Search Result

Results for "

cyclin-dependent

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CDK (49) Cyclin G-associated Kinase (GAK) (2) Akt (2) Angiotensin-converting Enzyme (ACE) (1) Apoptosis (6) Autophagy (1) CFTR (1) Early 2 Factor (E2F) (1) ERK (1) FGFR (1) GSK-3 (6) JNK (2) PKA (1) PKC (2) SARS-CoV (1) STAT (4) TOPK (1) VEGFR (1) Virus Protease (1)
By Research Areas:	Cancer (45) Cardiovascular Disease (1) Infection (2) Inflammation/Immunology (3) Neurological Disease (4)

Inhibitors & Agonists

Peptides

Natural
Products

Recombinant Proteins

Antibodies

Targets Recommended: CDK Cyclin G-associated Kinase (GAK) Apical Sodium-Dependent Bile Acid Transporter CaMK SNIPERs DNA-PK VDAC SGLT PDK-1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-108136A

Bisindolylmaleimide X hydrochloride 2 Publications Verification BIM-X hydrochloride; Ro31-8425 hydrochloride	PKC CDK	Cardiovascular Disease
Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective protein kinase C (PKC) inhibitor. Bisindolylmaleimide X hydrochloride is a potent cyclin-dependent kinase 2 (CDK2) antagonist with an IC₅₀ of 200 nM .

HY-18299B

(S)-Purvalanol B

(S)-NG 95
Others Others

(S)-Purvalanol B is the S enantiomer of Purvalanol B. Purvalanol B is a cyclin-dependent kinase inhibitor.

(S)-Purvalanol B (S)-NG 95	Others	Others
(S)-Purvalanol B is the S enantiomer of Purvalanol B. Purvalanol B is a cyclin-dependent kinase inhibitor.

HY-149261

H1k	Autophagy CDK	Cancer
H1k, a Eudistomin Y derivative, is a lysosome-targeted antiproliferation agent. H1k increases the autophagy signal and downregulate the expression of cyclin-dependent kinase (CDK1) and cyclin B1. H1k can be used in research of cancer .

HY-146213

CDK4/6-IN-12	CDK	Cancer
CDK4/6-IN-12 is a potent cyclin-dependent kinase 4/6 (CDK4/6) inhibitor. CDK4/6-IN-12 has enzymatic inhibitory activity for CDK4 and CDK6 with IC₅₀ of 592.3 nM and 3090 nM, respectively. CDK4/6-IN-12 can be used for the research of cancer .

HY-139342

CDK7-IN-4	CDK	Cancer
CDK7-IN-4 (compound I) is a potent CDK7 (Cyclin-dependent kinase 7) inhibitor. CDK7-IN-4 shows anticancer activity. CDK7-IN-4 inhibits the in vitro growth of cancer cell lines from a variety of histologies including colon , breast , lung , ovary and stomach , in a dose dependent manner .

HY-162270

CDK2-IN-24

CDK Cancer

CDK2-IN-24 (compound 3f) is an inhibitor of cyclin-dependent kinase 2 with an elevated binding energy value .

CDK2-IN-24	CDK	Cancer
CDK2-IN-24 (compound 3f) is an inhibitor of cyclin-dependent kinase 2 with an elevated binding energy value .

HY-114177A

(S)-Ebvaciclib (S)-PF-06873600	Others	Cancer
(S)-PF-06873600 it the S enantiomer of PF-06873600. PF-06873600 is a selective and orally bioavailable inhibitor of cyclin-dependent kinase (CDK).

HY-153596

SNX7

Others Cancer

SNX7 is a Cyclin-Dependent Kinase Inhibitor (CDKI) pathway inhibitor. SNX7 can be used for research of senescence-related and other CDKI-related diseases .
HY-163170

FMF-04-159-R

CDK Cancer

FMF-04-159-R is a cyclin-dependent kinase CDK14 and CDK16 inhibitor with IC₅₀ values of 5.9 and 139.1 nM .
HY-108348

BML-259

CDK Neurological Disease

BML-259 is a potent cyclin-dependent kinase 5 (Cdk5) inhibitor, with IC₅₀s of 64 and 98 nM for Cdk5 and Cdk2, respectively .

SNX7	Others	Cancer
SNX7 is a Cyclin-Dependent Kinase Inhibitor (CDKI) pathway inhibitor. SNX7 can be used for research of senescence-related and other CDKI-related diseases .

FMF-04-159-R	CDK	Cancer
FMF-04-159-R is a cyclin-dependent kinase CDK14 and CDK16 inhibitor with IC₅₀ values of 5.9 and 139.1 nM .

BML-259	CDK	Neurological Disease
BML-259 is a potent cyclin-dependent kinase 5 (Cdk5) inhibitor, with IC₅₀s of 64 and 98 nM for Cdk5 and Cdk2, respectively .

HY-141687

NSC 107512	CDK Apoptosis	Cancer
NSC 107512 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9). NSC 107512 is a class of sangivamycin-like molecules (SLM). NSC 107512 inhibits growth and induces apoptosis of multiple myeloma tumors .

HY-19718

OTS964
OTS964 is an orally active, high affinity and selective TOPK inhibitor with an IC₅₀ of 28 nM . OTS964 is also a potent inhibitor of the cyclin-dependent kinase CDK11, which binds to CDK11B with a K_d of 40 nM .

HY-151371

CDK8-IN-10	CDK	Cancer
CDK8-IN-10 (compound 2) is a potent, selective cyclin-dependent kinase (CDK8) inhibitor with an IC₅₀ value of 8.25 nM. CDK8-IN-10 can be used for research of cancer .

HY-112358

GW8510	CDK	Neurological Disease Cancer
GW8510 is a potent cyclin-dependent kinase-2 (CDK2) inhibitor. GW8510 is also a ribonucleotide reductase M2 (RRM2) inhibitor. GW8510 exhibits neuroprotective and anticancer activities .

HY-162416

CDK7-IN-27

CDK Cancer

CDK7-IN-27 (Compound 37) is a selective inhibitor for cyclin-dependent kinase 7 (CDK7), with K_i of 3 nM. CDK7-IN-27 arrests the cell cycle at G0/G1 phase .

CDK7-IN-27	CDK	Cancer
CDK7-IN-27 (Compound 37) is a selective inhibitor for cyclin-dependent kinase 7 (CDK7), with K_i of 3 nM. CDK7-IN-27 arrests the cell cycle at G0/G1 phase .

HY-147409

Ulecaciclib	CDK	Cancer
Ulecaciclib is an orally activitive inhibitor of cyclin-dependent kinase (CDK), with K_i values of 0.62 μM (CDK2/Cyclin A), 0.2 nM (CDK4/Cyclin D1), 3 nM (CDK6/Cyclin D3), and 0.63 μM (CDK7/Cyclin H), respectively. Ulecaciclib can cross blood brain barrier and has good pharmacokinetic characteristics .

HY-114177

Ebvaciclib 2 Publications Verification PF-06873600	CDK	Cancer
PF-06873600 is a selective and orally bioavailable inhibitor of cyclin-dependent kinase (CDK), with K_i values of 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6, respectively. PF-06873600 has potential antineoplastic activity .

HY-141685

3-Methylthienyl-carbonyl-JNJ-7706621	CDK GSK-3 VEGFR FGFR	Cancer
3-Methylthienyl-carbonyl-JNJ-7706621 is a potent and selective inhibitor of cyclin-dependent kinase (CDK), with IC₅₀s of 6.4 nM and 2 nM for CDK1/cyclin B and CDK2/cyclin A, respectively. 3-Methylthienyl-carbonyl-JNJ-7706621 also shows potent inhibition of GSK-3 (IC₅₀=0.041 μM) and modest potency against CDK4, VEGF-R2, and FGF-R2 (IC₅₀=0.11, 0.13, 0.22 μM, respectively). 3-Methylthienyl-carbonyl-JNJ-7706621 can be used for the research of cancer .

HY-12467

OTS964 hydrochloride 5+ Cited Publications	TOPK CDK Apoptosis	Cancer
OTS964 hydrochloride is an orally active, high affinity and selective TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor with an IC₅₀ of 28 nM . OTS964 hydrochloride is also a potent inhibitor of the cyclin-dependent kinase CDK11, which binds to CDK11B with a K_d of 40 nM .

HY-148868

Akt1&PKA-IN-1	Akt PKA CDK	Others
Akt1&PKA-IN-1 is a potent dual Akt/PKA inhibitor with IC₅₀ values of 0.03 , 0.11 μM, and 9.8 μM for PKAa, Akt, and CDK2, respectively. Akt1&PKA-IN-1 is selective for cyclin-dependent kinase 2 (CDK2) .

HY-16462

CDK9-IN-2 5 Publications Verification	CDK	Cancer
CDK9-IN-2 is a special cyclin-dependent kinase 9 (CDK9) inhibitor, extracted from patent WO/2012131594A1, compound CDKI(8), has an IC₅₀ of 5 nM and 7 nM in H929 multiple myeloma(MM) cell line (72 hours) and A2058 skin cell line (72 hours), respectively.

HY-148868A

Akt1&PKA-IN-2	Akt CDK	Cancer
Akt1&PKA-IN-2 ((R)-29) is an inhibitor of PKB/AKT with cyclin-dependent kinase 2 (CDK2) selectivity. Akt1&PKA-IN-2 inhibits AKT1, PKAa and CDK2 ^a with IC₅₀ values of 0.007 µM, 0.01 µM and 0.69 µM, respectively .

HY-157647

1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC PC(18:0/22:4)	CDK Apoptosis	Cancer
1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC (PC(18:0/22:4)) is an inhibitor of cyclin-dependent kinases (CDKs).? 1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC induces apoptosis and inhibits the growth of various cancer cell lines .

HY-16559A

Riviciclib P276-00 free base	CDK	Cancer
Riviciclib (P276-00 free base) is a potent cyclin-dependent kinase (CDK) inhibitor, which inhibits CDK9-cyclinT1, CDK4-cyclin D1, and CDK1-cyclinB with IC₅₀s of 20 nM, 63 nM, and 79 nM, respectively . Riviciclib shows antitumor activity on cisplatin-resistant cells .

HY-N9561

Vanicoside B	CDK STAT	Cancer
Vanicoside B is a phenylpropanoyl sucrose derivative, can be isolated from the herb Persicaria dissitiflora. Vanicoside B targets cyclin-dependent kinase 8 (CDK8) and exhibits anti-tumor activity. The potential mechanism is Vanicoside B blocks CDK8-mediated signaling pathways and decreases the expression of epithelial-mesenchymal transition proteins, so that it leads to cell cycle arrest and apoptosis .

HY-153244

MFH290	CDK	Cancer
MFH290 is a potent and highly selective cyclin-dependent kinase 12/13 (CDK12/13) covalent inhibitor. MFH290 forms a covalent bond with Cys-1039 of CDK12 and exhibits excellent kinome selectivity and inhibits the phosphorylation of serine-2 in the C-terminal domain (CTD) of RNA-polymerase II (Pol II). MFH290 is used for cancer research .

HY-16559

Riviciclib hydrochloride 2 Publications Verification P276-00	CDK Apoptosis	Cancer
Riviciclib hydrochloride (P276-00) is a potent cyclin-dependent kinase (CDK) inhibitor, which inhibits CDK9-cyclinT1, CDK4-cyclin D1, and CDK1-cyclinB with IC₅₀s of 20 nM, 63 nM, and 79 nM, respectively . Riviciclib hydrochloride (P276-00) shows antitumor activity on cisplatin-resistant cells .

HY-145394

CDK7-IN-6	CDK	Cancer
CDK7-IN-6 is a potent and selective cyclin-dependent kinase (CDK7) inhibitor (IC₅₀≤100 nM), extracted from patent WO2019197549 A1, compound 210. CDK7-IN-6 is > 200-fold selective for CDK7 over CDK1, CDK2, and CDK5. CDK7-IN-6 can be used for the research of cancer .

HY-145599

Tanuxiciclib

CDK Cancer

Tanuxiciclib is a cyclin dependent kinase (CDK) inhibitor .
HY-145599A

Tanuxiciclib trihydrochloride

CDK Cancer

Tanuxiciclib trihydrochloride is a cyclin dependent kinase (CDK) inhibitor .

Tanuxiciclib	CDK	Cancer
Tanuxiciclib is a cyclin dependent kinase (CDK) inhibitor .

Tanuxiciclib trihydrochloride	CDK	Cancer
Tanuxiciclib trihydrochloride is a cyclin dependent kinase (CDK) inhibitor .

HY-15275

BMS-265246	CDK Angiotensin-converting Enzyme (ACE)	Infection Cancer
BMS-265246 is a potent and selective cyclin-dependent kinase CDK1 and CDK2 inhibitor, with IC₅₀ values of 6 and 9 nM, respectively. BMS-265246 inhibits CHI3L1 (chitinase 3-like-1) stimulation of ACE2 (angiotensin converting enzyme 2) and SPP (viral spike protein priming proteases). BMS-265246 can be used for ovarian cancer and COVID-19 research .

HY-145563

Eciruciclib

CDK Cancer

Eciruciclib is an antineoplastic and potent cyclin dependent kinase (CDK) inhibitor .

Eciruciclib	CDK	Cancer
Eciruciclib is an antineoplastic and potent cyclin dependent kinase (CDK) inhibitor .

HY-126675A

AS2863619	CDK STAT	Inflammation/Immunology
AS2863619 enables conversion of antigen-specific effector/memory T cells into Foxp3 ⁺ regulatory T (T_reg) cells for the treatment of various immunological diseases. AS2863619 is a potent, orally active cyclin-dependent kinase 8 (CDK8) and CDK19 inhibitor with IC₅₀s of 0.61 nM and 4.28 nM, respectively. STAT5 activation enhanced by AS2863619 inhibition of CDK8/19, which consequently activates the Foxp3 gene .

HY-147258

Culmerciclib

Cyclin G-associated Kinase (GAK) Cancer

Culmerciclib is a cyclin dependent kinase (CDK) inhibitor, and has antineoplastic activity .
HY-147258A

Culmerciclib maleate

Cyclin G-associated Kinase (GAK) Cancer

Culmerciclib maleate is a cyclin dependent kinase (CDK) inhibitor, and has antineoplastic activity .

Culmerciclib	Cyclin G-associated Kinase (GAK)	Cancer
Culmerciclib is a cyclin dependent kinase (CDK) inhibitor, and has antineoplastic activity .

Culmerciclib maleate	Cyclin G-associated Kinase (GAK)	Cancer
Culmerciclib maleate is a cyclin dependent kinase (CDK) inhibitor, and has antineoplastic activity .

HY-111932

Indirubin-5-sulfonate	CDK GSK-3	Cancer
Indirubin-5-sulfonate is a cyclin-dependent kinase (CDK) inhibitor, with IC₅₀ values of 55 nM, 35 nM, 150 nM, 300 nM and 65 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, and CDK5/p35, respectively . Indirubin-5-sulfonate also shows inhibitory activity against GSK-3β .

HY-126675

AS2863619 free base	CDK STAT	Inflammation/Immunology
AS2863619 free base enables conversion of antigen-specific effector/memory T cells into Foxp3 ⁺ regulatory T (T_reg) cells for the treatment of various immunological diseases. AS2863619 free base is a potent, orally active cyclin-dependent kinase 8 (CDK8) and CDK19 inhibitor with IC₅₀s of 0.61 nM and 4.28 nM, respectively. STAT5 activation enhanced by AS2863619 free base inhibition of CDK8/19, which consequently activates the Foxp3 gene .

HY-147716

CDK8-IN-6	CDK	Cancer
CDK8-IN-6 (compound 9) is a potent cyclin-dependent kinase 8 (CDK8) inhibitor with an K_d of 13 nM. CDK8-IN-6 shows cytotoxicity for MOLM-13, OCI-AML3, MV4-11, NRK and H9c2 cells with IC₅₀s of 11.2, 7.5, 8.6, 20.5, 12.5-25 µM, respectively. CDK8-IN-6 has the potential for the research of AML-cancer .

HY-11009

CGP60474 5 Publications Verification	CDK PKC	Cancer
CGP60474, a highly potent anti-endotoxemic agent, is a potent cyclin-dependent kinase (CDK) inhibitor (IC₅₀ values are 26, 3, 4, 216, 10, 200 and 13 nM for CDK1/B, CDK2/E, CDK2/A, CDK4/D, CDK5/p25, CDK7/H and CDK9/T, respectively). CGP60474 is a selective and ATP-competitive PKC inhibitor .

HY-121035

7BIO 7-Bromoindirubin-3-Oxime	CDK GSK-3	Neurological Disease
7BIO (7-Bromoindirubin-3-Oxime) is the derivate of indirubin. 7BIO (7-Bromoindirubin-3-Oxime) has inhibitory effects against cyclin-dependent kinase-5 (CDK5) and glycogen synthase kinase-3β (GSK3β). 7BIO (7-Bromoindirubin-3-Oxime) inhibits Aβ oligomer-induced neuroinflammation, synaptic impairments, tau hyper-phosphorylation, activation of astrocytes and microglia, and attenuates Aβ oligomer-induced cognitive impairments in mice ^[1].

HY-147717

CDK8-IN-7	CDK	Cancer
CDK8-IN-7 (compound 12) is a potent and selective cyclin-dependent kinase 8 (CDK8) inhibitor with an K_d of 3.5 nM. CDK8-IN-7 shows cytotoxicity for MOLM-13, OCI-AML3, MV4-11, NRK and H9c2 cells with IC₅₀s of 5.9, 4.8, 5.4, 16.2, 12.5-25 µM, respectively. CDK8-IN-7 has the potential for the research of AML-cancer .

HY-147386

CDK-IN-10

CDK Cancer

CDK-IN-10 (example 54) is a cyclin dependent kinase (CDK) inhibitor that can be used in cancer research .

CDK-IN-10	CDK	Cancer
CDK-IN-10 (example 54) is a cyclin dependent kinase (CDK) inhibitor that can be used in cancer research .

HY-139254

Indirubin-3′-oxime IDR3O; I3O	CDK GSK-3 JNK	Neurological Disease
Indirubin-3′-oxime (IDR3O), a synthetic derivative of indirubin, is a potent inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3β (GSK3β). Indirubin-3′-oxime directly inhibits the activity of all three isoforms of JNK (JNK1, JNK2, and JNK3), with IC₅₀s of 0.8 μM, 1.4 μM, and 1.0 μM, respectively. Indirubin-3′-oxime can enhance height growth via activation of Wnt/β-catenin signaling in chondrocytes .

HY-137432

Avotaciclib BEY1107	CDK	Cancer
Avotaciclib (BEY1107) is a potent and orally active inhibitor of cyclin dependent kinase 1 (CDK1). Avotaciclib can be used for the research of locally advanced or metastatic pancreatic cancer .

HY-137432A

Avotaciclib trihydrochloride 1 Publications Verification BEY1107 trihydrochloride	CDK	Cancer
Avotaciclib (BEY1107) trihydrochloride is a potent and orally active inhibitor of cyclin dependent kinase 1 (CDK1). Avotaciclib trihydrochloride can be used for the research of locally advanced or metastatic pancreatic cancer .

HY-145408

CDK7/9-IN-1	CDK	Cancer
CDK7/9-IN-1 is a cyclin-dependent kinases 7/9 (CDK7/9) inhibitor. CDK7/9-IN-1 selectively inhibits CDK7 over CDK9. CDK7/9-IN-1 inhibits CDK7 with IC₅₀s of 0.0656 μM and 0.00574 μM without pre-incubation and after 3 hours pre-incubation, respectively. CDK7/9-IN-1 inhibits CDK9 with an IC₅₀ of 2.14 μM after 3 hours pre-incubation. CDK7/9-IN-1 can be used for the research of cancer .

HY-13914

Roniciclib

BAY 1000394
CDK Cancer

Roniciclib is an orally bioavailable pan-cyclin dependent kinase (CDK) inhibitor, with IC₅₀s of 5-25 nM for CDK1, CDK2, CDK3, CDK4, CDK7 and CDK9.

HY-112363

Aloisine A RP107	CDK GSK-3 ERK JNK CFTR	Inflammation/Immunology Cancer
Aloisine A (RP107) is a a potent cyclin-dependent kinase (CDK) inhibitor with IC₅₀s of 0.15 μM, 0.12 μM, 0.4 μM, 0.16 μM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK5/p35, respectively. Aloisine A ininhibits GSK-3α (IC₅₀=0.5 μM) and GSK-3β (IC₅₀=1.5 μM). Aloisine A stimulates wild-type CFTR and mutated CFTR, with submicromolar affinity by a cAMP-independent mechanism. Aloisine A has the potential for CFTR-related diseases, including cystic fibrosis research .

HY-P1933A

[pSer2, pSer5, pSer7]-CTD TFA	CDK	Cancer
[pSer2, pSer5, pSer7]-CTD (TFA), a substrate for CDK7 (cyclin dependent protein kinase), is a phosphorylated polypeptide at ser2, ser5 and ser7 sites of RNA polymerase II carboxy-terminal domain (CTD) .

HY-160213

JA397

CDK Others

JA397 is a potent and selective inhibitor for the TAIRE family with cellular activity ranging from IC₅₀ values of 21 nM to 307 nM .

Species:	Human (61) Mouse (1)
Tag:	His (37) Tag Free (15) Avi (1) GST (39) Flag (30)
Source:	HEK293 (1) Sf9 insect cells (53) E. coli (8)

Cat. No.	Compare	Product Name	Species	Source

HY-P702755

	CDK10-CCNM Protein, Human (sf9, GST, Flag) CDK10; cyclin-dependent kinase 10; cyclin dependent kinase (CDC2 like) 10; PISSLRE; CDC2-related protein kinase; cell division protein kinase 10; cyclin-dependent kinase (CDC2-like) 10; cyclin-dependent kinase related protein; serine/threonine protein kinase PISSLRE; serine/threonine-protein kinase PISSLRE	Human	Sf9 insect cells

HY-P701662

	CKS2 Protein, Human CKS2; cyclin-dependent kinases regulatory subunit 2; CKS-2	Human	E. coli
	CKS2 protein intricately binds to TEK/TIE2 to regulate ANGPT1 signaling. Its binding induces receptor tyrosine phosphorylation, affecting downstream cellular responses. CKS2 Protein, Human is the recombinant human-derived CKS2 protein, expressed by E. coli , with tag free. The total length of CKS2 Protein, Human is 79 a.a., .

HY-P70037

	CDKN1B Protein, Human (His) rHucyclin-dependent kinase inhibitor 1B/CDKN1B, His; cyclin-dependent Kinase Inhibitor 1B; cyclin-dependent Kinase Inhibitor p27; p27Kip1; CDKN1B; KIP1	Human	E. coli
	The CDKN1B protein is a key cell cycle regulator that inhibits CDK2 when bound to cyclin A, thereby inhibiting G1 phase progression. It exhibits significant inhibitory effects on cyclin E- and cyclin A-CDK2 complexes. CDKN1B Protein, Human (His) is the recombinant human-derived CDKN1B protein, expressed by E. coli , with N-6*His labeled tag. The total length of CDKN1B Protein, Human (His) is 198 a.a., with molecular weight of ~30.0 kDa.

HY-P701661

	CKS1 Protein, Human CKS1B; cyclin-dependent kinases regulatory subunit 1; CKS-1	Human	E. coli
	CKS1 Protein is vital, binding to the catalytic subunit of cyclin-dependent kinases and serving as an essential factor for their biological function. Forming a homohexamer, CKS1's potential to bind six kinase subunits underscores intricate regulatory mechanisms. This highlights CKS1's importance in modulating cyclin-dependent kinase activity, emphasizing its crucial role in facilitating the proper functioning of these key cellular regulators. CKS1 Protein, Human is the recombinant human-derived CKS1 protein, expressed by E. coli , with tag free. The total length of CKS1 Protein, Human is 79 a.a., .

HY-P702699

	CDK19-CCNC-MED12 Protein, Human (sf9, GST, Flag, His) CDC2L6; CDK19; cyclin dependent kinase 19; CDK11; CDC2L6; bA346C16.3; cyclin-dependent kinase 19; CDC2-related protein kinase 6; CDK8-like cyclin-dependent kinase; cell division cycle 2-like 6 (CDK8-like); cell division cycle 2-like protein kinase 6; cell division protein kinase 19; cyclin dependent kinase 19 variant 2; cyclin-dependent kinase (CDC2-like) 11; cyclin-dependent kinase 11; death-preventing kinase; EC 2.7.11.22	Human	Sf9 insect cells

HY-P70034

	CDKN2C Protein, Human (His) rHucyclin-dependent kinase 4 inhibitor C/CDKN2C, His; cyclin-dependent Kinase 4 Inhibitor C; cyclin-dependent Kinase 6 Inhibitor; p18-INK4c; p18-INK6; CDKN2C; CDKN6	Human	E. coli
	The CDKN2C protein (also known as p18) interacts strongly with CDK6 and weakly with CDK4. Its functional effects inhibit cell growth and proliferation and are significantly related to the presence of endogenous retinoblastoma protein RB. CDKN2C Protein, Human (His) is the recombinant human-derived CDKN2C protein, expressed by E. coli , with N-6*His labeled tag. The total length of CDKN2C Protein, Human (His) is 168 a.a., with molecular weight of ~17.0 kDa.

HY-P72785

	CDKN2A Protein, Human cyclin-dependent kinase inhibitor 2A; CDK4I; MTS-1; p16INK4A	Human	E. coli
	CDKN2A Protein, a potent negative regulator of cell proliferation, forms strong interactions with CDK4 and CDK6, hindering their association with cyclins D and retinoblastoma protein phosphorylation. Acting in a heterodimeric manner, predominantly with CDK6, CDKN2A inhibits cyclin D-CDK4 kinase activity and interacts with ISCO2, contributing to its cell cycle regulatory role. CDKN2A Protein, Human is the recombinant human-derived CDKN2A protein, expressed by E. coli , with tag free. The total length of CDKN2A Protein, Human is 155 a.a., with molecular weight of ~19.12 kDa.

HY-P76247

CDKL2 Protein, Human (sf9, His)

cyclin-dependent kinase-like 2; Protein kinase p56 KKIAMRE; CDKL2
Human Sf9 insect cells

HY-P74659

	p19INK4d Protein, Human (His) cyclin-dependent kinase 4 inhibitor D; p19-INK4d; CDKN2D	Human	E. coli
	The p19INK4d protein, a potent inhibitor, strongly interacts with CDK4 and CDK6, effectively impeding their activity. Specifically interacting with CDK6, p19INK4d reinforces its role as a regulator of cyclin-dependent kinase activity. This crucial role in cell cycle regulation involves restraining CDK4 and CDK6 functions, contributing to the modulation of key cellular processes. p19INK4d Protein, Human (GST) is the recombinant human-derived p19INK4d protein, expressed by E. coli , with N-GST labeled tag. The total length of p19INK4d Protein, Human (GST) is 166 a.a., with molecular weight of ~46 kDa.

HY-P76536

	PCTAIRE1 Protein, Human (sf9, GST) cyclin-dependent kinase 16; PCTAIRE-motif protein kinase 1; CDK16; PCTAIRE1; PCTK1	Human	Sf9 insect cells
	PCTAIRE1 protein is a multifunctional kinase that plays a key role in vesicle-mediated transport and regulation of GH1 release, emphasizing neuroendocrine function. Its involvement includes NSF phosphorylation, influencing vesicle dynamics, and important contributions to spermatogenesis and reproductive processes. PCTAIRE1 Protein, Human (sf9, GST) is the recombinant human-derived PCTAIRE1 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of PCTAIRE1 Protein, Human (sf9, GST) is 496 a.a., with molecular weight of ~73 kDa.

HY-P702601

CDK6 Protein, Human (Sf9, His-Avi)

cyclin-dependent kinase 6; Cell division protein kinase 6; CDKN6; EC:2.7.11.22
Human Sf9 insect cells

HY-P74257

	CDK1-CCNE1 Heterodimer Protein, Human (sf9, His-GST) cyclin-dependent kinase 1; CDK1; CDC2; G1/S-specific cyclin-E1; CCNE1	Human	Sf9 insect cells
	The FGF-9 protein undergoes autoproteolysis and cholesterol attachment in the endoplasmic reticulum. It acts as a morphogen during development, inducing ventral cell fate, participating in limb bud patterning, and aiding in axon guidance. FGF-9 binds to the PTCH1 receptor and activates target gene transcription when in association with SMO, while PTCH1 represses SMO signaling in the absence of FGF-9. CDK1-CCNE1 Heterodimer Protein, Human (sf9, His-GST) is a recombinant protein dimer complex containing human-derived CDK1-CCNE1 Heterodimer protein, expressed by Sf9 insect cells, with N-10*His, N-GST labeled tag. CDK1-CCNE1 Heterodimer Protein, Human (sf9, His-GST), has molecular weight of ~109.7 (60.4+49.3) kDa.

HY-P75668

	CDK1 Protein, Human (sf9, GST) cyclin-dependent kinase 1; CDK1; p34 protein kinase; CDC2; CDC28A; CDKN1; P34CDC2	Human	Sf9 insect cells
	The CDK1/CDC2-cyclin-B complex is a key regulator in the cell cycle. It plays an important role in cell division and development and regulates a variety of cellular activities, including chromosome segregation, nuclear membrane rupture, cytokinesis, etc. The activity of CDK1 is regulated by a variety of phosphorylation and dephosphorylation, thereby controlling the progression of the cell cycle and the DNA repair process. CDK1 Protein, Human (sf9, GST) is the recombinant human-derived CDK1 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of CDK1 Protein, Human (sf9, GST) is 297 a.a., with molecular weight of ~53 kDa.

HY-P75669

	CDK1 Protein, Mouse (sf9, His-GST) cyclin-dependent kinase 1; CDK1; p34 protein kinase; CDC2; CDC28A; CDKN1; P34CDC2	Mouse	Sf9 insect cells
	The CDK1 protein centrally controls the eukaryotic cell cycle, coordinating the G2-M transition and mitotic events. It interacts with a variety of cell cycle proteins, phosphorylates a variety of substrates, and affects cell cycle regulation, DNA repair, and apoptosis. CDK1 Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived CDK1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of CDK1 Protein, Mouse (sf9, His-GST) is 297 a.a., with molecular weight of ~57 kDa.

HY-P70014

	CDK2 Protein, Human (His) rHucyclin-dependent kinase 2/CDK2, His; cyclin-dependent Kinase 2; Cell Division Protein Kinase 2; p33 Protein Kinase; CDK2; CDKN2	Human	E. coli
	CDK2 is an important serine/threonine protein kinase that plays a critical regulatory role in the cell cycle, especially during meiosis. It phosphorylates various substrates (CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2) and coordinates centrosome duplication and initiation of DNA synthesis at the G1-S transition. CDK2 Protein, Human (His) is the recombinant human-derived CDK2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of CDK2 Protein, Human (His) is 298 a.a., with molecular weight of 32-35 kDa.

HY-P701364

	CDK3-CCNE1 Heterodimer Protein, Human (Sf9) CDK3; CCNE1; cyclin-dependent kinase 3; Cell division protein kinase 3; G1/S-specific cyclin-E1	Human	Sf9 insect cells
	CDK3 protein is a serine/threonine protein kinase that plays a key role in regulating the eukaryotic cell cycle, especially affecting the G0-G1 and G1-S transitions. It interacts with CCNC/cyclin-C during interphase and phosphorylates substrates such as histone H1, ATF1, RB1, and CABLES1. CDK3-CCNE1 Heterodimer Protein, Human (Sf9) is a recombinant protein dimer complex containing human-derived CDK3-CCNE1 Heterodimer protein, expressed by Sf9 insect cells , with tag free.

HY-P70014A

	CDK2 Protein, Human (N-His) rHucyclin-dependent kinase 2/CDK2, His; cyclin-dependent Kinase 2; Cell Division Protein Kinase 2; p33 Protein Kinase; CDK2; CDKN2	Human	E. coli
	CDK2 is an important serine/threonine protein kinase that plays a critical regulatory role in the cell cycle, especially during meiosis. It phosphorylates various substrates (CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2) and coordinates centrosome duplication and initiation of DNA synthesis at the G1-S transition. CDK2 Protein, Human (N-His) is the recombinant human-derived CDK2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of CDK2 Protein, Human (N-His) is 297 a.a., with molecular weight of approximately 32.65 kDa.

HY-P702680

CDK3-CCNC Protein, Human (sf9, GST, Flag, His)

CDK3; CCNE1; cyclin-dependent kinase 3; Cell division protein kinase 3; G1/S-specific cyclin-E1
Human Sf9 insect cells
HY-P702681

CDK3-CCNE2 Protein, Human (sf9, GST, Flag, His)

CDK3; CCNE1; cyclin-dependent kinase 3; Cell division protein kinase 3; G1/S-specific cyclin-E1
Human Sf9 insect cells
HY-P702684

CDK4-CCND3 Protein, Human (sf9, GST, His)

CDK4; cyclin-dependent kinase 4; PSK J3; cell division protein kinase 4; CMM3; PSK-J3; MGC14458
Human Sf9 insect cells

HY-P701365

	CDK3-CCNE1 Heterodimer Protein, Human (Sf9, GST, FLAG, His) CDK3; CCNE1; cyclin-dependent kinase 3; Cell division protein kinase 3; G1/S-specific cyclin-E1	Human	Sf9 insect cells
	CDK3 protein is a serine/threonine protein kinase that plays a key role in regulating the eukaryotic cell cycle, especially affecting the G0-G1 and G1-S transitions. It interacts with CCNC/cyclin-C during interphase and phosphorylates substrates such as histone H1, ATF1, RB1, and CABLES1. CDK3-CCNE1 Heterodimer Protein, Human (Sf9, GST, FLAG, His) is a recombinant protein dimer complex containing human-derived CDK3-CCNE1 Heterodimer protein, expressed by Sf9 insect cells , with N-6*His, N-Flag, N-GST labeled tag.

HY-P702682

CDK4-CCND1 Protein, Human (sf9, GST, Flag, His)

CDK4; cyclin-dependent kinase 4; PSK J3; cell division protein kinase 4; CMM3; PSK-J3; MGC14458
Human Sf9 insect cells
HY-P702683

CDK4-CCND2 Protein, Human (sf9, GST, Flag, His)

CDK4; cyclin-dependent kinase 4; PSK J3; cell division protein kinase 4; CMM3; PSK-J3; MGC14458
Human Sf9 insect cells

HY-P701367

	CDK6-CCND2 Heterodimer Protein, Human (Sf9) CDK6; CCND2; cyclin-dependent kinase 6; Cell division protein kinase 6; Serine/threonine-protein kinase PLSTIRE; G1/S-specific cyclin-D2	Human	Sf9 insect cells
	The CDK6ic complex is an important serine/threonine protein kinase that regulates cell cycle progression and differentiation, promoting the G1/S transition by phosphorylating substrates such as pRB/RB1 and NPM1. It interacts with D-type G1 cyclins during interphase to form active pRB/RB1 kinase, which controls cell cycle entry. CDK6-CCND2 Heterodimer Protein, Human (Sf9) is a recombinant protein dimer complex containing human-derived CDK6-CCND2 Heterodimer protein, expressed by Sf9 insect cells , with tag free.

HY-P701369

	CDK6-CCND3 Heterodimer Protein, Human (Sf9) CDK6; CCND3; cyclin-dependent kinase 6; Cell division protein kinase 6; Serine/threonine-protein kinase PLSTIRE; G1/S-specific cyclin-D3	Human	Sf9 insect cells
	The CDK6ic complex is an important serine/threonine protein kinase that regulates cell cycle progression and differentiation, promoting the G1/S transition by phosphorylating substrates such as pRB/RB1 and NPM1. It interacts with D-type G1 cyclins during interphase to form active pRB/RB1 kinase, which controls cell cycle entry. CDK6-CCND3 Heterodimer Protein, Human (Sf9) is a recombinant protein dimer complex containing human-derived CDK6-CCND3 Heterodimer protein, expressed by Sf9 insect cells , with tag free.

HY-P701368

	CDK6-CCND2 Heterodimer Protein, Human (Sf9, GST, FLAG, His) CDK6; CCND2; cyclin-dependent kinase 6; Cell division protein kinase 6; Serine/threonine-protein kinase PLSTIRE; G1/S-specific cyclin-D2	Human	Sf9 insect cells
	The CDK6ic complex is an important serine/threonine protein kinase that regulates cell cycle progression and differentiation, promoting the G1/S transition by phosphorylating substrates such as pRB/RB1 and NPM1. It interacts with D-type G1 cyclins during interphase to form active pRB/RB1 kinase, which controls cell cycle entry. CDK6-CCND2 Heterodimer Protein, Human (Sf9, GST, FLAG, His) is a recombinant protein dimer complex containing human-derived CDK6-CCND2 Heterodimer protein, expressed by Sf9 insect cells , with N-Flag, N-8*His, N-GST labeled tag.

HY-P701370

	CDK6-CCND3 Heterodimer Protein, Human (Sf9, GST, His) CDK6; CCND3; cyclin-dependent kinase 6; Cell division protein kinase 6; Serine/threonine-protein kinase PLSTIRE; G1/S-specific cyclin-D3	Human	Sf9 insect cells
	The CDK6ic complex is an important serine/threonine protein kinase that regulates cell cycle progression and differentiation, promoting the G1/S transition by phosphorylating substrates such as pRB/RB1 and NPM1. It interacts with D-type G1 cyclins during interphase to form active pRB/RB1 kinase, which controls cell cycle entry. CDK6-CCND3 Heterodimer Protein, Human (Sf9, GST, His) is a recombinant protein dimer complex containing human-derived CDK6-CCND3 Heterodimer protein, expressed by Sf9 insect cells , with N-10*His, N-GST labeled tag.

HY-P702687

	CDK6-CCND1 Protein, Human (sf9, GST, Flag, His) CDK6; CCND2; cyclin-dependent kinase 6; Cell division protein kinase 6; Serine/threonine-protein kinase PLSTIRE; G1/S-specific cyclin-D2	Human	Sf9 insect cells

HY-P702675

	CDK2-CCNA2 Protein, Human (sf9, GST, His) CDK2; cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase; cell division protein kinase 2; p33(CDK2)	Human	Sf9 insect cells

HY-P702676

	CDK2-CCND1 Protein, Human (sf9, GST, Flag, His) CDK2; cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase; cell division protein kinase 2; p33(CDK2)	Human	Sf9 insect cells

HY-P702677

	CDK2-CCNE1 Protein, Human (sf9, GST, His, Flag) CDK2; cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase; cell division protein kinase 2; p33(CDK2)	Human	Sf9 insect cells

HY-P702678

	CDK2-CCNE2 Protein, Human (sf9, GST, Flag, His) CDK2; cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase; cell division protein kinase 2; p33(CDK2)	Human	Sf9 insect cells

HY-P702679

	CDK2-CCNO Protein, Human (sf9, GST, Flag, His) CDK2; cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase; cell division protein kinase 2; p33(CDK2)	Human	Sf9 insect cells

HY-P702685

	CDK5-p25 Protein, Human (sf9, GST, His, Flag) CDK5; cyclin-dependent kinase 5; PSSALRE; TPKII catalytic subunit; protein kinase CDK5 splicing; cell division protein kinase 5; serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit	Human	Sf9 insect cells

HY-P702686

	CDK5-p35 Protein, Human (sf9, GST, His, Flag) CDK5; cyclin-dependent kinase 5; PSSALRE; TPKII catalytic subunit; protein kinase CDK5 splicing; cell division protein kinase 5; serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit	Human	Sf9 insect cells

HY-P7850

	CDK2AP2 Protein, Human (HEK293, His) rHucyclin-dependent kinase 2-associated protein 2/CDK2AP2, His; cyclin-dependent kinase 2-associated protein 2; CDK2-associated protein 2; DOC-1-related protein; DOC-1R; CDK2AP2; DOC1R	Human	HEK293
	CDK2AP2 protein, a vital component of the NuRD complex, actively engages in chromatin remodeling. It inhibits G1/S phase transition by suppressing CDK2, impeding CDK2's interaction with cyclin E or A. Beyond cell cycle control, CDK2AP2 is crucial for ESC self-renewal, ensuring survival during differentiation, and regulates microtubule organization in metaphase II oocytes. Part of the NuRD complex, CDK2AP2 collaborates with proteins like MTA1, MTA2, HDAC1, and others, showcasing its multifaceted regulatory functions. CDK2AP2 Protein, Human (HEK293, His) is the recombinant human-derived CDK2AP2 protein, expressed by HEK293, with C-6*His labeled tag. The total length of CDK2AP2 Protein, Human (HEK293, His) is 126 a.a., with molecular weight of ~26.0 kDa.

HY-P701374

	CDK9-CCNK Heterodimer Protein, Human (Sf9) CDK9; CCNK; cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; cyclin-K	Human	Sf9 insect cells
	The CDK9 protein plays a central role in transcriptional regulation, promoting the transition from ineffective to efficient elongation by phosphorylating POLR2A, SUPT5H, and RDBP. As part of the CDK9/cyclin-T complex, it participates in phosphorylation events affecting EP300, MYOD1, RPB1/POLR2A, AR, DSIF, and NELFE. CDK9-CCNK Heterodimer Protein, Human (Sf9) is a recombinant protein dimer complex containing human-derived CDK9-CCNK Heterodimer protein, expressed by Sf9 insect cells , with tag free.

HY-P701366

	CDK6-CCND1 Heterodimer Protein, Human (Sf9) CDK6; CCND1; cyclin-dependent kinase 6; Cell division protein kinase 6; Serine/threonine-protein kinase PLSTIRE; G1/S-specific cyclin-D1; B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; PRAD1 oncogene	Human	Sf9 insect cells
	The CDK6ic complex is an important serine/threonine protein kinase that regulates cell cycle progression and differentiation, promoting the G1/S transition by phosphorylating substrates such as pRB/RB1 and NPM1. It interacts with D-type G1 cyclins during interphase to form active pRB/RB1 kinase, which controls cell cycle entry. CDK6-CCND1 Heterodimer Protein, Human (Sf9) is a recombinant protein dimer complex containing human-derived CDK6-CCND1 Heterodimer protein, expressed by Sf9 insect cells , with tag free.

HY-P701375

	CDK9-CCNK Heterodimer Protein, Human (Sf9, GST, FLAG) CDK9; CCNK; cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; cyclin-K	Human	Sf9 insect cells
	The CDK9 protein plays a central role in transcriptional regulation, promoting the transition from ineffective to efficient elongation by phosphorylating POLR2A, SUPT5H, and RDBP. As part of the CDK9/cyclin-T complex, it participates in phosphorylation events affecting EP300, MYOD1, RPB1/POLR2A, AR, DSIF, and NELFE. CDK9-CCNK Heterodimer Protein, Human (Sf9, GST, FLAG) is a recombinant protein dimer complex containing human-derived CDK9-CCNK Heterodimer protein, expressed by Sf9 insect cells , with N-Flag, N-GST labeled tag.

HY-P702689

	CDK9-CCNT1 Protein, Human (sf9, GST, His) CDK9; CCNK; cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; cyclin-K	Human	Sf9 insect cells

HY-P702690

	CDK9-CCNT2 Protein, Human (sf9, GST, Flag, His) CDK9; CCNK; cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; cyclin-K	Human	Sf9 insect cells

HY-P701363

	CDK19-CCNC-MED12 Protein, Human (Sf9) CDK19; CCNC; MED12; cyclin-dependent kinase 19; CDC2-related protein kinase 6; Cell division cycle 2-like protein kinase 6; Cell division protein kinase 19; cyclin-dependent kinase 11; Death-preventing kinase; cyclin-C; SRB11 homolog; hSRB11; Mediator of RNA polymerase II transcription subunit 12; Activator-recruited cofactor 240 kDa component; ARC240; CAG repeat protein 45; Mediator complex subunit 12; OPA-containing protein; Thyroid hormone receptor-associated protein complex 230 kDa component; Trap230; Trinucleotide repeat-containing gene 11 protein	Human	Sf9 insect cells
	CDK19 plays a key role in cellular homeostasis and developmental programming. CDK19 can interact with p53 to inhibit p53-mediated transcription of p21, and regulates the proliferation of hematopoietic stem cells and acute myeloid leukemia cells. Besides, CDK19 is the paralog of CDK8. CDK8 and CDK19 can cooperate with each other in stimulating NFκB-induced transcription and Dengue virus replication. CDK19-CCNC-MED12 Protein, Human (Sf9) is the recombinant human-derived CDK19-CCNC-MED12 protein, expressed by Sf9 insect cells , with tag free. ,

HY-P701360

	CDK12-CCNK Heterodimer Protein, Human (Sf9) CDK12; CCNK; cyclin-dependent kinase 12; Cdc2-related kinase; arginine/serine-rich; CrkRS; Cell division cycle 2-related protein kinase 7; CDC2-related protein kinase 7; Cell division protein kinase 12; hCDK12; cyclin-K	Human	Sf9 insect cells
	The CDK12 protein is a cyclin-dependent kinase that critically phosphorylates the C-terminal domain of POLR2A, thereby regulating transcription elongation. It selectively targets "Ser-5" phosphorylated at "Ser-7" in the CTD repeat and can also target "Ser-2". CDK12-CCNK Heterodimer Protein, Human (Sf9) is a recombinant protein dimer complex containing human-derived CDK12-CCNK Heterodimer protein, expressed by Sf9 insect cells , with tag free.

HY-P701377

	CDK9-CCNT2 Heterodimer Protein, Human (Sf9) CDK9; CCNT2; cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; cyclin-T2; CycT2	Human	Sf9 insect cells
	The CDK9 protein plays a central role in transcriptional regulation, promoting the transition from ineffective to efficient elongation by phosphorylating POLR2A, SUPT5H, and RDBP. As part of the CDK9/cyclin-T complex, it participates in phosphorylation events affecting EP300, MYOD1, RPB1/POLR2A, AR, DSIF, and NELFE. CDK9-CCNT2 Heterodimer Protein, Human (Sf9) is a recombinant protein dimer complex containing human-derived CDK9-CCNT2 Heterodimer protein, expressed by Sf9 insect cells , with tag free.

HY-P702688

	CDK7-CCNH-MNAT1 Protein, Human (sf9, GST, His, Flag) CDK7; cyclin-dependent kinase 7; cyclin dependent kinase 7 (homolog of Xenopus MO15 cdk activating kinase) , cyclin dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk activating kinase); CAK; CAK1; CDKN7; MO15; STK1; p39 Mo15; protein kinase; 39 KDa protein kinase; kinase subunit of CAK; CDK-activating kinase 1; serine/threonine kinase stk1; cell division protein kinase 7; serine/threonine protein kinase 1; serine/threonine-protein kinase 1; serine/threonine protein kinase MO15	Human	Sf9 insect cells

HY-P701361

	CDK12-CCNK Heterodimer Protein, Human (Sf9, GST, FLAG) CDK12; CCNK; cyclin-dependent kinase 12; Cdc2-related kinase; arginine/serine-rich; CrkRS; Cell division cycle 2-related protein kinase 7; CDC2-related protein kinase 7; Cell division protein kinase 12; hCDK12; cyclin-K	Human	Sf9 insect cells
	The CDK12 protein is a cyclin-dependent kinase that critically phosphorylates the C-terminal domain of POLR2A, thereby regulating transcription elongation. It selectively targets "Ser-5" phosphorylated at "Ser-7" in the CTD repeat and can also target "Ser-2". CDK12-CCNK Heterodimer Protein, Human (Sf9, GST, FLAG) is a recombinant protein dimer complex containing human-derived CDK12-CCNK Heterodimer protein, expressed by Sf9 insect cells , with N-Flag, N-GST labeled tag.

HY-P701376

	CDK9-CCNT1 Heterodimer Protein, Human (Sf9) CDK9; CCNT1; cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; cyclin-T1; CycT1; cyclin-T	Human	Sf9 insect cells
	The CDK9 protein plays a central role in transcriptional regulation, promoting the transition from ineffective to efficient elongation by phosphorylating POLR2A, SUPT5H, and RDBP. As part of the CDK9/cyclin-T complex, it participates in phosphorylation events affecting EP300, MYOD1, RPB1/POLR2A, AR, DSIF, and NELFE. CDK9-CCNT1 Heterodimer Protein, Human (Sf9) is a recombinant protein dimer complex containing human-derived CDK9-CCNT1 Heterodimer protein, expressed by Sf9 insect cells , with tag free.

HY-P702692

	CDK12-CCNT1 Protein, Human (sf9, GST, Flag, His) CDK12; CCNK; cyclin-dependent kinase 12; Cdc2-related kinase; arginine/serine-rich; CrkRS; Cell division cycle 2-related protein kinase 7; CDC2-related protein kinase 7; Cell division protein kinase 12; hCDK12; cyclin-K	Human	Sf9 insect cells

HY-P702696

	CDK16-CCNY Protein, Human (sf9, GST, Flag) CDK16; cyclin-dependent kinase 16; PCTAIRE protein kinase 1 , PCTK1; FLJ16665; PCTAIRE; PCTAIRE1; PCTGAIRE; serine/threonine protein kinase; PCTAIRE-motif protein kinase 1; cell division protein kinase 16; serine/threonine-protein kinase PCTAIRE-1; PCTK1	Human	Sf9 insect cells

HY-P702697

	CDK17-CCNY Protein, Human (sf9, GST, Flag) CDK17; cyclin-dependent kinase 17; PCTAIRE protein kinase 2 , PCTK2; PCTAIRE2; PCTAIRE-motif protein kinase 2; cell division protein kinase 17; protein kinase cdc2-related PCTAIRE-2; serine/threonine-protein kinase PCTAIRE-2; PCTK2	Human	Sf9 insect cells

Cat. No.	Product Name	Application	Reactivity

HY-P81578

CDK8 Antibody (YA1323)

cyclin-dependent kinase 8
IHC-P Human, Mouse
HY-P83209

p57 Kip2 Antibody (YA2954)

CDKN1C; KIP2; cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor p57; p57Kip2
WB, IHC-P, ICC/IF, IP Human, Mouse, Rat

HY-P81003

CDKN2C Antibody CDKN2C; CDKN6; cyclin-dependent kinase 4 inhibitor C; cyclin-dependent kinase 6 inhibitor; p18-INK4c; p18-INK6	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat
CDKN2C Antibody is an unconjugated, approximately 15 kDa, rabbit-derived, anti-CDKN2C monoclonal antibody. CDKN2C Antibody can be used for: WB, IHC-P, ICC/IF, IP expriments in background without labeling.

HY-P81749

Phospho-p27 Kip 1 (Ser10) Antibody (YA1494)

CDKN1B; KIP1; cyclin-dependent kinase inhibitor 1B; cyclin-dependent kinase inhibitor p27; p27Kip1
WB, IHC-P, IP Human, Mouse, Rat

HY-P80615

CDKN2A Antibody CDKN2A; CDKN2; MTS1; cyclin-dependent kinase inhibitor 2A; isoforms 1/2/3; cyclin-dependent kinase 4 inhibitor A; CDK4I; Multiple tumor suppressor 1; MTS-1; p16-INK4a; p16-INK4; p16INK4A	WB, IP	Human, Mouse
CDKN2A Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 17 kDa, targeting to CDKN2A. It can be used for WB,IP assays with tag free, in the background of Human, Mouse.

HY-P80798

Phospho-CDK2 (Tyr15) Antibody CDK2; CDKN2; cyclin-dependent kinase 2; Cell division protein kinase 2; p33 protein kinase	WB, IP	Human, Hamster, Rat
Phospho-CDK2 (Tyr15) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 34 kDa, targeting to Phospho-CDK2 (Tyr15). It can be used for WB,IP assays with tag free, in the background of Human, Hamster, Rat.

HY-P81818

CDKN2A/p14ARF Antibody (YA1563)

CDKN2A; CDKN2; MLM; Alternative reading frame （ARF）; cyclin-dependent kinase inhibitor 2A; P14arf
WB, ICC/IF, IP, FC Human

HY-P80613

CDK5 Antibody (YA796) Cdk 5; Cdk5; CDK5_HUMAN; Cell division protein kinase 5; Crk6; cyclin dependent kinase 5; cyclin-dependent kinase 5; Protein kinase CDK5 splicing; PSSALRE; Serine threonine protein kinase PSSALRE; Serine/threonine-protein kinase PSSALRE; Tau protein kinas	WB, ICC/IF	Human, Mouse, Rat, Monkey
CDK5 Antibody (YA796) is a non-conjugated and Mouse origined monoclonal antibody about 33 kDa, targeting to CDK5 (2E8). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat, Monkey.

HY-P80611

CDK1 Antibody CDK1; CDC2; CDC28A; CDKN1; P34CDC2; cyclin-dependent kinase 1; CDK1; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase	WB, IP	Human
CDK1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 34 kDa, targeting to CDK1. It can be used for WB,IP assays with tag free, in the background of Human.

HY-P80774

p21 Antibody CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21	WB, ICC/IF	Human, Mouse, Rat
p21 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 18 kDa, targeting to p21. It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P80773

p21 Antibody (YA254) CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21	WB	Human, Mouse
p21 Antibody (YA254) is a non-conjugated and Rabbit origined monoclonal antibody about 18 kDa, targeting to p21. It can be used for WB assays with tag free, in the background of Human, Mouse.

HY-P80796

Phospho-CDK1 (Tyr15) Antibody CDK1; CDC2; CDC28A; CDKN1; P34CDC2; cyclin-dependent kinase 1; CDK1; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase	WB	Human, Mouse, Rat
Phospho-CDK1 (Tyr15) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 34 kDa, targeting to Phospho-CDK1 (Tyr15). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P80389

Cdk7 Antibody CDK7_HUMAN; cyclin-dependent kinase 7; EC:2.7.11.22; EC:2.7.11.23; CDK7; CAK; CAK1; CDKN7; MO15; STK1; 39 kDa protein kinase (p39 Mo15); CDK-activating kinase 1; Cell division protein kinase 7; Serine/threonine-protein kinase 1; TFIIH basal transcription factor complex kinase subunit	WB；ELISA；IHC-P；IHC-F；ICC；IF	Human, Mouse, Rat
Cdk7 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 39 kDa, targeting to Cdk7. It can be used for WB,ICC/IF,IHC-P,FC assays with tag free, in the background of Human.

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