-Hyp-OMe hydrochloride	ADC Linker PROTAC Linkers	Cancer
H-cis-Hyp-OMe hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). H-cis-Hyp-OMe hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PR

HY-128767

VH032-PEG3-acetylene	E3 Ligase Ligand-Linker Conjugates	Cancer
VH032-PEG3-acetylene is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology.

HY-41541

Tetraethylene glycol monotosylate Tos-PEG4	ADC Linker PROTAC Linkers	Cancer
Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tetraethylene glycol monotosylate also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.

HY-131085

Desmethyl Vc-seco-DUBA	Drug-Linker Conjugates for ADC	Cancer
Desmethyl Vc-seco-DUBA consists a cleavable ADC linker (Desmethyl Vc-seco) and a DNA alkylating agent (DUBA). Desmethyl Vc-seco-DUBA can be used in the synthesis of antibody-drug conjugates (ADCs).

HY-130957

Amino-PEG6-amido-bis-PEG5-N3
ADC Linker Cancer

Amino-PEG6-amido-bis-PEG5-N3 is a cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-138851A

Thalidomide-NH-amido-C5-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-amido-C5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-141423

Thalidomide-O-amide-C5-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amide-C5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-138849

Thalidomide-NH-amido-C2-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-amido-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-130969

Ald-Ph-PEG4-bis-PEG3-N3
ADC Linker Cancer

Ald-Ph-PEG4-bis-PEG3-N3 is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-P99854

Disitamab RC48-0	EGFR ADC Antibody	Cancer
Disitamab (RC48-0) is a humanized monoclonal antibody targeting HER2. Disitamab can be used in the synthesis of antibody-drug conjugates (ADCs), Disitamab vedotin (Disitamab vedotin (HY-P9985)).

HY-138852A

Thalidomide-NH-amido-C6-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-amido-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-138788A

Thalidomide-Piperazine-PEG2-NH2 diTFA	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-Piperazine-PEG2-NH2 diTFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-138786

Thalidomide-5-PEG3-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-5-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-126671

Mal-Phe-C4-Val-Cit-PAB	ADC Linker	Cancer
Mal-Phe-C4-Val-Cit-PAB is a cleavable ADC linker containing a Maleimide group. Mal-Phe-C4-Val-Cit-PAB is used for making antibody-drug conjugate.

HY-107438A

Thalidomide-O-amido-C4-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amido-C4-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.

HY-15579A

MMAF hydrochloride Monomethylauristatin F hydrochloride	Microtubule/Tubulin ADC Cytotoxin	Cancer
MMAF (Monomethylauristatin F) hydrochloride is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF hydrochloride is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A.

HY-133546

Ald-Ph-amido-PEG11-C2-NH2
ADC Linker Cancer

Ald-Ph-amido-PEG11-C2-NH2 is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W017755

(R)-Azetidine-2-carboxylic acid	ADC Linker PROTAC Linkers	Cancer
(R)-Azetidine-2-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). (R)-Azetidine-2-carboxylic acid is also a alkyl chain-based PROTAC linker that can be

HY-136166

Thalidomide-NH-PEG3-propionic acid	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

HY-151764A

N3-D-Orn(Boc)-OH (CHA)	ADC Linker	Others
N3-D-Orn(Boc)-OH (CHA) is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC).

HY-65039

Boc-Hyp-OMe	ADC Linker PROTAC Linkers	Cancer
Boc-Hyp-OMe is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OMe is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-140242

NH2-PEG4-Lys(Boc)-NH-(m-PEG24)
ADC Linker Cancer

NH2-PEG4-Lys(Boc)-NH-(m-PEG24) is a cleavable 28 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-136084

Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO)
ADC Linker Cancer

Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO) is a cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130948B

Thalidomide-O-C4-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates
Thalidomide-O-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide (HY-14658) based cereblon ligand and a linker used in PROTAC technology.

HY-107439A

Thalidomide-O-amido-C8-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amido-C8-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.

HY-136130

N,N-Bis(PEG2-alkyne)-N-amido-PEG2-thiol	ADC Linker	Cancer
N,N-Bis(PEG2-alkyne)-N-amido-PEG2-thiol is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-111863

SNIPER(ABL)-047	SNIPERs Bcr-Abl	Cancer
SNIPER(ABL)-047, conjugating HG-7-85-01 (ABL inhibitor) to MV-1 (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC₅₀ of 2 μM.

HY-15301

CC0651	E1/E2/E3 Enzyme	Cancer
CC0651 is an allosteric inhibitor of the human *Cdc34 ubiquitin-conjugating* enzyme. CC0651 potently (IC₅₀**=1.72 μM) inhibits the ubiquitination of p27^Kip1, as confirmed by dose-response analysis.

HY-136156

Pomalidomide-PEG6-butyl iodide	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG6-butyl iodide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 6-unit PEG linker used in PROTAC technology.

HY-112618B

Thalidomide-O-amido-C6-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amido-C6-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.

HY-122694

Thalidomide-O-amido-PEG-C2-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amido-PEG-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-D1707

FDGlcU	Fluorescent Dye	Others
FDGlcU can be used as a fluorescent probe for non-invasively image with a high level of fluorescent activity. FDGlcU is non-fluorescent when the fluorescein is conjugated with two mono-glucuronides (Ex/Em=480/514 nm).

HY-I0781

Boc-Hyp-OH	ADC Linker PROTAC Linkers	Cancer
Boc-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs^[2]

HY-138786A

Thalidomide-5-PEG3-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-5-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-141423A

Thalidomide-O-amide-C5-NH2 TFA	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amide-C5-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-138785A

Thalidomide-5-PEG4-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-5-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-W018154

H-Glu-OtBu	ADC Linker PROTAC Linkers	Cancer
H-Glu-OtBu is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). H-Glu-OtBu is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs^[2

HY-126886

Mal-PEG1-NHS ester	ADC Linker PROTAC Linkers	Cancer
Mal-PEG1-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG1-NHS ester is PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-138785

Thalidomide-5-PEG4-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-5-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-42972

DBCO-acid	ADC Linker	Cancer
DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and drug-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690).

HY-D1665

BDP 558/568 amine	Fluorescent Dye	Others
BDP 558/568 amine is an amine derivative of BDP 558/568. BDP 558/568 is a borondipyrromethene dye with yellow/orange emission. BDP 558/568 amine can be conjugated by means of reactions with various electrophiles.

HY-19796

Icomidocholic acid Aramchol; C20-FABAC	Stearoyl-CoA Desaturase (SCD)	Metabolic Disease
Icomidocholic acid (Aramchol) is a conjugate of cholic acid and arachidic acid that could inhibit stearoyl coenzyme A desaturase 1 (SCD1) activity. Icomidocholic acid has potential use in nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) treatment.

HY-P99565

Tengonermin ARENEGYR; NGR-TNF; NGR-hTNF	TNF Receptor	Cancer
Tengonermin (ARENEGYR) is a vascular-targeting agent consisting of the human Tumour Necrosis Factor-α (TNF-α) conjugated with the CNGRCG peptide. Tengonermin increases penetration of intratumoral chemotherapy and T-cell infiltration by modifying the tumour microenvironment.

HY-148668A

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan	Topoisomerase Drug-Linker Conjugates for ADC	Cancer
MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a *drug-linker conjugates* for ADC**, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC₅₀=2.2 μM).

HY-40144

Azetidin-3-ol hydrochloride	ADC Linker PROTAC Linkers	Cancer
Azetidin-3-ol hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azetidin-3-ol hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthes PROTAC.

HY-135250B

Thalidomide-O-C6-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12^F36V and BET.

HY-P99788

Praluzatamab	ADC Antibody ALCAM/CD166	Cancer
Praluzatamab is a monoclonal antibody targeting the activated leukocyte cell adhesion molecule (ALCAM/CD116). Praluzatamab can be used to synthesize Praluzatamab ravtansine (antibody-drug conjugates). Praluzatamab can be used for research of cancers.

HY-142740

Rha-PEG3-SMCC	Drug-Linker Conjugates for ADC	Cancer
Rha-PEG3-SMCC (compound 13) is a drug-linker conjugate for ADC* with potent antitumor activity by using SMCC (a* protein crosslinker), linked via the noncleavable ADC linker Rha-PEG3.

HY-153043

DM-CO-(CH2)5-SMe	Others	Cancer
DM-CO-(CH2)5-SMe is an anticancer agent derived from antibody-drug conjugates (ADC) metabolite with cytotoxicity to H1703, H1975, COLO704 and Colo720E cells.

HY-126681

SC-VC-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
SC-VC-PAB-MMAE is a *drug-linker conjugate* for ADC** with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker SC-VC-PAB.

HY-126668

Mal-PEG4-VC-PAB-DMEA	ADC Linker	Cancer
Mal-PEG4-VC-PAB-DMEA is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-VC-PAB-DMEA is used in the synthesis of antibody-drug conjugates (ADCs).

HY-117519A

Amino-Tri-(carboxyethoxymethyl)-methane hydrochloride	ADC Linker PROTAC Linkers	Cancer
Amino-Tri-(carboxyethoxymethyl)-methane hydrochloride is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(carboxyethoxymethyl)-methan hydrochloride is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-77641S

Cinnamoylglycine-d2	Endogenous Metabolite	Metabolic Disease
Cinnamoylglycine-d₂ is the deuterium labeled Cinnamoylglycine. Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine is used as a potential urinary biomarker indicating intact or disrupted colonization resistance during and after antibiotic treatment[1].

HY-153013

SN38-COOH	Drug-Linker Conjugates for ADC	Cancer
SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis.

HY-107093B

MBC-11 triethylamine	Others	Cancer
MBC-11 triethylamine is a first-in-class conjugate of the bone-targeting bisphosphonate etidronate covalently linked to the antimetabolite cytarabine (araC). MBC-11 triethylamine has the potential for tumor-induced bone disease (TIBD) research.

HY-126683

Mal-C6-α-Amanitin	Drug-Linker Conjugates for ADC	Cancer
Mal-C6-α-Amanitin is a *drug-linker conjugate* for ADC** with potent antitumor activity by using α-Amanitin (an RNA polymerase II inhibitor), linked via the ADC linker Mal-C6.

HY-P99630

Gancotamab MM-302	EGFR	Cancer
Gancotamab (MM-302) is a HER2-targeted antibody-liposomal Doxorubicin conjugate with antitumor activity. Gancotamab encapsulates Doxorubicin to facilitate its delivery to HER2-overexpressing tumor cells.

HY-121271

Kadsurin	Others	Inflammation/Immunology
Kadsurin, a natural compound from the stems of Kadsura heteroclita (Schizandraceae), results in significant decreases of CCL₄- induced lipid-peroxidation products, such as thiobarbituric acid reactive substances (TBA-RS), conjugated dienes and fluorescent products in the liver of mice.

HY-42745

m-PEG2-Tos	ADC Linker PROTAC Linkers	Cancer
m-PEG2-Tos is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG2-Tos is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-107093A

MBC-11 trisodium	Others	Cancer
MBC-11 trisodium is a first-in-class conjugate of the bone-targeting bisphosphonate HEDP covalently linked to the antimetabolite Ara-C. MBC-11 trisodium has the potential for tumor-induced bone disease (TIBD) research.

HY-126672

Mal-PEG4-Val-Cit-PAB	ADC Linker	Cancer
Mal-PEG4-Val-Cit-PAB is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-Val-Cit-PAB is used in the synthesis of antibody-drug conjugates (ADCs).

HY-79125

Fmoc-Hyp(Bom)-OH	ADC Linker PROTAC Linkers	Cancer
Fmoc-Hyp(Bom)-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Hyp(Bom)-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs<

HY-N6740

Beta-Zearalanol	Apoptosis	Metabolic Disease
Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells. Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid.

HY-122694A

Thalidomide-O-amido-PEG-C2-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.

HY-111871

SNIPER(ABL)-033	SNIPERs Bcr-Abl	Cancer
SNIPER(ABL)-033, conjugating HG-7-85-01 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC₅₀ of 0.3 μM.

HY-15575

VcMMAE MC-Val-Cit-PAB-MMAE; mc-vc-PAB-MMAE	Drug-Linker Conjugates for ADC Microtubule/Tubulin	Cancer
VcMMAE (mc-vc-PAB-MMAE) is a *drug-linker conjugate* for ADC** with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).

HY-148668

MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a *drug-linker conjugates* for ADC**, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC₅₀=2.2 μM).

HY-101884A

Biotinylated-D-lysine TFA	Others	Neurological Disease
Biotinylated-D-lysine TFA is a conjugate of _L-biotin and _D-lysine, where the carboxylate of _L-biotin is coupled with the ϵ-amine of _D-lysine via a secondary amide bond. Biotinylated-D-lysine TFA is an isomer of the neuroanatomical tracer Biocyte.

HY-126958

Biotin-PEG2-acid	PROTAC Linkers ADC Linker	Cancer Inflammation/Immunology
Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Biotin-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-126674

Mal-Phe-C4-Val-Cit-PAB-DMEA	ADC Linker	Cancer
Mal-Phe-C4-Val-Cit-PAB-DMEA is a cleavable ADC linker containing a Maleimide group. Mal-Phe-C4-Val-Cit-PAB-DMEA is used for making antibody-drug conjugate.

HY-130528

m-PEG7-Ms	ADC Linker PROTAC Linkers	Cancer
m-PEG7-Ms is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG7-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130716

Thalidomide-NH-C10-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-C10-COOH (compound 6b) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based von Hippel-Lindau (VHL) ligand and a linker used in PROTAC technology.

HY-15579B

MMAF sodium Monomethylauristatin F sodium	Microtubule/Tubulin ADC Cytotoxin	Cancer
MMAF sodium (Monomethylauristatin F sodium) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF sodium (Monomethylauristatin F sodium) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A.

HY-148131

MC-Val-Cit-PABA-amide-PEG4-COOH	ADC Linker	Cancer
MC-Val-Cit-PABA-amide-PEG4-COOH is a cleavable ADC linker used in the synthesis of OMTX705. OMTX705 is a novel FAP-targeting antibody-drug conjugates (ADCs), and shows antitumor activity.

HY-138862

(S,R,S)-AHPC-C1-Br	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C1-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology.

HY-41189

Fmoc-Val-Cit-PAB-PNP	ADC Linker	Cancer
Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Val-Cit-PAB-PNP has superior plasma stability comparable to that of non-cleavable linkers.

HY-148871

Mc-Val-Cit-PAB-Gefitinib chloride	Drug-Linker Conjugates for ADC	Cancer
Mc-Val-Cit-PAB-Gefitinib chloride is a *drug-linker conjugates* for ADC. Mc-Val-Cit-PAB-Gefitinib chloride consists of Gefitinib (HY-50895) (an EGFR** tyrosine kinase inhibitor) and the ADC linker Mc-Val-Cit-PAB.

HY-130475

Azido-PEG9-acid	PROTAC Linkers ADC Linker	Cancer Inflammation/Immunology
Azido-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-132142

5-Propargylamino-dCTP	DNA/RNA Synthesis	Others
5-Propargylamino-dCTP is a nucleoside molecule extracted from patent US9035035B2, compound dCTP-PA. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis.

HY-126673

Mal-C2-Gly3-EDA
ADC Linker Cancer

Mal-C2-Gly3-EDA is a cleavable ADC linker containing a Maleimide group. Mal-C2-Gly3-EDA is used for making antibody-drug conjugate.

HY-136297

DGN549-C	Drug-Linker Conjugates for ADC	Cancer
DGN549-C consists a cleavable ADC linker valine-alanine (va) and PBD dimer. DGN549 is a novel DNA-alkylating cytotoxic payload and can be used in the synthesis of antibody-drug conjugates (ADCs).

HY-117519

Amino-Tri-(carboxyethoxymethyl)-methane	ADC Linker PROTAC Linkers	Cancer
Amino-Tri-(carboxyethoxymethyl)-methane is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(carboxyethoxymethyl)-methan is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-15579

MMAF Monomethylauristatin F	Microtubule/Tubulin ADC Cytotoxin	Cancer
MMAF (Monomethylauristatin F) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF (Monomethylauristatin F) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as vorsetuzumab mafodotin and SGN-CD19A.

HY-136163A

(S,R,S)-AHPC-C2-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology.

HY-P99817

Pegaldesleukin	Interleukin Related HIV	Infection
Pegaldesleukin is a conjugate of polyethylene glycol and interleukin-2 (PEG-IL2). Pegaldeslukin has antiviral activity and has potential applications in HIV, possibly delaying the progression of HIV infection by retaining the immune repertoire.

HY-131833A

Fmoc-Gly-Gly-D-Phe-OH	ADC Linker	Cancer
Fmoc-Gly-Gly-D-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Gly-Gly-D-Phe-OH is the D-isomer of Fmoc-Gly-Gly-Phe-OH (HY-131833).

HY-132603

AB-729	Small Interfering RNA (siRNA) HBV	Infection
AB-729 is a siRNA specifically designed to inhibit viral replication and reduces HBV antigens. AB-729 conjugates to a trimer of N-acetylgalactosamine (GalNAc) ligand that promotes uptake into hepatocytes via the asialoglycoprotein receptor (ASGR).

HY-133583

Propargyl-O-C1-amido-PEG3-C2-NHS ester	ADC Linker	Cancer
Propargyl-O-C1-amido-PEG3-C2-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-141379

N-Bromoacetyl-β-alanine	PROTAC Linkers ADC Linker	Cancer
N-Bromoacetyl-β-alanine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. N-Bromoacetyl-β-alanine is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-128915

Duocarmycin DM free base	DNA Alkylator/Crosslinker ADC Cytotoxin	Cancer
Duocarmycin DM free base, a DNA minor-groove alkylator, is an antibody drug conjugates (ADCs) toxin. Duocarmycin DM free base is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity.

HY-126684

Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA	Drug-Linker Conjugates for ADC	Cancer
Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA is a drug-linker conjugate for ADC by using the antitumor antibiotic, Duocarmycin SA, linked via Mal-PEG4-VC-PAB-DMEA-Seco.

HY-13631DS

Dxd-d5 Exatecan-d5 derivative for ADC	Topoisomerase ADC Cytotoxin	Cancer
Dxd-d₅ is a deuterium labeled Dxd. Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a) [1].

HY-126960

Mal-PEG1-acid	PROTAC Linkers ADC Linker	Cancer Inflammation/Immunology
Mal-PEG1-acid is is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-138856A

Thalidomide-NH-amido-PEG3-C2-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-amido-PEG3-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-130328

NH-bis-PEG2	ADC Linker PROTAC Linkers	Cancer
NH-bis-PEG2 is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH-bis-PEG2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-W127423

Methyl (+/-)-2-hydroxystearate METHYL 2-HYDROXYOCTADECANOATE		Others
Methyl (+/-)-2-hydroxystearateis a hydroxylated fatty acid methyl ester that broadens phase transitions in dimyristoylphosphatidylcholine (DMPC) lipid membranes. It has been used in the synthesis of lipid-nucleotide conjugated anti-HIV agents to increase the cleavage of phosphodiester bonds and the number of released intracellular nucleotides.

HY-136772

Pomalidomide-PEG1-NH2-1 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Others
Pomalidomide-PEG1-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate, consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand.

HY-15162

Monomethyl auristatin E MMAE; SGD-1010; Vedotin	Microtubule/Tubulin ADC Cytotoxin Apoptosis	Cancer
Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types.

HY-W018811S

N-Pyrazinylcarbonylphenylalanine-d8	Isotope-Labeled Compounds	Others
N-Pyrazinylcarbonylphenylalanine-d₈ is the deuterium labeled Deruxtecan. Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and amaleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

HY-145441

GEM–IB	Others	Cancer
GEM–IB is the conjugate of gemcitabine (GEM)-5'-phosphate with ibandronate (IB). GEM–IB as a single agent or in combination with Docetaxel (DTX) demonstrates reduced tumor burden, preservation of the bone architecture, and improved the survival in a murine model of osteosarcoma (OS).

HY-138856

Thalidomide-NH-amido-PEG3-C2-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-amido-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-138854A

Thalidomide-NH-amido-PEG1-C2-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-NH-amido-PEG1-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-111895B

Macropa-NH2 TFA	Others	Others
Macropa-NH2 TFA is the precursor of Macropa-NCS. Macropa-NCS is conjugated to trastuzumab as well as to the prostate-specific membrane antigen-targeting compound RPS-070 and is a promising therapeutic radionuclide applied in the treatment of soft-tissue metastases.

HY-33615

Methyl azetidine-3-carboxylate hydrochloride	ADC Linker PROTAC Linkers	Cancer
Methyl azetidine-3-carboxylate hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl azetidine-3-carboxylate hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs<

HY-P99352

Anetumab Anti-MSLN Antibody	Mesothelin	Cancer
Anetumab (Anti-MSLN Antibody) is an anti-mesothelin (MSLN) antibody. MSLN is a tumor-associated antigen. Anetumab can be used to synthesis Anetumab ravtansine, a MSLN-targeting antibody-drug conjugate (ADC). Anetumab can be used for the research of malignant tumor.

HY-P99334

Vorsetuzumab mafodotin Anti-Human CD70 Recombinant Antibody; SGN-75	Antibody-Drug Conjugates (ADCs) Microtubule/Tubulin	Cancer
Vorsetuzumab mafodotin (SGN-75) is an Auristatin-based anti-CD70 *antibody-drug conjugate* (ADC)**. Vorsetuzumab mafodotin consists of a humanized monoclonal antibody, Vorsetuzumab and an ADC cytotoxin MMAF. Vorsetuzumab mafodotin has antineoplastic activity.

HY-P99500

Cetuximab sarotalocan RM-1929; Cetuximab-IRDye-700DX	EGFR	Cancer
Cetuximab sarotalocan (Cetuximab-IRDye-700DX) is an IRdye700DX (near-infrared photosensitizing dye) conjugate of Cetuximab (anti-EGFR monoclonal antibody). Cetuximab sarotalocan can be used for head and neck cancers research.

HY-112599B

Pomalidomide-PEG4-C2-NH2 hydrochloride
E3 Ligase Ligand-Linker Conjugates Cancer